References analysis of the Wikipedia article "MTORC2" in the Czech version

doi.org (Global: 2^nd place; Czech: 4^th place)

SAXTON, Robert A.; SABATINI, David M. mTOR Signaling in Growth, Metabolism, and Disease. Cell. 03 09, 2017, roč. 168, čís. 6, s. 960–976. PMID 28283069 PMCID: PMC5394987. Dostupné online [cit. 2020-02-16]. ISSN 1097-4172. doi:10.1016/j.cell.2017.02.004. PMID 28283069.

LAPLANTE, Mathieu; SABATINI, David M. mTOR signaling in growth control and disease. Cell. 2012-04-13, roč. 149, čís. 2, s. 274–293. PMID 22500797 PMCID: PMC3331679. Dostupné online [cit. 2020-02-16]. ISSN 1097-4172. doi:10.1016/j.cell.2012.03.017. PMID 22500797.

CHEN, Xizi; LIU, Mengjie; TIAN, Yuan. Cryo-EM structure of human mTOR complex 2. Cell Research. 2018-5, roč. 28, čís. 5, s. 518–528. PMID 29567957 PMCID: PMC5951902. Dostupné online [cit. 2020-02-16]. ISSN 1001-0602. doi:10.1038/s41422-018-0029-3. PMID 29567957.

MENDOZA, Michelle C.; ER, E. Emrah; BLENIS, John. The Ras-ERK and PI3K-mTOR Pathways: Cross-talk and Compensation. Trends in biochemical sciences. 2011-6, roč. 36, čís. 6, s. 320–328. PMID 21531565 PMCID: PMC3112285. Dostupné online [cit. 2020-02-16]. ISSN 0968-0004. doi:10.1016/j.tibs.2011.03.006. PMID 21531565.

HUANG, Kezhen; FINGAR, Diane C. Growing knowledge of the mTOR signaling network. Seminars in Cell & Developmental Biology. 2014-12, roč. 36, s. 79–90. PMID 25242279 PMCID: PMC4253687. Dostupné online [cit. 2020-02-16]. ISSN 1096-3634. doi:10.1016/j.semcdb.2014.09.011. PMID 25242279.

BETZ, Charles; STRACKA, Daniele; PRESCIANOTTO-BASCHONG, Cristina. Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology. Proceedings of the National Academy of Sciences of the United States of America. 2013-07-30, roč. 110, čís. 31, s. 12526–12534. PMID 23852728 PMCID: PMC3732980. Dostupné online [cit. 2020-02-16]. ISSN 1091-6490. doi:10.1073/pnas.1302455110. PMID 23852728.

SARBASSOV, D. D.; ALI, Siraj M.; KIM, Do-Hyung. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Current biology: CB. 2004-07-27, roč. 14, čís. 14, s. 1296–1302. PMID 15268862. Dostupné online [cit. 2020-02-16]. ISSN 0960-9822. doi:10.1016/j.cub.2004.06.054. PMID 15268862.

SARBASSOV, D. D.; GUERTIN, David A.; ALI, Siraj M. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science (New York, N.Y.). 2005-02-18, roč. 307, čís. 5712, s. 1098–1101. PMID 15718470. Dostupné online [cit. 2020-02-16]. ISSN 1095-9203. doi:10.1126/science.1106148. PMID 15718470.

STEPHENS, L.; ANDERSON, K.; STOKOE, D. Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science (New York, N.Y.). 1998-01-30, roč. 279, čís. 5351, s. 710–714. PMID 9445477. Dostupné online [cit. 2020-02-16]. ISSN 0036-8075. doi:10.1126/science.279.5351.710. PMID 9445477.

BEEVERS, Christopher S.; LI, Fengjun; LIU, Lei. Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells. International Journal of Cancer. 2006-08-15, roč. 119, čís. 4, s. 757–764. PMID 16550606. Dostupné online [cit. 2020-02-16]. ISSN 0020-7136. doi:10.1002/ijc.21932. PMID 16550606.

YANG, Zhifen; KLIONSKY, Daniel J. Mammalian autophagy: core molecular machinery and signaling regulation. Current Opinion in Cell Biology. 2010-04, roč. 22, čís. 2, s. 124–131. PMID 20034776 PMCID: PMC2854249. Dostupné online [cit. 2020-02-16]. ISSN 1879-0410. doi:10.1016/j.ceb.2009.11.014. PMID 20034776.

DATAN, Emmanuel; SHIRAZIAN, Alireza; BENJAMIN, Shawna. mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection. Virology. 2014-03, roč. 452-453, s. 175–190. PMID 24606695 PMCID: PMC4005847. Dostupné online [cit. 2020-02-16]. ISSN 1096-0341. doi:10.1016/j.virol.2014.01.008. PMID 24606695.

ARIAS, Esperanza; KOGA, Hiroshi; DIAZ, Antonio. Lysosomal mTORC2/PHLPP1/Akt Regulate Chaperone-Mediated Autophagy. Molecular Cell. 2015-07-16, roč. 59, čís. 2, s. 270–284. PMID 26118642 PMCID: PMC4506737. Dostupné online [cit. 2020-02-16]. ISSN 1097-4164. doi:10.1016/j.molcel.2015.05.030. PMID 26118642.

YIN, Yancun; HUA, Hui; LI, Minjing. mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR. Cell Research. 2016-01, roč. 26, čís. 1, s. 46–65. PMID 26584640 PMCID: PMC4816127. Dostupné online [cit. 2020-02-16]. ISSN 1748-7838. doi:10.1038/cr.2015.133. PMID 26584640.

ZONCU, Roberto; EFEYAN, Alejo; SABATINI, David M. mTOR: from growth signal integration to cancer, diabetes and ageing. Nature Reviews. Molecular Cell Biology. 2011-01, roč. 12, čís. 1, s. 21–35. PMID 21157483 PMCID: PMC3390257. Dostupné online [cit. 2020-02-16]. ISSN 1471-0080. doi:10.1038/nrm3025. PMID 21157483.

EBNER, Michael; SINKOVICS, Benjamin; SZCZYGIEŁ, Magdalena. Localization of mTORC2 activity inside cells. The Journal of Cell Biology. 2017-02, roč. 216, čís. 2, s. 343–353. PMID 28143890 PMCID: PMC5294791. Dostupné online [cit. 2020-02-16]. ISSN 1540-8140. doi:10.1083/jcb.201610060. PMID 28143890.

FRIAS, Maria A.; THOREEN, Carson C.; JAFFE, Jacob D. mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. Current biology: CB. 2006-09-19, roč. 16, čís. 18, s. 1865–1870. PMID 16919458. Dostupné online [cit. 2020-02-16]. ISSN 0960-9822. doi:10.1016/j.cub.2006.08.001. PMID 16919458.

SARBASSOV, Dos D.; ALI, Siraj M.; SENGUPTA, Shomit. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Molecular Cell. 2006-04-21, roč. 22, čís. 2, s. 159–168. PMID 16603397. Dostupné online [cit. 2020-02-16]. ISSN 1097-2765. doi:10.1016/j.molcel.2006.03.029. PMID 16603397.

GUERTIN, David A.; STEVENS, Deanna M.; SAITOH, Maki. mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice. Cancer Cell. 2009-02-03, roč. 15, čís. 2, s. 148–159. PMID 19185849 PMCID: PMC2701381. Dostupné online [cit. 2020-02-16]. ISSN 1878-3686. doi:10.1016/j.ccr.2008.12.017. PMID 19185849.

LAMMING, Dudley W.; YE, Lan; KATAJISTO, Pekka. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. Science (New York, N.y.). 2012-03-30, roč. 335, čís. 6076, s. 1638–1643. PMID 22461615 PMCID: PMC3324089. Dostupné online [cit. 2020-02-16]. ISSN 0036-8075. doi:10.1126/science.1215135. PMID 22461615.

LIU, Qingsong; CHANG, Jae Won; WANG, Jinhua. Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer. Journal of Medicinal Chemistry. 2010-10-14, roč. 53, čís. 19, s. 7146–7155. PMID 20860370 PMCID: PMC3893826. Dostupné online [cit. 2020-02-16]. ISSN 1520-4804. doi:10.1021/jm101144f. PMID 20860370.

LIU, Pengda; GAN, Wenjian; CHIN, Y. Rebecca. PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex. Cancer Discovery. 2015-11, roč. 5, čís. 11, s. 1194–1209. PMID 26293922 PMCID: PMC4631654. Dostupné online [cit. 2020-02-16]. ISSN 2159-8290. doi:10.1158/2159-8290.CD-15-0460. PMID 26293922.

YANG, Guang; MURASHIGE, Danielle S.; HUMPHREY, Sean J. A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation. Cell Reports. 2015-08-11, roč. 12, čís. 6, s. 937–943. PMID 26235620. Dostupné online [cit. 2020-02-16]. ISSN 2211-1247. doi:10.1016/j.celrep.2015.07.016. PMID 26235620.

HSU, Peggy P.; KANG, Seong A.; RAMESEDER, Jonathan. The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science (New York, N.Y.). 2011-06-10, roč. 332, čís. 6035, s. 1317–1322. PMID 21659604 PMCID: PMC3177140. Dostupné online [cit. 2020-02-16]. ISSN 1095-9203. doi:10.1126/science.1199498. PMID 21659604.

CHEN, Jianquan; HOLGUIN, Nilsson; SHI, Yu. mTORC2 signaling promotes skeletal growth and bone formation in mice. Journal of Bone and Mineral Research: The Official Journal of the American Society for Bone and Mineral Research. 2015-02, roč. 30, čís. 2, s. 369–378. PMID 25196701 PMCID: PMC4322759. Dostupné online [cit. 2020-02-16]. ISSN 1523-4681. doi:10.1002/jbmr.2348. PMID 25196701.

CAMERON, Angus J. M.; LINCH, Mark D.; SAURIN, Adrian T. mTORC2 targets AGC kinases through Sin1-dependent recruitment. The Biochemical Journal. 2011-10-15, roč. 439, čís. 2, s. 287–297. PMID 21806543. Dostupné online [cit. 2020-02-16]. ISSN 1470-8728. doi:10.1042/BJ20110678. PMID 21806543.

GAN, Xiaoqing; WANG, Jiyong; WANG, Chen. PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12. Nature Cell Biology. 2012-05-20, roč. 14, čís. 7, s. 686–696. PMID 22609986 PMCID: PMC3389271. Dostupné online [cit. 2020-02-16]. ISSN 1476-4679. doi:10.1038/ncb2507. PMID 22609986.

JHANWAR-UNIYAL, Meena; AMIN, Anubhav G.; COOPER, Jared B. Discrete signaling mechanisms of mTORC1 and mTORC2: Connected yet apart in cellular and molecular aspects. Advances in Biological Regulation. 05 2017, roč. 64, s. 39–48. PMID 28189457. Dostupné online [cit. 2020-02-16]. ISSN 2212-4934. doi:10.1016/j.jbior.2016.12.001. PMID 28189457.

LINKE, Monika; FRITSCH, Stephanie Deborah; SUKHBAATAR, Nyamdelger. mTORC1 and mTORC2 as regulators of cell metabolism in immunity. FEBS letters. 10 2017, roč. 591, čís. 19, s. 3089–3103. PMID 28600802 PMCID: PMC6322652. Dostupné online [cit. 2020-02-16]. ISSN 1873-3468. doi:10.1002/1873-3468.12711. PMID 28600802.

LUO, Yongting; XU, Wenyi; LI, Guannan. Weighing In on mTOR Complex 2 Signaling: The Expanding Role in Cell Metabolism. Oxidative Medicine and Cellular Longevity. 2018, roč. 2018, s. 7838647. PMID 30510625 PMCID: PMC6232796. Dostupné online [cit. 2020-02-16]. ISSN 1942-0994. doi:10.1155/2018/7838647. PMID 30510625.

GRABINER, Brian C.; NARDI, Valentina; BIRSOY, Kıvanc. A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity. Cancer Discovery. 2014-05, roč. 4, čís. 5, s. 554–563. PMID 24631838 PMCID: PMC4012430. Dostupné online [cit. 2020-02-16]. ISSN 2159-8290. doi:10.1158/2159-8290.CD-13-0929. PMID 24631838.

MASUI, Kenta; CAVENEE, Webster K.; MISCHEL, Paul S. mTORC2 in the center of cancer metabolic reprogramming. Trends in endocrinology and metabolism: TEM. 2014-07, roč. 25, čís. 7, s. 364–373. PMID 24856037 PMCID: PMC4077930. Dostupné online [cit. 2020-02-16]. ISSN 1879-3061. doi:10.1016/j.tem.2014.04.002. PMID 24856037.

GURI, Yakir; COLOMBI, Marco; DAZERT, Eva. mTORC2 Promotes Tumorigenesis via Lipid Synthesis. Cancer Cell. 2017-12-11, roč. 32, čís. 6, s. 807–823.e12. PMID 29232555. Dostupné online [cit. 2020-02-16]. ISSN 1878-3686. doi:10.1016/j.ccell.2017.11.011. PMID 29232555.

CHANG, Wenteh; WEI, Ke; HO, Lawrence. A critical role for the mTORC2 pathway in lung fibrosis. PloS One. 2014, roč. 9, čís. 8, s. e106155. PMID 25162417 PMCID: PMC4146613. Dostupné online [cit. 2020-02-16]. ISSN 1932-6203. doi:10.1371/journal.pone.0106155. PMID 25162417.

MONTEITH, Andrew J.; VINCENT, Heather A.; KANG, SunAh. mTORC2 Activity Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a. Journal of Immunology (Baltimore, Md.: 1950). 07 15, 2018, roč. 201, čís. 2, s. 371–382. PMID 29866702 PMCID: PMC6039264. Dostupné online [cit. 2020-02-16]. ISSN 1550-6606. doi:10.4049/jimmunol.1701712. PMID 29866702.

HAGIWARA, Asami; CORNU, Marion; CYBULSKI, Nadine. Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c. Cell Metabolism. 2012-05-02, roč. 15, čís. 5, s. 725–738. PMID 22521878. Dostupné online [cit. 2020-02-16]. ISSN 1932-7420. doi:10.1016/j.cmet.2012.03.015. PMID 22521878.

YUAN, Minsheng; PINO, Elizabeth; WU, Lianfeng. Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2. The Journal of Biological Chemistry. 2012-08-24, roč. 287, čís. 35, s. 29579–29588. PMID 22773877 PMCID: PMC3436168. Dostupné online [cit. 2020-02-16]. ISSN 1083-351X. doi:10.1074/jbc.M112.386854. PMID 22773877.

LAMMING, Dudley W.; DEMIRKAN, Gokhan; BOYLAN, Joan M. Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2). The FASEB Journal. 2014-1, roč. 28, čís. 1, s. 300–315. PMID 24072782 PMCID: PMC3868844. Dostupné online [cit. 2020-02-16]. ISSN 0892-6638. doi:10.1096/fj.13-237743. PMID 24072782.

LAMMING, Dudley W; MIHAYLOVA, Maria M; KATAJISTO, Pekka. Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan. Aging Cell. 2014-10, roč. 13, čís. 5, s. 911–917. PMID 25059582 PMCID: PMC4172536. Dostupné online [cit. 2020-02-16]. ISSN 1474-9718. doi:10.1111/acel.12256. PMID 25059582.

CYBULSKI, Nadine; POLAK, Pazit; AUWERX, Johan. mTOR complex 2 in adipose tissue negatively controls whole-body growth. Proceedings of the National Academy of Sciences of the United States of America. 2009-06-16, roč. 106, čís. 24, s. 9902–9907. PMID 19497867 PMCID: PMC2700987. Dostupné online [cit. 2020-02-16]. ISSN 1091-6490. doi:10.1073/pnas.0811321106. PMID 19497867.

KUMAR, Anil; LAWRENCE, John C.; JUNG, Dae Young. Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism. Diabetes. 2010-06, roč. 59, čís. 6, s. 1397–1406. PMID 20332342 PMCID: PMC2874700. Dostupné online [cit. 2020-02-16]. ISSN 1939-327X. doi:10.2337/db09-1061. PMID 20332342.

KUMAR, Anil; HARRIS, Thurl E.; KELLER, Susanna R. Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity. Molecular and Cellular Biology. 2008-01, roč. 28, čís. 1, s. 61–70. PMID 17967879 PMCID: PMC2223287. Dostupné online [cit. 2020-02-16]. ISSN 1098-5549. doi:10.1128/MCB.01405-07. PMID 17967879.

KLEINERT, Maximilian; SYLOW, Lykke; FAZAKERLEY, Daniel J. Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo. Molecular Metabolism. 2014-09, roč. 3, čís. 6, s. 630–641. PMID 25161886 PMCID: PMC4142396. Dostupné online [cit. 2020-02-16]. ISSN 2212-8778. doi:10.1016/j.molmet.2014.06.004. PMID 25161886.

GU, Yanyun; LINDNER, Jill; KUMAR, Anil. Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size. Diabetes. 2011-03, roč. 60, čís. 3, s. 827–837. PMID 21266327 PMCID: PMC3046843. Dostupné online [cit. 2020-02-16]. ISSN 1939-327X. doi:10.2337/db10-1194. PMID 21266327.

CHELLAPPA, Karthikeyani; BRINKMAN, Jacqueline A.; MUKHERJEE, Sarmistha. Hypothalamic mTORC2 is essential for metabolic health and longevity. Aging Cell. 2019-10, roč. 18, čís. 5, s. e13014. PMID 31373126 PMCID: PMC6718533. Dostupné online [cit. 2020-02-16]. ISSN 1474-9726. doi:10.1111/acel.13014. PMID 31373126.

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MTORC2 (Czech Wikipedia)

doi.org (Global: 2nd place; Czech: 4th place)

nih.gov (Global: 4th place; Czech: 8th place)

ncbi.nlm.nih.gov

worldcat.org (Global: 5th place; Czech: 3rd place)

doi.org (Global: 2^nd place; Czech: 4^th place)

nih.gov (Global: 4^th place; Czech: 8^th place)

worldcat.org (Global: 5^th place; Czech: 3^rd place)