Down syndrome (English Wikipedia)

Evans-Martin FF (2009). Down syndrome. New York: Chelsea House. p. 12. ISBN 978-1-4381-1950-2.
Margulies P (2007). Down syndrome (1st ed.). New York: Rosen Pub. Group. p. 5. ISBN 978-1-4042-0695-3.
Evans-Martin FF (2009). Down syndrome. New York: Chelsea House. p. 71. ISBN 978-1-4381-1950-2.
Evans-Martin FF (2009). Down Syndrome. New York: Chelsea House. pp. 13–14. ISBN 978-1-4381-1950-2.
Westman JS (2005). Medical genetics for the modern clinician. Philadelphia, PA: Lippincott Williams & Wilkins. p. 136. ISBN 978-0-7817-5760-7.

bbc.com

"Nikic becomes first person with Down's syndrome to finish Ironman". BBC Sport. Retrieved 2023-04-01.

books.google.com

Smith K (2011). The politics of Down syndrome. [New Alresford, Hampshire]: Zero. p. 3. ISBN 978-1-84694-613-4. Archived from the original on 2017-01-23.
Steinbock B (2011). "The Risk of Transmitting Disease or Disability". Life before birth the moral and legal status of embryos and fetuses (2nd ed.). Oxford: Oxford University Press. p. 222. ISBN 978-0-19-971207-6. Archived from the original on 2017-01-23.
Faragher R, Clarke B, eds. (2013). "Introduction". Educating Learners with Down Syndrome: Research, theory, and practice with children and adolescents. Taylor & Francis. p. 5. ISBN 978-1-134-67335-3. Archived from the original on 2017-01-23.
Johnston JM, Smyth MD, McKinstry RC (2008). "Basics of Neuroimaging in Pediatric Epilepsy". In Pellock JM, Bourgeois BF, Dodson WE, Nordli Jr DR, Sankar R (eds.). Pediatric epilepsy diagnosis and therapy (3rd ed.). New York: Demos Medical Pub. p. Chapter 67. ISBN 978-1-934559-86-4. Archived from the original on 2017-01-23.
Epstein CJ (2007). The consequences of chromosome imbalance: principles, mechanisms, and models. Cambridge: Cambridge University Press. pp. 255–256. ISBN 978-0-521-03809-6. Archived from the original on 2017-01-23.
Marion RW, Samanich JN (2012). "Genetics". In Bernstein D, Shelov SP (eds.). Pediatrics for medical students (3rd ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 259. ISBN 978-0-7817-7030-9. Archived from the original on 2017-01-23.
Bertoti DB, Smith DE (2008). "Mental Retardation: Focus on Down Syndrome". In Tecklin JS (ed.). Pediatric physical therapy (4th ed.). Philadelphia: Lippincott Williams & Wilkins. p. 380. ISBN 978-0-7817-5399-9. Archived from the original on 2017-01-23.
Domino FJ, ed. (2007). The 5-minute clinical consult 2007 (2007 ed.). Philadelphia: Lippincott Williams & Wilkins. p. 392. ISBN 978-0-7817-6334-9. Archived from the original on 2017-01-23.
Wilson GN, Cooley WC (2006). Preventive management of children with congenital anomalies and syndromes (2nd ed.). Cambridge: Cambridge University Press. p. 190. ISBN 978-0-521-61734-5. Archived from the original on 2017-01-23.
Williams Textbook of Endocrinology Expert Consult (12th ed.). London: Elsevier Health Sciences. 2011. ISBN 978-1-4377-3600-7. Archived from the original on 2017-01-23.
Batshaw M, ed. (2005). Children with disabilities (5th ed.). Baltimore [u.a.]: Paul H. Brookes. p. 308. ISBN 978-1-55766-581-2. Archived from the original on 2017-01-23.
Schwartz MW, ed. (2012). The 5-minute pediatric consult (6th ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 289. ISBN 978-1-4511-1656-4. Archived from the original on 2017-01-23.
Skoto BG, Roberts M (2024-02-28). "Down Syndrome". In Domino FJ (ed.). The 5-Minute Clinical Consult 2025. Lippincott Williams & Wilkins. ISBN 978-1-9752-3473-7.
Goldstein S, ed. (2011). Handbook of neurodevelopmental and genetic disorders in children (2nd ed.). New York: Guilford Press. p. 365. ISBN 978-1-60623-990-2. Archived from the original on 2017-01-23.
Prasher VP (2009). Neuropsychological assessments of dementia in Down syndrome and intellectual disabilities. London: Springer. p. 56. ISBN 978-1-84800-249-4. Archived from the original on 2017-01-23.
Urbano R (9 September 2010). Health Issues Among Persons With Down Syndrome. Academic Press. p. 129. ISBN 978-0-12-374477-7. Archived from the original on 12 May 2015.
Thomas-Tikhonenko A, ed. (2010). Cancer genome and tumor microenvironment (Online-Ausg. ed.). New York: Springer. p. 203. ISBN 978-1-4419-0711-0. Archived from the original on 2015-07-04.
Nelson MR (2011). Pediatrics. New York: Demos Medical. p. 88. ISBN 978-1-61705-004-6. Archived from the original on 2017-01-23.
Reisner H (2013). Essentials of Rubin's Pathology. Lippincott Williams & Wilkins. pp. 129–131. ISBN 978-1-4511-8132-6. Archived from the original on 2017-01-23.
Mandal K (2013). Treatment & prognosis in pediatrics. Jaypee Brothers Medical P. p. 391. ISBN 978-93-5090-428-2. Archived from the original on 2017-01-23.
Fletcher-Janzen E, Reynolds CR (2007). Encyclopedia of special education: a reference for the education of children, adolescents, and adults with disabilities and other exceptional individuals (3rd ed.). New York: John Wiley & Sons. p. 458. ISBN 978-0-470-17419-7. Archived from the original on 2017-01-23.
Zhang DY, Cheng L (2008). Molecular genetic pathology. Totowa, N.J.: Humana. p. 45. ISBN 978-1-59745-405-6. Archived from the original on 2017-01-23.
David AK (2013). Family Medicine Principles and Practice (Sixth ed.). New York, NY: Springer New York. p. 142. ISBN 978-0-387-21744-4. Archived from the original on 2017-01-23.
Cummings M (2013). Human Heredity: Principles and Issues (10th ed.). Cengage Learning. p. 138. ISBN 978-1-285-52847-2. Archived from the original on 2017-01-23.
Strauss JF, Barbieri RL (2009). Yen and Jaffe's reproductive endocrinology: physiology, pathophysiology, and clinical management (6th ed.). Philadelphia, PA: Saunders/Elsevier. p. 791. ISBN 978-1-4160-4907-4. Archived from the original on 2017-01-23.
Menkes JH, Sarnat HB (2005). Child neurology (7th ed.). Philadelphia, PA: Lippincott Williams & Wilkins. p. 228. ISBN 978-0-7817-5104-9. Archived from the original on 2017-01-23.
Gardner RJ, Sutherland GR, Shaffer LG, eds. (2012). Chromosome abnormalities and genetic counseling (4th ed.). Oxford: Oxford University Press. p. 292. ISBN 978-0-19-974915-7. Archived from the original on 2017-01-23.
New RS, Cochran M (2007). Early childhood education an international encyclopedia. Westport, Conn.: Praeger Publishers. p. 305. ISBN 978-0-313-01448-2. Archived from the original on 2017-01-23.
Urbano R (9 September 2010). Health Issues Among Persons With Down Syndrome. Academic Press. p. 108. ISBN 978-0-12-374477-7. Archived from the original on 12 May 2015.
Fisch H (2013). "The male biological clock". In Carrell DT (ed.). Paternal influences on human reproductive success. Cambridge University Press. p. 65. ISBN 978-1-107-02448-9. Archived from the original on 2017-01-23.
Evans-Martin FF (2009). Down Syndrome. Genes & Disease. New York: Infobase Publishing. p. 13. ISBN 9781438119502. Retrieved 20 March 2020. There is also very little representation of Down syndrome in art over the centuries. Only a few paintings, such as the sixteenth century Flemish painting The Adoration of the Christ Child, have been identified in which characters appear to have facial features and other characteristics typical of Down syndrome.
Wright D (25 August 2011). Downs: The history of a disability. Oxford University Press. pp. 104–108. ISBN 978-0-19-956793-5. Archived from the original on 28 May 2013. Retrieved 25 August 2012.
Wright D (25 August 2011). Downs: The history of a disability. Oxford University Press. p. 145. ISBN 978-0-19-956793-5. Archived from the original on 28 May 2013. Retrieved 25 August 2012.
Wright D (25 August 2011). Downs: The history of a disability. Oxford University Press. pp. 9–10. ISBN 978-0-19-956793-5. Archived from the original on 28 May 2013. Retrieved 25 August 2012.
Leonard BJ, Crainshaw JY (2013). Encyclopedia of religious controversies in the United States (2nd ed.). Santa Barbara, Calif.: ABC-CLIO. p. 278. ISBN 978-1-59884-867-0. Archived from the original on 2017-01-23.
Shields SG, Candib LM (2010). Woman-centered care in pregnancy and childbirth. Oxford: Radcliffe Pub. p. 140. ISBN 978-1-84619-161-9. Archived from the original on 2017-01-23.
Wright D (2011). "Into the Mainstream". Downs: The history of a disability. Oxford University Press. p. 147. ISBN 978-0-19-161978-6. Archived from the original on 2017-01-23.
Pratt G, Rosner V (2012). The global and the intimate feminism in our time. New York: Columbia University Press. p. 113. ISBN 978-0-231-52084-3. Archived from the original on 2017-01-23.

buzzfeednews.com

Probus S, McNeal J (12 February 2015). "Meet The First Woman With Down Syndrome To Walk At Fashion Week". BuzzFeed News. Retrieved 2023-04-01.

cambscommunityservices.nhs.uk

"Early Development for Children with Down Syndrome". INHS Cambridgeshire Community Services NHS Trust. Retrieved 28 March 2023.

cardiosmart.org

"Survival Rates Improving for Patients with Down Syndrome and Congenital Heart Defects". CardioSmart. Retrieved 2023-03-31.

cbc.ca

"Halifax mom questions Down syndrome suppression". Archived from the original on 2015-11-05. Retrieved 2015-09-26.

cdc.gov

"Facts about Down Syndrome | CDC". Centers for Disease Control and Prevention. 2021-04-06. Retrieved 2023-03-31.
"Birth Defects, Down Syndrome". National Center on Birth Defects and Developmental Disabilities. US: Centers for Disease Control and Prevention. 2013-11-06. Archived from the original on 2017-07-28.

channelkindness.org

Strobel G (2020-01-24). "#TheGraceEffect – Creating Ripples With Kindness And Respect". Channel Kindness. Retrieved 2023-04-01.

childrenshospital.org

"Strabismus and Amblyopia | Boston Children's Hospital". www.childrenshospital.org. Retrieved 2024-05-08.

chrisnikic.com

"About – Chris Nikic". chrisnikic.com. Retrieved 2023-04-01.

disabilityscoop.com

Heasley S (2015-11-16). "New TV Series Features Young Adults With Down Syndrome". Disability Scoop. Retrieved 2023-04-01.

doi.org

Weijerman ME, de Winter JP (December 2010). "Clinical practice. The care of children with Down syndrome". European Journal of Pediatrics. 169 (12): 1445–1452. doi:10.1007/s00431-010-1253-0. PMC 2962780. PMID 20632187.
Patterson D (July 2009). "Molecular genetic analysis of Down syndrome". Human Genetics. 126 (1): 195–214. doi:10.1007/s00439-009-0696-8. ISSN 0340-6717. PMID 19526251. S2CID 10403507.
Morris JK, Mutton DE, Alberman E (2002). "Revised estimates of the maternal age specific live birth prevalence of Down's syndrome". Journal of Medical Screening. 9 (1): 2–6. doi:10.1136/jms.9.1.2. PMID 11943789.
Roizen NJ, Patterson D (April 2003). "Down's syndrome". Lancet (Review). 361 (9365): 1281–1289. doi:10.1016/S0140-6736(03)12987-X. PMID 12699967. S2CID 33257578.
Malt EA, Dahl RC, Haugsand TM, Ulvestad IH, Emilsen NM, Hansen B, et al. (February 2013). "Health and disease in adults with Down syndrome". Tidsskrift for den Norske Laegeforening. 133 (3): 290–294. doi:10.4045/tidsskr.12.0390. PMID 23381164.
GBD 2015 Disease and Injury Incidence and Prevalence Collaborators (October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282.
Seror V, L'Haridon O, Bussières L, Malan V, Fries N, Vekemans M, et al. (March 2019). "Women's Attitudes Toward Invasive and Noninvasive Testing When Facing a High Risk of Fetal Down Syndrome". JAMA Network Open. 2 (3): e191062. doi:10.1001/jamanetworkopen.2019.1062. PMC 6450316. PMID 30924894.
Natoli JL, Ackerman DL, McDermott S, Edwards JG (February 2012). "Prenatal diagnosis of Down syndrome: a systematic review of termination rates (1995-2011)". Prenatal Diagnosis. 32 (2): 142–153. doi:10.1002/pd.2910. PMID 22418958.
Mansfield C, Hopfer S, Marteau TM (September 1999). "Termination rates after prenatal diagnosis of Down syndrome, spina bifida, anencephaly, and Turner and Klinefelter syndromes: a systematic literature review. European Concerted Action: DADA (Decision-making After the Diagnosis of a fetal Abnormality)". Prenatal Diagnosis. 19 (9). Wiley: 808–812. doi:10.1002/(sici)1097-0223(199909)19:9<808::aid-pd637>3.0.co;2-b. PMID 10521836. S2CID 29637272.
Martínez-Espinosa RM, Molina Vila MD, Reig García-Galbis M (June 2020). "Evidences from Clinical Trials in Down Syndrome: Diet, Exercise and Body Composition". International Journal of Environmental Research and Public Health. 17 (12): 4294. doi:10.3390/ijerph17124294. PMC 7344556. PMID 32560141.
GBD 2015 Mortality and Causes of Death Collaborators (October 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/s0140-6736(16)31012-1. PMC 5388903. PMID 27733281.
GBD 2013 Mortality and Causes of Death Collaborators (January 2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013". Lancet. 385 (9963): 117–171. doi:10.1016/S0140-6736(14)61682-2. PMC 4340604. PMID 25530442.
Hickey F, Hickey E, Summar KL (2012). "Medical update for children with Down syndrome for the pediatrician and family practitioner". Advances in Pediatrics. 59 (1). Elsevier BV: 137–157. doi:10.1016/j.yapd.2012.04.006. PMID 22789577.
Hippolyte L, Iglesias K, Van der Linden M, Barisnikov K (August 2010). "Social reasoning skills in adults with Down syndrome: the role of language, executive functions and socio-emotional behaviour". Journal of Intellectual Disability Research. 54 (8): 714–726. doi:10.1111/j.1365-2788.2010.01299.x. PMID 20590998.
Perkins JA (December 2009). "Overview of macroglossia and its treatment". Current Opinion in Otolaryngology & Head and Neck Surgery. 17 (6): 460–465. doi:10.1097/moo.0b013e3283317f89. PMID 19713845. S2CID 45941755.
Bull MJ, Trotter T, Santoro SL, Christensen C, Grout RW, Burke LW, et al. (Council on Genetics) (May 2022). "Health Supervision for Children and Adolescents With Down Syndrome". Pediatrics. 149 (5). doi:10.1542/peds.2022-057010. PMID 35490285. S2CID 248252638.
Bull MJ (June 2020). "Down Syndrome". The New England Journal of Medicine. 382 (24): 2344–2352. doi:10.1056/NEJMra1706537. PMID 32521135. S2CID 219586275.
Pierce M, Ramsey K, Pinter J (2 April 2019). "Trends in Obesity and Overweight in Oregon Children With Down Syndrome". Global Pediatric Health. 6: 2333794X19835640. doi:10.1177/2333794X19835640. PMC 6446252. PMID 31044152.
Winders P, Wolter-Warmerdam K, Hickey F (April 2019). "A schedule of gross motor development for children with Down syndrome". Journal of Intellectual Disability Research. 63 (4): 346–356. doi:10.1111/jir.12580. PMID 30575169. S2CID 58592265.
Reilly C (October 2012). "Behavioural phenotypes and special educational needs: is aetiology important in the classroom?". Journal of Intellectual Disability Research. 56 (10): 929–946. doi:10.1111/j.1365-2788.2012.01542.x. PMID 22471356.
Patterson T, Rapsey CM, Glue P (April 2013). "Systematic review of cognitive development across childhood in Down syndrome: implications for treatment interventions". Journal of Intellectual Disability Research. 57 (4): 306–318. doi:10.1111/j.1365-2788.2012.01536.x. PMID 23506141.
Windsperger K, Hoehl S (2021). "Development of Down Syndrome Research Over the Last Decades-What Healthcare and Education Professionals Need to Know". Frontiers in Psychiatry. 12: 749046. doi:10.3389/fpsyt.2021.749046. PMC 8712441. PMID 34970162.
Kent RD, Vorperian HK (February 2013). "Speech impairment in Down syndrome: a review". Journal of Speech, Language, and Hearing Research. 56 (1): 178–210. doi:10.1044/1092-4388(2012/12-0148). PMC 3584188. PMID 23275397.
Santoro JD, Filipink RA, Baumer NT, Bulova PD, Handen BL (2023-03-01). "Down syndrome regression disorder: updates and therapeutic advances". Current Opinion in Psychiatry. 36 (2): 96–103. doi:10.1097/YCO.0000000000000845. ISSN 1473-6578. PMID 36705008.
Weijerman ME, de Winter JP (December 2010). "Clinical practice. The care of children with Down syndrome". European Journal of Pediatrics. 169 (12): 1445–1452. doi:10.1007/s00431-010-1253-0. PMC 2962780. PMID 20632187.
Bull MJ, Trotter T, Santoro SL, Christensen C, Grout RW, THE COUNCIL ON GENETICS (2022-05-01). "Health Supervision for Children and Adolescents With Down Syndrome". Pediatrics. 149 (5). doi:10.1542/peds.2022-057010. ISSN 0031-4005. PMID 35490285.
Rodman R, Pine HS (June 2012). "The otolaryngologist's approach to the patient with Down syndrome". Otolaryngologic Clinics of North America. 45 (3): 599–629, vii–viii. doi:10.1016/j.otc.2012.03.010. PMID 22588039.
Bush D, Galambos C, Dunbar Ivy D (March 2021). "Pulmonary hypertension in children with Down syndrome". Pediatric Pulmonology. 56 (3): 621–629. doi:10.1002/ppul.24687. PMID 32049444. S2CID 211087826.
Nixon DW (March 2018). "Down Syndrome, Obesity, Alzheimer's Disease, and Cancer: A Brief Review and Hypothesis". Brain Sciences. 8 (4): 53. doi:10.3390/brainsci8040053. PMC 5924389. PMID 29587359.
Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A, et al. (July 2009). "The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes". Blood. 114 (5): 937–951. doi:10.1182/blood-2009-03-209262. PMID 19357394.
Seewald L, Taub JW, Maloney KW, McCabe ER (September 2012). "Acute leukemias in children with Down syndrome". Molecular Genetics and Metabolism. 107 (1–2): 25–30. doi:10.1016/j.ymgme.2012.07.011. PMID 22867885.
Lee P, Bhansali R, Izraeli S, Hijiya N, Crispino JD (September 2016). "The biology, pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with Down syndrome". Leukemia. 30 (9): 1816–1823. doi:10.1038/leu.2016.164. PMC 5434972. PMID 27285583.
Li J, Kalev-Zylinska ML (2022). "Advances in molecular characterization of myeloid proliferations associated with Down syndrome". Frontiers in Genetics. 13: 891214. doi:10.3389/fgene.2022.891214. PMC 9399805. PMID 36035173.
Gupte A, Al-Antary ET, Edwards H, Ravindranath Y, Ge Y, Taub JW (July 2022). "The paradox of Myeloid Leukemia associated with Down syndrome". Biochemical Pharmacology. 201: 115046. doi:10.1016/j.bcp.2022.115046. PMID 35483417. S2CID 248431139.
Tamblyn JA, Norton A, Spurgeon L, Donovan V, Bedford Russell A, Bonnici J, et al. (January 2016). "Prenatal therapy in transient abnormal myelopoiesis: a systematic review". Archives of Disease in Childhood. Fetal and Neonatal Edition. 101 (1): F67–F71. doi:10.1136/archdischild-2014-308004. PMID 25956670. S2CID 5958598.
Bhatnagar N, Nizery L, Tunstall O, Vyas P, Roberts I (October 2016). "Transient Abnormal Myelopoiesis and AML in Down Syndrome: an Update". Current Hematologic Malignancy Reports. 11 (5): 333–341. doi:10.1007/s11899-016-0338-x. PMC 5031718. PMID 27510823.
Gamis AS, Smith FO (November 2012). "Transient myeloproliferative disorder in children with Down syndrome: clarity to this enigmatic disorder". British Journal of Haematology. 159 (3): 277–287. doi:10.1111/bjh.12041. PMID 22966823. S2CID 37593917.
Graber E, Chacko E, Regelmann MO, Costin G, Rapaport R (December 2012). "Down syndrome and thyroid function". Endocrinology and Metabolism Clinics of North America. 41 (4): 735–745. doi:10.1016/j.ecl.2012.08.008. PMID 23099267.
Moore SW (August 2008). "Down syndrome and the enteric nervous system". Pediatric Surgery International. 24 (8): 873–883. doi:10.1007/s00383-008-2188-7. PMID 18633623. S2CID 11890549.
Bell J, Civil CR, Townsend GC, Brown RH (December 1989). "The prevalence of taurodontism in Down's syndrome". Journal of Mental Deficiency Research. 33 (6): 467–476. doi:10.1111/j.1365-2788.1989.tb01502.x. PMID 2533267.
Pradhan M, Dalal A, Khan F, Agrawal S (December 2006). "Fertility in men with Down syndrome: a case report". Fertility and Sterility. 86 (6): 1765.e1–1765.e3. doi:10.1016/j.fertnstert.2006.03.071. PMID 17094988. S2CID 32384231.
Ramasamy R, Chiba K, Butler P, Lamb DJ (June 2015). "Male biological clock: a critical analysis of advanced paternal age". Fertility and Sterility. 103 (6): 1402–1406. doi:10.1016/j.fertnstert.2015.03.011. PMC 4955707. PMID 25881878.
Lana-Elola E, Watson-Scales SD, Fisher EM, Tybulewicz VL (September 2011). "Down syndrome: searching for the genetic culprits". Disease Models & Mechanisms. 4 (5): 586–595. doi:10.1242/dmm.008078. PMC 3180222. PMID 21878459.
Patterson D, Cabelof DC (April 2012). "Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging". Mechanisms of Ageing and Development. 133 (4): 133–137. doi:10.1016/j.mad.2011.10.001. PMID 22019846. S2CID 3663890.
Weksler ME, Szabo P, Relkin NR, Reidenberg MM, Weksler BB, Coppus AM (April 2013). "Alzheimer's disease and Down's syndrome: treating two paths to dementia". Autoimmunity Reviews. 12 (6): 670–673. doi:10.1016/j.autrev.2012.10.013. PMID 23201920.
Horvath S, Garagnani P, Bacalini MG, Pirazzini C, Salvioli S, Gentilini D, et al. (June 2015). "Accelerated epigenetic aging in Down syndrome". Aging Cell. 14 (3): 491–495. doi:10.1111/acel.12325. PMC 4406678. PMID 25678027.
ACOG Committee on Practice Bulletins (January 2007). "ACOG Practice Bulletin No. 77: screening for fetal chromosomal abnormalities". Obstetrics and Gynecology. 109 (1): 217–227. doi:10.1097/00006250-200701000-00054. PMID 17197615.
Agathokleous M, Chaveeva P, Poon LC, Kosinski P, Nicolaides KH (March 2013). "Meta-analysis of second-trimester markers for trisomy 21". Ultrasound in Obstetrics & Gynecology. 41 (3): 247–261. doi:10.1002/uog.12364. PMID 23208748.
Malone FD, D'Alton ME (November 2003). "First-trimester sonographic screening for Down syndrome". Obstetrics and Gynecology. 102 (5 Pt 1): 1066–1079. doi:10.1016/j.obstetgynecol.2003.08.004. PMID 14672489. S2CID 24592539.
Canick J (June 2012). "Prenatal screening for trisomy 21: recent advances and guidelines". Clinical Chemistry and Laboratory Medicine. 50 (6): 1003–1008. doi:10.1515/cclm.2011.671. PMID 21790505. S2CID 37417471.
Alldred SK, Deeks JJ, Guo B, Neilson JP, Alfirevic Z (June 2012). "Second trimester serum tests for Down's Syndrome screening" (PDF). The Cochrane Database of Systematic Reviews. 2012 (6): CD009925. doi:10.1002/14651858.CD009925. PMC 7086392. PMID 22696388. Archived from the original (PDF) on December 9, 2019. Retrieved January 7, 2019.
Mersy E, Smits LJ, van Winden LA, de Die-Smulders CE, Paulussen AD, Macville MV, et al. (Jul–Aug 2013). "Noninvasive detection of fetal trisomy 21: systematic review and report of quality and outcomes of diagnostic accuracy studies performed between 1997 and 2012". Human Reproduction Update. 19 (4): 318–329. doi:10.1093/humupd/dmt001. PMID 23396607.
Verweij EJ, van den Oever JM, de Boer MA, Boon EM, Oepkes D (2012). "Diagnostic accuracy of noninvasive detection of fetal trisomy 21 in maternal blood: a systematic review". Fetal Diagnosis and Therapy. 31 (2): 81–86. doi:10.1159/000333060. PMID 22094923.
Benn P, Borrell A, Cuckle H, Dugoff L, Gross S, Johnson JA, et al. (January 2012). "Prenatal Detection of Down Syndrome using Massively Parallel Sequencing (MPS): a rapid response statement from a committee on behalf of the Board of the International Society for Prenatal Diagnosis, 24 October 2011" (PDF). Prenatal Diagnosis. 32 (1): 1–2. doi:10.1002/pd.2919. PMID 22275335. S2CID 42116198. Archived from the original (PDF) on 2012-03-19.
Bianchi DW, Parker RL, Wentworth J, Madankumar R, Saffer C, Das AF, et al. (February 2014). "DNA sequencing versus standard prenatal aneuploidy screening". The New England Journal of Medicine. 370 (9): 799–808. doi:10.1056/nejmoa1311037. PMID 24571752.
Tabor A, Alfirevic Z (2010). "Update on procedure-related risks for prenatal diagnosis techniques". Fetal Diagnosis and Therapy. 27 (1): 1–7. doi:10.1159/000271995. OCLC 23338607. PMID 20051662.
Choi H, Van Riper M, Thoyre S (Mar–Apr 2012). "Decision making following a prenatal diagnosis of Down syndrome: an integrative review". Journal of Midwifery & Women's Health. 57 (2): 156–164. doi:10.1111/j.1542-2011.2011.00109.x. PMID 22432488.
Bull MJ (August 2011). "Health supervision for children with Down syndrome". Pediatrics. 128 (2): 393–406. doi:10.1542/peds.2011-1605. PMID 21788214.
Roberts JE, Price J, Malkin C (2007). "Language and communication development in Down syndrome". Mental Retardation and Developmental Disabilities Research Reviews. 13 (1): 26–35. doi:10.1002/mrdd.20136. PMID 17326116.
Mohan M, Bennett C, Carpenter PK (January 2009). "Memantine for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007657. doi:10.1002/14651858.CD007657. PMC 7197456. PMID 19160343.
Mohan M, Carpenter PK, Bennett C (January 2009). "Donepezil for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007178. doi:10.1002/14651858.CD007178.pub2. PMC 7208846. PMID 19160328.
Mohan M, Bennett C, Carpenter PK (January 2009). "Rivastigmine for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007658. doi:10.1002/14651858.CD007658. PMC 7197503. PMID 19160344.
Mohan M, Bennett C, Carpenter PK (January 2009). "Galantamine for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007656. doi:10.1002/14651858.CD007656. PMC 7197502. PMID 19160342.
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. (December 2012). "Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010". Lancet. 380 (9859): 2095–2128. doi:10.1016/S0140-6736(12)61728-0. hdl:10536/DRO/DU:30050819. PMC 10790329. PMID 23245604. S2CID 1541253.
Parker SE, Mai CT, Canfield MA, Rickard R, Wang Y, Meyer RE, et al. (December 2010). "Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004-2006". Birth Defects Research. Part A, Clinical and Molecular Teratology. 88 (12): 1008–1016. doi:10.1002/bdra.20735. PMID 20878909.
Levitas AS, Reid CS (February 2003). "An angel with Down syndrome in a sixteenth century Flemish Nativity painting". American Journal of Medical Genetics. Part A. 116A (4): 399–405. doi:10.1002/ajmg.a.10043. PMID 12522800. S2CID 8821338. We have identified a 16th-century Flemish Nativity painting in which one angelic figure appears distinctly different from other individuals in the painting with an appearance of Down syndrome.
Neri G, Opitz JM (December 2009). "Down syndrome: comments and reflections on the 50th anniversary of Lejeune's discovery". American Journal of Medical Genetics. Part A. 149A (12): 2647–2654. doi:10.1002/ajmg.a.33138. PMID 19921741. S2CID 12945876.
Rodríguez-Hernández ML, Montoya E (July 2011). "Fifty years of evolution of the term Down's syndrome". Lancet. 378 (9789): 402. doi:10.1016/s0140-6736(11)61212-9. PMID 21803206. S2CID 8541289.
Howard-Jones N (January 1979). "On the diagnostic term "Down's disease"". Medical History. 23 (1): 102–4. doi:10.1017/s0025727300051048. PMC 1082401. PMID 153994.
Bernal JE, Briceno I (September 2006). "Genetic and other diseases in the pottery of Tumaco-La Tolita culture in Colombia-Ecuador". Clinical Genetics. 70 (3): 188–191. doi:10.1111/j.1399-0004.2006.00670.x. PMID 16922718. S2CID 27716271.
Gautier M, Harper PS (2009). "Fiftieth anniversary of trisomy 21: returning to a discovery" (PDF). Human Genetics. 126 (2): 317–324. doi:10.1007/s00439-009-0690-1. S2CID 30299551. Archived (PDF) from the original on 2017-02-02.
Pain E (February 2014). "History of science. After more than 50 years, a dispute over Down syndrome discovery". Science. 343 (6172): 720–721. Bibcode:2014Sci...343..720P. doi:10.1126/science.343.6172.720. PMID 24531949.
"Classification and nomenclature of morphological defects". Lancet. 1 (7905): 513. March 1975. doi:10.1016/S0140-6736(75)92847-0. PMID 46972. S2CID 37636187.
Chervenak FA, McCullough LB (April 2010). "Ethical considerations in first-trimester Down syndrome risk assessment". Current Opinion in Obstetrics & Gynecology. 22 (2): 135–138. doi:10.1097/gco.0b013e3283374a9f. PMID 20125014. S2CID 2017130.
Ravitsky V, Roy MC, Haidar H, Henneman L, Marshall J, Newson AJ, Ngan OM, Nov-Klaiman T (2021-08-31). "The Emergence and Global Spread of Noninvasive Prenatal Testing". Annual Review of Genomics and Human Genetics. 22 (1): 309–338. doi:10.1146/annurev-genom-083118-015053. ISSN 1527-8204. PMID 33848430.
Sharma G, McCullough LB, Chervenak FA (February 2007). "Ethical considerations of early (first vs. second trimester) risk assessment disclosure for trisomy 21 and patient choice in screening versus diagnostic testing". American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 145C (1): 99–104. doi:10.1002/ajmg.c.30118. PMID 17299736.
Savulescu J, Kahane G (June 2009). "The moral obligation to create children with the best chance of the best life". Bioethics. 23 (5): 274–290. doi:10.1111/j.1467-8519.2008.00687.x. PMID 19076124. S2CID 13897639.
Bennett R (June 2009). "The fallacy of the Principle of Procreative Beneficence". Bioethics. 23 (5): 265–273. doi:10.1111/j.1467-8519.2008.00655.x. PMID 18477055. S2CID 7373407.
Parens E, Asch A (2003). "Disability rights critique of prenatal genetic testing: reflections and recommendations". Mental Retardation and Developmental Disabilities Research Reviews. 9 (1): 40–47. doi:10.1002/mrdd.10056. PMID 12587137.
Green RM (Spring 1997). "Parental autonomy and the obligation not to harm one's child genetically". The Journal of Law, Medicine & Ethics. 25 (1): 5–15, 2. doi:10.1111/j.1748-720x.1997.tb01389.x. PMID 11066476. S2CID 38939256.
Briggs JA, Mason EA, Ovchinnikov DA, Wells CA, Wolvetang EJ (March 2013). "Concise review: new paradigms for Down syndrome research using induced pluripotent stem cells: tackling complex human genetic disease". Stem Cells Translational Medicine. 2 (3): 175–184. doi:10.5966/sctm.2012-0117. PMC 3659762. PMID 23413375.
Goodman MJ, Brixner DI (April 2013). "New therapies for treating Down syndrome require quality of life measurement". American Journal of Medical Genetics. Part A. 161A (4): 639–641. doi:10.1002/ajmg.a.35705. PMID 23495233. S2CID 43840950.
Mole B (2013). "Researchers turn off Down's syndrome genes". Nature News. doi:10.1038/nature.2013.13406. S2CID 87422171. Retrieved 25 December 2018.
Fillat C, Altafaj X (2012). "Gene therapy for Down syndrome". Down Syndrome: From Understanding the Neurobiology to Therapy. Progress in Brain Research. Vol. 197. pp. 237–47. doi:10.1016/B978-0-444-54299-1.00012-1. ISBN 9780444542991. PMID 22541296.
Costa AC, Scott-McKean JJ (September 2013). "Prospects for improving brain function in individuals with Down syndrome". CNS Drugs. 27 (9): 679–702. doi:10.1007/s40263-013-0089-3. PMID 23821040. S2CID 24030020.
Costa AC (2011). "On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of Down syndrome". Developmental Neuroscience. 33 (5): 414–427. doi:10.1159/000330861. PMC 3254040. PMID 21893967.
Sansom C (October 2015). "The evolution of human chromosome 2" (PDF). The Biochemist. 37 (5): 40–41. doi:10.1042/BIO03705040.
Hirata S, Hirai H, Nogami E, Morimura N, Udono T (April 2017). "Chimpanzee Down syndrome: a case study of trisomy 22 in a captive chimpanzee". Primates; Journal of Primatology. 58 (2). Springer: 267–273. doi:10.1007/s10329-017-0597-8. eISSN 1610-7365. hdl:2433/228259. LCCN sf80001417. OCLC 51531954. PMID 28220267. S2CID 5536021.
Conde-Valverde M, Quirós-Sánchez A, Diez-Valero J, Mata-Castro N, García-Fernández A, Quam R, Carretero JM, García-González R, Rodríguez L, Sánchez-Andrés Á, Arsuaga JL, Martínez I, Villaverde V (2024). "The child who lived: Down syndrome among Neanderthals?". Science Advances. 10 (26): eadn9310. Bibcode:2024SciA...10N9310C. doi:10.1126/sciadv.adn9310. PMC 11204207. PMID 38924400.

down-syndrome.eu

"European Down Syndrome Association news" (PDF). European Down Syndrome Association. 2006. Archived from the original (PDF) on 22 February 2014. Retrieved 7 February 2014.

ds-int.org

"World Down Syndrome Day". Down Syndrome International. Archived from the original on 14 March 2014. Retrieved 2 February 2014.

dseinternational.org

"Development and learning for people with Down syndrome". Archived from the original on 2016-11-19. Retrieved 2016-11-18.

dsiso.org

Emily Laurence. "Paralympics Participation swimmers with Down syndrome". Down Syndrome International Swimming Organisation. Retrieved March 2, 2024.

ed.gov

nces.ed.gov

"Number of 14- through 21-year-old students served under Individuals with Disabilities Education Act, Part B, who exited school, by exit reason, age, and type of disability: 2007–08 and 2008–09". National Center for Education Statistics. Archived from the original on 22 February 2014. Retrieved 7 February 2014.

emmys.com

"Born This Way". Television Academy. Retrieved 2023-04-01.

escholarship.org

Mansfield C, Hopfer S, Marteau TM (September 1999). "Termination rates after prenatal diagnosis of Down syndrome, spina bifida, anencephaly, and Turner and Klinefelter syndromes: a systematic literature review. European Concerted Action: DADA (Decision-making After the Diagnosis of a fetal Abnormality)". Prenatal Diagnosis. 19 (9). Wiley: 808–812. doi:10.1002/(sici)1097-0223(199909)19:9<808::aid-pd637>3.0.co;2-b. PMID 10521836. S2CID 29637272.

espn.com

"2021 ESPYS award winners". ESPN.com. 2021-07-10. Retrieved 2023-04-01.

eyewiki.org

"Trisomy 21/Down Syndrome - EyeWiki". eyewiki.org. Retrieved 2024-05-07.

globaldownsyndrome.org

"National Down Syndrome Organizations in the U.S." Global Down Syndrome Foundation. 2012-02-21. Archived from the original on 18 January 2014. Retrieved 2 February 2014.

handle.net

hdl.handle.net

Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. (December 2012). "Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010". Lancet. 380 (9859): 2095–2128. doi:10.1016/S0140-6736(12)61728-0. hdl:10536/DRO/DU:30050819. PMC 10790329. PMID 23245604. S2CID 1541253.
Hirata S, Hirai H, Nogami E, Morimura N, Udono T (April 2017). "Chimpanzee Down syndrome: a case study of trisomy 22 in a captive chimpanzee". Primates; Journal of Primatology. 58 (2). Springer: 267–273. doi:10.1007/s10329-017-0597-8. eISSN 1610-7365. hdl:2433/228259. LCCN sf80001417. OCLC 51531954. PMID 28220267. S2CID 5536021.

harvard.edu

ui.adsabs.harvard.edu

Pain E (February 2014). "History of science. After more than 50 years, a dispute over Down syndrome discovery". Science. 343 (6172): 720–721. Bibcode:2014Sci...343..720P. doi:10.1126/science.343.6172.720. PMID 24531949.
Conde-Valverde M, Quirós-Sánchez A, Diez-Valero J, Mata-Castro N, García-Fernández A, Quam R, Carretero JM, García-González R, Rodríguez L, Sánchez-Andrés Á, Arsuaga JL, Martínez I, Villaverde V (2024). "The child who lived: Down syndrome among Neanderthals?". Science Advances. 10 (26): eadn9310. Bibcode:2024SciA...10N9310C. doi:10.1126/sciadv.adn9310. PMC 11204207. PMID 38924400.

hola.com

"Puerto Rican model with Down Syndrome, Sofía Jirau is conquering the fashion world". HOLA. 2020-02-19. Retrieved 2023-04-01.

hopkinsmedicine.org

"Keratoconus". www.hopkinsmedicine.org. 2021-08-08. Retrieved 2024-05-08.
Gautier M, Harper PS (2009). "Fiftieth anniversary of trisomy 21: returning to a discovery" (PDF). Human Genetics. 126 (2): 317–324. doi:10.1007/s00439-009-0690-1. S2CID 30299551. Archived (PDF) from the original on 2017-02-02.

imdb.com

Life Goes On (TV Series 1989–1993) - IMDb, retrieved 2023-04-01
Champions (2023) - IMDb, retrieved 2023-04-01
The Peanut Butter Falcon (2019) - IMDb, retrieved 2023-04-01

insidethegames.biz

Liam Morgan (January 12, 2022). "IPC urged to allow greater numbers of athletes with Down's syndrome to compete at Paralympics". Insidethegames.biz. Retrieved March 2, 2024.

intellectualdisability.info

"The Genetics of Down's Syndrome". www.intellectualdisability.info. Retrieved 2023-04-01.

ispdhome.org

Benn P, Borrell A, Cuckle H, Dugoff L, Gross S, Johnson JA, et al. (January 2012). "Prenatal Detection of Down Syndrome using Massively Parallel Sequencing (MPS): a rapid response statement from a committee on behalf of the Board of the International Society for Prenatal Diagnosis, 24 October 2011" (PDF). Prenatal Diagnosis. 32 (1): 1–2. doi:10.1002/pd.2919. PMID 22275335. S2CID 42116198. Archived from the original (PDF) on 2012-03-19.

kcdsg.org

"Inclusion: Educating Students with Down Syndrome with Their Non-Disabled Peers" (PDF). National Down Syndrome Society. Archived (PDF) from the original on 27 November 2014. Retrieved 5 February 2014.

latimes.com

Randle N (1990-12-20). "'Our Ticket to Acceptance' : Actor With Down's Syndrome on 'Life Goes On' Has Become Role Model for Many". Los Angeles Times. Retrieved 2023-04-01.

lemonde.fr

"Trisomie: une pionnière intimidée". Le Monde (in French). Feb 3, 2014. Retrieved 25 March 2014.

lionsgate.com

"The Peanut Butter Falcon". Lionsgate. Retrieved 1 April 2023.

loc.gov

lccn.loc.gov

Hirata S, Hirai H, Nogami E, Morimura N, Udono T (April 2017). "Chimpanzee Down syndrome: a case study of trisomy 22 in a captive chimpanzee". Primates; Journal of Primatology. 58 (2). Springer: 267–273. doi:10.1007/s10329-017-0597-8. eISSN 1610-7365. hdl:2433/228259. LCCN sf80001417. OCLC 51531954. PMID 28220267. S2CID 5536021.

lsuhsc.edu

medschool.lsuhsc.edu

"LSUHSC School of Medicine". www.medschool.lsuhsc.edu. Retrieved 2023-04-01.

manchester.ac.uk

pure.manchester.ac.uk

Bennett R (June 2009). "The fallacy of the Principle of Procreative Beneficence". Bioethics. 23 (5): 265–273. doi:10.1111/j.1467-8519.2008.00655.x. PMID 18477055. S2CID 7373407.

mashable.com

Ariel Bogle (August 29, 2016). "Athletes with Down syndrome fight for inclusion at the Paralympics". Mashable.com. Retrieved March 2, 2024.

mayoclinic.org

"Down syndrome – Symptoms and causes". Mayo Clinic. Retrieved 17 March 2019.
"Keratoconus - Symptoms and causes". Mayo Clinic. Retrieved 2024-05-08.
"Down syndrome - Symptoms and causes". Mayo Clinic. Retrieved 2022-03-24.

mediamikes.com

Lawton A (2011-11-21). "Interview with Jamie Brewer". MediaMikes. Retrieved 2023-04-01.

medscape.com

emedicine.medscape.com

"Genetics of Down syndrome". Archived from the original on 2011-05-27. Retrieved 2011-05-29.

mencap.org.uk

"Timeline". MENCAP. Archived from the original on 17 June 2011. Retrieved 2 February 2014.

mirror.co.uk

Liam Llewellyn (November 21, 2022). "Paralympics faces calls for Down's syndrome category to ensure level playing field". Mirror. Retrieved February 10, 2024.
Liam Llewellyn (November 21, 2022). "Paralympics faces calls for Down's syndrome category to ensure level playing field". Mirror. Retrieved March 2, 2024.

nads.org

"Facts About Down Syndrome". National Association for Down Syndrome. Archived from the original on 3 April 2012. Retrieved 20 March 2012.
"Facts About Down Syndrome". National Association for Down Syndrome. Retrieved 2023-04-01.

nature.com

Mole B (2013). "Researchers turn off Down's syndrome genes". Nature News. doi:10.1038/nature.2013.13406. S2CID 87422171. Retrieved 25 December 2018.

ndsccenter.org

Kumin L. Resource Guide to Oral Motor Skill Difficulties in Children with Down Syndrome (PDF). Loyola College of Maryland.

ndss.org

"About Down Syndrome | National Down Syndrome Society (NDSS)". ndss.org. Retrieved 2023-03-28.
"What is Down Syndrome? | National Down Syndrome Society". NDSS. Retrieved 2022-03-24.
"Early Intervention – National Down Syndrome Society". www.ndss.org. Archived from the original on 2016-11-19. Retrieved 2016-11-18.
"Where Should I Go From Here?". National Down Syndrome Society. Archived from the original on 22 December 2015. Retrieved 19 December 2015.
"About Down Syndrome". National Down Syndrome Society. Retrieved 28 March 2023.

neonatology.org

Down JL (1866). "Observations on an ethnic classification of idiots". Clinical Lecture Reports, London Hospital. 3: 259–62. Archived from the original on 2006-06-15. Retrieved 2006-07-14.

nice.org.uk

publications.nice.org.uk

National Institute for Health and Clinical Excellence (2008). "CG62: Antenatal care". London: National Institute for Health and Clinical Excellence. Archived from the original on 26 January 2013. Retrieved 16 February 2013.

nih.gov

pubmed.ncbi.nlm.nih.gov

Weijerman ME, de Winter JP (December 2010). "Clinical practice. The care of children with Down syndrome". European Journal of Pediatrics. 169 (12): 1445–1452. doi:10.1007/s00431-010-1253-0. PMC 2962780. PMID 20632187.
Patterson D (July 2009). "Molecular genetic analysis of Down syndrome". Human Genetics. 126 (1): 195–214. doi:10.1007/s00439-009-0696-8. ISSN 0340-6717. PMID 19526251. S2CID 10403507.
Morris JK, Mutton DE, Alberman E (2002). "Revised estimates of the maternal age specific live birth prevalence of Down's syndrome". Journal of Medical Screening. 9 (1): 2–6. doi:10.1136/jms.9.1.2. PMID 11943789.
Roizen NJ, Patterson D (April 2003). "Down's syndrome". Lancet (Review). 361 (9365): 1281–1289. doi:10.1016/S0140-6736(03)12987-X. PMID 12699967. S2CID 33257578.
Malt EA, Dahl RC, Haugsand TM, Ulvestad IH, Emilsen NM, Hansen B, et al. (February 2013). "Health and disease in adults with Down syndrome". Tidsskrift for den Norske Laegeforening. 133 (3): 290–294. doi:10.4045/tidsskr.12.0390. PMID 23381164.
GBD 2015 Disease and Injury Incidence and Prevalence Collaborators (October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282.
Seror V, L'Haridon O, Bussières L, Malan V, Fries N, Vekemans M, et al. (March 2019). "Women's Attitudes Toward Invasive and Noninvasive Testing When Facing a High Risk of Fetal Down Syndrome". JAMA Network Open. 2 (3): e191062. doi:10.1001/jamanetworkopen.2019.1062. PMC 6450316. PMID 30924894.
Natoli JL, Ackerman DL, McDermott S, Edwards JG (February 2012). "Prenatal diagnosis of Down syndrome: a systematic review of termination rates (1995-2011)". Prenatal Diagnosis. 32 (2): 142–153. doi:10.1002/pd.2910. PMID 22418958.
Mansfield C, Hopfer S, Marteau TM (September 1999). "Termination rates after prenatal diagnosis of Down syndrome, spina bifida, anencephaly, and Turner and Klinefelter syndromes: a systematic literature review. European Concerted Action: DADA (Decision-making After the Diagnosis of a fetal Abnormality)". Prenatal Diagnosis. 19 (9). Wiley: 808–812. doi:10.1002/(sici)1097-0223(199909)19:9<808::aid-pd637>3.0.co;2-b. PMID 10521836. S2CID 29637272.
Martínez-Espinosa RM, Molina Vila MD, Reig García-Galbis M (June 2020). "Evidences from Clinical Trials in Down Syndrome: Diet, Exercise and Body Composition". International Journal of Environmental Research and Public Health. 17 (12): 4294. doi:10.3390/ijerph17124294. PMC 7344556. PMID 32560141.
GBD 2015 Mortality and Causes of Death Collaborators (October 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/s0140-6736(16)31012-1. PMC 5388903. PMID 27733281.
GBD 2013 Mortality and Causes of Death Collaborators (January 2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013". Lancet. 385 (9963): 117–171. doi:10.1016/S0140-6736(14)61682-2. PMC 4340604. PMID 25530442.
Hickey F, Hickey E, Summar KL (2012). "Medical update for children with Down syndrome for the pediatrician and family practitioner". Advances in Pediatrics. 59 (1). Elsevier BV: 137–157. doi:10.1016/j.yapd.2012.04.006. PMID 22789577.
Hippolyte L, Iglesias K, Van der Linden M, Barisnikov K (August 2010). "Social reasoning skills in adults with Down syndrome: the role of language, executive functions and socio-emotional behaviour". Journal of Intellectual Disability Research. 54 (8): 714–726. doi:10.1111/j.1365-2788.2010.01299.x. PMID 20590998.
Perkins JA (December 2009). "Overview of macroglossia and its treatment". Current Opinion in Otolaryngology & Head and Neck Surgery. 17 (6): 460–465. doi:10.1097/moo.0b013e3283317f89. PMID 19713845. S2CID 45941755.
Bull MJ, Trotter T, Santoro SL, Christensen C, Grout RW, Burke LW, et al. (Council on Genetics) (May 2022). "Health Supervision for Children and Adolescents With Down Syndrome". Pediatrics. 149 (5). doi:10.1542/peds.2022-057010. PMID 35490285. S2CID 248252638.
Bull MJ (June 2020). "Down Syndrome". The New England Journal of Medicine. 382 (24): 2344–2352. doi:10.1056/NEJMra1706537. PMID 32521135. S2CID 219586275.
Pierce M, Ramsey K, Pinter J (2 April 2019). "Trends in Obesity and Overweight in Oregon Children With Down Syndrome". Global Pediatric Health. 6: 2333794X19835640. doi:10.1177/2333794X19835640. PMC 6446252. PMID 31044152.
Winders P, Wolter-Warmerdam K, Hickey F (April 2019). "A schedule of gross motor development for children with Down syndrome". Journal of Intellectual Disability Research. 63 (4): 346–356. doi:10.1111/jir.12580. PMID 30575169. S2CID 58592265.
Reilly C (October 2012). "Behavioural phenotypes and special educational needs: is aetiology important in the classroom?". Journal of Intellectual Disability Research. 56 (10): 929–946. doi:10.1111/j.1365-2788.2012.01542.x. PMID 22471356.
Patterson T, Rapsey CM, Glue P (April 2013). "Systematic review of cognitive development across childhood in Down syndrome: implications for treatment interventions". Journal of Intellectual Disability Research. 57 (4): 306–318. doi:10.1111/j.1365-2788.2012.01536.x. PMID 23506141.
Windsperger K, Hoehl S (2021). "Development of Down Syndrome Research Over the Last Decades-What Healthcare and Education Professionals Need to Know". Frontiers in Psychiatry. 12: 749046. doi:10.3389/fpsyt.2021.749046. PMC 8712441. PMID 34970162.
Kent RD, Vorperian HK (February 2013). "Speech impairment in Down syndrome: a review". Journal of Speech, Language, and Hearing Research. 56 (1): 178–210. doi:10.1044/1092-4388(2012/12-0148). PMC 3584188. PMID 23275397.
Santoro JD, Filipink RA, Baumer NT, Bulova PD, Handen BL (2023-03-01). "Down syndrome regression disorder: updates and therapeutic advances". Current Opinion in Psychiatry. 36 (2): 96–103. doi:10.1097/YCO.0000000000000845. ISSN 1473-6578. PMID 36705008.
Weijerman ME, de Winter JP (December 2010). "Clinical practice. The care of children with Down syndrome". European Journal of Pediatrics. 169 (12): 1445–1452. doi:10.1007/s00431-010-1253-0. PMC 2962780. PMID 20632187.
Bull MJ, Trotter T, Santoro SL, Christensen C, Grout RW, THE COUNCIL ON GENETICS (2022-05-01). "Health Supervision for Children and Adolescents With Down Syndrome". Pediatrics. 149 (5). doi:10.1542/peds.2022-057010. ISSN 0031-4005. PMID 35490285.
Rodman R, Pine HS (June 2012). "The otolaryngologist's approach to the patient with Down syndrome". Otolaryngologic Clinics of North America. 45 (3): 599–629, vii–viii. doi:10.1016/j.otc.2012.03.010. PMID 22588039.
Bush D, Galambos C, Dunbar Ivy D (March 2021). "Pulmonary hypertension in children with Down syndrome". Pediatric Pulmonology. 56 (3): 621–629. doi:10.1002/ppul.24687. PMID 32049444. S2CID 211087826.
Nixon DW (March 2018). "Down Syndrome, Obesity, Alzheimer's Disease, and Cancer: A Brief Review and Hypothesis". Brain Sciences. 8 (4): 53. doi:10.3390/brainsci8040053. PMC 5924389. PMID 29587359.
Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A, et al. (July 2009). "The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes". Blood. 114 (5): 937–951. doi:10.1182/blood-2009-03-209262. PMID 19357394.
Seewald L, Taub JW, Maloney KW, McCabe ER (September 2012). "Acute leukemias in children with Down syndrome". Molecular Genetics and Metabolism. 107 (1–2): 25–30. doi:10.1016/j.ymgme.2012.07.011. PMID 22867885.
Lee P, Bhansali R, Izraeli S, Hijiya N, Crispino JD (September 2016). "The biology, pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with Down syndrome". Leukemia. 30 (9): 1816–1823. doi:10.1038/leu.2016.164. PMC 5434972. PMID 27285583.
Li J, Kalev-Zylinska ML (2022). "Advances in molecular characterization of myeloid proliferations associated with Down syndrome". Frontiers in Genetics. 13: 891214. doi:10.3389/fgene.2022.891214. PMC 9399805. PMID 36035173.
Gupte A, Al-Antary ET, Edwards H, Ravindranath Y, Ge Y, Taub JW (July 2022). "The paradox of Myeloid Leukemia associated with Down syndrome". Biochemical Pharmacology. 201: 115046. doi:10.1016/j.bcp.2022.115046. PMID 35483417. S2CID 248431139.
Tamblyn JA, Norton A, Spurgeon L, Donovan V, Bedford Russell A, Bonnici J, et al. (January 2016). "Prenatal therapy in transient abnormal myelopoiesis: a systematic review". Archives of Disease in Childhood. Fetal and Neonatal Edition. 101 (1): F67–F71. doi:10.1136/archdischild-2014-308004. PMID 25956670. S2CID 5958598.
Bhatnagar N, Nizery L, Tunstall O, Vyas P, Roberts I (October 2016). "Transient Abnormal Myelopoiesis and AML in Down Syndrome: an Update". Current Hematologic Malignancy Reports. 11 (5): 333–341. doi:10.1007/s11899-016-0338-x. PMC 5031718. PMID 27510823.
Gamis AS, Smith FO (November 2012). "Transient myeloproliferative disorder in children with Down syndrome: clarity to this enigmatic disorder". British Journal of Haematology. 159 (3): 277–287. doi:10.1111/bjh.12041. PMID 22966823. S2CID 37593917.
Graber E, Chacko E, Regelmann MO, Costin G, Rapaport R (December 2012). "Down syndrome and thyroid function". Endocrinology and Metabolism Clinics of North America. 41 (4): 735–745. doi:10.1016/j.ecl.2012.08.008. PMID 23099267.
Moore SW (August 2008). "Down syndrome and the enteric nervous system". Pediatric Surgery International. 24 (8): 873–883. doi:10.1007/s00383-008-2188-7. PMID 18633623. S2CID 11890549.
Bell J, Civil CR, Townsend GC, Brown RH (December 1989). "The prevalence of taurodontism in Down's syndrome". Journal of Mental Deficiency Research. 33 (6): 467–476. doi:10.1111/j.1365-2788.1989.tb01502.x. PMID 2533267.
Rajić Z, Mestrović SR (December 1998). "Taurodontism in Down's syndrome". Collegium Antropologicum. 22 (Suppl): 63–67. PMID 9951142.
Pradhan M, Dalal A, Khan F, Agrawal S (December 2006). "Fertility in men with Down syndrome: a case report". Fertility and Sterility. 86 (6): 1765.e1–1765.e3. doi:10.1016/j.fertnstert.2006.03.071. PMID 17094988. S2CID 32384231.
Ramasamy R, Chiba K, Butler P, Lamb DJ (June 2015). "Male biological clock: a critical analysis of advanced paternal age". Fertility and Sterility. 103 (6): 1402–1406. doi:10.1016/j.fertnstert.2015.03.011. PMC 4955707. PMID 25881878.
Lana-Elola E, Watson-Scales SD, Fisher EM, Tybulewicz VL (September 2011). "Down syndrome: searching for the genetic culprits". Disease Models & Mechanisms. 4 (5): 586–595. doi:10.1242/dmm.008078. PMC 3180222. PMID 21878459.
Patterson D, Cabelof DC (April 2012). "Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging". Mechanisms of Ageing and Development. 133 (4): 133–137. doi:10.1016/j.mad.2011.10.001. PMID 22019846. S2CID 3663890.
Weksler ME, Szabo P, Relkin NR, Reidenberg MM, Weksler BB, Coppus AM (April 2013). "Alzheimer's disease and Down's syndrome: treating two paths to dementia". Autoimmunity Reviews. 12 (6): 670–673. doi:10.1016/j.autrev.2012.10.013. PMID 23201920.
Horvath S, Garagnani P, Bacalini MG, Pirazzini C, Salvioli S, Gentilini D, et al. (June 2015). "Accelerated epigenetic aging in Down syndrome". Aging Cell. 14 (3): 491–495. doi:10.1111/acel.12325. PMC 4406678. PMID 25678027.
ACOG Committee on Practice Bulletins (January 2007). "ACOG Practice Bulletin No. 77: screening for fetal chromosomal abnormalities". Obstetrics and Gynecology. 109 (1): 217–227. doi:10.1097/00006250-200701000-00054. PMID 17197615.
Agathokleous M, Chaveeva P, Poon LC, Kosinski P, Nicolaides KH (March 2013). "Meta-analysis of second-trimester markers for trisomy 21". Ultrasound in Obstetrics & Gynecology. 41 (3): 247–261. doi:10.1002/uog.12364. PMID 23208748.
Malone FD, D'Alton ME (November 2003). "First-trimester sonographic screening for Down syndrome". Obstetrics and Gynecology. 102 (5 Pt 1): 1066–1079. doi:10.1016/j.obstetgynecol.2003.08.004. PMID 14672489. S2CID 24592539.
Canick J (June 2012). "Prenatal screening for trisomy 21: recent advances and guidelines". Clinical Chemistry and Laboratory Medicine. 50 (6): 1003–1008. doi:10.1515/cclm.2011.671. PMID 21790505. S2CID 37417471.
Alldred SK, Deeks JJ, Guo B, Neilson JP, Alfirevic Z (June 2012). "Second trimester serum tests for Down's Syndrome screening" (PDF). The Cochrane Database of Systematic Reviews. 2012 (6): CD009925. doi:10.1002/14651858.CD009925. PMC 7086392. PMID 22696388. Archived from the original (PDF) on December 9, 2019. Retrieved January 7, 2019.
Mersy E, Smits LJ, van Winden LA, de Die-Smulders CE, Paulussen AD, Macville MV, et al. (Jul–Aug 2013). "Noninvasive detection of fetal trisomy 21: systematic review and report of quality and outcomes of diagnostic accuracy studies performed between 1997 and 2012". Human Reproduction Update. 19 (4): 318–329. doi:10.1093/humupd/dmt001. PMID 23396607.
Verweij EJ, van den Oever JM, de Boer MA, Boon EM, Oepkes D (2012). "Diagnostic accuracy of noninvasive detection of fetal trisomy 21 in maternal blood: a systematic review". Fetal Diagnosis and Therapy. 31 (2): 81–86. doi:10.1159/000333060. PMID 22094923.
Benn P, Borrell A, Cuckle H, Dugoff L, Gross S, Johnson JA, et al. (January 2012). "Prenatal Detection of Down Syndrome using Massively Parallel Sequencing (MPS): a rapid response statement from a committee on behalf of the Board of the International Society for Prenatal Diagnosis, 24 October 2011" (PDF). Prenatal Diagnosis. 32 (1): 1–2. doi:10.1002/pd.2919. PMID 22275335. S2CID 42116198. Archived from the original (PDF) on 2012-03-19.
Bianchi DW, Parker RL, Wentworth J, Madankumar R, Saffer C, Das AF, et al. (February 2014). "DNA sequencing versus standard prenatal aneuploidy screening". The New England Journal of Medicine. 370 (9): 799–808. doi:10.1056/nejmoa1311037. PMID 24571752.
Tabor A, Alfirevic Z (2010). "Update on procedure-related risks for prenatal diagnosis techniques". Fetal Diagnosis and Therapy. 27 (1): 1–7. doi:10.1159/000271995. OCLC 23338607. PMID 20051662.
Choi H, Van Riper M, Thoyre S (Mar–Apr 2012). "Decision making following a prenatal diagnosis of Down syndrome: an integrative review". Journal of Midwifery & Women's Health. 57 (2): 156–164. doi:10.1111/j.1542-2011.2011.00109.x. PMID 22432488.
Bull MJ (August 2011). "Health supervision for children with Down syndrome". Pediatrics. 128 (2): 393–406. doi:10.1542/peds.2011-1605. PMID 21788214.
Roberts JE, Price J, Malkin C (2007). "Language and communication development in Down syndrome". Mental Retardation and Developmental Disabilities Research Reviews. 13 (1): 26–35. doi:10.1002/mrdd.20136. PMID 17326116.
Mohan M, Bennett C, Carpenter PK (January 2009). "Memantine for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007657. doi:10.1002/14651858.CD007657. PMC 7197456. PMID 19160343.
Mohan M, Carpenter PK, Bennett C (January 2009). "Donepezil for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007178. doi:10.1002/14651858.CD007178.pub2. PMC 7208846. PMID 19160328.
Mohan M, Bennett C, Carpenter PK (January 2009). "Rivastigmine for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007658. doi:10.1002/14651858.CD007658. PMC 7197503. PMID 19160344.
Mohan M, Bennett C, Carpenter PK (January 2009). "Galantamine for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007656. doi:10.1002/14651858.CD007656. PMC 7197502. PMID 19160342.
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. (December 2012). "Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010". Lancet. 380 (9859): 2095–2128. doi:10.1016/S0140-6736(12)61728-0. hdl:10536/DRO/DU:30050819. PMC 10790329. PMID 23245604. S2CID 1541253.
Parker SE, Mai CT, Canfield MA, Rickard R, Wang Y, Meyer RE, et al. (December 2010). "Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004-2006". Birth Defects Research. Part A, Clinical and Molecular Teratology. 88 (12): 1008–1016. doi:10.1002/bdra.20735. PMID 20878909.
Levitas AS, Reid CS (February 2003). "An angel with Down syndrome in a sixteenth century Flemish Nativity painting". American Journal of Medical Genetics. Part A. 116A (4): 399–405. doi:10.1002/ajmg.a.10043. PMID 12522800. S2CID 8821338. We have identified a 16th-century Flemish Nativity painting in which one angelic figure appears distinctly different from other individuals in the painting with an appearance of Down syndrome.
Neri G, Opitz JM (December 2009). "Down syndrome: comments and reflections on the 50th anniversary of Lejeune's discovery". American Journal of Medical Genetics. Part A. 149A (12): 2647–2654. doi:10.1002/ajmg.a.33138. PMID 19921741. S2CID 12945876.
Rodríguez-Hernández ML, Montoya E (July 2011). "Fifty years of evolution of the term Down's syndrome". Lancet. 378 (9789): 402. doi:10.1016/s0140-6736(11)61212-9. PMID 21803206. S2CID 8541289.
Howard-Jones N (January 1979). "On the diagnostic term "Down's disease"". Medical History. 23 (1): 102–4. doi:10.1017/s0025727300051048. PMC 1082401. PMID 153994.
Bernal JE, Briceno I (September 2006). "Genetic and other diseases in the pottery of Tumaco-La Tolita culture in Colombia-Ecuador". Clinical Genetics. 70 (3): 188–191. doi:10.1111/j.1399-0004.2006.00670.x. PMID 16922718. S2CID 27716271.
Pain E (February 2014). "History of science. After more than 50 years, a dispute over Down syndrome discovery". Science. 343 (6172): 720–721. Bibcode:2014Sci...343..720P. doi:10.1126/science.343.6172.720. PMID 24531949.
"Classification and nomenclature of morphological defects". Lancet. 1 (7905): 513. March 1975. doi:10.1016/S0140-6736(75)92847-0. PMID 46972. S2CID 37636187.
Chervenak FA, McCullough LB (April 2010). "Ethical considerations in first-trimester Down syndrome risk assessment". Current Opinion in Obstetrics & Gynecology. 22 (2): 135–138. doi:10.1097/gco.0b013e3283374a9f. PMID 20125014. S2CID 2017130.
Ravitsky V, Roy MC, Haidar H, Henneman L, Marshall J, Newson AJ, Ngan OM, Nov-Klaiman T (2021-08-31). "The Emergence and Global Spread of Noninvasive Prenatal Testing". Annual Review of Genomics and Human Genetics. 22 (1): 309–338. doi:10.1146/annurev-genom-083118-015053. ISSN 1527-8204. PMID 33848430.
Sharma G, McCullough LB, Chervenak FA (February 2007). "Ethical considerations of early (first vs. second trimester) risk assessment disclosure for trisomy 21 and patient choice in screening versus diagnostic testing". American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 145C (1): 99–104. doi:10.1002/ajmg.c.30118. PMID 17299736.
Savulescu J, Kahane G (June 2009). "The moral obligation to create children with the best chance of the best life". Bioethics. 23 (5): 274–290. doi:10.1111/j.1467-8519.2008.00687.x. PMID 19076124. S2CID 13897639.
Bennett R (June 2009). "The fallacy of the Principle of Procreative Beneficence". Bioethics. 23 (5): 265–273. doi:10.1111/j.1467-8519.2008.00655.x. PMID 18477055. S2CID 7373407.
Parens E, Asch A (2003). "Disability rights critique of prenatal genetic testing: reflections and recommendations". Mental Retardation and Developmental Disabilities Research Reviews. 9 (1): 40–47. doi:10.1002/mrdd.10056. PMID 12587137.
Green RM (Spring 1997). "Parental autonomy and the obligation not to harm one's child genetically". The Journal of Law, Medicine & Ethics. 25 (1): 5–15, 2. doi:10.1111/j.1748-720x.1997.tb01389.x. PMID 11066476. S2CID 38939256.
Briggs JA, Mason EA, Ovchinnikov DA, Wells CA, Wolvetang EJ (March 2013). "Concise review: new paradigms for Down syndrome research using induced pluripotent stem cells: tackling complex human genetic disease". Stem Cells Translational Medicine. 2 (3): 175–184. doi:10.5966/sctm.2012-0117. PMC 3659762. PMID 23413375.
Goodman MJ, Brixner DI (April 2013). "New therapies for treating Down syndrome require quality of life measurement". American Journal of Medical Genetics. Part A. 161A (4): 639–641. doi:10.1002/ajmg.a.35705. PMID 23495233. S2CID 43840950.
Fillat C, Altafaj X (2012). "Gene therapy for Down syndrome". Down Syndrome: From Understanding the Neurobiology to Therapy. Progress in Brain Research. Vol. 197. pp. 237–47. doi:10.1016/B978-0-444-54299-1.00012-1. ISBN 9780444542991. PMID 22541296.
Costa AC, Scott-McKean JJ (September 2013). "Prospects for improving brain function in individuals with Down syndrome". CNS Drugs. 27 (9): 679–702. doi:10.1007/s40263-013-0089-3. PMID 23821040. S2CID 24030020.
Costa AC (2011). "On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of Down syndrome". Developmental Neuroscience. 33 (5): 414–427. doi:10.1159/000330861. PMC 3254040. PMID 21893967.
Hirata S, Hirai H, Nogami E, Morimura N, Udono T (April 2017). "Chimpanzee Down syndrome: a case study of trisomy 22 in a captive chimpanzee". Primates; Journal of Primatology. 58 (2). Springer: 267–273. doi:10.1007/s10329-017-0597-8. eISSN 1610-7365. hdl:2433/228259. LCCN sf80001417. OCLC 51531954. PMID 28220267. S2CID 5536021.
Conde-Valverde M, Quirós-Sánchez A, Diez-Valero J, Mata-Castro N, García-Fernández A, Quam R, Carretero JM, García-González R, Rodríguez L, Sánchez-Andrés Á, Arsuaga JL, Martínez I, Villaverde V (2024). "The child who lived: Down syndrome among Neanderthals?". Science Advances. 10 (26): eadn9310. Bibcode:2024SciA...10N9310C. doi:10.1126/sciadv.adn9310. PMC 11204207. PMID 38924400.

ncbi.nlm.nih.gov

Weijerman ME, de Winter JP (December 2010). "Clinical practice. The care of children with Down syndrome". European Journal of Pediatrics. 169 (12): 1445–1452. doi:10.1007/s00431-010-1253-0. PMC 2962780. PMID 20632187.
GBD 2015 Disease and Injury Incidence and Prevalence Collaborators (October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282.
Seror V, L'Haridon O, Bussières L, Malan V, Fries N, Vekemans M, et al. (March 2019). "Women's Attitudes Toward Invasive and Noninvasive Testing When Facing a High Risk of Fetal Down Syndrome". JAMA Network Open. 2 (3): e191062. doi:10.1001/jamanetworkopen.2019.1062. PMC 6450316. PMID 30924894.
Martínez-Espinosa RM, Molina Vila MD, Reig García-Galbis M (June 2020). "Evidences from Clinical Trials in Down Syndrome: Diet, Exercise and Body Composition". International Journal of Environmental Research and Public Health. 17 (12): 4294. doi:10.3390/ijerph17124294. PMC 7344556. PMID 32560141.
GBD 2015 Mortality and Causes of Death Collaborators (October 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/s0140-6736(16)31012-1. PMC 5388903. PMID 27733281.
GBD 2013 Mortality and Causes of Death Collaborators (January 2015). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013". Lancet. 385 (9963): 117–171. doi:10.1016/S0140-6736(14)61682-2. PMC 4340604. PMID 25530442.
Pierce M, Ramsey K, Pinter J (2 April 2019). "Trends in Obesity and Overweight in Oregon Children With Down Syndrome". Global Pediatric Health. 6: 2333794X19835640. doi:10.1177/2333794X19835640. PMC 6446252. PMID 31044152.
Windsperger K, Hoehl S (2021). "Development of Down Syndrome Research Over the Last Decades-What Healthcare and Education Professionals Need to Know". Frontiers in Psychiatry. 12: 749046. doi:10.3389/fpsyt.2021.749046. PMC 8712441. PMID 34970162.
Kent RD, Vorperian HK (February 2013). "Speech impairment in Down syndrome: a review". Journal of Speech, Language, and Hearing Research. 56 (1): 178–210. doi:10.1044/1092-4388(2012/12-0148). PMC 3584188. PMID 23275397.
Weijerman ME, de Winter JP (December 2010). "Clinical practice. The care of children with Down syndrome". European Journal of Pediatrics. 169 (12): 1445–1452. doi:10.1007/s00431-010-1253-0. PMC 2962780. PMID 20632187.
Nixon DW (March 2018). "Down Syndrome, Obesity, Alzheimer's Disease, and Cancer: A Brief Review and Hypothesis". Brain Sciences. 8 (4): 53. doi:10.3390/brainsci8040053. PMC 5924389. PMID 29587359.
Lee P, Bhansali R, Izraeli S, Hijiya N, Crispino JD (September 2016). "The biology, pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with Down syndrome". Leukemia. 30 (9): 1816–1823. doi:10.1038/leu.2016.164. PMC 5434972. PMID 27285583.
Li J, Kalev-Zylinska ML (2022). "Advances in molecular characterization of myeloid proliferations associated with Down syndrome". Frontiers in Genetics. 13: 891214. doi:10.3389/fgene.2022.891214. PMC 9399805. PMID 36035173.
Bhatnagar N, Nizery L, Tunstall O, Vyas P, Roberts I (October 2016). "Transient Abnormal Myelopoiesis and AML in Down Syndrome: an Update". Current Hematologic Malignancy Reports. 11 (5): 333–341. doi:10.1007/s11899-016-0338-x. PMC 5031718. PMID 27510823.
Ramasamy R, Chiba K, Butler P, Lamb DJ (June 2015). "Male biological clock: a critical analysis of advanced paternal age". Fertility and Sterility. 103 (6): 1402–1406. doi:10.1016/j.fertnstert.2015.03.011. PMC 4955707. PMID 25881878.
Lana-Elola E, Watson-Scales SD, Fisher EM, Tybulewicz VL (September 2011). "Down syndrome: searching for the genetic culprits". Disease Models & Mechanisms. 4 (5): 586–595. doi:10.1242/dmm.008078. PMC 3180222. PMID 21878459.
Horvath S, Garagnani P, Bacalini MG, Pirazzini C, Salvioli S, Gentilini D, et al. (June 2015). "Accelerated epigenetic aging in Down syndrome". Aging Cell. 14 (3): 491–495. doi:10.1111/acel.12325. PMC 4406678. PMID 25678027.
Alldred SK, Deeks JJ, Guo B, Neilson JP, Alfirevic Z (June 2012). "Second trimester serum tests for Down's Syndrome screening" (PDF). The Cochrane Database of Systematic Reviews. 2012 (6): CD009925. doi:10.1002/14651858.CD009925. PMC 7086392. PMID 22696388. Archived from the original (PDF) on December 9, 2019. Retrieved January 7, 2019.
Mohan M, Bennett C, Carpenter PK (January 2009). "Memantine for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007657. doi:10.1002/14651858.CD007657. PMC 7197456. PMID 19160343.
Mohan M, Carpenter PK, Bennett C (January 2009). "Donepezil for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007178. doi:10.1002/14651858.CD007178.pub2. PMC 7208846. PMID 19160328.
Mohan M, Bennett C, Carpenter PK (January 2009). "Rivastigmine for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007658. doi:10.1002/14651858.CD007658. PMC 7197503. PMID 19160344.
Mohan M, Bennett C, Carpenter PK (January 2009). "Galantamine for dementia in people with Down syndrome". The Cochrane Database of Systematic Reviews. 2009 (1): CD007656. doi:10.1002/14651858.CD007656. PMC 7197502. PMID 19160342.
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. (December 2012). "Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010". Lancet. 380 (9859): 2095–2128. doi:10.1016/S0140-6736(12)61728-0. hdl:10536/DRO/DU:30050819. PMC 10790329. PMID 23245604. S2CID 1541253.
Howard-Jones N (January 1979). "On the diagnostic term "Down's disease"". Medical History. 23 (1): 102–4. doi:10.1017/s0025727300051048. PMC 1082401. PMID 153994.
Briggs JA, Mason EA, Ovchinnikov DA, Wells CA, Wolvetang EJ (March 2013). "Concise review: new paradigms for Down syndrome research using induced pluripotent stem cells: tackling complex human genetic disease". Stem Cells Translational Medicine. 2 (3): 175–184. doi:10.5966/sctm.2012-0117. PMC 3659762. PMID 23413375.
Costa AC (2011). "On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of Down syndrome". Developmental Neuroscience. 33 (5): 414–427. doi:10.1159/000330861. PMC 3254040. PMID 21893967.
Conde-Valverde M, Quirós-Sánchez A, Diez-Valero J, Mata-Castro N, García-Fernández A, Quam R, Carretero JM, García-González R, Rodríguez L, Sánchez-Andrés Á, Arsuaga JL, Martínez I, Villaverde V (2024). "The child who lived: Down syndrome among Neanderthals?". Science Advances. 10 (26): eadn9310. Bibcode:2024SciA...10N9310C. doi:10.1126/sciadv.adn9310. PMC 11204207. PMID 38924400.

nichd.nih.gov

"What causes Down syndrome?". National Institute of Child Health and Human Development. U.S. National Institutes of Health. 2014-01-17. Archived from the original on 5 January 2016. Retrieved 6 January 2016.
"How do health care providers diagnose Down syndrome?". Eunice Kennedy Shriver National Institute of Child Health and Human Development. 2014-01-17. Archived from the original on 7 March 2016. Retrieved 4 March 2016.
"What are common symptoms of Down syndrome?". NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development. 31 January 2017. Retrieved 28 March 2023.
"Down Syndrome: Other FAQs". 2014-01-17. Archived from the original on 6 January 2016. Retrieved 6 January 2016.
"What are common treatments for Down syndrome?". NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development. 31 January 2017. Retrieved 28 March 2023.

nottingham.ac.uk

eprints.nottingham.ac.uk

Alldred SK, Deeks JJ, Guo B, Neilson JP, Alfirevic Z (June 2012). "Second trimester serum tests for Down's Syndrome screening" (PDF). The Cochrane Database of Systematic Reviews. 2012 (6): CD009925. doi:10.1002/14651858.CD009925. PMC 7086392. PMID 22696388. Archived from the original (PDF) on December 9, 2019. Retrieved January 7, 2019.

nytimes.com

parenting.blogs.nytimes.com

Belkin L (2010-01-11). "Should Down Syndrome Be Cured?". Archived from the original on 2015-04-25. Retrieved 2015-09-26.

oprah.com

"Life Goes On Actor Chris Burke on Being the First Primetime Television Star with Down Syndrome". Oprah.com. Archived from the original on 14 August 2015. Retrieved 2023-04-01.

ox.ac.uk

ora.ox.ac.uk

Tamblyn JA, Norton A, Spurgeon L, Donovan V, Bedford Russell A, Bonnici J, et al. (January 2016). "Prenatal therapy in transient abnormal myelopoiesis: a systematic review". Archives of Disease in Childhood. Fetal and Neonatal Edition. 101 (1): F67–F71. doi:10.1136/archdischild-2014-308004. PMID 25956670. S2CID 5958598.

oxhp.com

"Noninvasive prenatal diagnosis of fetal aneuploidy using cell-free fetal nucleic acids in maternal blood" (PDF). United Healthcare Oxford. Archived (PDF) from the original on 7 March 2014. Retrieved 25 March 2014.

people.com

Mier T (17 February 2020). "NYFW: Model with Down Syndrome Says 'There Are No Limits'". Peoplemag. Retrieved 2023-04-01.

phys.org

"First case of Down syndrome in Neanderthals documented in new study".

portlandpress.com

Sansom C (October 2015). "The evolution of human chromosome 2" (PDF). The Biochemist. 37 (5): 40–41. doi:10.1042/BIO03705040.

portugalresident.com

"Special21 celebrates World Down Syndrome Day in Albufeira". Portugal Resident. March 25, 2022. Retrieved March 13, 2024.
"Algarve swimmer with Down syndrome breaks world record". Portugal Resident. February 27, 2019. Retrieved March 13, 2024.
"Special21 celebrates World Down Syndrome Day in Albufeira". Portugal Resident. March 25, 2022. Retrieved March 2, 2024.

prnewswire.com

Obagi. "Obagi Announces Partnership with Down Syndrome Advocate, Grace Strobel, as new SKINCLUSION Ambassador and Face of New Obagi Clinical Cleanser". www.prnewswire.com (Press release). Retrieved 2023-04-01.
Obagi. "Obagi Clinical® Continues Collaboration with Down Syndrome Advocate Grace Strobel". www.prnewswire.com (Press release). Retrieved 2023-04-01.

rehacare.com

"Down's Syndrome: Employment Barriers". Rehab Care International. Archived from the original on 22 February 2014. Retrieved 7 February 2014.

rte.ie

"Genetics study shines light on early periods of Ireland's human history". www.rte.ie. Raidió Teilifís Éireann. 17 June 2020. Retrieved 17 June 2020.

semanticscholar.org

api.semanticscholar.org

Patterson D (July 2009). "Molecular genetic analysis of Down syndrome". Human Genetics. 126 (1): 195–214. doi:10.1007/s00439-009-0696-8. ISSN 0340-6717. PMID 19526251. S2CID 10403507.
Roizen NJ, Patterson D (April 2003). "Down's syndrome". Lancet (Review). 361 (9365): 1281–1289. doi:10.1016/S0140-6736(03)12987-X. PMID 12699967. S2CID 33257578.
Mansfield C, Hopfer S, Marteau TM (September 1999). "Termination rates after prenatal diagnosis of Down syndrome, spina bifida, anencephaly, and Turner and Klinefelter syndromes: a systematic literature review. European Concerted Action: DADA (Decision-making After the Diagnosis of a fetal Abnormality)". Prenatal Diagnosis. 19 (9). Wiley: 808–812. doi:10.1002/(sici)1097-0223(199909)19:9<808::aid-pd637>3.0.co;2-b. PMID 10521836. S2CID 29637272.
Perkins JA (December 2009). "Overview of macroglossia and its treatment". Current Opinion in Otolaryngology & Head and Neck Surgery. 17 (6): 460–465. doi:10.1097/moo.0b013e3283317f89. PMID 19713845. S2CID 45941755.
Bull MJ, Trotter T, Santoro SL, Christensen C, Grout RW, Burke LW, et al. (Council on Genetics) (May 2022). "Health Supervision for Children and Adolescents With Down Syndrome". Pediatrics. 149 (5). doi:10.1542/peds.2022-057010. PMID 35490285. S2CID 248252638.
Bull MJ (June 2020). "Down Syndrome". The New England Journal of Medicine. 382 (24): 2344–2352. doi:10.1056/NEJMra1706537. PMID 32521135. S2CID 219586275.
Winders P, Wolter-Warmerdam K, Hickey F (April 2019). "A schedule of gross motor development for children with Down syndrome". Journal of Intellectual Disability Research. 63 (4): 346–356. doi:10.1111/jir.12580. PMID 30575169. S2CID 58592265.
Bush D, Galambos C, Dunbar Ivy D (March 2021). "Pulmonary hypertension in children with Down syndrome". Pediatric Pulmonology. 56 (3): 621–629. doi:10.1002/ppul.24687. PMID 32049444. S2CID 211087826.
Gupte A, Al-Antary ET, Edwards H, Ravindranath Y, Ge Y, Taub JW (July 2022). "The paradox of Myeloid Leukemia associated with Down syndrome". Biochemical Pharmacology. 201: 115046. doi:10.1016/j.bcp.2022.115046. PMID 35483417. S2CID 248431139.
Tamblyn JA, Norton A, Spurgeon L, Donovan V, Bedford Russell A, Bonnici J, et al. (January 2016). "Prenatal therapy in transient abnormal myelopoiesis: a systematic review". Archives of Disease in Childhood. Fetal and Neonatal Edition. 101 (1): F67–F71. doi:10.1136/archdischild-2014-308004. PMID 25956670. S2CID 5958598.
Gamis AS, Smith FO (November 2012). "Transient myeloproliferative disorder in children with Down syndrome: clarity to this enigmatic disorder". British Journal of Haematology. 159 (3): 277–287. doi:10.1111/bjh.12041. PMID 22966823. S2CID 37593917.
Moore SW (August 2008). "Down syndrome and the enteric nervous system". Pediatric Surgery International. 24 (8): 873–883. doi:10.1007/s00383-008-2188-7. PMID 18633623. S2CID 11890549.
Pradhan M, Dalal A, Khan F, Agrawal S (December 2006). "Fertility in men with Down syndrome: a case report". Fertility and Sterility. 86 (6): 1765.e1–1765.e3. doi:10.1016/j.fertnstert.2006.03.071. PMID 17094988. S2CID 32384231.
Patterson D, Cabelof DC (April 2012). "Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging". Mechanisms of Ageing and Development. 133 (4): 133–137. doi:10.1016/j.mad.2011.10.001. PMID 22019846. S2CID 3663890.
Malone FD, D'Alton ME (November 2003). "First-trimester sonographic screening for Down syndrome". Obstetrics and Gynecology. 102 (5 Pt 1): 1066–1079. doi:10.1016/j.obstetgynecol.2003.08.004. PMID 14672489. S2CID 24592539.
Canick J (June 2012). "Prenatal screening for trisomy 21: recent advances and guidelines". Clinical Chemistry and Laboratory Medicine. 50 (6): 1003–1008. doi:10.1515/cclm.2011.671. PMID 21790505. S2CID 37417471.
Benn P, Borrell A, Cuckle H, Dugoff L, Gross S, Johnson JA, et al. (January 2012). "Prenatal Detection of Down Syndrome using Massively Parallel Sequencing (MPS): a rapid response statement from a committee on behalf of the Board of the International Society for Prenatal Diagnosis, 24 October 2011" (PDF). Prenatal Diagnosis. 32 (1): 1–2. doi:10.1002/pd.2919. PMID 22275335. S2CID 42116198. Archived from the original (PDF) on 2012-03-19.
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. (December 2012). "Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010". Lancet. 380 (9859): 2095–2128. doi:10.1016/S0140-6736(12)61728-0. hdl:10536/DRO/DU:30050819. PMC 10790329. PMID 23245604. S2CID 1541253.
Levitas AS, Reid CS (February 2003). "An angel with Down syndrome in a sixteenth century Flemish Nativity painting". American Journal of Medical Genetics. Part A. 116A (4): 399–405. doi:10.1002/ajmg.a.10043. PMID 12522800. S2CID 8821338. We have identified a 16th-century Flemish Nativity painting in which one angelic figure appears distinctly different from other individuals in the painting with an appearance of Down syndrome.
Neri G, Opitz JM (December 2009). "Down syndrome: comments and reflections on the 50th anniversary of Lejeune's discovery". American Journal of Medical Genetics. Part A. 149A (12): 2647–2654. doi:10.1002/ajmg.a.33138. PMID 19921741. S2CID 12945876.
Rodríguez-Hernández ML, Montoya E (July 2011). "Fifty years of evolution of the term Down's syndrome". Lancet. 378 (9789): 402. doi:10.1016/s0140-6736(11)61212-9. PMID 21803206. S2CID 8541289.
Bernal JE, Briceno I (September 2006). "Genetic and other diseases in the pottery of Tumaco-La Tolita culture in Colombia-Ecuador". Clinical Genetics. 70 (3): 188–191. doi:10.1111/j.1399-0004.2006.00670.x. PMID 16922718. S2CID 27716271.
Gautier M, Harper PS (2009). "Fiftieth anniversary of trisomy 21: returning to a discovery" (PDF). Human Genetics. 126 (2): 317–324. doi:10.1007/s00439-009-0690-1. S2CID 30299551. Archived (PDF) from the original on 2017-02-02.
"Classification and nomenclature of morphological defects". Lancet. 1 (7905): 513. March 1975. doi:10.1016/S0140-6736(75)92847-0. PMID 46972. S2CID 37636187.
Chervenak FA, McCullough LB (April 2010). "Ethical considerations in first-trimester Down syndrome risk assessment". Current Opinion in Obstetrics & Gynecology. 22 (2): 135–138. doi:10.1097/gco.0b013e3283374a9f. PMID 20125014. S2CID 2017130.
Savulescu J, Kahane G (June 2009). "The moral obligation to create children with the best chance of the best life". Bioethics. 23 (5): 274–290. doi:10.1111/j.1467-8519.2008.00687.x. PMID 19076124. S2CID 13897639.
Bennett R (June 2009). "The fallacy of the Principle of Procreative Beneficence". Bioethics. 23 (5): 265–273. doi:10.1111/j.1467-8519.2008.00655.x. PMID 18477055. S2CID 7373407.
Green RM (Spring 1997). "Parental autonomy and the obligation not to harm one's child genetically". The Journal of Law, Medicine & Ethics. 25 (1): 5–15, 2. doi:10.1111/j.1748-720x.1997.tb01389.x. PMID 11066476. S2CID 38939256.
Goodman MJ, Brixner DI (April 2013). "New therapies for treating Down syndrome require quality of life measurement". American Journal of Medical Genetics. Part A. 161A (4): 639–641. doi:10.1002/ajmg.a.35705. PMID 23495233. S2CID 43840950.
Mole B (2013). "Researchers turn off Down's syndrome genes". Nature News. doi:10.1038/nature.2013.13406. S2CID 87422171. Retrieved 25 December 2018.
Costa AC, Scott-McKean JJ (September 2013). "Prospects for improving brain function in individuals with Down syndrome". CNS Drugs. 27 (9): 679–702. doi:10.1007/s40263-013-0089-3. PMID 23821040. S2CID 24030020.
Hirata S, Hirai H, Nogami E, Morimura N, Udono T (April 2017). "Chimpanzee Down syndrome: a case study of trisomy 22 in a captive chimpanzee". Primates; Journal of Primatology. 58 (2). Springer: 267–273. doi:10.1007/s10329-017-0597-8. eISSN 1610-7365. hdl:2433/228259. LCCN sf80001417. OCLC 51531954. PMID 28220267. S2CID 5536021.

skysports.com

Rebecca Williams (March 11, 2022). "Paralympic dream for British Down syndrome swimmers at first national championships". Sky Sports. Retrieved March 2, 2024.

slate.com

Graham R (2018-05-31). "How Down Syndrome Is Redefining the Abortion Debate". Slate Magazine. Retrieved 2019-01-09.

sofiajirau.com

"About me". Sofia Jirau Model. Retrieved 2023-04-01.

special21.org

"Special21 About Us". Special21.org. Retrieved March 13, 2024.

theguardian.com

Marsh S (25 April 2023). "Barbie doll with Down's syndrome launched by Mattel". The Guardian.

themighty.com

V J. "Latina Model With Down Syndrome Walks at New York Fashion Week". The Mighty. Retrieved 2023-04-01.

upi.com

Hays B. "Second case of 'Down syndrome' in chimpanzees identified in Japan". UPI. Retrieved 11 May 2019.

uptodate.com

Halliday JV, Messerlian GM, Palomaki GE. "Patient education: Should I have a screening test for Down syndrome during pregnancy? (Beyond the Basics)". UpToDate.

usatoday.com

Szabo L (May 9, 2013). "Life with Down syndrome is full of possibilities". USA Today. Archived from the original on 8 January 2014. Retrieved 7 February 2014.

usmagazine.com

Holender S (2022-02-17). "Meet Sofia Jirau, Victoria's Secret's 1st Model With Down Syndrome". Us Weekly. Retrieved 2023-04-01.

vaticannews.va

Vet C (July 24, 2019). "Religious Sisters with Down syndrome: the joy of shared contemplative life". Vatican News. Retrieved July 31, 2019.

vogue.mx

"Sofía Jirau, la modelo latina con síndrome de down que decantó en el Fashion Week de Nueva York". Vogue (in Mexican Spanish). 2020-02-13. Retrieved 2023-04-01.

web.archive.org

"What causes Down syndrome?". National Institute of Child Health and Human Development. U.S. National Institutes of Health. 2014-01-17. Archived from the original on 5 January 2016. Retrieved 6 January 2016.
"How do health care providers diagnose Down syndrome?". Eunice Kennedy Shriver National Institute of Child Health and Human Development. 2014-01-17. Archived from the original on 7 March 2016. Retrieved 4 March 2016.
"Facts About Down Syndrome". National Association for Down Syndrome. Archived from the original on 3 April 2012. Retrieved 20 March 2012.
Smith K (2011). The politics of Down syndrome. [New Alresford, Hampshire]: Zero. p. 3. ISBN 978-1-84694-613-4. Archived from the original on 2017-01-23.
"Down Syndrome: Other FAQs". 2014-01-17. Archived from the original on 6 January 2016. Retrieved 6 January 2016.
Steinbock B (2011). "The Risk of Transmitting Disease or Disability". Life before birth the moral and legal status of embryos and fetuses (2nd ed.). Oxford: Oxford University Press. p. 222. ISBN 978-0-19-971207-6. Archived from the original on 2017-01-23.
Szabo L (May 9, 2013). "Life with Down syndrome is full of possibilities". USA Today. Archived from the original on 8 January 2014. Retrieved 7 February 2014.
Faragher R, Clarke B, eds. (2013). "Introduction". Educating Learners with Down Syndrome: Research, theory, and practice with children and adolescents. Taylor & Francis. p. 5. ISBN 978-1-134-67335-3. Archived from the original on 2017-01-23.
Johnston JM, Smyth MD, McKinstry RC (2008). "Basics of Neuroimaging in Pediatric Epilepsy". In Pellock JM, Bourgeois BF, Dodson WE, Nordli Jr DR, Sankar R (eds.). Pediatric epilepsy diagnosis and therapy (3rd ed.). New York: Demos Medical Pub. p. Chapter 67. ISBN 978-1-934559-86-4. Archived from the original on 2017-01-23.
Epstein CJ (2007). The consequences of chromosome imbalance: principles, mechanisms, and models. Cambridge: Cambridge University Press. pp. 255–256. ISBN 978-0-521-03809-6. Archived from the original on 2017-01-23.
Marion RW, Samanich JN (2012). "Genetics". In Bernstein D, Shelov SP (eds.). Pediatrics for medical students (3rd ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 259. ISBN 978-0-7817-7030-9. Archived from the original on 2017-01-23.
Bertoti DB, Smith DE (2008). "Mental Retardation: Focus on Down Syndrome". In Tecklin JS (ed.). Pediatric physical therapy (4th ed.). Philadelphia: Lippincott Williams & Wilkins. p. 380. ISBN 978-0-7817-5399-9. Archived from the original on 2017-01-23.
Domino FJ, ed. (2007). The 5-minute clinical consult 2007 (2007 ed.). Philadelphia: Lippincott Williams & Wilkins. p. 392. ISBN 978-0-7817-6334-9. Archived from the original on 2017-01-23.
Wilson GN, Cooley WC (2006). Preventive management of children with congenital anomalies and syndromes (2nd ed.). Cambridge: Cambridge University Press. p. 190. ISBN 978-0-521-61734-5. Archived from the original on 2017-01-23.
Williams Textbook of Endocrinology Expert Consult (12th ed.). London: Elsevier Health Sciences. 2011. ISBN 978-1-4377-3600-7. Archived from the original on 2017-01-23.
Batshaw M, ed. (2005). Children with disabilities (5th ed.). Baltimore [u.a.]: Paul H. Brookes. p. 308. ISBN 978-1-55766-581-2. Archived from the original on 2017-01-23.
Schwartz MW, ed. (2012). The 5-minute pediatric consult (6th ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 289. ISBN 978-1-4511-1656-4. Archived from the original on 2017-01-23.
Goldstein S, ed. (2011). Handbook of neurodevelopmental and genetic disorders in children (2nd ed.). New York: Guilford Press. p. 365. ISBN 978-1-60623-990-2. Archived from the original on 2017-01-23.
Prasher VP (2009). Neuropsychological assessments of dementia in Down syndrome and intellectual disabilities. London: Springer. p. 56. ISBN 978-1-84800-249-4. Archived from the original on 2017-01-23.
Urbano R (9 September 2010). Health Issues Among Persons With Down Syndrome. Academic Press. p. 129. ISBN 978-0-12-374477-7. Archived from the original on 12 May 2015.
Thomas-Tikhonenko A, ed. (2010). Cancer genome and tumor microenvironment (Online-Ausg. ed.). New York: Springer. p. 203. ISBN 978-1-4419-0711-0. Archived from the original on 2015-07-04.
Nelson MR (2011). Pediatrics. New York: Demos Medical. p. 88. ISBN 978-1-61705-004-6. Archived from the original on 2017-01-23.
Reisner H (2013). Essentials of Rubin's Pathology. Lippincott Williams & Wilkins. pp. 129–131. ISBN 978-1-4511-8132-6. Archived from the original on 2017-01-23.
"Birth Defects, Down Syndrome". National Center on Birth Defects and Developmental Disabilities. US: Centers for Disease Control and Prevention. 2013-11-06. Archived from the original on 2017-07-28.
Mandal K (2013). Treatment & prognosis in pediatrics. Jaypee Brothers Medical P. p. 391. ISBN 978-93-5090-428-2. Archived from the original on 2017-01-23.
Fletcher-Janzen E, Reynolds CR (2007). Encyclopedia of special education: a reference for the education of children, adolescents, and adults with disabilities and other exceptional individuals (3rd ed.). New York: John Wiley & Sons. p. 458. ISBN 978-0-470-17419-7. Archived from the original on 2017-01-23.
Zhang DY, Cheng L (2008). Molecular genetic pathology. Totowa, N.J.: Humana. p. 45. ISBN 978-1-59745-405-6. Archived from the original on 2017-01-23.
David AK (2013). Family Medicine Principles and Practice (Sixth ed.). New York, NY: Springer New York. p. 142. ISBN 978-0-387-21744-4. Archived from the original on 2017-01-23.
Cummings M (2013). Human Heredity: Principles and Issues (10th ed.). Cengage Learning. p. 138. ISBN 978-1-285-52847-2. Archived from the original on 2017-01-23.
Strauss JF, Barbieri RL (2009). Yen and Jaffe's reproductive endocrinology: physiology, pathophysiology, and clinical management (6th ed.). Philadelphia, PA: Saunders/Elsevier. p. 791. ISBN 978-1-4160-4907-4. Archived from the original on 2017-01-23.
Menkes JH, Sarnat HB (2005). Child neurology (7th ed.). Philadelphia, PA: Lippincott Williams & Wilkins. p. 228. ISBN 978-0-7817-5104-9. Archived from the original on 2017-01-23.
Gardner RJ, Sutherland GR, Shaffer LG, eds. (2012). Chromosome abnormalities and genetic counseling (4th ed.). Oxford: Oxford University Press. p. 292. ISBN 978-0-19-974915-7. Archived from the original on 2017-01-23.
"Genetics of Down syndrome". Archived from the original on 2011-05-27. Retrieved 2011-05-29.
National Institute for Health and Clinical Excellence (2008). "CG62: Antenatal care". London: National Institute for Health and Clinical Excellence. Archived from the original on 26 January 2013. Retrieved 16 February 2013.
Alldred SK, Deeks JJ, Guo B, Neilson JP, Alfirevic Z (June 2012). "Second trimester serum tests for Down's Syndrome screening" (PDF). The Cochrane Database of Systematic Reviews. 2012 (6): CD009925. doi:10.1002/14651858.CD009925. PMC 7086392. PMID 22696388. Archived from the original (PDF) on December 9, 2019. Retrieved January 7, 2019.
Benn P, Borrell A, Cuckle H, Dugoff L, Gross S, Johnson JA, et al. (January 2012). "Prenatal Detection of Down Syndrome using Massively Parallel Sequencing (MPS): a rapid response statement from a committee on behalf of the Board of the International Society for Prenatal Diagnosis, 24 October 2011" (PDF). Prenatal Diagnosis. 32 (1): 1–2. doi:10.1002/pd.2919. PMID 22275335. S2CID 42116198. Archived from the original (PDF) on 2012-03-19.
"Noninvasive prenatal diagnosis of fetal aneuploidy using cell-free fetal nucleic acids in maternal blood" (PDF). United Healthcare Oxford. Archived (PDF) from the original on 7 March 2014. Retrieved 25 March 2014.
"Inclusion: Educating Students with Down Syndrome with Their Non-Disabled Peers" (PDF). National Down Syndrome Society. Archived (PDF) from the original on 27 November 2014. Retrieved 5 February 2014.
New RS, Cochran M (2007). Early childhood education an international encyclopedia. Westport, Conn.: Praeger Publishers. p. 305. ISBN 978-0-313-01448-2. Archived from the original on 2017-01-23.
"Development and learning for people with Down syndrome". Archived from the original on 2016-11-19. Retrieved 2016-11-18.
"Early Intervention – National Down Syndrome Society". www.ndss.org. Archived from the original on 2016-11-19. Retrieved 2016-11-18.
"European Down Syndrome Association news" (PDF). European Down Syndrome Association. 2006. Archived from the original (PDF) on 22 February 2014. Retrieved 7 February 2014.
"Number of 14- through 21-year-old students served under Individuals with Disabilities Education Act, Part B, who exited school, by exit reason, age, and type of disability: 2007–08 and 2008–09". National Center for Education Statistics. Archived from the original on 22 February 2014. Retrieved 7 February 2014.
"Down's Syndrome: Employment Barriers". Rehab Care International. Archived from the original on 22 February 2014. Retrieved 7 February 2014.
Urbano R (9 September 2010). Health Issues Among Persons With Down Syndrome. Academic Press. p. 108. ISBN 978-0-12-374477-7. Archived from the original on 12 May 2015.
"Where Should I Go From Here?". National Down Syndrome Society. Archived from the original on 22 December 2015. Retrieved 19 December 2015.
Fisch H (2013). "The male biological clock". In Carrell DT (ed.). Paternal influences on human reproductive success. Cambridge University Press. p. 65. ISBN 978-1-107-02448-9. Archived from the original on 2017-01-23.
Down JL (1866). "Observations on an ethnic classification of idiots". Clinical Lecture Reports, London Hospital. 3: 259–62. Archived from the original on 2006-06-15. Retrieved 2006-07-14.
Wright D (25 August 2011). Downs: The history of a disability. Oxford University Press. pp. 104–108. ISBN 978-0-19-956793-5. Archived from the original on 28 May 2013. Retrieved 25 August 2012.
Wright D (25 August 2011). Downs: The history of a disability. Oxford University Press. p. 145. ISBN 978-0-19-956793-5. Archived from the original on 28 May 2013. Retrieved 25 August 2012.
Gautier M, Harper PS (2009). "Fiftieth anniversary of trisomy 21: returning to a discovery" (PDF). Human Genetics. 126 (2): 317–324. doi:10.1007/s00439-009-0690-1. S2CID 30299551. Archived (PDF) from the original on 2017-02-02.
Wright D (25 August 2011). Downs: The history of a disability. Oxford University Press. pp. 9–10. ISBN 978-0-19-956793-5. Archived from the original on 28 May 2013. Retrieved 25 August 2012.
"Halifax mom questions Down syndrome suppression". Archived from the original on 2015-11-05. Retrieved 2015-09-26.
Belkin L (2010-01-11). "Should Down Syndrome Be Cured?". Archived from the original on 2015-04-25. Retrieved 2015-09-26.
Leonard BJ, Crainshaw JY (2013). Encyclopedia of religious controversies in the United States (2nd ed.). Santa Barbara, Calif.: ABC-CLIO. p. 278. ISBN 978-1-59884-867-0. Archived from the original on 2017-01-23.
Shields SG, Candib LM (2010). Woman-centered care in pregnancy and childbirth. Oxford: Radcliffe Pub. p. 140. ISBN 978-1-84619-161-9. Archived from the original on 2017-01-23.
Wright D (2011). "Into the Mainstream". Downs: The history of a disability. Oxford University Press. p. 147. ISBN 978-0-19-161978-6. Archived from the original on 2017-01-23.
"Timeline". MENCAP. Archived from the original on 17 June 2011. Retrieved 2 February 2014.
"National Down Syndrome Organizations in the U.S." Global Down Syndrome Foundation. 2012-02-21. Archived from the original on 18 January 2014. Retrieved 2 February 2014.
"World Down Syndrome Day". Down Syndrome International. Archived from the original on 14 March 2014. Retrieved 2 February 2014.
Pratt G, Rosner V (2012). The global and the intimate feminism in our time. New York: Columbia University Press. p. 113. ISBN 978-0-231-52084-3. Archived from the original on 2017-01-23.
"Life Goes On Actor Chris Burke on Being the First Primetime Television Star with Down Syndrome". Oprah.com. Archived from the original on 14 August 2015. Retrieved 2023-04-01.