Interleukin 15 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Interleukin 15" in English language version.

refsWebsite

Global rank English rank

61nih.gov

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42doi.org

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10semanticscholar.org

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6harvard.edu

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2ensembl.org

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2web.archive.org

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2sotio.com

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1zenodo.org

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1bham.ac.uk

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1webmd.com

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1clinicaltrials.gov

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1altorbioscience.com

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altorbioscience.com

"Altor BioScience". altorbioscience.com. Archived from the original on 2018-11-09. Retrieved 2018-11-08.

bham.ac.uk

pure-oai.bham.ac.uk

Pérez-López A, McKendry J, Martin-Rincon M, Morales-Alamo D, Pérez-Köhler B, Valadés D, et al. (January 2018). "Skeletal muscle IL-15/IL-15Rα and myofibrillar protein synthesis after resistance exercise" (PDF). Scandinavian Journal of Medicine & Science in Sports. 28 (1): 116–125. doi:10.1111/sms.12901. PMID 28449327. S2CID 41641289.

clinicaltrials.gov

"A Phase I Study of Intravenous Recombinant Human IL-15 in Adults With Refractory Metastatic Malignant Melanoma and Metastatic Renal Cell Cancer". ClinicalTrials. 7 November 2019.

doi.org

Steel JC, Waldmann TA, Morris JC (January 2012). "Interleukin-15 biology and its therapeutic implications in cancer". Trends in Pharmacological Sciences. 33 (1): 35–41. doi:10.1016/j.tips.2011.09.004. PMC 3327885. PMID 22032984.
Di Sabatino A, Calarota SA, Vidali F, Macdonald TT, Corazza GR (February 2011). "Role of IL-15 in immune-mediated and infectious diseases". Cytokine & Growth Factor Reviews. 22 (1): 19–33. doi:10.1016/j.cytogfr.2010.09.003. PMID 21074481.
Grabstein KH, Eisenman J, Shanebeck K, Rauch C, Srinivasan S, Fung V, et al. (May 1994). "Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor". Science. 264 (5161): 965–968. Bibcode:1994Sci...264..965G. doi:10.1126/science.8178155. PMID 8178155.
Lodolce JP, Burkett PR, Koka RM, Boone DL, Ma A (December 2002). "Regulation of lymphoid homeostasis by interleukin-15". Cytokine & Growth Factor Reviews. 13 (6): 429–439. doi:10.1016/S1359-6101(02)00029-1. PMID 12401478.
Waldmann TA, Tagaya Y (1999). "The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens". Annual Review of Immunology. 17: 19–49. doi:10.1146/annurev.immunol.17.1.19. PMID 10358752.
Tagaya Y, Kurys G, Thies TA, Losi JM, Azimi N, Hanover JA, et al. (December 1997). "Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides". Proceedings of the National Academy of Sciences of the United States of America. 94 (26): 14444–14449. Bibcode:1997PNAS...9414444T. doi:10.1073/pnas.94.26.14444. PMC 25016. PMID 9405632.
Nishimura H, Yajima T, Naiki Y, Tsunobuchi H, Umemura M, Itano K, et al. (January 2000). "Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo". The Journal of Experimental Medicine. 191 (1): 157–170. doi:10.1084/jem.191.1.157. PMC 2195806. PMID 10620614.
Jakobisiak M, Golab J, Lasek W (April 2011). "Interleukin 15 as a promising candidate for tumor immunotherapy". Cytokine & Growth Factor Reviews. 22 (2): 99–108. doi:10.1016/j.cytogfr.2011.04.001. PMID 21531164.
Bamford RN, DeFilippis AP, Azimi N, Kurys G, Waldmann TA (May 1998). "The 5' untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control". Journal of Immunology. 160 (9): 4418–4426. doi:10.4049/jimmunol.160.9.4418. PMID 9574546. S2CID 21887678.
Olsen SK, Ota N, Kishishita S, Kukimoto-Niino M, Murayama K, Uchiyama H, et al. (December 2007). "Crystal Structure of the interleukin-15.interleukin-15 receptor alpha complex: insights into trans and cis presentation". The Journal of Biological Chemistry. 282 (51): 37191–37204. doi:10.1074/jbc.M706150200. PMID 17947230.
Okada S, Han S, Patel ES, Yang LJ, Chang LJ (2015). "STAT3 signaling contributes to the high effector activities of interleukin-15-derived dendritic cells". Immunology and Cell Biology. 93 (5): 461–471. doi:10.1038/icb.2014.103. PMC 4450366. PMID 25582338.
Schluns KS, Stoklasek T, Lefrançois L (August 2005). "The roles of interleukin-15 receptor alpha: trans-presentation, receptor component, or both?". The International Journal of Biochemistry & Cell Biology. 37 (8): 1567–1571. doi:10.1016/j.biocel.2005.02.017. PMID 15896666.
Perera PY, Lichy JH, Waldmann TA, Perera LP (March 2012). "The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use". Microbes and Infection. 14 (3): 247–261. doi:10.1016/j.micinf.2011.10.006. PMC 3270128. PMID 22064066.
Malamut G, El Machhour R, Montcuquet N, Martin-Lannerée S, Dusanter-Fourt I, Verkarre V, et al. (June 2010). "IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis". The Journal of Clinical Investigation. 120 (6): 2131–2143. doi:10.1172/JCI41344. PMC 2877946. PMID 20440074.
Pedersen BK (January 2011). "Muscles and their myokines". The Journal of Experimental Biology. 214 (Pt 2): 337–346. doi:10.1242/jeb.048074. PMID 21177953.
Pérez-López A, Valadés D, Vázquez Martínez C, de Cos Blanco AI, Bujan J, García-Honduvilla N (March 2018). "Serum IL-15 and IL-15Rα levels are decreased in lean and obese physically active humans". Scandinavian Journal of Medicine & Science in Sports. 28 (3): 1113–1120. doi:10.1111/sms.12983. PMID 28940555. S2CID 3526909.
Pérez-López A, McKendry J, Martin-Rincon M, Morales-Alamo D, Pérez-Köhler B, Valadés D, et al. (January 2018). "Skeletal muscle IL-15/IL-15Rα and myofibrillar protein synthesis after resistance exercise" (PDF). Scandinavian Journal of Medicine & Science in Sports. 28 (1): 116–125. doi:10.1111/sms.12901. PMID 28449327. S2CID 41641289.
Dijkstra JM (February 2021). "A method for making alignments of related protein sequences that share very little similarity; shark interleukin 2 as an example". Immunogenetics. 73 (1): 35–51. doi:10.1007/s00251-020-01191-5. PMID 33512550. S2CID 231770873.
Wang T, Holland JW, Carrington A, Zou J, Secombes CJ (August 2007). "Molecular and functional characterization of IL-15 in rainbow trout Oncorhynchus mykiss: a potent inducer of IFN-gamma expression in spleen leukocytes". Journal of Immunology. 179 (3): 1475–1488. doi:10.4049/jimmunol.179.3.1475. PMID 17641013. S2CID 45106342.
Yamaguchi T, Chang CJ, Karger A, Keller M, Pfaff F, Wangkahart E, et al. (2020-10-29). "Ancient Cytokine Interleukin 15-Like (IL-15L) Induces a Type 2 Immune Response". Frontiers in Immunology. 11: 549319. doi:10.3389/fimmu.2020.549319. PMC 7658486. PMID 33193315.
Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, et al. (December 1995). "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". The Journal of Biological Chemistry. 270 (50): 29862–29869. doi:10.1074/jbc.270.50.29862. PMID 8530383.
Dijkstra JM, Takizawa F, Fischer U, Friedrich M, Soto-Lampe V, Lefèvre C, et al. (February 2014). "Identification of a gene for an ancient cytokine, interleukin 15-like, in mammals; interleukins 2 and 15 co-evolved with this third family member, all sharing binding motifs for IL-15Rα". Immunogenetics. 66 (2): 93–103. doi:10.1007/s00251-013-0747-0. PMC 3894449. PMID 24276591.
Wen Y, Fang W, Xiang LX, Pan RL, Shao JZ (August 2011). "Identification of Treg-like cells in Tetraodon: insight into the origin of regulatory T subsets during early vertebrate evolution". Cellular and Molecular Life Sciences. 68 (15): 2615–2626. doi:10.1007/s00018-010-0574-5. PMC 11115099. PMID 21063894. S2CID 22936159.
Wang J, Wang W, Xu J, Jia Z, Liu Q, Zhu X, et al. (February 2021). "Structural insights into the co-evolution of IL-2 and its private receptor in fish". Developmental and Comparative Immunology. 115: 103895. doi:10.1016/j.dci.2020.103895. PMID 33065202. S2CID 223557924.
Fang W, Shao JZ, Xiang LX (July 2007). "Molecular cloning and characterization of IL-15R alpha gene in rainbow trout (Oncorhynchus mykiss)". Fish & Shellfish Immunology. 23 (1): 119–127. doi:10.1016/j.fsi.2006.09.011. PMID 17101279.
Wang W, Wang J, Lei L, Xu J, Qin Y, Gao Q, Zou J (December 2020). "Characterisation of IL-15 and IL-2Rβ in grass carp: IL-15 upregulates cytokines and transcription factors of type 1 immune response and NK cell activation". Fish & Shellfish Immunology. 107 (Pt A): 104–117. doi:10.1016/j.fsi.2020.09.029. PMID 32971272. S2CID 221917064.
Sauce D, Larsen M, Curnow SJ, Leese AM, Moss PA, Hislop AD, et al. (July 2006). "EBV-associated mononucleosis leads to long-term global deficit in T-cell responsiveness to IL-15". Blood. 108 (1): 11–18. doi:10.1182/blood-2006-01-0144. PMID 16543467.
DePaolo RW, Abadie V, Tang F, Fehlner-Peach H, Hall JA, Wang W, et al. (March 2011). "Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens". Nature. 471 (7337): 220–224. Bibcode:2011Natur.471..220D. doi:10.1038/nature09849. PMC 3076739. PMID 21307853.
- Denise Mann; Laura J. Martin (February 8, 2011). "New Treatment for Celiac Disease?". WebMD.
- Yokoyama S, Watanabe N, Sato N, Perera PY, Filkoski L, Tanaka T, et al. (September 2009). "Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes". Proceedings of the National Academy of Sciences of the United States of America. 106 (37): 15849–15854. Bibcode:2009PNAS..10615849Y. doi:10.1073/pnas.0908834106. PMC 2736142. PMID 19805228.
- Cepero-Donates Y, Lacraz G, Ghobadi F, Rakotoarivelo V, Orkhis S, Mayhue M, et al. (June 2016). "Interleukin-15-mediated inflammation promotes non-alcoholic fatty liver disease". Cytokine. 82: 102–111. doi:10.1016/j.cyto.2016.01.020. PMID 26868085.
- Baslund B, Tvede N, Danneskiold-Samsoe B, Larsson P, Panayi G, Petersen J, et al. (September 2005). "Targeting interleukin-15 in patients with rheumatoid arthritis: a proof-of-concept study". Arthritis and Rheumatism. 52 (9): 2686–2692. doi:10.1002/art.21249. PMID 16142748.
- Klebanoff CA, Finkelstein SE, Surman DR, Lichtman MK, Gattinoni L, Theoret MR, et al. (February 2004). "IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells". Proceedings of the National Academy of Sciences of the United States of America. 101 (7): 1969–1974. Bibcode:2004PNAS..101.1969K. doi:10.1073/pnas.0307298101. PMC 357036. PMID 14762166.
- Teague RM, Sather BD, Sacks JA, Huang MZ, Dossett ML, Morimoto J, et al. (March 2006). "Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors". Nature Medicine. 12 (3): 335–341. doi:10.1038/nm1359. PMID 16474399. S2CID 44396600.
- Xu X, Sun Q, Yu X, Zhao L (April 2017). "Rescue of nonlytic Newcastle Disease Virus (NDV) expressing IL-15 for cancer immunotherapy". Virus Research. 233: 35–41. doi:10.1016/j.virusres.2017.03.003. PMID 28286036.
- Valkenburg SA, Li OT, Mak PW, Mok CK, Nicholls JM, Guan Y, et al. (April 2014). "IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection". Proceedings of the National Academy of Sciences of the United States of America. 111 (15): 5676–5681. Bibcode:2014PNAS..111.5676V. doi:10.1073/pnas.1403684111. PMC 3992686. PMID 24706798.
- Hu XD, Chen ST, Li JY, Yu DH, Cai H (March 2010). "An IL-15 adjuvant enhances the efficacy of a combined DNA vaccine against Brucella by increasing the CD8+ cytotoxic T cell response". Vaccine. 28 (12): 2408–2415. doi:10.1016/j.vaccine.2009.12.076. PMID 20064480.
- Hock K, Laengle J, Kuznetsova I, Egorov A, Hegedus B, Dome B, et al. (March 2017). "Oncolytic influenza A virus expressing interleukin-15 decreases tumor growth in vivo". Surgery. 161 (3): 735–746. doi:10.1016/j.surg.2016.08.045. PMID 27776794. S2CID 21802215.
- Ahmad A, Ahmad R, Iannello A, Toma E, Morisset R, Sindhu ST (July 2005). "IL-15 and HIV infection: lessons for immunotherapy and vaccination". Current HIV Research. 3 (3): 261–270. doi:10.2174/1570162054368093. PMID 16022657.
- Suck G, Oei VY, Linn YC, Ho SH, Chu S, Choong A, et al. (September 2011). "Interleukin-15 supports generation of highly potent clinical-grade natural killer cells in long-term cultures for targeting hematological malignancies". Experimental Hematology. 39 (9): 904–914. doi:10.1016/j.exphem.2011.06.003. PMID 21703984.
- Guo Y, Luan L, Patil NK, Wang J, Bohannon JK, Rabacal W, et al. (February 2017). "IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function". Journal of Immunology. 198 (3): 1320–1333. doi:10.4049/jimmunol.1601486. PMC 5263185. PMID 28031340.
- Liu B, Kong L, Han K, Hong H, Marcus WD, Chen X, et al. (November 2016). "A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses". The Journal of Biological Chemistry. 291 (46): 23869–23881. doi:10.1074/jbc.M116.733600. PMC 5104912. PMID 27650494.
- Robinson TO, Schluns KS (October 2017). "The potential and promise of IL-15 in immuno-oncogenic therapies". Immunology Letters. 190: 159–168. doi:10.1016/j.imlet.2017.08.010. PMC 5774016. PMID 28823521.

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000164136 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000031712 – Ensembl, May 2017

harvard.edu

ui.adsabs.harvard.edu

Grabstein KH, Eisenman J, Shanebeck K, Rauch C, Srinivasan S, Fung V, et al. (May 1994). "Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor". Science. 264 (5161): 965–968. Bibcode:1994Sci...264..965G. doi:10.1126/science.8178155. PMID 8178155.
Tagaya Y, Kurys G, Thies TA, Losi JM, Azimi N, Hanover JA, et al. (December 1997). "Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides". Proceedings of the National Academy of Sciences of the United States of America. 94 (26): 14444–14449. Bibcode:1997PNAS...9414444T. doi:10.1073/pnas.94.26.14444. PMC 25016. PMID 9405632.
DePaolo RW, Abadie V, Tang F, Fehlner-Peach H, Hall JA, Wang W, et al. (March 2011). "Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens". Nature. 471 (7337): 220–224. Bibcode:2011Natur.471..220D. doi:10.1038/nature09849. PMC 3076739. PMID 21307853.
- Denise Mann; Laura J. Martin (February 8, 2011). "New Treatment for Celiac Disease?". WebMD.
- Yokoyama S, Watanabe N, Sato N, Perera PY, Filkoski L, Tanaka T, et al. (September 2009). "Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes". Proceedings of the National Academy of Sciences of the United States of America. 106 (37): 15849–15854. Bibcode:2009PNAS..10615849Y. doi:10.1073/pnas.0908834106. PMC 2736142. PMID 19805228.
- Klebanoff CA, Finkelstein SE, Surman DR, Lichtman MK, Gattinoni L, Theoret MR, et al. (February 2004). "IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells". Proceedings of the National Academy of Sciences of the United States of America. 101 (7): 1969–1974. Bibcode:2004PNAS..101.1969K. doi:10.1073/pnas.0307298101. PMC 357036. PMID 14762166.
- Valkenburg SA, Li OT, Mak PW, Mok CK, Nicholls JM, Guan Y, et al. (April 2014). "IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection". Proceedings of the National Academy of Sciences of the United States of America. 111 (15): 5676–5681. Bibcode:2014PNAS..111.5676V. doi:10.1073/pnas.1403684111. PMC 3992686. PMID 24706798.

nih.gov

pubmed.ncbi.nlm.nih.gov

Steel JC, Waldmann TA, Morris JC (January 2012). "Interleukin-15 biology and its therapeutic implications in cancer". Trends in Pharmacological Sciences. 33 (1): 35–41. doi:10.1016/j.tips.2011.09.004. PMC 3327885. PMID 22032984.
Di Sabatino A, Calarota SA, Vidali F, Macdonald TT, Corazza GR (February 2011). "Role of IL-15 in immune-mediated and infectious diseases". Cytokine & Growth Factor Reviews. 22 (1): 19–33. doi:10.1016/j.cytogfr.2010.09.003. PMID 21074481.
Grabstein KH, Eisenman J, Shanebeck K, Rauch C, Srinivasan S, Fung V, et al. (May 1994). "Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor". Science. 264 (5161): 965–968. Bibcode:1994Sci...264..965G. doi:10.1126/science.8178155. PMID 8178155.
Lodolce JP, Burkett PR, Koka RM, Boone DL, Ma A (December 2002). "Regulation of lymphoid homeostasis by interleukin-15". Cytokine & Growth Factor Reviews. 13 (6): 429–439. doi:10.1016/S1359-6101(02)00029-1. PMID 12401478.
Waldmann TA, Tagaya Y (1999). "The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens". Annual Review of Immunology. 17: 19–49. doi:10.1146/annurev.immunol.17.1.19. PMID 10358752.
Tagaya Y, Kurys G, Thies TA, Losi JM, Azimi N, Hanover JA, et al. (December 1997). "Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides". Proceedings of the National Academy of Sciences of the United States of America. 94 (26): 14444–14449. Bibcode:1997PNAS...9414444T. doi:10.1073/pnas.94.26.14444. PMC 25016. PMID 9405632.
Nishimura H, Yajima T, Naiki Y, Tsunobuchi H, Umemura M, Itano K, et al. (January 2000). "Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo". The Journal of Experimental Medicine. 191 (1): 157–170. doi:10.1084/jem.191.1.157. PMC 2195806. PMID 10620614.
Jakobisiak M, Golab J, Lasek W (April 2011). "Interleukin 15 as a promising candidate for tumor immunotherapy". Cytokine & Growth Factor Reviews. 22 (2): 99–108. doi:10.1016/j.cytogfr.2011.04.001. PMID 21531164.
Bamford RN, DeFilippis AP, Azimi N, Kurys G, Waldmann TA (May 1998). "The 5' untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control". Journal of Immunology. 160 (9): 4418–4426. doi:10.4049/jimmunol.160.9.4418. PMID 9574546. S2CID 21887678.
Olsen SK, Ota N, Kishishita S, Kukimoto-Niino M, Murayama K, Uchiyama H, et al. (December 2007). "Crystal Structure of the interleukin-15.interleukin-15 receptor alpha complex: insights into trans and cis presentation". The Journal of Biological Chemistry. 282 (51): 37191–37204. doi:10.1074/jbc.M706150200. PMID 17947230.
Okada S, Han S, Patel ES, Yang LJ, Chang LJ (2015). "STAT3 signaling contributes to the high effector activities of interleukin-15-derived dendritic cells". Immunology and Cell Biology. 93 (5): 461–471. doi:10.1038/icb.2014.103. PMC 4450366. PMID 25582338.
Schluns KS, Stoklasek T, Lefrançois L (August 2005). "The roles of interleukin-15 receptor alpha: trans-presentation, receptor component, or both?". The International Journal of Biochemistry & Cell Biology. 37 (8): 1567–1571. doi:10.1016/j.biocel.2005.02.017. PMID 15896666.
Perera PY, Lichy JH, Waldmann TA, Perera LP (March 2012). "The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use". Microbes and Infection. 14 (3): 247–261. doi:10.1016/j.micinf.2011.10.006. PMC 3270128. PMID 22064066.
Malamut G, El Machhour R, Montcuquet N, Martin-Lannerée S, Dusanter-Fourt I, Verkarre V, et al. (June 2010). "IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis". The Journal of Clinical Investigation. 120 (6): 2131–2143. doi:10.1172/JCI41344. PMC 2877946. PMID 20440074.
Pedersen BK (January 2011). "Muscles and their myokines". The Journal of Experimental Biology. 214 (Pt 2): 337–346. doi:10.1242/jeb.048074. PMID 21177953.
Pérez-López A, Valadés D, Vázquez Martínez C, de Cos Blanco AI, Bujan J, García-Honduvilla N (March 2018). "Serum IL-15 and IL-15Rα levels are decreased in lean and obese physically active humans". Scandinavian Journal of Medicine & Science in Sports. 28 (3): 1113–1120. doi:10.1111/sms.12983. PMID 28940555. S2CID 3526909.
Pérez-López A, McKendry J, Martin-Rincon M, Morales-Alamo D, Pérez-Köhler B, Valadés D, et al. (January 2018). "Skeletal muscle IL-15/IL-15Rα and myofibrillar protein synthesis after resistance exercise" (PDF). Scandinavian Journal of Medicine & Science in Sports. 28 (1): 116–125. doi:10.1111/sms.12901. PMID 28449327. S2CID 41641289.
Dijkstra JM (February 2021). "A method for making alignments of related protein sequences that share very little similarity; shark interleukin 2 as an example". Immunogenetics. 73 (1): 35–51. doi:10.1007/s00251-020-01191-5. PMID 33512550. S2CID 231770873.
Wang T, Holland JW, Carrington A, Zou J, Secombes CJ (August 2007). "Molecular and functional characterization of IL-15 in rainbow trout Oncorhynchus mykiss: a potent inducer of IFN-gamma expression in spleen leukocytes". Journal of Immunology. 179 (3): 1475–1488. doi:10.4049/jimmunol.179.3.1475. PMID 17641013. S2CID 45106342.
Yamaguchi T, Chang CJ, Karger A, Keller M, Pfaff F, Wangkahart E, et al. (2020-10-29). "Ancient Cytokine Interleukin 15-Like (IL-15L) Induces a Type 2 Immune Response". Frontiers in Immunology. 11: 549319. doi:10.3389/fimmu.2020.549319. PMC 7658486. PMID 33193315.
Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, et al. (December 1995). "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". The Journal of Biological Chemistry. 270 (50): 29862–29869. doi:10.1074/jbc.270.50.29862. PMID 8530383.
Dijkstra JM, Takizawa F, Fischer U, Friedrich M, Soto-Lampe V, Lefèvre C, et al. (February 2014). "Identification of a gene for an ancient cytokine, interleukin 15-like, in mammals; interleukins 2 and 15 co-evolved with this third family member, all sharing binding motifs for IL-15Rα". Immunogenetics. 66 (2): 93–103. doi:10.1007/s00251-013-0747-0. PMC 3894449. PMID 24276591.
Wen Y, Fang W, Xiang LX, Pan RL, Shao JZ (August 2011). "Identification of Treg-like cells in Tetraodon: insight into the origin of regulatory T subsets during early vertebrate evolution". Cellular and Molecular Life Sciences. 68 (15): 2615–2626. doi:10.1007/s00018-010-0574-5. PMC 11115099. PMID 21063894. S2CID 22936159.
Wang J, Wang W, Xu J, Jia Z, Liu Q, Zhu X, et al. (February 2021). "Structural insights into the co-evolution of IL-2 and its private receptor in fish". Developmental and Comparative Immunology. 115: 103895. doi:10.1016/j.dci.2020.103895. PMID 33065202. S2CID 223557924.
Fang W, Shao JZ, Xiang LX (July 2007). "Molecular cloning and characterization of IL-15R alpha gene in rainbow trout (Oncorhynchus mykiss)". Fish & Shellfish Immunology. 23 (1): 119–127. doi:10.1016/j.fsi.2006.09.011. PMID 17101279.
Wang W, Wang J, Lei L, Xu J, Qin Y, Gao Q, Zou J (December 2020). "Characterisation of IL-15 and IL-2Rβ in grass carp: IL-15 upregulates cytokines and transcription factors of type 1 immune response and NK cell activation". Fish & Shellfish Immunology. 107 (Pt A): 104–117. doi:10.1016/j.fsi.2020.09.029. PMID 32971272. S2CID 221917064.
Sauce D, Larsen M, Curnow SJ, Leese AM, Moss PA, Hislop AD, et al. (July 2006). "EBV-associated mononucleosis leads to long-term global deficit in T-cell responsiveness to IL-15". Blood. 108 (1): 11–18. doi:10.1182/blood-2006-01-0144. PMID 16543467.
DePaolo RW, Abadie V, Tang F, Fehlner-Peach H, Hall JA, Wang W, et al. (March 2011). "Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens". Nature. 471 (7337): 220–224. Bibcode:2011Natur.471..220D. doi:10.1038/nature09849. PMC 3076739. PMID 21307853.
- Denise Mann; Laura J. Martin (February 8, 2011). "New Treatment for Celiac Disease?". WebMD.
- Yokoyama S, Watanabe N, Sato N, Perera PY, Filkoski L, Tanaka T, et al. (September 2009). "Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes". Proceedings of the National Academy of Sciences of the United States of America. 106 (37): 15849–15854. Bibcode:2009PNAS..10615849Y. doi:10.1073/pnas.0908834106. PMC 2736142. PMID 19805228.
- Cepero-Donates Y, Lacraz G, Ghobadi F, Rakotoarivelo V, Orkhis S, Mayhue M, et al. (June 2016). "Interleukin-15-mediated inflammation promotes non-alcoholic fatty liver disease". Cytokine. 82: 102–111. doi:10.1016/j.cyto.2016.01.020. PMID 26868085.
- Baslund B, Tvede N, Danneskiold-Samsoe B, Larsson P, Panayi G, Petersen J, et al. (September 2005). "Targeting interleukin-15 in patients with rheumatoid arthritis: a proof-of-concept study". Arthritis and Rheumatism. 52 (9): 2686–2692. doi:10.1002/art.21249. PMID 16142748.
- Klebanoff CA, Finkelstein SE, Surman DR, Lichtman MK, Gattinoni L, Theoret MR, et al. (February 2004). "IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells". Proceedings of the National Academy of Sciences of the United States of America. 101 (7): 1969–1974. Bibcode:2004PNAS..101.1969K. doi:10.1073/pnas.0307298101. PMC 357036. PMID 14762166.
- Teague RM, Sather BD, Sacks JA, Huang MZ, Dossett ML, Morimoto J, et al. (March 2006). "Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors". Nature Medicine. 12 (3): 335–341. doi:10.1038/nm1359. PMID 16474399. S2CID 44396600.
- Xu X, Sun Q, Yu X, Zhao L (April 2017). "Rescue of nonlytic Newcastle Disease Virus (NDV) expressing IL-15 for cancer immunotherapy". Virus Research. 233: 35–41. doi:10.1016/j.virusres.2017.03.003. PMID 28286036.
- Valkenburg SA, Li OT, Mak PW, Mok CK, Nicholls JM, Guan Y, et al. (April 2014). "IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection". Proceedings of the National Academy of Sciences of the United States of America. 111 (15): 5676–5681. Bibcode:2014PNAS..111.5676V. doi:10.1073/pnas.1403684111. PMC 3992686. PMID 24706798.
- Hu XD, Chen ST, Li JY, Yu DH, Cai H (March 2010). "An IL-15 adjuvant enhances the efficacy of a combined DNA vaccine against Brucella by increasing the CD8+ cytotoxic T cell response". Vaccine. 28 (12): 2408–2415. doi:10.1016/j.vaccine.2009.12.076. PMID 20064480.
- Hock K, Laengle J, Kuznetsova I, Egorov A, Hegedus B, Dome B, et al. (March 2017). "Oncolytic influenza A virus expressing interleukin-15 decreases tumor growth in vivo". Surgery. 161 (3): 735–746. doi:10.1016/j.surg.2016.08.045. PMID 27776794. S2CID 21802215.
- Ahmad A, Ahmad R, Iannello A, Toma E, Morisset R, Sindhu ST (July 2005). "IL-15 and HIV infection: lessons for immunotherapy and vaccination". Current HIV Research. 3 (3): 261–270. doi:10.2174/1570162054368093. PMID 16022657.
- Suck G, Oei VY, Linn YC, Ho SH, Chu S, Choong A, et al. (September 2011). "Interleukin-15 supports generation of highly potent clinical-grade natural killer cells in long-term cultures for targeting hematological malignancies". Experimental Hematology. 39 (9): 904–914. doi:10.1016/j.exphem.2011.06.003. PMID 21703984.
- Guo Y, Luan L, Patil NK, Wang J, Bohannon JK, Rabacal W, et al. (February 2017). "IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function". Journal of Immunology. 198 (3): 1320–1333. doi:10.4049/jimmunol.1601486. PMC 5263185. PMID 28031340.
- Liu B, Kong L, Han K, Hong H, Marcus WD, Chen X, et al. (November 2016). "A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses". The Journal of Biological Chemistry. 291 (46): 23869–23881. doi:10.1074/jbc.M116.733600. PMC 5104912. PMID 27650494.
- Robinson TO, Schluns KS (October 2017). "The potential and promise of IL-15 in immuno-oncogenic therapies". Immunology Letters. 190: 159–168. doi:10.1016/j.imlet.2017.08.010. PMC 5774016. PMID 28823521.
ncbi.nlm.nih.gov
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Steel JC, Waldmann TA, Morris JC (January 2012). "Interleukin-15 biology and its therapeutic implications in cancer". Trends in Pharmacological Sciences. 33 (1): 35–41. doi:10.1016/j.tips.2011.09.004. PMC 3327885. PMID 22032984.
- "Entrez Gene: IL15 interleukin 15".
- Tagaya Y, Kurys G, Thies TA, Losi JM, Azimi N, Hanover JA, et al. (December 1997). "Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides". Proceedings of the National Academy of Sciences of the United States of America. 94 (26): 14444–14449. Bibcode:1997PNAS...9414444T. doi:10.1073/pnas.94.26.14444. PMC 25016. PMID 9405632.
- Nishimura H, Yajima T, Naiki Y, Tsunobuchi H, Umemura M, Itano K, et al. (January 2000). "Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo". The Journal of Experimental Medicine. 191 (1): 157–170. doi:10.1084/jem.191.1.157. PMC 2195806. PMID 10620614.
- Okada S, Han S, Patel ES, Yang LJ, Chang LJ (2015). "STAT3 signaling contributes to the high effector activities of interleukin-15-derived dendritic cells". Immunology and Cell Biology. 93 (5): 461–471. doi:10.1038/icb.2014.103. PMC 4450366. PMID 25582338.
- Perera PY, Lichy JH, Waldmann TA, Perera LP (March 2012). "The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use". Microbes and Infection. 14 (3): 247–261. doi:10.1016/j.micinf.2011.10.006. PMC 3270128. PMID 22064066.
- Malamut G, El Machhour R, Montcuquet N, Martin-Lannerée S, Dusanter-Fourt I, Verkarre V, et al. (June 2010). "IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis". The Journal of Clinical Investigation. 120 (6): 2131–2143. doi:10.1172/JCI41344. PMC 2877946. PMID 20440074.
- Yamaguchi T, Chang CJ, Karger A, Keller M, Pfaff F, Wangkahart E, et al. (2020-10-29). "Ancient Cytokine Interleukin 15-Like (IL-15L) Induces a Type 2 Immune Response". Frontiers in Immunology. 11: 549319. doi:10.3389/fimmu.2020.549319. PMC 7658486. PMID 33193315.
- Dijkstra JM, Takizawa F, Fischer U, Friedrich M, Soto-Lampe V, Lefèvre C, et al. (February 2014). "Identification of a gene for an ancient cytokine, interleukin 15-like, in mammals; interleukins 2 and 15 co-evolved with this third family member, all sharing binding motifs for IL-15Rα". Immunogenetics. 66 (2): 93–103. doi:10.1007/s00251-013-0747-0. PMC 3894449. PMID 24276591.
- Wen Y, Fang W, Xiang LX, Pan RL, Shao JZ (August 2011). "Identification of Treg-like cells in Tetraodon: insight into the origin of regulatory T subsets during early vertebrate evolution". Cellular and Molecular Life Sciences. 68 (15): 2615–2626. doi:10.1007/s00018-010-0574-5. PMC 11115099. PMID 21063894. S2CID 22936159.
- DePaolo RW, Abadie V, Tang F, Fehlner-Peach H, Hall JA, Wang W, et al. (March 2011). "Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens". Nature. 471 (7337): 220–224. Bibcode:2011Natur.471..220D. doi:10.1038/nature09849. PMC 3076739. PMID 21307853.
  - Denise Mann; Laura J. Martin (February 8, 2011). "New Treatment for Celiac Disease?". WebMD.
  - Yokoyama S, Watanabe N, Sato N, Perera PY, Filkoski L, Tanaka T, et al. (September 2009). "Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes". Proceedings of the National Academy of Sciences of the United States of America. 106 (37): 15849–15854. Bibcode:2009PNAS..10615849Y. doi:10.1073/pnas.0908834106. PMC 2736142. PMID 19805228.
  - Klebanoff CA, Finkelstein SE, Surman DR, Lichtman MK, Gattinoni L, Theoret MR, et al. (February 2004). "IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells". Proceedings of the National Academy of Sciences of the United States of America. 101 (7): 1969–1974. Bibcode:2004PNAS..101.1969K. doi:10.1073/pnas.0307298101. PMC 357036. PMID 14762166.
  - Valkenburg SA, Li OT, Mak PW, Mok CK, Nicholls JM, Guan Y, et al. (April 2014). "IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection". Proceedings of the National Academy of Sciences of the United States of America. 111 (15): 5676–5681. Bibcode:2014PNAS..111.5676V. doi:10.1073/pnas.1403684111. PMC 3992686. PMID 24706798.
  - Guo Y, Luan L, Patil NK, Wang J, Bohannon JK, Rabacal W, et al. (February 2017). "IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function". Journal of Immunology. 198 (3): 1320–1333. doi:10.4049/jimmunol.1601486. PMC 5263185. PMID 28031340.
  - Liu B, Kong L, Han K, Hong H, Marcus WD, Chen X, et al. (November 2016). "A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses". The Journal of Biological Chemistry. 291 (46): 23869–23881. doi:10.1074/jbc.M116.733600. PMC 5104912. PMID 27650494.
  - Robinson TO, Schluns KS (October 2017). "The potential and promise of IL-15 in immuno-oncogenic therapies". Immunology Letters. 190: 159–168. doi:10.1016/j.imlet.2017.08.010. PMC 5774016. PMID 28823521.

semanticscholar.org

api.semanticscholar.org

Bamford RN, DeFilippis AP, Azimi N, Kurys G, Waldmann TA (May 1998). "The 5' untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control". Journal of Immunology. 160 (9): 4418–4426. doi:10.4049/jimmunol.160.9.4418. PMID 9574546. S2CID 21887678.
Pérez-López A, Valadés D, Vázquez Martínez C, de Cos Blanco AI, Bujan J, García-Honduvilla N (March 2018). "Serum IL-15 and IL-15Rα levels are decreased in lean and obese physically active humans". Scandinavian Journal of Medicine & Science in Sports. 28 (3): 1113–1120. doi:10.1111/sms.12983. PMID 28940555. S2CID 3526909.
Pérez-López A, McKendry J, Martin-Rincon M, Morales-Alamo D, Pérez-Köhler B, Valadés D, et al. (January 2018). "Skeletal muscle IL-15/IL-15Rα and myofibrillar protein synthesis after resistance exercise" (PDF). Scandinavian Journal of Medicine & Science in Sports. 28 (1): 116–125. doi:10.1111/sms.12901. PMID 28449327. S2CID 41641289.
Dijkstra JM (February 2021). "A method for making alignments of related protein sequences that share very little similarity; shark interleukin 2 as an example". Immunogenetics. 73 (1): 35–51. doi:10.1007/s00251-020-01191-5. PMID 33512550. S2CID 231770873.
Wang T, Holland JW, Carrington A, Zou J, Secombes CJ (August 2007). "Molecular and functional characterization of IL-15 in rainbow trout Oncorhynchus mykiss: a potent inducer of IFN-gamma expression in spleen leukocytes". Journal of Immunology. 179 (3): 1475–1488. doi:10.4049/jimmunol.179.3.1475. PMID 17641013. S2CID 45106342.
Wen Y, Fang W, Xiang LX, Pan RL, Shao JZ (August 2011). "Identification of Treg-like cells in Tetraodon: insight into the origin of regulatory T subsets during early vertebrate evolution". Cellular and Molecular Life Sciences. 68 (15): 2615–2626. doi:10.1007/s00018-010-0574-5. PMC 11115099. PMID 21063894. S2CID 22936159.
Wang J, Wang W, Xu J, Jia Z, Liu Q, Zhu X, et al. (February 2021). "Structural insights into the co-evolution of IL-2 and its private receptor in fish". Developmental and Comparative Immunology. 115: 103895. doi:10.1016/j.dci.2020.103895. PMID 33065202. S2CID 223557924.
Wang W, Wang J, Lei L, Xu J, Qin Y, Gao Q, Zou J (December 2020). "Characterisation of IL-15 and IL-2Rβ in grass carp: IL-15 upregulates cytokines and transcription factors of type 1 immune response and NK cell activation". Fish & Shellfish Immunology. 107 (Pt A): 104–117. doi:10.1016/j.fsi.2020.09.029. PMID 32971272. S2CID 221917064.
Teague RM, Sather BD, Sacks JA, Huang MZ, Dossett ML, Morimoto J, et al. (March 2006). "Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors". Nature Medicine. 12 (3): 335–341. doi:10.1038/nm1359. PMID 16474399. S2CID 44396600.
Hock K, Laengle J, Kuznetsova I, Egorov A, Hegedus B, Dome B, et al. (March 2017). "Oncolytic influenza A virus expressing interleukin-15 decreases tumor growth in vivo". Surgery. 161 (3): 735–746. doi:10.1016/j.surg.2016.08.045. PMID 27776794. S2CID 21802215.

sotio.com

"SO-C101 - Sotio". www.sotio.com. Archived from the original on 24 July 2019. Retrieved 16 August 2019.
"SOTIO initiates first-in-human clinical trial with IL-15 superagonist SO-C101". www.sotio.com. Retrieved 16 August 2019.

web.archive.org

"Altor BioScience". altorbioscience.com. Archived from the original on 2018-11-09. Retrieved 2018-11-08.
"SO-C101 - Sotio". www.sotio.com. Archived from the original on 24 July 2019. Retrieved 16 August 2019.

webmd.com

DePaolo RW, Abadie V, Tang F, Fehlner-Peach H, Hall JA, Wang W, et al. (March 2011). "Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens". Nature. 471 (7337): 220–224. Bibcode:2011Natur.471..220D. doi:10.1038/nature09849. PMC 3076739. PMID 21307853.
- Denise Mann; Laura J. Martin (February 8, 2011). "New Treatment for Celiac Disease?". WebMD.

zenodo.org

Waldmann TA, Tagaya Y (1999). "The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens". Annual Review of Immunology. 17: 19–49. doi:10.1146/annurev.immunol.17.1.19. PMID 10358752.