ROCK1 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "ROCK1" in English language version.

refsWebsite

Global rank English rank

29nih.gov

4^th place

17doi.org

2^nd place

4semanticscholar.org

11^th place

8^th place

2ensembl.org

1,626^th place

1,007^th place

1genecards.org

low place

1harvard.edu

18^th place

17^th place

1uniprot.org

5,673^rd place

6,418^th place

1physiology.org

5,293^rd place

7,651^st place

doi.org

Rath N, Olson MF (October 2012). "Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy". EMBO Reports. 13 (10): 900–8. doi:10.1038/embor.2012.127. PMC 3463970. PMID 22964758.
Hahmann C, Schroeter T (January 2010). "Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity". Cellular and Molecular Life Sciences. 67 (2): 171–7. doi:10.1007/s00018-009-0189-x. PMC 11115778. PMID 19907920. S2CID 6445354.
Riento K, Ridley AJ (June 2003). "Rocks: multifunctional kinases in cell behaviour". Nature Reviews Molecular Cell Biology. 4 (6): 446–56. doi:10.1038/nrm1128. PMID 12778124. S2CID 40665081.
Nakagawa O, Fujisawa K, Ishizaki T, Saito Y, Nakao K, Narumiya S (August 1996). "ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice". FEBS Letters. 392 (2): 189–93. doi:10.1016/0014-5793(96)00811-3. PMID 8772201. S2CID 6684411.
Jacobs M, Hayakawa K, Swenson L, Bellon S, Fleming M, Taslimi P, Doran J (January 2006). "The structure of dimeric ROCK I reveals the mechanism for ligand selectivity". The Journal of Biological Chemistry. 281 (1): 260–8. doi:10.1074/jbc.M508847200. PMID 16249185.
Truebestein L, Elsner DJ, Fuchs E, Leonard TA (2015-12-01). "A molecular ruler regulates cytoskeletal remodelling by the Rho kinases". Nature Communications. 6: 10029. Bibcode:2015NatCo...610029T. doi:10.1038/ncomms10029. PMC 4686654. PMID 26620183.
Feng J, Ito M, Kureishi Y, Ichikawa K, Amano M, Isaka N, Okawa K, Iwamatsu A, Kaibuchi K, Hartshorne DJ, Nakano T (February 1999). "Rho-associated kinase of chicken gizzard smooth muscle". The Journal of Biological Chemistry. 274 (6): 3744–52. doi:10.1074/jbc.274.6.3744. PMID 9920927.
Shirao S, Kashiwagi S, Sato M, Miwa S, Nakao F, Kurokawa T, Todoroki-Ikeda N, Mogami K, Mizukami Y, Kuriyama S, Haze K, Suzuki M, Kobayashi S (July 2002). "Sphingosylphosphorylcholine is a novel messenger for Rho-kinase-mediated Ca2+ sensitization in the bovine cerebral artery: unimportant role for protein kinase C". Circulation Research. 91 (2): 112–9. doi:10.1161/01.res.0000026057.13161.42. PMID 12142343.
Amano M, Fukata Y, Kaibuchi K (November 2000). "Regulation and functions of Rho-associated kinase". Experimental Cell Research. 261 (1): 44–51. doi:10.1006/excr.2000.5046. PMID 11082274.
Kroll, Jens; Epting, Daniel; Kern, Katrin; Dietz, Christian T.; Feng, Yuxi; Hammes, Hans-Peter; Wieland, Thomas; Augustin, Hellmut G. (2009). "Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis". American Journal of Physiology. Heart and Circulatory Physiology. 296 (3): H893–H899. doi:10.1152/ajpheart.01038.2008. PMID 19181962.
Da Silva JS, Medina M, Zuliani C, Di Nardo A, Witke W, Dotti CG (September 2003). "RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability". The Journal of Cell Biology. 162 (7): 1267–79. doi:10.1083/jcb.200304021. PMC 2173969. PMID 14517206.
Riento K, Guasch RM, Garg R, Jin B, Ridley AJ (June 2003). "RhoE binds to ROCK I and inhibits downstream signaling". Molecular and Cellular Biology. 23 (12): 4219–29. doi:10.1128/mcb.23.12.4219-4229.2003. PMC 156133. PMID 12773565.
Leung T, Chen XQ, Manser E, Lim L (October 1996). "The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton". Molecular and Cellular Biology. 16 (10): 5313–27. doi:10.1128/mcb.16.10.5313. PMC 231530. PMID 8816443.
Fujisawa K, Fujita A, Ishizaki T, Saito Y, Narumiya S (September 1996). "Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase". The Journal of Biological Chemistry. 271 (38): 23022–8. doi:10.1074/jbc.271.38.23022. PMID 8798490.
Croft DR, Sahai E, Mavria G, Li S, Tsai J, Lee WM, Marshall CJ, Olson MF (December 2004). "Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis". Cancer Research. 64 (24): 8994–9001. doi:10.1158/0008-5472.CAN-04-2052. PMID 15604264. S2CID 8380551.
Tönges L, Frank T, Tatenhorst L, Saal KA, Koch JC, Szego ÉM, Bähr M, Weishaupt JH, Lingor P (November 2012). "Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease". Brain. 135 (Pt 11): 3355–70. doi:10.1093/brain/aws254. PMC 3501973. PMID 23087045.
Dahal BK, Kosanovic D, Pamarthi PK, Sydykov A, Lai YJ, Kast R, Schirok H, Stasch JP, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Schermuly RT (October 2010). "Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension". The European Respiratory Journal. 36 (4): 808–18. doi:10.1183/09031936.00140309. PMID 20530035.

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000067900 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000024290 – Ensembl, May 2017

genecards.org

"Rho-Associated, Coiled-Coil Containing Protein Kinase 1".

harvard.edu

ui.adsabs.harvard.edu

Truebestein L, Elsner DJ, Fuchs E, Leonard TA (2015-12-01). "A molecular ruler regulates cytoskeletal remodelling by the Rho kinases". Nature Communications. 6: 10029. Bibcode:2015NatCo...610029T. doi:10.1038/ncomms10029. PMC 4686654. PMID 26620183.

nih.gov

pubmed.ncbi.nlm.nih.gov

Rath N, Olson MF (October 2012). "Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy". EMBO Reports. 13 (10): 900–8. doi:10.1038/embor.2012.127. PMC 3463970. PMID 22964758.
Hahmann C, Schroeter T (January 2010). "Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity". Cellular and Molecular Life Sciences. 67 (2): 171–7. doi:10.1007/s00018-009-0189-x. PMC 11115778. PMID 19907920. S2CID 6445354.
Riento K, Ridley AJ (June 2003). "Rocks: multifunctional kinases in cell behaviour". Nature Reviews Molecular Cell Biology. 4 (6): 446–56. doi:10.1038/nrm1128. PMID 12778124. S2CID 40665081.
Nakagawa O, Fujisawa K, Ishizaki T, Saito Y, Nakao K, Narumiya S (August 1996). "ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice". FEBS Letters. 392 (2): 189–93. doi:10.1016/0014-5793(96)00811-3. PMID 8772201. S2CID 6684411.
Jacobs M, Hayakawa K, Swenson L, Bellon S, Fleming M, Taslimi P, Doran J (January 2006). "The structure of dimeric ROCK I reveals the mechanism for ligand selectivity". The Journal of Biological Chemistry. 281 (1): 260–8. doi:10.1074/jbc.M508847200. PMID 16249185.
Truebestein L, Elsner DJ, Fuchs E, Leonard TA (2015-12-01). "A molecular ruler regulates cytoskeletal remodelling by the Rho kinases". Nature Communications. 6: 10029. Bibcode:2015NatCo...610029T. doi:10.1038/ncomms10029. PMC 4686654. PMID 26620183.
Feng J, Ito M, Kureishi Y, Ichikawa K, Amano M, Isaka N, Okawa K, Iwamatsu A, Kaibuchi K, Hartshorne DJ, Nakano T (February 1999). "Rho-associated kinase of chicken gizzard smooth muscle". The Journal of Biological Chemistry. 274 (6): 3744–52. doi:10.1074/jbc.274.6.3744. PMID 9920927.
Shirao S, Kashiwagi S, Sato M, Miwa S, Nakao F, Kurokawa T, Todoroki-Ikeda N, Mogami K, Mizukami Y, Kuriyama S, Haze K, Suzuki M, Kobayashi S (July 2002). "Sphingosylphosphorylcholine is a novel messenger for Rho-kinase-mediated Ca2+ sensitization in the bovine cerebral artery: unimportant role for protein kinase C". Circulation Research. 91 (2): 112–9. doi:10.1161/01.res.0000026057.13161.42. PMID 12142343.
Amano M, Fukata Y, Kaibuchi K (November 2000). "Regulation and functions of Rho-associated kinase". Experimental Cell Research. 261 (1): 44–51. doi:10.1006/excr.2000.5046. PMID 11082274.
Kroll, Jens; Epting, Daniel; Kern, Katrin; Dietz, Christian T.; Feng, Yuxi; Hammes, Hans-Peter; Wieland, Thomas; Augustin, Hellmut G. (2009). "Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis". American Journal of Physiology. Heart and Circulatory Physiology. 296 (3): H893–H899. doi:10.1152/ajpheart.01038.2008. PMID 19181962.
Da Silva JS, Medina M, Zuliani C, Di Nardo A, Witke W, Dotti CG (September 2003). "RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability". The Journal of Cell Biology. 162 (7): 1267–79. doi:10.1083/jcb.200304021. PMC 2173969. PMID 14517206.
Riento K, Guasch RM, Garg R, Jin B, Ridley AJ (June 2003). "RhoE binds to ROCK I and inhibits downstream signaling". Molecular and Cellular Biology. 23 (12): 4219–29. doi:10.1128/mcb.23.12.4219-4229.2003. PMC 156133. PMID 12773565.
Leung T, Chen XQ, Manser E, Lim L (October 1996). "The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton". Molecular and Cellular Biology. 16 (10): 5313–27. doi:10.1128/mcb.16.10.5313. PMC 231530. PMID 8816443.
Fujisawa K, Fujita A, Ishizaki T, Saito Y, Narumiya S (September 1996). "Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase". The Journal of Biological Chemistry. 271 (38): 23022–8. doi:10.1074/jbc.271.38.23022. PMID 8798490.
Croft DR, Sahai E, Mavria G, Li S, Tsai J, Lee WM, Marshall CJ, Olson MF (December 2004). "Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis". Cancer Research. 64 (24): 8994–9001. doi:10.1158/0008-5472.CAN-04-2052. PMID 15604264. S2CID 8380551.
Tönges L, Frank T, Tatenhorst L, Saal KA, Koch JC, Szego ÉM, Bähr M, Weishaupt JH, Lingor P (November 2012). "Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease". Brain. 135 (Pt 11): 3355–70. doi:10.1093/brain/aws254. PMC 3501973. PMID 23087045.
Dahal BK, Kosanovic D, Pamarthi PK, Sydykov A, Lai YJ, Kast R, Schirok H, Stasch JP, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Schermuly RT (October 2010). "Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension". The European Respiratory Journal. 36 (4): 808–18. doi:10.1183/09031936.00140309. PMID 20530035.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Rath N, Olson MF (October 2012). "Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy". EMBO Reports. 13 (10): 900–8. doi:10.1038/embor.2012.127. PMC 3463970. PMID 22964758.
"ROCK1 Rho-associated, coiled-coil containing protein kinase 1 [ Homo sapiens (human) ]".
Hahmann C, Schroeter T (January 2010). "Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity". Cellular and Molecular Life Sciences. 67 (2): 171–7. doi:10.1007/s00018-009-0189-x. PMC 11115778. PMID 19907920. S2CID 6445354.
"Rho Kinase in Vascular Smooth Muscle". Chapter 7Rho Kinase in Vascular Smooth Muscle. Morgan & Claypool Life Sciences. 2010.
Truebestein L, Elsner DJ, Fuchs E, Leonard TA (2015-12-01). "A molecular ruler regulates cytoskeletal remodelling by the Rho kinases". Nature Communications. 6: 10029. Bibcode:2015NatCo...610029T. doi:10.1038/ncomms10029. PMC 4686654. PMID 26620183.
"Entrez Gene: ROCK1 Rho-associated, coiled-coil containing protein kinase 1".
Da Silva JS, Medina M, Zuliani C, Di Nardo A, Witke W, Dotti CG (September 2003). "RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability". The Journal of Cell Biology. 162 (7): 1267–79. doi:10.1083/jcb.200304021. PMC 2173969. PMID 14517206.
Riento K, Guasch RM, Garg R, Jin B, Ridley AJ (June 2003). "RhoE binds to ROCK I and inhibits downstream signaling". Molecular and Cellular Biology. 23 (12): 4219–29. doi:10.1128/mcb.23.12.4219-4229.2003. PMC 156133. PMID 12773565.
Leung T, Chen XQ, Manser E, Lim L (October 1996). "The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton". Molecular and Cellular Biology. 16 (10): 5313–27. doi:10.1128/mcb.16.10.5313. PMC 231530. PMID 8816443.
Tönges L, Frank T, Tatenhorst L, Saal KA, Koch JC, Szego ÉM, Bähr M, Weishaupt JH, Lingor P (November 2012). "Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease". Brain. 135 (Pt 11): 3355–70. doi:10.1093/brain/aws254. PMC 3501973. PMID 23087045.

physiology.org

ajpheart.physiology.org

Kroll, Jens; Epting, Daniel; Kern, Katrin; Dietz, Christian T.; Feng, Yuxi; Hammes, Hans-Peter; Wieland, Thomas; Augustin, Hellmut G. (2009). "Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis". American Journal of Physiology. Heart and Circulatory Physiology. 296 (3): H893–H899. doi:10.1152/ajpheart.01038.2008. PMID 19181962.

semanticscholar.org

api.semanticscholar.org

Hahmann C, Schroeter T (January 2010). "Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity". Cellular and Molecular Life Sciences. 67 (2): 171–7. doi:10.1007/s00018-009-0189-x. PMC 11115778. PMID 19907920. S2CID 6445354.
Riento K, Ridley AJ (June 2003). "Rocks: multifunctional kinases in cell behaviour". Nature Reviews Molecular Cell Biology. 4 (6): 446–56. doi:10.1038/nrm1128. PMID 12778124. S2CID 40665081.
Nakagawa O, Fujisawa K, Ishizaki T, Saito Y, Nakao K, Narumiya S (August 1996). "ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice". FEBS Letters. 392 (2): 189–93. doi:10.1016/0014-5793(96)00811-3. PMID 8772201. S2CID 6684411.
Croft DR, Sahai E, Mavria G, Li S, Tsai J, Lee WM, Marshall CJ, Olson MF (December 2004). "Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis". Cancer Research. 64 (24): 8994–9001. doi:10.1158/0008-5472.CAN-04-2052. PMID 15604264. S2CID 8380551.

uniprot.org

"Q13464 (ROCK1_HUMAN)".