TRPC6 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "TRPC6" in English language version.

refsWebsite

Global rank English rank

40nih.gov

4^th place

23doi.org

2^nd place

3harvard.edu

18^th place

17^th place

2ensembl.org

1,626^th place

1,007^th place

2semanticscholar.org

11^th place

8^th place

1creativecommons.org

1,010^th place

612^th place

creativecommons.org

Zernov N, Popugaeva E (October 2023). "Role of Neuronal TRPC6 Channels in Synapse Development, Memory Formation and Animal Behavior". International Journal of Molecular Sciences. 24 (20): 15415. doi:10.3390/ijms242015415. PMC 10607207. PMID 37895105. This article incorporates text available under the CC BY 4.0 license.

doi.org

Tang Q, Guo W, Zheng L, Wu JX, Liu M, Zhou X, et al. (July 2018). "Structure of the receptor-activated human TRPC6 and TRPC3 ion channels". Cell Research. 28 (7): 746–755. doi:10.1038/s41422-018-0038-2. PMC 6028632. PMID 29700422.
Dietrich A, Gudermann T (2014). "TRPC6: Physiological Function and Pathophysiological Relevance". Mammalian Transient Receptor Potential (TRP) Cation Channels. Handbook of Experimental Pharmacology. Vol. 222. pp. 157–88. doi:10.1007/978-3-642-54215-2_7. ISBN 978-3-642-54214-5. PMID 24756706.
Oda S, Nishiyama K, Furumoto Y, Yamaguchi Y, Nishimura A, Tang X, et al. (October 2022). "Myocardial TRPC6-mediated Zn²⁺ influx induces beneficial positive inotropy through β-adrenoceptors". Nature Communications. 13 (1): 6374. Bibcode:2022NatCo..13.6374O. doi:10.1038/s41467-022-34194-9. PMC 9606288. PMID 36289215.
Brayden JE, Earley S, Nelson MT, Reading S (September 2008). "Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow". Clinical and Experimental Pharmacology & Physiology. 35 (9): 1116–1120. doi:10.1111/j.1440-1681.2007.04855.x. PMC 4193799. PMID 18215190.
Abdinghoff J, Servello D, Jacobs T, Beckmann A, Tschernig T (May 2022). "Evaluation of the presence of TRPC6 channels in human vessels: A pilot study using immunohistochemistry". Biomedical Reports. 16 (5): 42. doi:10.3892/br.2022.1525. PMC 8972230. PMID 35371476.
Reiser J, Polu KR, Möller CC, Kenlan P, Altintas MM, Wei C, et al. (July 2005). "TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function". Nature Genetics. 37 (7): 739–744. doi:10.1038/ng1592. PMC 1360984. PMID 15924139.
Tomilin V, Mamenko M, Zaika O, Pochynyuk O (May 2016). "Role of renal TRP channels in physiology and pathology". Seminars in Immunopathology. 38 (3): 371–383. doi:10.1007/s00281-015-0527-z. PMC 4798925. PMID 26385481.
Kanthakumar P, Adebiyi A (2021). "Renal vascular TRP channels". Current Research in Physiology. 4: 17–23. doi:10.1016/j.crphys.2021.02.001. PMC 8225244. PMID 34179830.
Morton MJ, Hutchinson K, Mathieson PW, Witherden IR, Saleem MA, Hunter M (December 2004). "Human podocytes possess a stretch-sensitive, Ca2+-activated K+ channel: potential implications for the control of glomerular filtration". Journal of the American Society of Nephrology. 15 (12): 2981–2987. doi:10.1097/01.ASN.0000145046.24268.0D. PMID 15579500.
Dryer SE, Reiser J (October 2010). "TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology". American Journal of Physiology. Renal Physiology. 299 (4): F689 – F701. doi:10.1152/ajprenal.00298.2010. PMC 2957253. PMID 20685822.
Welsh GI, Saleem MA (October 2011). "The podocyte cytoskeleton--key to a functioning glomerulus in health and disease". Nature Reviews. Nephrology. 8 (1): 14–21. doi:10.1038/nrneph.2011.151. PMID 22025085. In these lipid microdomains, podocin clusters and regulates the ion channel TRPC6 and it has been suggested that this regulation gives the slit diaphragm the ability to act as a mechanosensor that enables the podocyte to remodel its cytoskeleton and contract its foot processes in response to mechanical stimuli.
Carlström M, Wilcox CS, Arendshorst WJ (April 2015). "Renal autoregulation in health and disease". Physiological Reviews. 95 (2): 405–511. doi:10.1152/physrev.00042.2012. PMC 4551215. PMID 25834230.
Tian D, Jacobo SM, Billing D, Rozkalne A, Gage SD, Anagnostou T, et al. (October 2010). "Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels". Science Signaling. 3 (145): ra77. doi:10.1126/scisignal.2001200. PMC 3071756. PMID 20978238.
Hu S, Han R, Chen L, Qin W, Xu X, Shi J, et al. (March 2021). "Upregulated LRRC55 promotes BK channel activation and aggravates cell injury in podocytes". The Journal of Experimental Medicine. 218 (3). doi:10.1084/jem.20192373. PMC 7756252. PMID 33346797.
Zernov N, Popugaeva E (October 2023). "Role of Neuronal TRPC6 Channels in Synapse Development, Memory Formation and Animal Behavior". International Journal of Molecular Sciences. 24 (20): 15415. doi:10.3390/ijms242015415. PMC 10607207. PMID 37895105. This article incorporates text available under the CC BY 4.0 license.
Saqib U, Munjuluri S, Sarkar S, Biswas S, Mukherjee O, Satsangi H, et al. (August 2023). "Transient Receptor Potential Canonical 6 (TRPC6) Channel in the Pathogenesis of Diseases: A Jack of Many Trades". Inflammation. 46 (4): 1144–1160. doi:10.1007/s10753-023-01808-3. PMC 10112830. PMID 37072606.
Hisatsune C, Kuroda Y, Nakamura K, Inoue T, Nakamura T, Michikawa T, et al. (April 2004). "Regulation of TRPC6 channel activity by tyrosine phosphorylation". The Journal of Biological Chemistry. 279 (18): 18887–18894. doi:10.1074/jbc.M311274200. PMID 14761972.
Chu X, Tong Q, Cheung JY, Wozney J, Conrad K, Mazack V, et al. (March 2004). "Interaction of TRPC2 and TRPC6 in erythropoietin modulation of calcium influx". The Journal of Biological Chemistry. 279 (11): 10514–10522. doi:10.1074/jbc.M308478200. PMID 14699131.
Hofmann T, Schaefer M, Schultz G, Gudermann T (May 2002). "Subunit composition of mammalian transient receptor potential channels in living cells". Proceedings of the National Academy of Sciences of the United States of America. 99 (11): 7461–7466. Bibcode:2002PNAS...99.7461H. doi:10.1073/pnas.102596199. PMC 124253. PMID 12032305.
Müller WE, Singer A, Wonnemann M (July 2001). "Hyperforin--antidepressant activity by a novel mechanism of action". Pharmacopsychiatry. 34 (Suppl 1): S98-102. doi:10.1055/s-2001-15512. PMID 11518085. S2CID 21872392.
Chatterjee SS, Bhattacharya SK, Wonnemann M, Singer A, Müller WE (1998). "Hyperforin as a possible antidepressant component of hypericum extracts". Life Sciences. 63 (6): 499–510. doi:10.1016/S0024-3205(98)00299-9. PMID 9718074.
Leuner K, Kazanski V, Müller M, Essin K, Henke B, Gollasch M, et al. (December 2007). "Hyperforin--a key constituent of St. John's wort specifically activates TRPC6 channels". FASEB Journal. 21 (14): 4101–4111. doi:10.1096/fj.07-8110com. PMID 17666455. S2CID 14097884.
Sell TS, Belkacemi T, Flockerzi V, Beck A (December 2014). "Protonophore properties of hyperforin are essential for its pharmacological activity". Scientific Reports. 4: 7500. Bibcode:2014NatSR...4E7500S. doi:10.1038/srep07500. PMC 4266863. PMID 25511254.

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000137672 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000031997 – Ensembl, May 2017

harvard.edu

ui.adsabs.harvard.edu

Oda S, Nishiyama K, Furumoto Y, Yamaguchi Y, Nishimura A, Tang X, et al. (October 2022). "Myocardial TRPC6-mediated Zn²⁺ influx induces beneficial positive inotropy through β-adrenoceptors". Nature Communications. 13 (1): 6374. Bibcode:2022NatCo..13.6374O. doi:10.1038/s41467-022-34194-9. PMC 9606288. PMID 36289215.
Hofmann T, Schaefer M, Schultz G, Gudermann T (May 2002). "Subunit composition of mammalian transient receptor potential channels in living cells". Proceedings of the National Academy of Sciences of the United States of America. 99 (11): 7461–7466. Bibcode:2002PNAS...99.7461H. doi:10.1073/pnas.102596199. PMC 124253. PMID 12032305.
Sell TS, Belkacemi T, Flockerzi V, Beck A (December 2014). "Protonophore properties of hyperforin are essential for its pharmacological activity". Scientific Reports. 4: 7500. Bibcode:2014NatSR...4E7500S. doi:10.1038/srep07500. PMC 4266863. PMID 25511254.

nih.gov

pubmed.ncbi.nlm.nih.gov

Tang Q, Guo W, Zheng L, Wu JX, Liu M, Zhou X, et al. (July 2018). "Structure of the receptor-activated human TRPC6 and TRPC3 ion channels". Cell Research. 28 (7): 746–755. doi:10.1038/s41422-018-0038-2. PMC 6028632. PMID 29700422.
Dietrich A, Gudermann T (2014). "TRPC6: Physiological Function and Pathophysiological Relevance". Mammalian Transient Receptor Potential (TRP) Cation Channels. Handbook of Experimental Pharmacology. Vol. 222. pp. 157–88. doi:10.1007/978-3-642-54215-2_7. ISBN 978-3-642-54214-5. PMID 24756706.
Oda S, Nishiyama K, Furumoto Y, Yamaguchi Y, Nishimura A, Tang X, et al. (October 2022). "Myocardial TRPC6-mediated Zn²⁺ influx induces beneficial positive inotropy through β-adrenoceptors". Nature Communications. 13 (1): 6374. Bibcode:2022NatCo..13.6374O. doi:10.1038/s41467-022-34194-9. PMC 9606288. PMID 36289215.
Brayden JE, Earley S, Nelson MT, Reading S (September 2008). "Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow". Clinical and Experimental Pharmacology & Physiology. 35 (9): 1116–1120. doi:10.1111/j.1440-1681.2007.04855.x. PMC 4193799. PMID 18215190.
Abdinghoff J, Servello D, Jacobs T, Beckmann A, Tschernig T (May 2022). "Evaluation of the presence of TRPC6 channels in human vessels: A pilot study using immunohistochemistry". Biomedical Reports. 16 (5): 42. doi:10.3892/br.2022.1525. PMC 8972230. PMID 35371476.
Reiser J, Polu KR, Möller CC, Kenlan P, Altintas MM, Wei C, et al. (July 2005). "TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function". Nature Genetics. 37 (7): 739–744. doi:10.1038/ng1592. PMC 1360984. PMID 15924139.
Tomilin V, Mamenko M, Zaika O, Pochynyuk O (May 2016). "Role of renal TRP channels in physiology and pathology". Seminars in Immunopathology. 38 (3): 371–383. doi:10.1007/s00281-015-0527-z. PMC 4798925. PMID 26385481.
Kanthakumar P, Adebiyi A (2021). "Renal vascular TRP channels". Current Research in Physiology. 4: 17–23. doi:10.1016/j.crphys.2021.02.001. PMC 8225244. PMID 34179830.
Morton MJ, Hutchinson K, Mathieson PW, Witherden IR, Saleem MA, Hunter M (December 2004). "Human podocytes possess a stretch-sensitive, Ca2+-activated K+ channel: potential implications for the control of glomerular filtration". Journal of the American Society of Nephrology. 15 (12): 2981–2987. doi:10.1097/01.ASN.0000145046.24268.0D. PMID 15579500.
Dryer SE, Reiser J (October 2010). "TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology". American Journal of Physiology. Renal Physiology. 299 (4): F689 – F701. doi:10.1152/ajprenal.00298.2010. PMC 2957253. PMID 20685822.
Welsh GI, Saleem MA (October 2011). "The podocyte cytoskeleton--key to a functioning glomerulus in health and disease". Nature Reviews. Nephrology. 8 (1): 14–21. doi:10.1038/nrneph.2011.151. PMID 22025085. In these lipid microdomains, podocin clusters and regulates the ion channel TRPC6 and it has been suggested that this regulation gives the slit diaphragm the ability to act as a mechanosensor that enables the podocyte to remodel its cytoskeleton and contract its foot processes in response to mechanical stimuli.
Carlström M, Wilcox CS, Arendshorst WJ (April 2015). "Renal autoregulation in health and disease". Physiological Reviews. 95 (2): 405–511. doi:10.1152/physrev.00042.2012. PMC 4551215. PMID 25834230.
Tian D, Jacobo SM, Billing D, Rozkalne A, Gage SD, Anagnostou T, et al. (October 2010). "Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels". Science Signaling. 3 (145): ra77. doi:10.1126/scisignal.2001200. PMC 3071756. PMID 20978238.
Hu S, Han R, Chen L, Qin W, Xu X, Shi J, et al. (March 2021). "Upregulated LRRC55 promotes BK channel activation and aggravates cell injury in podocytes". The Journal of Experimental Medicine. 218 (3). doi:10.1084/jem.20192373. PMC 7756252. PMID 33346797.
Zernov N, Popugaeva E (October 2023). "Role of Neuronal TRPC6 Channels in Synapse Development, Memory Formation and Animal Behavior". International Journal of Molecular Sciences. 24 (20): 15415. doi:10.3390/ijms242015415. PMC 10607207. PMID 37895105. This article incorporates text available under the CC BY 4.0 license.
Saqib U, Munjuluri S, Sarkar S, Biswas S, Mukherjee O, Satsangi H, et al. (August 2023). "Transient Receptor Potential Canonical 6 (TRPC6) Channel in the Pathogenesis of Diseases: A Jack of Many Trades". Inflammation. 46 (4): 1144–1160. doi:10.1007/s10753-023-01808-3. PMC 10112830. PMID 37072606.
Hisatsune C, Kuroda Y, Nakamura K, Inoue T, Nakamura T, Michikawa T, et al. (April 2004). "Regulation of TRPC6 channel activity by tyrosine phosphorylation". The Journal of Biological Chemistry. 279 (18): 18887–18894. doi:10.1074/jbc.M311274200. PMID 14761972.
Chu X, Tong Q, Cheung JY, Wozney J, Conrad K, Mazack V, et al. (March 2004). "Interaction of TRPC2 and TRPC6 in erythropoietin modulation of calcium influx". The Journal of Biological Chemistry. 279 (11): 10514–10522. doi:10.1074/jbc.M308478200. PMID 14699131.
Hofmann T, Schaefer M, Schultz G, Gudermann T (May 2002). "Subunit composition of mammalian transient receptor potential channels in living cells". Proceedings of the National Academy of Sciences of the United States of America. 99 (11): 7461–7466. Bibcode:2002PNAS...99.7461H. doi:10.1073/pnas.102596199. PMC 124253. PMID 12032305.
Müller WE, Singer A, Wonnemann M (July 2001). "Hyperforin--antidepressant activity by a novel mechanism of action". Pharmacopsychiatry. 34 (Suppl 1): S98-102. doi:10.1055/s-2001-15512. PMID 11518085. S2CID 21872392.
Chatterjee SS, Bhattacharya SK, Wonnemann M, Singer A, Müller WE (1998). "Hyperforin as a possible antidepressant component of hypericum extracts". Life Sciences. 63 (6): 499–510. doi:10.1016/S0024-3205(98)00299-9. PMID 9718074.
Leuner K, Kazanski V, Müller M, Essin K, Henke B, Gollasch M, et al. (December 2007). "Hyperforin--a key constituent of St. John's wort specifically activates TRPC6 channels". FASEB Journal. 21 (14): 4101–4111. doi:10.1096/fj.07-8110com. PMID 17666455. S2CID 14097884.
Sell TS, Belkacemi T, Flockerzi V, Beck A (December 2014). "Protonophore properties of hyperforin are essential for its pharmacological activity". Scientific Reports. 4: 7500. Bibcode:2014NatSR...4E7500S. doi:10.1038/srep07500. PMC 4266863. PMID 25511254.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Tang Q, Guo W, Zheng L, Wu JX, Liu M, Zhou X, et al. (July 2018). "Structure of the receptor-activated human TRPC6 and TRPC3 ion channels". Cell Research. 28 (7): 746–755. doi:10.1038/s41422-018-0038-2. PMC 6028632. PMID 29700422.
Oda S, Nishiyama K, Furumoto Y, Yamaguchi Y, Nishimura A, Tang X, et al. (October 2022). "Myocardial TRPC6-mediated Zn²⁺ influx induces beneficial positive inotropy through β-adrenoceptors". Nature Communications. 13 (1): 6374. Bibcode:2022NatCo..13.6374O. doi:10.1038/s41467-022-34194-9. PMC 9606288. PMID 36289215.
Brayden JE, Earley S, Nelson MT, Reading S (September 2008). "Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow". Clinical and Experimental Pharmacology & Physiology. 35 (9): 1116–1120. doi:10.1111/j.1440-1681.2007.04855.x. PMC 4193799. PMID 18215190.
Abdinghoff J, Servello D, Jacobs T, Beckmann A, Tschernig T (May 2022). "Evaluation of the presence of TRPC6 channels in human vessels: A pilot study using immunohistochemistry". Biomedical Reports. 16 (5): 42. doi:10.3892/br.2022.1525. PMC 8972230. PMID 35371476.
Reiser J, Polu KR, Möller CC, Kenlan P, Altintas MM, Wei C, et al. (July 2005). "TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function". Nature Genetics. 37 (7): 739–744. doi:10.1038/ng1592. PMC 1360984. PMID 15924139.
Tomilin V, Mamenko M, Zaika O, Pochynyuk O (May 2016). "Role of renal TRP channels in physiology and pathology". Seminars in Immunopathology. 38 (3): 371–383. doi:10.1007/s00281-015-0527-z. PMC 4798925. PMID 26385481.
Kanthakumar P, Adebiyi A (2021). "Renal vascular TRP channels". Current Research in Physiology. 4: 17–23. doi:10.1016/j.crphys.2021.02.001. PMC 8225244. PMID 34179830.
Dryer SE, Reiser J (October 2010). "TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology". American Journal of Physiology. Renal Physiology. 299 (4): F689 – F701. doi:10.1152/ajprenal.00298.2010. PMC 2957253. PMID 20685822.
Carlström M, Wilcox CS, Arendshorst WJ (April 2015). "Renal autoregulation in health and disease". Physiological Reviews. 95 (2): 405–511. doi:10.1152/physrev.00042.2012. PMC 4551215. PMID 25834230.
Tian D, Jacobo SM, Billing D, Rozkalne A, Gage SD, Anagnostou T, et al. (October 2010). "Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels". Science Signaling. 3 (145): ra77. doi:10.1126/scisignal.2001200. PMC 3071756. PMID 20978238.
Hu S, Han R, Chen L, Qin W, Xu X, Shi J, et al. (March 2021). "Upregulated LRRC55 promotes BK channel activation and aggravates cell injury in podocytes". The Journal of Experimental Medicine. 218 (3). doi:10.1084/jem.20192373. PMC 7756252. PMID 33346797.
Zernov N, Popugaeva E (October 2023). "Role of Neuronal TRPC6 Channels in Synapse Development, Memory Formation and Animal Behavior". International Journal of Molecular Sciences. 24 (20): 15415. doi:10.3390/ijms242015415. PMC 10607207. PMID 37895105. This article incorporates text available under the CC BY 4.0 license.
Saqib U, Munjuluri S, Sarkar S, Biswas S, Mukherjee O, Satsangi H, et al. (August 2023). "Transient Receptor Potential Canonical 6 (TRPC6) Channel in the Pathogenesis of Diseases: A Jack of Many Trades". Inflammation. 46 (4): 1144–1160. doi:10.1007/s10753-023-01808-3. PMC 10112830. PMID 37072606.
Hofmann T, Schaefer M, Schultz G, Gudermann T (May 2002). "Subunit composition of mammalian transient receptor potential channels in living cells". Proceedings of the National Academy of Sciences of the United States of America. 99 (11): 7461–7466. Bibcode:2002PNAS...99.7461H. doi:10.1073/pnas.102596199. PMC 124253. PMID 12032305.
Sell TS, Belkacemi T, Flockerzi V, Beck A (December 2014). "Protonophore properties of hyperforin are essential for its pharmacological activity". Scientific Reports. 4: 7500. Bibcode:2014NatSR...4E7500S. doi:10.1038/srep07500. PMC 4266863. PMID 25511254.

semanticscholar.org

api.semanticscholar.org

Müller WE, Singer A, Wonnemann M (July 2001). "Hyperforin--antidepressant activity by a novel mechanism of action". Pharmacopsychiatry. 34 (Suppl 1): S98-102. doi:10.1055/s-2001-15512. PMID 11518085. S2CID 21872392.
Leuner K, Kazanski V, Müller M, Essin K, Henke B, Gollasch M, et al. (December 2007). "Hyperforin--a key constituent of St. John's wort specifically activates TRPC6 channels". FASEB Journal. 21 (14): 4101–4111. doi:10.1096/fj.07-8110com. PMID 17666455. S2CID 14097884.