PDB2B8T; Kosinska U, Carnrot C, Eriksson S, Wang L, Eklund H. Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme. FEBS J. December 2005, 272 (24): 6365–72. PMID 16336273. doi:10.1111/j.1742-4658.2005.05030.x.
Halliburton IW, Morse LS, Roizman B, Quinn KE. Mapping of the thymidine kinase genes of type 1 and type 2 herpes simplex viruses using intertypic recombinants. J. Gen. Virol. August 1980, 49 (2): 235–53. PMID 6255066. doi:10.1099/0022-1317-49-2-235.
Kit S, Kit M, Qavi H, Trkula D, Otsuka H. Nucleotide sequence of the herpes simplex virus type 2 (HSV-2) thymidine kinase gene and predicted amino acid sequence of thymidine kinase polypeptide and its comparison with the HSV-1 thymidine kinase gene. Biochim. Biophys. Acta. November 1983, 741 (2): 158–70. PMID 6317035. doi:10.1016/0167-4781(83)90056-8.
Sawyer MH, Ostrove JM, Felser JM, Straus SE. Mapping of the varicella zoster virus deoxypyrimidine kinase gene and preliminary identification of its transcript. Virology. February 1986, 149 (1): 1–9. PMID 3004022. doi:10.1016/0042-6822(86)90081-4.
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Gross MK, Kainz MS, Merrill GF. The chicken thymidine kinase gene is transcriptionally repressed during terminal differentiation: the associated decline in TK mRNA cannot account fully for the disappearance of TK enzyme activity. Dev. Biol. August 1987, 122 (2): 439–51. PMID 3596017. doi:10.1016/0012-1606(87)90308-3.
Sutterluety H, Bartl S, Karlseder J, Wintersberger E, Seiser C. Carboxy-terminal residues of mouse thymidine kinase are essential for rapid degradation in quiescent cells. J. Mol. Biol. June 1996, 259 (3): 383–92. PMID 8676376. doi:10.1006/jmbi.1996.0327.
Chao KS. Functional imaging for early prediction of response to chemoradiotherapy: 3'-deoxy-3'-18F-fluorothymidine positron emission tomography--a clinical application model of esophageal cancer. Semin. Oncol. December 2006, 33 (6 Suppl 11): S59–63. PMID 17178290. doi:10.1053/j.seminoncol.2006.10.011.
Salskov A, Tammisetti VS, Grierson J, Vesselle H. FLT: measuring tumor cell proliferation in vivo with positron emission tomography and 3'-deoxy-3'-[18F]fluorothymidine. Semin Nucl Med. November 2007, 37 (6): 429–39. PMID 17920350. doi:10.1053/j.semnuclmed.2007.08.001.
de Langen AJ; Klabbers B; Lubberink M; et al. Reproducibility of quantitative (18)F-3'-deoxy-3'-fluorothymidine measurements using positron emission tomography. Eur. J. Nucl. Med. Mol. Imaging. October 2008, 36 (3): 389–95. PMID 18931838. doi:10.1007/s00259-008-0960-5.
Shields AF; Lawhorn-Crews JM; Briston DA; et al. Analysis and reproducibility of 3'-Deoxy-3'-[18F]fluorothymidine positron emission tomography imaging in patients with non-small cell lung cancer. Clin. Cancer Res. July 2008, 14 (14): 4463–8. PMID 18628460. doi:10.1158/1078-0432.CCR-07-5243.
Köhler G, Howe SC, Milstein C. Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines. Eur. J. Immunol. April 1976, 6 (4): 292–5. PMID 825374. doi:10.1002/eji.1830060411.
Köhler G, Milstein C. Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion. Eur. J. Immunol. July 1976, 6 (7): 511–9. PMID 825377. doi:10.1002/eji.1830060713.
Köhler G, Pearson T, Milstein C. Fusion of T and B cells. Somatic Cell Genet. May 1977, 3 (3): 303–12. PMID 305123. doi:10.1007/BF01538748.
Karlström AR, Neumüller M, Gronowitz JS, Källander CF. Molecular forms in human serum of enzymes synthesizing DNA precursors and DNA. Mol. Cell. Biochem. January 1990, 92 (1): 23–35. PMID 2155379. doi:10.1007/BF00220716.
Hagberg H, Glimelius B, Gronowitz JS, Killander A, Källander CFR, Schröder T. Biochemical markers in non-Hodgkin's lymphoma stages III and IV and prognosis: a multivariate analysis. Scand J Haematol. July 1984, 33 (1): 59–67. PMID 6379852. doi:10.1111/j.1600-0609.1984.tb02211.x.
Hallek M, Wanders L, Strohmeyer S, Emmerich B. Thymidine kinase: a tumor marker with prognostic value for non-Hodgkin's lymphoma and a broad range of potential clinical applications. Ann. Hematol. July 1992, 65 (1): 1–5. PMID 1643153. doi:10.1007/BF01715117.
Suki S, Swan F, Tucker S; et al. Risk classification for large cell lymphoma using lactate dehydrogenase, beta-2 microglobulin, and thymidine kinase. Leuk. Lymphoma. June 1995, 18 (1–2): 87–92. PMID 8580834. doi:10.3109/10428199509064927. 引文格式1维护:显式使用等标签 (link)
Hallek M, Wanders L, Ostwald M; et al. Serum beta(2)-microglobulin and serum thymidine kinase are independent predictors of progression-free survival in chronic lymphocytic leukemia and immunocytoma. Leuk. Lymphoma. August 1996, 22 (5–6): 439–47. PMID 8882957. doi:10.3109/10428199609054782. 引文格式1维护:显式使用等标签 (link)
Källander CFR, Simonsson B, Gronowitz JS, Nilsson K. Serum deoxythymidine kinase correlates with peripheral lymphocyte thymidine uptake in chronic lymphocytic leukemia. Eur. J. Haematol. April 1987, 38 (4): 331–7. PMID 3609253. doi:10.1111/j.1600-0609.1987.tb00007.x.
Lin TS, Neenan JP, Cheng YC, Prusoff WH. Synthesis and antiviral activity of 5- and 5'-substituted thymidine analogs. J. Med. Chem. April 1976, 19 (4): 495–8. PMID 177781. doi:10.1021/jm00226a009.
Shiau GT, Schinazi RF, Chen MS, Prusoff WH. Synthesis and biological activities of 5-(hydroxymethyl, azidomethyl, or aminomethyl)-2'-deoxyuridine and related 5'-substituted analogues. J. Med. Chem. February 1980, 23 (2): 127–33. PMID 6244411. doi:10.1021/jm00176a005.
Prusoff WH. Synthesis and biological activities of iododeoxyuridine, an analog of thymidine. Biochim. Biophys. Acta. March 1959, 32 (1): 295–6. PMID 13628760. doi:10.1016/0006-3002(59)90597-9.
Morgenroth A, Deisenhofer S, Glatting G; et al. Preferential Tumor Targeting and Selective Tumor Cell Cytotoxicity of 5-[131/125I]Iodo-4'-Thio-2'-Deoxyuridine. Clin. Cancer Res. November 2008, 14 (22): 7311–9. PMID 19010846. doi:10.1158/1078-0432.CCR-08-0907. 引文格式1维护:显式使用等标签 (link)
Byun Y, Yan J, Al-Madhoun AS; et al. Synthesis and biological evaluation of neutral and zwitterionic 3-carboranyl thymidine analogues for boron neutron capture therapy. J. Med. Chem. February 2005, 48 (4): 1188–98. PMID 15715485. doi:10.1021/jm0491896. 引文格式1维护:显式使用等标签 (link)
Barth RF, Yang W, Al-Madhoun AS; et al. Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors. Cancer Res. September 2004, 64 (17): 6287–95. PMID 15342417. doi:10.1158/0008-5472.CAN-04-0437. 引文格式1维护:显式使用等标签 (link)
Al-Madhoun AS, Johnsamuel J, Barth RF, Tjarks W, Eriksson S. Evaluation of human thymidine kinase 1 substrates as new candidates for boron neutron capture therapy. Cancer Res. September 2004, 64 (17): 6280–6. PMID 15342416. doi:10.1158/0008-5472.CAN-04-0197.
Johnsamuel J, Lakhi N, Al-Madhoun AS; et al. Synthesis of ethyleneoxide modified 3-carboranyl thymidine analogues and evaluation of their biochemical, physicochemical, and structural properties. Bioorg. Med. Chem. September 2004, 12 (18): 4769–81. PMID 15336255. doi:10.1016/j.bmc.2004.07.032. 引文格式1维护:显式使用等标签 (link)
Byun Y, Yan J, Al-Madhoun AS; et al. The synthesis and biochemical evaluation of thymidine analogues substituted with nido carborane at the N-3 position. Appl Radiat Isot. November 2004, 61 (5): 1125–30. PMID 15308203. doi:10.1016/j.apradiso.2004.05.023. 引文格式1维护:显式使用等标签 (link)
Gronowitz JS, Källander FR, Diderholm H, Hagberg H, Pettersson U. Application of an in vitro assay for serum thymidine kinase: results on viral disease and malignancies in humans. Int. J. Cancer. January 1984, 33 (1): 5–12. PMID 6693195. doi:10.1002/ijc.2910330103.
Romain S, Spyratos F, Guirou O, Deytieux S, Chinot O, Martin PM. Technical evaluation of thymidine kinase assay in cytosols from breast cancers. EORTC Receptor Study Group Report. Eur. J. Cancer. 1994, 30A (14): 2163–5. PMID 7857717. doi:10.1016/0959-8049(94)00376-G.
Schollenberger S, Taureck D, Wilmanns W. [Enzymes of thymidine and thymidylate metabolism in normal and pathological blood and bone marrow cells] [Enzymes of thymidine and thymidylate metabolism in normal and pathological blood and bone marrow cells]. Blut. November 1972, 25 (5): 318–34. PMID 4508724. doi:10.1007/BF01631814(德语).
Nakao K, Fujioka S. Thymidine kinase activity in the human bone marrow from various blood diseases. Life Sci. April 1968, 7 (8): 395–9. PMID 5649653. doi:10.1016/0024-3205(68)90039-8.
Romain S, Chinot O, Guirou O, Soullière M, Martin PM. Biological heterogeneity of ER-positive breast cancers in the post-menopausal population. Int. J. Cancer. October 1994, 59 (1): 17–9. PMID 7927897. doi:10.1002/ijc.2910590105.
Sakamoto S, Murakami S, Sugawara M, Mishima Y, Okamoto R. Increased activities of thymidylate synthetase and thymidine kinase in human thyroid tumors. Thyroid. 1991, 1 (4): 347–51. PMID 1841732. doi:10.1089/thy.1991.1.347.
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PDB2B8T; Kosinska U, Carnrot C, Eriksson S, Wang L, Eklund H. Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme. FEBS J. December 2005, 272 (24): 6365–72. PMID 16336273. doi:10.1111/j.1742-4658.2005.05030.x.
Halliburton IW, Morse LS, Roizman B, Quinn KE. Mapping of the thymidine kinase genes of type 1 and type 2 herpes simplex viruses using intertypic recombinants. J. Gen. Virol. August 1980, 49 (2): 235–53. PMID 6255066. doi:10.1099/0022-1317-49-2-235.
Kit S, Kit M, Qavi H, Trkula D, Otsuka H. Nucleotide sequence of the herpes simplex virus type 2 (HSV-2) thymidine kinase gene and predicted amino acid sequence of thymidine kinase polypeptide and its comparison with the HSV-1 thymidine kinase gene. Biochim. Biophys. Acta. November 1983, 741 (2): 158–70. PMID 6317035. doi:10.1016/0167-4781(83)90056-8.
Sawyer MH, Ostrove JM, Felser JM, Straus SE. Mapping of the varicella zoster virus deoxypyrimidine kinase gene and preliminary identification of its transcript. Virology. February 1986, 149 (1): 1–9. PMID 3004022. doi:10.1016/0042-6822(86)90081-4.
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Gross MK, Kainz MS, Merrill GF. The chicken thymidine kinase gene is transcriptionally repressed during terminal differentiation: the associated decline in TK mRNA cannot account fully for the disappearance of TK enzyme activity. Dev. Biol. August 1987, 122 (2): 439–51. PMID 3596017. doi:10.1016/0012-1606(87)90308-3.
Sutterluety H, Bartl S, Karlseder J, Wintersberger E, Seiser C. Carboxy-terminal residues of mouse thymidine kinase are essential for rapid degradation in quiescent cells. J. Mol. Biol. June 1996, 259 (3): 383–92. PMID 8676376. doi:10.1006/jmbi.1996.0327.
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Salskov A, Tammisetti VS, Grierson J, Vesselle H. FLT: measuring tumor cell proliferation in vivo with positron emission tomography and 3'-deoxy-3'-[18F]fluorothymidine. Semin Nucl Med. November 2007, 37 (6): 429–39. PMID 17920350. doi:10.1053/j.semnuclmed.2007.08.001.
de Langen AJ; Klabbers B; Lubberink M; et al. Reproducibility of quantitative (18)F-3'-deoxy-3'-fluorothymidine measurements using positron emission tomography. Eur. J. Nucl. Med. Mol. Imaging. October 2008, 36 (3): 389–95. PMID 18931838. doi:10.1007/s00259-008-0960-5.
Shields AF; Lawhorn-Crews JM; Briston DA; et al. Analysis and reproducibility of 3'-Deoxy-3'-[18F]fluorothymidine positron emission tomography imaging in patients with non-small cell lung cancer. Clin. Cancer Res. July 2008, 14 (14): 4463–8. PMID 18628460. doi:10.1158/1078-0432.CCR-07-5243.
Köhler G, Howe SC, Milstein C. Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines. Eur. J. Immunol. April 1976, 6 (4): 292–5. PMID 825374. doi:10.1002/eji.1830060411.
Köhler G, Milstein C. Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion. Eur. J. Immunol. July 1976, 6 (7): 511–9. PMID 825377. doi:10.1002/eji.1830060713.
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Hagberg H, Glimelius B, Gronowitz JS, Killander A, Källander CFR, Schröder T. Biochemical markers in non-Hodgkin's lymphoma stages III and IV and prognosis: a multivariate analysis. Scand J Haematol. July 1984, 33 (1): 59–67. PMID 6379852. doi:10.1111/j.1600-0609.1984.tb02211.x.
Hallek M, Wanders L, Strohmeyer S, Emmerich B. Thymidine kinase: a tumor marker with prognostic value for non-Hodgkin's lymphoma and a broad range of potential clinical applications. Ann. Hematol. July 1992, 65 (1): 1–5. PMID 1643153. doi:10.1007/BF01715117.
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Suki S, Swan F, Tucker S; et al. Risk classification for large cell lymphoma using lactate dehydrogenase, beta-2 microglobulin, and thymidine kinase. Leuk. Lymphoma. June 1995, 18 (1–2): 87–92. PMID 8580834. doi:10.3109/10428199509064927. 引文格式1维护:显式使用等标签 (link)
Hallek M, Wanders L, Ostwald M; et al. Serum beta(2)-microglobulin and serum thymidine kinase are independent predictors of progression-free survival in chronic lymphocytic leukemia and immunocytoma. Leuk. Lymphoma. August 1996, 22 (5–6): 439–47. PMID 8882957. doi:10.3109/10428199609054782. 引文格式1维护:显式使用等标签 (link)
Källander CFR, Simonsson B, Gronowitz JS, Nilsson K. Serum deoxythymidine kinase correlates with peripheral lymphocyte thymidine uptake in chronic lymphocytic leukemia. Eur. J. Haematol. April 1987, 38 (4): 331–7. PMID 3609253. doi:10.1111/j.1600-0609.1987.tb00007.x.
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Prusoff WH. Synthesis and biological activities of iododeoxyuridine, an analog of thymidine. Biochim. Biophys. Acta. March 1959, 32 (1): 295–6. PMID 13628760. doi:10.1016/0006-3002(59)90597-9.
Morgenroth A, Deisenhofer S, Glatting G; et al. Preferential Tumor Targeting and Selective Tumor Cell Cytotoxicity of 5-[131/125I]Iodo-4'-Thio-2'-Deoxyuridine. Clin. Cancer Res. November 2008, 14 (22): 7311–9. PMID 19010846. doi:10.1158/1078-0432.CCR-08-0907. 引文格式1维护:显式使用等标签 (link)
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Barth RF, Yang W, Al-Madhoun AS; et al. Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors. Cancer Res. September 2004, 64 (17): 6287–95. PMID 15342417. doi:10.1158/0008-5472.CAN-04-0437. 引文格式1维护:显式使用等标签 (link)
Al-Madhoun AS, Johnsamuel J, Barth RF, Tjarks W, Eriksson S. Evaluation of human thymidine kinase 1 substrates as new candidates for boron neutron capture therapy. Cancer Res. September 2004, 64 (17): 6280–6. PMID 15342416. doi:10.1158/0008-5472.CAN-04-0197.
Johnsamuel J, Lakhi N, Al-Madhoun AS; et al. Synthesis of ethyleneoxide modified 3-carboranyl thymidine analogues and evaluation of their biochemical, physicochemical, and structural properties. Bioorg. Med. Chem. September 2004, 12 (18): 4769–81. PMID 15336255. doi:10.1016/j.bmc.2004.07.032. 引文格式1维护:显式使用等标签 (link)
Byun Y, Yan J, Al-Madhoun AS; et al. The synthesis and biochemical evaluation of thymidine analogues substituted with nido carborane at the N-3 position. Appl Radiat Isot. November 2004, 61 (5): 1125–30. PMID 15308203. doi:10.1016/j.apradiso.2004.05.023. 引文格式1维护:显式使用等标签 (link)
Gronowitz JS, Källander FR, Diderholm H, Hagberg H, Pettersson U. Application of an in vitro assay for serum thymidine kinase: results on viral disease and malignancies in humans. Int. J. Cancer. January 1984, 33 (1): 5–12. PMID 6693195. doi:10.1002/ijc.2910330103.
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