La Plata is a city in Macon County, Missouri, United States. The population was 1,257 at the 2020 census. La Plata is located next to the Adair County line and is on a mainline of the BNSF Railway. The town is best known for La Plata station, which provides passenger rail service to Chicago and Los Angeles. The beginnings of La Plata can be traced back to March 17, 1827 when Drury Davis established a trading post near the town's current location. The ensuing few years saw Davis joined by family and friends to create a small village that included a blacksmith shop, an inn, and stagecoach station. More information...
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