San Luis is a city in Yuma County, Arizona, United States. The population was 25,505 at the 2010 census. It is part of the Yuma Metropolitan Statistical Area. San Luis, located in the southwest corner of the state directly adjacent to Mexico's Federal Highway 2 at San Luis Rio Colorado, was the second fastest-growing city or town in Arizona from 1990 to 2000. According to 2019 Census Bureau estimates, the population of the city is 34,778. The city was established in 1930 with the opening of a border-crossing station. In the last twenty years it has registered an accelerated population increase, going from 1,946 inhabitants in 1980, to approximately 20,000 in the year 2005. The city annexed over 16,000 acres (65 km2) of land between 2006 and 2012, thereby increasing the availability of land for residential, commercial and industrial growth in the eastern part of town where the new commercial port of entry will be constructed. More information...
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