Midazolam and pentobarbital for refractory status epilepticus.Holmes, GL & Riviello Jr., JJ. (1999) Elsevier Science Inc. Pediatric Neurology. 20(4), April 1999. pp.: 259 – 264. ...Although initial therapies with agents such as diazepam, phenytoin, or phenobarbital generally terminate seizure activity within 30 – 60 minutes, patients with refractory status epilepticus (RSE) lasting longer require additional intervention. High-dose pentobarbital has been the most commonly prescribed agent for the management of RSE in children...www.sciencedirect.com