Eur J Pharmacol. 2009 Oct 22. [Epub ahead of print]
Luteolin, a non-selective competitive inhibitor of phosphodiesterases 1-5, displaced [(3)H]-rolipram from high-affinity rolipram binding sites and reversed xylazine/ketamine-induced anesthesia.
Yu MC, Chen JH, Lai CY, Han CY, Ko WC. PMID: 19853596