References analysis of the Wikipedia article "Blut-Hirn-Schranke" in the German version

IABotmemento.invalid

doi.org

S. Wolf et al.: Die Blut-Hirn-Schranke: Eine Besonderheit des cerebralen Mikrozirkulationssystems. In: Naturwissenschaften 83, 1996, S. 302–311. doi:10.1007/BF01152211.

R. Kaliszan und M. Markuszewski: Brain/blood distribution described by a combination of partition coefficient and molecular mass. In: International Journal of Pharmaceutics 145, 1996, S. 9–16. doi:10.1016/S0378-5173(96)04712-6.

I. Tamai, A. Tsuji: Drug delivery through the blood-brain barrier. In: Adv Drug Deliv Rev 19, 1996, S. 401–424. doi:10.1016/0169-409X(96)00011-7 (Review).

jbc.org

jdentaled.org

M. Kotlyar und D. K. Hatsukami: Managing nicotine addiction. (Memento des Originals vom 6. Juli 2008 im Internet Archive) Info: Der Archivlink wurde automatisch eingesetzt und noch nicht geprüft. Bitte prüfe Original- und Archivlink gemäß Anleitung und entferne dann diesen Hinweis. In: J Dent Educ 66, 2002, S. 1061–1073. PMID 12374267.

nbn-resolving.de

I. Sauer: Apolipoprotein E abgeleitete Peptide als Vektoren zur Überwindung der Blut-Hirn-Schranke. Dissertation FU Berlin, 2004. urn:nbn:de:kobv:188-2004003141

A. Elbert: Die Permeation kleiner polarer Moleküle durch Phospholipidmodellmembranen. Dissertation, Universität Kaiserslautern, 1999. urn:nbn:de:bsz:386-kluedo-12797

D. Magnani: Untersuchungen der Fremdstoffbindung in permanenten Keratinozyten- und Melanozyten-Zelllinien sowie die Eignung von Primärkulturen aus humanen Haarfollikeln zur In-vitro-Messung der Fremdstoffaufnahme im Haar. Dissertation, Carl von Ossietzky Universität Oldenburg, 2005. urn:nbn:de:gbv:715-oops-1151

nih.gov

ncbi.nlm.nih.gov

W. Risau et al.: Immune function of the blood-brain barrier: in complete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro. In: Journal of Cell Biology 110, 1990, S. 1757–1766. PMID 1692329.

S. Ohtsuki: New aspects of the blood-brain barrier transporters; its physiological roles in the central nervous system. In: Biol Pharm Bull. 27, 2004, S. 1489–1496. PMID 15467183 (Review).

M. Bundgaard. N. J. Abbott: All vertebrates started out with a glial blood-brain barrier 4-500 million years ago. In: Glia. 56, 2008, S. 699–708. PMID 18338790.

W. M. Pardridge: Molecular biology of the blood–brain barrier. In: Mol Biotechnol, 30, 2005, S. 57–69. PMID 15805577 (Review).

J. Cervos-Navarro: Elektronenmikroskopische Befunde an den Kapillaren der Hirnrinde. In: Arch Psychiatr Nervenkr 204, 1963, S. 484–504. PMID 14082797.

B. T. Hawkins und T. P. Davis: The blood-brain barrier/neurovascular unit in health and disease. In: Pharmacol Rev 57, 2005, S. 173–185. PMID 15914466 (Review).

R. S. el-Bacha, A. Minn: Drug metabolizing enzymes in cerebrovascular endothelial cells afford a metabolic protection to the brain. In: Cell Mol Biol 45, 1999, S. 15–23. PMID 10099836 (Review).

M. Chat et al.: Drug metabolizing enzyme activities and superoxide formation in primary and immortalized rat brain endothelial cells. In: Life Sci 62, 1998, S. 151–163. PMID 9488113.

A. Minn et al.: Drug metabolizing enzymes in the brain and cerebral microvessels. In: Brain Res Brain Res Rev 116, 1991, S. 65–82. PMID 1907518 (Review).

Y. Takahura et al.: Blood-brain barrier: transport studies in isolated brain capillaries and in cultured brain endothelial cells. In: Adv Pharmacol 22, 1991, S. 137–165. PMID 1958501 (Review).

S. Meresse et al.: Bovine brain endothelial cells expres tight junctions and monoamine oxidase activity in long-term culture. In: J Neurochem 53, 1989, S. 1363–1371. PMID 2571674.

R. Perrin et al.: Distribution of cytochrom P450 activities towards alkoxyresorufin derivates in rat brain regions, subcellular fractions and isolated cerebral microvessels. In: Biochem Pharmacol 40, 1990, S. 2145–2151. PMID 2242042.

R. Bendayan et al.: Functional expression and localization of P-glycoprotein at the blood brain barrier. In: Microsc Res Tech 57, 2002, S. 365–380. PMID 12112443 (Review).

Y. Su, P. J. Sinko: Drug delivery across the blood-brain barrier: why is it difficult? how to measure and improve it? In: Expert Opin Drug Deliv 3, 2006, S. 419–435. PMID 16640501 (Review).

H. Fischer et al.: Blood–brain barrier permeation: molecular parameters governing passive diffusion. In: J Membr Biol 165, 1998, S. 201–211. PMID 9767674.

U. Fagerholm: The highly permeable blood–brain barrier: an evaluation of current opinions about brain uptake capacity. In: Drug Discovery Today 12, 2007, S. 1076–1082. PMID 18061888 (Review).

B. Nico et al.: Role of aquaporin-4 water channel in the development and integrity of the blood-brain barrier. In: J Cell Sci 114, 2001, S. 1297–1307. PMID 11256996.

A. M. Butt et al.: Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study. In: J Physiol 429, 1990, S. 47–62. PMID 2277354.

P. Claude, D. A. Goodenough: Fracture faces of zonae occludentes from tight and leaky epithelia. In: J Cell Biol, 58, 1973, S. 390–400. PMID 4199658.

H. Wolburg et al.: Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes. In: J Cell Sci 107, 1994, S. 1347–1357. PMID 7929640.

H. B. Newton: Advances in strategies to improve drug delivery to brain tumors. In: Expert Rev Neurother 6, 2006, S. 1495–1509. PMID 17078789 (Review).

J. L. Madara: Tight junction dynamics: is paracellular transport regulated? In: Cell 53, 1988, S. 497–498. PMID 3286009.

R. Cecchell et al.: Modelling of the blood–brain barrier in drug discovery and development. In: Nat Rev Drug Discov, 6, 2007, S. 650–661. PMID 17667956 (Review).

K. Matter, M. S. Balda: Holey barrier: claudins and the regulation of brain endothelial permeability. In: J Cell Biol, 161, 2003, S. 459–460. PMID 12743096 (Review).

T. Nitta et al.: Size-selective loosening of the blood–brain barrier in claudin-5-deficient mice. In: J Cell Biol, 161, 2003, S. 653–660. PMID 12743111.

P. Dore-Duffy: Pericytes: pluripotent cells of the blood brain barrier. In: Curr Pharm Des 14, 2008, S. 1581–1593. PMID 18673199 (Review).

R. Balabanov, P. Dore-Duffy: Role of the CNS microvascular pericyte in the blood-brain barrier. In: J Neurosci Res 53, 1998, S. 637–644. PMID 9753191 (Review).

H.K. Rucker et al.: Cellular mechanisms of CNS pericytes. In: Brain Res Bull 51, 2000, S. 363–369. PMID 10715555 (Review).

N. J. Abbott: Neurobiology: Glia and the blood-brain barrier. In: Nature, 325, 1987, S. 195. PMID 3808015.

C. H. Lai, K. H. Kuo: The critical component to establish in vitro BBB model: Pericyte. In: Brain Res Brain Res Rev, 50, 2005, S. 258–265. PMID 16199092 (Review).

D. Shepro, N.M. Morel: Pericyte physiology. In: FASEB J, 7, 1993, S. 1031–1038. PMID 8370472 (Review).

K. Fujimoto: Pericyte-endothelial gap junctions in developing rat cerebral capillaries: A fine structural study. In: Anat Rec 242, 1995, S. 562–565. PMID 7486026.

L. Diaz-Flores: Microvascular pericytes: A review of their morphological and functional characteristics. In: Histol Histopath 6, 1991, S. 269–286. PMID 1802127 (Review).

D. E. Sims: Recent advances in pericyte biology—Implications for health and disease. In: Can J Cardiol 7, 1991, S. 431–443. PMID 1768982 (Review).

D. E. Sims: Diversity within pericytes. In: Clin Exp Pharmacol Physiol 27, 2000, S. 842–846. PMID 11022980 (Review).

I. M. Herman, P. A. D’Amore: Microvascular pericytes contain muscle and nonmuscle actins. In: J Cell Biol, 101, 1985, S. 43–52. PMID 3891763.

K. K. Hirschi, P. A. D’Amore: Pericytes in the microvasculature. In: Cardiovasc Res, 32, 1996, S. 687–698. PMID 8915187 (Review).

M. Mato et al.: Evidence for the possible function of the fluorescent granular perithelial cells in brain as scavengers of high-molecular-weight waste products. In: Experientia 40, 1984, S. 399–402. PMID 6325229.

R. Balabanov et al.: CNS microvascular pericytes express macrophage-like function, cell surface integrin alphaM, and macrophage marker ED-2. In: Microvasc Res 52, 1996, S. 127–142. PMID 8901442.

W. F. Hickey und H. Kimura: Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. In: Science 239, 1988, S. 290–292. PMID 3276004.

Z. Fabry et al.: Differential activation of Th1 and Th2 CD4+ cells by murine brain microvessel endothelial cells and smooth muscle/pericytes. In: J Immunol 151, 1993, S. 38–47. PMID 8100844.

D. Krause et al.: Cerebral pericytes – a second line of defense in controlling blood-brain barrier peptide metabolism. In: Adv Exp Med Biol 331, 1993, S. 149–152. PMID 8101424.

W. E. Thomas: Brain macrophages: on the role of pericytes and perivascular cells. In: Brain Res Brain Res Rev 31, 1999, S. 42–57. PMID 10611494 (Review).

C. Iadecola: Neurovascular regulation in the normal brain and in Alzheimer’s disease. In: Nat Rev Neurosci 5, 2004, S. 347–360. PMID 15100718 (Review).

B. Engelhardt: Development of the blood-brain barrier. In: Cell Tissue Res 314, 2003, S. 119–129. PMID 12955493 (Review).

C. E. Johanson: Permeability and vascularity of the developing brain: cerebellum vs. cerebral cortex. In: Brain Res 190, 1980, S. 3–16. PMID 6769537.

J. Neuhaus et al.: Induction of blood-brain barrier characteristics in bovine brain endothelial cells by rat astroglial cells in transfilter coculture. In: Ann N Y Acad Sci 633, 1991, S. 578–580. PMID 1789585.

P. A. Stewart, M. J. Wiley: Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: a study using quail–chick transplantation chimeras. In: Dev Biol, 84, 1981, S. 183–192. PMID 7250491.

T. J. Raub et al.: Permeability of bovine brain microvessel endothelial cells in vitro: barrier tightening by a factor released from astroglioma cells. In: Exp Cell Res, 199, 1992, S. 330–340. PMID 1347502.

N. J. Abbott: Astrocyte-endothelial interactions and blood-brain barrier permeability. In: J Anat 200, 2002, S. 629–638. PMID 12162730 (Review).

O. B. Paulson, E. A. Newman: Does the release of potassium from astrocyte endfeet regulate cerebral blood flow? In: Science, 237, 1987, S. 896–898. PMID 3616619.

N. J. Abbott et al.: Astrocyte-endothelial interactions at the blood-brain barrier. In: Nat Rev Neurosci, 7, 2006, S. 41–53. PMID 16371949 (Review).

I. Björkhem, S. Meaney: Brain Cholesterol: Long Secret Life Behind a Barrier. In: Arterioscler Thromb Vasc Biol, 24, 2004, S. 806–815. PMID 14764421 (Review).

H. M. Duvernoy, P. Y. Risold: The circumventricular organs: an atlas of comparative anatomy and vascularization. In: Brain Res Rev 56, 2007, S. 119–147. PMID 17659349 (Review).

W. L. Chiou, A. Barve: Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats. In: Pharm Res, 15, 1998, S. 1792–1795. PMID 9834005.

J. T. Goodwin und D. E. Clark: In silico predictions of blood-brain barrier penetration: considerations to "keep in mind". In: J Pharmacol Exp Ther 315, 2005, S. 477–483. PMID 15919767 (Review).

S. L. Lindstedt und P. J. Schaeffer: Use of allometry in predicting anatomical and physiological parameters of mammals. In: Lab Anim 36, 2002, S. 1–19. PMID 11833526.

R. W. Leggett, L. R. Williams: A proposed blood circulation model for reference man. In: Health Phys, 69, 1995, S. 187–201. PMID 7622365.

S. Willmann et al.: A physiological model for the estimation of the fraction dose absorbed in humans. In: J Med Chem 47, 2004, S. 4022–4031. PMID 15267240.

U. Fagerholm et al.: Comparison between permeability coefficients in rat and human jejunum. In: Pharm Res, 13, 1996, S. 1336–1342. PMID 8893271.

R. W. Leggett, L. R. Williams: Suggested reference values for regional blood volumes in humans. In: Health Phys, 60, 1991, S. 139–154. PMID 1989937.

S. Wakai, N. Hirokawa: Development of the blood–brain barrier to horseradish peroxidase in the chick embryo. In: Cell Tissue Res, 195, 1979, S. 195–203. PMID 737715.

W. Risau et al.: Differentiation-dependent expression of proteins in brain endothelium during development of the blood–brain barrier. In: Dev Biol 117, 1986, S. 537–545. PMID 2875908.

M. L. Reynolds et al.: Intracranial haemorrhage in the preterm sheep fetus. In: Early Hum Dev 3, 1979, S. 163–186. PMID 575326.

N. R. Saunders et al.: Barrier mechanisms in the brain, II. Immature brain. In: Clin Exp Pharmacol Physiol 26, 1999, S. 85–91. PMID 10065326 (Review).

U. Schumacher, K. Møllgård: The multidrug resistance P-glycoprotein (Pgp, MDR1) is an early marker of blood–brain barrier development in the microvessels of the developing human brain. In: Histochem Cell Biol, 108, 1997, S. 179–182. PMID 9272437.

K. M. Dziegielewska et al.: Studies of the development of brain barrier systems to lipid insoluble molecules in fetal sheep. In: J Physiol, 292, 1979, S. 207–231. PMID 490348.

R. K. Ferguson, D. M. Woodbury: Penetration of 14C-inulin and 14C-sucrose into brain, cerebrospinal fluid and skeletal muscle of developing rats. In: Exp Brain Res, 7, 1969, S. 181–194. PMID 5795246.

M. D. Habgood et al.: The nature of the decrease in blood–cerebrospinal fluid barrier exchange during postnatal brain development in the rat. In: J Physiol 468, 1993, S. 73–83. PMID 8254533.

L. D. Braun et al.: Newborn rabbit blood–brain barrier is selectively permeable and differs substantially from the adult. In: J Neurochem 34, 1980, S. 147–152. PMID 7452231.

E. M. Cornford et al.: Developmental modulations of blood–brain barrier permeability as an indicator of changing nutritional requirements in the brain. In: Pediatr Res 16, 1982, S. 324–328. PMID 7079003.

D. P. Brenton, R. M. Gardiner: Transport of L-phenylalanine and related amino acids at the ovine blood–brain barrier. In: J Physiol, 402, 1988, S. 497–514. PMID 3236248.

H. J. L. Frank et al.: Enhanced insulin binding to blood–brain barrier in vivo and to brain microvessels in vitro in newborn rabbits. In: Diabetes, 34, 1985, S. 728–733. PMID 3894116.

N. R. Saunders: Barriers in the immature brain. In: Cell Mol Neurobiol, 20, 2000, S. 29–40. PMID 10690500 (Review).

N. J. Abbott, M. Bundgaard: Electron-dense tracer evidence for a blood-brain barrier in the cuttlefish, Sepia officinalis. In: J Neurocytol, 21, 1992, S. 276–294. PMID 1588347.

N. J. Abbott, Y. Pichon: The glial blood-brain barrier of crustacea and cephalopods: a review. In: J Physiol (Paris), 82, 1987, S. 304–313. PMID 3332691 (Review).

N. J. Abbott: Dynamics of CNS barriers: evolution, differentiation, and modulation. In: Cell Mol Neurobiol 25, 2005, S. 5–23. PMID 15962506 (Review).

T. Stork et al.: Organization and function of the blood-brain barrier in Drosophila. In: J Neurosci 28, 2008, S. 587–597. PMID 18199760.

J. Fraher und E. Cheong: Glial-Schwann cell specialisations at the central-peripheral nervous system transition of a cyclostome: An ultrastructural study. In: Acta Anat 154, 1995, S. 300–314. PMID 8773716.

F. Miragall et al.: Expression of the tight junction protein ZO-1 in the olfactory system: Presence of ZO-1 on olfactory sensory neurons and glial cells. In: J Comp Neurol 341, 1994, S. 433–448. PMID 8201022.

R. D. Egleton, T. P. Davis: Development of neuropeptide drugs that cross the blood-brain barrier. In: NeuroRx 2, 2005, S. 44–53. PMID 15717056 (Review).

W. H. Oldendorf: Lipid solubility and drug penetration of the blood-brain barrier. In: Proc Soc Exp Biol Med 147, 1974, S. 813–816. PMID 4445171.

H. Träuble: Carriers and specificity in membranes. 3. Carrier-facilitated transport. Kinks as carriers in membranes. In: Neurosci Res Program Bull 9, 1971, S. 361–372. PMID 5164654.

H. Träuble: Phasenumwandlungen in Lipiden. Mögliche Schaltprozesse in biologischen Membranen. In: Naturwissenschaften 58, 1971, S. 277–284. PMID 4935458 (Review).

A. Seelig und J. Seelig: The dynamic structure of fatty acyl chains in a phospholipid bilayer measured by deuterium magnetic resonance. In: Biochemistry 13, 1974, S. 4839–4845. PMID 4371820.

V. A. Levin: Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. In: J Med Chem 23, 1980, S. 682–684. PMID 7392035.

A. Seelig et al.: A method to determine the ability of drugs to diffuse throught the blood-brain barrier. In: PNAS 91, 1994, S. 68–72. PMID 8278409.

G. A. Dhopeshwarkar und J. F. Mead: Uptake and transport of fatty acids into the brain and the role of the blood-brain barrier system. In: Adv Lipid Res 11, 1973, S. 109–142. PMID 4608446 (Review).

G. Gerebtzoff, A. Seelig: In silico prediction of blood-brain barrier permeation using the calculated molecular cross-sectional area as main parameter. In: A J Chem Inf Model, 46, 2006, S. 2638–2650. PMID 17125204.

W. W. Pardridge: The blood-brain barrier: bottleneck in brain drug development. In: NeuroRx 2, 2005, S. 3–14. PMID 15717053 (Review).

W. H. Oldendorf: Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard. In: Brain Res, 24, 1970, S. 372–376. PMID 5490302.

D. Dolman et al.: Induction of aquaporin 1 but not aquaporin 4 messenger RNA in rat primary brain microvessel endothelial cells in culture. In: J Neurochem 93, 2005, S. 825–833. PMID 15857386.

O. Bloch und G. T. Manley: The role of aquaporin-4 in cerebral water transport and edema. In: Neurosurg Focus 22, 2007, S. E3 PMID 17613234 (Review).

A. S. Verkman: More than just water channels: unexpected cellular roles of aquaporins. In: J Cell Sci 118, 2005, S. 3225–3232. PMID 16079275 (Review).

J. Badaut et al.: Aquaporins in the brain: from aqueduct to "multi-duct". In: Metab Brain Dis 22, 2007, S. 251–263. PMID 17701333 (Review).

A. Dahlin, J. Royall, J. G. Hohmann, J. Wang: Expression Profiling of the Solute Carrier (SLC) Gene Family in the Mouse Brain. In: J. Pharmacol. Exp. Ther. 329, 2009, S. .558–570 PMID 19179540 PMC 267287 (freier Volltext).

D. Agus et al.: Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters. In: J Clin Invest 100, 1997, S. 2842–2848. PMID 9389750.

E. M. Cornford und S. Hyman: Blood-brain barrier permeability to small and large molecules. In: Advanced Drug Delivery Reviews 36, 1999, S. 145–163. PMID 10837713 (Review).

B. V. Zlokovic et al.: Transport of leucine-enkephalin across the blood-brain barrier in the perfused guinea pig brain. In: J Neurochem 49, 1987, S. 310–315. PMID 3585338.

B. V. Zlokovic et al.: Kinetic analysis of leucine-enkephalin cellular uptake at the luminal side of the blood-brain barrier of an in situ perfused guinea-pig brain. In: J Neurochem 53, 1989, S. 1333–1340. PMID 2795003.

B. V. Zlokovic et al.: Kinetics of arginine-vasopressin uptake at the bloodbrain barrier. In: Biochim Biophys Acta 1025, 1990, S. 191–198. PMID 2364078.

S. A. Thomas et al.: The entry of [D-penicillamine2,5]enkephalin into the central nervous system: saturation kinetics and specificity. In: J Pharmacol Exp Ther 280, 1997, S. 1235–1240. PMID 9067309.

V. V. Rao et al.: Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier. In: PNAS 96, 1999, S. 3900–3905. PMID 10097135.

F. Thiebaut et al.: Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries. In: J Histochem Cytochem 37, 1989, S. 159–164, PMID 2463300.

D. J. Begley: ABC transporters and the blood-brain barrier. In: Curr Pharm Des 10, 2004, S. 1295–1312. PMID 15134482 (Review).

S. Seetharaman et al.: Multidrug resistance-related transport proteins in isolated human brain microvessels and in cells cultured from these isolates. In: J Neurochem 70, 1998, S. 1151–1159. PMID 9489736.

H. C. Cooray et al.: Localisation of breast cancer resistance protein in microvessel endothelium of human brain. In: Neuroreport 13, 2002, S. 2059–2063. PMID 12438926.

T. Eisenblätter und H. J. Galla: A new multidrug resistance protein at the blood-brain barrier. In: Biochem Biophys Res Commun 293, 2002, S. 1273–1278. PMID 12054514.

Y. Tanaka et al.: Ultrastructural localization of P-glycoprotein on capillary endothelial cells in human gliomas. In: Virchows Arch 425, 1994, S. 133–138. PMID 7952498.

E. C. de Lange: Potential role of ABC transporters as a detoxification system at the blood-CSF barrier. In: Adv Drug Deliv Rev 56, 2004, S. 1793–1809. PMID 15381334 (Review).

H. Wolosker et al.: Neurobiology through the looking-glass: D-serine as a new glial-derived transmitter. In: Neurochem Int, 41, 2002, S. 327–332. PMID 12176074 (Review).

C. F. Zorumski und J. W. Olney: Excitotoxic neuronal damage and neuropsychiatric disorders In: Pharmacol Ther 59, 1993, S. 145–162. PMID 7904075 (Review).

K. Hosoya et al.: Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. In: J Neurochem, 73, 1999, S. 1206–1211. PMID 10461913.

M. Palacin et al.: Molecular biology of mammalian plasma membrane amino acid transporters. In: Physiol Rev, 78, 1998, S. 969–1054. PMID 9790568 (Review).

W. Löscher und H. Potschka: Blood-brain barrier active efflux transporters: ATP-binding cassette gene family. In: NeuroRx, 2, 2005, S. 86–98. PMID 15717060 (Review).

D. M. Tishler et al.: MDR1 gene expression in brain of patients with medically intractable epilepsy. In: Epilepsia, 36, 1995, S. 1–6. PMID 8001500.

H. Kusuhara et al.: Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain. (Memento des Originals vom 29. April 2008 im Internet Archive) Info: Der Archivlink wurde automatisch eingesetzt und noch nicht geprüft. Bitte prüfe Original- und Archivlink gemäß Anleitung und entferne dann diesen Hinweis. In: J Biol Chem, 274, 1999, S. 13675–13680. PMID 10224140.

B. Gao et al.: Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain. (Memento vom 5. September 2008 im Internet Archive) In: J Histochem Cytochem, 47, 1999, S. 1255–1264. PMID 10490454.

L. Z. Bito: Blood-Brain Barrier: Evidence for Active Cation Transport between Blood and the Extraceliular Fluid of Brain. In: Science 165, 1969, S. 81–83. PMID 17840696.

Y. Kido et al.: Functional relevance of carnitine transporter OCTN2 to brain distribution of L-carnitine and acetyl-L-carnitine across the blood-brain barrier. In: J Neurochem 79, 2001, S. 959–969. PMID 11739607.

R. L. Roberts et al.: Receptor-mediated endocytosis of transferrin at the blood-brain barrier. In: J Cell Sci 104, 1993, S. 521–532. PMID 8505377.

B. Dehouck et al.: Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes. In: J Cell Biol 126, 1994, S. 465–473. PMID 8034745.

K. R. Duffy et al.: Human blood-brain barrier insulin-like growth factor receptor. In: Metabolism 37, 1988, S. 136–140. PMID 2963191.

M. W. Smith und M. Gumbleton: Endocytosis at the blood-brain barrier: from basic understanding to drug delivery strategies. In: J Drug Target 14, 2006, S. 191–214. PMID 16777679 (Review).

F. Hervé et al.: CNS delivery via adsorptive transcytosis. In: AAPS J 10, 2008, S. 455–472. PMID 18726697 (Review).

J. M. Scherrmann: Drug delivery to brain via the blood-brain barrier. In: Vascul Pharmacol 38, 2002, S. 349–354. PMID 12529929 (Review).

I. Tamai et al.: Structure-internalization relationship for adsorptive-mediated endocytosis of basic peptides at the blood– brain barrier. In: J Pharmacol Exp Ther 280, 1997, S. 410–415. PMID 8996222.

W. M. Pardridge: Blood-brain barrier delivery. In: Drug Discov Today 12, 2007, S. 54–61. PMID 17198973.

H. Bronger et al.: ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier. In: Cancer Res 65, 2005, S. 11419–11428. PMID 16357150.

H. Kusuhara und Y. Sugiyama: Active efflux across the blood-brain barrier: role of the solute carrier family. In: NeuroRx 2, 2005, S. 73–85. PMID 15717059 (Review).

J. M. Scherrmann: Expression and function of multidrug resistance transporters at the blood-brain barriers. In: Expert Opin Drug Metab Toxicol 1, 2005, S. 233–246. PMID 16922639 (Review).

N. Bodor und P. Buchwald: Recent advances in the brain targeting of neuropharmaceuticals by chemical delivery systems. In: Adv Drug Deliv Rev 36, 1999, S. 229–254. PMID 10837718 (Review).

U. Bickel: How to measure drug transport across the blood-brain barrier. In: NeuroRx 2, 2005, S. 15–26. PMID 15717054 (Review).

A. M. Peters: Fundamentals of tracer kinetics for radiologists. In: Br J Radiol 71, 1998, S. 1116–1129. PMID 10434905 (Review).

F. Lasbennes et al.: Capacity for energy metabolism in microvessels isolated from rat brain. In: Neurochem Res 9, 1984, S. 1–10. PMID 6325972.

J. Huwyler und W. M. Pardridge: Examination of blood-brain barrier transferrin receptor by confocal fluorescent microscopy of unfixed isolated rat brain capillaries. In: J Neurochem 70, 1998, S. 883–886. PMID 9453586.

D. S. Miller et al.: Xenobiotic transport across isolated brain microvessels studied by confocal microscopy. In: Mol Pharmacol 58, 2000, S. 1357–1367. PMID 11093774.

M. Gumbleton et al.: Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier. In: J Pharm Sci 90, 2001, S. 1681–1698. PMID 11745727 (Review).

A. Reichel et al.: An overview of in vitro techniques for blood-brain barrier studies. In: Methods Mol Med 89, 2003, S. 307–324. PMID 12958429.

R. Cecchelli et al.: In vitro model for evaluating drug transport across the blood-brain barrier. In: Adv Drug Deliv Rev 36, 1999, S. 165–178. PMID 10837714.

D. Hoheisel et al.: Hydrocortisone reinforces the blood-brain properties in a serum free cell culture system. In: Biochem Biophys Res Commun 247, 1998, S. 312–315. PMID 9679029.

S. B. Raymond et al.: Ultrasound Enhanced Delivery of Molecular Imaging and Therapeutic Agents in Alzheimer’s Disease Mouse Models. In: PLoS ONE 3, 2008, e2175. PMID 18478109.

J. D. Fenstermacher et al.: Methods for quantifying the transport of drugs across the blood-brain system. In: Pharmacol Ther 14, 1981, S. 217–248. PMID 7031708.

J. E. Hardebo, B. Nilsson: Estimation of cerebral extraction of circulating compounds by the brain uptake index method: influence of circulation time, volume injection, and cerebral blood flow. In: Acta Physiol Scand 107, 1979, S. 153–159. PMID 525379.

Y. Moriki et al.: Involvement of P-glycoprotein in blood-brain barrier transport of pentazocine in rats using brain uptake index method. In: Biol Pharm Bull 27, 2004, S. 932–935. PMID 15187451.

L. J. Murphey und G. D. Olsen: Diffusion of morphine-6-beta-D-glucuronide into the neonatal guinea pig brain during drug-induced respiratory depression. In: J Pharmacol Exp Ther 271, 1994, S. 118–124. PMID 7965704.

W. H. Oldendorf et al.: Blood-brain barrier penetration abolished by N-methyl quaternization of nicotine. In: PNAS 90, 1993, S. 307–311. PMID 8419935.

E. M. Cornford et al.: Comparison of lipid-mediated blood-brain-barrier penetrability in neonates and adults. In: Am J Physiol-Cell Physiol 243, 1982, S. 161C–168C. PMID 7114247.

B. V. Zlokovic et al.: Measurement of solute transport in the perfused guinea pig brain. Method application to N-methyl-alpha-aminoisobutyric acid. In: J Neurochem 46, 1986, S. 1444–1451. PMID 3083044.

D. Triguero et al.: Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins. In: J Neurochem 54, 1990, S. 1882–1888. PMID 2338547.

C. Crone: The permeability of capillaries in various organs as determined by use of the 'Indicator Diffusion' method. In: Acta Physiol Scand 58, 1963 S. 292–305. PMID 14078649.

J. B. van Bree et al.: Drug transport across the blood-brain barrier, II. Experimental techniques to study drug transport. In: Pharma Weekbl Sci 14, 1992, S. 338–348. PMID 1475172 (Review).

L. Sokoloff et al.: The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. In: J Neurochem 28, 1977, S. 897–916. PMID 864466.

E. C. M. de Lange et al.: The use of intacerebral microdialysis to determine the changes in blood-brain barrier transport characteristics. In: Pharm Res 12, 1995, S. 129–133. PMID 7724474.

E. C. M. de Langeet al.: Critical factors of intracerebral microdialysis as a technique to determine the pharmacokinetics of drugs in rat brain. In: Brain Res 666, 1994, S. 1–8. PMID 7889356.

E. C. M. de Lange et al.: Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood-brain barrier. In: Brain Res Brain Res Rev 25, 1997, S. 27–49. PMID 9370049 (Review).

E. C. M. de Lange et al.: BBB transport and P-glycoprotein functionality using MDR1A (-/-) and wild-type mice. Total brain versus microdialysis concentration profiles of rhodamine-123. In: Pharm Res 15, 1998, S. 1657–1665. PMID 9833984.

T. Terasaki et al.: In vivo transport of a dynorphin-like analgesic peptide, E 2078, through the blood-brain barrier: an application of microdialysis. In: J Pharmacol Exp Ther 251, 1991, S. 815–820. PMID 1681528.

C. Berger et al.: Zerebrale Mikrodialyse beim Schlaganfall. In: Der Nervenarzt 75, 2004, S. 113–123. PMID 14770280.

S. Syvänen et al.: Species differences in blood-brain barrier transport of three PET radioligands with emphasis on P-glycoprotein transport. In: Drug Metab Dispos 37, 2009, S. 635–643. PMID 19047468.

J. Bart et al.: New positron emission tomography tracer (11)C-carvedilol reveals P-glycoprotein modulation kinetics. In: Br J Pharmacol 145, 2005, S. 1045–1051. PMID 15951832.

N. H. Hendrikse et al.: A new in vivo method to study P-Glycoprotein transport in tumors and the blood-brain barrier. In: Cancer Res 59, 1999, S. 2411–2416. PMID 10344751.

S. S. Zoghbi et al.: 11C-loperamide and its N-desmethyl radiometabolite are avid substrates for brain permeability-glycoprotein efflux. In: J Nucl Med 49, 2008, S. 649–656. PMID 18344435.

V. Josserand et al.: Evaluation of Drug Penetration into the Brain: A Double Study by in Vivo Imaging with Positron Emission Tomography and Using an in Vitro Model of the Human Blood-Brain Barrier. In: J Pharmacol Exp Ther 316, 2006, S. 79–86. PMID 16210395.

D. Matsuzawa et al.: Negative Correlation between Brain Glutathione Level and Negative Symptoms in Schizophrenia: A 3T 1H-MRS Study. In: PLoS ONE 3, 2008, e1944. PMID 18398470.

M. Bartels et al.: 19F Nuclear Magnetic Resonance Spectroscopy of neuroleptics: The first in vivo pharmacokinetics of trifluoperazine in the rat brain and the first in vivo spectrum of fluphenazine in the human brain. In: Biol Psychiatry 30, 1991, S. 656–662. PMID 2386658.

J. J. H. Ackerman et al.: Mapping of metabolites in whole animals by 31P NMR using surface coils. In: Nature 283, 1990, S. 167–170. PMID 7350541.

J. W. Prichard et al.: Cerebral metabolic studies in vivo by 31P NMR. In: PNAS 80, 1983, S. 2748–2751. PMID 6573678.

W. M. Pardridge: Blood-brain barrier drug targeting: the future of brain drug development. In: Mol Interv 3, 2003, S. 90–105. PMID 14993430 (Review).

D. J. Begley: Delivery of therapeutic agents to the central nervous system: the problems and the possibilities. In: Pharmacol Ther, 104, 2004, S. 29–45. PMID 15500907 (Review).

W. M. Pardridge: Why is the global CNS pharmaceutical market so under-penetrated? In: Drug Discovery Today, 7, 2002, S. 5–7. PMID 11790589.

A. G. de Boer, P. J. Gaillard: Strategies to improve drug delivery across the blood-brain barrier. In: Clin Pharmacokinet, 46, 2007, S. 553–576. PMID 17596102 (Review).

A. G. de Boer und P. J. Gaillard: Drug targeting to the brain. In: Annu Rev Pharmacol Toxicol, 47, 2007, S. 323–355. PMID 16961459 (Review).

B. T. Hawkins, R. D. Egleton: Pathophysiology of the blood-brain barrier: animal models and methods. In: Curr Top Dev Biol 80, 2008, S. 277–309. PMID 17950377 (Review).

N. Weiss, F. Miller, S. Cazaubon, P. O. Couraud: The blood-brain barrier in brain homeostasis and neurological diseases. In: Biochim. Biophys. Acta 1788, 2009, S. 842–857 PMID 19061857 (Review).

I. Elmas et al.: Effects of profound hypothermia on the blood-brain barrier permeability in acute and chronically ethanol treated rats. In: Forensic Science International 119, 2001, S. 212–216. PMID 11376985.

S. C. Phillips, B. G. Cragg: Weakening of the blood-brain barrier by alcohol-related stresses in the rat. In: J Neurol Sci, 54, 1982, S. 271–278., PMID 7201507.

A. K. Singh et al.: Effects of chronic ethanol drinking on the blood brain barrier and ensuing neuronal toxicity in alcohol-preferring rats subjected to intraperitoneal LPS injection. In: Alcohol Alcohol, 42, 2007, S. 385–399. PMID 17341516.

J. Haorah et al.: Alcohol-induced blood-brain barrier dysfunction is mediated via inositol 1,4,5-triphosphate receptor (IP3R)-gated intracellular calcium release. In: J Neurochem, 100, 2007, S. 324–336, PMID 17241155.

J. Haorah et al.: Ethanol-induced activation of myosin light chain kinase leads to dysfunction of tight junctions and blood-brain barrier compromise. Alcoholism. In: Clinical and Experimental Research 29, 2005, S. 999–1009. PMID 15976526.

J. Haorah et al.: Alcoholinduced oxidative stress in brain endothelial cells causes bloodbrain barrier dysfunction. (Memento vom 16. März 2010 im Internet Archive) In: Journal of Leukocyte Biology, 78, 2005, S. 1223–1232. PMID 16204625.

R. Peters et al.: Smoking, dementia and cognitive decline in the elderly, a systematic review. In: BMC Geriatr 8, 2008, S. 36. PMID 19105840 (Review).

P. R. Lockman et al.: Brain uptake kinetics of nicotine and cotinine after chronic nicotine exposure. In: J Pharmacol Exp Ther 314, 2005, S. 636–642. PMID 15845856.

T. J. Abbruscato et al.: Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells. In: J Pharm Sci 91, 2002, S. 2525–2538. PMID 12434396.

B. T. Hawkins et al.: Nicotine increases in vivo blood-brain barrier permeability and alters cerebral microvascular tight junction protein distribution. In: Brain Res 1027, 2004, S. 48–58. PMID 15494156.

Y. H. Chen et al.: Enhanced Escherichia coli invasion of human brain microvascular endothelial cells is associated with alternations in cytoskeleton induced by nicotine. In: Cell Microbiol 4, 2002, S. 503–514. PMID 12174085.

P. R. Lockman et al.: Chronic nicotine exposure alters blood-brain barrier permeability and diminishes brain uptake of methyllycaconitine. In: J Neurochem 94, 2005, S. 37–44. PMID 15953347.

P. R. Pentel et al.: A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats. In: Pharmacol Biochem Behav 65, 2000, S. 191–198. PMID 10638653.

D. E. Keyler et al.: Maternal vaccination against nicotine reduces nicotine distribution to fetal brain in rats. In: J Pharmacol Exp Ther 305, 2003, S. 587–592. PMID 12606612.

M. G. LeSage et al.: Effects of a nicotine conjugate vaccine on the acquisition and maintenance of nicotine self-administration in rats. In: Psychopharmacology 184, 2006, S. 409–416. PMID 15991003.

D. A. D’Andrea et al.: Microwave effects on the nervous system. In: Bioelectromagnetics 6, 2003, S. 107–147. PMID 14628310 (Review).

T. H. Patel et al.: Blood brain barrier (BBB) dysfunction associated with increased expression of tissue and urokinase plasminogen activators following peripheral thermal injury. In: Neurosci Lett 444, 2008, S. 222–226. PMID 18718505.

B. R. Persson et al.: Increased permeability of the blood-brain barrier induced by magnetic and electromagnetic fields. In: Ann N Y Acad Sci649, 1992, S. 356–358. PMID 1580510.

L. G. Salford et al.: Nerve cell damage in mammalian brain after exposure to microwaves from GSM mobile phones. In: Environ Health Perspect 111, 2003, S. 881–883. PMID 12782486.

H. Nittby et al.: Radiofrequency and extremely low-frequency electromagnetic field effects on the blood-brain barrier. In: Electromagn Biol Med 27, 2008, S. 103–126. PMID 18568929 (Review).

J. L. Eberhardt et al.: Blood-brain barrier permeability and nerve cell damage in rat brain 14 and 28 days after exposure to microwaves from GSM mobile phones. In: Electromagn Biol Med 27, 2008, S. 215–229. PMID 18821198.

L. G. Salford et al.: Permeability of the blood-brain barrier induced by 915 MHz electromagnetic radiation, continuous wave and modulated at 8, 16, 50, and 200 Hz. In: Microsc Res Tech 27, 1994, S. 535–542. PMID 8012056.

A. Schirmacher et al.: Electromagnetic fields (1.8 GHz) increase the permeability to sucrose of the blood–brain barrier in vitro. In: Bioelectromagnetics 21, 2000, S. 338–345. PMID 10899769.

H. Franke et al.: Electromagnetic fields (GSM 1800) do not alter blood-brain barrier permeability to sucrose in models in vitro with high barrier tightness. In: Bioelectromagnetics 26, 2005, S. 529–535. PMID 16142784.

H. J. Weinmann et al.: Characteristics of Gadolinium-DTPA Complex: A Potential NMR Contrast Agent. In: Am J Roentgenol 142, 1984, S. 619–624. PMID 6607655.

R. C. Brasch et al.: Contrast-enhanced NMR imaging: animal studies using gadolinium-DTPA complex. In: Am J Roentgenol 142, 1984, S. 625–630. PMID 6607656.

V. M. Runge et al.: Visualization of Blood-Brain Barrier Disruption on MR Images of Cats with Acute Cerebral Infarction: Value of Administering a High Dose of Contrast Material. In: AJR Am J Roentgenol 162, 1994, S. 431–435. PMID 8310940.

M. A. Ibrahim et al.: Magnetic resonance imaging relaxation times and gadolinium-DTPA relaxivity values in human cerebrospinal fluid. In: Invest Radiol 33, 1998, S. 153–162. PMID 9525754.

A. V. Alexandrov et al.: Clinical significance of increased uptake of HMPAO on brain SPECT scans in acute stroke. In: J Neuroimaging, 6, 1996, S. 150–155. PMID 8704289 (Review).

J. C. Masdeu, J. Arbizu: Brain single photon emission computed tomography: technological aspects and clinical applications. In: Semin Neurol 28, 2008, S. 423–434. PMID 18843571 (Review).

K. A. Miles: Perfusion CT for the assessment of tumour vascularity: which protocol? In: Br J Radiol 76, 2003, S. 36–42. PMID 15456712.

D. A. Leggett et al.: Blood-brain barrier and blood volume imaging of cerebral glioma using functional CT: a pictorial review. In: Eur J Radiol 30, 1999, S. 185–190. PMID 10452716 (Review).

R. Adam, AC Hüntelmann: Pioneers in Neurology - Edwin Ellen Goldmann. In: J Neurology. Band 270, Nr. 5, 2023, S. 2812–2814, PMID 36976327.

R. D. Tschirgi: Blood-brain barrier: fact or fancy? In: Fed Proc 21, 1962, S. 665–671. PMID 13922779.

G. Miller: Drug targeting. Breaking down barriers. In: Science 297, 2002, S. 1116–1118. PMID 12183610.

T. S. Reese, M. J. Karnovsky: Fine structural localization of a blood-brain barrier to exogenous peroxidase. In: J Cell Biol 34, 1967, S. 207–217. PMID 6033532.

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