R. Barrangou, C. Fremaux, H. Deveau, M. Richards, P. Boyaval, S. Moineau, D. A. Romero, P. Horvath: CRISPR provides acquired resistance against viruses in prokaryotes. In: Science. Band 315, Nummer 5819, März 2007, S. 1709–1712, doi:10.1126/science.1138140, PMID 17379808.
W. Jiang, D. Bikard, D. Cox, F. Zhang, L. A. Marraffini: RNA-guided editing of bacterial genomes using CRISPR-Cas systems. In: Nature Biotechnology. Band 31, Nummer 3, März 2013, S. 233–239, doi:10.1038/nbt.2508, PMID 23360965, PMC 3748948 (freier Volltext).
D. J. Brocken, M. Tark-Dame, R. T. Dame: dCas9: A Versatile Tool for Epigenome Editing. In: Current issues in molecular biology. Band 26, 2018, S. 15–32, doi:10.21775/cimb.026.015, PMID 28879853.
S. E. Mohr, Y. Hu, B. Ewen-Campen, B. E. Housden, R. Viswanatha, N. Perrimon: CRISPR guide RNA design for research applications. In: The FEBS journal. Band 283, Nummer 17, 09 2016, S. 3232–3238, doi:10.1111/febs.13777, PMID 27276584, PMC 5014588 (freier Volltext).
Maeder ML, Linder SJ, Cascio VM, Fu Y, Ho QH, Joung JK: CRISPR RNA-guided activation of endogenous human genes. In: Nature Methods. 10. Jahrgang, Nr.10, Oktober 2013, S.977–9, doi:10.1038/nmeth.2598, PMID 23892898, PMC 3794058 (freier Volltext).
M. Gebre, J. L. Nomburg, B. E. Gewurz: CRISPR-Cas9 Genetic Analysis of Virus-Host Interactions. In: Viruses. Band 10, Nummer 2, 01 2018, S. , doi:10.3390/v10020055, PMID 29385696, PMC 5850362 (freier Volltext).
A. A. Dominguez, W. A. Lim, L. S. Qi: Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation. In: Nature reviews. Molecular cell biology. Band 17, Nummer 1, Januar 2016, S. 5–15, doi:10.1038/nrm.2015.2, PMID 26670017, PMC 4922510 (freier Volltext).
K. Takahashi, S. Yamanaka: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. In: Cell. Band 126, Nummer 4, August 2006, S. 663–676, doi:10.1016/j.cell.2006.07.024, PMID 16904174.
N. A. Kearns, R. M. Genga, M. S. Enuameh, M. Garber, S. A. Wolfe, R. Maehr: Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. In: Development. Band 141, Nummer 1, Januar 2014, S. 219–223, doi:10.1242/dev.103341, PMID 24346702, PMC 3865759 (freier Volltext).
J. Hu, Y. Lei, W. K. Wong, S. Liu, K. C. Lee, X. He, W. You, R. Zhou, J. T. Guo, X. Chen, X. Peng, H. Sun, H. Huang, H. Zhao, B. Feng: Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors. In: Nucleic acids research. Band 42, Nummer 7, April 2014, S. 4375–4390, doi:10.1093/nar/gku109, PMID 24500196, PMC 3985678 (freier Volltext).
M. Kampmann: CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine. In: ACS chemical biology. Band 13, Nummer 2, 02 2018, S. 406–416, doi:10.1021/acschembio.7b00657, PMID 29035510, PMC 5886776 (freier Volltext).
Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJ, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G: Comparison of Cas9 activators in multiple species. In: Nature Methods. 13. Jahrgang, Nr.7, Juli 2016, S.563–567, doi:10.1038/nmeth.3871, PMID 27214048, PMC 4927356 (freier Volltext).
Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, EP, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, Weiss R, Aach J, Collins JJ, Church GM: Highly efficient Cas9-mediated transcriptional programming. In: Nature Methods. 12. Jahrgang, Nr.4, April 2015, S.326–8, doi:10.1038/nmeth.3312, PMID 25730490, PMC 4393883 (freier Volltext).
Zhang Y, Yin C, Zhang T, Li F, Yang W, Kaminski R, Fagan PR, Putatunda R, Young WB, Khalili K, Hu W: CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs. In: Scientific Reports. 5. Jahrgang, Nr.1, November 2015, S.16277, doi:10.1038/srep16277, PMID 26538064, PMC 4633726 (freier Volltext), bibcode:2015NatSR...516277Z.
Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F: Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. In: Nature. 517. Jahrgang, Nr.7536, Januar 2015, S.583–8, doi:10.1038/nature14136, PMID 25494202, PMC 4420636 (freier Volltext), bibcode:2015Natur.517..583K.
L. A. Gilbert, M. A. Horlbeck, B. Adamson, J. E. Villalta, Y. Chen, E. H. Whitehead, C. Guimaraes, B. Panning, H. L. Ploegh, M. C. Bassik, L. S. Qi, M. Kampmann, J. S. Weissman: Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. In: Cell. Band 159, Nummer 3, Oktober 2014, S. 647–661, doi:10.1016/j.cell.2014.09.029, PMID 25307932, PMC 4253859 (freier Volltext).
Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD: A protein-tagging system for signal amplification in gene expression and fluorescence imaging. In: Cell. 159. Jahrgang, Nr.3, Oktober 2014, S.635–46, doi:10.1016/j.cell.2014.09.039, PMID 25307933, PMC 4252608 (freier Volltext).
D. Bikard, W. Jiang, P. Samai, A. Hochschild, F. Zhang, L. A. Marraffini: Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. In: Nucleic acids research. Band 41, Nummer 15, August 2013, S. 7429–7437, doi:10.1093/nar/gkt520, PMID 23761437, PMC 3753641 (freier Volltext).
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Zhang Y, Yin C, Zhang T, Li F, Yang W, Kaminski R, Fagan PR, Putatunda R, Young WB, Khalili K, Hu W: CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs. In: Scientific Reports. 5. Jahrgang, Nr.1, November 2015, S.16277, doi:10.1038/srep16277, PMID 26538064, PMC 4633726 (freier Volltext), bibcode:2015NatSR...516277Z.
Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F: Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. In: Nature. 517. Jahrgang, Nr.7536, Januar 2015, S.583–8, doi:10.1038/nature14136, PMID 25494202, PMC 4420636 (freier Volltext), bibcode:2015Natur.517..583K.
R. Barrangou, C. Fremaux, H. Deveau, M. Richards, P. Boyaval, S. Moineau, D. A. Romero, P. Horvath: CRISPR provides acquired resistance against viruses in prokaryotes. In: Science. Band 315, Nummer 5819, März 2007, S. 1709–1712, doi:10.1126/science.1138140, PMID 17379808.
W. Jiang, D. Bikard, D. Cox, F. Zhang, L. A. Marraffini: RNA-guided editing of bacterial genomes using CRISPR-Cas systems. In: Nature Biotechnology. Band 31, Nummer 3, März 2013, S. 233–239, doi:10.1038/nbt.2508, PMID 23360965, PMC 3748948 (freier Volltext).
D. J. Brocken, M. Tark-Dame, R. T. Dame: dCas9: A Versatile Tool for Epigenome Editing. In: Current issues in molecular biology. Band 26, 2018, S. 15–32, doi:10.21775/cimb.026.015, PMID 28879853.
S. E. Mohr, Y. Hu, B. Ewen-Campen, B. E. Housden, R. Viswanatha, N. Perrimon: CRISPR guide RNA design for research applications. In: The FEBS journal. Band 283, Nummer 17, 09 2016, S. 3232–3238, doi:10.1111/febs.13777, PMID 27276584, PMC 5014588 (freier Volltext).
Maeder ML, Linder SJ, Cascio VM, Fu Y, Ho QH, Joung JK: CRISPR RNA-guided activation of endogenous human genes. In: Nature Methods. 10. Jahrgang, Nr.10, Oktober 2013, S.977–9, doi:10.1038/nmeth.2598, PMID 23892898, PMC 3794058 (freier Volltext).
M. Gebre, J. L. Nomburg, B. E. Gewurz: CRISPR-Cas9 Genetic Analysis of Virus-Host Interactions. In: Viruses. Band 10, Nummer 2, 01 2018, S. , doi:10.3390/v10020055, PMID 29385696, PMC 5850362 (freier Volltext).
A. A. Dominguez, W. A. Lim, L. S. Qi: Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation. In: Nature reviews. Molecular cell biology. Band 17, Nummer 1, Januar 2016, S. 5–15, doi:10.1038/nrm.2015.2, PMID 26670017, PMC 4922510 (freier Volltext).
K. Takahashi, S. Yamanaka: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. In: Cell. Band 126, Nummer 4, August 2006, S. 663–676, doi:10.1016/j.cell.2006.07.024, PMID 16904174.
N. A. Kearns, R. M. Genga, M. S. Enuameh, M. Garber, S. A. Wolfe, R. Maehr: Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells. In: Development. Band 141, Nummer 1, Januar 2014, S. 219–223, doi:10.1242/dev.103341, PMID 24346702, PMC 3865759 (freier Volltext).
J. Hu, Y. Lei, W. K. Wong, S. Liu, K. C. Lee, X. He, W. You, R. Zhou, J. T. Guo, X. Chen, X. Peng, H. Sun, H. Huang, H. Zhao, B. Feng: Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors. In: Nucleic acids research. Band 42, Nummer 7, April 2014, S. 4375–4390, doi:10.1093/nar/gku109, PMID 24500196, PMC 3985678 (freier Volltext).
M. Kampmann: CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine. In: ACS chemical biology. Band 13, Nummer 2, 02 2018, S. 406–416, doi:10.1021/acschembio.7b00657, PMID 29035510, PMC 5886776 (freier Volltext).
Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJ, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G: Comparison of Cas9 activators in multiple species. In: Nature Methods. 13. Jahrgang, Nr.7, Juli 2016, S.563–567, doi:10.1038/nmeth.3871, PMID 27214048, PMC 4927356 (freier Volltext).
Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, EP, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, Weiss R, Aach J, Collins JJ, Church GM: Highly efficient Cas9-mediated transcriptional programming. In: Nature Methods. 12. Jahrgang, Nr.4, April 2015, S.326–8, doi:10.1038/nmeth.3312, PMID 25730490, PMC 4393883 (freier Volltext).
Zhang Y, Yin C, Zhang T, Li F, Yang W, Kaminski R, Fagan PR, Putatunda R, Young WB, Khalili K, Hu W: CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs. In: Scientific Reports. 5. Jahrgang, Nr.1, November 2015, S.16277, doi:10.1038/srep16277, PMID 26538064, PMC 4633726 (freier Volltext), bibcode:2015NatSR...516277Z.
Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F: Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. In: Nature. 517. Jahrgang, Nr.7536, Januar 2015, S.583–8, doi:10.1038/nature14136, PMID 25494202, PMC 4420636 (freier Volltext), bibcode:2015Natur.517..583K.
L. A. Gilbert, M. A. Horlbeck, B. Adamson, J. E. Villalta, Y. Chen, E. H. Whitehead, C. Guimaraes, B. Panning, H. L. Ploegh, M. C. Bassik, L. S. Qi, M. Kampmann, J. S. Weissman: Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. In: Cell. Band 159, Nummer 3, Oktober 2014, S. 647–661, doi:10.1016/j.cell.2014.09.029, PMID 25307932, PMC 4253859 (freier Volltext).
Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD: A protein-tagging system for signal amplification in gene expression and fluorescence imaging. In: Cell. 159. Jahrgang, Nr.3, Oktober 2014, S.635–46, doi:10.1016/j.cell.2014.09.039, PMID 25307933, PMC 4252608 (freier Volltext).
D. Bikard, W. Jiang, P. Samai, A. Hochschild, F. Zhang, L. A. Marraffini: Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. In: Nucleic acids research. Band 41, Nummer 15, August 2013, S. 7429–7437, doi:10.1093/nar/gkt520, PMID 23761437, PMC 3753641 (freier Volltext).