Ele Ferrannini: The Target of Metformin in Type 2 Diabetes. In: New England Journal of Medicine. 2014, Band 371, S. 1547–1548. doi:10.1056/NEJMcibr1409796 Madiraju et al. Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature 2014;510:542–546. doi:10.1038/nature13270
A. Natali, E. Ferrannini: Effects of metformin and thiazolidinediones on suppression of hepatic glucose production and stimulation of glucose uptake in type 2 diabetes: a systematic review. In: Diabetologia. Band 49, Nr. 3, März 2006, S. 434–441, doi:10.1007/s00125-006-0141-7. PMID 16477438. (Review).
Eric Fontaine: Metformin-Induced Mitochondrial Complex I Inhibition: Facts, Uncertainties, and Consequences. In: Frontiers in Endocrinology. Band9, 2018, doi:10.3389/fendo.2018.00753, PMID 30619086, PMC 6304344 (freier Volltext).
Hannah R. Bridges, Andrew J. Y. Jones, Michael N. Pollak, Judy Hirst: Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria. In: Biochemical Journal. Band462, Nr.3, 15. September 2014, S.475–487, doi:10.1042/BJ20140620, PMID 25017630, PMC 4148174 (freier Volltext).
Hannah R. Bridges, James N. Blaza, Zhan Yin, Injae Chung, Michael N. Pollak, Judy Hirst: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. In: Science. Band379, Nr.6630, 27. Januar 2023, S.351–357, doi:10.1126/science.ade3332, PMID 36701435, PMC 7614227 (freier Volltext).
Roman Abrosimov, Marius W. Baeken, Samuel Hauf, Ilka Wittig, Parvana Hajieva, Carmen E. Perrone, Bernd Moosmann: Mitochondrial complex I inhibition triggers NAD+-independent glucose oxidation via successive NADPH formation, “futile” fatty acid cycling, and FADH2 oxidation. In: GeroScience. 25. Januar 2024, doi:10.1007/s11357-023-01059-y.
Bundesärztekammer (BÄK), Kassenärztliche Bundesvereinigung (KBV), Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF): Nationale VersorgungsLeitlinie Typ-2-Diabetes – Teilpublikation der Langfassung, 2. Auflage, Version 1. 2021, doi:10.6101/AZQ/000475 (leitlinien.de [abgerufen am 30. Mai 2022]).
T. Misugi, K. Ozaki u. a.: Insulin-lowering agents inhibit synthesis of testosterone in ovaries of DHEA-induced PCOS rats. In: Gynecologic and obstetric investigation. Band 61, Nr. 4, 2006, S. 208–215, doi:10.1159/000091496. PMID 16479139.
M. S. McDonagh, S. Selph u. a.: Systematic review of the benefits and risks of metformin in treating obesity in children aged 18 years and younger. In: JAMA Pediatrics. Band 168, Nr. 2, Februar 2014, S. 178–184, doi:10.1001/jamapediatrics.2013.4200. PMID 24343296. (Review).
Präoperative Evaluation erwachsener Patienten vor elektiven, nicht herz-thoraxchirurgischen Eingriffen. Gemeinsame Empfehlung der DGAI, DGCH und DGIM. In: Anästhesiologie und Intensivmedizin. Band 58, 2017, S. 349–364, DOI: 10.19224/ai2017.349.
M. Posselt, A. Jaeger, JL. Schaper, M. Radke, JP. Benskin: Determination of polar organic micropollutants in surface and pore water by high-resolution sampling-direct injection-ultra high performance liquid chromatography-tandem mass spectrometry. In: Environmental Sciences Proceedings, Impacts. Band20. Jahrgang, Dezember 2018, S.1716–1727, doi:10.1039/C8EM00390D, PMID 30350841.
Emil Alphonse Werner, James Bell: CCXIV.—The preparation of methylguanidine, and of ββ-dimethylguanidine by the interaction of dicyanodiamide, and methylammonium and dimethylammonium chlorides respectively. In: Journal of the Chemical Society, Transactions. Band121, Nr.0, 1. Januar 1922, S.1790–1794, doi:10.1039/CT9222101790.
H. Mehnert: Diabetologie in Klinik und Praxis. 5. Auflage. Georg Thieme Verlag, 2003, ISBN 3-13-512805-9, S.219ff. (eingeschränkte Vorschau in der Google-Buchsuche).
Bundesärztekammer (BÄK), Kassenärztliche Bundesvereinigung (KBV), Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF): Nationale VersorgungsLeitlinie Typ-2-Diabetes – Teilpublikation der Langfassung, 2. Auflage, Version 1. 2021, doi:10.6101/AZQ/000475 (leitlinien.de [abgerufen am 30. Mai 2022]).
Helena Teede, Marie Misso, Michael Costello et al. im Auftrag des International PCOS Network: International evidence-based guideline for the assessment and management of polycystic ovary syndrome. 2018, ISBN 978-0-646-98332-5 (monash.edu [abgerufen am 30. Mai 2022]).
nih.gov
ncbi.nlm.nih.gov
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. In: The Lancet. Band352. Jahrgang, Nr.9131, 1998, S.854–865, PMID 9742977.
A. Natali, E. Ferrannini: Effects of metformin and thiazolidinediones on suppression of hepatic glucose production and stimulation of glucose uptake in type 2 diabetes: a systematic review. In: Diabetologia. Band 49, Nr. 3, März 2006, S. 434–441, doi:10.1007/s00125-006-0141-7. PMID 16477438. (Review).
Eric Fontaine: Metformin-Induced Mitochondrial Complex I Inhibition: Facts, Uncertainties, and Consequences. In: Frontiers in Endocrinology. Band9, 2018, doi:10.3389/fendo.2018.00753, PMID 30619086, PMC 6304344 (freier Volltext).
Hannah R. Bridges, Andrew J. Y. Jones, Michael N. Pollak, Judy Hirst: Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria. In: Biochemical Journal. Band462, Nr.3, 15. September 2014, S.475–487, doi:10.1042/BJ20140620, PMID 25017630, PMC 4148174 (freier Volltext).
Hannah R. Bridges, James N. Blaza, Zhan Yin, Injae Chung, Michael N. Pollak, Judy Hirst: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. In: Science. Band379, Nr.6630, 27. Januar 2023, S.351–357, doi:10.1126/science.ade3332, PMID 36701435, PMC 7614227 (freier Volltext).
T. Misugi, K. Ozaki u. a.: Insulin-lowering agents inhibit synthesis of testosterone in ovaries of DHEA-induced PCOS rats. In: Gynecologic and obstetric investigation. Band 61, Nr. 4, 2006, S. 208–215, doi:10.1159/000091496. PMID 16479139.
M. S. McDonagh, S. Selph u. a.: Systematic review of the benefits and risks of metformin in treating obesity in children aged 18 years and younger. In: JAMA Pediatrics. Band 168, Nr. 2, Februar 2014, S. 178–184, doi:10.1001/jamapediatrics.2013.4200. PMID 24343296. (Review).
AM. Strugaru, J. Kazakova, E. Butnaru, IC. Caba, Bello-López MÁ, R. Fernández-Torres: Simultaneous determination of metformin and glimepiride in human serum by ultra high performance liquid chromatography quadrupole time of flight mass spectrometry detection. In: Journal of Pharmaceutical and Biomedical Analysis. 20. Februar 2019, Band 20, Nr. 165, S. 276–283, PMID 30572192.
N. Antonopoulos, G. Machairas, G. Migias, A. Vonaparti, V. Brakoulia, C. Pistos, D. Gennimata, I. Panderi: Hydrophilic Interaction Liquid Chromatography-Electrospray Ionization Mass Spectrometry for Therapeutic Drug Monitoring of Metformin and Rosuvastatin in Human Plasma. In: Molecules. 27. Juni 2018, Band 23, Nr. 7, PMID 29954074.
R. Oertel, J. Baldauf, J. Rossmann: Development and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for the quantification of the antidiabetic drug metformin and six others pharmaceuticals in wastewater. In: Journal of Chromatography A. 29. Juni 2018, Band 1556, S. 73–80, PMID 29748091.
C. Hess, M. Unger, B. Madea, B. Stratmann, D. Tschoepe: Range of therapeutic metformin concentrations in clinical blood samples and comparison to a forensic case with death due to lactic acidosis. In: Forensic Science International. Mai 2018, Band 286, S. 106–112, PMID 29574345.
M. Posselt, A. Jaeger, JL. Schaper, M. Radke, JP. Benskin: Determination of polar organic micropollutants in surface and pore water by high-resolution sampling-direct injection-ultra high performance liquid chromatography-tandem mass spectrometry. In: Environmental Sciences Proceedings, Impacts. Band20. Jahrgang, Dezember 2018, S.1716–1727, doi:10.1039/C8EM00390D, PMID 30350841.
Clifford Bailey: Metformin: historical overview. In: Diabetologia. Band 60, 2017, S. 1566–1576, PMID 28776081.