C. G. Roberts, E. Gurisik, T. J. Biden, R. L. Sutherland, A. J. Butt: Synergistic cytotoxicity between tamoxifen and the plant toxin persin in human breast cancer cells is dependent on Bim expression and mediated by modulation of ceramide metabolism. In: Molecular Cancer Therapeutics. 6. Jahrgang, Nr.10, 2007, S.2777–85, doi:10.1158/1535-7163.MCT-07-0374, PMID 17913853 (aacrjournals.org).
doi.org
C. G. Roberts, E. Gurisik, T. J. Biden, R. L. Sutherland, A. J. Butt: Synergistic cytotoxicity between tamoxifen and the plant toxin persin in human breast cancer cells is dependent on Bim expression and mediated by modulation of ceramide metabolism. In: Molecular Cancer Therapeutics. 6. Jahrgang, Nr.10, 2007, S.2777–85, doi:10.1158/1535-7163.MCT-07-0374, PMID 17913853 (aacrjournals.org).
P. B. Oelrichs, J. C. Ng, A. A. Seawright, A. Ward, L. Schäffeler, J. K. MacLeod: Isolation and identification of a compound from avocado (Persea americana) leaves which causes necrosis of the acinar epithelium of the lactating mammary gland and the myocardium. In: Nat. Toxins. 3. Jahrgang, Nr.5, 1995, S.344–9, doi:10.1002/nt.2620030504, PMID 8581318: „non-fatal injury to the lactating mammary gland of the mouse is from 60 to 100 mg/kg. At doses of person above 100 mg/kg, necrosis of myocardial fibres may occur and areas of myocardial fibrosis can be observed in animals surviving for seven days. Hydrothorax and/or pulmonary oedema may be present in more severely affected animals. […] there have been few attempts to investigate the cause of possible toxic effects of the plant in mammals.“
nih.gov
ncbi.nlm.nih.gov
C. G. Roberts, E. Gurisik, T. J. Biden, R. L. Sutherland, A. J. Butt: Synergistic cytotoxicity between tamoxifen and the plant toxin persin in human breast cancer cells is dependent on Bim expression and mediated by modulation of ceramide metabolism. In: Molecular Cancer Therapeutics. 6. Jahrgang, Nr.10, 2007, S.2777–85, doi:10.1158/1535-7163.MCT-07-0374, PMID 17913853 (aacrjournals.org).
P. B. Oelrichs, J. C. Ng, A. A. Seawright, A. Ward, L. Schäffeler, J. K. MacLeod: Isolation and identification of a compound from avocado (Persea americana) leaves which causes necrosis of the acinar epithelium of the lactating mammary gland and the myocardium. In: Nat. Toxins. 3. Jahrgang, Nr.5, 1995, S.344–9, doi:10.1002/nt.2620030504, PMID 8581318: „non-fatal injury to the lactating mammary gland of the mouse is from 60 to 100 mg/kg. At doses of person above 100 mg/kg, necrosis of myocardial fibres may occur and areas of myocardial fibrosis can be observed in animals surviving for seven days. Hydrothorax and/or pulmonary oedema may be present in more severely affected animals. […] there have been few attempts to investigate the cause of possible toxic effects of the plant in mammals.“
