A. R. Pavlov, N. V. Pavlova, S. A. Kozyavkin, A. I. Slesarev: Recent developments in the optimization of thermostable DNA polymerases for efficient applications. In: Trends Biotechnol. Band22, Nr.5, 2004, S.253–260, doi:10.1016/j.tibtech.2004.02.011, PMID 15109812.
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Patentanmeldung EP1752534A1: Hochgeschwindigkeits-PCR unter Verwendung von Hochgeschwindigkeits-DNA-Polymerase. Angemeldet am 12. Mai 2005, veröffentlicht am 14. Februar 2007, Anmelder: Toyo Boseki, Erfinder: Masaya Segawa et Al.
Patentanmeldung US2013034879A1: DNA Polymerases. Angemeldet am 2. August 2012, veröffentlicht am 14. Februar 2007, Anmelder: Fermentas UAB et Al, Erfinder: Remigijus Skirgaila et Al.
Patentanmeldung US2009280539A1: DNA Polymerases and related methods. Angemeldet am 16. April 2009, veröffentlicht am 12. November 2009, Anmelder: Roche Molecular Systems Inc, Erfinder: Keith A. Bauer.
M. Motz, I. Kober, C. Girardot, E. Loeser, U. Bauer, M. Albers, G. Moeckel, E. Minch, H. Voss, C. Kilger, M. Koegl: Elucidation of an archaeal replication protein network to generate enhanced PCR enzymes. In: J Biol Chem. (2002), Band 277(18), S. 16179–88. PMID 11805086. PDF.
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ncbi.nlm.nih.gov
J. Cline, J. C. Braman, H. H. Hogrefe: PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. In: Nucleic Acids Research., Bd. 24, Nr. 18, 1996, S. 3546–3551. PMID 8836181; PMC 146123 (freier Volltext).
B. Villbrandt, H. Sobek, B. Frey, D. Schomburg: Domain exchange: chimeras of Thermus aquaticus DNA polymerase, Escherichia coli DNA polymerase I and Thermotoga neapolitana DNA polymerase. In: Protein Eng., Bd. 13, Nr. 9, 2000, S. 645–654. PMID 11054459.
W. Abu Al-Soud, P. Râdström: Capacity of nine thermostable DNA polymerases to mediate DNA amplification in the presence of PCR-inhibiting samples. In: Appl. Environ. Microbiol., Bd. 64, Nr. 10, 1998, S. 3748–3753. PMID 9758794; PMC 106538 (freier Volltext).
M. Takagi, M. Nishioka, H. Kakihara, M. Kitabayashi, H. Inoue, B. Kawakami, M. Oka, T. Imanaka: Characterization of DNA polymerase from Pyrococcus sp. strain KOD1 and its application to PCR. In: Appl. Environ. Microbiol., Bd. 63, Nr. 11, 1997, S. 4504–4510. PMID 9361436; PMC 168769 (freier Volltext).
H. Kong, R. B. Kucera, W. E. Jack: Characterization of a DNA polymerase from the hyperthermophile archaea Thermococcus litoralis. Vent DNA polymerase, steady state kinetics, thermal stability, processivity, strand displacement, and exonuclease activities. In: J Biol Chem., Bd. 268, Nr. 3, 1993, S. 1965–1975. PMID 8420970.
K. Böhlke, F. M. Pisani, C. E. Vorgias, B. Frey, H. Sobek, M. Rossi, G. Antranikian: PCR performance of the B-type DNA polymerase from the thermophilic euryarchaeon Thermococcus aggregans improved by mutations in the Y-GG/A motif. In: Nucleic Acids Res., Bd. 28, Nr. 20, 2000, S. 3910–3917. PMID 11024170; PMC 110800 (freier Volltext).
K. P. Kim, H. Bae, I. H. Kim, S. T. Kwon: Cloning, expression, and PCR application of DNA polymerase from the hyperthermophilic archaeon, Thermococcus celer. In: Biotechnol Lett. (2011), Bd. 33(2), S. 339–46. PMID 20953664.
Y. Cho, H. S. Lee, Y. J. Kim, S. G. Kang, S. J. Kim, J. H. Lee: Characterization of a dUTPase from the hyperthermophilic archaeon Thermococcus onnurineus NA1 and its application in polymerase chain reaction amplification. In: Mar Biotechnol (NY), Bd. 9, Nr. 4, 2007, S. 450–458. PMID 17549447.
J. I. Lee, Y. J. Kim, H. Bae, S. S. Cho, J. H. Lee, S. T. Kwon: Biochemical properties and PCR performance of a family B DNA polymerase from hyperthermophilic euryarchaeon Thermococcus peptonophilus. In: Appl Biochem Biotechnol., Bd. 160, Nr. 6, 2010, S. 1585–1899. PMID 19440663.
D. Marsic, J. M. Flaman, J. D. Ng: New DNA polymerase from the hyperthermophilic marine archaeon Thermococcus thioreducens. In: Extremophiles, Bd. 12, Nr. 6, 2008, S. 775–788. PMID 18670731.
J. G. Song, E. J. Kil, S. S. Cho, I. H. Kim, S. T. Kwon: An amino acid residue in the middle of the fingers subdomain is involved in Neq DNA polymerase processivity: enhanced processivity of engineered Neq DNA polymerase and its PCR application. In: Protein Eng. Des. Sel., Bd. 23, Nr. 11, 2010, S. 835–842. PMID 20851826.
J. Dietrich, P. Schmitt, M. Zieger, B. Preve, J. L. Rolland, H. Chaabihi, Y. Gueguen: PCR performance of the highly thermostable proof-reading B-type DNA polymerase from Pyrococcus abyssi. In: FEMS Microbiol Lett., Bd. 217, Nr. 1, 2002, S. 89–94. PMID 12445650.
E. M. Kennedy, C. Hergott, S. Dewhurst, B. Kim: The mechanistic architecture of thermostable Pyrococcus furiosus family B DNA polymerase motif A and its interaction with the dNTP substrate. In: Biochemistry (2009), Bd. 48(47), S. 11161–8. PMID 19817489; PMC 3097049 (freier Volltext).
T. Kuroita, H. Matsumura, N. Yokota, M. Kitabayashi, H. Hashimoto, T. Inoue, T. Imanaka, Y. Kai: Structural mechanism for coordination of proofreading and polymerase activities in archaeal DNA polymerases. In: J Mol Biol. (2005), Bd. 351(2), S. 291–8. PMID 16019029.
J. P. McDonald, A. Hall, D. Gasparutto, J. Cadet, J. Ballantyne, R. Woodgate: Novel thermostable Y-family polymerases: applications for the PCR amplification of damaged or ancient DNAs. In: Nucleic Acids Res. (2006), Bd. 34(4), S. 1102–11. PMID 16488882; PMC 1373694 (freier Volltext).
Y. Wang, D. E. Prosen, L. Mei, J. C. Sullivan, M. Finney, P. B. Vander Horn: A novel strategy to engineer DNA polymerases for enhanced processivity and improved performance in vitro. In: Nucleic Acids Res. (2004), Bd. 32(3), S. 1197–207. PMID 14973201; PMC 373405 (freier Volltext).
M. Motz, I. Kober, C. Girardot, E. Loeser, U. Bauer, M. Albers, G. Moeckel, E. Minch, H. Voss, C. Kilger, M. Koegl: Elucidation of an archaeal replication protein network to generate enhanced PCR enzymes. In: J Biol Chem. (2002), Band 277(18), S. 16179–88. PMID 11805086. PDF.
A. R. Pavlov, N. V. Pavlova, S. A. Kozyavkin, A. I. Slesarev: Recent developments in the optimization of thermostable DNA polymerases for efficient applications. In: Trends Biotechnol. Band22, Nr.5, 2004, S.253–260, doi:10.1016/j.tibtech.2004.02.011, PMID 15109812.
W. M. Barnes: PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates. In: Proc Natl Acad Sci U S A (1994), Bd. 91(6), S. 2216–20. PMID 8134376; PMC 43341 (freier Volltext).
W. M. Barnes: The fidelity of Taq polymerase catalyzing PCR is improved by an N-terminal deletion. In: Gene (1992), Band 112(1), S. 29–35. PMID 1551596.
L. S. Merkens, S. K. Bryan, R. E. Moses: Inactivation of the 5'-3' exonuclease of Thermus aquaticus DNA polymerase. In: Biochim Biophys Acta (1995), Band 1264(2), S. 243–8. PMID 7495870.
S. Tabor, C. C. Richardson: A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides. In: Proc Natl Acad Sci U S A., Band 92, Nr. 14, 1995, S. 6339–6343. PMID 7603992; PMC 41513 (freier Volltext).
P. B. Vander Horn, M. C. Davis, J. J. Cunniff, C. Ruan, B. F. McArdle, S. B. Samols, J. Szasz, G. Hu, K. M. Hujer, S. T. Domke, S. R. Brummet, R. B. Moffett, C. W. Fuller: Thermo sequenase DNA polymerase and T. acidophilum pyrophosphatase: new thermostable enzymes for DNA sequencing. In: Biotechniques, Band 22, Nr. 4, 1997, S. 758–762, 764–765. PMID 9105629.
J. M. Prober, G. L. Trainor, R. J. Dam, F. W. Hobbs, C. W. Robertson, R. J. Zagursky, A. J. Cocuzza, M. A. Jensen, K. Baumeister: A system for rapid DNA sequencing with fluorescent chain-terminating dideoxynucleotides. In: Science, Band 238, Nr. 4825, 1987, S. 336–341. PMID 2443975.