J. Boch, H. Scholze, S. Schornack, A. Landgraf, S. Hahn, S. Kay, T. Lahaye, A. Nickstadt, U. Bonas: Breaking the code of DNA binding specificity of TAL-type III effectors. In: Science. Band 326, Nummer 5959, Dezember 2009, ISSN1095-9203, S. 1509–1512, doi:10.1126/science.1178811. PMID 19933107.
Jens Boch: TALEs of genome targeting. In: Nature Biotechnology. 29. Jahrgang, Nr.2, Februar 2011, S.135–6, doi:10.1038/nbt.1767, PMID 21301438.
C. Mussolino, R. Morbitzer, F. Lütge, N. Dannemann, T. Lahaye, T. Cathomen: A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. In: Nucleic acids research. Band 39, Nummer 21, November 2011, S. 9283–9293, ISSN1362-4962. doi:10.1093/nar/gkr597. PMID 21813459. PMC 3241638 (freier Volltext).
M. Christian, T. Cermak, E. L. Doyle, C. Schmidt, F. Zhang, A. Hummel, A. J. Bogdanove, D. F. Voytas: Targeting DNA double-strand breaks with TAL effector nucleases. In: Genetics. Band 186, Nummer 2, Oktober 2010, ISSN1943-2631, S. 757–761, doi:10.1534/genetics.110.120717. PMID 20660643, PMC 2942870 (freier Volltext).
T. Li, S. Huang, W. Z. Jiang, D. Wright, M. H. Spalding, D. P. Weeks, B. Yang: TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain. In: Nucleic acids research. Band 39, Nummer 1, Januar 2011, ISSN1362-4962, S. 359–372, doi:10.1093/nar/gkq704. PMID 20699274, PMC 3017587 (freier Volltext).
T. Cermak, E. L. Doyle, M. Christian, L. Wang, Y. Zhang, C. Schmidt, J. A. Baller, N. V. Somia, A. J. Bogdanove, D. F. Voytas: Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. In: Nucleic acids research. Band 39, Nummer 12, Juli 2011, S. e82, ISSN1362-4962. doi:10.1093/nar/gkr218. PMID 21493687. PMC 3130291 (freier Volltext).
J. C. Miller, S. Tan, G. Qiao, K. A. Barlow, J. Wang, D. F. Xia, X. Meng, D. E. Paschon, E. Leung, S. J. Hinkley, G. P. Dulay, K. L. Hua, I. Ankoudinova, G. J. Cost, F. D. Urnov, H. S. Zhang, M. C. Holmes, L. Zhang, P. D. Gregory, E. J. Rebar: A TALE nuclease architecture for efficient genome editing. In: Nature Biotechnology. Band 29, Nummer 2, Februar 2011, ISSN1546-1696, S. 143–148, doi:10.1038/nbt.1755. PMID 21179091.
D. Hockemeyer, H. Wang, S. Kiani, C. S. Lai, Q. Gao, J. P. Cassady, G. J. Cost, L. Zhang, Y. Santiago, J. C. Miller, B. Zeitler, J. M. Cherone, X. Meng, S. J. Hinkley, E. J. Rebar, P. D. Gregory, F. D. Urnov, R. Jaenisch: Genetic engineering of human pluripotent cells using TALE nucleases. In: Nature Biotechnology. Band 29, Nummer 8, August 2011, S. 731–734, ISSN1546-1696. doi:10.1038/nbt.1927. PMID 21738127. PMC 3152587 (freier Volltext).
A. J. Wood, T. W. Lo, B. Zeitler, C. S. Pickle, E. J. Ralston, A. H. Lee, R. Amora, J. C. Miller, E. Leung, X. Meng, L. Zhang, E. J. Rebar, P. D. Gregory, F. D. Urnov, B. J. Meyer: Targeted genome editing across species using ZFNs and TALENs. In: Science. Band 333, Nummer 6040, Juli 2011, S. 307, ISSN1095-9203. doi:10.1126/science.1207773. PMID 21700836. PMC 3489282 (freier Volltext).
Y. Doyon, T. D. Vo, M. C. Mendel, S. G. Greenberg, J. Wang, D. F. Xia, J. C. Miller, F. D. Urnov, P. D. Gregory, M. C. Holmes: Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures. In: Nature methods. Band 8, Nummer 1, Januar 2011, S. 74–79, ISSN1548-7105. doi:10.1038/nmeth.1539. PMID 21131970.
M. Szczepek, V. Brondani, J. Büchel, L. Serrano, D. J. Segal, T. Cathomen: Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. In: Nature Biotechnology. Band 25, Nummer 7, Juli 2007, S. 786–793, ISSN1087-0156. doi:10.1038/nbt1317. PMID 17603476.
J. Guo, T. Gaj, C. F. Barbas: Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases. In: Journal of molecular biology. Band 400, Nummer 1, Juli 2010, S. 96–107, ISSN1089-8638. doi:10.1016/j.jmb.2010.04.060. PMID 20447404. PMC 2885538 (freier Volltext).
Sara Reardon: Leukaemia success heralds wave of gene-editing therapies. In: Nature. Band527, Nr.7577, 1. November 2015, ISSN1476-4687, S.146–147, doi:10.1038/nature.2015.18737 (nature.com [abgerufen am 12. Juli 2021]).
nature.com
Sara Reardon: Leukaemia success heralds wave of gene-editing therapies. In: Nature. Band527, Nr.7577, 1. November 2015, ISSN1476-4687, S.146–147, doi:10.1038/nature.2015.18737 (nature.com [abgerufen am 12. Juli 2021]).
J. Boch, H. Scholze, S. Schornack, A. Landgraf, S. Hahn, S. Kay, T. Lahaye, A. Nickstadt, U. Bonas: Breaking the code of DNA binding specificity of TAL-type III effectors. In: Science. Band 326, Nummer 5959, Dezember 2009, ISSN1095-9203, S. 1509–1512, doi:10.1126/science.1178811. PMID 19933107.
Jens Boch: TALEs of genome targeting. In: Nature Biotechnology. 29. Jahrgang, Nr.2, Februar 2011, S.135–6, doi:10.1038/nbt.1767, PMID 21301438.
C. Mussolino, R. Morbitzer, F. Lütge, N. Dannemann, T. Lahaye, T. Cathomen: A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. In: Nucleic acids research. Band 39, Nummer 21, November 2011, S. 9283–9293, ISSN1362-4962. doi:10.1093/nar/gkr597. PMID 21813459. PMC 3241638 (freier Volltext).
M. Christian, T. Cermak, E. L. Doyle, C. Schmidt, F. Zhang, A. Hummel, A. J. Bogdanove, D. F. Voytas: Targeting DNA double-strand breaks with TAL effector nucleases. In: Genetics. Band 186, Nummer 2, Oktober 2010, ISSN1943-2631, S. 757–761, doi:10.1534/genetics.110.120717. PMID 20660643, PMC 2942870 (freier Volltext).
T. Li, S. Huang, W. Z. Jiang, D. Wright, M. H. Spalding, D. P. Weeks, B. Yang: TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain. In: Nucleic acids research. Band 39, Nummer 1, Januar 2011, ISSN1362-4962, S. 359–372, doi:10.1093/nar/gkq704. PMID 20699274, PMC 3017587 (freier Volltext).
T. Cermak, E. L. Doyle, M. Christian, L. Wang, Y. Zhang, C. Schmidt, J. A. Baller, N. V. Somia, A. J. Bogdanove, D. F. Voytas: Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. In: Nucleic acids research. Band 39, Nummer 12, Juli 2011, S. e82, ISSN1362-4962. doi:10.1093/nar/gkr218. PMID 21493687. PMC 3130291 (freier Volltext).
J. C. Miller, S. Tan, G. Qiao, K. A. Barlow, J. Wang, D. F. Xia, X. Meng, D. E. Paschon, E. Leung, S. J. Hinkley, G. P. Dulay, K. L. Hua, I. Ankoudinova, G. J. Cost, F. D. Urnov, H. S. Zhang, M. C. Holmes, L. Zhang, P. D. Gregory, E. J. Rebar: A TALE nuclease architecture for efficient genome editing. In: Nature Biotechnology. Band 29, Nummer 2, Februar 2011, ISSN1546-1696, S. 143–148, doi:10.1038/nbt.1755. PMID 21179091.
D. Hockemeyer, H. Wang, S. Kiani, C. S. Lai, Q. Gao, J. P. Cassady, G. J. Cost, L. Zhang, Y. Santiago, J. C. Miller, B. Zeitler, J. M. Cherone, X. Meng, S. J. Hinkley, E. J. Rebar, P. D. Gregory, F. D. Urnov, R. Jaenisch: Genetic engineering of human pluripotent cells using TALE nucleases. In: Nature Biotechnology. Band 29, Nummer 8, August 2011, S. 731–734, ISSN1546-1696. doi:10.1038/nbt.1927. PMID 21738127. PMC 3152587 (freier Volltext).
A. J. Wood, T. W. Lo, B. Zeitler, C. S. Pickle, E. J. Ralston, A. H. Lee, R. Amora, J. C. Miller, E. Leung, X. Meng, L. Zhang, E. J. Rebar, P. D. Gregory, F. D. Urnov, B. J. Meyer: Targeted genome editing across species using ZFNs and TALENs. In: Science. Band 333, Nummer 6040, Juli 2011, S. 307, ISSN1095-9203. doi:10.1126/science.1207773. PMID 21700836. PMC 3489282 (freier Volltext).
Y. Doyon, T. D. Vo, M. C. Mendel, S. G. Greenberg, J. Wang, D. F. Xia, J. C. Miller, F. D. Urnov, P. D. Gregory, M. C. Holmes: Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures. In: Nature methods. Band 8, Nummer 1, Januar 2011, S. 74–79, ISSN1548-7105. doi:10.1038/nmeth.1539. PMID 21131970.
M. Szczepek, V. Brondani, J. Büchel, L. Serrano, D. J. Segal, T. Cathomen: Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. In: Nature Biotechnology. Band 25, Nummer 7, Juli 2007, S. 786–793, ISSN1087-0156. doi:10.1038/nbt1317. PMID 17603476.
J. Guo, T. Gaj, C. F. Barbas: Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases. In: Journal of molecular biology. Band 400, Nummer 1, Juli 2010, S. 96–107, ISSN1089-8638. doi:10.1016/j.jmb.2010.04.060. PMID 20447404. PMC 2885538 (freier Volltext).
zdb-katalog.de
J. Boch, H. Scholze, S. Schornack, A. Landgraf, S. Hahn, S. Kay, T. Lahaye, A. Nickstadt, U. Bonas: Breaking the code of DNA binding specificity of TAL-type III effectors. In: Science. Band 326, Nummer 5959, Dezember 2009, ISSN1095-9203, S. 1509–1512, doi:10.1126/science.1178811. PMID 19933107.
C. Mussolino, R. Morbitzer, F. Lütge, N. Dannemann, T. Lahaye, T. Cathomen: A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. In: Nucleic acids research. Band 39, Nummer 21, November 2011, S. 9283–9293, ISSN1362-4962. doi:10.1093/nar/gkr597. PMID 21813459. PMC 3241638 (freier Volltext).
M. Christian, T. Cermak, E. L. Doyle, C. Schmidt, F. Zhang, A. Hummel, A. J. Bogdanove, D. F. Voytas: Targeting DNA double-strand breaks with TAL effector nucleases. In: Genetics. Band 186, Nummer 2, Oktober 2010, ISSN1943-2631, S. 757–761, doi:10.1534/genetics.110.120717. PMID 20660643, PMC 2942870 (freier Volltext).
T. Li, S. Huang, W. Z. Jiang, D. Wright, M. H. Spalding, D. P. Weeks, B. Yang: TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain. In: Nucleic acids research. Band 39, Nummer 1, Januar 2011, ISSN1362-4962, S. 359–372, doi:10.1093/nar/gkq704. PMID 20699274, PMC 3017587 (freier Volltext).
T. Cermak, E. L. Doyle, M. Christian, L. Wang, Y. Zhang, C. Schmidt, J. A. Baller, N. V. Somia, A. J. Bogdanove, D. F. Voytas: Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. In: Nucleic acids research. Band 39, Nummer 12, Juli 2011, S. e82, ISSN1362-4962. doi:10.1093/nar/gkr218. PMID 21493687. PMC 3130291 (freier Volltext).
J. C. Miller, S. Tan, G. Qiao, K. A. Barlow, J. Wang, D. F. Xia, X. Meng, D. E. Paschon, E. Leung, S. J. Hinkley, G. P. Dulay, K. L. Hua, I. Ankoudinova, G. J. Cost, F. D. Urnov, H. S. Zhang, M. C. Holmes, L. Zhang, P. D. Gregory, E. J. Rebar: A TALE nuclease architecture for efficient genome editing. In: Nature Biotechnology. Band 29, Nummer 2, Februar 2011, ISSN1546-1696, S. 143–148, doi:10.1038/nbt.1755. PMID 21179091.
D. Hockemeyer, H. Wang, S. Kiani, C. S. Lai, Q. Gao, J. P. Cassady, G. J. Cost, L. Zhang, Y. Santiago, J. C. Miller, B. Zeitler, J. M. Cherone, X. Meng, S. J. Hinkley, E. J. Rebar, P. D. Gregory, F. D. Urnov, R. Jaenisch: Genetic engineering of human pluripotent cells using TALE nucleases. In: Nature Biotechnology. Band 29, Nummer 8, August 2011, S. 731–734, ISSN1546-1696. doi:10.1038/nbt.1927. PMID 21738127. PMC 3152587 (freier Volltext).
A. J. Wood, T. W. Lo, B. Zeitler, C. S. Pickle, E. J. Ralston, A. H. Lee, R. Amora, J. C. Miller, E. Leung, X. Meng, L. Zhang, E. J. Rebar, P. D. Gregory, F. D. Urnov, B. J. Meyer: Targeted genome editing across species using ZFNs and TALENs. In: Science. Band 333, Nummer 6040, Juli 2011, S. 307, ISSN1095-9203. doi:10.1126/science.1207773. PMID 21700836. PMC 3489282 (freier Volltext).
Y. Doyon, T. D. Vo, M. C. Mendel, S. G. Greenberg, J. Wang, D. F. Xia, J. C. Miller, F. D. Urnov, P. D. Gregory, M. C. Holmes: Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures. In: Nature methods. Band 8, Nummer 1, Januar 2011, S. 74–79, ISSN1548-7105. doi:10.1038/nmeth.1539. PMID 21131970.
M. Szczepek, V. Brondani, J. Büchel, L. Serrano, D. J. Segal, T. Cathomen: Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. In: Nature Biotechnology. Band 25, Nummer 7, Juli 2007, S. 786–793, ISSN1087-0156. doi:10.1038/nbt1317. PMID 17603476.
J. Guo, T. Gaj, C. F. Barbas: Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases. In: Journal of molecular biology. Band 400, Nummer 1, Juli 2010, S. 96–107, ISSN1089-8638. doi:10.1016/j.jmb.2010.04.060. PMID 20447404. PMC 2885538 (freier Volltext).
Sara Reardon: Leukaemia success heralds wave of gene-editing therapies. In: Nature. Band527, Nr.7577, 1. November 2015, ISSN1476-4687, S.146–147, doi:10.1038/nature.2015.18737 (nature.com [abgerufen am 12. Juli 2021]).