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R. Keyhanmanesh, S. Saadat, M. Mohammadi, A. A. Shahbazfar, M. Fallahi: The Protective Effect of α-Hederin, the Active Constituent of Nigella sativa, on Lung Inflammation and Blood Cytokines in Ovalbumin Sensitized Guinea Pigs. In: Phytotherapy Research. Band 29, Nummer 11, November 2015, S. 1761–1767, doi:10.1002/ptr.5429, PMID 26292851.
S. Saadat, M. Mohammadi, M. Fallahi, R. Keyhanmanesh, M. R. Aslani: The protective effect of α-hederin, the active constituent of Nigella sativa, on tracheal responsiveness and lung inflammation in ovalbumin-sensitized guinea pigs. In: The Journal of Physiological Sciences. Band 65, Nummer 3, Mai 2015, S. 285–292, doi:10.1007/s12576-015-0367-6, PMID 25752254.
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A. Sieben, L. Prenner, T. Sorkalla, A. Wolf, D. Jakobs, F. Runkel, H. Häberlein: Alpha-hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors. In: Biochemistry. Band 48, Nummer 15, April 2009, S. 3477–3482, doi:10.1021/bi802036b, PMID 19278262.
A. Trute, J. Gross, E. Mutschler, A. Nahrstedt: In vitro antispasmodic compounds of the dry extract obtained from Hedera helix. In: Planta medica. Band 63, Nummer 2, April 1997, S. 125–129, doi:10.1055/s-2006-957627, PMID 9140224.
A. Wolf, R. Gosens, H. Meurs, H. Häberlein: Pre-treatment with α-hederin increases β-adrenoceptor mediated relaxation of airway smooth muscle. In: Phytomedicine : international journal of phytotherapy and phytopharmacology. Band 18, Nummer 2–3, Januar 2011, S. 214–218, doi:10.1016/j.phymed.2010.05.010, PMID 20637581.
T. A. Prescott, L. P. Rigby, N. C. Veitch, M. S. Simmonds: The haploinsufficiency profile of α-hederin suggests a caspofungin-like antifungal mode of action. In: Phytochemistry. Band 101, Mai 2014, S. 116–120, doi:10.1016/j.phytochem.2014.01.022, PMID 24569176.
M. A. Randhawa, M. S. Alghamdi: Anticancer activity of Nigella sativa (black seed) - a review. In: The American Journal of Chinese Medicine. Band 39, Nummer 6, 2011, S. 1075–1091, doi:10.1142/S0192415X1100941X, PMID 22083982.
J. H. Lorent, C. Léonard, M. Abouzi, F. Akabi, J. Quetin-Leclercq, M. P. Mingeot-Leclercq: α-Hederin Induces Apoptosis, Membrane Permeabilization and Morphologic Changes in Two Cancer Cell Lines Through a Cholesterol-Dependent Mechanism. In: Planta medica. Band 82, Nummer 18, Dezember 2016, S. 1532–1539, doi:10.1055/s-0042-114780, PMID 27574896.
F. Delmas, C. Di Giorgio, R. Elias, M. Gasquet, N. Azas, V. Mshvildadze, G. Dekanosidze, E. Kemertelidze, P. Timon-David: Antileishmanial activity of three saponins isolated from ivy, alpha-hederin, beta-hederin and hederacolchiside A1, as compared to their action on mammalian cells cultured in vitro. In: Planta medica. Band 66, Nummer 4, Mai 2000, S. 343–347, doi:10.1055/s-2000-8541, PMID 10865451.
J. Schulte-Michels, A. Wolf, S. Aatz, K. Engelhard, A. Sieben, M. Martinez-Osuna, F. Häberlein, H. Häberlein: α-Hederin inhibits G protein-coupled receptor kinase 2-mediated phosphorylation of β2-adrenergic receptors. In: Phytomedicine : international journal of phytotherapy and phytopharmacology. Band 23, Nummer 1, Januar 2016, S. 52–57, doi:10.1016/j.phymed.2015.12.001, PMID 26902407.
K. Wojciechowski, M. Orczyk, T. Gutberlet, T. Geue: Complexation of phospholipids and cholesterol by triterpenic saponins in bulk and in monolayers. In: Biochimica et Biophysica Acta. Band 1858, Nummer 2, Februar 2016, S. 363–373, doi:10.1016/j.bbamem.2015.12.001, PMID 26654784.
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R. Keyhanmanesh, S. Saadat, M. Mohammadi, A. A. Shahbazfar, M. Fallahi: The Protective Effect of α-Hederin, the Active Constituent of Nigella sativa, on Lung Inflammation and Blood Cytokines in Ovalbumin Sensitized Guinea Pigs. In: Phytotherapy Research. Band 29, Nummer 11, November 2015, S. 1761–1767, doi:10.1002/ptr.5429, PMID 26292851.
M. Fallahi, R. Keyhanmanesh, A. M. Khamaneh, M. A. Ebrahimi Saadatlou, S. Saadat, H. Ebrahimi: Effect of Alpha-Hederin, the active constituent of Nigella sativa, on miRNA-126, IL-13 mRNA levels and inflammation of lungs in ovalbumin-sensitized male rats. In: Avicenna journal of phytomedicine. Band 6, Nummer 1, 2016 Jan-Feb, S. 77–85, PMID 27247924, PMC 4884220 (freier Volltext).
J. Schulte-Michels, F. Runkel, S. Gokorsch, H. Häberlein: Ivy leaves dry extract EA 575® decreases LPS-induced IL-6 release from murine macrophages. In: Die Pharmazie. Band 71, Nummer 3, März 2016, S. 158–161, PMID 27183712.
Y. K. Kim, R. G. Kim, S. J. Park, J. H. Ha, J. W. Choi, H. J. Park, K. T. Lee: In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells. In: Biological & Pharmaceutical Bulletin. Band 25, Nummer 4, April 2002, S. 472–476, PMID 11995927.
S. Saadat, M. Mohammadi, M. Fallahi, R. Keyhanmanesh, M. R. Aslani: The protective effect of α-hederin, the active constituent of Nigella sativa, on tracheal responsiveness and lung inflammation in ovalbumin-sensitized guinea pigs. In: The Journal of Physiological Sciences. Band 65, Nummer 3, Mai 2015, S. 285–292, doi:10.1007/s12576-015-0367-6, PMID 25752254.
M. Mendel, M. Chłopecka, N. Dziekan, W. Karlik, M. Wiechetek: Participation of extracellular calcium in α-hederin-induced contractions of rat isolated stomach strips. In: Journal of Ethnopharmacology. Band 146, Nummer 1, März 2013, S. 423–426, doi:10.1016/j.jep.2012.12.023, PMID 23274745.
A. Sieben, L. Prenner, T. Sorkalla, A. Wolf, D. Jakobs, F. Runkel, H. Häberlein: Alpha-hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors. In: Biochemistry. Band 48, Nummer 15, April 2009, S. 3477–3482, doi:10.1021/bi802036b, PMID 19278262.
A. Trute, J. Gross, E. Mutschler, A. Nahrstedt: In vitro antispasmodic compounds of the dry extract obtained from Hedera helix. In: Planta medica. Band 63, Nummer 2, April 1997, S. 125–129, doi:10.1055/s-2006-957627, PMID 9140224.
A. Wolf, R. Gosens, H. Meurs, H. Häberlein: Pre-treatment with α-hederin increases β-adrenoceptor mediated relaxation of airway smooth muscle. In: Phytomedicine : international journal of phytotherapy and phytopharmacology. Band 18, Nummer 2–3, Januar 2011, S. 214–218, doi:10.1016/j.phymed.2010.05.010, PMID 20637581.
I. Gülçin, V. Mshvildadze, A. Gepdiremen, R. Elias: Antioxidant activity of saponins isolated from ivy: alpha-hederin, hederasaponin-C, hederacolchiside-E and hederacolchiside-F. In: Planta medica. Band 70, Nummer 6, Juni 2004, S. 561–563, PMID 15241892.
T. A. Prescott, L. P. Rigby, N. C. Veitch, M. S. Simmonds: The haploinsufficiency profile of α-hederin suggests a caspofungin-like antifungal mode of action. In: Phytochemistry. Band 101, Mai 2014, S. 116–120, doi:10.1016/j.phytochem.2014.01.022, PMID 24569176.
M. A. Randhawa, M. S. Alghamdi: Anticancer activity of Nigella sativa (black seed) - a review. In: The American Journal of Chinese Medicine. Band 39, Nummer 6, 2011, S. 1075–1091, doi:10.1142/S0192415X1100941X, PMID 22083982.
J. H. Lorent, C. Léonard, M. Abouzi, F. Akabi, J. Quetin-Leclercq, M. P. Mingeot-Leclercq: α-Hederin Induces Apoptosis, Membrane Permeabilization and Morphologic Changes in Two Cancer Cell Lines Through a Cholesterol-Dependent Mechanism. In: Planta medica. Band 82, Nummer 18, Dezember 2016, S. 1532–1539, doi:10.1055/s-0042-114780, PMID 27574896.
F. Delmas, C. Di Giorgio, R. Elias, M. Gasquet, N. Azas, V. Mshvildadze, G. Dekanosidze, E. Kemertelidze, P. Timon-David: Antileishmanial activity of three saponins isolated from ivy, alpha-hederin, beta-hederin and hederacolchiside A1, as compared to their action on mammalian cells cultured in vitro. In: Planta medica. Band 66, Nummer 4, Mai 2000, S. 343–347, doi:10.1055/s-2000-8541, PMID 10865451.
J. Schulte-Michels, A. Wolf, S. Aatz, K. Engelhard, A. Sieben, M. Martinez-Osuna, F. Häberlein, H. Häberlein: α-Hederin inhibits G protein-coupled receptor kinase 2-mediated phosphorylation of β2-adrenergic receptors. In: Phytomedicine : international journal of phytotherapy and phytopharmacology. Band 23, Nummer 1, Januar 2016, S. 52–57, doi:10.1016/j.phymed.2015.12.001, PMID 26902407.
K. Wojciechowski, M. Orczyk, T. Gutberlet, T. Geue: Complexation of phospholipids and cholesterol by triterpenic saponins in bulk and in monolayers. In: Biochimica et Biophysica Acta. Band 1858, Nummer 2, Februar 2016, S. 363–373, doi:10.1016/j.bbamem.2015.12.001, PMID 26654784.
