Βάλσαμο (Greek Wikipedia)

Analysis of information sources in references of the Wikipedia article "Βάλσαμο" in Greek language version.

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«Pharmacokinetics of tea catechins after ingestion of green tea and (−)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability» (PDF). Cancer Epidemiol. Biomarkers Prev. 11 (10 Pt 1): 1025–1032. 2002. PMID 12376503. http://cebp.aacrjournals.org/content/11/10/1025.full.pdf.

acdlabs.com

«Αρχειοθετημένο αντίγραφο». Αρχειοθετήθηκε από το πρωτότυπο στις 9 Μαρτίου 2016. Ανακτήθηκε στις 18 Φεβρουαρίου 2016.

altmedrev.com

Kelly, GS (June 2011). «Quercetin» (PDF). Alternative Medicine Review 16 (2): 172–194. ISSN 10895159. Αρχειοθετήθηκε από το πρωτότυπο στις 2016-12-13. https://web.archive.org/web/20161213071215/http://www.altmedrev.com/publications/16/2/172.pdf. Ανακτήθηκε στις 2016-02-18.

archive.org

Beentje, Henk (2010). The Kew Plant Glossary. Richmond, Surrey: Royal Botanic Gardens, Kew. ISBN 978-1-84246-422-9. , p. 106
«Adverse effects profile of the herbal antidepressant St. John's wort (Hypericum perforatum L.)». Eur. J. Clin. Pharmacol. 54 (8): 589–94. 1998. doi:10.1007/s002280050519. PMID 9860144. https://archive.org/details/sim_european-journal-of-clinical-pharmacology_1998-10_54_8/page/589.
«Adverse reactions to St John's Wort». Can J Psychiatry 46 (1): 77–9. 2001. PMID 11221494. https://archive.org/details/sim_canadian-journal-of-psychiatry_2001-02_46_1/page/77.
Greeson, JM; Sanford, B; Monti, DA (Feb 2001). «St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature.». Psychopharmacology (Berl) 153 (4): 402–14. doi:10.1007/s002130000625. PMID 11243487. https://archive.org/details/sim_psychopharmacology_2001-02_153_4/page/402.
Tirona, RG; Bailey, DG (June 2006). «Herbal product-drug interactions mediated by induction.». British Journal of Clinical Pharmacology 61 (6): 677–81. doi:10.1111/j.1365-2125.2006.02684.x. PMID 16722828. https://archive.org/details/sim_british-journal-of-clinical-pharmacology_2006-06_61_6/page/677.

benthamscience.com

«Hypericin--the facts about a controversial agent» (PDF). Curr. Pharm. Des. 11 (2): 233–253. 2005. doi:10.2174/1381612053382287. PMID 15638760. Αρχειοθετήθηκε από το πρωτότυπο στις 2013-10-05. https://web.archive.org/web/20131005011912/http://www.benthamscience.com/cpd/sample/cpd11-2/0007B.pdf. Ανακτήθηκε στις 2016-02-18.

books.google.com

John L. Harper (2010). Population Biology of Plants. Blackburn Press. ISBN 978-1-932846-24-9.

bsbi.org.uk

«BSBI List 2007». Botanical Society of Britain and Ireland. Αρχειοθετήθηκε από το πρωτότυπο (xls) στις 25 Ιανουαρίου 2015. Ανακτήθηκε στις 17 Οκτωβρίου 2014.

collinsdictionary.com

«Collins dictionary».

doi.org

dx.doi.org

«Topical application of St. John's wort (Hypericum perforatum)». Planta Med. 80 (2-3): 109–20. 2014. doi:10.1055/s-0033-1351019. PMID 24214835. «Anti-inflammatory mechanisms of hyperforin have been described as inhibition of cyclooxygenase-1 (but not COX-2) and 5-lipoxygenase at low concentrations of 0.3 µmol/L and 1.2 µmol/L, respectively [52], and of PGE2 production in vitro [53] and in vivo with superior efficiency (ED50 = 1 mg/kg) compared to indomethacin (5 mg/kg) [54]. Hyperforin turned out to be a novel type of 5-lipoxygenase inhibitor with high effectivity in vivo [55] and suppressed oxidative bursts in polymorphonuclear cells at 1.8 µmol/L in vitro [56]. Inhibition of IFN-γ production, strong downregulation of CXCR3 expression on activated T cells, and downregulation of matrix metalloproteinase 9 expression caused Cabrelle et al. [57] to test the effectivity of hyperforin in a rat model of experimental allergic encephalomyelitis (EAE). Hyperforin attenuated the symptoms significantly, and the authors discussed hyperforin as a putative therapeutic molecule for the treatment of autoimmune inflammatory diseases sustained by Th1 cells.».
Zobayed SMA, Afreen F, Goto E, Kozai T (2006). «Plant–Environment Interactions: Accumulation of Hypericin in Dark Glands of Hypericum perforatum». Annals of Botany 98 (4): 793–804. doi:10.1093/aob/mcl169.
«Hypericum perforatum (St John's Wort): a non-selective reuptake inhibitor? A review of the recent advances in its pharmacology». J. Psychopharmacol. (Oxford) 15 (1): 47–54. 2001. doi:10.1177/026988110101500109. PMID 11277608.
«Efficacy and acceptability of pharmacological treatments for depressive disorders in primary care: systematic review and network meta-analysis». Ann Fam Med 13 (1): 69–79. February 2015. doi:10.1370/afm.1687. PMID 25583895. «In network meta-analysis, tricyclic and tetracyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), a serotonin-noradrenaline reuptake inhibitor (SNRI; venlafaxine), a low-dose serotonin antagonist and reuptake inhibitor (SARI; trazodone) and hypericum extracts were found to be significantly superior to placebo, with estimated odds ratios between 1.69 and 2.03. There were no statistically significant differences between these drug classes. Reversible inhibitors of monoaminoxidase A (rMAO-As) and hypericum extracts were associated with significantly fewer dropouts because of adverse effects compared with TCAs, SSRIs, the SNRI, a noradrenaline reuptake inhibitor (NRI), and noradrenergic and specific serotonergic antidepressant agents (NaSSAs). ... TCAs and SSRIs have the most solid evidence base. Further agents (hypericum, rMAO-As, SNRI, NRI, NaSSAs, SARI) showed some positive results, but limitations of the currently available evidence makes a clear recommendation on their place in clinical practice difficult.».
Linde, Klaus, επιμ. (2008). «St John's wort for major depression». Cochrane Database Syst Rev (4): CD000448. doi:10.1002/14651858.CD000448.pub3. PMID 18843608.
Dörks, M; Langner, I; Dittmann, U; Timmer, A; Garbe, E (August 2013). «Antidepressant drug use and off-label prescribing in children and adolescents in Germany: results from a large population-based cohort study.». European child & adolescent psychiatry 22 (8): 511–8. doi:10.1007/s00787-013-0395-9. PMID 23455627.
«Antidepressant use in children and adolescents in Germany». J Child Adolesc Psychopharmacol 16 (1-2): 197–206. February–April 2006. doi:10.1089/cap.2006.16.197. PMID 16553540.
Butterweck, Veronika; Schmidt, Mathias (2007-07-01). «St. John's wort: Role of active compounds for its mechanism of action and efficacy» (στα αγγλικά). Wiener Medizinische Wochenschrift 157 (13-14): 356–361. doi:10.1007/s10354-007-0440-8. ISSN 0043-5341. http://link.springer.com/article/10.1007/s10354-007-0440-8.
«Adverse effects profile of the herbal antidepressant St. John's wort (Hypericum perforatum L.)». Eur. J. Clin. Pharmacol. 54 (8): 589–94. 1998. doi:10.1007/s002280050519. PMID 9860144. https://archive.org/details/sim_european-journal-of-clinical-pharmacology_1998-10_54_8/page/589.
Greeson, JM; Sanford, B; Monti, DA (Feb 2001). «St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature.». Psychopharmacology (Berl) 153 (4): 402–14. doi:10.1007/s002130000625. PMID 11243487. https://archive.org/details/sim_psychopharmacology_2001-02_153_4/page/402.
Hoban, Claire L.; Byard, Roger W.; Musgrave, Ian F. (Jul 2015). «A comparison of patterns of spontaneous adverse drug reaction reporting with St. John's Wort and fluoxetine during the period 2000-2013». Clinical and Experimental Pharmacology and Physiology 42: 747–51. doi:10.1111/1440-1681.12424. PMID 25988866. http://onlinelibrary.wiley.com/doi/10.1111/1440-1681.12424/abstract. Ανακτήθηκε στις 7 June 2015. «The organ systems affected by ADRs to St John's Wort and fluoxetine have a similar profile, with the majority of cases affecting the central nervous system (45.2%, 61.7%).».
«Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and females» (PDF). Br J Clin Pharmacol 57 (4): 495–499. 2004. doi:10.1111/j.1365-2125.2003.02049.x. PMID 15025748. PMC 1884478. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884478/pdf/bcp0057-0495.pdf.
«Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics». Mol Nutr Food Res 52 (7): 772–9. 2008. doi:10.1002/mnfr.200700081. PMID 18214850.
Russo, Emilio; Scicchitano, Francesca; Whalley, Benjamin J.; Mazzitello, Carmela; Ciriaco, Miriam; Esposito, Stefania; Patanè, Marinella; Upton, Roy και άλλοι. (May 2014). «Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions.». Phytotherapy Research 28 (5): 643–655. doi:10.1002/ptr.5050. PMID 23897801.
Tirona, RG; Bailey, DG (June 2006). «Herbal product-drug interactions mediated by induction.». British Journal of Clinical Pharmacology 61 (6): 677–81. doi:10.1111/j.1365-2125.2006.02684.x. PMID 16722828. https://archive.org/details/sim_british-journal-of-clinical-pharmacology_2006-06_61_6/page/677.
Borrelli, F; Izzo, AA (December 2009). «Herb-drug interactions with St John's wort (Hypericum perforatum): an update on clinical observations.». The AAPS journal 11 (4): 710–27. doi:10.1208/s12248-009-9146-8. PMID 19859815.
«Biologically active and other chemical constituents of the herb of Hypericum perforatum L». Pharmacopsychiatry 30 Suppl 2 (Suppl 2): 129–34. 1997. doi:10.1055/s-2007-979533. PMID 9342774.
«Mechanism of action of St John's wort in depression : what is known?». CNS Drugs 17 (8): 539–62. 2003. doi:10.2165/00023210-200317080-00001. PMID 12775192. http://link.springer.com/content/pdf/10.2165/00023210-200317080-00001.pdf.
«Current St John's wort research from mode of action to clinical efficacy». Pharmacol. Res. 47 (2): 101–9. 2003. doi:10.1016/S1043-6618(02)00266-9. PMID 12543057. http://linkinghub.elsevier.com/retrieve/pii/S1043661802002669.
«St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature» (PDF). Psychopharmacology (Berl.) 153 (4): 402–414. February 2001. doi:10.1007/s002130000625. PMID 11243487. Αρχειοθετήθηκε από το πρωτότυπο στις 2014-06-11. https://web.archive.org/web/20140611050347/http://sites.duke.edu/greesonlab/files/2011/07/Greeson_etal_2001_Psychopharm-St.-Johns-Wort.pdf. Ανακτήθηκε στις 2016-02-18.
«Adhyperforin as a contributor to the effect of Hypericum perforatum L. in biochemical models of antidepressant activity». Life Sci. 68 (14): 1593–1605. 2001. doi:10.1016/S0024-3205(01)00946-8. PMID 11263672.
«St. John's wort and its constituent hyperforin concordantly regulate expression of genes encoding enzymes involved in basic cellular pathways». Pharmacogenet. Genomics 15 (11): 817–829. 2005. doi:10.1097/01.fpc.0000175597.60066.3d. PMID 16220113.
«Hypericin--the facts about a controversial agent» (PDF). Curr. Pharm. Des. 11 (2): 233–253. 2005. doi:10.2174/1381612053382287. PMID 15638760. Αρχειοθετήθηκε από το πρωτότυπο στις 2013-10-05. https://web.archive.org/web/20131005011912/http://www.benthamscience.com/cpd/sample/cpd11-2/0007B.pdf. Ανακτήθηκε στις 2016-02-18.
«Catalytic inhibition of human DNA topoisomerase IIalpha by hypericin, a naphthodianthrone from St. John's wort (Hypericum perforatum)». Biochem. Pharmacol. 62 (8): 1059–1070. 2001. doi:10.1016/S0006-2952(01)00759-6. PMID 11597574.
«Therapeutic agents with dramatic antiretroviral activity and little toxicity at effective doses: aromatic polycyclic diones hypericin and pseudohypericin» (PDF). Proc. Natl. Acad. Sci. U.S.A. 85 (14): 5230–5234. 1988. doi:10.1073/pnas.85.14.5230. PMID 2839837. PMC 281723. http://www.pnas.org/content/85/14/5230.full.pdf.
«Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin» (PDF). Proc. Natl. Acad. Sci. U.S.A. 86 (15): 5963–5967. 1989. doi:10.1073/pnas.86.15.5963. PMID 2548193. PMC 297751. http://www.pnas.org/content/86/15/5963.full.pdf.
«Hypericin and pseudohypericin specifically inhibit protein kinase C: possible relation to their antiretroviral activity». Biochem. Biophys. Res. Commun. 165 (3): December 1989. 1989. doi:10.1016/0006-291X(89)92730-7. PMID 2558652.
«Inhibition of human cytochromes P450 by components of Ginkgo biloba». J. Pharm. Pharmacol. 56 (8): 1039–1044. 2004. doi:10.1211/0022357044021. PMID 15285849.
«Fatty acid synthase inhibition by amentoflavone induces apoptosis and antiproliferation in human breast cancer cells» (PDF). Biol. Pharm. Bull. 32 (8): 1427–1432. 2009. doi:10.1248/bpb.32.1427. PMID 19652385. https://www.jstage.jst.go.jp/article/bpb/32/8/32_8_1427/_pdf.
«Inhibition of fatty acid synthase by amentoflavone reduces coxsackievirus B3 replication». Arch. Virol. 157 (2): 259–269. 2012. doi:10.1007/s00705-011-1164-z. PMID 22075919.
«Fatty acid synthase inhibition by amentoflavone suppresses HER2/neu (erbB2) oncogene in SKBR3 human breast cancer cells». Phytother Res 27 (5): 713–720. 2013. doi:10.1002/ptr.4778. PMID 22767439.
«Flavonoids as opioid receptor ligands: identification and preliminary structure-activity relationships». J. Nat. Prod. 70 (8): 1278–82. 2007. doi:10.1021/np070194x. PMID 17685652.
«Semisynthetic preparation of amentoflavone: A negative modulator at GABA(A) receptors». Bioorg. Med. Chem. Lett. 13 (14): 2281–4. 2003. doi:10.1016/s0960-894x(03)00434-7. PMID 12824018.
«Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects». Planta Med. 61 (3): 213–216. 1995. doi:10.1055/s-2006-958058. PMID 7617761.
«Anticancer mechanism of apigenin and the implications of GLUT-1 expression in head and neck cancers». Future Oncol 9 (9): 1353–1364. 2013. doi:10.2217/fon.13.84. PMID 23980682.
«Apigenin and its impact on gastrointestinal cancers». Mol Nutr Food Res 57 (1): 962–968. 2013. doi:10.1002/mnfr.201200424. PMID 23197449.
«Beneficial effects of green tea: a literature review» (PDF). Chin Med 5 (1): 1–9. 2010. doi:10.1186/1749-8546-5-13. PMID 20370896. PMC 2855614. http://link.springer.com/content/pdf/10.1186/1749-8546-5-13.pdf.
«Tea catechins' affinity for human cannabinoid receptors». Phytomedicine 17 (1): 19–22. 2010. doi:10.1016/j.phymed.2009.10.001. PMID 19897346.
«Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6». Food Chem. Toxicol. 59: 549–553. 2013. doi:10.1016/j.fct.2013.06.055. PMID 23835282.
«Antifungal activity of camptothecin, trifolin, and hyperoside isolated from Camptotheca acuminata». J. Agric. Food Chem. 53 (1): 32–37. 2005. doi:10.1021/jf0484780. PMID 15631505.
«Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/Bcl(XL)-regulated mitochondrial apoptotic pathway». Eur. J. Pharmacol. 672 (1-3): 45–55. 2011. doi:10.1016/j.ejphar.2011.09.177. PMID 21978835.
«Anti-inflammatory activity of hyperoside through the suppression of nuclear factor-κB activation in mouse peritoneal macrophages». Am. J. Chin. Med. 39 (1): 171–181. 2011. doi:10.1142/S0192415X11008737. PMID 21213407.
«The anti-immobility effect of hyperoside on the forced swimming test in rats is mediated by the D2-like receptors activation» (PDF). Planta Med. 77 (4): 334–339. 2011. doi:10.1055/s-0030-1250386. PMID 20945276. Αρχειοθετήθηκε από το πρωτότυπο στις 2013-12-16. https://web.archive.org/web/20131216111409/http://lib.kums.ac.ir/documents/10129/71808/334.pdf. Ανακτήθηκε στις 2016-02-18.
«Antidepressant-like effect of hyperoside isolated from Apocynum venetum leaves: possible cellular mechanisms». Phytomedicine 19 (2): 145–149. 2012. doi:10.1016/j.phymed.2011.06.029. PMID 21802268.
«MDR- and CYP3A4-mediated drug-herbal interactions». Life Sci. 78 (18): 2131–2145. 2006. doi:10.1016/j.lfs.2005.12.010. PMID 16442130.
«Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages» (PDF). Mediators Inflamm. 2007: 45673. 2007. doi:10.1155/2007/45673. PMID 18274639. PMC 2220047. http://downloads.hindawi.com/journals/mi/2007/045673.pdf.
«Kaempferol, a new nutrition-derived pan-inhibitor of human histone deacetylases». J. Nutr. Biochem. 24 (6): 977–985. 2013. doi:10.1016/j.jnutbio.2012.07.001. PMID 23159065.
«A review on the dietary flavonoid kaempferol». Mini Rev Med Chem 11 (4): 298–344. 2011. doi:10.2174/138955711795305335. PMID 21428901.
«Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin». Planta Med. 74 (14): 1667–1677. 2008. doi:10.1055/s-0028-1088314. PMID 18937165.
«Luteolin, a flavonoid with potential for cancer prevention and therapy» (PDF). Curr Cancer Drug Targets 8 (7): 634–646. 2008. doi:10.2174/156800908786241050. PMID 18991571. PMC 2615542. http://www.ncbi.nlm.nih.gov.elibrary.jcu.edu.au/pmc/articles/PMC2615542/pdf/nihms-82233.pdf. ^{[νεκρός σύνδεσμος]}
«Luteolin, a non-selective competitive inhibitor of phosphodiesterases 1-5, displaced [3H]-rolipram from high-affinity rolipram binding sites and reversed xylazine/ketamine-induced anesthesia». Eur. J. Pharmacol. 627 (1-3): 269–275. 2010. doi:10.1016/j.ejphar.2009.10.031. PMID 19853596.
«Quercetin: a potential drug to reverse multidrug resistance». Life Sci. 87 (11-12): 333–338. 2010. doi:10.1016/j.lfs.2010.07.004. PMID 20637779.
«Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships». Biochem. Pharmacol. 68 (10): 2087–2094. 2004. doi:10.1016/j.bcp.2004.06.030. PMID 15476679.
«A review on plant-based rutin extraction methods and its pharmacological activities». J Ethnopharmacol 150 (3): 805–817. 2013. doi:10.1016/j.jep.2013.10.036. PMID 24184193.
Hou, J; Fu, J; Zhang, ZM; Zhu, HL. «Biological activities and chemical modifications of caffeic acid derivatives». Fudan University Journal of Medical Sciences 38 (6): 546–552. doi:10.3969/j.issn.1672-8467.2011.06.017.
«Antihypertensive effects and mechanisms of chlorogenic acids». Hypertens. Res. 35 (4): 370–374. 2012. doi:10.1038/hr.2011.195. PMID 22072103.
«Quantitative phytochemical analyses of six hypericum species growing in slovenia». Planta Med. 65 (4): 388–90. 1999. doi:10.1055/s-2006-960798. PMID 17260265.
«Identification of the major constituents of Hypericum perforatum by LC/SPE/NMR and/or LC/MS». Phytochemistry 68 (3): 383–93. 2007. doi:10.1016/j.phytochem.2006.11.026. PMID 17196625.
«NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort» (PDF). J. Pharmacol. Sci. 102 (1): 47–54. 2006. doi:10.1254/jphs.FP0060378. PMID 16936454. https://www.jstage.jst.go.jp/article/jphs/102/1/102_1_47/_pdf.
«Skin tolerance of a new bath oil containing St. John's wort extract». Skin Pharmacol Physiol 21 (6): 306–311. 2008. doi:10.1159/000148223. PMID 18667843.
«Antimicrobial activity of seven hypericum entities from central Italy». Planta Med. 73 (6): 564–6. 2007. doi:10.1055/s-2007-967198. PMID 17516331.

doi.org

Anzenbacher, Pavel· Zanger, Ulrich M., επιμ. (2012). Metabolism of Drugs and Other Xenobiotics. Weinheim, Germany: Wiley-VCH. doi:10.1002/9783527630905. ISBN 978-3-527-63090-5.

drugbank.ca

«Hyperforin». Hyperforin. University of Alberta. http://www.drugbank.ca/drugs/DB01892#pharmacology. Ανακτήθηκε στις 5 December 2013.
«Hyperforin». Hyperforin. University of Alberta. http://www.drugbank.ca/drugs/DB01892. Ανακτήθηκε στις 4 December 2013.

duke.edu

sites.duke.edu

«St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature» (PDF). Psychopharmacology (Berl.) 153 (4): 402–414. February 2001. doi:10.1007/s002130000625. PMID 11243487. Αρχειοθετήθηκε από το πρωτότυπο στις 2014-06-11. https://web.archive.org/web/20140611050347/http://sites.duke.edu/greesonlab/files/2011/07/Greeson_etal_2001_Psychopharm-St.-Johns-Wort.pdf. Ανακτήθηκε στις 2016-02-18.

elsevier.com

linkinghub.elsevier.com

«Current St John's wort research from mode of action to clinical efficacy». Pharmacol. Res. 47 (2): 101–9. 2003. doi:10.1016/S1043-6618(02)00266-9. PMID 12543057. http://linkinghub.elsevier.com/retrieve/pii/S1043661802002669.

europa.eu

ema.europa.eu

«European Medicines Agency - Find medicine - Hypericum». www.ema.europa.eu. Αρχειοθετήθηκε από το πρωτότυπο στις 9 Ιουνίου 2016. Ανακτήθηκε στις 5 Μαΐου 2016.

hindawi.com

downloads.hindawi.com

«Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages» (PDF). Mediators Inflamm. 2007: 45673. 2007. doi:10.1155/2007/45673. PMID 18274639. PMC 2220047. http://downloads.hindawi.com/journals/mi/2007/045673.pdf.

iastate.edu

agron-agron.iastate.edu

Jack Dekker (1997). «The Soil Seed Bank». Agronomy Department, Iowa State University. Αρχειοθετήθηκε από το πρωτότυπο στις 22 Δεκεμβρίου 2015. Ανακτήθηκε στις 10 Δεκεμβρίου 2015.

invasive.org

«SPECIES: Hypericum perforatum» (PDF). Fire Effects Information System.

jcu.edu.au

jpet.aspetjournals.org.elibrary.jcu.edu.au

«Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression» (PDF). J. Pharmacol. Exp. Ther. 294 (1): 88–95. 2000. PMID 10871299. http://jpet.aspetjournals.org.elibrary.jcu.edu.au/content/294/1/88.full.pdf.

ncbi.nlm.nih.gov.elibrary.jcu.edu.au

«Luteolin, a flavonoid with potential for cancer prevention and therapy» (PDF). Curr Cancer Drug Targets 8 (7): 634–646. 2008. doi:10.2174/156800908786241050. PMID 18991571. PMC 2615542. http://www.ncbi.nlm.nih.gov.elibrary.jcu.edu.au/pmc/articles/PMC2615542/pdf/nihms-82233.pdf. ^{[νεκρός σύνδεσμος]}

jst.go.jp

jstage.jst.go.jp

«Fatty acid synthase inhibition by amentoflavone induces apoptosis and antiproliferation in human breast cancer cells» (PDF). Biol. Pharm. Bull. 32 (8): 1427–1432. 2009. doi:10.1248/bpb.32.1427. PMID 19652385. https://www.jstage.jst.go.jp/article/bpb/32/8/32_8_1427/_pdf.
«NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort» (PDF). J. Pharmacol. Sci. 102 (1): 47–54. 2006. doi:10.1254/jphs.FP0060378. PMID 16936454. https://www.jstage.jst.go.jp/article/jphs/102/1/102_1_47/_pdf.

kathimerini.gr

Στέφανος Γερουλάνος (26 Σεπτεμβρίου 2004). «Διοσκουρίδης, ο θεμελιωτής της Φαρμακολογίας». Καθημερινή. Ανακτήθηκε στις 19 Φεβρουαρίου 2009. ^{[νεκρός σύνδεσμος]}

kums.ac.ir

lib.kums.ac.ir

«The anti-immobility effect of hyperoside on the forced swimming test in rats is mediated by the D2-like receptors activation» (PDF). Planta Med. 77 (4): 334–339. 2011. doi:10.1055/s-0030-1250386. PMID 20945276. Αρχειοθετήθηκε από το πρωτότυπο στις 2013-12-16. https://web.archive.org/web/20131216111409/http://lib.kums.ac.ir/documents/10129/71808/334.pdf. Ανακτήθηκε στις 2016-02-18.

naturalstandard.com

«St. John's wort». Natural Standard. Cambridge, MA. Ανακτήθηκε στις 13 Δεκεμβρίου 2013.

nih.gov

ncbi.nlm.nih.gov

«Hyperforin». Hyperforin. University of Alberta. 30 June 2013. «Hyperforin is found in alcoholic beverages. Hyperforin is a constituent of Hypericum perforatum (St John's Wort) Hyperforin is a phytochemical produced by some of the members of the plant genus Hypericum, notably Hypericum perforatum (St John's wort). The structure of hyperforin was elucidated by a research group from the Shemyakin Institute of Bio-organic Chemistry (USSR Academy of Sciences in Moscow) and published in 1975. Hyperforin is a prenylated phloroglucinol derivative. Total synthesis of hyperforin has not yet been accomplished, despite attempts by several research groups. Hyperforin has been shown to exhibit anti-inflammatory, anti-tumor, antibiotic and anti-depressant functions (PMID 17696442 , 21751836 , 12725578 , 12018529 )
1. Arachidonate 5-lipoxygenase ...Specific function: Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes ...
2. Prostaglandin G/Η synthase 1 ... General function: Involved in peroxidase activity».
«Topical application of St. John's wort (Hypericum perforatum)». Planta Med. 80 (2-3): 109–20. 2014. doi:10.1055/s-0033-1351019. PMID 24214835. «Anti-inflammatory mechanisms of hyperforin have been described as inhibition of cyclooxygenase-1 (but not COX-2) and 5-lipoxygenase at low concentrations of 0.3 µmol/L and 1.2 µmol/L, respectively [52], and of PGE2 production in vitro [53] and in vivo with superior efficiency (ED50 = 1 mg/kg) compared to indomethacin (5 mg/kg) [54]. Hyperforin turned out to be a novel type of 5-lipoxygenase inhibitor with high effectivity in vivo [55] and suppressed oxidative bursts in polymorphonuclear cells at 1.8 µmol/L in vitro [56]. Inhibition of IFN-γ production, strong downregulation of CXCR3 expression on activated T cells, and downregulation of matrix metalloproteinase 9 expression caused Cabrelle et al. [57] to test the effectivity of hyperforin in a rat model of experimental allergic encephalomyelitis (EAE). Hyperforin attenuated the symptoms significantly, and the authors discussed hyperforin as a putative therapeutic molecule for the treatment of autoimmune inflammatory diseases sustained by Th1 cells.».
Klemow KM, Bartlow A, Crawford J, Kocher N, Shah J, Ritsick M (2011). «Chapter 11: Medical Attributes of St. John's Wort (Hypericum perforatum)». Στο: Benzie IFF, Sissi WG. Herbal Medicine Biomolecular and Clinical Aspects (2nd έκδοση). CRC Press. ISBN 9781439807163. Ανακτήθηκε στις 3 Δεκεμβρίου 2014. CS1 maint: Πολλαπλές ονομασίες: authors list (link)
«Hypericum perforatum (St John's Wort): a non-selective reuptake inhibitor? A review of the recent advances in its pharmacology». J. Psychopharmacol. (Oxford) 15 (1): 47–54. 2001. doi:10.1177/026988110101500109. PMID 11277608.
«Efficacy and acceptability of pharmacological treatments for depressive disorders in primary care: systematic review and network meta-analysis». Ann Fam Med 13 (1): 69–79. February 2015. doi:10.1370/afm.1687. PMID 25583895. «In network meta-analysis, tricyclic and tetracyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), a serotonin-noradrenaline reuptake inhibitor (SNRI; venlafaxine), a low-dose serotonin antagonist and reuptake inhibitor (SARI; trazodone) and hypericum extracts were found to be significantly superior to placebo, with estimated odds ratios between 1.69 and 2.03. There were no statistically significant differences between these drug classes. Reversible inhibitors of monoaminoxidase A (rMAO-As) and hypericum extracts were associated with significantly fewer dropouts because of adverse effects compared with TCAs, SSRIs, the SNRI, a noradrenaline reuptake inhibitor (NRI), and noradrenergic and specific serotonergic antidepressant agents (NaSSAs). ... TCAs and SSRIs have the most solid evidence base. Further agents (hypericum, rMAO-As, SNRI, NRI, NaSSAs, SARI) showed some positive results, but limitations of the currently available evidence makes a clear recommendation on their place in clinical practice difficult.».
Linde, Klaus, επιμ. (2008). «St John's wort for major depression». Cochrane Database Syst Rev (4): CD000448. doi:10.1002/14651858.CD000448.pub3. PMID 18843608.
Dörks, M; Langner, I; Dittmann, U; Timmer, A; Garbe, E (August 2013). «Antidepressant drug use and off-label prescribing in children and adolescents in Germany: results from a large population-based cohort study.». European child & adolescent psychiatry 22 (8): 511–8. doi:10.1007/s00787-013-0395-9. PMID 23455627.
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«Adverse reactions to St John's Wort». Can J Psychiatry 46 (1): 77–9. 2001. PMID 11221494. https://archive.org/details/sim_canadian-journal-of-psychiatry_2001-02_46_1/page/77.
Greeson, JM; Sanford, B; Monti, DA (Feb 2001). «St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature.». Psychopharmacology (Berl) 153 (4): 402–14. doi:10.1007/s002130000625. PMID 11243487. https://archive.org/details/sim_psychopharmacology_2001-02_153_4/page/402.
Hoban, Claire L.; Byard, Roger W.; Musgrave, Ian F. (Jul 2015). «A comparison of patterns of spontaneous adverse drug reaction reporting with St. John's Wort and fluoxetine during the period 2000-2013». Clinical and Experimental Pharmacology and Physiology 42: 747–51. doi:10.1111/1440-1681.12424. PMID 25988866. http://onlinelibrary.wiley.com/doi/10.1111/1440-1681.12424/abstract. Ανακτήθηκε στις 7 June 2015. «The organ systems affected by ADRs to St John's Wort and fluoxetine have a similar profile, with the majority of cases affecting the central nervous system (45.2%, 61.7%).».
«Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and females» (PDF). Br J Clin Pharmacol 57 (4): 495–499. 2004. doi:10.1111/j.1365-2125.2003.02049.x. PMID 15025748. PMC 1884478. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884478/pdf/bcp0057-0495.pdf.
«Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics». Mol Nutr Food Res 52 (7): 772–9. 2008. doi:10.1002/mnfr.200700081. PMID 18214850.
Russo, Emilio; Scicchitano, Francesca; Whalley, Benjamin J.; Mazzitello, Carmela; Ciriaco, Miriam; Esposito, Stefania; Patanè, Marinella; Upton, Roy και άλλοι. (May 2014). «Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions.». Phytotherapy Research 28 (5): 643–655. doi:10.1002/ptr.5050. PMID 23897801.
Tirona, RG; Bailey, DG (June 2006). «Herbal product-drug interactions mediated by induction.». British Journal of Clinical Pharmacology 61 (6): 677–81. doi:10.1111/j.1365-2125.2006.02684.x. PMID 16722828. https://archive.org/details/sim_british-journal-of-clinical-pharmacology_2006-06_61_6/page/677.
Borrelli, F; Izzo, AA (December 2009). «Herb-drug interactions with St John's wort (Hypericum perforatum): an update on clinical observations.». The AAPS journal 11 (4): 710–27. doi:10.1208/s12248-009-9146-8. PMID 19859815.
«Biologically active and other chemical constituents of the herb of Hypericum perforatum L». Pharmacopsychiatry 30 Suppl 2 (Suppl 2): 129–34. 1997. doi:10.1055/s-2007-979533. PMID 9342774.
«Mechanism of action of St John's wort in depression : what is known?». CNS Drugs 17 (8): 539–62. 2003. doi:10.2165/00023210-200317080-00001. PMID 12775192. http://link.springer.com/content/pdf/10.2165/00023210-200317080-00001.pdf.
«Current St John's wort research from mode of action to clinical efficacy». Pharmacol. Res. 47 (2): 101–9. 2003. doi:10.1016/S1043-6618(02)00266-9. PMID 12543057. http://linkinghub.elsevier.com/retrieve/pii/S1043661802002669.
«St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature» (PDF). Psychopharmacology (Berl.) 153 (4): 402–414. February 2001. doi:10.1007/s002130000625. PMID 11243487. Αρχειοθετήθηκε από το πρωτότυπο στις 2014-06-11. https://web.archive.org/web/20140611050347/http://sites.duke.edu/greesonlab/files/2011/07/Greeson_etal_2001_Psychopharm-St.-Johns-Wort.pdf. Ανακτήθηκε στις 2016-02-18.
«Adhyperforin as a contributor to the effect of Hypericum perforatum L. in biochemical models of antidepressant activity». Life Sci. 68 (14): 1593–1605. 2001. doi:10.1016/S0024-3205(01)00946-8. PMID 11263672.
«St. John's wort and its constituent hyperforin concordantly regulate expression of genes encoding enzymes involved in basic cellular pathways». Pharmacogenet. Genomics 15 (11): 817–829. 2005. doi:10.1097/01.fpc.0000175597.60066.3d. PMID 16220113.
«Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression» (PDF). J. Pharmacol. Exp. Ther. 294 (1): 88–95. 2000. PMID 10871299. http://jpet.aspetjournals.org.elibrary.jcu.edu.au/content/294/1/88.full.pdf.
«Hypericin--the facts about a controversial agent» (PDF). Curr. Pharm. Des. 11 (2): 233–253. 2005. doi:10.2174/1381612053382287. PMID 15638760. Αρχειοθετήθηκε από το πρωτότυπο στις 2013-10-05. https://web.archive.org/web/20131005011912/http://www.benthamscience.com/cpd/sample/cpd11-2/0007B.pdf. Ανακτήθηκε στις 2016-02-18.
«Catalytic inhibition of human DNA topoisomerase IIalpha by hypericin, a naphthodianthrone from St. John's wort (Hypericum perforatum)». Biochem. Pharmacol. 62 (8): 1059–1070. 2001. doi:10.1016/S0006-2952(01)00759-6. PMID 11597574.
«Single-dose and steady-state pharmacokinetics of hypericin and pseudohypericin» (PDF). Antimicrob. Agents Chemother. 40 (9): 2087–2093. 1996. PMID 8878586. PMC 163478. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC163478/pdf/402087.pdf.
«Therapeutic agents with dramatic antiretroviral activity and little toxicity at effective doses: aromatic polycyclic diones hypericin and pseudohypericin» (PDF). Proc. Natl. Acad. Sci. U.S.A. 85 (14): 5230–5234. 1988. doi:10.1073/pnas.85.14.5230. PMID 2839837. PMC 281723. http://www.pnas.org/content/85/14/5230.full.pdf.
«Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin» (PDF). Proc. Natl. Acad. Sci. U.S.A. 86 (15): 5963–5967. 1989. doi:10.1073/pnas.86.15.5963. PMID 2548193. PMC 297751. http://www.pnas.org/content/86/15/5963.full.pdf.
«Hypericin and pseudohypericin specifically inhibit protein kinase C: possible relation to their antiretroviral activity». Biochem. Biophys. Res. Commun. 165 (3): December 1989. 1989. doi:10.1016/0006-291X(89)92730-7. PMID 2558652.
«Inhibition of human cytochromes P450 by components of Ginkgo biloba». J. Pharm. Pharmacol. 56 (8): 1039–1044. 2004. doi:10.1211/0022357044021. PMID 15285849.
«Fatty acid synthase inhibition by amentoflavone induces apoptosis and antiproliferation in human breast cancer cells» (PDF). Biol. Pharm. Bull. 32 (8): 1427–1432. 2009. doi:10.1248/bpb.32.1427. PMID 19652385. https://www.jstage.jst.go.jp/article/bpb/32/8/32_8_1427/_pdf.
«Inhibition of fatty acid synthase by amentoflavone reduces coxsackievirus B3 replication». Arch. Virol. 157 (2): 259–269. 2012. doi:10.1007/s00705-011-1164-z. PMID 22075919.
«Fatty acid synthase inhibition by amentoflavone suppresses HER2/neu (erbB2) oncogene in SKBR3 human breast cancer cells». Phytother Res 27 (5): 713–720. 2013. doi:10.1002/ptr.4778. PMID 22767439.
«Flavonoids as opioid receptor ligands: identification and preliminary structure-activity relationships». J. Nat. Prod. 70 (8): 1278–82. 2007. doi:10.1021/np070194x. PMID 17685652.
«Semisynthetic preparation of amentoflavone: A negative modulator at GABA(A) receptors». Bioorg. Med. Chem. Lett. 13 (14): 2281–4. 2003. doi:10.1016/s0960-894x(03)00434-7. PMID 12824018.
«Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects». Planta Med. 61 (3): 213–216. 1995. doi:10.1055/s-2006-958058. PMID 7617761.
«Anticancer mechanism of apigenin and the implications of GLUT-1 expression in head and neck cancers». Future Oncol 9 (9): 1353–1364. 2013. doi:10.2217/fon.13.84. PMID 23980682.
«Apigenin and its impact on gastrointestinal cancers». Mol Nutr Food Res 57 (1): 962–968. 2013. doi:10.1002/mnfr.201200424. PMID 23197449.
«Beneficial effects of green tea: a literature review» (PDF). Chin Med 5 (1): 1–9. 2010. doi:10.1186/1749-8546-5-13. PMID 20370896. PMC 2855614. http://link.springer.com/content/pdf/10.1186/1749-8546-5-13.pdf.
«Tea catechins' affinity for human cannabinoid receptors». Phytomedicine 17 (1): 19–22. 2010. doi:10.1016/j.phymed.2009.10.001. PMID 19897346.
«Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6». Food Chem. Toxicol. 59: 549–553. 2013. doi:10.1016/j.fct.2013.06.055. PMID 23835282.
«Antifungal activity of camptothecin, trifolin, and hyperoside isolated from Camptotheca acuminata». J. Agric. Food Chem. 53 (1): 32–37. 2005. doi:10.1021/jf0484780. PMID 15631505.
«Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/Bcl(XL)-regulated mitochondrial apoptotic pathway». Eur. J. Pharmacol. 672 (1-3): 45–55. 2011. doi:10.1016/j.ejphar.2011.09.177. PMID 21978835.
«Anti-inflammatory activity of hyperoside through the suppression of nuclear factor-κB activation in mouse peritoneal macrophages». Am. J. Chin. Med. 39 (1): 171–181. 2011. doi:10.1142/S0192415X11008737. PMID 21213407.
«The anti-immobility effect of hyperoside on the forced swimming test in rats is mediated by the D2-like receptors activation» (PDF). Planta Med. 77 (4): 334–339. 2011. doi:10.1055/s-0030-1250386. PMID 20945276. Αρχειοθετήθηκε από το πρωτότυπο στις 2013-12-16. https://web.archive.org/web/20131216111409/http://lib.kums.ac.ir/documents/10129/71808/334.pdf. Ανακτήθηκε στις 2016-02-18.
«Antidepressant-like effect of hyperoside isolated from Apocynum venetum leaves: possible cellular mechanisms». Phytomedicine 19 (2): 145–149. 2012. doi:10.1016/j.phymed.2011.06.029. PMID 21802268.
«MDR- and CYP3A4-mediated drug-herbal interactions». Life Sci. 78 (18): 2131–2145. 2006. doi:10.1016/j.lfs.2005.12.010. PMID 16442130.
«Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages» (PDF). Mediators Inflamm. 2007: 45673. 2007. doi:10.1155/2007/45673. PMID 18274639. PMC 2220047. http://downloads.hindawi.com/journals/mi/2007/045673.pdf.
«Kaempferol, a new nutrition-derived pan-inhibitor of human histone deacetylases». J. Nutr. Biochem. 24 (6): 977–985. 2013. doi:10.1016/j.jnutbio.2012.07.001. PMID 23159065.
«A review on the dietary flavonoid kaempferol». Mini Rev Med Chem 11 (4): 298–344. 2011. doi:10.2174/138955711795305335. PMID 21428901.
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«Luteolin, a flavonoid with potential for cancer prevention and therapy» (PDF). Curr Cancer Drug Targets 8 (7): 634–646. 2008. doi:10.2174/156800908786241050. PMID 18991571. PMC 2615542. http://www.ncbi.nlm.nih.gov.elibrary.jcu.edu.au/pmc/articles/PMC2615542/pdf/nihms-82233.pdf. ^{[νεκρός σύνδεσμος]}
«A case series of a luteolin formulation (NeuroProtek®) in children with autism spectrum disorders». Int J Immunopathol Pharmacol 25 (2): 317–323. April–June 2012. PMID 22697063.
«Luteolin, a non-selective competitive inhibitor of phosphodiesterases 1-5, displaced [3H]-rolipram from high-affinity rolipram binding sites and reversed xylazine/ketamine-induced anesthesia». Eur. J. Pharmacol. 627 (1-3): 269–275. 2010. doi:10.1016/j.ejphar.2009.10.031. PMID 19853596.
«Quercetin: a potential drug to reverse multidrug resistance». Life Sci. 87 (11-12): 333–338. 2010. doi:10.1016/j.lfs.2010.07.004. PMID 20637779.
«Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships». Biochem. Pharmacol. 68 (10): 2087–2094. 2004. doi:10.1016/j.bcp.2004.06.030. PMID 15476679.
«A review on plant-based rutin extraction methods and its pharmacological activities». J Ethnopharmacol 150 (3): 805–817. 2013. doi:10.1016/j.jep.2013.10.036. PMID 24184193.
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«Pharmacokinetics of tea catechins after ingestion of green tea and (−)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability» (PDF). Cancer Epidemiol. Biomarkers Prev. 11 (10 Pt 1): 1025–1032. 2002. PMID 12376503. http://cebp.aacrjournals.org/content/11/10/1025.full.pdf.
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«Quantitative phytochemical analyses of six hypericum species growing in slovenia». Planta Med. 65 (4): 388–90. 1999. doi:10.1055/s-2006-960798. PMID 17260265.
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«NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort» (PDF). J. Pharmacol. Sci. 102 (1): 47–54. 2006. doi:10.1254/jphs.FP0060378. PMID 16936454. https://www.jstage.jst.go.jp/article/jphs/102/1/102_1_47/_pdf.
«Skin tolerance of a new bath oil containing St. John's wort extract». Skin Pharmacol Physiol 21 (6): 306–311. 2008. doi:10.1159/000148223. PMID 18667843.
«Antimicrobial activity of seven hypericum entities from central Italy». Planta Med. 73 (6): 564–6. 2007. doi:10.1055/s-2007-967198. PMID 17516331.

pubmedcentral.nih.gov

«Efficacy and acceptability of pharmacological treatments for depressive disorders in primary care: systematic review and network meta-analysis». Ann Fam Med 13 (1): 69–79. February 2015. doi:10.1370/afm.1687. PMID 25583895. «In network meta-analysis, tricyclic and tetracyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), a serotonin-noradrenaline reuptake inhibitor (SNRI; venlafaxine), a low-dose serotonin antagonist and reuptake inhibitor (SARI; trazodone) and hypericum extracts were found to be significantly superior to placebo, with estimated odds ratios between 1.69 and 2.03. There were no statistically significant differences between these drug classes. Reversible inhibitors of monoaminoxidase A (rMAO-As) and hypericum extracts were associated with significantly fewer dropouts because of adverse effects compared with TCAs, SSRIs, the SNRI, a noradrenaline reuptake inhibitor (NRI), and noradrenergic and specific serotonergic antidepressant agents (NaSSAs). ... TCAs and SSRIs have the most solid evidence base. Further agents (hypericum, rMAO-As, SNRI, NRI, NaSSAs, SARI) showed some positive results, but limitations of the currently available evidence makes a clear recommendation on their place in clinical practice difficult.».
«Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and females» (PDF). Br J Clin Pharmacol 57 (4): 495–499. 2004. doi:10.1111/j.1365-2125.2003.02049.x. PMID 15025748. PMC 1884478. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884478/pdf/bcp0057-0495.pdf.
«Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics». Mol Nutr Food Res 52 (7): 772–9. 2008. doi:10.1002/mnfr.200700081. PMID 18214850.
«Single-dose and steady-state pharmacokinetics of hypericin and pseudohypericin» (PDF). Antimicrob. Agents Chemother. 40 (9): 2087–2093. 1996. PMID 8878586. PMC 163478. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC163478/pdf/402087.pdf.
«Therapeutic agents with dramatic antiretroviral activity and little toxicity at effective doses: aromatic polycyclic diones hypericin and pseudohypericin» (PDF). Proc. Natl. Acad. Sci. U.S.A. 85 (14): 5230–5234. 1988. doi:10.1073/pnas.85.14.5230. PMID 2839837. PMC 281723. http://www.pnas.org/content/85/14/5230.full.pdf.
«Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin» (PDF). Proc. Natl. Acad. Sci. U.S.A. 86 (15): 5963–5967. 1989. doi:10.1073/pnas.86.15.5963. PMID 2548193. PMC 297751. http://www.pnas.org/content/86/15/5963.full.pdf.
«Flavonoids as opioid receptor ligands: identification and preliminary structure-activity relationships». J. Nat. Prod. 70 (8): 1278–82. 2007. doi:10.1021/np070194x. PMID 17685652.
«Beneficial effects of green tea: a literature review» (PDF). Chin Med 5 (1): 1–9. 2010. doi:10.1186/1749-8546-5-13. PMID 20370896. PMC 2855614. http://link.springer.com/content/pdf/10.1186/1749-8546-5-13.pdf.
«Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages» (PDF). Mediators Inflamm. 2007: 45673. 2007. doi:10.1155/2007/45673. PMID 18274639. PMC 2220047. http://downloads.hindawi.com/journals/mi/2007/045673.pdf.
«Luteolin, a flavonoid with potential for cancer prevention and therapy» (PDF). Curr Cancer Drug Targets 8 (7): 634–646. 2008. doi:10.2174/156800908786241050. PMID 18991571. PMC 2615542. http://www.ncbi.nlm.nih.gov.elibrary.jcu.edu.au/pmc/articles/PMC2615542/pdf/nihms-82233.pdf. ^{[νεκρός σύνδεσμος]}

pubchem.ncbi.nlm.nih.gov

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