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(+)-CPCA (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "(+)-CPCA" in English language version.

refsWebsite
Global rank English rank
39doi.org
2nd place
2nd place
39nih.gov
4th place
4th place
6semanticscholar.org
11th place
8th place
5espacenet.com
800th place
676th place
1zenodo.org
621st place
380th place
1organic-chemistry.org
low place
low place

doi.org

  • Mobele BI, Kinahan T, Ulysse LG, Gagnier SV, Ironside MD, Knox GS, Mohammadi F (2006). "Process Development toward the Pilot Scale Synthesis of the Piperidine-Based Cocaine Analogue and Potent Dopamine and Norepinephrine Reuptake Inhibitor CTDP 31,446". Organic Process Research & Development. 10 (5): 914–920. doi:10.1021/op060114g.
  • Kozikowski AP, Araldi GL, Boja J, Meil WM, Johnson KM, Flippen-Anderson JL, et al. (May 1998). "Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton". Journal of Medicinal Chemistry. 41 (11): 1962–1969. doi:10.1021/jm980028+. PMID 9599245.
  • Provencher BA, Eshleman AJ, Johnson RA, Shi X, Kryatova O, Nelson J, et al. (October 2018). "Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter". Journal of Medicinal Chemistry. 61 (20): 9121–9131. doi:10.1021/acs.jmedchem.8b00542. PMID 30240563. S2CID 52312790.
  • Jiang S, Chang AC, Abraham P, Kuhar MJ, Carroll FI (December 1998). "Synthesis and transporter binding properties of (R)-2β,3β- and (R)-2α,3α-diaryltropanes". Bioorganic & Medicinal Chemistry Letters. 8 (24): 3689–92. doi:10.1016/s0960-894x(98)00673-8. PMID 9934496.
  • Hauck AE, Giam CS (1980). "Regioselective nucleophilic addition of organolithium compounds to 3-(4,4-dimethyloxazolin-2-yl)pyridine". Journal of the Chemical Society, Perkin Transactions 1: 2070. doi:10.1039/p19800002070.
  • Shao L, Li W, Xie Q, Yin H (February 2014). "Triple reuptake inhibitors: a patent review (2006 - 2012)". Expert Opinion on Therapeutic Patents. 24 (2): 131–154. doi:10.1517/13543776.2014.859676. PMID 24289044. S2CID 1825304.
  • Deutsch HM, Shi Q, Gruszecka-Kowalik E, Schweri MM (March 1996). "Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs". Journal of Medicinal Chemistry. 39 (6): 1201–1209. doi:10.1021/jm950697c. PMID 8632426.
  • Schweri MM, Deutsch HM, Massey AT, Holtzman SG (May 2002). "Biochemical and behavioral characterization of novel methylphenidate analogs". The Journal of Pharmacology and Experimental Therapeutics. 301 (2): 527–535. doi:10.1124/jpet.301.2.527. PMID 11961053.
  • Lomenzo SA, Rhoden JB, Izenwasser S, Wade D, Kopajtic T, Katz JL, Trudell ML (March 2005). "Synthesis and biological evaluation of meperidine analogues at monoamine transporters". Journal of Medicinal Chemistry. 48 (5): 1336–1343. doi:10.1021/jm0401614. PMID 15743177.
  • Rhoden JB, Bouvet M, Izenwasser S, Wade D, Lomenzo SA, Trudell ML (October 2005). "Structure-activity studies of 3'-4'-dichloro-meperidine analogues at dopamine and serotonin transporters". Bioorganic & Medicinal Chemistry. 13 (19): 5623–5634. doi:10.1016/j.bmc.2005.05.025. PMID 15993612.
  • Shao L, Hewitt MC, Wang F, Malcolm SC, Ma J, Campbell JE, et al. (March 2011). "Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor". Bioorganic & Medicinal Chemistry Letters. 21 (5): 1438–1441. doi:10.1016/j.bmcl.2011.01.016. PMID 21310609.
  • Shao L, Hewitt MC, Wang F, Malcolm SC, Ma J, Campbell JE, et al. (March 2011). "Discovery of N-methyl-1-(1-phenylcyclohexyl)ethanamine, a novel triple serotonin, norepinephrine and dopamine reuptake inhibitor". Bioorganic & Medicinal Chemistry Letters. 21 (5): 1434–1437. doi:10.1016/j.bmcl.2011.01.019. PMID 21310612.
  • Lomenzo SA, Rhoden JB, Izenwasser S, Wade D, Kopajtic T, Katz JL, Trudell ML (March 2005). "Synthesis and biological evaluation of meperidine analogues at monoamine transporters". Journal of Medicinal Chemistry. 48 (5): 1336–1343. doi:10.1021/jm0401614. PMID 15743177.
  • Zou MF, Cao J, Kopajtic T, Desai RI, Katz JL, Newman AH (October 2006). "Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation". Journal of Medicinal Chemistry. 49 (21): 6391–6399. doi:10.1021/jm060762q. PMID 17034144.
  • Matsumoto RR, Hewett KL, Pouw B, Bowen WD, Husbands SM, Cao JJ, Newman AH (December 2001). "Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters". Neuropharmacology. 41 (7): 878–886. doi:10.1016/S0028-3908(01)00116-2. PMID 11684152. S2CID 44328858.
  • Matsumoto RR, McCracken KA, Friedman MJ, Pouw B, De Costa BR, Bowen WD (May 2001). "Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice". European Journal of Pharmacology. 419 (2–3): 163–174. doi:10.1016/S0014-2999(01)00968-2. PMID 11426838.
  • Matsumoto RR, McCracken KA, Pouw B, Zhang Y, Bowen WD (June 2002). "Involvement of sigma receptors in the behavioral effects of cocaine: evidence from novel ligands and antisense oligodeoxynucleotides". Neuropharmacology. 42 (8): 1043–1055. doi:10.1016/S0028-3908(02)00056-4. PMID 12128006. S2CID 34846910.
  • Matsumoto RR, Liu Y, Lerner M, Howard EW, Brackett DJ (May 2003). "Sigma receptors: potential medications development target for anti-cocaine agents". European Journal of Pharmacology. 469 (1–3): 1–12. doi:10.1016/S0014-2999(03)01723-0. PMID 12782179.
  • Su TP, Hayashi T (October 2003). "Understanding the molecular mechanism of sigma-1 receptors: towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction". Current Medicinal Chemistry. 10 (20): 2073–2080. doi:10.2174/0929867033456783. PMID 12871086.
  • Nguyen EC, McCracken KA, Liu Y, Pouw B, Matsumoto RR (October 2005). "Involvement of sigma (sigma) receptors in the acute actions of methamphetamine: receptor binding and behavioral studies". Neuropharmacology. 49 (5): 638–645. doi:10.1016/j.neuropharm.2005.04.016. PMID 15939443. S2CID 41068558.
  • Wang J, Mack AL, Coop A, Matsumoto RR (November 2007). "Novel sigma (sigma) receptor agonists produce antidepressant-like effects in mice". European Neuropsychopharmacology. 17 (11): 708–716. doi:10.1016/j.euroneuro.2007.02.007. PMC 4041597. PMID 17376658.
  • Xu L, Trudell ML (November 1996). "Stereoselective synthesis of 2β-carbomethoxy-3β-phenyltropane derivatives. Enhanced stereoselectivity observed for the conjugate addition reaction of phenylmagnesium bromide derivatives with anhydro dichloromethane". Journal of Heterocyclic Chemistry. 33 (6): 2037–2039. doi:10.1002/jhet.5570330676.
  • Petukhov PA, Zhang J, Kozikowski AP, Wang CZ, Ye YP, Johnson KM, Tella SR (July 2002). "SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement". Journal of Medicinal Chemistry. 45 (15): 3161–3170. doi:10.1021/jm0200153. PMID 12109901.
  • Froimowitz M, Gu Y, Dakin LA, Nagafuji PM, Kelley CJ, Parrish D, et al. (January 2007). "Slow-onset, long-duration, alkyl analogues of methylphenidate with enhanced selectivity for the dopamine transporter". Journal of Medicinal Chemistry. 50 (2): 219–232. doi:10.1021/jm0608614. PMID 17228864.
  • Wang S, Sakamuri S, Enyedy IJ, Kozikowski AP, Deschaux O, Bandyopadhyay BC, et al. (February 2000). "Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationships, and behavioral pharmacological studies". Journal of Medicinal Chemistry. 43 (3): 351–360. doi:10.1021/jm990516x. PMID 10669562.
  • Chiamulera C, Epping-Jordan MP, Zocchi A, Marcon C, Cottiny C, Tacconi S, et al. (September 2001). "Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice". Nature Neuroscience. 4 (9): 873–874. doi:10.1038/nn0901-873. PMID 11528416. S2CID 1314227.
  • Petukhov PA, Zhang J, Wang CZ, Ye YP, Johnson KM, Kozikowski AP (June 2004). "Synthesis, molecular modeling, and biological studies of novel piperidine-based analogues of cocaine: evidence of unfavorable interactions proximal to the 3alpha-position of the piperidine ring". Journal of Medicinal Chemistry. 47 (12): 3009–3018. doi:10.1021/jm0303296. PMID 15163183.
  • Yuan H, Kozikowski AP, Petukhov PA (December 2004). "CoMFA study of piperidine analogues of cocaine at the dopamine transporter: exploring the binding mode of the 3 alpha-substituent of the piperidine ring using pharmacophore-based flexible alignment". Journal of Medicinal Chemistry. 47 (25): 6137–6143. doi:10.1021/jm049544s. PMID 15566285.
  • Lieske SF, Yang B, Eldefrawi ME, MacKerell AD, Wright J (March 1998). "(-)-3 beta-Substituted ecgonine methyl esters as inhibitors for cocaine binding and dopamine uptake". Journal of Medicinal Chemistry. 41 (6): 864–876. doi:10.1021/jm970025h. PMID 9526561.
  • Petukhov PA, Zhang M, Johnson KJ, Tella SR, Kozikowski AP (August 2001). "Sar studies of piperidine-based analogues of cocaine. Part 3: oxadiazoles". Bioorganic & Medicinal Chemistry Letters. 11 (16): 2079–2083. doi:10.1016/S0960-894X(01)00379-1. PMID 11514143.
  • Tamiz AP, Bandyopadhyay BC, Zhang J, Flippen-Anderson JL, Zhang M, Wang CZ, et al. (May 2001). "Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors". Journal of Medicinal Chemistry. 44 (10): 1615–1622. doi:10.1021/jm000552s. PMID 11334571.
  • Amat M, Bosch J, Hidalgo J, Cantó M, Pérez M, Llor N, et al. (May 2000). "Synthesis of enantiopure trans-3,4-disubstituted piperidines. An enantiodivergent synthesis of (+)- and (-)-paroxetine". The Journal of Organic Chemistry. 65 (10): 3074–3084. doi:10.1021/jo991816p. PMID 10814199.
  • Johnson TA, Jang DO, Slafer BW, Curtis MD, Beak P (October 2002). "Asymmetric carbon-carbon bond formations in conjugate additions of lithiated N-Boc allylic and benzylic amines to nitroalkenes: enantioselective synthesis of substituted piperidines, pyrrolidines, and pyrimidinones". Journal of the American Chemical Society. 124 (39): 11689–11698. doi:10.1021/ja0271375. PMID 12296735.
  • Tamiz AP, Zhang J, Flippen-Anderson JL, Zhang M, Johnson KM, Deschaux O, et al. (March 2000). "Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors". Journal of Medicinal Chemistry. 43 (6): 1215–1222. doi:10.1021/jm9905561. PMID 10737754.
  • Zhou J, He R, Johnson KM, Ye Y, Kozikowski AP (November 2004). "Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization". Journal of Medicinal Chemistry. 47 (24): 5821–5824. doi:10.1021/jm040117o. PMC 1395211. PMID 15537337.
  • He R, Kurome T, Giberson KM, Johnson KM, Kozikowski AP (December 2005). "Further structure-activity relationship studies of piperidine-based monoamine transporter inhibitors: effects of piperidine ring stereochemistry on potency. Identification of norepinephrine transporter selective ligands and broad-spectrum transporter inhibitors". Journal of Medicinal Chemistry. 48 (25): 7970–7979. doi:10.1021/jm050694s. PMID 16335921.
  • Musachio JL, Hong J, Ichise M, Seneca N, Brown AK, Liow JS, et al. (June 2006). "Development of new brain imaging agents based upon nocaine-modafinil hybrid monoamine transporter inhibitors". Bioorganic & Medicinal Chemistry Letters. 16 (12): 3101–3104. doi:10.1016/j.bmcl.2006.03.066. PMID 16621532.
  • Zhou J (December 2004). "Norepinephrine transporter inhibitors and their therapeutic potential". Drugs of the Future. 29 (12): 1235–1244. doi:10.1358/dof.2004.029.12.855246. PMC 1518795. PMID 16871320.
  • Yuan H, Petukhov PA (December 2006). "Improved 3D-QSAR CoMFA of the dopamine transporter blockers with multiple conformations using the genetic algorithm". Bioorganic & Medicinal Chemistry Letters. 16 (24): 6267–6272. doi:10.1016/j.bmcl.2006.09.037. PMID 17027270.

espacenet.com

worldwide.espacenet.com

  • EP 2617704, Shao, Liming; Wang, Fengjiang & Malcolm, Scott Christopher et al., "Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors", published 2017-06-28, assigned to Sunovion Pharmaceuticals Inc. 
  • US 7560562, Wätjen, Frank, "Piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors", published 2009-07-14, assigned to Neuroesearch AS 
  • WO application 0232870, Ward, Neal, "Process of the preparation of 3-substituted-4-aryl piperidine compounds", published 2002-04-25, assigned to SmithKline Beecham plc 
  • WO application 0129032, Crowe, David; Ward, Neal & Wells, Andrew Stephen, "Process for the preparation of paroxetine", published 2001-04-26, assigned to SmithKline Beecham plc 
  • WO 0117966, Crowe, David; Jones, David Alan & Ward, Neal, "Process for the preparation of 1-methyl-3-carbomethoxy-4-(4'-fluorophenyl)-piperidine", published 2001-03-15, assigned to SmithKline Beecham plc 

nih.gov

pubmed.ncbi.nlm.nih.gov

  • Kozikowski AP, Araldi GL, Boja J, Meil WM, Johnson KM, Flippen-Anderson JL, et al. (May 1998). "Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton". Journal of Medicinal Chemistry. 41 (11): 1962–1969. doi:10.1021/jm980028+. PMID 9599245.
  • Provencher BA, Eshleman AJ, Johnson RA, Shi X, Kryatova O, Nelson J, et al. (October 2018). "Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter". Journal of Medicinal Chemistry. 61 (20): 9121–9131. doi:10.1021/acs.jmedchem.8b00542. PMID 30240563. S2CID 52312790.
  • Jiang S, Chang AC, Abraham P, Kuhar MJ, Carroll FI (December 1998). "Synthesis and transporter binding properties of (R)-2β,3β- and (R)-2α,3α-diaryltropanes". Bioorganic & Medicinal Chemistry Letters. 8 (24): 3689–92. doi:10.1016/s0960-894x(98)00673-8. PMID 9934496.
  • Shao L, Li W, Xie Q, Yin H (February 2014). "Triple reuptake inhibitors: a patent review (2006 - 2012)". Expert Opinion on Therapeutic Patents. 24 (2): 131–154. doi:10.1517/13543776.2014.859676. PMID 24289044. S2CID 1825304.
  • Deutsch HM, Shi Q, Gruszecka-Kowalik E, Schweri MM (March 1996). "Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs". Journal of Medicinal Chemistry. 39 (6): 1201–1209. doi:10.1021/jm950697c. PMID 8632426.
  • Schweri MM, Deutsch HM, Massey AT, Holtzman SG (May 2002). "Biochemical and behavioral characterization of novel methylphenidate analogs". The Journal of Pharmacology and Experimental Therapeutics. 301 (2): 527–535. doi:10.1124/jpet.301.2.527. PMID 11961053.
  • Lomenzo SA, Rhoden JB, Izenwasser S, Wade D, Kopajtic T, Katz JL, Trudell ML (March 2005). "Synthesis and biological evaluation of meperidine analogues at monoamine transporters". Journal of Medicinal Chemistry. 48 (5): 1336–1343. doi:10.1021/jm0401614. PMID 15743177.
  • Rhoden JB, Bouvet M, Izenwasser S, Wade D, Lomenzo SA, Trudell ML (October 2005). "Structure-activity studies of 3'-4'-dichloro-meperidine analogues at dopamine and serotonin transporters". Bioorganic & Medicinal Chemistry. 13 (19): 5623–5634. doi:10.1016/j.bmc.2005.05.025. PMID 15993612.
  • Shao L, Hewitt MC, Wang F, Malcolm SC, Ma J, Campbell JE, et al. (March 2011). "Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor". Bioorganic & Medicinal Chemistry Letters. 21 (5): 1438–1441. doi:10.1016/j.bmcl.2011.01.016. PMID 21310609.
  • Shao L, Hewitt MC, Wang F, Malcolm SC, Ma J, Campbell JE, et al. (March 2011). "Discovery of N-methyl-1-(1-phenylcyclohexyl)ethanamine, a novel triple serotonin, norepinephrine and dopamine reuptake inhibitor". Bioorganic & Medicinal Chemistry Letters. 21 (5): 1434–1437. doi:10.1016/j.bmcl.2011.01.019. PMID 21310612.
  • Lomenzo SA, Rhoden JB, Izenwasser S, Wade D, Kopajtic T, Katz JL, Trudell ML (March 2005). "Synthesis and biological evaluation of meperidine analogues at monoamine transporters". Journal of Medicinal Chemistry. 48 (5): 1336–1343. doi:10.1021/jm0401614. PMID 15743177.
  • Zou MF, Cao J, Kopajtic T, Desai RI, Katz JL, Newman AH (October 2006). "Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation". Journal of Medicinal Chemistry. 49 (21): 6391–6399. doi:10.1021/jm060762q. PMID 17034144.
  • Matsumoto RR, Hewett KL, Pouw B, Bowen WD, Husbands SM, Cao JJ, Newman AH (December 2001). "Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters". Neuropharmacology. 41 (7): 878–886. doi:10.1016/S0028-3908(01)00116-2. PMID 11684152. S2CID 44328858.
  • Matsumoto RR, McCracken KA, Friedman MJ, Pouw B, De Costa BR, Bowen WD (May 2001). "Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice". European Journal of Pharmacology. 419 (2–3): 163–174. doi:10.1016/S0014-2999(01)00968-2. PMID 11426838.
  • Matsumoto RR, McCracken KA, Pouw B, Zhang Y, Bowen WD (June 2002). "Involvement of sigma receptors in the behavioral effects of cocaine: evidence from novel ligands and antisense oligodeoxynucleotides". Neuropharmacology. 42 (8): 1043–1055. doi:10.1016/S0028-3908(02)00056-4. PMID 12128006. S2CID 34846910.
  • Matsumoto RR, Liu Y, Lerner M, Howard EW, Brackett DJ (May 2003). "Sigma receptors: potential medications development target for anti-cocaine agents". European Journal of Pharmacology. 469 (1–3): 1–12. doi:10.1016/S0014-2999(03)01723-0. PMID 12782179.
  • Su TP, Hayashi T (October 2003). "Understanding the molecular mechanism of sigma-1 receptors: towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction". Current Medicinal Chemistry. 10 (20): 2073–2080. doi:10.2174/0929867033456783. PMID 12871086.
  • Nguyen EC, McCracken KA, Liu Y, Pouw B, Matsumoto RR (October 2005). "Involvement of sigma (sigma) receptors in the acute actions of methamphetamine: receptor binding and behavioral studies". Neuropharmacology. 49 (5): 638–645. doi:10.1016/j.neuropharm.2005.04.016. PMID 15939443. S2CID 41068558.
  • Wang J, Mack AL, Coop A, Matsumoto RR (November 2007). "Novel sigma (sigma) receptor agonists produce antidepressant-like effects in mice". European Neuropsychopharmacology. 17 (11): 708–716. doi:10.1016/j.euroneuro.2007.02.007. PMC 4041597. PMID 17376658.
  • Petukhov PA, Zhang J, Kozikowski AP, Wang CZ, Ye YP, Johnson KM, Tella SR (July 2002). "SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement". Journal of Medicinal Chemistry. 45 (15): 3161–3170. doi:10.1021/jm0200153. PMID 12109901.
  • Froimowitz M, Gu Y, Dakin LA, Nagafuji PM, Kelley CJ, Parrish D, et al. (January 2007). "Slow-onset, long-duration, alkyl analogues of methylphenidate with enhanced selectivity for the dopamine transporter". Journal of Medicinal Chemistry. 50 (2): 219–232. doi:10.1021/jm0608614. PMID 17228864.
  • Wang S, Sakamuri S, Enyedy IJ, Kozikowski AP, Deschaux O, Bandyopadhyay BC, et al. (February 2000). "Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationships, and behavioral pharmacological studies". Journal of Medicinal Chemistry. 43 (3): 351–360. doi:10.1021/jm990516x. PMID 10669562.
  • Chiamulera C, Epping-Jordan MP, Zocchi A, Marcon C, Cottiny C, Tacconi S, et al. (September 2001). "Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice". Nature Neuroscience. 4 (9): 873–874. doi:10.1038/nn0901-873. PMID 11528416. S2CID 1314227.
  • Petukhov PA, Zhang J, Wang CZ, Ye YP, Johnson KM, Kozikowski AP (June 2004). "Synthesis, molecular modeling, and biological studies of novel piperidine-based analogues of cocaine: evidence of unfavorable interactions proximal to the 3alpha-position of the piperidine ring". Journal of Medicinal Chemistry. 47 (12): 3009–3018. doi:10.1021/jm0303296. PMID 15163183.
  • Yuan H, Kozikowski AP, Petukhov PA (December 2004). "CoMFA study of piperidine analogues of cocaine at the dopamine transporter: exploring the binding mode of the 3 alpha-substituent of the piperidine ring using pharmacophore-based flexible alignment". Journal of Medicinal Chemistry. 47 (25): 6137–6143. doi:10.1021/jm049544s. PMID 15566285.
  • Lieske SF, Yang B, Eldefrawi ME, MacKerell AD, Wright J (March 1998). "(-)-3 beta-Substituted ecgonine methyl esters as inhibitors for cocaine binding and dopamine uptake". Journal of Medicinal Chemistry. 41 (6): 864–876. doi:10.1021/jm970025h. PMID 9526561.
  • Petukhov PA, Zhang M, Johnson KJ, Tella SR, Kozikowski AP (August 2001). "Sar studies of piperidine-based analogues of cocaine. Part 3: oxadiazoles". Bioorganic & Medicinal Chemistry Letters. 11 (16): 2079–2083. doi:10.1016/S0960-894X(01)00379-1. PMID 11514143.
  • Tamiz AP, Bandyopadhyay BC, Zhang J, Flippen-Anderson JL, Zhang M, Wang CZ, et al. (May 2001). "Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors". Journal of Medicinal Chemistry. 44 (10): 1615–1622. doi:10.1021/jm000552s. PMID 11334571.
  • Amat M, Bosch J, Hidalgo J, Cantó M, Pérez M, Llor N, et al. (May 2000). "Synthesis of enantiopure trans-3,4-disubstituted piperidines. An enantiodivergent synthesis of (+)- and (-)-paroxetine". The Journal of Organic Chemistry. 65 (10): 3074–3084. doi:10.1021/jo991816p. PMID 10814199.
  • Johnson TA, Jang DO, Slafer BW, Curtis MD, Beak P (October 2002). "Asymmetric carbon-carbon bond formations in conjugate additions of lithiated N-Boc allylic and benzylic amines to nitroalkenes: enantioselective synthesis of substituted piperidines, pyrrolidines, and pyrimidinones". Journal of the American Chemical Society. 124 (39): 11689–11698. doi:10.1021/ja0271375. PMID 12296735.
  • Tamiz AP, Zhang J, Flippen-Anderson JL, Zhang M, Johnson KM, Deschaux O, et al. (March 2000). "Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors". Journal of Medicinal Chemistry. 43 (6): 1215–1222. doi:10.1021/jm9905561. PMID 10737754.
  • Zhou J, He R, Johnson KM, Ye Y, Kozikowski AP (November 2004). "Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization". Journal of Medicinal Chemistry. 47 (24): 5821–5824. doi:10.1021/jm040117o. PMC 1395211. PMID 15537337.
  • He R, Kurome T, Giberson KM, Johnson KM, Kozikowski AP (December 2005). "Further structure-activity relationship studies of piperidine-based monoamine transporter inhibitors: effects of piperidine ring stereochemistry on potency. Identification of norepinephrine transporter selective ligands and broad-spectrum transporter inhibitors". Journal of Medicinal Chemistry. 48 (25): 7970–7979. doi:10.1021/jm050694s. PMID 16335921.
  • Musachio JL, Hong J, Ichise M, Seneca N, Brown AK, Liow JS, et al. (June 2006). "Development of new brain imaging agents based upon nocaine-modafinil hybrid monoamine transporter inhibitors". Bioorganic & Medicinal Chemistry Letters. 16 (12): 3101–3104. doi:10.1016/j.bmcl.2006.03.066. PMID 16621532.
  • Zhou J (December 2004). "Norepinephrine transporter inhibitors and their therapeutic potential". Drugs of the Future. 29 (12): 1235–1244. doi:10.1358/dof.2004.029.12.855246. PMC 1518795. PMID 16871320.
  • Yuan H, Petukhov PA (December 2006). "Improved 3D-QSAR CoMFA of the dopamine transporter blockers with multiple conformations using the genetic algorithm". Bioorganic & Medicinal Chemistry Letters. 16 (24): 6267–6272. doi:10.1016/j.bmcl.2006.09.037. PMID 17027270.

ncbi.nlm.nih.gov

organic-chemistry.org

semanticscholar.org

api.semanticscholar.org

  • Provencher BA, Eshleman AJ, Johnson RA, Shi X, Kryatova O, Nelson J, et al. (October 2018). "Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter". Journal of Medicinal Chemistry. 61 (20): 9121–9131. doi:10.1021/acs.jmedchem.8b00542. PMID 30240563. S2CID 52312790.
  • Shao L, Li W, Xie Q, Yin H (February 2014). "Triple reuptake inhibitors: a patent review (2006 - 2012)". Expert Opinion on Therapeutic Patents. 24 (2): 131–154. doi:10.1517/13543776.2014.859676. PMID 24289044. S2CID 1825304.
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