4-HO-DPT (English Wikipedia)

Malaca S, Lo Faro AF, Tamborra A, Pichini S, Busardò FP, Huestis MA (December 2020). "Toxicology and Analysis of Psychoactive Tryptamines". International Journal of Molecular Sciences. 21 (23): 9279. doi:10.3390/ijms21239279. PMC 7730282. PMID 33291798. 4-OH-DPT is the 4-hydroxylated DPT derivative first synthesized by Shulgin et al. [82]. 4-OH-DPT is a light beige or white powder [54] that acts as a 5-HT2A partial agonist. 4-OH-DPT also shares structural similarity with psilocin [83]. Effects are dose dependent, with onset at 15–45 min and duration of 5–8 h. According to user reports, synthetic 4-OH-DPT produces visual effects and hallucinatory states [84].
Klein AK, Chatha M, Laskowski LJ, Anderson EI, Brandt SD, Chapman SJ, et al. (April 2021). "Investigation of the Structure-Activity Relationships of Psilocybin Analogues". ACS Pharmacology & Translational Science. 4 (2): 533–542. doi:10.1021/acsptsci.0c00176. PMC 8033608. PMID 33860183. Repke synthesized several other psilocin homologues, including 4-hydroxy-N-methyl-N-ethyltryptamine (4-HO-MET), 4-hydroxy-N-methyl-N-isopropyltryptamine (4-HO-MIPT), 4-hydroxy-N,N-dipropyltryptamine (4-HO-DPT), and 4-hydroxy-N,N-diisopropyltryptamine (4-HO-DIPT).63,64
Repke DB, Ferguson WJ, Bates DK (1977). "Psilocin analogs. 1. Synthesis of 3-[2-(dialkylamino)ethyl] -and 3-[2-(cycloalkylamino)ethyl] indol-4-ols". Journal of Heterocyclic Chemistry. 14 (1): 71–74. doi:10.1002/jhet.5570140113. ISSN 0022-152X.
Ferguson WJ, Bates DK, Repke DB (1977). "Psilocin analogs. 1. Synthesis of 3-[2-(dialkylamino)ethyl] -and 3-[2-(cycloalkylamino)ethyl] indol-4-ols". Journal of Heterocyclic Chemistry. 14 (1): 71–74. doi:10.1002/jhet.5570140113. ISSN 0022-152X.
Palamar JJ, Acosta P (January 2020). "A qualitative descriptive analysis of effects of psychedelic phenethylamines and tryptamines". Human Psychopharmacology. 35 (1) e2719. doi:10.1002/hup.2719. PMC 6995261. PMID 31909513.
Tanaka R, Kawamura M, Hakamatsuka T, Kikura-Hanajiri R (2021). "Identification of six tryptamine derivatives as designer drugs in illegal products". Forensic Toxicology. 39 (1): 248–258. doi:10.1007/s11419-020-00556-5. ISSN 1860-8965. Retrieved 16 October 2025.
Berardinelli D, Montanari E, Malaca S, Zaami S, Busardò FP, Huestis MA, et al. (2022). "4-Hydroxy-N,N-methylpropyltryptamine (4-OH-MPT) in vitro human metabolism". Toxicologie Analytique et Clinique. 34 (3): S96. Bibcode:2022ToxAC..34Q..96B. doi:10.1016/j.toxac.2022.06.147.
Carlier J, Malaca S, Huestis MA, Tagliabracci A, Tini A, Busardò FP (December 2022). "Biomarkers of 4-hydroxy-N,N-methylpropyltryptamine (4-OH-MPT) intake identified from human hepatocyte incubations". Expert Opinion on Drug Metabolism & Toxicology. 18 (12): 831–840. doi:10.1080/17425255.2022.2166826. PMID 36609205.
Chadeayne AR, Pham DN, Golen JA, Manke DR (2019-11-28). "Bis(4-hydroxy-N,N-di-n-propyltryptammonium) fumarate tetrahydrate". IUCrData. 4 (11) x191469. Bibcode:2019IUCrD...491469C. doi:10.1107/S241431461901469X. ISSN 2414-3146.

erowid.org (Global: 3,887^th place; English: 3,197^th place)

Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252. "4-HO-DPT".

europa.eu (Global: 68^th place; English: 117^th place)

euda.europa.eu

"EMCDDA–Europol 2012 Annual Report on the implementation of Council Decision 2005/387/JHA (New drugs in Europe, 2012)". www.euda.europa.eu. 2 July 2024. Retrieved 9 October 2025.

folkhalsomyndigheten.se (Global: low place; English: low place)

"Tio nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten [Public Health Agency of Sweden]. February 14, 2018. Retrieved August 24, 2020.

gesetze-im-internet.de (Global: 1,249^th place; English: 4,347^th place)

"§ 4 NpSG" (in German). Bundesamt für Justiz [Federal Office of Justice]. Retrieved December 10, 2019.
"§ 3 NpSG" (in German). Bundesamt für Justiz [Federal Office of Justice]. Retrieved December 10, 2019.

harvard.edu (Global: 18^th place; English: 17^th place)

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Berardinelli D, Montanari E, Malaca S, Zaami S, Busardò FP, Huestis MA, et al. (2022). "4-Hydroxy-N,N-methylpropyltryptamine (4-OH-MPT) in vitro human metabolism". Toxicologie Analytique et Clinique. 34 (3): S96. Bibcode:2022ToxAC..34Q..96B. doi:10.1016/j.toxac.2022.06.147.
Chadeayne AR, Pham DN, Golen JA, Manke DR (2019-11-28). "Bis(4-hydroxy-N,N-di-n-propyltryptammonium) fumarate tetrahydrate". IUCrData. 4 (11) x191469. Bibcode:2019IUCrD...491469C. doi:10.1107/S241431461901469X. ISSN 2414-3146.

iucr.org (Global: low place; English: 9,593^rd place)

scripts.iucr.org

Chadeayne AR, Pham DN, Golen JA, Manke DR (2019-11-28). "Bis(4-hydroxy-N,N-di-n-propyltryptammonium) fumarate tetrahydrate". IUCrData. 4 (11) x191469. Bibcode:2019IUCrD...491469C. doi:10.1107/S241431461901469X. ISSN 2414-3146.

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laws-lois.justice.gc.ca

"Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.

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"Schedule 2: Part I: Class A Drugs". Misuse of Drugs Act 1971. UK Government. Retrieved August 20, 2020.

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pubmed.ncbi.nlm.nih.gov

Malaca S, Lo Faro AF, Tamborra A, Pichini S, Busardò FP, Huestis MA (December 2020). "Toxicology and Analysis of Psychoactive Tryptamines". International Journal of Molecular Sciences. 21 (23): 9279. doi:10.3390/ijms21239279. PMC 7730282. PMID 33291798. 4-OH-DPT is the 4-hydroxylated DPT derivative first synthesized by Shulgin et al. [82]. 4-OH-DPT is a light beige or white powder [54] that acts as a 5-HT2A partial agonist. 4-OH-DPT also shares structural similarity with psilocin [83]. Effects are dose dependent, with onset at 15–45 min and duration of 5–8 h. According to user reports, synthetic 4-OH-DPT produces visual effects and hallucinatory states [84].
Klein AK, Chatha M, Laskowski LJ, Anderson EI, Brandt SD, Chapman SJ, et al. (April 2021). "Investigation of the Structure-Activity Relationships of Psilocybin Analogues". ACS Pharmacology & Translational Science. 4 (2): 533–542. doi:10.1021/acsptsci.0c00176. PMC 8033608. PMID 33860183. Repke synthesized several other psilocin homologues, including 4-hydroxy-N-methyl-N-ethyltryptamine (4-HO-MET), 4-hydroxy-N-methyl-N-isopropyltryptamine (4-HO-MIPT), 4-hydroxy-N,N-dipropyltryptamine (4-HO-DPT), and 4-hydroxy-N,N-diisopropyltryptamine (4-HO-DIPT).63,64
Palamar JJ, Acosta P (January 2020). "A qualitative descriptive analysis of effects of psychedelic phenethylamines and tryptamines". Human Psychopharmacology. 35 (1) e2719. doi:10.1002/hup.2719. PMC 6995261. PMID 31909513.
Carlier J, Malaca S, Huestis MA, Tagliabracci A, Tini A, Busardò FP (December 2022). "Biomarkers of 4-hydroxy-N,N-methylpropyltryptamine (4-OH-MPT) intake identified from human hepatocyte incubations". Expert Opinion on Drug Metabolism & Toxicology. 18 (12): 831–840. doi:10.1080/17425255.2022.2166826. PMID 36609205.

ncbi.nlm.nih.gov

Malaca S, Lo Faro AF, Tamborra A, Pichini S, Busardò FP, Huestis MA (December 2020). "Toxicology and Analysis of Psychoactive Tryptamines". International Journal of Molecular Sciences. 21 (23): 9279. doi:10.3390/ijms21239279. PMC 7730282. PMID 33291798. 4-OH-DPT is the 4-hydroxylated DPT derivative first synthesized by Shulgin et al. [82]. 4-OH-DPT is a light beige or white powder [54] that acts as a 5-HT2A partial agonist. 4-OH-DPT also shares structural similarity with psilocin [83]. Effects are dose dependent, with onset at 15–45 min and duration of 5–8 h. According to user reports, synthetic 4-OH-DPT produces visual effects and hallucinatory states [84].
Klein AK, Chatha M, Laskowski LJ, Anderson EI, Brandt SD, Chapman SJ, et al. (April 2021). "Investigation of the Structure-Activity Relationships of Psilocybin Analogues". ACS Pharmacology & Translational Science. 4 (2): 533–542. doi:10.1021/acsptsci.0c00176. PMC 8033608. PMID 33860183. Repke synthesized several other psilocin homologues, including 4-hydroxy-N-methyl-N-ethyltryptamine (4-HO-MET), 4-hydroxy-N-methyl-N-isopropyltryptamine (4-HO-MIPT), 4-hydroxy-N,N-dipropyltryptamine (4-HO-DPT), and 4-hydroxy-N,N-diisopropyltryptamine (4-HO-DIPT).63,64
Palamar JJ, Acosta P (January 2020). "A qualitative descriptive analysis of effects of psychedelic phenethylamines and tryptamines". Human Psychopharmacology. 35 (1) e2719. doi:10.1002/hup.2719. PMC 6995261. PMID 31909513.

psychedelicreview.com (Global: low place; English: low place)

Bauer BE (2 January 2020). "Scientists Solve the Crystal Structure of the Psilocbyin Derviative 4-HO-DPT". Psychedelic Science Review. Retrieved 8 October 2025.

springer.com (Global: 274^th place; English: 309^th place)

link.springer.com

Tanaka R, Kawamura M, Hakamatsuka T, Kikura-Hanajiri R (2021). "Identification of six tryptamine derivatives as designer drugs in illegal products". Forensic Toxicology. 39 (1): 248–258. doi:10.1007/s11419-020-00556-5. ISSN 1860-8965. Retrieved 16 October 2025.

web.archive.org (Global: 1^st place; English: 1^st place)

Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4.

worldcat.org (Global: 5^th place; English: 5^th place)

search.worldcat.org

Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252. "4-HO-DPT".
Repke DB, Ferguson WJ, Bates DK (1977). "Psilocin analogs. 1. Synthesis of 3-[2-(dialkylamino)ethyl] -and 3-[2-(cycloalkylamino)ethyl] indol-4-ols". Journal of Heterocyclic Chemistry. 14 (1): 71–74. doi:10.1002/jhet.5570140113. ISSN 0022-152X.
Ferguson WJ, Bates DK, Repke DB (1977). "Psilocin analogs. 1. Synthesis of 3-[2-(dialkylamino)ethyl] -and 3-[2-(cycloalkylamino)ethyl] indol-4-ols". Journal of Heterocyclic Chemistry. 14 (1): 71–74. doi:10.1002/jhet.5570140113. ISSN 0022-152X.
Tanaka R, Kawamura M, Hakamatsuka T, Kikura-Hanajiri R (2021). "Identification of six tryptamine derivatives as designer drugs in illegal products". Forensic Toxicology. 39 (1): 248–258. doi:10.1007/s11419-020-00556-5. ISSN 1860-8965. Retrieved 16 October 2025.
Chadeayne AR, Pham DN, Golen JA, Manke DR (2019-11-28). "Bis(4-hydroxy-N,N-di-n-propyltryptammonium) fumarate tetrahydrate". IUCrData. 4 (11) x191469. Bibcode:2019IUCrD...491469C. doi:10.1107/S241431461901469X. ISSN 2414-3146.
"Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes" (PDF). Bundesgesetzblatt Jahrgang 2019 Teil I Nr. 27 (in German). Bundesanzeiger Verlag. July 17, 2019. pp. 1083–1094. ISSN 0341-1095.

4-HO-DPT (English Wikipedia)

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