Adeno-associated virus (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Adeno-associated virus" in English language version.

refsWebsite

Global rank English rank

165nih.gov

4^th place

100doi.org

2^nd place

12harvard.edu

18^th place

17^th place

8semanticscholar.org

11^th place

8^th place

7fda.gov

447^th place

338^th place

4web.archive.org

1^st place

1nature.com

234^th place

397^th place

1abedia.com

low place

1psu.edu

207^th place

136^th place

1avexis.com

low place

1vectorbuilder.com

low place

1ictv.global

7,012^th place

4,406^th place

1cnn.com

28^th place

26^th place

1sciencedaily.com

993^rd place

920^th place

1zenodo.org

621^st place

380^th place

1addgene.org

low place

1aacrjournals.org

8,869^th place

8,487^th place

1vectorbiolabs.com

low place

1uiowa.edu

3,018^th place

1,865^th place

aacrjournals.org

cancerres.aacrjournals.org

Yalkinoglu AO, Heilbronn R, Bürkle A, Schlehofer JR, zur Hausen H (June 1988). "DNA amplification of adeno-associated virus as a response to cellular genotoxic stress". Cancer Research. 48 (11): 3123–9. PMID 2835153.

abedia.com

"Vectors used in Gene Therapy Clinical Trials". Journal of Gene Medicine. Wiley. December 2018. Archived from the original on 21 October 2019. Retrieved 4 January 2012.

addgene.org

"Adeno-associated Virus (AAV) Guide". Addgene. Watertown, MA.

avexis.com

investors.avexis.com

"AveXis Reports Data from Ongoing Phase 1 Trial of AVXS-101 in Spinal Muscular Atrophy Type 1". Avexis. 6 May 2016. Archived from the original on 11 June 2017. Retrieved 8 May 2016.

cnn.com

"Common virus 'kills cancer'". CNN. 22 June 2005. Retrieved 5 August 2009.

doi.org

Naso MF, Tomkowicz B, Perry WL, Strohl WR (August 2017). "Adeno-Associated Virus (AAV) as a Vector for Gene Therapy". BioDrugs. 31 (4): 317–334. doi:10.1007/s40259-017-0234-5. PMC 5548848. PMID 28669112.
Wu Z, Yang H, Colosi P (January 2010). "Effect of genome size on AAV vector packaging". Molecular Therapy. 18 (1): 80–86. doi:10.1038/mt.2009.255. PMC 2839202. PMID 19904234.
Grieger JC, Samulski RJ (2005). "Adeno-associated Virus as a Gene Therapy Vector: Vector Development, Production and Clinical Applications". Adeno-associated virus as a gene therapy vector: vector development, production and clinical applications. Advances in Biochemical Engineering/Biotechnology. Vol. 99. pp. 119–45. doi:10.1007/10_005. ISBN 978-3-540-28404-8. PMID 16568890.
Maguire AM, Simonelli F, Pierce EA, Pugh EN, Mingozzi F, Bennicelli J, et al. (May 2008). "Safety and efficacy of gene transfer for Leber's congenital amaurosis". The New England Journal of Medicine. 358 (21): 2240–8. doi:10.1056/NEJMoa0802315. PMC 2829748. PMID 18441370.
Tacke F (May 2023). "Severe hepatitis outbreak in children linked to AAV2 virus". Nature. 617 (7961): 471–472. Bibcode:2023Natur.617..471T. doi:10.1038/d41586-023-00570-8. PMID 36997704.
Servellita V, Sotomayor Gonzalez A, Lamson DM, Foresythe A, Huh HJ, Bazinet AL, et al. (May 2023). "Adeno-associated virus type 2 in US children with acute severe hepatitis". Nature. 617 (7961): 574–580. Bibcode:2023Natur.617..574S. doi:10.1038/s41586-023-05949-1. PMC 10170441. PMID 36996871.
Carter BJ (December 2004). "Adeno-associated virus and the development of adeno-associated virus vectors: a historical perspective". Molecular Therapy. 10 (6): 981–9. doi:10.1016/j.ymthe.2004.09.011. PMID 15564130.
Kotin RM, Siniscalco M, Samulski RJ, Zhu XD, Hunter L, Laughlin CA, et al. (March 1990). "Site-specific integration by adeno-associated virus". Proceedings of the National Academy of Sciences of the United States of America. 87 (6): 2211–5. Bibcode:1990PNAS...87.2211K. doi:10.1073/pnas.87.6.2211. PMC 53656. PMID 2156265.
Surosky RT, Urabe M, Godwin SG, McQuiston SA, Kurtzman GJ, Ozawa K, et al. (October 1997). "Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome". Journal of Virology. 71 (10): 7951–9. doi:10.1128/JVI.71.10.7951-7959.1997. PMC 192153. PMID 9311886.
Daya S, Berns KI (October 2008). "Gene therapy using adeno-associated virus vectors". Clinical Microbiology Reviews. 21 (4): 583–93. doi:10.1128/CMR.00008-08. PMC 2570152. PMID 18854481.
Chirmule N, Propert K, Magosin S, Qian Y, Qian R, Wilson J (September 1999). "Immune responses to adenovirus and adeno-associated virus in humans". Gene Therapy. 6 (9): 1574–83. doi:10.1038/sj.gt.3300994. PMID 10490767.
Hernandez YJ, Wang J, Kearns WG, Loiler S, Poirier A, Flotte TR (October 1999). "Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model". Journal of Virology. 73 (10): 8549–58. doi:10.1128/JVI.73.10.8549-8558.1999. PMC 112875. PMID 10482608.
Ponnazhagan S, Mukherjee P, Yoder MC, Wang XS, Zhou SZ, Kaplan J, et al. (April 1997). "Adeno-associated virus 2-mediated gene transfer in vivo: organ-tropism and expression of transduced sequences in mice". Gene. 190 (1): 203–10. doi:10.1016/S0378-1119(96)00576-8. PMID 9185868.
Ghosh, A., Yue, Y., Lai, Y., Duan, D. (2008). "A Hybrid Vector System Expands Adeno-associated Viral Vector Packaging Capacity in a Transgene- Independent manner" (PDF). Molecular Therapy. 16 (1): 124–130. doi:10.1038/sj.mt.6300322. PMID 17984978.{{cite journal}}: CS1 maint: overridden setting (link)
Bak RO, Porteus MH (July 2017). "CRISPR-Mediated Integration of Large Gene Cassettes Using AAV Donor Vectors". Cell Reports. 20 (3): 750–756. doi:10.1016/j.celrep.2017.06.064. PMC 5568673. PMID 28723575.
McCarty DM, Monahan PE, Samulski RJ (August 2001). "Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis". Gene Therapy. 8 (16): 1248–54. doi:10.1038/sj.gt.3301514. PMID 11509958.
Rogers GL, Martino AT, Zolotukhin I, Ertl HC, Herzog RW (January 2014). "Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B". Journal of Translational Medicine. 12: 25. doi:10.1186/1479-5876-12-25. PMC 3904690. PMID 24460861.
Bainbridge JW, Smith AJ, Barker SS, Robbie S, Henderson R, Balaggan K, et al. (May 2008). "Effect of gene therapy on visual function in Leber's congenital amaurosis". The New England Journal of Medicine. 358 (21): 2231–9. CiteSeerX 10.1.1.574.4003. doi:10.1056/NEJMoa0802268. PMID 18441371.
Hauswirth WW, Aleman TS, Kaushal S, Cideciyan AV, Schwartz SB, Wang L, et al. (October 2008). "Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial". Human Gene Therapy. 19 (10): 979–90. doi:10.1089/hum.2008.107. PMC 2940541. PMID 18774912.
Nathwani AC, Tuddenham EG, Rangarajan S, Rosales C, McIntosh J, Linch DC, et al. (December 2011). "Adenovirus-associated virus vector-mediated gene transfer in hemophilia B". The New England Journal of Medicine. 365 (25): 2357–65. doi:10.1056/NEJMoa1108046. PMC 3265081. PMID 22149959.
Jessup M, Greenberg B, Mancini D, Cappola T, Pauly DF, Jaski B, et al. (July 2011). "Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure". Circulation. 124 (3): 304–13. doi:10.1161/CIRCULATIONAHA.111.022889. PMC 5843948. PMID 21709064.
Gaudet D, Méthot J, Déry S, Brisson D, Essiembre C, Tremblay G, et al. (April 2013). "Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial". Gene Ther. 20 (4): 361–9. doi:10.1038/gt.2012.43. PMC 4956470. PMID 22717743.
LeWitt PA, Rezai AR, Leehey MA, Ojemann SG, Flaherty AW, Eskandar EN, et al. (April 2011). "AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial". The Lancet. Neurology. 10 (4): 309–19. doi:10.1016/S1474-4422(11)70039-4. PMID 21419704. S2CID 37154043.
Carter BJ (May 2005). "Adeno-associated virus vectors in clinical trials". Human Gene Therapy. 16 (5): 541–50. doi:10.1089/hum.2005.16.541. PMID 15916479.
Kaplitt MG, Feigin A, Tang C, Fitzsimons HL, Mattis P, Lawlor PA, et al. (June 2007). "Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial". Lancet. 369 (9579): 2097–105. doi:10.1016/S0140-6736(07)60982-9. PMID 17586305. S2CID 24491886.
Bohenzky RA, LeFebvre RB, Berns KI (October 1988). "Sequence and symmetry requirements within the internal palindromic sequences of the adeno-associated virus terminal repeat". Virology. 166 (2): 316–27. doi:10.1016/0042-6822(88)90502-8. PMID 2845646.
Wang XS, Ponnazhagan S, Srivastava A (July 1995). "Rescue and replication signals of the adeno-associated virus 2 genome". Journal of Molecular Biology. 250 (5): 573–80. doi:10.1006/jmbi.1995.0398. PMID 7623375.
Weitzman MD, Kyöstiö SR, Kotin RM, Owens RA (June 1994). "Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA". Proceedings of the National Academy of Sciences of the United States of America. 91 (13): 5808–12. Bibcode:1994PNAS...91.5808W. doi:10.1073/pnas.91.13.5808. PMC 44086. PMID 8016070.
Zhou X, Muzyczka N (April 1998). "In vitro packaging of adeno-associated virus DNA". Journal of Virology. 72 (4): 3241–7. doi:10.1128/JVI.72.4.3241-3247.1998. PMC 109794. PMID 9525651.
Nony P, Tessier J, Chadeuf G, Ward P, Giraud A, Dugast M, et al. (October 2001). "Novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences". Journal of Virology. 75 (20): 9991–4. doi:10.1128/JVI.75.20.9991-9994.2001. PMC 114572. PMID 11559833.
Nony P, Chadeuf G, Tessier J, Moullier P, Salvetti A (January 2003). "Evidence for packaging of rep-cap sequences into adeno-associated virus (AAV) type 2 capsids in the absence of inverted terminal repeats: a model for generation of rep-positive AAV particles". Journal of Virology. 77 (1): 776–81. doi:10.1128/JVI.77.1.776-781.2003. PMC 140600. PMID 12477885.
Philpott NJ, Giraud-Wali C, Dupuis C, Gomos J, Hamilton H, Berns KI, et al. (June 2002). "Efficient integration of recombinant adeno-associated virus DNA vectors requires a p5-rep sequence in cis". Journal of Virology. 76 (11): 5411–21. doi:10.1128/JVI.76.11.5411-5421.2002. PMC 137060. PMID 11991970.
Tullis GE, Shenk T (December 2000). "Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal size". Journal of Virology. 74 (24): 11511–21. doi:10.1128/JVI.74.24.11511-11521.2000. PMC 112431. PMID 11090148.
Kyöstiö SR, Owens RA, Weitzman MD, Antoni BA, Chejanovsky N, Carter BJ (May 1994). "Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levels". Journal of Virology. 68 (5): 2947–57. doi:10.1128/JVI.68.5.2947-2957.1994. PMC 236783. PMID 8151765.
Im DS, Muzyczka N (May 1990). "The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity". Cell. 61 (3): 447–57. doi:10.1016/0092-8674(90)90526-K. PMID 2159383. S2CID 27997617.
Im DS, Muzyczka N (February 1992). "Partial purification of adeno-associated virus Rep78, Rep52, and Rep40 and their biochemical characterization". Journal of Virology. 66 (2): 1119–28. doi:10.1128/JVI.66.2.1119-1128.1992. PMC 240816. PMID 1309894.
Samulski RJ (2003). "AAV Vectors, the Future Workhorse of Human Gene Therapy". Ernst Schering Research Foundation Workshop. Human Gene Therapy: Current Opportunities and Future Trends. pp. 25–40. doi:10.1007/978-3-662-05352-2_3. ISBN 978-3-662-05354-6. PMID 12894449.
Trempe JP, Carter BJ (January 1988). "Regulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translation". Journal of Virology. 62 (1): 68–74. doi:10.1128/JVI.62.1.68-74.1988. PMC 250502. PMID 2824856.
Jay FT, Laughlin CA, Carter BJ (May 1981). "Eukaryotic translational control: adeno-associated virus protein synthesis is affected by a mutation in the adenovirus DNA-binding protein". Proceedings of the National Academy of Sciences of the United States of America. 78 (5): 2927–31. Bibcode:1981PNAS...78.2927J. doi:10.1073/pnas.78.5.2927. PMC 319472. PMID 6265925.
Sonntag F, Schmidt K, Kleinschmidt JA (June 2010). "A viral assembly factor promotes AAV2 capsid formation in the nucleolus". Proceedings of the National Academy of Sciences of the United States of America. 107 (22): 10220–5. Bibcode:2010PNAS..10710220S. doi:10.1073/pnas.1001673107. PMC 2890453. PMID 20479244.
Pierson EE, Keifer DZ, Asokan A, Jarrold MF (July 2016). "Resolving Adeno-Associated Viral Particle Diversity With Charge Detection Mass Spectrometry". Analytical Chemistry. 88 (13). American Chemical Society (ACS): 6718–6725. doi:10.1021/acs.analchem.6b00883. PMC 6537880. PMID 27310298.
Xie Q, Bu W, Bhatia S, Hare J, Somasundaram T, Azzi A, et al. (August 2002). "The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy". Proceedings of the National Academy of Sciences of the United States of America. 99 (16): 10405–10. Bibcode:2002PNAS...9910405X. doi:10.1073/pnas.162250899. PMC 124927. PMID 12136130.
Sonntag F, Köther K, Schmidt K, Weghofer M, Raupp C, Nieto K, et al. (December 2011). "The assembly-activating protein promotes capsid assembly of different adeno-associated virus serotypes". Journal of Virology. 85 (23): 12686–97. doi:10.1128/JVI.05359-11. PMC 3209379. PMID 21917944.
Becerra SP, Rose JA, Hardy M, Baroudy BM, Anderson CW (December 1985). "Direct mapping of adeno-associated virus capsid proteins B and C: a possible ACG initiation codon". Proceedings of the National Academy of Sciences of the United States of America. 82 (23): 7919–23. Bibcode:1985PNAS...82.7919B. doi:10.1073/pnas.82.23.7919. PMC 390881. PMID 2999784.
Cassinotti P, Weitz M, Tratschin JD (November 1988). "Organization of the adeno-associated virus (AAV) capsid gene: mapping of a minor spliced mRNA coding for virus capsid protein 1". Virology. 167 (1): 176–84. doi:10.1016/0042-6822(88)90067-0. PMID 2847413.
Muralidhar S, Becerra SP, Rose JA (January 1994). "Site-directed mutagenesis of adeno-associated virus type 2 structural protein initiation codons: effects on regulation of synthesis and biological activity". Journal of Virology. 68 (1): 170–6. doi:10.1128/JVI.68.1.170-176.1994. PMC 236275. PMID 8254726.
Trempe JP, Carter BJ (September 1988). "Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein". Journal of Virology. 62 (9): 3356–63. doi:10.1128/JVI.62.9.3356-3363.1988. PMC 253458. PMID 2841488.
Rabinowitz JE, Samulski RJ (December 2000). "Building a better vector: the manipulation of AAV virions". Virology. 278 (2): 301–8. doi:10.1006/viro.2000.0707. PMID 11118354.
Girod A, Wobus CE, Zádori Z, Ried M, Leike K, Tijssen P, et al. (May 2002). "The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity". The Journal of General Virology. 83 (Pt 5): 973–8. doi:10.1099/0022-1317-83-5-973. PMID 11961250.
Warrington KH, Gorbatyuk OS, Harrison JK, Opie SR, Zolotukhin S, Muzyczka N (June 2004). "Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus". Journal of Virology. 78 (12): 6595–609. doi:10.1128/JVI.78.12.6595-6609.2004. PMC 416546. PMID 15163751.
Rumachik NG, Malaker SA, Poweleit N, Maynard LH, Adams CM, Leib RD, et al. (May 2020). "Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors". Molecular Therapy – Methods & Clinical Development. 18: 98–118. doi:10.1016/j.omtm.2020.05.018. PMC 7488757. PMID 32995354.
Chen Q, Njenga R, Leuchs B, Chiocca S, Kleinschmidt J, Muller M (September 2020). "SUMOylation Targets Adeno-associated Virus Capsids but Mainly Restricts Transduction by Cellular Mechanisms". Journal of Virology. 94 (19): e00871-20. doi:10.1128/JVI.00871-20. PMC 7495375. PMID 32669341.
Giles AR, Sims JJ, Turner KB, Govindasamy L, Alvira MR, Lock M, et al. (December 2018). "Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function". Molecular Therapy. 26 (12): 2848–2862. doi:10.1016/j.ymthe.2018.09.013. PMC 6277538. PMID 30343890.
Mori S, Wang L, Takeuchi T, Kanda T (December 2004). "Two novel adeno-associated viruses from cynomolgus monkey: pseudotyping characterization of capsid protein". Virology. 330 (2): 375–83. doi:10.1016/j.virol.2004.10.012. PMID 15567432.
Issa SS, Shaimardanova AA, Solovyeva VV, Rizvanov AA (1 March 2023). "Various AAV Serotypes and Their Applications in Gene Therapy: An Overview". Cells. 12 (5): 785. doi:10.3390/cells12050785. PMC 10000783. PMID 36899921.
Bartlett JS, Samulski RJ, McCown TJ (May 1998). "Selective and rapid uptake of adeno-associated virus type 2 in brain". Human Gene Therapy. 9 (8): 1181–6. doi:10.1089/hum.1998.9.8-1181. PMID 9625257.
Fischer AC, Beck SE, Smith CI, Laube BL, Askin FB, Guggino SE, et al. (December 2003). "Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques". Molecular Therapy. 8 (6): 918–26. doi:10.1016/j.ymthe.2003.08.015. PMID 14664794.
Nicklin SA, Buening H, Dishart KL, de Alwis M, Girod A, Hacker U, et al. (September 2001). "Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells". Molecular Therapy. 4 (3): 174–81. doi:10.1006/mthe.2001.0424. PMID 11545607.
Rabinowitz JE, Xiao W, Samulski RJ (December 1999). "Insertional mutagenesis of AAV2 capsid and the production of recombinant virus". Virology. 265 (2): 274–85. doi:10.1006/viro.1999.0045. PMID 10600599.
Shi W, Bartlett JS (April 2003). "RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism". Molecular Therapy. 7 (4): 515–25. doi:10.1016/S1525-0016(03)00042-X. PMID 12727115.
Wu P, Xiao W, Conlon T, Hughes J, Agbandje-McKenna M, Ferkol T, et al. (September 2000). "Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism". Journal of Virology. 74 (18): 8635–47. doi:10.1128/JVI.74.18.8635-8647.2000. PMC 102071. PMID 10954565.
Manno CS, Chew AJ, Hutchison S, Larson PJ, Herzog RW, Arruda VR, et al. (April 2003). "AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B". Blood. 101 (8): 2963–72. doi:10.1182/blood-2002-10-3296. PMID 12515715.
Richter M, Iwata A, Nyhuis J, Nitta Y, Miller AD, Halbert CL, et al. (April 2000). "Adeno-associated virus vector transduction of vascular smooth muscle cells in vivo". Physiological Genomics. 2 (3): 117–27. doi:10.1152/physiolgenomics.2000.2.3.117. PMID 11015590. S2CID 14150468.
Koeberl DD, Alexander IE, Halbert CL, Russell DW, Miller AD (February 1997). "Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors". Proceedings of the National Academy of Sciences of the United States of America. 94 (4): 1426–31. Bibcode:1997PNAS...94.1426K. doi:10.1073/pnas.94.4.1426. PMC 19807. PMID 9037069.
Qing K, Mah C, Hansen J, Zhou S, Dwarki V, Srivastava A (January 1999). "Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2". Nature Medicine. 5 (1): 71–7. doi:10.1038/4758. PMID 9883842. S2CID 31602526.
Summerford C, Samulski RJ (February 1998). "Membrane-associated heparan sulfate proteo-glycan is a receptor for adeno-associated virus type 2 virions". Journal of Virology. 72 (2): 1438–45. doi:10.1128/JVI.72.2.1438-1445.1998. PMC 124624. PMID 9445046.
Summerford C, Bartlett JS, Samulski RJ (January 1999). "AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection". Nature Medicine. 5 (1): 78–82. doi:10.1038/4768. PMID 9883843. S2CID 23326070.
Qiu J, Handa A, Kirby M, Brown KE (March 2000). "The interaction of heparin sulfate and adeno-associated virus 2". Virology. 269 (1): 137–47. doi:10.1006/viro.2000.0205. PMID 10725206.
Pajusola K, Gruchala M, Joch H, Lüscher TF, Ylä-Herttuala S, Büeler H (November 2002). "Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells". Journal of Virology. 76 (22): 11530–40. doi:10.1128/JVI.76.22.11530-11540.2002. PMC 136795. PMID 12388714.
Limberis MP, Vandenberghe LH, Zhang L, Pickles RJ, Wilson JM (February 2009). "Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro". Molecular Therapy. 17 (2): 294–301. doi:10.1038/mt.2008.261. PMC 2835069. PMID 19066597.
Strobel B, Duechs MJ, Schmid R, Stierstorfer BE, Bucher H, Quast K, et al. (September 2015). "Modeling Pulmonary Disease Pathways Using Recombinant Adeno-Associated Virus 6.2". American Journal of Respiratory Cell and Molecular Biology. 53 (3): 291–302. doi:10.1165/rcmb.2014-0338MA. PMID 25845025.
Gao GP, Alvira MR, Wang L, Calcedo R, Johnston J, Wilson JM (September 2002). "Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy". Proceedings of the National Academy of Sciences of the United States of America. 99 (18): 11854–9. Bibcode:2002PNAS...9911854G. doi:10.1073/pnas.182412299. PMC 129358. PMID 12192090.
Halbert CL, Allen JM, Miller AD (July 2001). "Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors". Journal of Virology. 75 (14): 6615–24. doi:10.1128/JVI.75.14.6615-6624.2001. PMC 114385. PMID 11413329.
Rabinowitz JE, Bowles DE, Faust SM, Ledford JG, Cunningham SE, Samulski RJ (May 2004). "Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups". Journal of Virology. 78 (9): 4421–32. doi:10.1128/JVI.78.9.4421-4432.2004. PMC 387689. PMID 15078923.
Chen S, Kapturczak M, Loiler SA, Zolotukhin S, Glushakova OY, Madsen KM, et al. (February 2005). "Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors". Human Gene Therapy. 16 (2): 235–47. doi:10.1089/hum.2005.16.235. PMC 1364465. PMID 15761263.
Ortinski PI, Dong J, Mungenast A, Yue C, Takano H, Watson DJ, et al. (May 2010). "Selective induction of astrocytic gliosis generates deficits in neuronal inhibition". Nature Neuroscience. 13 (5): 584–91. doi:10.1038/nn.2535. PMC 3225960. PMID 20418874.
Kaludov N, Brown KE, Walters RW, Zabner J, Chiorini JA (August 2001). "Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity". Journal of Virology. 75 (15): 6884–93. doi:10.1128/JVI.75.15.6884-6893.2001. PMC 114416. PMID 11435568.
Di Pasquale G, Davidson BL, Stein CS, Martins I, Scudiero D, Monks A, et al. (October 2003). "Identification of PDGFR as a receptor for AAV-5 transduction". Nature Medicine. 9 (10): 1306–12. doi:10.1038/nm929. PMID 14502277. S2CID 32547188.
Excoffon, K, et al. (2009). "Directed evolution of adeno-associated virus to an infectious respiratory virus". Proceedings of the National Academy of Sciences. 106 (10): 3865–3870. Bibcode:2009PNAS..106.3865E. doi:10.1073/pnas.0813365106. PMC 2646629. PMID 19237554.
Zinn E, Pacouret S, Khaychuk V, Turunen HT, Carvalho LS, Andres-Mateos E, et al. (August 2015). "In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector". Cell Reports. 12 (6): 1056–68. doi:10.1016/j.celrep.2015.07.019. PMC 4536165. PMID 26235624.
Flotte TR, Berns KI (April 2005). "Adeno-associated virus: a ubiquitous commensal of mammals". Human Gene Therapy. 16 (4): 401–407. doi:10.1089/hum.2005.16.401. PMID 15871671.
Ronzitti G, Gross DA, Mingozzi F (2020). "Human Immune Responses to Adeno-Associated Virus (AAV) Vectors". Frontiers in Immunology. 11: 670. doi:10.3389/fimmu.2020.00670. PMC 7181373. PMID 32362898.
Vandamme C, Adjali O, Mingozzi F (November 2017). "Unraveling the Complex Story of Immune Responses to AAV Vectors Trial After Trial". Human Gene Therapy. 28 (11): 1061–1074. doi:10.1089/hum.2017.150. PMC 5649404. PMID 28835127.
Barnes C, Scheideler O, Schaffer D (December 2019). "Engineering the AAV capsid to evade immune responses". Current Opinion in Biotechnology. 60: 99–103. doi:10.1016/j.copbio.2019.01.002. PMC 7117822. PMID 30807882.
Zaiss AK, Liu Q, Bowen GP, Wong NC, Bartlett JS, Muruve DA (May 2002). "Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors". Journal of Virology. 76 (9): 4580–90. doi:10.1128/JVI.76.9.4580-4590.2002. PMC 155101. PMID 11932423.
Zhu J, Huang X, Yang Y (August 2009). "The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice". The Journal of Clinical Investigation. 119 (8): 2388–2398. doi:10.1172/JCI37607. PMC 2719948. PMID 19587448.
Martino AT, Suzuki M, Markusic DM, Zolotukhin I, Ryals RC, Moghimi B, et al. (June 2011). "The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver". Blood. 117 (24): 6459–6468. doi:10.1182/blood-2010-10-314518. PMC 3123017. PMID 21474674.
Calcedo R, Morizono H, Wang L, McCarter R, He J, Jones D, et al. (September 2011). "Adeno-associated virus antibody profiles in newborns, children, and adolescents". Clinical and Vaccine Immunology. 18 (9): 1586–1588. doi:10.1128/CVI.05107-11. PMC 3165215. PMID 21775517.
Tse LV, Klinc KA, Madigan VJ, Castellanos Rivera RM, Wells LF, Havlik LP, et al. (June 2017). "Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion". Proceedings of the National Academy of Sciences of the United States of America. 114 (24): E4812 – E4821. Bibcode:2017PNAS..114E4812T. doi:10.1073/pnas.1704766114. PMC 5474820. PMID 28559317.
Zaiss AK, Muruve DA (June 2005). "Immune responses to adeno-associated virus vectors". Current Gene Therapy. 5 (3): 323–31. doi:10.2174/1566523054065039. PMID 15975009.
Madsen D, Cantwell ER, O'Brien T, Johnson PA, Mahon BP (November 2009). "Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1". The Journal of General Virology. 90 (Pt 11): 2622–33. doi:10.1099/vir.0.014175-0. PMC 2885037. PMID 19641045.
Manno CS, Pierce GF, Arruda VR, Glader B, Ragni M, Rasko JJ, et al. (March 2006). "Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response". Nature Medicine. 12 (3): 342–7. doi:10.1038/nm1358. PMID 16474400. S2CID 14664182.
Sabatino DE, Mingozzi F, Hui DJ, Chen H, Colosi P, Ertl HC, et al. (December 2005). "Identification of mouse AAV capsid-specific CD8+ T cell epitopes". Molecular Therapy. 12 (6): 1023–33. doi:10.1016/j.ymthe.2005.09.009. PMID 16263332.
Rohr UP, Kronenwett R, Grimm D, Kleinschmidt J, Haas R (September 2002). "Primary human cells differ in their susceptibility to rAAV-2-mediated gene transfer and duration of reporter gene expression". Journal of Virological Methods. 105 (2): 265–75. doi:10.1016/S0166-0934(02)00117-9. PMID 12270659.
Matsushita T, Elliger S, Elliger C, Podsakoff G, Villarreal L, Kurtzman GJ, et al. (July 1998). "Adeno-associated virus vectors can be efficiently produced without helper virus". Gene Therapy. 5 (7): 938–45. doi:10.1038/sj.gt.3300680. PMID 9813665.
Myers MW, Laughlin CA, Jay FT, Carter BJ (July 1980). "Adenovirus helper function for growth of adeno-associated virus: effect of temperature-sensitive mutations in adenovirus early gene region 2". Journal of Virology. 35 (1): 65–75. doi:10.1128/JVI.35.1.65-75.1980. PMC 288783. PMID 6251278.
Handa H, Carter BJ (July 1979). "Adeno-associated virus DNA replication complexes in herpes simplex virus or adenovirus-infected cells". The Journal of Biological Chemistry. 254 (14): 6603–10. doi:10.1016/S0021-9258(18)50411-7. PMID 221504.
Yakobson B, Koch T, Winocour E (April 1987). "Replication of adeno-associated virus in synchronized cells without the addition of a helper virus". Journal of Virology. 61 (4): 972–81. doi:10.1128/JVI.61.4.972-981.1987. PMC 254052. PMID 3029431.
Yakobson B, Hrynko TA, Peak MJ, Winocour E (March 1989). "Replication of adeno-associated virus in cells irradiated with UV light at 254 nm". Journal of Virology. 63 (3): 1023–30. doi:10.1128/JVI.63.3.1023-1030.1989. PMC 247794. PMID 2536816.
Duan D, Sharma P, Yang J, Yue Y, Dudus L, Zhang Y, et al. (November 1998). "Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue". Journal of Virology. 72 (11): 8568–77. doi:10.1128/JVI.72.11.8568-8577.1998. PMC 110267. PMID 9765395.

fda.gov

"LUXTURNA". FDA - Approved Cell & Gene Therapy Products - LUXTURNA. 8 June 2022. Retrieved 3 December 2024.
"HEMGENIX". FDA - Approved Gene Therapy Products - HEMGENIX. 4 January 2023. Retrieved 3 December 2024.
"ROCTAVIAN". FDA - Approved Gene Therapy Products - ROCTAVIAN. 26 July 2023. Retrieved 3 December 2024.
"BEQVEZ". FDA - Approved Gene Therapy Products - BEQVEZ. 20 May 2024. Retrieved 3 December 2024.
"ELEVIDYS". FDA - Approved Gene Therapy Products - ELEVIDYS. 3 January 2025. Archived from the original on 23 June 2023. Retrieved 3 December 2024.
"ZOLGENSMA". FDA - Approved Gene Therapies - ZOLGENSMA. 6 February 2025. Retrieved 3 December 2024.
"KEBILIDI". FDA - Approved Gene Therapies - KEBILIDI. 13 December 2024. Retrieved 3 December 2024.

harvard.edu

ui.adsabs.harvard.edu

Tacke F (May 2023). "Severe hepatitis outbreak in children linked to AAV2 virus". Nature. 617 (7961): 471–472. Bibcode:2023Natur.617..471T. doi:10.1038/d41586-023-00570-8. PMID 36997704.
Servellita V, Sotomayor Gonzalez A, Lamson DM, Foresythe A, Huh HJ, Bazinet AL, et al. (May 2023). "Adeno-associated virus type 2 in US children with acute severe hepatitis". Nature. 617 (7961): 574–580. Bibcode:2023Natur.617..574S. doi:10.1038/s41586-023-05949-1. PMC 10170441. PMID 36996871.
Kotin RM, Siniscalco M, Samulski RJ, Zhu XD, Hunter L, Laughlin CA, et al. (March 1990). "Site-specific integration by adeno-associated virus". Proceedings of the National Academy of Sciences of the United States of America. 87 (6): 2211–5. Bibcode:1990PNAS...87.2211K. doi:10.1073/pnas.87.6.2211. PMC 53656. PMID 2156265.
Weitzman MD, Kyöstiö SR, Kotin RM, Owens RA (June 1994). "Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA". Proceedings of the National Academy of Sciences of the United States of America. 91 (13): 5808–12. Bibcode:1994PNAS...91.5808W. doi:10.1073/pnas.91.13.5808. PMC 44086. PMID 8016070.
Jay FT, Laughlin CA, Carter BJ (May 1981). "Eukaryotic translational control: adeno-associated virus protein synthesis is affected by a mutation in the adenovirus DNA-binding protein". Proceedings of the National Academy of Sciences of the United States of America. 78 (5): 2927–31. Bibcode:1981PNAS...78.2927J. doi:10.1073/pnas.78.5.2927. PMC 319472. PMID 6265925.
Sonntag F, Schmidt K, Kleinschmidt JA (June 2010). "A viral assembly factor promotes AAV2 capsid formation in the nucleolus". Proceedings of the National Academy of Sciences of the United States of America. 107 (22): 10220–5. Bibcode:2010PNAS..10710220S. doi:10.1073/pnas.1001673107. PMC 2890453. PMID 20479244.
Xie Q, Bu W, Bhatia S, Hare J, Somasundaram T, Azzi A, et al. (August 2002). "The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy". Proceedings of the National Academy of Sciences of the United States of America. 99 (16): 10405–10. Bibcode:2002PNAS...9910405X. doi:10.1073/pnas.162250899. PMC 124927. PMID 12136130.
Becerra SP, Rose JA, Hardy M, Baroudy BM, Anderson CW (December 1985). "Direct mapping of adeno-associated virus capsid proteins B and C: a possible ACG initiation codon". Proceedings of the National Academy of Sciences of the United States of America. 82 (23): 7919–23. Bibcode:1985PNAS...82.7919B. doi:10.1073/pnas.82.23.7919. PMC 390881. PMID 2999784.
Koeberl DD, Alexander IE, Halbert CL, Russell DW, Miller AD (February 1997). "Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors". Proceedings of the National Academy of Sciences of the United States of America. 94 (4): 1426–31. Bibcode:1997PNAS...94.1426K. doi:10.1073/pnas.94.4.1426. PMC 19807. PMID 9037069.
Gao GP, Alvira MR, Wang L, Calcedo R, Johnston J, Wilson JM (September 2002). "Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy". Proceedings of the National Academy of Sciences of the United States of America. 99 (18): 11854–9. Bibcode:2002PNAS...9911854G. doi:10.1073/pnas.182412299. PMC 129358. PMID 12192090.
Excoffon, K, et al. (2009). "Directed evolution of adeno-associated virus to an infectious respiratory virus". Proceedings of the National Academy of Sciences. 106 (10): 3865–3870. Bibcode:2009PNAS..106.3865E. doi:10.1073/pnas.0813365106. PMC 2646629. PMID 19237554.
Tse LV, Klinc KA, Madigan VJ, Castellanos Rivera RM, Wells LF, Havlik LP, et al. (June 2017). "Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion". Proceedings of the National Academy of Sciences of the United States of America. 114 (24): E4812 – E4821. Bibcode:2017PNAS..114E4812T. doi:10.1073/pnas.1704766114. PMC 5474820. PMID 28559317.

ictv.global

"Subfamily: Parvovirinae, Genus: Dependoparvovirus". International Committee on Taxonomy of Viruses (ICTV). Retrieved 31 January 2020.

nature.com

Ghosh, A., Yue, Y., Lai, Y., Duan, D. (2008). "A Hybrid Vector System Expands Adeno-associated Viral Vector Packaging Capacity in a Transgene- Independent manner" (PDF). Molecular Therapy. 16 (1): 124–130. doi:10.1038/sj.mt.6300322. PMID 17984978.{{cite journal}}: CS1 maint: overridden setting (link)

nih.gov

pubmed.ncbi.nlm.nih.gov

Naso MF, Tomkowicz B, Perry WL, Strohl WR (August 2017). "Adeno-Associated Virus (AAV) as a Vector for Gene Therapy". BioDrugs. 31 (4): 317–334. doi:10.1007/s40259-017-0234-5. PMC 5548848. PMID 28669112.
Wu Z, Yang H, Colosi P (January 2010). "Effect of genome size on AAV vector packaging". Molecular Therapy. 18 (1): 80–86. doi:10.1038/mt.2009.255. PMC 2839202. PMID 19904234.
Grieger JC, Samulski RJ (2005). "Adeno-associated Virus as a Gene Therapy Vector: Vector Development, Production and Clinical Applications". Adeno-associated virus as a gene therapy vector: vector development, production and clinical applications. Advances in Biochemical Engineering/Biotechnology. Vol. 99. pp. 119–45. doi:10.1007/10_005. ISBN 978-3-540-28404-8. PMID 16568890.
Deyle DR, Russell DW (August 2009). "Adeno-associated virus vector integration". Current Opinion in Molecular Therapeutics. 11 (4): 442–7. PMC 2929125. PMID 19649989.
Maguire AM, Simonelli F, Pierce EA, Pugh EN, Mingozzi F, Bennicelli J, et al. (May 2008). "Safety and efficacy of gene transfer for Leber's congenital amaurosis". The New England Journal of Medicine. 358 (21): 2240–8. doi:10.1056/NEJMoa0802315. PMC 2829748. PMID 18441370.
Tacke F (May 2023). "Severe hepatitis outbreak in children linked to AAV2 virus". Nature. 617 (7961): 471–472. Bibcode:2023Natur.617..471T. doi:10.1038/d41586-023-00570-8. PMID 36997704.
Servellita V, Sotomayor Gonzalez A, Lamson DM, Foresythe A, Huh HJ, Bazinet AL, et al. (May 2023). "Adeno-associated virus type 2 in US children with acute severe hepatitis". Nature. 617 (7961): 574–580. Bibcode:2023Natur.617..574S. doi:10.1038/s41586-023-05949-1. PMC 10170441. PMID 36996871.
Carter BJ (December 2004). "Adeno-associated virus and the development of adeno-associated virus vectors: a historical perspective". Molecular Therapy. 10 (6): 981–9. doi:10.1016/j.ymthe.2004.09.011. PMID 15564130.
Kotin RM, Siniscalco M, Samulski RJ, Zhu XD, Hunter L, Laughlin CA, et al. (March 1990). "Site-specific integration by adeno-associated virus". Proceedings of the National Academy of Sciences of the United States of America. 87 (6): 2211–5. Bibcode:1990PNAS...87.2211K. doi:10.1073/pnas.87.6.2211. PMC 53656. PMID 2156265.
Surosky RT, Urabe M, Godwin SG, McQuiston SA, Kurtzman GJ, Ozawa K, et al. (October 1997). "Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome". Journal of Virology. 71 (10): 7951–9. doi:10.1128/JVI.71.10.7951-7959.1997. PMC 192153. PMID 9311886.
Daya S, Berns KI (October 2008). "Gene therapy using adeno-associated virus vectors". Clinical Microbiology Reviews. 21 (4): 583–93. doi:10.1128/CMR.00008-08. PMC 2570152. PMID 18854481.
Chirmule N, Propert K, Magosin S, Qian Y, Qian R, Wilson J (September 1999). "Immune responses to adenovirus and adeno-associated virus in humans". Gene Therapy. 6 (9): 1574–83. doi:10.1038/sj.gt.3300994. PMID 10490767.
Hernandez YJ, Wang J, Kearns WG, Loiler S, Poirier A, Flotte TR (October 1999). "Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model". Journal of Virology. 73 (10): 8549–58. doi:10.1128/JVI.73.10.8549-8558.1999. PMC 112875. PMID 10482608.
Ponnazhagan S, Mukherjee P, Yoder MC, Wang XS, Zhou SZ, Kaplan J, et al. (April 1997). "Adeno-associated virus 2-mediated gene transfer in vivo: organ-tropism and expression of transduced sequences in mice". Gene. 190 (1): 203–10. doi:10.1016/S0378-1119(96)00576-8. PMID 9185868.
Ghosh, A., Yue, Y., Lai, Y., Duan, D. (2008). "A Hybrid Vector System Expands Adeno-associated Viral Vector Packaging Capacity in a Transgene- Independent manner" (PDF). Molecular Therapy. 16 (1): 124–130. doi:10.1038/sj.mt.6300322. PMID 17984978.{{cite journal}}: CS1 maint: overridden setting (link)
Bak RO, Porteus MH (July 2017). "CRISPR-Mediated Integration of Large Gene Cassettes Using AAV Donor Vectors". Cell Reports. 20 (3): 750–756. doi:10.1016/j.celrep.2017.06.064. PMC 5568673. PMID 28723575.
McCarty DM, Monahan PE, Samulski RJ (August 2001). "Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis". Gene Therapy. 8 (16): 1248–54. doi:10.1038/sj.gt.3301514. PMID 11509958.
Rogers GL, Martino AT, Zolotukhin I, Ertl HC, Herzog RW (January 2014). "Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B". Journal of Translational Medicine. 12: 25. doi:10.1186/1479-5876-12-25. PMC 3904690. PMID 24460861.
Bainbridge JW, Smith AJ, Barker SS, Robbie S, Henderson R, Balaggan K, et al. (May 2008). "Effect of gene therapy on visual function in Leber's congenital amaurosis". The New England Journal of Medicine. 358 (21): 2231–9. CiteSeerX 10.1.1.574.4003. doi:10.1056/NEJMoa0802268. PMID 18441371.
Hauswirth WW, Aleman TS, Kaushal S, Cideciyan AV, Schwartz SB, Wang L, et al. (October 2008). "Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial". Human Gene Therapy. 19 (10): 979–90. doi:10.1089/hum.2008.107. PMC 2940541. PMID 18774912.
Nathwani AC, Tuddenham EG, Rangarajan S, Rosales C, McIntosh J, Linch DC, et al. (December 2011). "Adenovirus-associated virus vector-mediated gene transfer in hemophilia B". The New England Journal of Medicine. 365 (25): 2357–65. doi:10.1056/NEJMoa1108046. PMC 3265081. PMID 22149959.
Jessup M, Greenberg B, Mancini D, Cappola T, Pauly DF, Jaski B, et al. (July 2011). "Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure". Circulation. 124 (3): 304–13. doi:10.1161/CIRCULATIONAHA.111.022889. PMC 5843948. PMID 21709064.
Gaudet D, Méthot J, Déry S, Brisson D, Essiembre C, Tremblay G, et al. (April 2013). "Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial". Gene Ther. 20 (4): 361–9. doi:10.1038/gt.2012.43. PMC 4956470. PMID 22717743.
LeWitt PA, Rezai AR, Leehey MA, Ojemann SG, Flaherty AW, Eskandar EN, et al. (April 2011). "AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial". The Lancet. Neurology. 10 (4): 309–19. doi:10.1016/S1474-4422(11)70039-4. PMID 21419704. S2CID 37154043.
Carter BJ (May 2005). "Adeno-associated virus vectors in clinical trials". Human Gene Therapy. 16 (5): 541–50. doi:10.1089/hum.2005.16.541. PMID 15916479.
Kaplitt MG, Feigin A, Tang C, Fitzsimons HL, Mattis P, Lawlor PA, et al. (June 2007). "Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial". Lancet. 369 (9579): 2097–105. doi:10.1016/S0140-6736(07)60982-9. PMID 17586305. S2CID 24491886.
Bohenzky RA, LeFebvre RB, Berns KI (October 1988). "Sequence and symmetry requirements within the internal palindromic sequences of the adeno-associated virus terminal repeat". Virology. 166 (2): 316–27. doi:10.1016/0042-6822(88)90502-8. PMID 2845646.
Wang XS, Ponnazhagan S, Srivastava A (July 1995). "Rescue and replication signals of the adeno-associated virus 2 genome". Journal of Molecular Biology. 250 (5): 573–80. doi:10.1006/jmbi.1995.0398. PMID 7623375.
Weitzman MD, Kyöstiö SR, Kotin RM, Owens RA (June 1994). "Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA". Proceedings of the National Academy of Sciences of the United States of America. 91 (13): 5808–12. Bibcode:1994PNAS...91.5808W. doi:10.1073/pnas.91.13.5808. PMC 44086. PMID 8016070.
Zhou X, Muzyczka N (April 1998). "In vitro packaging of adeno-associated virus DNA". Journal of Virology. 72 (4): 3241–7. doi:10.1128/JVI.72.4.3241-3247.1998. PMC 109794. PMID 9525651.
Nony P, Tessier J, Chadeuf G, Ward P, Giraud A, Dugast M, et al. (October 2001). "Novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences". Journal of Virology. 75 (20): 9991–4. doi:10.1128/JVI.75.20.9991-9994.2001. PMC 114572. PMID 11559833.
Nony P, Chadeuf G, Tessier J, Moullier P, Salvetti A (January 2003). "Evidence for packaging of rep-cap sequences into adeno-associated virus (AAV) type 2 capsids in the absence of inverted terminal repeats: a model for generation of rep-positive AAV particles". Journal of Virology. 77 (1): 776–81. doi:10.1128/JVI.77.1.776-781.2003. PMC 140600. PMID 12477885.
Philpott NJ, Giraud-Wali C, Dupuis C, Gomos J, Hamilton H, Berns KI, et al. (June 2002). "Efficient integration of recombinant adeno-associated virus DNA vectors requires a p5-rep sequence in cis". Journal of Virology. 76 (11): 5411–21. doi:10.1128/JVI.76.11.5411-5421.2002. PMC 137060. PMID 11991970.
Tullis GE, Shenk T (December 2000). "Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal size". Journal of Virology. 74 (24): 11511–21. doi:10.1128/JVI.74.24.11511-11521.2000. PMC 112431. PMID 11090148.
Kyöstiö SR, Owens RA, Weitzman MD, Antoni BA, Chejanovsky N, Carter BJ (May 1994). "Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levels". Journal of Virology. 68 (5): 2947–57. doi:10.1128/JVI.68.5.2947-2957.1994. PMC 236783. PMID 8151765.
Im DS, Muzyczka N (May 1990). "The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity". Cell. 61 (3): 447–57. doi:10.1016/0092-8674(90)90526-K. PMID 2159383. S2CID 27997617.
Im DS, Muzyczka N (February 1992). "Partial purification of adeno-associated virus Rep78, Rep52, and Rep40 and their biochemical characterization". Journal of Virology. 66 (2): 1119–28. doi:10.1128/JVI.66.2.1119-1128.1992. PMC 240816. PMID 1309894.
Samulski RJ (2003). "AAV Vectors, the Future Workhorse of Human Gene Therapy". Ernst Schering Research Foundation Workshop. Human Gene Therapy: Current Opportunities and Future Trends. pp. 25–40. doi:10.1007/978-3-662-05352-2_3. ISBN 978-3-662-05354-6. PMID 12894449.
Trempe JP, Carter BJ (January 1988). "Regulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translation". Journal of Virology. 62 (1): 68–74. doi:10.1128/JVI.62.1.68-74.1988. PMC 250502. PMID 2824856.
Jay FT, Laughlin CA, Carter BJ (May 1981). "Eukaryotic translational control: adeno-associated virus protein synthesis is affected by a mutation in the adenovirus DNA-binding protein". Proceedings of the National Academy of Sciences of the United States of America. 78 (5): 2927–31. Bibcode:1981PNAS...78.2927J. doi:10.1073/pnas.78.5.2927. PMC 319472. PMID 6265925.
Sonntag F, Schmidt K, Kleinschmidt JA (June 2010). "A viral assembly factor promotes AAV2 capsid formation in the nucleolus". Proceedings of the National Academy of Sciences of the United States of America. 107 (22): 10220–5. Bibcode:2010PNAS..10710220S. doi:10.1073/pnas.1001673107. PMC 2890453. PMID 20479244.
Pierson EE, Keifer DZ, Asokan A, Jarrold MF (July 2016). "Resolving Adeno-Associated Viral Particle Diversity With Charge Detection Mass Spectrometry". Analytical Chemistry. 88 (13). American Chemical Society (ACS): 6718–6725. doi:10.1021/acs.analchem.6b00883. PMC 6537880. PMID 27310298.
Xie Q, Bu W, Bhatia S, Hare J, Somasundaram T, Azzi A, et al. (August 2002). "The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy". Proceedings of the National Academy of Sciences of the United States of America. 99 (16): 10405–10. Bibcode:2002PNAS...9910405X. doi:10.1073/pnas.162250899. PMC 124927. PMID 12136130.
Sonntag F, Köther K, Schmidt K, Weghofer M, Raupp C, Nieto K, et al. (December 2011). "The assembly-activating protein promotes capsid assembly of different adeno-associated virus serotypes". Journal of Virology. 85 (23): 12686–97. doi:10.1128/JVI.05359-11. PMC 3209379. PMID 21917944.
Becerra SP, Rose JA, Hardy M, Baroudy BM, Anderson CW (December 1985). "Direct mapping of adeno-associated virus capsid proteins B and C: a possible ACG initiation codon". Proceedings of the National Academy of Sciences of the United States of America. 82 (23): 7919–23. Bibcode:1985PNAS...82.7919B. doi:10.1073/pnas.82.23.7919. PMC 390881. PMID 2999784.
Cassinotti P, Weitz M, Tratschin JD (November 1988). "Organization of the adeno-associated virus (AAV) capsid gene: mapping of a minor spliced mRNA coding for virus capsid protein 1". Virology. 167 (1): 176–84. doi:10.1016/0042-6822(88)90067-0. PMID 2847413.
Muralidhar S, Becerra SP, Rose JA (January 1994). "Site-directed mutagenesis of adeno-associated virus type 2 structural protein initiation codons: effects on regulation of synthesis and biological activity". Journal of Virology. 68 (1): 170–6. doi:10.1128/JVI.68.1.170-176.1994. PMC 236275. PMID 8254726.
Trempe JP, Carter BJ (September 1988). "Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein". Journal of Virology. 62 (9): 3356–63. doi:10.1128/JVI.62.9.3356-3363.1988. PMC 253458. PMID 2841488.
Rabinowitz JE, Samulski RJ (December 2000). "Building a better vector: the manipulation of AAV virions". Virology. 278 (2): 301–8. doi:10.1006/viro.2000.0707. PMID 11118354.
Girod A, Wobus CE, Zádori Z, Ried M, Leike K, Tijssen P, et al. (May 2002). "The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity". The Journal of General Virology. 83 (Pt 5): 973–8. doi:10.1099/0022-1317-83-5-973. PMID 11961250.
Warrington KH, Gorbatyuk OS, Harrison JK, Opie SR, Zolotukhin S, Muzyczka N (June 2004). "Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus". Journal of Virology. 78 (12): 6595–609. doi:10.1128/JVI.78.12.6595-6609.2004. PMC 416546. PMID 15163751.
Rumachik NG, Malaker SA, Poweleit N, Maynard LH, Adams CM, Leib RD, et al. (May 2020). "Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors". Molecular Therapy – Methods & Clinical Development. 18: 98–118. doi:10.1016/j.omtm.2020.05.018. PMC 7488757. PMID 32995354.
Chen Q, Njenga R, Leuchs B, Chiocca S, Kleinschmidt J, Muller M (September 2020). "SUMOylation Targets Adeno-associated Virus Capsids but Mainly Restricts Transduction by Cellular Mechanisms". Journal of Virology. 94 (19): e00871-20. doi:10.1128/JVI.00871-20. PMC 7495375. PMID 32669341.
Giles AR, Sims JJ, Turner KB, Govindasamy L, Alvira MR, Lock M, et al. (December 2018). "Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function". Molecular Therapy. 26 (12): 2848–2862. doi:10.1016/j.ymthe.2018.09.013. PMC 6277538. PMID 30343890.
Mori S, Wang L, Takeuchi T, Kanda T (December 2004). "Two novel adeno-associated viruses from cynomolgus monkey: pseudotyping characterization of capsid protein". Virology. 330 (2): 375–83. doi:10.1016/j.virol.2004.10.012. PMID 15567432.
Issa SS, Shaimardanova AA, Solovyeva VV, Rizvanov AA (1 March 2023). "Various AAV Serotypes and Their Applications in Gene Therapy: An Overview". Cells. 12 (5): 785. doi:10.3390/cells12050785. PMC 10000783. PMID 36899921.
Bartlett JS, Samulski RJ, McCown TJ (May 1998). "Selective and rapid uptake of adeno-associated virus type 2 in brain". Human Gene Therapy. 9 (8): 1181–6. doi:10.1089/hum.1998.9.8-1181. PMID 9625257.
Fischer AC, Beck SE, Smith CI, Laube BL, Askin FB, Guggino SE, et al. (December 2003). "Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques". Molecular Therapy. 8 (6): 918–26. doi:10.1016/j.ymthe.2003.08.015. PMID 14664794.
Nicklin SA, Buening H, Dishart KL, de Alwis M, Girod A, Hacker U, et al. (September 2001). "Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells". Molecular Therapy. 4 (3): 174–81. doi:10.1006/mthe.2001.0424. PMID 11545607.
Rabinowitz JE, Xiao W, Samulski RJ (December 1999). "Insertional mutagenesis of AAV2 capsid and the production of recombinant virus". Virology. 265 (2): 274–85. doi:10.1006/viro.1999.0045. PMID 10600599.
Shi W, Bartlett JS (April 2003). "RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism". Molecular Therapy. 7 (4): 515–25. doi:10.1016/S1525-0016(03)00042-X. PMID 12727115.
Wu P, Xiao W, Conlon T, Hughes J, Agbandje-McKenna M, Ferkol T, et al. (September 2000). "Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism". Journal of Virology. 74 (18): 8635–47. doi:10.1128/JVI.74.18.8635-8647.2000. PMC 102071. PMID 10954565.
Manno CS, Chew AJ, Hutchison S, Larson PJ, Herzog RW, Arruda VR, et al. (April 2003). "AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B". Blood. 101 (8): 2963–72. doi:10.1182/blood-2002-10-3296. PMID 12515715.
Richter M, Iwata A, Nyhuis J, Nitta Y, Miller AD, Halbert CL, et al. (April 2000). "Adeno-associated virus vector transduction of vascular smooth muscle cells in vivo". Physiological Genomics. 2 (3): 117–27. doi:10.1152/physiolgenomics.2000.2.3.117. PMID 11015590. S2CID 14150468.
Koeberl DD, Alexander IE, Halbert CL, Russell DW, Miller AD (February 1997). "Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors". Proceedings of the National Academy of Sciences of the United States of America. 94 (4): 1426–31. Bibcode:1997PNAS...94.1426K. doi:10.1073/pnas.94.4.1426. PMC 19807. PMID 9037069.
Qing K, Mah C, Hansen J, Zhou S, Dwarki V, Srivastava A (January 1999). "Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2". Nature Medicine. 5 (1): 71–7. doi:10.1038/4758. PMID 9883842. S2CID 31602526.
Summerford C, Samulski RJ (February 1998). "Membrane-associated heparan sulfate proteo-glycan is a receptor for adeno-associated virus type 2 virions". Journal of Virology. 72 (2): 1438–45. doi:10.1128/JVI.72.2.1438-1445.1998. PMC 124624. PMID 9445046.
Summerford C, Bartlett JS, Samulski RJ (January 1999). "AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection". Nature Medicine. 5 (1): 78–82. doi:10.1038/4768. PMID 9883843. S2CID 23326070.
Qiu J, Handa A, Kirby M, Brown KE (March 2000). "The interaction of heparin sulfate and adeno-associated virus 2". Virology. 269 (1): 137–47. doi:10.1006/viro.2000.0205. PMID 10725206.
Pajusola K, Gruchala M, Joch H, Lüscher TF, Ylä-Herttuala S, Büeler H (November 2002). "Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells". Journal of Virology. 76 (22): 11530–40. doi:10.1128/JVI.76.22.11530-11540.2002. PMC 136795. PMID 12388714.
Limberis MP, Vandenberghe LH, Zhang L, Pickles RJ, Wilson JM (February 2009). "Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro". Molecular Therapy. 17 (2): 294–301. doi:10.1038/mt.2008.261. PMC 2835069. PMID 19066597.
Strobel B, Duechs MJ, Schmid R, Stierstorfer BE, Bucher H, Quast K, et al. (September 2015). "Modeling Pulmonary Disease Pathways Using Recombinant Adeno-Associated Virus 6.2". American Journal of Respiratory Cell and Molecular Biology. 53 (3): 291–302. doi:10.1165/rcmb.2014-0338MA. PMID 25845025.
Gao GP, Alvira MR, Wang L, Calcedo R, Johnston J, Wilson JM (September 2002). "Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy". Proceedings of the National Academy of Sciences of the United States of America. 99 (18): 11854–9. Bibcode:2002PNAS...9911854G. doi:10.1073/pnas.182412299. PMC 129358. PMID 12192090.
Halbert CL, Allen JM, Miller AD (July 2001). "Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors". Journal of Virology. 75 (14): 6615–24. doi:10.1128/JVI.75.14.6615-6624.2001. PMC 114385. PMID 11413329.
Rabinowitz JE, Bowles DE, Faust SM, Ledford JG, Cunningham SE, Samulski RJ (May 2004). "Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups". Journal of Virology. 78 (9): 4421–32. doi:10.1128/JVI.78.9.4421-4432.2004. PMC 387689. PMID 15078923.
Chen S, Kapturczak M, Loiler SA, Zolotukhin S, Glushakova OY, Madsen KM, et al. (February 2005). "Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors". Human Gene Therapy. 16 (2): 235–47. doi:10.1089/hum.2005.16.235. PMC 1364465. PMID 15761263.
Ortinski PI, Dong J, Mungenast A, Yue C, Takano H, Watson DJ, et al. (May 2010). "Selective induction of astrocytic gliosis generates deficits in neuronal inhibition". Nature Neuroscience. 13 (5): 584–91. doi:10.1038/nn.2535. PMC 3225960. PMID 20418874.
Kaludov N, Brown KE, Walters RW, Zabner J, Chiorini JA (August 2001). "Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity". Journal of Virology. 75 (15): 6884–93. doi:10.1128/JVI.75.15.6884-6893.2001. PMC 114416. PMID 11435568.
Di Pasquale G, Davidson BL, Stein CS, Martins I, Scudiero D, Monks A, et al. (October 2003). "Identification of PDGFR as a receptor for AAV-5 transduction". Nature Medicine. 9 (10): 1306–12. doi:10.1038/nm929. PMID 14502277. S2CID 32547188.
Excoffon, K, et al. (2009). "Directed evolution of adeno-associated virus to an infectious respiratory virus". Proceedings of the National Academy of Sciences. 106 (10): 3865–3870. Bibcode:2009PNAS..106.3865E. doi:10.1073/pnas.0813365106. PMC 2646629. PMID 19237554.
Zinn E, Pacouret S, Khaychuk V, Turunen HT, Carvalho LS, Andres-Mateos E, et al. (August 2015). "In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector". Cell Reports. 12 (6): 1056–68. doi:10.1016/j.celrep.2015.07.019. PMC 4536165. PMID 26235624.
Flotte TR, Berns KI (April 2005). "Adeno-associated virus: a ubiquitous commensal of mammals". Human Gene Therapy. 16 (4): 401–407. doi:10.1089/hum.2005.16.401. PMID 15871671.
Ronzitti G, Gross DA, Mingozzi F (2020). "Human Immune Responses to Adeno-Associated Virus (AAV) Vectors". Frontiers in Immunology. 11: 670. doi:10.3389/fimmu.2020.00670. PMC 7181373. PMID 32362898.
Vandamme C, Adjali O, Mingozzi F (November 2017). "Unraveling the Complex Story of Immune Responses to AAV Vectors Trial After Trial". Human Gene Therapy. 28 (11): 1061–1074. doi:10.1089/hum.2017.150. PMC 5649404. PMID 28835127.
Barnes C, Scheideler O, Schaffer D (December 2019). "Engineering the AAV capsid to evade immune responses". Current Opinion in Biotechnology. 60: 99–103. doi:10.1016/j.copbio.2019.01.002. PMC 7117822. PMID 30807882.
Zaiss AK, Liu Q, Bowen GP, Wong NC, Bartlett JS, Muruve DA (May 2002). "Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors". Journal of Virology. 76 (9): 4580–90. doi:10.1128/JVI.76.9.4580-4590.2002. PMC 155101. PMID 11932423.
Zhu J, Huang X, Yang Y (August 2009). "The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice". The Journal of Clinical Investigation. 119 (8): 2388–2398. doi:10.1172/JCI37607. PMC 2719948. PMID 19587448.
Martino AT, Suzuki M, Markusic DM, Zolotukhin I, Ryals RC, Moghimi B, et al. (June 2011). "The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver". Blood. 117 (24): 6459–6468. doi:10.1182/blood-2010-10-314518. PMC 3123017. PMID 21474674.
Calcedo R, Morizono H, Wang L, McCarter R, He J, Jones D, et al. (September 2011). "Adeno-associated virus antibody profiles in newborns, children, and adolescents". Clinical and Vaccine Immunology. 18 (9): 1586–1588. doi:10.1128/CVI.05107-11. PMC 3165215. PMID 21775517.
Tse LV, Klinc KA, Madigan VJ, Castellanos Rivera RM, Wells LF, Havlik LP, et al. (June 2017). "Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion". Proceedings of the National Academy of Sciences of the United States of America. 114 (24): E4812 – E4821. Bibcode:2017PNAS..114E4812T. doi:10.1073/pnas.1704766114. PMC 5474820. PMID 28559317.
Zaiss AK, Muruve DA (June 2005). "Immune responses to adeno-associated virus vectors". Current Gene Therapy. 5 (3): 323–31. doi:10.2174/1566523054065039. PMID 15975009.
Madsen D, Cantwell ER, O'Brien T, Johnson PA, Mahon BP (November 2009). "Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1". The Journal of General Virology. 90 (Pt 11): 2622–33. doi:10.1099/vir.0.014175-0. PMC 2885037. PMID 19641045.
Manno CS, Pierce GF, Arruda VR, Glader B, Ragni M, Rasko JJ, et al. (March 2006). "Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response". Nature Medicine. 12 (3): 342–7. doi:10.1038/nm1358. PMID 16474400. S2CID 14664182.
Sabatino DE, Mingozzi F, Hui DJ, Chen H, Colosi P, Ertl HC, et al. (December 2005). "Identification of mouse AAV capsid-specific CD8+ T cell epitopes". Molecular Therapy. 12 (6): 1023–33. doi:10.1016/j.ymthe.2005.09.009. PMID 16263332.
Rohr UP, Kronenwett R, Grimm D, Kleinschmidt J, Haas R (September 2002). "Primary human cells differ in their susceptibility to rAAV-2-mediated gene transfer and duration of reporter gene expression". Journal of Virological Methods. 105 (2): 265–75. doi:10.1016/S0166-0934(02)00117-9. PMID 12270659.
Matsushita T, Elliger S, Elliger C, Podsakoff G, Villarreal L, Kurtzman GJ, et al. (July 1998). "Adeno-associated virus vectors can be efficiently produced without helper virus". Gene Therapy. 5 (7): 938–45. doi:10.1038/sj.gt.3300680. PMID 9813665.
Myers MW, Laughlin CA, Jay FT, Carter BJ (July 1980). "Adenovirus helper function for growth of adeno-associated virus: effect of temperature-sensitive mutations in adenovirus early gene region 2". Journal of Virology. 35 (1): 65–75. doi:10.1128/JVI.35.1.65-75.1980. PMC 288783. PMID 6251278.
Handa H, Carter BJ (July 1979). "Adeno-associated virus DNA replication complexes in herpes simplex virus or adenovirus-infected cells". The Journal of Biological Chemistry. 254 (14): 6603–10. doi:10.1016/S0021-9258(18)50411-7. PMID 221504.
Yalkinoglu AO, Heilbronn R, Bürkle A, Schlehofer JR, zur Hausen H (June 1988). "DNA amplification of adeno-associated virus as a response to cellular genotoxic stress". Cancer Research. 48 (11): 3123–9. PMID 2835153.
Yakobson B, Koch T, Winocour E (April 1987). "Replication of adeno-associated virus in synchronized cells without the addition of a helper virus". Journal of Virology. 61 (4): 972–81. doi:10.1128/JVI.61.4.972-981.1987. PMC 254052. PMID 3029431.
Yakobson B, Hrynko TA, Peak MJ, Winocour E (March 1989). "Replication of adeno-associated virus in cells irradiated with UV light at 254 nm". Journal of Virology. 63 (3): 1023–30. doi:10.1128/JVI.63.3.1023-1030.1989. PMC 247794. PMID 2536816.
Duan D, Sharma P, Yang J, Yue Y, Dudus L, Zhang Y, et al. (November 1998). "Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue". Journal of Virology. 72 (11): 8568–77. doi:10.1128/JVI.72.11.8568-8577.1998. PMC 110267. PMID 9765395.

ncbi.nlm.nih.gov

Naso MF, Tomkowicz B, Perry WL, Strohl WR (August 2017). "Adeno-Associated Virus (AAV) as a Vector for Gene Therapy". BioDrugs. 31 (4): 317–334. doi:10.1007/s40259-017-0234-5. PMC 5548848. PMID 28669112.
Wu Z, Yang H, Colosi P (January 2010). "Effect of genome size on AAV vector packaging". Molecular Therapy. 18 (1): 80–86. doi:10.1038/mt.2009.255. PMC 2839202. PMID 19904234.
Deyle DR, Russell DW (August 2009). "Adeno-associated virus vector integration". Current Opinion in Molecular Therapeutics. 11 (4): 442–7. PMC 2929125. PMID 19649989.
Maguire AM, Simonelli F, Pierce EA, Pugh EN, Mingozzi F, Bennicelli J, et al. (May 2008). "Safety and efficacy of gene transfer for Leber's congenital amaurosis". The New England Journal of Medicine. 358 (21): 2240–8. doi:10.1056/NEJMoa0802315. PMC 2829748. PMID 18441370.
Servellita V, Sotomayor Gonzalez A, Lamson DM, Foresythe A, Huh HJ, Bazinet AL, et al. (May 2023). "Adeno-associated virus type 2 in US children with acute severe hepatitis". Nature. 617 (7961): 574–580. Bibcode:2023Natur.617..574S. doi:10.1038/s41586-023-05949-1. PMC 10170441. PMID 36996871.
Kotin RM, Siniscalco M, Samulski RJ, Zhu XD, Hunter L, Laughlin CA, et al. (March 1990). "Site-specific integration by adeno-associated virus". Proceedings of the National Academy of Sciences of the United States of America. 87 (6): 2211–5. Bibcode:1990PNAS...87.2211K. doi:10.1073/pnas.87.6.2211. PMC 53656. PMID 2156265.
Surosky RT, Urabe M, Godwin SG, McQuiston SA, Kurtzman GJ, Ozawa K, et al. (October 1997). "Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome". Journal of Virology. 71 (10): 7951–9. doi:10.1128/JVI.71.10.7951-7959.1997. PMC 192153. PMID 9311886.
Daya S, Berns KI (October 2008). "Gene therapy using adeno-associated virus vectors". Clinical Microbiology Reviews. 21 (4): 583–93. doi:10.1128/CMR.00008-08. PMC 2570152. PMID 18854481.
Hernandez YJ, Wang J, Kearns WG, Loiler S, Poirier A, Flotte TR (October 1999). "Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model". Journal of Virology. 73 (10): 8549–58. doi:10.1128/JVI.73.10.8549-8558.1999. PMC 112875. PMID 10482608.
Bak RO, Porteus MH (July 2017). "CRISPR-Mediated Integration of Large Gene Cassettes Using AAV Donor Vectors". Cell Reports. 20 (3): 750–756. doi:10.1016/j.celrep.2017.06.064. PMC 5568673. PMID 28723575.
Rogers GL, Martino AT, Zolotukhin I, Ertl HC, Herzog RW (January 2014). "Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B". Journal of Translational Medicine. 12: 25. doi:10.1186/1479-5876-12-25. PMC 3904690. PMID 24460861.
Hauswirth WW, Aleman TS, Kaushal S, Cideciyan AV, Schwartz SB, Wang L, et al. (October 2008). "Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial". Human Gene Therapy. 19 (10): 979–90. doi:10.1089/hum.2008.107. PMC 2940541. PMID 18774912.
Nathwani AC, Tuddenham EG, Rangarajan S, Rosales C, McIntosh J, Linch DC, et al. (December 2011). "Adenovirus-associated virus vector-mediated gene transfer in hemophilia B". The New England Journal of Medicine. 365 (25): 2357–65. doi:10.1056/NEJMoa1108046. PMC 3265081. PMID 22149959.
Jessup M, Greenberg B, Mancini D, Cappola T, Pauly DF, Jaski B, et al. (July 2011). "Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure". Circulation. 124 (3): 304–13. doi:10.1161/CIRCULATIONAHA.111.022889. PMC 5843948. PMID 21709064.
Gaudet D, Méthot J, Déry S, Brisson D, Essiembre C, Tremblay G, et al. (April 2013). "Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial". Gene Ther. 20 (4): 361–9. doi:10.1038/gt.2012.43. PMC 4956470. PMID 22717743.
Weitzman MD, Kyöstiö SR, Kotin RM, Owens RA (June 1994). "Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA". Proceedings of the National Academy of Sciences of the United States of America. 91 (13): 5808–12. Bibcode:1994PNAS...91.5808W. doi:10.1073/pnas.91.13.5808. PMC 44086. PMID 8016070.
Zhou X, Muzyczka N (April 1998). "In vitro packaging of adeno-associated virus DNA". Journal of Virology. 72 (4): 3241–7. doi:10.1128/JVI.72.4.3241-3247.1998. PMC 109794. PMID 9525651.
Nony P, Tessier J, Chadeuf G, Ward P, Giraud A, Dugast M, et al. (October 2001). "Novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences". Journal of Virology. 75 (20): 9991–4. doi:10.1128/JVI.75.20.9991-9994.2001. PMC 114572. PMID 11559833.
Nony P, Chadeuf G, Tessier J, Moullier P, Salvetti A (January 2003). "Evidence for packaging of rep-cap sequences into adeno-associated virus (AAV) type 2 capsids in the absence of inverted terminal repeats: a model for generation of rep-positive AAV particles". Journal of Virology. 77 (1): 776–81. doi:10.1128/JVI.77.1.776-781.2003. PMC 140600. PMID 12477885.
Philpott NJ, Giraud-Wali C, Dupuis C, Gomos J, Hamilton H, Berns KI, et al. (June 2002). "Efficient integration of recombinant adeno-associated virus DNA vectors requires a p5-rep sequence in cis". Journal of Virology. 76 (11): 5411–21. doi:10.1128/JVI.76.11.5411-5421.2002. PMC 137060. PMID 11991970.
Tullis GE, Shenk T (December 2000). "Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal size". Journal of Virology. 74 (24): 11511–21. doi:10.1128/JVI.74.24.11511-11521.2000. PMC 112431. PMID 11090148.
Kyöstiö SR, Owens RA, Weitzman MD, Antoni BA, Chejanovsky N, Carter BJ (May 1994). "Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levels". Journal of Virology. 68 (5): 2947–57. doi:10.1128/JVI.68.5.2947-2957.1994. PMC 236783. PMID 8151765.
Im DS, Muzyczka N (February 1992). "Partial purification of adeno-associated virus Rep78, Rep52, and Rep40 and their biochemical characterization". Journal of Virology. 66 (2): 1119–28. doi:10.1128/JVI.66.2.1119-1128.1992. PMC 240816. PMID 1309894.
Trempe JP, Carter BJ (January 1988). "Regulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translation". Journal of Virology. 62 (1): 68–74. doi:10.1128/JVI.62.1.68-74.1988. PMC 250502. PMID 2824856.
Jay FT, Laughlin CA, Carter BJ (May 1981). "Eukaryotic translational control: adeno-associated virus protein synthesis is affected by a mutation in the adenovirus DNA-binding protein". Proceedings of the National Academy of Sciences of the United States of America. 78 (5): 2927–31. Bibcode:1981PNAS...78.2927J. doi:10.1073/pnas.78.5.2927. PMC 319472. PMID 6265925.
Sonntag F, Schmidt K, Kleinschmidt JA (June 2010). "A viral assembly factor promotes AAV2 capsid formation in the nucleolus". Proceedings of the National Academy of Sciences of the United States of America. 107 (22): 10220–5. Bibcode:2010PNAS..10710220S. doi:10.1073/pnas.1001673107. PMC 2890453. PMID 20479244.
Pierson EE, Keifer DZ, Asokan A, Jarrold MF (July 2016). "Resolving Adeno-Associated Viral Particle Diversity With Charge Detection Mass Spectrometry". Analytical Chemistry. 88 (13). American Chemical Society (ACS): 6718–6725. doi:10.1021/acs.analchem.6b00883. PMC 6537880. PMID 27310298.
Xie Q, Bu W, Bhatia S, Hare J, Somasundaram T, Azzi A, et al. (August 2002). "The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy". Proceedings of the National Academy of Sciences of the United States of America. 99 (16): 10405–10. Bibcode:2002PNAS...9910405X. doi:10.1073/pnas.162250899. PMC 124927. PMID 12136130.
Sonntag F, Köther K, Schmidt K, Weghofer M, Raupp C, Nieto K, et al. (December 2011). "The assembly-activating protein promotes capsid assembly of different adeno-associated virus serotypes". Journal of Virology. 85 (23): 12686–97. doi:10.1128/JVI.05359-11. PMC 3209379. PMID 21917944.
Becerra SP, Rose JA, Hardy M, Baroudy BM, Anderson CW (December 1985). "Direct mapping of adeno-associated virus capsid proteins B and C: a possible ACG initiation codon". Proceedings of the National Academy of Sciences of the United States of America. 82 (23): 7919–23. Bibcode:1985PNAS...82.7919B. doi:10.1073/pnas.82.23.7919. PMC 390881. PMID 2999784.
Muralidhar S, Becerra SP, Rose JA (January 1994). "Site-directed mutagenesis of adeno-associated virus type 2 structural protein initiation codons: effects on regulation of synthesis and biological activity". Journal of Virology. 68 (1): 170–6. doi:10.1128/JVI.68.1.170-176.1994. PMC 236275. PMID 8254726.
Trempe JP, Carter BJ (September 1988). "Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein". Journal of Virology. 62 (9): 3356–63. doi:10.1128/JVI.62.9.3356-3363.1988. PMC 253458. PMID 2841488.
Warrington KH, Gorbatyuk OS, Harrison JK, Opie SR, Zolotukhin S, Muzyczka N (June 2004). "Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus". Journal of Virology. 78 (12): 6595–609. doi:10.1128/JVI.78.12.6595-6609.2004. PMC 416546. PMID 15163751.
Rumachik NG, Malaker SA, Poweleit N, Maynard LH, Adams CM, Leib RD, et al. (May 2020). "Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors". Molecular Therapy – Methods & Clinical Development. 18: 98–118. doi:10.1016/j.omtm.2020.05.018. PMC 7488757. PMID 32995354.
Chen Q, Njenga R, Leuchs B, Chiocca S, Kleinschmidt J, Muller M (September 2020). "SUMOylation Targets Adeno-associated Virus Capsids but Mainly Restricts Transduction by Cellular Mechanisms". Journal of Virology. 94 (19): e00871-20. doi:10.1128/JVI.00871-20. PMC 7495375. PMID 32669341.
Giles AR, Sims JJ, Turner KB, Govindasamy L, Alvira MR, Lock M, et al. (December 2018). "Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function". Molecular Therapy. 26 (12): 2848–2862. doi:10.1016/j.ymthe.2018.09.013. PMC 6277538. PMID 30343890.
Issa SS, Shaimardanova AA, Solovyeva VV, Rizvanov AA (1 March 2023). "Various AAV Serotypes and Their Applications in Gene Therapy: An Overview". Cells. 12 (5): 785. doi:10.3390/cells12050785. PMC 10000783. PMID 36899921.
Wu P, Xiao W, Conlon T, Hughes J, Agbandje-McKenna M, Ferkol T, et al. (September 2000). "Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism". Journal of Virology. 74 (18): 8635–47. doi:10.1128/JVI.74.18.8635-8647.2000. PMC 102071. PMID 10954565.
Koeberl DD, Alexander IE, Halbert CL, Russell DW, Miller AD (February 1997). "Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors". Proceedings of the National Academy of Sciences of the United States of America. 94 (4): 1426–31. Bibcode:1997PNAS...94.1426K. doi:10.1073/pnas.94.4.1426. PMC 19807. PMID 9037069.
Summerford C, Samulski RJ (February 1998). "Membrane-associated heparan sulfate proteo-glycan is a receptor for adeno-associated virus type 2 virions". Journal of Virology. 72 (2): 1438–45. doi:10.1128/JVI.72.2.1438-1445.1998. PMC 124624. PMID 9445046.
Pajusola K, Gruchala M, Joch H, Lüscher TF, Ylä-Herttuala S, Büeler H (November 2002). "Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells". Journal of Virology. 76 (22): 11530–40. doi:10.1128/JVI.76.22.11530-11540.2002. PMC 136795. PMID 12388714.
Limberis MP, Vandenberghe LH, Zhang L, Pickles RJ, Wilson JM (February 2009). "Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro". Molecular Therapy. 17 (2): 294–301. doi:10.1038/mt.2008.261. PMC 2835069. PMID 19066597.
Gao GP, Alvira MR, Wang L, Calcedo R, Johnston J, Wilson JM (September 2002). "Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy". Proceedings of the National Academy of Sciences of the United States of America. 99 (18): 11854–9. Bibcode:2002PNAS...9911854G. doi:10.1073/pnas.182412299. PMC 129358. PMID 12192090.
Halbert CL, Allen JM, Miller AD (July 2001). "Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors". Journal of Virology. 75 (14): 6615–24. doi:10.1128/JVI.75.14.6615-6624.2001. PMC 114385. PMID 11413329.
Rabinowitz JE, Bowles DE, Faust SM, Ledford JG, Cunningham SE, Samulski RJ (May 2004). "Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups". Journal of Virology. 78 (9): 4421–32. doi:10.1128/JVI.78.9.4421-4432.2004. PMC 387689. PMID 15078923.
Chen S, Kapturczak M, Loiler SA, Zolotukhin S, Glushakova OY, Madsen KM, et al. (February 2005). "Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors". Human Gene Therapy. 16 (2): 235–47. doi:10.1089/hum.2005.16.235. PMC 1364465. PMID 15761263.
Ortinski PI, Dong J, Mungenast A, Yue C, Takano H, Watson DJ, et al. (May 2010). "Selective induction of astrocytic gliosis generates deficits in neuronal inhibition". Nature Neuroscience. 13 (5): 584–91. doi:10.1038/nn.2535. PMC 3225960. PMID 20418874.
Kaludov N, Brown KE, Walters RW, Zabner J, Chiorini JA (August 2001). "Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity". Journal of Virology. 75 (15): 6884–93. doi:10.1128/JVI.75.15.6884-6893.2001. PMC 114416. PMID 11435568.
Excoffon, K, et al. (2009). "Directed evolution of adeno-associated virus to an infectious respiratory virus". Proceedings of the National Academy of Sciences. 106 (10): 3865–3870. Bibcode:2009PNAS..106.3865E. doi:10.1073/pnas.0813365106. PMC 2646629. PMID 19237554.
Zinn E, Pacouret S, Khaychuk V, Turunen HT, Carvalho LS, Andres-Mateos E, et al. (August 2015). "In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector". Cell Reports. 12 (6): 1056–68. doi:10.1016/j.celrep.2015.07.019. PMC 4536165. PMID 26235624.
Ronzitti G, Gross DA, Mingozzi F (2020). "Human Immune Responses to Adeno-Associated Virus (AAV) Vectors". Frontiers in Immunology. 11: 670. doi:10.3389/fimmu.2020.00670. PMC 7181373. PMID 32362898.
Vandamme C, Adjali O, Mingozzi F (November 2017). "Unraveling the Complex Story of Immune Responses to AAV Vectors Trial After Trial". Human Gene Therapy. 28 (11): 1061–1074. doi:10.1089/hum.2017.150. PMC 5649404. PMID 28835127.
Barnes C, Scheideler O, Schaffer D (December 2019). "Engineering the AAV capsid to evade immune responses". Current Opinion in Biotechnology. 60: 99–103. doi:10.1016/j.copbio.2019.01.002. PMC 7117822. PMID 30807882.
Zaiss AK, Liu Q, Bowen GP, Wong NC, Bartlett JS, Muruve DA (May 2002). "Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors". Journal of Virology. 76 (9): 4580–90. doi:10.1128/JVI.76.9.4580-4590.2002. PMC 155101. PMID 11932423.
Zhu J, Huang X, Yang Y (August 2009). "The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice". The Journal of Clinical Investigation. 119 (8): 2388–2398. doi:10.1172/JCI37607. PMC 2719948. PMID 19587448.
Martino AT, Suzuki M, Markusic DM, Zolotukhin I, Ryals RC, Moghimi B, et al. (June 2011). "The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver". Blood. 117 (24): 6459–6468. doi:10.1182/blood-2010-10-314518. PMC 3123017. PMID 21474674.
Calcedo R, Morizono H, Wang L, McCarter R, He J, Jones D, et al. (September 2011). "Adeno-associated virus antibody profiles in newborns, children, and adolescents". Clinical and Vaccine Immunology. 18 (9): 1586–1588. doi:10.1128/CVI.05107-11. PMC 3165215. PMID 21775517.
Tse LV, Klinc KA, Madigan VJ, Castellanos Rivera RM, Wells LF, Havlik LP, et al. (June 2017). "Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion". Proceedings of the National Academy of Sciences of the United States of America. 114 (24): E4812 – E4821. Bibcode:2017PNAS..114E4812T. doi:10.1073/pnas.1704766114. PMC 5474820. PMID 28559317.
Madsen D, Cantwell ER, O'Brien T, Johnson PA, Mahon BP (November 2009). "Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1". The Journal of General Virology. 90 (Pt 11): 2622–33. doi:10.1099/vir.0.014175-0. PMC 2885037. PMID 19641045.
Myers MW, Laughlin CA, Jay FT, Carter BJ (July 1980). "Adenovirus helper function for growth of adeno-associated virus: effect of temperature-sensitive mutations in adenovirus early gene region 2". Journal of Virology. 35 (1): 65–75. doi:10.1128/JVI.35.1.65-75.1980. PMC 288783. PMID 6251278.
Yakobson B, Koch T, Winocour E (April 1987). "Replication of adeno-associated virus in synchronized cells without the addition of a helper virus". Journal of Virology. 61 (4): 972–81. doi:10.1128/JVI.61.4.972-981.1987. PMC 254052. PMID 3029431.
Yakobson B, Hrynko TA, Peak MJ, Winocour E (March 1989). "Replication of adeno-associated virus in cells irradiated with UV light at 254 nm". Journal of Virology. 63 (3): 1023–30. doi:10.1128/JVI.63.3.1023-1030.1989. PMC 247794. PMID 2536816.
Duan D, Sharma P, Yang J, Yue Y, Dudus L, Zhang Y, et al. (November 1998). "Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue". Journal of Virology. 72 (11): 8568–77. doi:10.1128/JVI.72.11.8568-8577.1998. PMC 110267. PMID 9765395.

psu.edu

citeseerx.ist.psu.edu

Bainbridge JW, Smith AJ, Barker SS, Robbie S, Henderson R, Balaggan K, et al. (May 2008). "Effect of gene therapy on visual function in Leber's congenital amaurosis". The New England Journal of Medicine. 358 (21): 2231–9. CiteSeerX 10.1.1.574.4003. doi:10.1056/NEJMoa0802268. PMID 18441371.

sciencedaily.com

Penn State (23 June 2005). "Harmless Virus Kills Some Cancers". Science Daily.

semanticscholar.org

api.semanticscholar.org

LeWitt PA, Rezai AR, Leehey MA, Ojemann SG, Flaherty AW, Eskandar EN, et al. (April 2011). "AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial". The Lancet. Neurology. 10 (4): 309–19. doi:10.1016/S1474-4422(11)70039-4. PMID 21419704. S2CID 37154043.
Kaplitt MG, Feigin A, Tang C, Fitzsimons HL, Mattis P, Lawlor PA, et al. (June 2007). "Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial". Lancet. 369 (9579): 2097–105. doi:10.1016/S0140-6736(07)60982-9. PMID 17586305. S2CID 24491886.
Im DS, Muzyczka N (May 1990). "The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity". Cell. 61 (3): 447–57. doi:10.1016/0092-8674(90)90526-K. PMID 2159383. S2CID 27997617.
Richter M, Iwata A, Nyhuis J, Nitta Y, Miller AD, Halbert CL, et al. (April 2000). "Adeno-associated virus vector transduction of vascular smooth muscle cells in vivo". Physiological Genomics. 2 (3): 117–27. doi:10.1152/physiolgenomics.2000.2.3.117. PMID 11015590. S2CID 14150468.
Qing K, Mah C, Hansen J, Zhou S, Dwarki V, Srivastava A (January 1999). "Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2". Nature Medicine. 5 (1): 71–7. doi:10.1038/4758. PMID 9883842. S2CID 31602526.
Summerford C, Bartlett JS, Samulski RJ (January 1999). "AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection". Nature Medicine. 5 (1): 78–82. doi:10.1038/4768. PMID 9883843. S2CID 23326070.
Di Pasquale G, Davidson BL, Stein CS, Martins I, Scudiero D, Monks A, et al. (October 2003). "Identification of PDGFR as a receptor for AAV-5 transduction". Nature Medicine. 9 (10): 1306–12. doi:10.1038/nm929. PMID 14502277. S2CID 32547188.
Manno CS, Pierce GF, Arruda VR, Glader B, Ragni M, Rasko JJ, et al. (March 2006). "Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response". Nature Medicine. 12 (3): 342–7. doi:10.1038/nm1358. PMID 16474400. S2CID 14664182.

uiowa.edu

ehs.research.uiowa.edu

"Adeno-Associated Virus and Adeno-associated Viral Vectors". Environmental Health & Safety. University of Iowa. Archived from the original on 20 September 2018. Retrieved 19 September 2018.

vectorbiolabs.com

"Introduction to Adeno-Associated Virus (AAV)". Vector Biolabs. Malvern, PA.

vectorbuilder.com

en.vectorbuilder.com

"AAV tropisms". VectorBuilder.

web.archive.org

"Vectors used in Gene Therapy Clinical Trials". Journal of Gene Medicine. Wiley. December 2018. Archived from the original on 21 October 2019. Retrieved 4 January 2012.
"AveXis Reports Data from Ongoing Phase 1 Trial of AVXS-101 in Spinal Muscular Atrophy Type 1". Avexis. 6 May 2016. Archived from the original on 11 June 2017. Retrieved 8 May 2016.
"ELEVIDYS". FDA - Approved Gene Therapy Products - ELEVIDYS. 3 January 2025. Archived from the original on 23 June 2023. Retrieved 3 December 2024.
"Adeno-Associated Virus and Adeno-associated Viral Vectors". Environmental Health & Safety. University of Iowa. Archived from the original on 20 September 2018. Retrieved 19 September 2018.

zenodo.org

Di Pasquale G, Davidson BL, Stein CS, Martins I, Scudiero D, Monks A, et al. (October 2003). "Identification of PDGFR as a receptor for AAV-5 transduction". Nature Medicine. 9 (10): 1306–12. doi:10.1038/nm929. PMID 14502277. S2CID 32547188.