Akt/PKB signaling pathway (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Akt/PKB signaling pathway" in English language version.

refsWebsite

Global rank English rank

70nih.gov

4^th place

46doi.org

2^nd place

5harvard.edu

18^th place

17^th place

4semanticscholar.org

11^th place

8^th place

1retractionwatch.com

low place

1bjbms.org

low place

bjbms.org

Wu Q, Qi B, Duan X, Ming X, Yan F, He Y, Bu X, Sun S, Zhu H. MicroRNA-126 enhances the biological function of endothelial progenitor cells under oxidative stress via PI3K/Akt/GSK-3β and ERK1/2 signaling pathways. Bosn J of Basic Med Sci [Internet]. 2020Jan.30 [cited 2020Mar.14];. Available from: https://www.bjbms.org/ojs/index.php/bjbms/article/view/4493

doi.org

Osaki M, Oshimura M, Ito H (2004). "The PI3K-Akt pathway: Its functions and alterations in human cancer". Apoptosis. 9 (6): 667–676. doi:10.1023/B:APPT.0000045801.15585.dd. PMID 15505410. S2CID 13346655.
Manning BD, Cantley LC (2007). "AKT/PKB Signaling: Navigating Downstream". Cell. 129 (7): 1261–1274. doi:10.1016/j.cell.2007.06.009. PMC 2756685. PMID 17604717.
Carracedo A, Pandolfi PP (2008). "The PTEN-PI3K pathway: of feedbacks and cross-talks". Oncogene. 27 (41): 5527–5541. doi:10.1038/onc.2008.247. PMID 18794886.
Cantrell DA (2001). "Phosphoinositide 3-kinase signalling pathways". J Cell Sci. 114 (Pt 8): 1439–1445. doi:10.1242/jcs.114.8.1439. PMID 11282020.
Nicholson KM, Anderson NG (2002). "The protein kinase B/Akt signalling pathway in human malignancy". Cellular Signalling. 14 (5): 381–395. doi:10.1016/S0898-6568(01)00271-6. PMID 11882383.
Castellano E, Downward J (2011). "RAS Interaction with PI3K". Genes Cancer. 2 (3): 261–74. doi:10.1177/1947601911408079. PMC 3128635. PMID 21779497.
Hemmings BA, Restuccia DF (2012). "PI3K-PKB/Akt Pathway". Cold Spring Harb Perspect Biol. 4 (9): a011189. doi:10.1101/cshperspect.a011189. PMC 3428770. PMID 22952397.
New DC, Wong YH (2007). "Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression". J Mol Signall. 2 (2): 2. doi:10.1186/1750-2187-2-2. PMC 1808056. PMID 17319972.
Fruman DA, Meyers RE, Cantley LC (1998). "Phosphoinositide Kinases". Annu Rev Biochem. 67: 481–507. doi:10.1146/annurev.biochem.67.1.481. PMID 9759495.
Cantley LC (2002). "The Phosphoinositide 3-Kinase Pathway". Science. 296 (5573): 1655–1657. Bibcode:2002Sci...296.1655C. doi:10.1126/science.296.5573.1655. PMID 12040186.
Miao B, Skidan I, Yang J, Lugovskoy A, Reibarkh M, Long K, Brazell T, Durugkar KA, Maki J, Ramana CV, Schaffhausen B, Wagner G, Torchilin V, Yuan J, Degterev A (2010). "Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains". Proc. Natl. Acad. Sci. USA. 107 (46): 20126–20131. Bibcode:2010PNAS..10720126M. doi:10.1073/pnas.1004522107. PMC 2993381. PMID 21041639.
Ballesteros-Álvarez J, Andersen JK (August 2021). "mTORC2: The other mTOR in autophagy regulation". Aging Cell. 20 (8): e13431. doi:10.1111/acel.13431. PMC 8373318. PMID 34250734.
Vanhaesebroeck B, Alessi DR (March 2000). "The PI3K-PDK1 connection: more than just a road to PKB". The Biochemical Journal. 346 (3): 561–76. doi:10.1042/0264-6021:3460561. PMC 1220886. PMID 10698680.
Mahajan K, Mahajan NP (September 2012). "PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics". Journal of Cellular Physiology. 227 (9): 3178–84. doi:10.1002/jcp.24065. PMC 3358464. PMID 22307544.
Shaw M, Cohen P, Alessi DR (November 1998). "The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2". The Biochemical Journal. 336 (1): 241–6. doi:10.1042/bj3360241. PMC 1219864. PMID 9806907.
Soderling TR (June 1999). "The Ca-calmodulin-dependent protein kinase cascade". Trends in Biochemical Sciences. 24 (6): 232–6. doi:10.1016/S0968-0004(99)01383-3. PMID 10366852.
Mahajan K, Mahajam NP (2010). "Shepherding AKT and androgen receptor by Ack1 tyrosine kinase". J Cell Physiol. 224 (2): 327–33. doi:10.1002/jcp.22162. PMC 3953130. PMID 20432460.
Jiang T, Qiu Y (May 2003). "Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation". The Journal of Biological Chemistry. 278 (18): 15789–93. doi:10.1074/jbc.M212525200. PMID 12600984.
Zheng Y, Peng M, Wang Z, Asara JM, Tyner AL (2010). "Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor". Mol Cell Biol. 30 (17): 4280–92. doi:10.1128/MCB.00024-10. PMC 2937549. PMID 20606012.
Guo JP, Coppola D, Cheng JQ (2011). "IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation". J Biol Chem. 286 (43): 37389–98. doi:10.1074/jbc.M111.287433. PMC 3199486. PMID 21908616. (Retracted, see doi:10.1074/jbc.A111.287433, PMID 27825091, Retraction Watch. If this is an intentional citation to a retracted paper, please replace {{retracted|...}} with {{retracted|...|intentional=yes}}.)
Joung SM, Park ZY, Rani S, Takeuchi O, Akira S, Lee JY (2011). "Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1". J Immunol. 186 (1): 499–507. doi:10.4049/jimmunol.0903534. PMID 21106850.
Toulany M, Rodemann HP (2013). "Potential of Akt mediated DNA repair in radioresistance of solid tumors overexpressing erbB-PI3K-Akt pathway". Translational Cancer Research. 2 (3). doi:10.3978/j.issn.2218-676X.2013.04.09.
Georgescu MM (December 2010). "PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control". Genes & Cancer. 1 (12): 1170–7. doi:10.1177/1947601911407325. PMC 3092286. PMID 21779440.
Wang X, Trotman LC, Koppie T, Alimonti A, Chen Z, Gao Z, et al. (January 2007). "NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN". Cell. 128 (1): 129–39. doi:10.1016/j.cell.2006.11.039. PMC 1828909. PMID 17218260.
Zhang J, Gao Z, Yin J, Quon MJ, Ye J (2008). "S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2". J Biol Chem. 283 (51): 35375–82. doi:10.1074/jbc.M806480200. PMC 2602883. PMID 18952604.
Song G, Ouyang G, Bao S (2005). "The activation of Akt/PKB signalling pathway and cell survival". J Cell Mol Med. 9 (1): 59–71. doi:10.1111/j.1582-4934.2005.tb00337.x. PMC 6741304. PMID 15784165.
Zhang X, Tang N, Hadden TJ, Rishi AK (2011). "Akt, FoxO and regulation of apoptosis". Biochim Biophys Acta. 1813 (11): 1978–1986. doi:10.1016/j.bbamcr.2011.03.010. PMID 21440011.
Du K, Montminy M (1998). "CREB Is a Regulatory Target for the Protein Kinase Akt/PKB". J Biol Chem. 273 (49): 32377–32379. doi:10.1074/jbc.273.49.32377. PMID 9829964.
Basu S, Totty NF, Irwin MS, Sudol M, Downward J (2003). "Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis". Mol Cell. 11 (1): 11–23. doi:10.1016/S1097-2765(02)00776-1. PMID 12535517.
Sardiello M, Palmieri M, di Ronza A, Medina DL, Valenza M, Gennarino VA, Di Malta C, Donaudy F, Embrione V, Polishchuk RS, Banfi S, Parenti G, Cattaneo E, Ballabio A (Jul 2009). "A gene network regulating lysosomal biogenesis and function". Science. 325 (5939): 473–7. Bibcode:2009Sci...325..473S. doi:10.1126/science.1174447. PMID 19556463. S2CID 20353685.
Palmieri M, Pal R, Nelvagal HR, Lotfi P, Stinnett GR, Seymour ML, Chaudhury A, Bajaj L, Bondar VV, Bremner L, Saleem U, Tse DY, Sanagasetti D, Wu SM, Neilson JR, Pereira FA, Pautler RG, Rodney GG, Cooper JD, Sardiello M (Feb 2017). "mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases". Nature Communications. 8: 14338. Bibcode:2017NatCo...814338P. doi:10.1038/ncomms14338. PMC 5303831. PMID 28165011.
Alao JP (April 2007). "The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention". Molecular Cancer. 6 (24): 24. doi:10.1186/1476-4598-6-24. PMC 1851974. PMID 17407548.
Hay N, Sonenberg N (2004). "Upstream and downstream of mTOR". Genes Dev. 18 (16): 1926–45. doi:10.1101/gad.1212704. PMID 15314020.
Denicourt C, Dowdy S (2004). "Cip/Kip proteins: more than just CDKs inhibitors". Genes Dev. 18 (8): 851–855. doi:10.1101/gad.1205304. PMID 15107401.
Li Y, Dowbenko D, Lasky LA (2001). "AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival". J Biol Chem. 277 (13): 11352–11361. doi:10.1074/jbc.M109062200. PMID 11756412.
Liang J, Slingerland JM (2003). "Multiple Roles of the PI3K/PKB (Akt) Pathway in Cell Cycle Progression". Cell Cycle. 2 (4): 336–342. doi:10.4161/cc.2.4.433. PMID 12851486.
Xue G, Hemmings BA (2013). "PKB/Akt-Dependent Regulation of Cell Motility". J Natl Cancer Inst. 105 (6): 393–404. doi:10.1093/jnci/djs648. PMID 23355761.
Enomoto A, Ping J, Takahashi M (2006). "Girdin, a novel actin-binding protein, and its family of proteins possess versatile functions in the Akt and Wnt signaling pathways". Ann N Y Acad Sci. 1086 (1): 169–184. Bibcode:2006NYASA1086..169E. doi:10.1196/annals.1377.016. PMID 17185515. S2CID 6296664.
Meima ME, Webb BA, Witkowska HE, Barber DL (2009). "The Sodium-Hydrogen Exchanger NHE1 Is an Akt Substrate Necessary for Actin Filament Reorganization by Growth Factors". J Biol Chem. 284 (39): 26666–26675. doi:10.1074/jbc.M109.019448. PMC 2785354. PMID 19622752.
Ravid D, Chuderland D, Landsman L, Lavie Y, Reich R, Liscovitch M (2008). "Filamin A is a novel caveolin-1-dependent target in IGF-I-stimulated cancer cell migration". Exp Cell Res. 314 (15): 2762–2773. doi:10.1016/j.yexcr.2008.06.004. PMID 18598695.
Kakinuma N, Roy BC, Zhu Y, Wang Y, Kiyama R (2008). "Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K–Akt signaling". J Cell Biol. 181 (3): 537–549. doi:10.1083/jcb.200707022. PMC 2364698. PMID 18458160.
Inoki K, Li Y, Zhu T, Wu J, Guan KL (2002). "TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling". Nat Cell Biol. 4 (9): 648–657. doi:10.1038/ncb839. PMID 12172553. S2CID 11880801.
Chin YR, Toker A (2010). "Akt2 regulates expression of the actin-bundling protein palladin". FEBS Lett. 584 (23): 4769–4774. doi:10.1016/j.febslet.2010.10.056. PMC 2997733. PMID 21050850.
Lamalice L, Le Boeuf F, Huot J (2007). "Endothelial Cell Migration During Angiogenesis". Circulation Research. 100 (6): 782–794. doi:10.1161/01.RES.0000259593.07661.1e. PMID 17395884.
Yuan TL, Cantley LC (September 2008). "PI3K pathway alterations in cancer: variations on a theme". Oncogene. 27 (41): 5497–510. doi:10.1038/onc.2008.245. PMC 3398461. PMID 18794884.
Karar J, Maity A (2011). "PI3K/AKT/mTOR Pathway in Angiogenesis". Front Mol Neurosci. 4 (51): 51. doi:10.3389/fnmol.2011.00051. PMC 3228996. PMID 22144946.

harvard.edu

ui.adsabs.harvard.edu

Cantley LC (2002). "The Phosphoinositide 3-Kinase Pathway". Science. 296 (5573): 1655–1657. Bibcode:2002Sci...296.1655C. doi:10.1126/science.296.5573.1655. PMID 12040186.
Miao B, Skidan I, Yang J, Lugovskoy A, Reibarkh M, Long K, Brazell T, Durugkar KA, Maki J, Ramana CV, Schaffhausen B, Wagner G, Torchilin V, Yuan J, Degterev A (2010). "Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains". Proc. Natl. Acad. Sci. USA. 107 (46): 20126–20131. Bibcode:2010PNAS..10720126M. doi:10.1073/pnas.1004522107. PMC 2993381. PMID 21041639.
Sardiello M, Palmieri M, di Ronza A, Medina DL, Valenza M, Gennarino VA, Di Malta C, Donaudy F, Embrione V, Polishchuk RS, Banfi S, Parenti G, Cattaneo E, Ballabio A (Jul 2009). "A gene network regulating lysosomal biogenesis and function". Science. 325 (5939): 473–7. Bibcode:2009Sci...325..473S. doi:10.1126/science.1174447. PMID 19556463. S2CID 20353685.
Palmieri M, Pal R, Nelvagal HR, Lotfi P, Stinnett GR, Seymour ML, Chaudhury A, Bajaj L, Bondar VV, Bremner L, Saleem U, Tse DY, Sanagasetti D, Wu SM, Neilson JR, Pereira FA, Pautler RG, Rodney GG, Cooper JD, Sardiello M (Feb 2017). "mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases". Nature Communications. 8: 14338. Bibcode:2017NatCo...814338P. doi:10.1038/ncomms14338. PMC 5303831. PMID 28165011.
Enomoto A, Ping J, Takahashi M (2006). "Girdin, a novel actin-binding protein, and its family of proteins possess versatile functions in the Akt and Wnt signaling pathways". Ann N Y Acad Sci. 1086 (1): 169–184. Bibcode:2006NYASA1086..169E. doi:10.1196/annals.1377.016. PMID 17185515. S2CID 6296664.

nih.gov

pubmed.ncbi.nlm.nih.gov

Osaki M, Oshimura M, Ito H (2004). "The PI3K-Akt pathway: Its functions and alterations in human cancer". Apoptosis. 9 (6): 667–676. doi:10.1023/B:APPT.0000045801.15585.dd. PMID 15505410. S2CID 13346655.
Manning BD, Cantley LC (2007). "AKT/PKB Signaling: Navigating Downstream". Cell. 129 (7): 1261–1274. doi:10.1016/j.cell.2007.06.009. PMC 2756685. PMID 17604717.
Carracedo A, Pandolfi PP (2008). "The PTEN-PI3K pathway: of feedbacks and cross-talks". Oncogene. 27 (41): 5527–5541. doi:10.1038/onc.2008.247. PMID 18794886.
Cantrell DA (2001). "Phosphoinositide 3-kinase signalling pathways". J Cell Sci. 114 (Pt 8): 1439–1445. doi:10.1242/jcs.114.8.1439. PMID 11282020.
Nicholson KM, Anderson NG (2002). "The protein kinase B/Akt signalling pathway in human malignancy". Cellular Signalling. 14 (5): 381–395. doi:10.1016/S0898-6568(01)00271-6. PMID 11882383.
Castellano E, Downward J (2011). "RAS Interaction with PI3K". Genes Cancer. 2 (3): 261–74. doi:10.1177/1947601911408079. PMC 3128635. PMID 21779497.
Hemmings BA, Restuccia DF (2012). "PI3K-PKB/Akt Pathway". Cold Spring Harb Perspect Biol. 4 (9): a011189. doi:10.1101/cshperspect.a011189. PMC 3428770. PMID 22952397.
New DC, Wong YH (2007). "Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression". J Mol Signall. 2 (2): 2. doi:10.1186/1750-2187-2-2. PMC 1808056. PMID 17319972.
Fruman DA, Meyers RE, Cantley LC (1998). "Phosphoinositide Kinases". Annu Rev Biochem. 67: 481–507. doi:10.1146/annurev.biochem.67.1.481. PMID 9759495.
Cantley LC (2002). "The Phosphoinositide 3-Kinase Pathway". Science. 296 (5573): 1655–1657. Bibcode:2002Sci...296.1655C. doi:10.1126/science.296.5573.1655. PMID 12040186.
Miao B, Skidan I, Yang J, Lugovskoy A, Reibarkh M, Long K, Brazell T, Durugkar KA, Maki J, Ramana CV, Schaffhausen B, Wagner G, Torchilin V, Yuan J, Degterev A (2010). "Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains". Proc. Natl. Acad. Sci. USA. 107 (46): 20126–20131. Bibcode:2010PNAS..10720126M. doi:10.1073/pnas.1004522107. PMC 2993381. PMID 21041639.
Ballesteros-Álvarez J, Andersen JK (August 2021). "mTORC2: The other mTOR in autophagy regulation". Aging Cell. 20 (8): e13431. doi:10.1111/acel.13431. PMC 8373318. PMID 34250734.
Vanhaesebroeck B, Alessi DR (March 2000). "The PI3K-PDK1 connection: more than just a road to PKB". The Biochemical Journal. 346 (3): 561–76. doi:10.1042/0264-6021:3460561. PMC 1220886. PMID 10698680.
Mahajan K, Mahajan NP (September 2012). "PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics". Journal of Cellular Physiology. 227 (9): 3178–84. doi:10.1002/jcp.24065. PMC 3358464. PMID 22307544.
Shaw M, Cohen P, Alessi DR (November 1998). "The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2". The Biochemical Journal. 336 (1): 241–6. doi:10.1042/bj3360241. PMC 1219864. PMID 9806907.
Soderling TR (June 1999). "The Ca-calmodulin-dependent protein kinase cascade". Trends in Biochemical Sciences. 24 (6): 232–6. doi:10.1016/S0968-0004(99)01383-3. PMID 10366852.
Mahajan K, Mahajam NP (2010). "Shepherding AKT and androgen receptor by Ack1 tyrosine kinase". J Cell Physiol. 224 (2): 327–33. doi:10.1002/jcp.22162. PMC 3953130. PMID 20432460.
Jiang T, Qiu Y (May 2003). "Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation". The Journal of Biological Chemistry. 278 (18): 15789–93. doi:10.1074/jbc.M212525200. PMID 12600984.
Zheng Y, Peng M, Wang Z, Asara JM, Tyner AL (2010). "Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor". Mol Cell Biol. 30 (17): 4280–92. doi:10.1128/MCB.00024-10. PMC 2937549. PMID 20606012.
Guo JP, Coppola D, Cheng JQ (2011). "IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation". J Biol Chem. 286 (43): 37389–98. doi:10.1074/jbc.M111.287433. PMC 3199486. PMID 21908616. (Retracted, see doi:10.1074/jbc.A111.287433, PMID 27825091, Retraction Watch. If this is an intentional citation to a retracted paper, please replace {{retracted|...}} with {{retracted|...|intentional=yes}}.)
Joung SM, Park ZY, Rani S, Takeuchi O, Akira S, Lee JY (2011). "Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1". J Immunol. 186 (1): 499–507. doi:10.4049/jimmunol.0903534. PMID 21106850.
Georgescu MM (December 2010). "PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control". Genes & Cancer. 1 (12): 1170–7. doi:10.1177/1947601911407325. PMC 3092286. PMID 21779440.
Wang X, Trotman LC, Koppie T, Alimonti A, Chen Z, Gao Z, et al. (January 2007). "NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN". Cell. 128 (1): 129–39. doi:10.1016/j.cell.2006.11.039. PMC 1828909. PMID 17218260.
Zhang J, Gao Z, Yin J, Quon MJ, Ye J (2008). "S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2". J Biol Chem. 283 (51): 35375–82. doi:10.1074/jbc.M806480200. PMC 2602883. PMID 18952604.
Song G, Ouyang G, Bao S (2005). "The activation of Akt/PKB signalling pathway and cell survival". J Cell Mol Med. 9 (1): 59–71. doi:10.1111/j.1582-4934.2005.tb00337.x. PMC 6741304. PMID 15784165.
Zhang X, Tang N, Hadden TJ, Rishi AK (2011). "Akt, FoxO and regulation of apoptosis". Biochim Biophys Acta. 1813 (11): 1978–1986. doi:10.1016/j.bbamcr.2011.03.010. PMID 21440011.
Du K, Montminy M (1998). "CREB Is a Regulatory Target for the Protein Kinase Akt/PKB". J Biol Chem. 273 (49): 32377–32379. doi:10.1074/jbc.273.49.32377. PMID 9829964.
Basu S, Totty NF, Irwin MS, Sudol M, Downward J (2003). "Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis". Mol Cell. 11 (1): 11–23. doi:10.1016/S1097-2765(02)00776-1. PMID 12535517.
Sardiello M, Palmieri M, di Ronza A, Medina DL, Valenza M, Gennarino VA, Di Malta C, Donaudy F, Embrione V, Polishchuk RS, Banfi S, Parenti G, Cattaneo E, Ballabio A (Jul 2009). "A gene network regulating lysosomal biogenesis and function". Science. 325 (5939): 473–7. Bibcode:2009Sci...325..473S. doi:10.1126/science.1174447. PMID 19556463. S2CID 20353685.
Palmieri M, Pal R, Nelvagal HR, Lotfi P, Stinnett GR, Seymour ML, Chaudhury A, Bajaj L, Bondar VV, Bremner L, Saleem U, Tse DY, Sanagasetti D, Wu SM, Neilson JR, Pereira FA, Pautler RG, Rodney GG, Cooper JD, Sardiello M (Feb 2017). "mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases". Nature Communications. 8: 14338. Bibcode:2017NatCo...814338P. doi:10.1038/ncomms14338. PMC 5303831. PMID 28165011.
Alao JP (April 2007). "The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention". Molecular Cancer. 6 (24): 24. doi:10.1186/1476-4598-6-24. PMC 1851974. PMID 17407548.
Hay N, Sonenberg N (2004). "Upstream and downstream of mTOR". Genes Dev. 18 (16): 1926–45. doi:10.1101/gad.1212704. PMID 15314020.
Denicourt C, Dowdy S (2004). "Cip/Kip proteins: more than just CDKs inhibitors". Genes Dev. 18 (8): 851–855. doi:10.1101/gad.1205304. PMID 15107401.
Li Y, Dowbenko D, Lasky LA (2001). "AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival". J Biol Chem. 277 (13): 11352–11361. doi:10.1074/jbc.M109062200. PMID 11756412.
Liang J, Slingerland JM (2003). "Multiple Roles of the PI3K/PKB (Akt) Pathway in Cell Cycle Progression". Cell Cycle. 2 (4): 336–342. doi:10.4161/cc.2.4.433. PMID 12851486.
Xue G, Hemmings BA (2013). "PKB/Akt-Dependent Regulation of Cell Motility". J Natl Cancer Inst. 105 (6): 393–404. doi:10.1093/jnci/djs648. PMID 23355761.
Enomoto A, Ping J, Takahashi M (2006). "Girdin, a novel actin-binding protein, and its family of proteins possess versatile functions in the Akt and Wnt signaling pathways". Ann N Y Acad Sci. 1086 (1): 169–184. Bibcode:2006NYASA1086..169E. doi:10.1196/annals.1377.016. PMID 17185515. S2CID 6296664.
Meima ME, Webb BA, Witkowska HE, Barber DL (2009). "The Sodium-Hydrogen Exchanger NHE1 Is an Akt Substrate Necessary for Actin Filament Reorganization by Growth Factors". J Biol Chem. 284 (39): 26666–26675. doi:10.1074/jbc.M109.019448. PMC 2785354. PMID 19622752.
Ravid D, Chuderland D, Landsman L, Lavie Y, Reich R, Liscovitch M (2008). "Filamin A is a novel caveolin-1-dependent target in IGF-I-stimulated cancer cell migration". Exp Cell Res. 314 (15): 2762–2773. doi:10.1016/j.yexcr.2008.06.004. PMID 18598695.
Kakinuma N, Roy BC, Zhu Y, Wang Y, Kiyama R (2008). "Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K–Akt signaling". J Cell Biol. 181 (3): 537–549. doi:10.1083/jcb.200707022. PMC 2364698. PMID 18458160.
Inoki K, Li Y, Zhu T, Wu J, Guan KL (2002). "TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling". Nat Cell Biol. 4 (9): 648–657. doi:10.1038/ncb839. PMID 12172553. S2CID 11880801.
Chin YR, Toker A (2010). "Akt2 regulates expression of the actin-bundling protein palladin". FEBS Lett. 584 (23): 4769–4774. doi:10.1016/j.febslet.2010.10.056. PMC 2997733. PMID 21050850.
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Liu W, Shen SM, Zhao XY, Chen GQ (2012). "Targeted genes and interacting proteins of hypoxia inducible factor-1". Int J Biochem Mol Biol. 3 (2): 165–178. PMC 3388736. PMID 22773957.

ncbi.nlm.nih.gov

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retractionwatch.com

Guo JP, Coppola D, Cheng JQ (2011). "IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation". J Biol Chem. 286 (43): 37389–98. doi:10.1074/jbc.M111.287433. PMC 3199486. PMID 21908616. (Retracted, see doi:10.1074/jbc.A111.287433, PMID 27825091, Retraction Watch. If this is an intentional citation to a retracted paper, please replace {{retracted|...}} with {{retracted|...|intentional=yes}}.)

semanticscholar.org

api.semanticscholar.org

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