Angiotensin-converting enzyme (English Wikipedia)

Klabunde RE. "ACE-inhibitors". Cardiovascular Pharmacology Concepts. cvpharmacology.com. Archived from the original on 2 February 2009. Retrieved 26 March 2009.

doi.org

Kaplan's Essentials of Cardiac Anesthesia. Elsevier. 2018. doi:10.1016/c2012-0-06151-0. ISBN 978-0-323-49798-5. Mechanisms of Action:ACE inhibitors act by inhibiting one of several proteases responsible for cleaving the decapeptide Ang I to form the octapeptide Ang II. Because ACE is also the enzyme that degrades bradykinin, ACE inhibitors increase circulating and tissue levels of bradykinin (Fig. 8.4).
Dicpinigaitis PV (January 2006). "Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines". Chest. 129 (1 Suppl): 169S – 173S. doi:10.1378/chest.129.1_suppl.169S. PMID 16428706.
Hemming ML, Selkoe DJ (November 2005). "Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor". The Journal of Biological Chemistry. 280 (45): 37644–37650. doi:10.1074/jbc.M508460200. PMC 2409196. PMID 16154999.
Coates D (June 2003). "The angiotensin converting enzyme (ACE)". The International Journal of Biochemistry & Cell Biology. Renin–Angiotensin Systems: State of the Art. 35 (6): 769–773. doi:10.1016/S1357-2725(02)00309-6. PMID 12676162.
Zhang R, Xu X, Chen T, Li L, Rao P (May 2000). "An assay for angiotensin-converting enzyme using capillary zone electrophoresis". Analytical Biochemistry. 280 (2): 286–290. doi:10.1006/abio.2000.4535. PMID 10790312.
Imig JD (March 2004). "ACE Inhibition and Bradykinin-Mediated Renal Vascular Responses: EDHF Involvement". Hypertension. 43 (3): 533–535. doi:10.1161/01.HYP.0000118054.86193.ce. PMID 14757781.
Wang W, McKinnie SM, Farhan M, Paul M, McDonald T, McLean B, et al. (August 2016). "Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17: Physiological Effects in the Cardiovascular System". Hypertension. 68 (2): 365–377. doi:10.1161/HYPERTENSIONAHA.115.06892. PMID 27217402. S2CID 829514.
Bünning P, Riordan JF (July 1985). "The functional role of zinc in angiotensin converting enzyme: implications for the enzyme mechanism". Journal of Inorganic Biochemistry. 24 (3): 183–198. doi:10.1016/0162-0134(85)85002-9. PMID 2995578.
Natesh R, Schwager SL, Sturrock ED, Acharya KR (January 2003). "Crystal structure of the human angiotensin-converting enzyme-lisinopril complex". Nature. 421 (6922): 551–554. Bibcode:2003Natur.421..551N. doi:10.1038/nature01370. PMID 12540854. S2CID 4137382. Archived from the original on 26 November 2022. Retrieved 22 May 2020.
Zhang C, Wu S, Xu D (June 2013). "Catalytic mechanism of angiotensin-converting enzyme and effects of the chloride ion". The Journal of Physical Chemistry B. 117 (22): 6635–6645. doi:10.1021/jp400974n. PMID 23672666.
Bünning P (1983). "The catalytic mechanism of angiotensin converting enzyme". Clinical and Experimental Hypertension. Part A, Theory and Practice. 5 (7–8): 1263–1275. doi:10.3109/10641968309048856. PMID 6315268.
Qiu WQ, Mwamburi M, Besser LM, Zhu H, Li H, Wallack M, et al. (1 January 2013). "Angiotensin converting enzyme inhibitors and the reduced risk of Alzheimer's disease in the absence of apolipoprotein E4 allele". Journal of Alzheimer's Disease. 37 (2): 421–428. doi:10.3233/JAD-130716. PMC 3972060. PMID 23948883.
Delanghe JR, Speeckaert MM, De Buyzere ML (June 2020). "The host's angiotensin-converting enzyme polymorphism may explain epidemiological findings in COVID-19 infections". Clinica Chimica Acta; International Journal of Clinical Chemistry. 505: 192–193. doi:10.1016/j.cca.2020.03.031. PMC 7102561. PMID 32220422.
Cintra MT, Balarin MA, Tanaka SC, Silva VI, Marqui AB, Resende EA, et al. (November 2018). "Polycystic ovarian syndrome: rs1799752 polymorphism of ACE gene". Revista da Associação Médica Brasileira. 64 (11): 1017–1022. doi:10.1590/1806-9282.64.11.1017. PMID 30570054.
Flück M, Kramer M, Fitze DP, Kasper S, Franchi MV, Valdivieso P (8 May 2019). "Cellular Aspects of Muscle Specialization Demonstrate Genotype - Phenotype Interaction Effects in Athletes". Frontiers in Physiology. 10: 526. doi:10.3389/fphys.2019.00526. PMC 6518954. PMID 31139091.
Wang P, Fedoruk MN, Rupert JL (2008). "Keeping pace with ACE: are ACE inhibitors and angiotensin II type 1 receptor antagonists potential doping agents?". Sports Medicine. 38 (12): 1065–1079. doi:10.2165/00007256-200838120-00008. PMID 19026021. S2CID 7614657.
Montgomery HE, Clarkson P, Dollery CM, Prasad K, Losi MA, Hemingway H, et al. (August 1997). "Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training". Circulation. 96 (3): 741–747. doi:10.1161/01.CIR.96.3.741. PMID 9264477.
Costa AM, Silva AJ, Garrido ND, Louro H, de Oliveira RJ, Breitenfeld L (August 2009). "Association between ACE D allele and elite short distance swimming". European Journal of Applied Physiology. 106 (6): 785–790. doi:10.1007/s00421-009-1080-z. hdl:10400.15/3565. PMID 19458960. S2CID 21167767.
Skeggs LT, Kahn JR, Shumway NP (March 1956). "The preparation and function of the hypertensin-converting enzyme". The Journal of Experimental Medicine. 103 (3): 295–299. doi:10.1084/jem.103.3.295. PMC 2136590. PMID 13295487.

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000159640 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000020681 – Ensembl, May 2017

handle.net

hdl.handle.net

Costa AM, Silva AJ, Garrido ND, Louro H, de Oliveira RJ, Breitenfeld L (August 2009). "Association between ACE D allele and elite short distance swimming". European Journal of Applied Physiology. 106 (6): 785–790. doi:10.1007/s00421-009-1080-z. hdl:10400.15/3565. PMID 19458960. S2CID 21167767.

harvard.edu

ui.adsabs.harvard.edu

Natesh R, Schwager SL, Sturrock ED, Acharya KR (January 2003). "Crystal structure of the human angiotensin-converting enzyme-lisinopril complex". Nature. 421 (6922): 551–554. Bibcode:2003Natur.421..551N. doi:10.1038/nature01370. PMID 12540854. S2CID 4137382. Archived from the original on 26 November 2022. Retrieved 22 May 2020.

medscape.org

"The Importance of Treating the Blood Pressure: ACE Inhibitors May Slow Alzheimer's Disease". Medscape. Medscape Cardiology. 2004. Archived from the original on 31 August 2016. Retrieved 1 March 2016.

nih.gov

pubmed.ncbi.nlm.nih.gov

Dicpinigaitis PV (January 2006). "Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines". Chest. 129 (1 Suppl): 169S – 173S. doi:10.1378/chest.129.1_suppl.169S. PMID 16428706.
Hemming ML, Selkoe DJ (November 2005). "Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor". The Journal of Biological Chemistry. 280 (45): 37644–37650. doi:10.1074/jbc.M508460200. PMC 2409196. PMID 16154999.
Coates D (June 2003). "The angiotensin converting enzyme (ACE)". The International Journal of Biochemistry & Cell Biology. Renin–Angiotensin Systems: State of the Art. 35 (6): 769–773. doi:10.1016/S1357-2725(02)00309-6. PMID 12676162.
Zhang R, Xu X, Chen T, Li L, Rao P (May 2000). "An assay for angiotensin-converting enzyme using capillary zone electrophoresis". Analytical Biochemistry. 280 (2): 286–290. doi:10.1006/abio.2000.4535. PMID 10790312.
Imig JD (March 2004). "ACE Inhibition and Bradykinin-Mediated Renal Vascular Responses: EDHF Involvement". Hypertension. 43 (3): 533–535. doi:10.1161/01.HYP.0000118054.86193.ce. PMID 14757781.
Wang W, McKinnie SM, Farhan M, Paul M, McDonald T, McLean B, et al. (August 2016). "Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17: Physiological Effects in the Cardiovascular System". Hypertension. 68 (2): 365–377. doi:10.1161/HYPERTENSIONAHA.115.06892. PMID 27217402. S2CID 829514.
Bünning P, Riordan JF (July 1985). "The functional role of zinc in angiotensin converting enzyme: implications for the enzyme mechanism". Journal of Inorganic Biochemistry. 24 (3): 183–198. doi:10.1016/0162-0134(85)85002-9. PMID 2995578.
Natesh R, Schwager SL, Sturrock ED, Acharya KR (January 2003). "Crystal structure of the human angiotensin-converting enzyme-lisinopril complex". Nature. 421 (6922): 551–554. Bibcode:2003Natur.421..551N. doi:10.1038/nature01370. PMID 12540854. S2CID 4137382. Archived from the original on 26 November 2022. Retrieved 22 May 2020.
Zhang C, Wu S, Xu D (June 2013). "Catalytic mechanism of angiotensin-converting enzyme and effects of the chloride ion". The Journal of Physical Chemistry B. 117 (22): 6635–6645. doi:10.1021/jp400974n. PMID 23672666.
Bünning P (1983). "The catalytic mechanism of angiotensin converting enzyme". Clinical and Experimental Hypertension. Part A, Theory and Practice. 5 (7–8): 1263–1275. doi:10.3109/10641968309048856. PMID 6315268.
Qiu WQ, Mwamburi M, Besser LM, Zhu H, Li H, Wallack M, et al. (1 January 2013). "Angiotensin converting enzyme inhibitors and the reduced risk of Alzheimer's disease in the absence of apolipoprotein E4 allele". Journal of Alzheimer's Disease. 37 (2): 421–428. doi:10.3233/JAD-130716. PMC 3972060. PMID 23948883.
Delanghe JR, Speeckaert MM, De Buyzere ML (June 2020). "The host's angiotensin-converting enzyme polymorphism may explain epidemiological findings in COVID-19 infections". Clinica Chimica Acta; International Journal of Clinical Chemistry. 505: 192–193. doi:10.1016/j.cca.2020.03.031. PMC 7102561. PMID 32220422.
Cintra MT, Balarin MA, Tanaka SC, Silva VI, Marqui AB, Resende EA, et al. (November 2018). "Polycystic ovarian syndrome: rs1799752 polymorphism of ACE gene". Revista da Associação Médica Brasileira. 64 (11): 1017–1022. doi:10.1590/1806-9282.64.11.1017. PMID 30570054.
Flück M, Kramer M, Fitze DP, Kasper S, Franchi MV, Valdivieso P (8 May 2019). "Cellular Aspects of Muscle Specialization Demonstrate Genotype - Phenotype Interaction Effects in Athletes". Frontiers in Physiology. 10: 526. doi:10.3389/fphys.2019.00526. PMC 6518954. PMID 31139091.
Wang P, Fedoruk MN, Rupert JL (2008). "Keeping pace with ACE: are ACE inhibitors and angiotensin II type 1 receptor antagonists potential doping agents?". Sports Medicine. 38 (12): 1065–1079. doi:10.2165/00007256-200838120-00008. PMID 19026021. S2CID 7614657.
Montgomery HE, Clarkson P, Dollery CM, Prasad K, Losi MA, Hemingway H, et al. (August 1997). "Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training". Circulation. 96 (3): 741–747. doi:10.1161/01.CIR.96.3.741. PMID 9264477.
Costa AM, Silva AJ, Garrido ND, Louro H, de Oliveira RJ, Breitenfeld L (August 2009). "Association between ACE D allele and elite short distance swimming". European Journal of Applied Physiology. 106 (6): 785–790. doi:10.1007/s00421-009-1080-z. hdl:10400.15/3565. PMID 19458960. S2CID 21167767.
Skeggs LT, Kahn JR, Shumway NP (March 1956). "The preparation and function of the hypertensin-converting enzyme". The Journal of Experimental Medicine. 103 (3): 295–299. doi:10.1084/jem.103.3.295. PMC 2136590. PMID 13295487.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Hemming ML, Selkoe DJ (November 2005). "Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor". The Journal of Biological Chemistry. 280 (45): 37644–37650. doi:10.1074/jbc.M508460200. PMC 2409196. PMID 16154999.
Qiu WQ, Mwamburi M, Besser LM, Zhu H, Li H, Wallack M, et al. (1 January 2013). "Angiotensin converting enzyme inhibitors and the reduced risk of Alzheimer's disease in the absence of apolipoprotein E4 allele". Journal of Alzheimer's Disease. 37 (2): 421–428. doi:10.3233/JAD-130716. PMC 3972060. PMID 23948883.
Delanghe JR, Speeckaert MM, De Buyzere ML (June 2020). "The host's angiotensin-converting enzyme polymorphism may explain epidemiological findings in COVID-19 infections". Clinica Chimica Acta; International Journal of Clinical Chemistry. 505: 192–193. doi:10.1016/j.cca.2020.03.031. PMC 7102561. PMID 32220422.
Flück M, Kramer M, Fitze DP, Kasper S, Franchi MV, Valdivieso P (8 May 2019). "Cellular Aspects of Muscle Specialization Demonstrate Genotype - Phenotype Interaction Effects in Athletes". Frontiers in Physiology. 10: 526. doi:10.3389/fphys.2019.00526. PMC 6518954. PMID 31139091.
Skeggs LT, Kahn JR, Shumway NP (March 1956). "The preparation and function of the hypertensin-converting enzyme". The Journal of Experimental Medicine. 103 (3): 295–299. doi:10.1084/jem.103.3.295. PMC 2136590. PMID 13295487.

pharmpharm.ru

Natesh R, Schwager SL, Sturrock ED, Acharya KR (January 2003). "Crystal structure of the human angiotensin-converting enzyme-lisinopril complex". Nature. 421 (6922): 551–554. Bibcode:2003Natur.421..551N. doi:10.1038/nature01370. PMID 12540854. S2CID 4137382. Archived from the original on 26 November 2022. Retrieved 22 May 2020.

science20.com

"ACE Enzyme May Enhance Immune Responses And Prevent Alzheimer's". Science 2.0. 27 August 2014. Archived from the original on 7 March 2016. Retrieved 1 March 2016.

semanticscholar.org

api.semanticscholar.org

Wang W, McKinnie SM, Farhan M, Paul M, McDonald T, McLean B, et al. (August 2016). "Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17: Physiological Effects in the Cardiovascular System". Hypertension. 68 (2): 365–377. doi:10.1161/HYPERTENSIONAHA.115.06892. PMID 27217402. S2CID 829514.
Natesh R, Schwager SL, Sturrock ED, Acharya KR (January 2003). "Crystal structure of the human angiotensin-converting enzyme-lisinopril complex". Nature. 421 (6922): 551–554. Bibcode:2003Natur.421..551N. doi:10.1038/nature01370. PMID 12540854. S2CID 4137382. Archived from the original on 26 November 2022. Retrieved 22 May 2020.
Wang P, Fedoruk MN, Rupert JL (2008). "Keeping pace with ACE: are ACE inhibitors and angiotensin II type 1 receptor antagonists potential doping agents?". Sports Medicine. 38 (12): 1065–1079. doi:10.2165/00007256-200838120-00008. PMID 19026021. S2CID 7614657.
Costa AM, Silva AJ, Garrido ND, Louro H, de Oliveira RJ, Breitenfeld L (August 2009). "Association between ACE D allele and elite short distance swimming". European Journal of Applied Physiology. 106 (6): 785–790. doi:10.1007/s00421-009-1080-z. hdl:10400.15/3565. PMID 19458960. S2CID 21167767.

web.archive.org

Natesh R, Schwager SL, Sturrock ED, Acharya KR (January 2003). "Crystal structure of the human angiotensin-converting enzyme-lisinopril complex". Nature. 421 (6922): 551–554. Bibcode:2003Natur.421..551N. doi:10.1038/nature01370. PMID 12540854. S2CID 4137382. Archived from the original on 26 November 2022. Retrieved 22 May 2020.
"Angiotensin converting enzyme (ace) inhibitors" (PDF). British Hypertension Society. Archived from the original (PDF) on 18 November 2017.
Klabunde RE. "ACE-inhibitors". Cardiovascular Pharmacology Concepts. cvpharmacology.com. Archived from the original on 2 February 2009. Retrieved 26 March 2009.
"The Importance of Treating the Blood Pressure: ACE Inhibitors May Slow Alzheimer's Disease". Medscape. Medscape Cardiology. 2004. Archived from the original on 31 August 2016. Retrieved 1 March 2016.
"ACE Enzyme May Enhance Immune Responses And Prevent Alzheimer's". Science 2.0. 27 August 2014. Archived from the original on 7 March 2016. Retrieved 1 March 2016.
Sanders J, Montgomery H, Woods D (2001). "Kardiale Anpassung an Körperliches Training" [The cardiac response to physical training] (PDF). Deutsche Zeitschrift für Sportmednizin (in German). 52 (3): 86–92. Archived (PDF) from the original on 8 March 2016. Retrieved 1 March 2016.

zeitschrift-sportmedizin.de

Sanders J, Montgomery H, Woods D (2001). "Kardiale Anpassung an Körperliches Training" [The cardiac response to physical training] (PDF). Deutsche Zeitschrift für Sportmednizin (in German). 52 (3): 86–92. Archived (PDF) from the original on 8 March 2016. Retrieved 1 March 2016.