Analysis of information sources in references of the Wikipedia article "Araroba powder" in English language version.
Dithranol has been derived from Goa powder extracted from the araroba tree which grew in the Bahia province in Brazil. It was imported from Brazil to India where it was used for centuries to treat ringworm. In 1876, a patient of Balmano Squire who had mistaken his psoriasis to be ringworm told him that he had used the powder to treat his "ringed" psoriasis and had got good results. Later, the active ingredient in the powder was identified as chrysarobin from which the first synthetic preparation, anthralin was derived. Anthralin was found to be an effective treatment for psoriasis by Galewsky in 1916.
Anthralin is available in multiple formulations, including cream, ointment or paste.
Anthralin is a synthetic compound derived from chrysarophanic acid, which is an extract of the Vouacopoua araroba tree. Its mechanism of action has not been worked out, but it is thought to decrease cell turnover. It also exerts strong anti-inflammatory effects by inhibiting neutrophil and monocyte functions. A main advantage of this therapy is its lack of long-term side effects, which allows reintroduction of the medication as often as needed. Anthralin can, however, discolor hair, clothing, and surrounding skin and often causes irritant dermatitis when applied at a concentration that exceeds instructions. For plaque psoriasis, a low concentration of 0.05% to 1% anthralin incorporated into petrolatum or zinc paste can be applied once daily for 30 minutes. The application time can be slowly increased as tolerated.
Dithranol has been derived from Goa powder extracted from the araroba tree which grew in the Bahia province in Brazil. It was imported from Brazil to India where it was used for centuries to treat ringworm. In 1876, a patient of Balmano Squire who had mistaken his psoriasis to be ringworm told him that he had used the powder to treat his "ringed" psoriasis and had got good results. Later, the active ingredient in the powder was identified as chrysarobin from which the first synthetic preparation, anthralin was derived. Anthralin was found to be an effective treatment for psoriasis by Galewsky in 1916.
Dithranol has been derived from Goa powder extracted from the araroba tree which grew in the Bahia province in Brazil. It was imported from Brazil to India where it was used for centuries to treat ringworm. In 1876, a patient of Balmano Squire who had mistaken his psoriasis to be ringworm told him that he had used the powder to treat his "ringed" psoriasis and had got good results. Later, the active ingredient in the powder was identified as chrysarobin from which the first synthetic preparation, anthralin was derived. Anthralin was found to be an effective treatment for psoriasis by Galewsky in 1916.
Anthralin is available in multiple formulations, including cream, ointment or paste.
Anthralin is available in multiple formulations, including cream, ointment or paste.
Dithranol has been derived from Goa powder extracted from the araroba tree which grew in the Bahia province in Brazil. It was imported from Brazil to India where it was used for centuries to treat ringworm. In 1876, a patient of Balmano Squire who had mistaken his psoriasis to be ringworm told him that he had used the powder to treat his "ringed" psoriasis and had got good results. Later, the active ingredient in the powder was identified as chrysarobin from which the first synthetic preparation, anthralin was derived. Anthralin was found to be an effective treatment for psoriasis by Galewsky in 1916.
Anthralin is available in multiple formulations, including cream, ointment or paste.
Anthralin is a synthetic compound derived from chrysarophanic acid, which is an extract of the Vouacopoua araroba tree. Its mechanism of action has not been worked out, but it is thought to decrease cell turnover. It also exerts strong anti-inflammatory effects by inhibiting neutrophil and monocyte functions. A main advantage of this therapy is its lack of long-term side effects, which allows reintroduction of the medication as often as needed. Anthralin can, however, discolor hair, clothing, and surrounding skin and often causes irritant dermatitis when applied at a concentration that exceeds instructions. For plaque psoriasis, a low concentration of 0.05% to 1% anthralin incorporated into petrolatum or zinc paste can be applied once daily for 30 minutes. The application time can be slowly increased as tolerated.