CCR5 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "CCR5" in English language version.

refsWebsite

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98nih.gov

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67doi.org

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9semanticscholar.org

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1clinicaltrials.gov

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hal.archives-ouvertes.fr

Faure E, Royer-Carenzi M (December 2008). "Is the European spatial distribution of the HIV-1-resistant CCR5-Delta32 allele formed by a breakdown of the pathocenosis due to the historical Roman expansion?" (PDF). Infection, Genetics and Evolution. 8 (6): 864–874. doi:10.1016/j.meegid.2008.08.007. PMID 18790087. S2CID 32881202.

clinicaltrials.gov

"Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 for HIV (Zinc-Finger)". U.S. National Institutes of Health. 9 December 2009. Retrieved 30 December 2009.

doi.org

Jiao X, Nawab O, Patel T, Kossenkov AV, Halama N, Jaeger D, et al. (October 2019). "Recent Advances Targeting CCR5 for Cancer and Its Role in Immuno-Oncology". Cancer Research. 79 (19): 4801–4807. doi:10.1158/0008-5472.CAN-19-1167. PMC 6810651. PMID 31292161.
de Silva E, Stumpf MP (December 2004). "HIV and the CCR5-Delta32 resistance allele". FEMS Microbiology Letters. 241 (1): 1–12. doi:10.1016/j.femsle.2004.09.040. PMID 15556703.
Hütter G, Nowak D, Mossner M, Ganepola S, Müssig A, Allers K, et al. (February 2009). "Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation". The New England Journal of Medicine. 360 (7): 692–698. doi:10.1056/NEJMoa0802905. PMID 19213682.
Allers K, Hütter G, Hofmann J, Loddenkemper C, Rieger K, Thiel E, et al. (March 2011). "Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation". Blood. 117 (10): 2791–2799. doi:10.1182/blood-2010-09-309591. PMID 21148083.
Zhen A, Kitchen S (December 2013). "Stem-cell-based gene therapy for HIV infection". Viruses. 6 (1): 1–12. doi:10.3390/v6010001. PMC 3917429. PMID 24368413.
Kay MA, Walker BD (March 2014). "Engineering cellular resistance to HIV". The New England Journal of Medicine. 370 (10): 968–969. doi:10.1056/NEJMe1400593. PMID 24597871.
Tebas P, Stein D, Tang WW, Frank I, Wang SQ, Lee G, et al. (March 2014). "Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV". The New England Journal of Medicine. 370 (10): 901–910. doi:10.1056/NEJMoa1300662. PMC 4084652. PMID 24597865.
Samson M, Labbe O, Mollereau C, Vassart G, Parmentier M (March 1996). "Molecular cloning and functional expression of a new human CC-chemokine receptor gene". Biochemistry. 35 (11): 3362–3367. doi:10.1021/bi952950g. PMID 8639485.
Struyf S, Menten P, Lenaerts JP, Put W, D'Haese A, De Clercq E, et al. (July 2001). "Diverging binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils". European Journal of Immunology. 31 (7): 2170–2178. doi:10.1002/1521-4141(200107)31:7<2170::AID-IMMU2170>3.0.CO;2-D. PMID 11449371.
Miyakawa T, Obaru K, Maeda K, Harada S, Mitsuya H (February 2002). "Identification of amino acid residues critical for LD78beta, a variant of human macrophage inflammatory protein-1alpha, binding to CCR5 and inhibition of R5 human immunodeficiency virus type 1 replication". The Journal of Biological Chemistry. 277 (7): 4649–4655. doi:10.1074/jbc.M109198200. PMID 11734558.
Slimani H, Charnaux N, Mbemba E, Saffar L, Vassy R, Vita C, et al. (October 2003). "Interaction of RANTES with syndecan-1 and syndecan-4 expressed by human primary macrophages". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1617 (1–2): 80–88. doi:10.1016/j.bbamem.2003.09.006. PMID 14637022.
Proudfoot AE, Fritchley S, Borlat F, Shaw JP, Vilbois F, Zwahlen C, et al. (April 2001). "The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity". The Journal of Biological Chemistry. 276 (14): 10620–10626. doi:10.1074/jbc.M010867200. PMID 11116158.
Velasco-Velázquez M, Jiao X, De La Fuente M, Pestell TG, Ertel A, Lisanti MP, et al. (August 2012). "CCR5 antagonist blocks metastasis of basal breast cancer cells". Cancer Research. 72 (15): 3839–3850. doi:10.1158/0008-5472.CAN-11-3917. PMID 22637726.
Sicoli D, Jiao X, Ju X, Velasco-Velazquez M, Ertel A, Addya S, et al. (December 2014). "CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines". Cancer Research. 74 (23): 7103–7114. doi:10.1158/0008-5472.CAN-14-0612. PMC 4294544. PMID 25452256.
Velasco-Velázquez M, Xolalpa W, Pestell RG (November 2014). "The potential to target CCL5/CCR5 in breast cancer". Expert Opinion on Therapeutic Targets. 18 (11): 1265–1275. doi:10.1517/14728222.2014.949238. PMID 25256399. S2CID 7976259.
Jiao X, Velasco-Velázquez MA, Wang M, Li Z, Rui H, Peck AR, et al. (April 2018). "CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion". Cancer Research. 78 (7): 1657–1671. doi:10.1158/0008-5472.CAN-17-0915. PMC 6331183. PMID 29358169.
Barmania F, Pepper MS (December 2013). "C-C chemokine receptor type five (CCR5): An emerging target for the control of HIV infection". Applied & Translational Genomics. 2 (a): 3–16. doi:10.1016/j.atg.2013.05.004. PMC 5133339. PMID 27942440.
Jasinska AJ, Pandrea I, Apetrei C (27 January 2022). "CCR5 as a Coreceptor for Human Immunodeficiency Virus and Simian Immunodeficiency Viruses: A Prototypic Love-Hate Affair". Frontiers in Immunology. 13: 835994. doi:10.3389/fimmu.2022.835994. ISSN 1664-3224. PMC 8829453. PMID 35154162.
Chen Z, Kwon D, Jin Z, Monard S, Telfer P, Jones MS, et al. (December 1998). "Natural infection of a homozygous delta24 CCR5 red-capped mangabey with an R2b-tropic simian immunodeficiency virus". The Journal of Experimental Medicine. 188 (11): 2057–2065. doi:10.1084/jem.188.11.2057. PMC 2212380. PMID 9841919.
Paiardini M, Cervasi B, Reyes-Aviles E, Micci L, Ortiz AM, Chahroudi A, et al. (June 2011). "Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression". Nature Medicine. 17 (7): 830–836. doi:10.1038/nm.2395. PMC 3253129. PMID 21706028.
Ma D, Jasinska AJ, Feyertag F, Wijewardana V, Kristoff J, He T, et al. (May 2014). "Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild". Journal of Virology. 88 (10): 5687–5705. doi:10.1128/JVI.03606-13. PMC 4019088. PMID 24623416.
Pandrea I, Onanga R, Souquiere S, Mouinga-Ondéme A, Bourry O, Makuwa M, et al. (June 2008). "Paucity of CD4+ CCR5+ T cells may prevent transmission of simian immunodeficiency virus in natural nonhuman primate hosts by breast-feeding". Journal of Virology. 82 (11): 5501–5509. doi:10.1128/JVI.02555-07. PMC 2395173. PMID 18385229.
Murphy PM (February 2001). "Viral exploitation and subversion of the immune system through chemokine mimicry". Nature Immunology. 2 (2): 116–122. doi:10.1038/84214. PMID 11175803. S2CID 29364407.
Alkhatib G (March 2009). "The biology of CCR5 and CXCR4". Current Opinion in HIV and AIDS. 4 (2): 96–103. doi:10.1097/COH.0b013e328324bbec. PMC 2718543. PMID 19339947.
Anderson J, Akkina R (September 2007). "Complete knockdown of CCR5 by lentiviral vector-expressed siRNAs and protection of transgenic macrophages against HIV-1 infection". Gene Therapy. 14 (17): 1287–1297. doi:10.1038/sj.gt.3302958. PMID 17597795.
Lieberman-Blum SS, Fung HB, Bandres JC (July 2008). "Maraviroc: a CCR5-receptor antagonist for the treatment of HIV-1 infection". Clinical Therapeutics. 30 (7): 1228–1250. doi:10.1016/s0149-2918(08)80048-3. PMID 18691983.
Nazari R, Joshi S (August 2008). "CCR5 as target for HIV-1 gene therapy". Current Gene Therapy. 8 (4): 264–272. doi:10.2174/156652308785160674. PMID 18691022.
Taylor BM, Foulke JS, Flinko R, Heredia A, DeVico A, Reitz M (June 2008). "An alteration of human immunodeficiency virus gp41 leads to reduced CCR5 dependence and CD4 independence". Journal of Virology. 82 (11): 5460–5471. doi:10.1128/JVI.01049-07. PMC 2395218. PMID 18353949.
Jiao X, Wang M, Zhang Z, Li Z, Ni D, Ashton AW, et al. (January 2021). "Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy". Breast Cancer Research. 23 (1): 11. doi:10.1186/s13058-021-01391-1. PMC 7825185. PMID 33485378.
Frankenberger C, Rabe D, Bainer R, Sankarasharma D, Chada K, Krausz T, et al. (October 2015). "Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages". Cancer Research. 75 (19): 4063–4073. doi:10.1158/0008-5472.CAN-14-3394. PMC 4592465. PMID 26238785.
Halama N, Zoernig I, Berthel A, Kahlert C, Klupp F, Suarez-Carmona M, et al. (April 2016). "Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients". Cancer Cell. 29 (4): 587–601. doi:10.1016/j.ccell.2016.03.005. PMID 27070705.
Joy MT, Ben Assayag E, Shabashov-Stone D, Liraz-Zaltsman S, Mazzitelli J, Arenas M, et al. (February 2019). "CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury". Cell. 176 (5): 1143–1157.e13. doi:10.1016/j.cell.2019.01.044. PMC 7259116. PMID 30794775.
Galvani AP, Slatkin M (December 2003). "Evaluating plague and smallpox as historical selective pressures for the CCR5-Delta 32 HIV-resistance allele". Proceedings of the National Academy of Sciences of the United States of America. 100 (25): 15276–15279. Bibcode:2003PNAS..10015276G. doi:10.1073/pnas.2435085100. PMC 299980. PMID 14645720.
Stephens JC, Reich DE, Goldstein DB, Shin HD, Smith MW, Carrington M, et al. (June 1998). "Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes". American Journal of Human Genetics. 62 (6): 1507–1515. doi:10.1086/301867. PMC 1377146. PMID 9585595.
Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, Allikmets R, et al. (September 1996). "Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study". Science. 273 (5283): 1856–1862. Bibcode:1996Sci...273.1856D. doi:10.1126/science.273.5283.1856. PMID 8791590. S2CID 21160580.
Samson M, Libert F, Doranz BJ, Rucker J, Liesnard C, Farber CM, et al. (August 1996). "Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene". Nature. 382 (6593): 722–725. Bibcode:1996Natur.382..722S. doi:10.1038/382722a0. PMID 8751444. S2CID 4370818.
Liu R, Paxton WA, Choe S, Ceradini D, Martin SR, Horuk R, et al. (August 1996). "Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection". Cell. 86 (3): 367–377. doi:10.1016/s0092-8674(00)80110-5. PMID 8756719. S2CID 16965624.
Benkirane M, Jin DY, Chun RF, Koup RA, Jeang KT (December 1997). "Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5delta32". The Journal of Biological Chemistry. 272 (49): 30603–30606. doi:10.1074/jbc.272.49.30603. PMID 9388191.
Michael NL, Louie LG, Rohrbaugh AL, Schultz KA, Dayhoff DE, Wang CE, et al. (October 1997). "The role of CCR5 and CCR2 polymorphisms in HIV-1 transmission and disease progression". Nature Medicine. 3 (10): 1160–1162. doi:10.1038/nm1097-1160. PMID 9334732. S2CID 23196048.
Laurichesse JJ, Persoz A, Theodorou I, Rouzioux C, Delfraissy JF, Meyer L (May 2007). "Improved virological response to highly active antiretroviral therapy in HIV-1-infected patients carrying the CCR5 Delta32 deletion". HIV Medicine. 8 (4): 213–219. doi:10.1111/j.1468-1293.2007.00455.x. PMID 17461848. S2CID 24900064.
Zhou M, Greenhill S, Huang S, Silva TK, Sano Y, Wu S, et al. (December 2016). "CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory". eLife. 5. doi:10.7554/eLife.20985. PMC 5213777. PMID 27996938.
Galvani AP, Novembre J (February 2005). "The evolutionary history of the CCR5-Delta32 HIV-resistance mutation". Microbes and Infection. 7 (2): 302–309. doi:10.1016/j.micinf.2004.12.006. PMID 15715976.
Libert F, Cochaux P, Beckman G, Samson M, Aksenova M, Cao A, et al. (March 1998). "The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe". Human Molecular Genetics. 7 (3): 399–406. doi:10.1093/hmg/7.3.399. PMID 9466996.
Lucotte G (September 2001). "Distribution of the CCR5 gene 32-basepair deletion in West Europe. A hypothesis about the possible dispersion of the mutation by the Vikings in historical times". Human Immunology. 62 (9): 933–936. doi:10.1016/S0198-8859(01)00292-0. PMID 11543895.
Keele BF, Van Heuverswyn F, Li Y, Bailes E, Takehisa J, Santiago ML, et al. (July 2006). "Chimpanzee reservoirs of pandemic and nonpandemic HIV-1". Science. 313 (5786): 523–526. Bibcode:2006Sci...313..523K. doi:10.1126/science.1126531. PMC 2442710. PMID 16728595.
Hahn BH, Shaw GM, De Cock KM, Sharp PM (January 2000). "AIDS as a zoonosis: scientific and public health implications". Science. 287 (5453): 607–614. Bibcode:2000Sci...287..607H. doi:10.1126/science.287.5453.607. PMID 10649986.
Faure E, Royer-Carenzi M (December 2008). "Is the European spatial distribution of the HIV-1-resistant CCR5-Delta32 allele formed by a breakdown of the pathocenosis due to the historical Roman expansion?" (PDF). Infection, Genetics and Evolution. 8 (6): 864–874. doi:10.1016/j.meegid.2008.08.007. PMID 18790087. S2CID 32881202.
Dawson TC, Beck MA, Kuziel WA, Henderson F, Maeda N (June 2000). "Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus". The American Journal of Pathology. 156 (6): 1951–1959. doi:10.1016/S0002-9440(10)65068-7. PMC 1850091. PMID 10854218.
Vargas AE, Cechim G, Correa JF, Gomes PA, Macedo GS, de Medeiros RM, et al. (July 2009). "Pros and cons of a missing chemokine receptor--comments on "Is the European spatial distribution of the HIV-1-resistant CCR5-D32 allele formed by a breakdown of the pathocenosis due to the historical Roman expansion?" by Eric Faure and Manuela Royer-Carenzi (2008)". Infection, Genetics and Evolution. 9 (4): 387–389. doi:10.1016/j.meegid.2009.01.001. PMID 19472441.
O'Brien SJ, Dean M (September 1997). "In search of AIDS-resistance genes". Scientific American. 277 (3): 44–51. Bibcode:1997SciAm.277c..44O. doi:10.1038/scientificamerican0997-44. PMID 9274039.
McEvedy C (February 1988). "The bubonic plague". Scientific American. 258 (2): 118–123. Bibcode:1988SciAm.258b.118M. doi:10.1038/scientificamerican0288-118. PMID 3055286.
Keeling MJ, Gilligan CA (November 2000). "Bubonic plague: a metapopulation model of a zoonosis". Proceedings. Biological Sciences. 267 (1458): 2219–2230. doi:10.1098/rspb.2000.1272. PMC 1690796. PMID 11413636.
Appleby AB (1980). "The disappearance of plague: a continuing puzzle". The Economic History Review. 33 (2): 161–173. doi:10.2307/2595837. JSTOR 2595837. PMID 11614424.
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Novembre J, Galvani AP, Slatkin M (November 2005). "The geographic spread of the CCR5 Delta32 HIV-resistance allele". PLOS Biology. 3 (11): e339. doi:10.1371/journal.pbio.0030339. PMC 1255740. PMID 16216086.
OBrien SJ (March 2024). "Legacy of a magic gene-CCR5-∆32: From discovery to clinical benefit in a generation". Proceedings of the National Academy of Sciences of the United States of America. 121 (12): e2321907121. doi:10.1073/pnas.2321907121. PMC 10962972. PMID 38457490.
Klein RS (January 2008). "A moving target: the multiple roles of CCR5 in infectious diseases". The Journal of Infectious Diseases. 197 (2): 183–186. doi:10.1086/524692. PMID 18179384.
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Glass WG, Lim JK, Cholera R, Pletnev AG, Gao JL, Murphy PM (October 2005). "Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection". The Journal of Experimental Medicine. 202 (8): 1087–1098. doi:10.1084/jem.20042530. PMC 2213214. PMID 16230476.
Steinberger P, Andris-Widhopf J, Bühler B, Torbett BE, Barbas CF (January 2000). "Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion". Proceedings of the National Academy of Sciences of the United States of America. 97 (2): 805–810. Bibcode:2000PNAS...97..805S. doi:10.1073/pnas.97.2.805. PMC 15412. PMID 10639161.
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ensembl.org

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GRCh38: Ensembl release 89: ENSG00000160791 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000079227 – Ensembl, May 2017

harvard.edu

ui.adsabs.harvard.edu

Galvani AP, Slatkin M (December 2003). "Evaluating plague and smallpox as historical selective pressures for the CCR5-Delta 32 HIV-resistance allele". Proceedings of the National Academy of Sciences of the United States of America. 100 (25): 15276–15279. Bibcode:2003PNAS..10015276G. doi:10.1073/pnas.2435085100. PMC 299980. PMID 14645720.
Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, Allikmets R, et al. (September 1996). "Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study". Science. 273 (5283): 1856–1862. Bibcode:1996Sci...273.1856D. doi:10.1126/science.273.5283.1856. PMID 8791590. S2CID 21160580.
Samson M, Libert F, Doranz BJ, Rucker J, Liesnard C, Farber CM, et al. (August 1996). "Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene". Nature. 382 (6593): 722–725. Bibcode:1996Natur.382..722S. doi:10.1038/382722a0. PMID 8751444. S2CID 4370818.
Keele BF, Van Heuverswyn F, Li Y, Bailes E, Takehisa J, Santiago ML, et al. (July 2006). "Chimpanzee reservoirs of pandemic and nonpandemic HIV-1". Science. 313 (5786): 523–526. Bibcode:2006Sci...313..523K. doi:10.1126/science.1126531. PMC 2442710. PMID 16728595.
Hahn BH, Shaw GM, De Cock KM, Sharp PM (January 2000). "AIDS as a zoonosis: scientific and public health implications". Science. 287 (5453): 607–614. Bibcode:2000Sci...287..607H. doi:10.1126/science.287.5453.607. PMID 10649986.
O'Brien SJ, Dean M (September 1997). "In search of AIDS-resistance genes". Scientific American. 277 (3): 44–51. Bibcode:1997SciAm.277c..44O. doi:10.1038/scientificamerican0997-44. PMID 9274039.
McEvedy C (February 1988). "The bubonic plague". Scientific American. 258 (2): 118–123. Bibcode:1988SciAm.258b.118M. doi:10.1038/scientificamerican0288-118. PMID 3055286.
Steinberger P, Andris-Widhopf J, Bühler B, Torbett BE, Barbas CF (January 2000). "Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion". Proceedings of the National Academy of Sciences of the United States of America. 97 (2): 805–810. Bibcode:2000PNAS...97..805S. doi:10.1073/pnas.97.2.805. PMC 15412. PMID 10639161.

ocp.hul.harvard.edu

"The Great Plague of London, 1665". Contagion, Historical Views of Diseases and Epidemics. Harvard University. Retrieved 2 March 2015.

jstor.org

Appleby AB (1980). "The disappearance of plague: a continuing puzzle". The Economic History Review. 33 (2): 161–173. doi:10.2307/2595837. JSTOR 2595837. PMID 11614424.

nationalgeographic.com

news.nationalgeographic.com

"DNA in London Grave May Help Solve Mysteries of the Great Plague". 8 September 2016. Archived from the original on 9 September 2016. Retrieved 18 September 2016.

nih.gov

pubmed.ncbi.nlm.nih.gov

Jiao X, Nawab O, Patel T, Kossenkov AV, Halama N, Jaeger D, et al. (October 2019). "Recent Advances Targeting CCR5 for Cancer and Its Role in Immuno-Oncology". Cancer Research. 79 (19): 4801–4807. doi:10.1158/0008-5472.CAN-19-1167. PMC 6810651. PMID 31292161.
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"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
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