CRELD2 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "CRELD2" in English language version.

Last modified: 07:55:28, 23 September 2026 (UTC)

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4638nih.gov

5^th place

3023doi.org

2^nd place

106scixplorer.org

low place

62ensembl.org

630^th place

326^th place

11hdl.handle.net

66^th place

34^th place

doi.org (Global: 2^nd place; English: 2^nd place)

Rupp PA, Fouad GT, Egelston CA, Reifsteck CA, Olson SB, Knosp WM, et al. (July 2002). "Identification, genomic organization and mRNA expression of CRELD1, the founding member of a unique family of matricellular proteins". Gene. 293 (1–2): 47–57. doi:10.1016/S0378-1119(02)00696-0. PMID 12137942.
Oh-hashi K, Koga H, Ikeda S, Shimada K, Hirata Y, Kiuchi K (September 2009). "CRELD2 is a novel endoplasmic reticulum stress-inducible gene". Biochemical and Biophysical Research Communications. 387 (3): 504–510. Bibcode:2009BBRC..387..504O. doi:10.1016/j.bbrc.2009.07.047. PMID 19615339.
Oh-hashi K, Kunieda R, Hirata Y, Kiuchi K (August 2011). "Biosynthesis and secretion of mouse cysteine-rich with EGF-like domains 2". FEBS Letters. 585 (15): 2481–2487. Bibcode:2011FEBSL.585.2481O. doi:10.1016/j.febslet.2011.06.029. PMID 21729698.
Ren J, Bi Y, Sowers JR, Hetz C, Zhang Y (July 2021). "Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases". Nature Reviews. Cardiology. 18 (7): 499–521. doi:10.1038/s41569-021-00511-w. PMID 33619348.
Kim Y, Park SJ, Manson SR, Molina CA, Kidd K, Thiessen-Philbrook H, et al. (December 2017). "Elevated urinary CRELD2 is associated with endoplasmic reticulum stress-mediated kidney disease". JCI Insight. 2 (23) e92896. doi:10.1172/jci.insight.92896. PMC 5752286. PMID 29212948.
Maslen CL, Babcock D, Redig JK, Kapeli K, Akkari YM, Olson SB (November 2006). "CRELD2: gene mapping, alternate splicing, and comparative genomic identification of the promoter region". Gene. 382: 111–120. doi:10.1016/j.gene.2006.06.016. PMID 16919896.
Munro S, Pelham HR (March 1987). "A C-terminal signal prevents secretion of luminal ER proteins". Cell. 48 (5): 899–907. Bibcode:1987Cell...48..899M. doi:10.1016/0092-8674(87)90086-9. PMID 3545499.
Newstead S, Barr F (October 2020). "Molecular basis for KDEL-mediated retrieval of escaped ER-resident proteins - SWEET talking the COPs". Journal of Cell Science. 133 (19) jcs250100. doi:10.1242/jcs.250100. PMC 7561476. PMID 33037041.
Oh-Hashi K, Fujimura K, Norisada J, Hirata Y (August 2018). "Expression analysis and functional characterization of the mouse cysteine-rich with EGF-like domains 2". Scientific Reports. 8 (1) 12236. Bibcode:2018NatSR...812236O. doi:10.1038/s41598-018-30362-4. PMC 6093884. PMID 30111858.
Kern P, Balzer NR, Blank N, Cygon C, Wunderling K, Bender F, et al. (October 2021). "Creld2 function during unfolded protein response is essential for liver metabolism homeostasis". FASEB Journal. 35 (10) e21939. doi:10.1096/fj.202002713RR. PMC 12316087. PMID 34549824.
Tang Q, Liu Q, Li Y, Mo L, He J (2023). "CRELD2, endoplasmic reticulum stress, and human diseases". Frontiers in Endocrinology. 14 1117414. Lausanne. doi:10.3389/fendo.2023.1117414. PMC 10018036. PMID 36936176.
Takemoto H, Yoshimori T, Yamamoto A, Miyata Y, Yahara I, Inoue K, et al. (July 1992). "Heavy chain binding protein (BiP/GRP78) and endoplasmin are exported from the endoplasmic reticulum in rat exocrine pancreatic cells, similar to protein disulfide-isomerase". Archives of Biochemistry and Biophysics. 296 (1): 129–136. doi:10.1016/0003-9861(92)90554-a. PMID 1318687.
Liu CL, Zhong W, He YY, Li X, Li S, He KL (February 2016). "Genome-wide analysis of tunicamycin-induced endoplasmic reticulum stress response and the protective effect of endoplasmic reticulum inhibitors in neonatal rat cardiomyocytes". Molecular and Cellular Biochemistry. 413 (1–2): 57–67. doi:10.1007/s11010-015-2639-0. PMID 26738490.
Navas-Madroñal M, Rodriguez C, Kassan M, Fité J, Escudero JR, Cañes L, et al. (July 2019). "Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm". Clinical Science. 133 (13). London: 1421–1438. doi:10.1042/CS20190399. hdl:10261/201516. PMID 31239294.
Hartley CL, Edwards S, Mullan L, Bell PA, Fresquet M, Boot-Handford RP, et al. (December 2013). "Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases". Human Molecular Genetics. 22 (25): 5262–5275. doi:10.1093/hmg/ddt383. PMC 3842181. PMID 23956175.
Hughes A, Oxford AE, Tawara K, Jorcyk CL, Oxford JT (March 2017). "Endoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology; Contributing Factors to Apoptosis and Osteoarthritis". International Journal of Molecular Sciences. 18 (3): 665. doi:10.3390/ijms18030665. PMC 5372677. PMID 28335520.
Guo J, Ren R, Sun K, He J, Shao J (April 2021). "PERK signaling pathway in bone metabolism: Friend or foe?". Cell Proliferation. 54 (4) e13011. doi:10.1111/cpr.13011. PMC 8016635. PMID 33615575.
Rellmann Y, Eidhof E, Dreier R (February 2021). "Review: ER stress-induced cell death in osteoarthritic cartilage". Cellular Signalling. 78 109880. doi:10.1016/j.cellsig.2020.109880. PMID 33307190.
Zhang J, Weng Y, Liu X, Wang J, Zhang W, Kim SH, et al. (2013). "Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells". PLOS ONE. 8 (9) e73086. Bibcode:2013PLoSO...873086Z. doi:10.1371/journal.pone.0073086. PMC 3760886. PMID 24019898.
Duxfield A, Munkley J, Briggs MD, Dennis EP (August 2022). "CRELD2 is a novel modulator of calcium release and calcineurin-NFAT signalling during osteoclast differentiation". Scientific Reports. 12 (1) 13884. Bibcode:2022NatSR..1213884D. doi:10.1038/s41598-022-17347-0. PMC 9381524. PMID 35974042.
Boyle ST, Poltavets V, Kular J, Pyne NT, Sandow JJ, Lewis AC, et al. (July 2020). "ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism". Nature Cell Biology. 22 (7): 882–895. doi:10.1038/s41556-020-0523-y. PMID 32451439.
Salvagno C, Mandula JK, Rodriguez PC, Cubillos-Ruiz JR (November 2022). "Decoding endoplasmic reticulum stress signals in cancer cells and antitumor immunity". Trends in Cancer. 8 (11): 930–943. doi:10.1016/j.trecan.2022.06.006. PMC 9588488. PMID 35817701.
Chen MF, Chang CH, Yang LY, Hsieh PH, Shih HN, Ueng SW, et al. (April 2019). "Synovial fluid interleukin-16, interleukin-18, and CRELD2 as novel biomarkers of prosthetic joint infections". Bone & Joint Research. 8 (4): 179–188. doi:10.1302/2046-3758.84.BJR-2018-0291.R1. PMC 6498892. PMID 31069072.

ensembl.org (Global: 630^th place; English: 326^th place)

may2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000184164 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000023272 – Ensembl, May 2017

hdl.handle.net (Global: 66^th place; English: 34^th place)

Navas-Madroñal M, Rodriguez C, Kassan M, Fité J, Escudero JR, Cañes L, et al. (July 2019). "Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm". Clinical Science. 133 (13). London: 1421–1438. doi:10.1042/CS20190399. hdl:10261/201516. PMID 31239294.

nih.gov (Global: 5^th place; English: 5^th place)

pubmed.ncbi.nlm.nih.gov

Rupp PA, Fouad GT, Egelston CA, Reifsteck CA, Olson SB, Knosp WM, et al. (July 2002). "Identification, genomic organization and mRNA expression of CRELD1, the founding member of a unique family of matricellular proteins". Gene. 293 (1–2): 47–57. doi:10.1016/S0378-1119(02)00696-0. PMID 12137942.
Oh-hashi K, Koga H, Ikeda S, Shimada K, Hirata Y, Kiuchi K (September 2009). "CRELD2 is a novel endoplasmic reticulum stress-inducible gene". Biochemical and Biophysical Research Communications. 387 (3): 504–510. Bibcode:2009BBRC..387..504O. doi:10.1016/j.bbrc.2009.07.047. PMID 19615339.
Oh-hashi K, Kunieda R, Hirata Y, Kiuchi K (August 2011). "Biosynthesis and secretion of mouse cysteine-rich with EGF-like domains 2". FEBS Letters. 585 (15): 2481–2487. Bibcode:2011FEBSL.585.2481O. doi:10.1016/j.febslet.2011.06.029. PMID 21729698.
Ren J, Bi Y, Sowers JR, Hetz C, Zhang Y (July 2021). "Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases". Nature Reviews. Cardiology. 18 (7): 499–521. doi:10.1038/s41569-021-00511-w. PMID 33619348.
Kim Y, Park SJ, Manson SR, Molina CA, Kidd K, Thiessen-Philbrook H, et al. (December 2017). "Elevated urinary CRELD2 is associated with endoplasmic reticulum stress-mediated kidney disease". JCI Insight. 2 (23) e92896. doi:10.1172/jci.insight.92896. PMC 5752286. PMID 29212948.
Maslen CL, Babcock D, Redig JK, Kapeli K, Akkari YM, Olson SB (November 2006). "CRELD2: gene mapping, alternate splicing, and comparative genomic identification of the promoter region". Gene. 382: 111–120. doi:10.1016/j.gene.2006.06.016. PMID 16919896.
Munro S, Pelham HR (March 1987). "A C-terminal signal prevents secretion of luminal ER proteins". Cell. 48 (5): 899–907. Bibcode:1987Cell...48..899M. doi:10.1016/0092-8674(87)90086-9. PMID 3545499.
Newstead S, Barr F (October 2020). "Molecular basis for KDEL-mediated retrieval of escaped ER-resident proteins - SWEET talking the COPs". Journal of Cell Science. 133 (19) jcs250100. doi:10.1242/jcs.250100. PMC 7561476. PMID 33037041.
Oh-Hashi K, Fujimura K, Norisada J, Hirata Y (August 2018). "Expression analysis and functional characterization of the mouse cysteine-rich with EGF-like domains 2". Scientific Reports. 8 (1) 12236. Bibcode:2018NatSR...812236O. doi:10.1038/s41598-018-30362-4. PMC 6093884. PMID 30111858.
Kern P, Balzer NR, Blank N, Cygon C, Wunderling K, Bender F, et al. (October 2021). "Creld2 function during unfolded protein response is essential for liver metabolism homeostasis". FASEB Journal. 35 (10) e21939. doi:10.1096/fj.202002713RR. PMC 12316087. PMID 34549824.
Tang Q, Liu Q, Li Y, Mo L, He J (2023). "CRELD2, endoplasmic reticulum stress, and human diseases". Frontiers in Endocrinology. 14 1117414. Lausanne. doi:10.3389/fendo.2023.1117414. PMC 10018036. PMID 36936176.
Takemoto H, Yoshimori T, Yamamoto A, Miyata Y, Yahara I, Inoue K, et al. (July 1992). "Heavy chain binding protein (BiP/GRP78) and endoplasmin are exported from the endoplasmic reticulum in rat exocrine pancreatic cells, similar to protein disulfide-isomerase". Archives of Biochemistry and Biophysics. 296 (1): 129–136. doi:10.1016/0003-9861(92)90554-a. PMID 1318687.
Liu CL, Zhong W, He YY, Li X, Li S, He KL (February 2016). "Genome-wide analysis of tunicamycin-induced endoplasmic reticulum stress response and the protective effect of endoplasmic reticulum inhibitors in neonatal rat cardiomyocytes". Molecular and Cellular Biochemistry. 413 (1–2): 57–67. doi:10.1007/s11010-015-2639-0. PMID 26738490.
Navas-Madroñal M, Rodriguez C, Kassan M, Fité J, Escudero JR, Cañes L, et al. (July 2019). "Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm". Clinical Science. 133 (13). London: 1421–1438. doi:10.1042/CS20190399. hdl:10261/201516. PMID 31239294.
Hartley CL, Edwards S, Mullan L, Bell PA, Fresquet M, Boot-Handford RP, et al. (December 2013). "Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases". Human Molecular Genetics. 22 (25): 5262–5275. doi:10.1093/hmg/ddt383. PMC 3842181. PMID 23956175.
Hughes A, Oxford AE, Tawara K, Jorcyk CL, Oxford JT (March 2017). "Endoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology; Contributing Factors to Apoptosis and Osteoarthritis". International Journal of Molecular Sciences. 18 (3): 665. doi:10.3390/ijms18030665. PMC 5372677. PMID 28335520.
Guo J, Ren R, Sun K, He J, Shao J (April 2021). "PERK signaling pathway in bone metabolism: Friend or foe?". Cell Proliferation. 54 (4) e13011. doi:10.1111/cpr.13011. PMC 8016635. PMID 33615575.
Rellmann Y, Eidhof E, Dreier R (February 2021). "Review: ER stress-induced cell death in osteoarthritic cartilage". Cellular Signalling. 78 109880. doi:10.1016/j.cellsig.2020.109880. PMID 33307190.
Zhang J, Weng Y, Liu X, Wang J, Zhang W, Kim SH, et al. (2013). "Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells". PLOS ONE. 8 (9) e73086. Bibcode:2013PLoSO...873086Z. doi:10.1371/journal.pone.0073086. PMC 3760886. PMID 24019898.
Duxfield A, Munkley J, Briggs MD, Dennis EP (August 2022). "CRELD2 is a novel modulator of calcium release and calcineurin-NFAT signalling during osteoclast differentiation". Scientific Reports. 12 (1) 13884. Bibcode:2022NatSR..1213884D. doi:10.1038/s41598-022-17347-0. PMC 9381524. PMID 35974042.
Boyle ST, Poltavets V, Kular J, Pyne NT, Sandow JJ, Lewis AC, et al. (July 2020). "ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism". Nature Cell Biology. 22 (7): 882–895. doi:10.1038/s41556-020-0523-y. PMID 32451439.
Salvagno C, Mandula JK, Rodriguez PC, Cubillos-Ruiz JR (November 2022). "Decoding endoplasmic reticulum stress signals in cancer cells and antitumor immunity". Trends in Cancer. 8 (11): 930–943. doi:10.1016/j.trecan.2022.06.006. PMC 9588488. PMID 35817701.
Chen MF, Chang CH, Yang LY, Hsieh PH, Shih HN, Ueng SW, et al. (April 2019). "Synovial fluid interleukin-16, interleukin-18, and CRELD2 as novel biomarkers of prosthetic joint infections". Bone & Joint Research. 8 (4): 179–188. doi:10.1302/2046-3758.84.BJR-2018-0291.R1. PMC 6498892. PMID 31069072.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: CRELD2 cysteine-rich with EGF-like domains 2".
Kim Y, Park SJ, Manson SR, Molina CA, Kidd K, Thiessen-Philbrook H, et al. (December 2017). "Elevated urinary CRELD2 is associated with endoplasmic reticulum stress-mediated kidney disease". JCI Insight. 2 (23) e92896. doi:10.1172/jci.insight.92896. PMC 5752286. PMID 29212948.
Newstead S, Barr F (October 2020). "Molecular basis for KDEL-mediated retrieval of escaped ER-resident proteins - SWEET talking the COPs". Journal of Cell Science. 133 (19) jcs250100. doi:10.1242/jcs.250100. PMC 7561476. PMID 33037041.
Oh-Hashi K, Fujimura K, Norisada J, Hirata Y (August 2018). "Expression analysis and functional characterization of the mouse cysteine-rich with EGF-like domains 2". Scientific Reports. 8 (1) 12236. Bibcode:2018NatSR...812236O. doi:10.1038/s41598-018-30362-4. PMC 6093884. PMID 30111858.
Kern P, Balzer NR, Blank N, Cygon C, Wunderling K, Bender F, et al. (October 2021). "Creld2 function during unfolded protein response is essential for liver metabolism homeostasis". FASEB Journal. 35 (10) e21939. doi:10.1096/fj.202002713RR. PMC 12316087. PMID 34549824.
Tang Q, Liu Q, Li Y, Mo L, He J (2023). "CRELD2, endoplasmic reticulum stress, and human diseases". Frontiers in Endocrinology. 14 1117414. Lausanne. doi:10.3389/fendo.2023.1117414. PMC 10018036. PMID 36936176.
Hartley CL, Edwards S, Mullan L, Bell PA, Fresquet M, Boot-Handford RP, et al. (December 2013). "Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases". Human Molecular Genetics. 22 (25): 5262–5275. doi:10.1093/hmg/ddt383. PMC 3842181. PMID 23956175.
Hughes A, Oxford AE, Tawara K, Jorcyk CL, Oxford JT (March 2017). "Endoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology; Contributing Factors to Apoptosis and Osteoarthritis". International Journal of Molecular Sciences. 18 (3): 665. doi:10.3390/ijms18030665. PMC 5372677. PMID 28335520.
Guo J, Ren R, Sun K, He J, Shao J (April 2021). "PERK signaling pathway in bone metabolism: Friend or foe?". Cell Proliferation. 54 (4) e13011. doi:10.1111/cpr.13011. PMC 8016635. PMID 33615575.
Zhang J, Weng Y, Liu X, Wang J, Zhang W, Kim SH, et al. (2013). "Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells". PLOS ONE. 8 (9) e73086. Bibcode:2013PLoSO...873086Z. doi:10.1371/journal.pone.0073086. PMC 3760886. PMID 24019898.
Duxfield A, Munkley J, Briggs MD, Dennis EP (August 2022). "CRELD2 is a novel modulator of calcium release and calcineurin-NFAT signalling during osteoclast differentiation". Scientific Reports. 12 (1) 13884. Bibcode:2022NatSR..1213884D. doi:10.1038/s41598-022-17347-0. PMC 9381524. PMID 35974042.
Salvagno C, Mandula JK, Rodriguez PC, Cubillos-Ruiz JR (November 2022). "Decoding endoplasmic reticulum stress signals in cancer cells and antitumor immunity". Trends in Cancer. 8 (11): 930–943. doi:10.1016/j.trecan.2022.06.006. PMC 9588488. PMID 35817701.
Chen MF, Chang CH, Yang LY, Hsieh PH, Shih HN, Ueng SW, et al. (April 2019). "Synovial fluid interleukin-16, interleukin-18, and CRELD2 as novel biomarkers of prosthetic joint infections". Bone & Joint Research. 8 (4): 179–188. doi:10.1302/2046-3758.84.BJR-2018-0291.R1. PMC 6498892. PMID 31069072.

scixplorer.org (Global: low place; English: low place)

Oh-hashi K, Koga H, Ikeda S, Shimada K, Hirata Y, Kiuchi K (September 2009). "CRELD2 is a novel endoplasmic reticulum stress-inducible gene". Biochemical and Biophysical Research Communications. 387 (3): 504–510. Bibcode:2009BBRC..387..504O. doi:10.1016/j.bbrc.2009.07.047. PMID 19615339.
Oh-hashi K, Kunieda R, Hirata Y, Kiuchi K (August 2011). "Biosynthesis and secretion of mouse cysteine-rich with EGF-like domains 2". FEBS Letters. 585 (15): 2481–2487. Bibcode:2011FEBSL.585.2481O. doi:10.1016/j.febslet.2011.06.029. PMID 21729698.
Munro S, Pelham HR (March 1987). "A C-terminal signal prevents secretion of luminal ER proteins". Cell. 48 (5): 899–907. Bibcode:1987Cell...48..899M. doi:10.1016/0092-8674(87)90086-9. PMID 3545499.
Oh-Hashi K, Fujimura K, Norisada J, Hirata Y (August 2018). "Expression analysis and functional characterization of the mouse cysteine-rich with EGF-like domains 2". Scientific Reports. 8 (1) 12236. Bibcode:2018NatSR...812236O. doi:10.1038/s41598-018-30362-4. PMC 6093884. PMID 30111858.
Zhang J, Weng Y, Liu X, Wang J, Zhang W, Kim SH, et al. (2013). "Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells". PLOS ONE. 8 (9) e73086. Bibcode:2013PLoSO...873086Z. doi:10.1371/journal.pone.0073086. PMC 3760886. PMID 24019898.
Duxfield A, Munkley J, Briggs MD, Dennis EP (August 2022). "CRELD2 is a novel modulator of calcium release and calcineurin-NFAT signalling during osteoclast differentiation". Scientific Reports. 12 (1) 13884. Bibcode:2022NatSR..1213884D. doi:10.1038/s41598-022-17347-0. PMC 9381524. PMID 35974042.

CRELD2 (English Wikipedia)

doi.org (Global: 2nd place; English: 2nd place)

ensembl.org (Global: 630th place; English: 326th place)