Analysis of information sources in references of the Wikipedia article "Coal tar" in English language version.
composition of coal tar will be influenced by the process used for pyrolytic distillation as well as by the original composition of the coal ... He then demonstrated excess cancers occurring in laboratory animals when coal tar is applied to the ears and skin ... [therapeutic effect] is thought to involve decreased epidermal proliferation ... Coal tar is classified as a human carcinogen ... Both inhalation and dermal routes of exposure are considered hazardous.
9.5.1 Coal tar chemicals: Coal tar is a black or dark brown liquid or a high-viscosity semi-solid that is one of the by-products formed when coal is carbonized. Coal tars are complex and variable mixtures of polycyclic aromatic hydrocarbons (PAHs), phenols, and heterocyclic compounds. Because of its flammable composition, coal tar is often used for fire boilers in order to create heat. They must be heated before any heavy oil flows easily.
...are classified as carcinogens of category 1B in accordance with Annex VI to Regulation (EC) No 1272/2008 of the European Parliament
it was concluded that there is sufficient evidence in humans for the carcinogenicity of occupational exposures during paving and roofing with coal tar pitch. ... Six coal-tar pitches and three extracts of coal-tar pitches all produced skin tumours, including carcinomas, when applied to the skin of mice
Evidence for carcinogenicity to humans (sufficient)
it was concluded that there is sufficient evidence in humans for the carcinogenicity of occupational exposures during paving and roofing with coal tar pitch. ... Six coal-tar pitches and three extracts of coal-tar pitches all produced skin tumours, including carcinomas, when applied to the skin of mice
...are classified as carcinogens of category 1B in accordance with Annex VI to Regulation (EC) No 1272/2008 of the European Parliament
keratolytic agent that inhibits excessive proliferation of epidermal cells by reducing DNA synthesis and mitotic activity to normal levels
Evidence for carcinogenicity to humans (sufficient)
keratolytic agent that inhibits excessive proliferation of epidermal cells by reducing DNA synthesis and mitotic activity to normal levels