DNA vaccine (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "DNA vaccine" in English language version.

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Lewis PJ, Babiuk LA (1999). DNA vaccines: a review. Vol. 54. Academic Press. pp. 129–88. doi:10.1016/S0065-3527(08)60367-X. ISBN 978-0-12-039854-6. PMID 10547676. {{cite book}}: |journal= ignored (help)

buffalo.edu

Nealon, Cory (25 November 2014). "A hybrid vehicle that delivers DNA". The State University of New York at Buffalo. Retrieved 16 December 2014.

doi.org

Liu S, Wang S, Lu S (April 2016). "DNA immunization as a technology platform for monoclonal antibody induction". Emerging Microbes & Infections. 5 (4): e33. doi:10.1038/emi.2016.27. PMC 4855071. PMID 27048742.
Khan KH (March 2013). "DNA vaccines: roles against diseases". Germs. 3 (1): 26–35. doi:10.11599/germs.2013.1034. PMC 3882840. PMID 24432284.
Alarcon JB, Waine GW, McManus DP (1999). "DNA Vaccines: Technology and Application as Anti-parasite and Anti-microbial Agents". Advances in Parasitology Volume 42. Vol. 42. pp. 343–410. doi:10.1016/S0065-308X(08)60152-9. ISBN 9780120317424. PMID 10050276.
Robinson HL, Pertmer TM (2000). DNA vaccines for viral infections: basic studies and applications. Advances in Virus Research. Vol. 55. pp. 1–74. doi:10.1016/S0065-3527(00)55001-5. ISBN 9780120398553. PMID 11050940.
White LO, Gibb E, Newham HC, Richardson MD, Warren RC (July 1979). "Comparison of the growth of virulent and attenuated strains of Candida albicans in the kidneys of normal and cortison-treated mice by chitin assay". Mycopathologia. 67 (3): 173–177. doi:10.1007/bf00470753. PMID 384256. S2CID 31914107.
Paoletti E, Lipinskas BR, Samsonoff C, Mercer S, Panicali D (January 1984). "Construction of live vaccines using genetically engineered poxviruses: biological activity of vaccinia virus recombinants expressing the hepatitis B virus surface antigen and the herpes simplex virus glycoprotein D". Proceedings of the National Academy of Sciences of the United States of America. 81 (1): 193–197. Bibcode:1984PNAS...81..193P. doi:10.1073/pnas.81.1.193. PMC 344637. PMID 6320164.
Ulmer JB, Donnelly JJ, Parker SE, Rhodes GH, Felgner PL, Dwarki VJ, et al. (March 1993). "Heterologous protection against influenza by injection of DNA encoding a viral protein". Science. 259 (5102): 1745–1749. Bibcode:1993Sci...259.1745U. doi:10.1126/science.8456302. PMID 8456302.
Chen Y, Wang S, Lu S (February 2014). "DNA Immunization for HIV Vaccine Development". Vaccines. 2 (1): 138–159. doi:10.3390/vaccines2010138. PMC 4494200. PMID 26344472.
Ledgerwood JE, Pierson TC, Hubka SA, Desai N, Rucker S, Gordon IJ, et al. (May 2011). "A West Nile virus DNA vaccine utilizing a modified promoter induces neutralizing antibody in younger and older healthy adults in a phase I clinical trial". The Journal of Infectious Diseases. 203 (10): 1396–1404. doi:10.1093/infdis/jir054. PMC 3080891. PMID 21398392.
Kilpatrick AM, Dupuis AP, Chang GJ, Kramer LD (May 2010). "DNA vaccination of American robins (Turdus migratorius) against West Nile virus". Vector Borne and Zoonotic Diseases. 10 (4): 377–380. doi:10.1089/vbz.2009.0029. PMC 2883478. PMID 19874192.
Sedegah M, Hedstrom R, Hobart P, Hoffman SL (October 1994). "Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein". Proceedings of the National Academy of Sciences of the United States of America. 91 (21): 9866–9870. Bibcode:1994PNAS...91.9866S. doi:10.1073/pnas.91.21.9866. JSTOR 2365723. PMC 44918. PMID 7937907.
Harmon BT, Aly AE, Padegimas L, Sesenoglu-Laird O, Cooper MJ, Waszczak BL (May 2014). "Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain". Gene Therapy. 21 (5): 514–521. doi:10.1038/gt.2014.28. PMID 24670994. S2CID 5560134.
Mor G, Klinman DM, Shapiro S, Hagiwara E, Sedegah M, Norman JA, et al. (August 1995). "Complexity of the cytokine and antibody response elicited by immunizing mice with Plasmodium yoelii circumsporozoite protein plasmid DNA". Journal of Immunology. 155 (4): 2039–2046. doi:10.4049/jimmunol.155.4.2039. PMID 7636255. S2CID 37290980.
Leitner WW, Seguin MC, Ballou WR, Seitz JP, Schultz AM, Sheehy MJ, Lyon JA (December 1997). "Immune responses induced by intramuscular or gene gun injection of protective deoxyribonucleic acid vaccines that express the circumsporozoite protein from Plasmodium berghei malaria parasites". Journal of Immunology. 159 (12): 6112–6119. doi:10.4049/jimmunol.159.12.6112. PMID 9550412. S2CID 37685499.
Böhm W, Kuhröber A, Paier T, Mertens T, Reimann J, Schirmbeck R (June 1996). "DNA vector constructs that prime hepatitis B surface antigen-specific cytotoxic T lymphocyte and antibody responses in mice after intramuscular injection". Journal of Immunological Methods. 193 (1): 29–40. doi:10.1016/0022-1759(96)00035-X. PMID 8690928.
Lewis PJ, Babiuk LA (1999). DNA vaccines: a review. Vol. 54. Academic Press. pp. 129–88. doi:10.1016/S0065-3527(08)60367-X. ISBN 978-0-12-039854-6. PMID 10547676. {{cite book}}: |journal= ignored (help)
André S, Seed B, Eberle J, Schraut W, Bültmann A, Haas J (February 1998). "Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage". Journal of Virology. 72 (2): 1497–1503. doi:10.1128/JVI.72.2.1497-1503.1998. PMC 124631. PMID 9445053.
Muthumani K, Zhang D, Dayes NS, Hwang DS, Calarota SA, Choo AY, et al. (September 2003). "Novel engineered HIV-1 East African Clade-A gp160 plasmid construct induces strong humoral and cell-mediated immune responses in vivo". Virology. 314 (1): 134–146. doi:10.1016/S0042-6822(03)00459-8. PMID 14517067.
Oliveira PH, Prather KJ, Prazeres DM, Monteiro GA (September 2009). "Structural instability of plasmid biopharmaceuticals: challenges and implications". Trends in Biotechnology. 27 (9): 503–511. doi:10.1016/j.tibtech.2009.06.004. PMID 19656584.
Oliveira PH, Mairhofer J (September 2013). "Marker-free plasmids for biotechnological applications - implications and perspectives". Trends in Biotechnology. 31 (9): 539–547. doi:10.1016/j.tibtech.2013.06.001. PMID 23830144.
Kutzler MA, Weiner DB (October 2008). "DNA vaccines: ready for prime time?". Nature Reviews. Genetics. 9 (10): 776–788. doi:10.1038/nrg2432. PMC 4317294. PMID 18781156.
Rodriguez F, Zhang J, Whitton JL (November 1997). "DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction". Journal of Virology. 71 (11): 8497–8503. doi:10.1128/JVI.71.11.8497-8503.1997. PMC 192313. PMID 9343207.
Tobery TW, Siliciano RF (March 1997). "Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization". The Journal of Experimental Medicine. 185 (5): 909–920. doi:10.1084/jem.185.5.909. PMC 2196169. PMID 9120397.
Huebener N, Fest S, Strandsby A, Michalsky E, Preissner R, Zeng Y, et al. (July 2008). "A rationally designed tyrosine hydroxylase DNA vaccine induces specific antineuroblastoma immunity". Molecular Cancer Therapeutics. 7 (7): 2241–2251. doi:10.1158/1535-7163.MCT-08-0109. PMID 18645033. S2CID 35652424.
Wunderlich G, Moura IC, del Portillo HA (October 2000). "Genetic immunization of BALB/c mice with a plasmid bearing the gene coding for a hybrid merozoite surface protein 1-hepatitis B virus surface protein fusion protects mice against lethal Plasmodium chabaudi chabaudi PC1 infection". Infection and Immunity. 68 (10): 5839–5845. doi:10.1128/IAI.68.10.5839-5845.2000. PMC 101545. PMID 10992493.
Weiner DB, Kennedy RC (July 1999). "Genetic vaccines". Scientific American. 281 (1): 50–57. Bibcode:1999SciAm.281a..50W. doi:10.1038/scientificamerican0799-50. PMID 10396782. Archived from the original on 2009-03-25. Retrieved 2007-11-21.
Widera G, Austin M, Rabussay D, Goldbeck C, Barnett SW, Chen M, et al. (May 2000). "Increased DNA vaccine delivery and immunogenicity by electroporation in vivo". Journal of Immunology. 164 (9): 4635–4640. doi:10.4049/jimmunol.164.9.4635. PMID 10779767.
Daheshia M, Kuklin N, Kanangat S, Manickan E, Rouse BT (August 1997). "Suppression of ongoing ocular inflammatory disease by topical administration of plasmid DNA encoding IL-10". Journal of Immunology. 159 (4): 1945–1952. doi:10.4049/jimmunol.159.4.1945. PMID 9257860. S2CID 43203331.
Chen Y, Webster RG, Woodland DL (March 1998). "Induction of CD8+ T cell responses to dominant and subdominant epitopes and protective immunity to Sendai virus infection by DNA vaccination". Journal of Immunology. 160 (5): 2425–2432. doi:10.4049/jimmunol.160.5.2425. PMID 9498786. S2CID 2250871.
Lode HN, Huebener N, Zeng Y, Fest S, Weixler S, Gaedicke G (December 2004). "DNA minigene vaccination for adjuvant neuroblastoma therapy". Annals of the New York Academy of Sciences. 1028 (1): 113–121. Bibcode:2004NYASA1028..113L. doi:10.1196/annals.1322.012. PMID 15650237. S2CID 27240738.
Sizemore DR, Branstrom AA, Sadoff JC (October 1995). "Attenuated Shigella as a DNA delivery vehicle for DNA-mediated immunization". Science. 270 (5234): 299–302. Bibcode:1995Sci...270..299S. doi:10.1126/science.270.5234.299. PMID 7569980. S2CID 12532901.
Jones CH, Ravikrishnan A, Chen M, Reddinger R, Kamal Ahmadi M, Rane S, et al. (August 2014). "Hybrid biosynthetic gene therapy vector development and dual engineering capacity". Proceedings of the National Academy of Sciences of the United States of America. 111 (34): 12360–12365. Bibcode:2014PNAS..11112360J. doi:10.1073/pnas.1411355111. PMC 4151754. PMID 25114239.
Barry MA, Lai WC, Johnston SA (October 1995). "Protection against mycoplasma infection using expression-library immunization". Nature. 377 (6550): 632–635. Bibcode:1995Natur.377..632B. doi:10.1038/377632a0. PMID 7566175. S2CID 4306972.
Fynan EF, Webster RG, Fuller DH, Haynes JR, Santoro JC, Robinson HL (December 1993). "DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations". Proceedings of the National Academy of Sciences of the United States of America. 90 (24): 11478–11482. Bibcode:1993PNAS...9011478F. doi:10.1073/pnas.90.24.11478. PMC 48007. PMID 8265577.
Feltquate DM, Heaney S, Webster RG, Robinson HL (March 1997). "Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization". Journal of Immunology. 158 (5): 2278–2284. doi:10.4049/jimmunol.158.5.2278. PMID 9036975. S2CID 41368723.
Boyle CM, Morin M, Webster RG, Robinson HL (December 1996). "Role of different lymphoid tissues in the initiation and maintenance of DNA-raised antibody responses to the influenza virus H1 glycoprotein". Journal of Virology. 70 (12): 9074–9078. doi:10.1128/JVI.70.12.9074-9078.1996. PMC 191015. PMID 8971047.
Sällberg M, Townsend K, Chen M, O'Dea J, Banks T, Jolly DJ, et al. (July 1997). "Characterization of humoral and CD4+ cellular responses after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens". Journal of Virology. 71 (7): 5295–5303. doi:10.1128/JVI.71.7.5295-5303.1997. PMC 191766. PMID 9188598.
Banchereau J, Steinman RM (March 1998). "Dendritic cells and the control of immunity". Nature. 392 (6673): 245–252. Bibcode:1998Natur.392..245B. doi:10.1038/32588. PMID 9521319. S2CID 4388748.
Jakob T, Walker PS, Krieg AM, Udey MC, Vogel JC (September 1998). "Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA". Journal of Immunology. 161 (6): 3042–3049. doi:10.4049/jimmunol.161.6.3042. PMID 9743369. S2CID 35107733.
Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman M, et al. (May 1996). "Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization". Proceedings of the National Academy of Sciences of the United States of America. 93 (10): 5141–5145. Bibcode:1996PNAS...93.5141R. doi:10.1073/pnas.93.10.5141. PMC 39421. PMID 8643542.
Fu TM, Friedman A, Ulmer JB, Liu MA, Donnelly JJ (April 1997). "Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization". Journal of Virology. 71 (4): 2715–2721. doi:10.1128/JVI.71.4.2715-2721.1997. PMC 191393. PMID 9060624.
Restifo NP, Bacík I, Irvine KR, Yewdell JW, McCabe BJ, Anderson RW, et al. (May 1995). "Antigen processing in vivo and the elicitation of primary CTL responses". Journal of Immunology. 154 (9): 4414–4422. doi:10.4049/jimmunol.154.9.4414. PMC 1952186. PMID 7722298.
Iwasaki A, Stiernholm BJ, Chan AK, Berinstein NL, Barber BH (May 1997). "Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines". Journal of Immunology. 158 (10): 4591–4601. doi:10.4049/jimmunol.158.10.4591. PMID 9144471. S2CID 41779568.
Weiss WR, Ishii KJ, Hedstrom RC, Sedegah M, Ichino M, Barnhart K, et al. (September 1998). "A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by a malaria DNA vaccine". Journal of Immunology. 161 (5): 2325–2332. doi:10.4049/jimmunol.161.5.2325. PMID 9725227. S2CID 21038927.
Tsuji T, Hamajima K, Fukushima J, Xin KQ, Ishii N, Aoki I, et al. (April 1997). "Enhancement of cell-mediated immunity against HIV-1 induced by coinnoculation of plasmid-encoded HIV-1 antigen with plasmid expressing IL-12". Journal of Immunology. 158 (8): 4008–4013. doi:10.4049/jimmunol.158.8.4008. PMID 9103472. S2CID 38099483.
Justewicz DM, Webster RG (October 1996). "Long-term maintenance of B cell immunity to influenza virus hemagglutinin in mice following DNA-based immunization". Virology. 224 (1): 10–17. doi:10.1006/viro.1996.0501. PMID 8862394.
Mancini-Bourgine M, Fontaine H, Bréchot C, Pol S, Michel ML (May 2006). "Immunogenicity of a hepatitis B DNA vaccine administered to chronic HBV carriers". Vaccine. 24 (21): 4482–4489. doi:10.1016/j.vaccine.2005.08.013. PMID 16310901.
Wolff JA, Dowty ME, Jiao S, Repetto G, Berg RK, Ludtke JJ, et al. (December 1992). "Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscle". Journal of Cell Science. 103. 103 (4): 1249–1259. doi:10.1242/jcs.103.4.1249. PMID 1487500.
Anderson RG, Kamen BA, Rothberg KG, Lacey SW (January 1992). "Potocytosis: sequestration and transport of small molecules by caveolae". Science. 255 (5043): 410–411. Bibcode:1992Sci...255..410A. doi:10.1126/science.1310359. PMID 1310359.
Casares S, Inaba K, Brumeanu TD, Steinman RM, Bona CA (November 1997). "Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope". The Journal of Experimental Medicine. 186 (9): 1481–1486. doi:10.1084/jem.186.9.1481. PMC 2199124. PMID 9348305.
Bennett RM, Gabor GT, Merritt MM (December 1985). "DNA binding to human leukocytes. Evidence for a receptor-mediated association, internalization, and degradation of DNA". The Journal of Clinical Investigation. 76 (6): 2182–2190. doi:10.1172/JCI112226. PMC 424340. PMID 3001145.
Bennet RM, Hefeneider SH, Bakke A, Merritt M, Smith CA, Mourich D, Heinrich MC (May 1988). "The production and characterization of murine monoclonal antibodies to a DNA receptor on human leukocytes". Journal of Immunology. 140 (9): 2937–2942. doi:10.4049/jimmunol.140.9.2937. PMID 2452195. S2CID 22923379.
Corr M, Lee DJ, Carson DA, Tighe H (October 1996). "Gene vaccination with naked plasmid DNA: mechanism of CTL priming". The Journal of Experimental Medicine. 184 (4): 1555–1560. doi:10.1084/jem.184.4.1555. PMC 2192808. PMID 8879229.
Chattergoon MA, Robinson TM, Boyer JD, Weiner DB (June 1998). "Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/antigen-presenting cells". Journal of Immunology. 160 (12): 5707–5718. doi:10.4049/jimmunol.160.12.5707. PMID 9637479. S2CID 33499198.
Torres CA, Iwasaki A, Barber BH, Robinson HL (May 1997). "Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations". Journal of Immunology. 158 (10): 4529–4532. doi:10.4049/jimmunol.158.10.4529. PMID 9144463. S2CID 45069087.
Franco A, Guidotti LG, Hobbs MV, Pasquetto V, Chisari FV (August 1997). "Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice". Journal of Immunology. 159 (4): 2001–2008. doi:10.4049/jimmunol.159.4.2001. PMID 9257867. S2CID 20528634.
Mancini M, Hadchouel M, Davis HL, Whalen RG, Tiollais P, Michel ML (October 1996). "DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state". Proceedings of the National Academy of Sciences of the United States of America. 93 (22): 12496–12501. Bibcode:1996PNAS...9312496M. doi:10.1073/pnas.93.22.12496. PMC 38020. PMID 8901610.
Doolan DL, Hoffman SL (July 1999). "IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model". Journal of Immunology. 163 (2): 884–892. doi:10.4049/jimmunol.163.2.884. PMID 10395683. S2CID 41651105.
Cardoso AI, Blixenkrone-Moller M, Fayolle J, Liu M, Buckland R, Wild TF (November 1996). "Immunization with plasmid DNA encoding for the measles virus hemagglutinin and nucleoprotein leads to humoral and cell-mediated immunity". Virology. 225 (2): 293–299. doi:10.1006/viro.1996.0603. PMID 8918915.
Sato Y, Roman M, Tighe H, Lee D, Corr M, Nguyen MD, et al. (July 1996). "Immunostimulatory DNA sequences necessary for effective intradermal gene immunization". Science. 273 (5273): 352–354. Bibcode:1996Sci...273..352S. doi:10.1126/science.273.5273.352. PMID 8662521. S2CID 9333197.
Weiss R, Leitner WW, Scheiblhofer S, Chen D, Bernhaupt A, Mostböck S, et al. (October 2000). "Genetic vaccination against malaria infection by intradermal and epidermal injections of a plasmid containing the gene encoding the Plasmodium berghei circumsporozoite protein". Infection and Immunity. 68 (10): 5914–5919. doi:10.1128/IAI.68.10.5914-5919.2000. PMC 101554. PMID 10992502.
Sedegah M, Weiss W, Sacci JB, Charoenvit Y, Hedstrom R, Gowda K, et al. (June 2000). "Improving protective immunity induced by DNA-based immunization: priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus". Journal of Immunology. 164 (11): 5905–5912. doi:10.4049/jimmunol.164.11.5905. PMID 10820272.
Barouch DH, Santra S, Steenbeke TD, Zheng XX, Perry HC, Davies ME, et al. (August 1998). "Augmentation and suppression of immune responses to an HIV-1 DNA vaccine by plasmid cytokine/Ig administration". Journal of Immunology. 161 (4): 1875–1882. doi:10.4049/jimmunol.161.4.1875. PMID 9712056. S2CID 36488254.
Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, et al. (April 1995). "CpG motifs in bacterial DNA trigger direct B-cell activation". Nature. 374 (6522): 546–549. Bibcode:1995Natur.374..546K. doi:10.1038/374546a0. PMID 7700380. S2CID 4261304.
Klinman DM, Yamshchikov G, Ishigatsubo Y (April 1997). "Contribution of CpG motifs to the immunogenicity of DNA vaccines". Journal of Immunology. 158 (8): 3635–3639. doi:10.4049/jimmunol.158.8.3635. PMID 9103425. S2CID 41861994.
Krieg AM, Wu T, Weeratna R, Efler SM, Love-Homan L, Yang L, et al. (October 1998). "Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs". Proceedings of the National Academy of Sciences of the United States of America. 95 (21): 12631–12636. Bibcode:1998PNAS...9512631K. doi:10.1073/pnas.95.21.12631. PMC 22882. PMID 9770537.
Klinman DM, Yi AK, Beaucage SL, Conover J, Krieg AM (April 1996). "CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma". Proceedings of the National Academy of Sciences of the United States of America. 93 (7): 2879–2883. Bibcode:1996PNAS...93.2879K. doi:10.1073/pnas.93.7.2879. PMC 39727. PMID 8610135.
Yi AK, Chace JH, Cowdery JS, Krieg AM (January 1996). "IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides". Journal of Immunology. 156 (2): 558–564. doi:10.4049/jimmunol.156.2.558. PMID 8543806. S2CID 42145608.
Barwick BG, Scharer CD, Martinez RJ, Price MJ, Wein AN, Haines RR, et al. (May 2018). "B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation". Nature Communications. 9 (1): 1900. Bibcode:2018NatCo...9.1900B. doi:10.1038/s41467-018-04234-4. PMC 5953949. PMID 29765016.
Letvin NL, Montefiori DC, Yasutomi Y, Perry HC, Davies ME, Lekutis C, et al. (August 1997). "Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination". Proceedings of the National Academy of Sciences of the United States of America. 94 (17): 9378–9383. Bibcode:1997PNAS...94.9378L. doi:10.1073/pnas.94.17.9378. PMC 23198. PMID 9256490.
Sedegah M, Jones TR, Kaur M, Hedstrom R, Hobart P, Tine JA, Hoffman SL (June 1998). "Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine". Proceedings of the National Academy of Sciences of the United States of America. 95 (13): 7648–7653. Bibcode:1998PNAS...95.7648S. doi:10.1073/pnas.95.13.7648. PMC 22711. PMID 9636204.
Rogers WO, Baird JK, Kumar A, Tine JA, Weiss W, Aguiar JC, et al. (September 2001). "Multistage multiantigen heterologous prime boost vaccine for Plasmodium knowlesi malaria provides partial protection in rhesus macaques". Infection and Immunity. 69 (9): 5565–5572. doi:10.1128/IAI.69.9.5565-5572.2001. PMC 98670. PMID 11500430.

harvard.edu

ui.adsabs.harvard.edu

Paoletti E, Lipinskas BR, Samsonoff C, Mercer S, Panicali D (January 1984). "Construction of live vaccines using genetically engineered poxviruses: biological activity of vaccinia virus recombinants expressing the hepatitis B virus surface antigen and the herpes simplex virus glycoprotein D". Proceedings of the National Academy of Sciences of the United States of America. 81 (1): 193–197. Bibcode:1984PNAS...81..193P. doi:10.1073/pnas.81.1.193. PMC 344637. PMID 6320164.
Ulmer JB, Donnelly JJ, Parker SE, Rhodes GH, Felgner PL, Dwarki VJ, et al. (March 1993). "Heterologous protection against influenza by injection of DNA encoding a viral protein". Science. 259 (5102): 1745–1749. Bibcode:1993Sci...259.1745U. doi:10.1126/science.8456302. PMID 8456302.
Sedegah M, Hedstrom R, Hobart P, Hoffman SL (October 1994). "Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein". Proceedings of the National Academy of Sciences of the United States of America. 91 (21): 9866–9870. Bibcode:1994PNAS...91.9866S. doi:10.1073/pnas.91.21.9866. JSTOR 2365723. PMC 44918. PMID 7937907.
Weiner DB, Kennedy RC (July 1999). "Genetic vaccines". Scientific American. 281 (1): 50–57. Bibcode:1999SciAm.281a..50W. doi:10.1038/scientificamerican0799-50. PMID 10396782. Archived from the original on 2009-03-25. Retrieved 2007-11-21.
Lode HN, Huebener N, Zeng Y, Fest S, Weixler S, Gaedicke G (December 2004). "DNA minigene vaccination for adjuvant neuroblastoma therapy". Annals of the New York Academy of Sciences. 1028 (1): 113–121. Bibcode:2004NYASA1028..113L. doi:10.1196/annals.1322.012. PMID 15650237. S2CID 27240738.
Sizemore DR, Branstrom AA, Sadoff JC (October 1995). "Attenuated Shigella as a DNA delivery vehicle for DNA-mediated immunization". Science. 270 (5234): 299–302. Bibcode:1995Sci...270..299S. doi:10.1126/science.270.5234.299. PMID 7569980. S2CID 12532901.
Jones CH, Ravikrishnan A, Chen M, Reddinger R, Kamal Ahmadi M, Rane S, et al. (August 2014). "Hybrid biosynthetic gene therapy vector development and dual engineering capacity". Proceedings of the National Academy of Sciences of the United States of America. 111 (34): 12360–12365. Bibcode:2014PNAS..11112360J. doi:10.1073/pnas.1411355111. PMC 4151754. PMID 25114239.
Barry MA, Lai WC, Johnston SA (October 1995). "Protection against mycoplasma infection using expression-library immunization". Nature. 377 (6550): 632–635. Bibcode:1995Natur.377..632B. doi:10.1038/377632a0. PMID 7566175. S2CID 4306972.
Fynan EF, Webster RG, Fuller DH, Haynes JR, Santoro JC, Robinson HL (December 1993). "DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations". Proceedings of the National Academy of Sciences of the United States of America. 90 (24): 11478–11482. Bibcode:1993PNAS...9011478F. doi:10.1073/pnas.90.24.11478. PMC 48007. PMID 8265577.
Banchereau J, Steinman RM (March 1998). "Dendritic cells and the control of immunity". Nature. 392 (6673): 245–252. Bibcode:1998Natur.392..245B. doi:10.1038/32588. PMID 9521319. S2CID 4388748.
Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman M, et al. (May 1996). "Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization". Proceedings of the National Academy of Sciences of the United States of America. 93 (10): 5141–5145. Bibcode:1996PNAS...93.5141R. doi:10.1073/pnas.93.10.5141. PMC 39421. PMID 8643542.
Anderson RG, Kamen BA, Rothberg KG, Lacey SW (January 1992). "Potocytosis: sequestration and transport of small molecules by caveolae". Science. 255 (5043): 410–411. Bibcode:1992Sci...255..410A. doi:10.1126/science.1310359. PMID 1310359.
Mancini M, Hadchouel M, Davis HL, Whalen RG, Tiollais P, Michel ML (October 1996). "DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state". Proceedings of the National Academy of Sciences of the United States of America. 93 (22): 12496–12501. Bibcode:1996PNAS...9312496M. doi:10.1073/pnas.93.22.12496. PMC 38020. PMID 8901610.
Sato Y, Roman M, Tighe H, Lee D, Corr M, Nguyen MD, et al. (July 1996). "Immunostimulatory DNA sequences necessary for effective intradermal gene immunization". Science. 273 (5273): 352–354. Bibcode:1996Sci...273..352S. doi:10.1126/science.273.5273.352. PMID 8662521. S2CID 9333197.
Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, et al. (April 1995). "CpG motifs in bacterial DNA trigger direct B-cell activation". Nature. 374 (6522): 546–549. Bibcode:1995Natur.374..546K. doi:10.1038/374546a0. PMID 7700380. S2CID 4261304.
Krieg AM, Wu T, Weeratna R, Efler SM, Love-Homan L, Yang L, et al. (October 1998). "Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs". Proceedings of the National Academy of Sciences of the United States of America. 95 (21): 12631–12636. Bibcode:1998PNAS...9512631K. doi:10.1073/pnas.95.21.12631. PMC 22882. PMID 9770537.
Klinman DM, Yi AK, Beaucage SL, Conover J, Krieg AM (April 1996). "CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma". Proceedings of the National Academy of Sciences of the United States of America. 93 (7): 2879–2883. Bibcode:1996PNAS...93.2879K. doi:10.1073/pnas.93.7.2879. PMC 39727. PMID 8610135.
Barwick BG, Scharer CD, Martinez RJ, Price MJ, Wein AN, Haines RR, et al. (May 2018). "B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation". Nature Communications. 9 (1): 1900. Bibcode:2018NatCo...9.1900B. doi:10.1038/s41467-018-04234-4. PMC 5953949. PMID 29765016.
Letvin NL, Montefiori DC, Yasutomi Y, Perry HC, Davies ME, Lekutis C, et al. (August 1997). "Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination". Proceedings of the National Academy of Sciences of the United States of America. 94 (17): 9378–9383. Bibcode:1997PNAS...94.9378L. doi:10.1073/pnas.94.17.9378. PMC 23198. PMID 9256490.
Sedegah M, Jones TR, Kaur M, Hedstrom R, Hobart P, Tine JA, Hoffman SL (June 1998). "Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine". Proceedings of the National Academy of Sciences of the United States of America. 95 (13): 7648–7653. Bibcode:1998PNAS...95.7648S. doi:10.1073/pnas.95.13.7648. PMC 22711. PMID 9636204.

jimmunol.org

Mor G, Klinman DM, Shapiro S, Hagiwara E, Sedegah M, Norman JA, et al. (August 1995). "Complexity of the cytokine and antibody response elicited by immunizing mice with Plasmodium yoelii circumsporozoite protein plasmid DNA". Journal of Immunology. 155 (4): 2039–2046. doi:10.4049/jimmunol.155.4.2039. PMID 7636255. S2CID 37290980.
Leitner WW, Seguin MC, Ballou WR, Seitz JP, Schultz AM, Sheehy MJ, Lyon JA (December 1997). "Immune responses induced by intramuscular or gene gun injection of protective deoxyribonucleic acid vaccines that express the circumsporozoite protein from Plasmodium berghei malaria parasites". Journal of Immunology. 159 (12): 6112–6119. doi:10.4049/jimmunol.159.12.6112. PMID 9550412. S2CID 37685499.
Daheshia M, Kuklin N, Kanangat S, Manickan E, Rouse BT (August 1997). "Suppression of ongoing ocular inflammatory disease by topical administration of plasmid DNA encoding IL-10". Journal of Immunology. 159 (4): 1945–1952. doi:10.4049/jimmunol.159.4.1945. PMID 9257860. S2CID 43203331.
Chen Y, Webster RG, Woodland DL (March 1998). "Induction of CD8+ T cell responses to dominant and subdominant epitopes and protective immunity to Sendai virus infection by DNA vaccination". Journal of Immunology. 160 (5): 2425–2432. doi:10.4049/jimmunol.160.5.2425. PMID 9498786. S2CID 2250871.
Feltquate DM, Heaney S, Webster RG, Robinson HL (March 1997). "Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization". Journal of Immunology. 158 (5): 2278–2284. doi:10.4049/jimmunol.158.5.2278. PMID 9036975. S2CID 41368723.
Jakob T, Walker PS, Krieg AM, Udey MC, Vogel JC (September 1998). "Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA". Journal of Immunology. 161 (6): 3042–3049. doi:10.4049/jimmunol.161.6.3042. PMID 9743369. S2CID 35107733.
Restifo NP, Bacík I, Irvine KR, Yewdell JW, McCabe BJ, Anderson RW, et al. (May 1995). "Antigen processing in vivo and the elicitation of primary CTL responses". Journal of Immunology. 154 (9): 4414–4422. doi:10.4049/jimmunol.154.9.4414. PMC 1952186. PMID 7722298.
Iwasaki A, Stiernholm BJ, Chan AK, Berinstein NL, Barber BH (May 1997). "Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines". Journal of Immunology. 158 (10): 4591–4601. doi:10.4049/jimmunol.158.10.4591. PMID 9144471. S2CID 41779568.
Weiss WR, Ishii KJ, Hedstrom RC, Sedegah M, Ichino M, Barnhart K, et al. (September 1998). "A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by a malaria DNA vaccine". Journal of Immunology. 161 (5): 2325–2332. doi:10.4049/jimmunol.161.5.2325. PMID 9725227. S2CID 21038927.
Tsuji T, Hamajima K, Fukushima J, Xin KQ, Ishii N, Aoki I, et al. (April 1997). "Enhancement of cell-mediated immunity against HIV-1 induced by coinnoculation of plasmid-encoded HIV-1 antigen with plasmid expressing IL-12". Journal of Immunology. 158 (8): 4008–4013. doi:10.4049/jimmunol.158.8.4008. PMID 9103472. S2CID 38099483.
Bennet RM, Hefeneider SH, Bakke A, Merritt M, Smith CA, Mourich D, Heinrich MC (May 1988). "The production and characterization of murine monoclonal antibodies to a DNA receptor on human leukocytes". Journal of Immunology. 140 (9): 2937–2942. doi:10.4049/jimmunol.140.9.2937. PMID 2452195. S2CID 22923379.
Chattergoon MA, Robinson TM, Boyer JD, Weiner DB (June 1998). "Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/antigen-presenting cells". Journal of Immunology. 160 (12): 5707–5718. doi:10.4049/jimmunol.160.12.5707. PMID 9637479. S2CID 33499198.
Torres CA, Iwasaki A, Barber BH, Robinson HL (May 1997). "Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations". Journal of Immunology. 158 (10): 4529–4532. doi:10.4049/jimmunol.158.10.4529. PMID 9144463. S2CID 45069087.
Franco A, Guidotti LG, Hobbs MV, Pasquetto V, Chisari FV (August 1997). "Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice". Journal of Immunology. 159 (4): 2001–2008. doi:10.4049/jimmunol.159.4.2001. PMID 9257867. S2CID 20528634.
Doolan DL, Hoffman SL (July 1999). "IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model". Journal of Immunology. 163 (2): 884–892. doi:10.4049/jimmunol.163.2.884. PMID 10395683. S2CID 41651105.
Barouch DH, Santra S, Steenbeke TD, Zheng XX, Perry HC, Davies ME, et al. (August 1998). "Augmentation and suppression of immune responses to an HIV-1 DNA vaccine by plasmid cytokine/Ig administration". Journal of Immunology. 161 (4): 1875–1882. doi:10.4049/jimmunol.161.4.1875. PMID 9712056. S2CID 36488254.
Klinman DM, Yamshchikov G, Ishigatsubo Y (April 1997). "Contribution of CpG motifs to the immunogenicity of DNA vaccines". Journal of Immunology. 158 (8): 3635–3639. doi:10.4049/jimmunol.158.8.3635. PMID 9103425. S2CID 41861994.
Yi AK, Chace JH, Cowdery JS, Krieg AM (January 1996). "IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides". Journal of Immunology. 156 (2): 558–564. doi:10.4049/jimmunol.156.2.558. PMID 8543806. S2CID 42145608.

jstor.org

Sedegah M, Hedstrom R, Hobart P, Hoffman SL (October 1994). "Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein". Proceedings of the National Academy of Sciences of the United States of America. 91 (21): 9866–9870. Bibcode:1994PNAS...91.9866S. doi:10.1073/pnas.91.21.9866. JSTOR 2365723. PMC 44918. PMID 7937907.

nih.gov

pubmed.ncbi.nlm.nih.gov

Liu S, Wang S, Lu S (April 2016). "DNA immunization as a technology platform for monoclonal antibody induction". Emerging Microbes & Infections. 5 (4): e33. doi:10.1038/emi.2016.27. PMC 4855071. PMID 27048742.
Khan KH (March 2013). "DNA vaccines: roles against diseases". Germs. 3 (1): 26–35. doi:10.11599/germs.2013.1034. PMC 3882840. PMID 24432284.
Alarcon JB, Waine GW, McManus DP (1999). "DNA Vaccines: Technology and Application as Anti-parasite and Anti-microbial Agents". Advances in Parasitology Volume 42. Vol. 42. pp. 343–410. doi:10.1016/S0065-308X(08)60152-9. ISBN 9780120317424. PMID 10050276.
Robinson HL, Pertmer TM (2000). DNA vaccines for viral infections: basic studies and applications. Advances in Virus Research. Vol. 55. pp. 1–74. doi:10.1016/S0065-3527(00)55001-5. ISBN 9780120398553. PMID 11050940.
White LO, Gibb E, Newham HC, Richardson MD, Warren RC (July 1979). "Comparison of the growth of virulent and attenuated strains of Candida albicans in the kidneys of normal and cortison-treated mice by chitin assay". Mycopathologia. 67 (3): 173–177. doi:10.1007/bf00470753. PMID 384256. S2CID 31914107.
Paoletti E, Lipinskas BR, Samsonoff C, Mercer S, Panicali D (January 1984). "Construction of live vaccines using genetically engineered poxviruses: biological activity of vaccinia virus recombinants expressing the hepatitis B virus surface antigen and the herpes simplex virus glycoprotein D". Proceedings of the National Academy of Sciences of the United States of America. 81 (1): 193–197. Bibcode:1984PNAS...81..193P. doi:10.1073/pnas.81.1.193. PMC 344637. PMID 6320164.
Ulmer JB, Donnelly JJ, Parker SE, Rhodes GH, Felgner PL, Dwarki VJ, et al. (March 1993). "Heterologous protection against influenza by injection of DNA encoding a viral protein". Science. 259 (5102): 1745–1749. Bibcode:1993Sci...259.1745U. doi:10.1126/science.8456302. PMID 8456302.
Chen Y, Wang S, Lu S (February 2014). "DNA Immunization for HIV Vaccine Development". Vaccines. 2 (1): 138–159. doi:10.3390/vaccines2010138. PMC 4494200. PMID 26344472.
Ledgerwood JE, Pierson TC, Hubka SA, Desai N, Rucker S, Gordon IJ, et al. (May 2011). "A West Nile virus DNA vaccine utilizing a modified promoter induces neutralizing antibody in younger and older healthy adults in a phase I clinical trial". The Journal of Infectious Diseases. 203 (10): 1396–1404. doi:10.1093/infdis/jir054. PMC 3080891. PMID 21398392.
Kilpatrick AM, Dupuis AP, Chang GJ, Kramer LD (May 2010). "DNA vaccination of American robins (Turdus migratorius) against West Nile virus". Vector Borne and Zoonotic Diseases. 10 (4): 377–380. doi:10.1089/vbz.2009.0029. PMC 2883478. PMID 19874192.
Sedegah M, Hedstrom R, Hobart P, Hoffman SL (October 1994). "Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein". Proceedings of the National Academy of Sciences of the United States of America. 91 (21): 9866–9870. Bibcode:1994PNAS...91.9866S. doi:10.1073/pnas.91.21.9866. JSTOR 2365723. PMC 44918. PMID 7937907.
Harmon BT, Aly AE, Padegimas L, Sesenoglu-Laird O, Cooper MJ, Waszczak BL (May 2014). "Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain". Gene Therapy. 21 (5): 514–521. doi:10.1038/gt.2014.28. PMID 24670994. S2CID 5560134.
Mor G, Klinman DM, Shapiro S, Hagiwara E, Sedegah M, Norman JA, et al. (August 1995). "Complexity of the cytokine and antibody response elicited by immunizing mice with Plasmodium yoelii circumsporozoite protein plasmid DNA". Journal of Immunology. 155 (4): 2039–2046. doi:10.4049/jimmunol.155.4.2039. PMID 7636255. S2CID 37290980.
Leitner WW, Seguin MC, Ballou WR, Seitz JP, Schultz AM, Sheehy MJ, Lyon JA (December 1997). "Immune responses induced by intramuscular or gene gun injection of protective deoxyribonucleic acid vaccines that express the circumsporozoite protein from Plasmodium berghei malaria parasites". Journal of Immunology. 159 (12): 6112–6119. doi:10.4049/jimmunol.159.12.6112. PMID 9550412. S2CID 37685499.
Böhm W, Kuhröber A, Paier T, Mertens T, Reimann J, Schirmbeck R (June 1996). "DNA vector constructs that prime hepatitis B surface antigen-specific cytotoxic T lymphocyte and antibody responses in mice after intramuscular injection". Journal of Immunological Methods. 193 (1): 29–40. doi:10.1016/0022-1759(96)00035-X. PMID 8690928.
Lewis PJ, Babiuk LA (1999). DNA vaccines: a review. Vol. 54. Academic Press. pp. 129–88. doi:10.1016/S0065-3527(08)60367-X. ISBN 978-0-12-039854-6. PMID 10547676. {{cite book}}: |journal= ignored (help)
André S, Seed B, Eberle J, Schraut W, Bültmann A, Haas J (February 1998). "Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage". Journal of Virology. 72 (2): 1497–1503. doi:10.1128/JVI.72.2.1497-1503.1998. PMC 124631. PMID 9445053.
Muthumani K, Zhang D, Dayes NS, Hwang DS, Calarota SA, Choo AY, et al. (September 2003). "Novel engineered HIV-1 East African Clade-A gp160 plasmid construct induces strong humoral and cell-mediated immune responses in vivo". Virology. 314 (1): 134–146. doi:10.1016/S0042-6822(03)00459-8. PMID 14517067.
Oliveira PH, Prather KJ, Prazeres DM, Monteiro GA (September 2009). "Structural instability of plasmid biopharmaceuticals: challenges and implications". Trends in Biotechnology. 27 (9): 503–511. doi:10.1016/j.tibtech.2009.06.004. PMID 19656584.
Oliveira PH, Mairhofer J (September 2013). "Marker-free plasmids for biotechnological applications - implications and perspectives". Trends in Biotechnology. 31 (9): 539–547. doi:10.1016/j.tibtech.2013.06.001. PMID 23830144.
Kutzler MA, Weiner DB (October 2008). "DNA vaccines: ready for prime time?". Nature Reviews. Genetics. 9 (10): 776–788. doi:10.1038/nrg2432. PMC 4317294. PMID 18781156.
Rodriguez F, Zhang J, Whitton JL (November 1997). "DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction". Journal of Virology. 71 (11): 8497–8503. doi:10.1128/JVI.71.11.8497-8503.1997. PMC 192313. PMID 9343207.
Tobery TW, Siliciano RF (March 1997). "Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization". The Journal of Experimental Medicine. 185 (5): 909–920. doi:10.1084/jem.185.5.909. PMC 2196169. PMID 9120397.
Huebener N, Fest S, Strandsby A, Michalsky E, Preissner R, Zeng Y, et al. (July 2008). "A rationally designed tyrosine hydroxylase DNA vaccine induces specific antineuroblastoma immunity". Molecular Cancer Therapeutics. 7 (7): 2241–2251. doi:10.1158/1535-7163.MCT-08-0109. PMID 18645033. S2CID 35652424.
Wunderlich G, Moura IC, del Portillo HA (October 2000). "Genetic immunization of BALB/c mice with a plasmid bearing the gene coding for a hybrid merozoite surface protein 1-hepatitis B virus surface protein fusion protects mice against lethal Plasmodium chabaudi chabaudi PC1 infection". Infection and Immunity. 68 (10): 5839–5845. doi:10.1128/IAI.68.10.5839-5845.2000. PMC 101545. PMID 10992493.
Weiner DB, Kennedy RC (July 1999). "Genetic vaccines". Scientific American. 281 (1): 50–57. Bibcode:1999SciAm.281a..50W. doi:10.1038/scientificamerican0799-50. PMID 10396782. Archived from the original on 2009-03-25. Retrieved 2007-11-21.
Widera G, Austin M, Rabussay D, Goldbeck C, Barnett SW, Chen M, et al. (May 2000). "Increased DNA vaccine delivery and immunogenicity by electroporation in vivo". Journal of Immunology. 164 (9): 4635–4640. doi:10.4049/jimmunol.164.9.4635. PMID 10779767.
Daheshia M, Kuklin N, Kanangat S, Manickan E, Rouse BT (August 1997). "Suppression of ongoing ocular inflammatory disease by topical administration of plasmid DNA encoding IL-10". Journal of Immunology. 159 (4): 1945–1952. doi:10.4049/jimmunol.159.4.1945. PMID 9257860. S2CID 43203331.
Chen Y, Webster RG, Woodland DL (March 1998). "Induction of CD8+ T cell responses to dominant and subdominant epitopes and protective immunity to Sendai virus infection by DNA vaccination". Journal of Immunology. 160 (5): 2425–2432. doi:10.4049/jimmunol.160.5.2425. PMID 9498786. S2CID 2250871.
Lode HN, Huebener N, Zeng Y, Fest S, Weixler S, Gaedicke G (December 2004). "DNA minigene vaccination for adjuvant neuroblastoma therapy". Annals of the New York Academy of Sciences. 1028 (1): 113–121. Bibcode:2004NYASA1028..113L. doi:10.1196/annals.1322.012. PMID 15650237. S2CID 27240738.
Sizemore DR, Branstrom AA, Sadoff JC (October 1995). "Attenuated Shigella as a DNA delivery vehicle for DNA-mediated immunization". Science. 270 (5234): 299–302. Bibcode:1995Sci...270..299S. doi:10.1126/science.270.5234.299. PMID 7569980. S2CID 12532901.
Jones CH, Ravikrishnan A, Chen M, Reddinger R, Kamal Ahmadi M, Rane S, et al. (August 2014). "Hybrid biosynthetic gene therapy vector development and dual engineering capacity". Proceedings of the National Academy of Sciences of the United States of America. 111 (34): 12360–12365. Bibcode:2014PNAS..11112360J. doi:10.1073/pnas.1411355111. PMC 4151754. PMID 25114239.
Barry MA, Lai WC, Johnston SA (October 1995). "Protection against mycoplasma infection using expression-library immunization". Nature. 377 (6550): 632–635. Bibcode:1995Natur.377..632B. doi:10.1038/377632a0. PMID 7566175. S2CID 4306972.
Fynan EF, Webster RG, Fuller DH, Haynes JR, Santoro JC, Robinson HL (December 1993). "DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations". Proceedings of the National Academy of Sciences of the United States of America. 90 (24): 11478–11482. Bibcode:1993PNAS...9011478F. doi:10.1073/pnas.90.24.11478. PMC 48007. PMID 8265577.
Feltquate DM, Heaney S, Webster RG, Robinson HL (March 1997). "Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization". Journal of Immunology. 158 (5): 2278–2284. doi:10.4049/jimmunol.158.5.2278. PMID 9036975. S2CID 41368723.
Boyle CM, Morin M, Webster RG, Robinson HL (December 1996). "Role of different lymphoid tissues in the initiation and maintenance of DNA-raised antibody responses to the influenza virus H1 glycoprotein". Journal of Virology. 70 (12): 9074–9078. doi:10.1128/JVI.70.12.9074-9078.1996. PMC 191015. PMID 8971047.
Sällberg M, Townsend K, Chen M, O'Dea J, Banks T, Jolly DJ, et al. (July 1997). "Characterization of humoral and CD4+ cellular responses after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens". Journal of Virology. 71 (7): 5295–5303. doi:10.1128/JVI.71.7.5295-5303.1997. PMC 191766. PMID 9188598.
Banchereau J, Steinman RM (March 1998). "Dendritic cells and the control of immunity". Nature. 392 (6673): 245–252. Bibcode:1998Natur.392..245B. doi:10.1038/32588. PMID 9521319. S2CID 4388748.
Jakob T, Walker PS, Krieg AM, Udey MC, Vogel JC (September 1998). "Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA". Journal of Immunology. 161 (6): 3042–3049. doi:10.4049/jimmunol.161.6.3042. PMID 9743369. S2CID 35107733.
Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman M, et al. (May 1996). "Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization". Proceedings of the National Academy of Sciences of the United States of America. 93 (10): 5141–5145. Bibcode:1996PNAS...93.5141R. doi:10.1073/pnas.93.10.5141. PMC 39421. PMID 8643542.
Fu TM, Friedman A, Ulmer JB, Liu MA, Donnelly JJ (April 1997). "Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization". Journal of Virology. 71 (4): 2715–2721. doi:10.1128/JVI.71.4.2715-2721.1997. PMC 191393. PMID 9060624.
Restifo NP, Bacík I, Irvine KR, Yewdell JW, McCabe BJ, Anderson RW, et al. (May 1995). "Antigen processing in vivo and the elicitation of primary CTL responses". Journal of Immunology. 154 (9): 4414–4422. doi:10.4049/jimmunol.154.9.4414. PMC 1952186. PMID 7722298.
Iwasaki A, Stiernholm BJ, Chan AK, Berinstein NL, Barber BH (May 1997). "Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines". Journal of Immunology. 158 (10): 4591–4601. doi:10.4049/jimmunol.158.10.4591. PMID 9144471. S2CID 41779568.
Weiss WR, Ishii KJ, Hedstrom RC, Sedegah M, Ichino M, Barnhart K, et al. (September 1998). "A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by a malaria DNA vaccine". Journal of Immunology. 161 (5): 2325–2332. doi:10.4049/jimmunol.161.5.2325. PMID 9725227. S2CID 21038927.
Tsuji T, Hamajima K, Fukushima J, Xin KQ, Ishii N, Aoki I, et al. (April 1997). "Enhancement of cell-mediated immunity against HIV-1 induced by coinnoculation of plasmid-encoded HIV-1 antigen with plasmid expressing IL-12". Journal of Immunology. 158 (8): 4008–4013. doi:10.4049/jimmunol.158.8.4008. PMID 9103472. S2CID 38099483.
Justewicz DM, Webster RG (October 1996). "Long-term maintenance of B cell immunity to influenza virus hemagglutinin in mice following DNA-based immunization". Virology. 224 (1): 10–17. doi:10.1006/viro.1996.0501. PMID 8862394.
Mancini-Bourgine M, Fontaine H, Bréchot C, Pol S, Michel ML (May 2006). "Immunogenicity of a hepatitis B DNA vaccine administered to chronic HBV carriers". Vaccine. 24 (21): 4482–4489. doi:10.1016/j.vaccine.2005.08.013. PMID 16310901.
Wolff JA, Dowty ME, Jiao S, Repetto G, Berg RK, Ludtke JJ, et al. (December 1992). "Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscle". Journal of Cell Science. 103. 103 (4): 1249–1259. doi:10.1242/jcs.103.4.1249. PMID 1487500.
Anderson RG, Kamen BA, Rothberg KG, Lacey SW (January 1992). "Potocytosis: sequestration and transport of small molecules by caveolae". Science. 255 (5043): 410–411. Bibcode:1992Sci...255..410A. doi:10.1126/science.1310359. PMID 1310359.
Casares S, Inaba K, Brumeanu TD, Steinman RM, Bona CA (November 1997). "Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope". The Journal of Experimental Medicine. 186 (9): 1481–1486. doi:10.1084/jem.186.9.1481. PMC 2199124. PMID 9348305.
Bennett RM, Gabor GT, Merritt MM (December 1985). "DNA binding to human leukocytes. Evidence for a receptor-mediated association, internalization, and degradation of DNA". The Journal of Clinical Investigation. 76 (6): 2182–2190. doi:10.1172/JCI112226. PMC 424340. PMID 3001145.
Bennet RM, Hefeneider SH, Bakke A, Merritt M, Smith CA, Mourich D, Heinrich MC (May 1988). "The production and characterization of murine monoclonal antibodies to a DNA receptor on human leukocytes". Journal of Immunology. 140 (9): 2937–2942. doi:10.4049/jimmunol.140.9.2937. PMID 2452195. S2CID 22923379.
Corr M, Lee DJ, Carson DA, Tighe H (October 1996). "Gene vaccination with naked plasmid DNA: mechanism of CTL priming". The Journal of Experimental Medicine. 184 (4): 1555–1560. doi:10.1084/jem.184.4.1555. PMC 2192808. PMID 8879229.
Chattergoon MA, Robinson TM, Boyer JD, Weiner DB (June 1998). "Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/antigen-presenting cells". Journal of Immunology. 160 (12): 5707–5718. doi:10.4049/jimmunol.160.12.5707. PMID 9637479. S2CID 33499198.
Torres CA, Iwasaki A, Barber BH, Robinson HL (May 1997). "Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations". Journal of Immunology. 158 (10): 4529–4532. doi:10.4049/jimmunol.158.10.4529. PMID 9144463. S2CID 45069087.
Franco A, Guidotti LG, Hobbs MV, Pasquetto V, Chisari FV (August 1997). "Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice". Journal of Immunology. 159 (4): 2001–2008. doi:10.4049/jimmunol.159.4.2001. PMID 9257867. S2CID 20528634.
Mancini M, Hadchouel M, Davis HL, Whalen RG, Tiollais P, Michel ML (October 1996). "DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state". Proceedings of the National Academy of Sciences of the United States of America. 93 (22): 12496–12501. Bibcode:1996PNAS...9312496M. doi:10.1073/pnas.93.22.12496. PMC 38020. PMID 8901610.
Doolan DL, Hoffman SL (July 1999). "IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model". Journal of Immunology. 163 (2): 884–892. doi:10.4049/jimmunol.163.2.884. PMID 10395683. S2CID 41651105.
Cardoso AI, Blixenkrone-Moller M, Fayolle J, Liu M, Buckland R, Wild TF (November 1996). "Immunization with plasmid DNA encoding for the measles virus hemagglutinin and nucleoprotein leads to humoral and cell-mediated immunity". Virology. 225 (2): 293–299. doi:10.1006/viro.1996.0603. PMID 8918915.
Sato Y, Roman M, Tighe H, Lee D, Corr M, Nguyen MD, et al. (July 1996). "Immunostimulatory DNA sequences necessary for effective intradermal gene immunization". Science. 273 (5273): 352–354. Bibcode:1996Sci...273..352S. doi:10.1126/science.273.5273.352. PMID 8662521. S2CID 9333197.
Weiss R, Leitner WW, Scheiblhofer S, Chen D, Bernhaupt A, Mostböck S, et al. (October 2000). "Genetic vaccination against malaria infection by intradermal and epidermal injections of a plasmid containing the gene encoding the Plasmodium berghei circumsporozoite protein". Infection and Immunity. 68 (10): 5914–5919. doi:10.1128/IAI.68.10.5914-5919.2000. PMC 101554. PMID 10992502.
Sedegah M, Weiss W, Sacci JB, Charoenvit Y, Hedstrom R, Gowda K, et al. (June 2000). "Improving protective immunity induced by DNA-based immunization: priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus". Journal of Immunology. 164 (11): 5905–5912. doi:10.4049/jimmunol.164.11.5905. PMID 10820272.
Barouch DH, Santra S, Steenbeke TD, Zheng XX, Perry HC, Davies ME, et al. (August 1998). "Augmentation and suppression of immune responses to an HIV-1 DNA vaccine by plasmid cytokine/Ig administration". Journal of Immunology. 161 (4): 1875–1882. doi:10.4049/jimmunol.161.4.1875. PMID 9712056. S2CID 36488254.
Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, et al. (April 1995). "CpG motifs in bacterial DNA trigger direct B-cell activation". Nature. 374 (6522): 546–549. Bibcode:1995Natur.374..546K. doi:10.1038/374546a0. PMID 7700380. S2CID 4261304.
Klinman DM, Yamshchikov G, Ishigatsubo Y (April 1997). "Contribution of CpG motifs to the immunogenicity of DNA vaccines". Journal of Immunology. 158 (8): 3635–3639. doi:10.4049/jimmunol.158.8.3635. PMID 9103425. S2CID 41861994.
Krieg AM, Wu T, Weeratna R, Efler SM, Love-Homan L, Yang L, et al. (October 1998). "Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs". Proceedings of the National Academy of Sciences of the United States of America. 95 (21): 12631–12636. Bibcode:1998PNAS...9512631K. doi:10.1073/pnas.95.21.12631. PMC 22882. PMID 9770537.
Klinman DM, Yi AK, Beaucage SL, Conover J, Krieg AM (April 1996). "CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma". Proceedings of the National Academy of Sciences of the United States of America. 93 (7): 2879–2883. Bibcode:1996PNAS...93.2879K. doi:10.1073/pnas.93.7.2879. PMC 39727. PMID 8610135.
Yi AK, Chace JH, Cowdery JS, Krieg AM (January 1996). "IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides". Journal of Immunology. 156 (2): 558–564. doi:10.4049/jimmunol.156.2.558. PMID 8543806. S2CID 42145608.
Barwick BG, Scharer CD, Martinez RJ, Price MJ, Wein AN, Haines RR, et al. (May 2018). "B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation". Nature Communications. 9 (1): 1900. Bibcode:2018NatCo...9.1900B. doi:10.1038/s41467-018-04234-4. PMC 5953949. PMID 29765016.
Letvin NL, Montefiori DC, Yasutomi Y, Perry HC, Davies ME, Lekutis C, et al. (August 1997). "Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination". Proceedings of the National Academy of Sciences of the United States of America. 94 (17): 9378–9383. Bibcode:1997PNAS...94.9378L. doi:10.1073/pnas.94.17.9378. PMC 23198. PMID 9256490.
Sedegah M, Jones TR, Kaur M, Hedstrom R, Hobart P, Tine JA, Hoffman SL (June 1998). "Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine". Proceedings of the National Academy of Sciences of the United States of America. 95 (13): 7648–7653. Bibcode:1998PNAS...95.7648S. doi:10.1073/pnas.95.13.7648. PMC 22711. PMID 9636204.
Rogers WO, Baird JK, Kumar A, Tine JA, Weiss W, Aguiar JC, et al. (September 2001). "Multistage multiantigen heterologous prime boost vaccine for Plasmodium knowlesi malaria provides partial protection in rhesus macaques". Infection and Immunity. 69 (9): 5565–5572. doi:10.1128/IAI.69.9.5565-5572.2001. PMC 98670. PMID 11500430.

ncbi.nlm.nih.gov

Liu S, Wang S, Lu S (April 2016). "DNA immunization as a technology platform for monoclonal antibody induction". Emerging Microbes & Infections. 5 (4): e33. doi:10.1038/emi.2016.27. PMC 4855071. PMID 27048742.
Khan KH (March 2013). "DNA vaccines: roles against diseases". Germs. 3 (1): 26–35. doi:10.11599/germs.2013.1034. PMC 3882840. PMID 24432284.
Paoletti E, Lipinskas BR, Samsonoff C, Mercer S, Panicali D (January 1984). "Construction of live vaccines using genetically engineered poxviruses: biological activity of vaccinia virus recombinants expressing the hepatitis B virus surface antigen and the herpes simplex virus glycoprotein D". Proceedings of the National Academy of Sciences of the United States of America. 81 (1): 193–197. Bibcode:1984PNAS...81..193P. doi:10.1073/pnas.81.1.193. PMC 344637. PMID 6320164.
Chen Y, Wang S, Lu S (February 2014). "DNA Immunization for HIV Vaccine Development". Vaccines. 2 (1): 138–159. doi:10.3390/vaccines2010138. PMC 4494200. PMID 26344472.
Ledgerwood JE, Pierson TC, Hubka SA, Desai N, Rucker S, Gordon IJ, et al. (May 2011). "A West Nile virus DNA vaccine utilizing a modified promoter induces neutralizing antibody in younger and older healthy adults in a phase I clinical trial". The Journal of Infectious Diseases. 203 (10): 1396–1404. doi:10.1093/infdis/jir054. PMC 3080891. PMID 21398392.
Kilpatrick AM, Dupuis AP, Chang GJ, Kramer LD (May 2010). "DNA vaccination of American robins (Turdus migratorius) against West Nile virus". Vector Borne and Zoonotic Diseases. 10 (4): 377–380. doi:10.1089/vbz.2009.0029. PMC 2883478. PMID 19874192.
Sedegah M, Hedstrom R, Hobart P, Hoffman SL (October 1994). "Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein". Proceedings of the National Academy of Sciences of the United States of America. 91 (21): 9866–9870. Bibcode:1994PNAS...91.9866S. doi:10.1073/pnas.91.21.9866. JSTOR 2365723. PMC 44918. PMID 7937907.
André S, Seed B, Eberle J, Schraut W, Bültmann A, Haas J (February 1998). "Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage". Journal of Virology. 72 (2): 1497–1503. doi:10.1128/JVI.72.2.1497-1503.1998. PMC 124631. PMID 9445053.
Kutzler MA, Weiner DB (October 2008). "DNA vaccines: ready for prime time?". Nature Reviews. Genetics. 9 (10): 776–788. doi:10.1038/nrg2432. PMC 4317294. PMID 18781156.
Rodriguez F, Zhang J, Whitton JL (November 1997). "DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction". Journal of Virology. 71 (11): 8497–8503. doi:10.1128/JVI.71.11.8497-8503.1997. PMC 192313. PMID 9343207.
Tobery TW, Siliciano RF (March 1997). "Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization". The Journal of Experimental Medicine. 185 (5): 909–920. doi:10.1084/jem.185.5.909. PMC 2196169. PMID 9120397.
Wunderlich G, Moura IC, del Portillo HA (October 2000). "Genetic immunization of BALB/c mice with a plasmid bearing the gene coding for a hybrid merozoite surface protein 1-hepatitis B virus surface protein fusion protects mice against lethal Plasmodium chabaudi chabaudi PC1 infection". Infection and Immunity. 68 (10): 5839–5845. doi:10.1128/IAI.68.10.5839-5845.2000. PMC 101545. PMID 10992493.
Jones CH, Ravikrishnan A, Chen M, Reddinger R, Kamal Ahmadi M, Rane S, et al. (August 2014). "Hybrid biosynthetic gene therapy vector development and dual engineering capacity". Proceedings of the National Academy of Sciences of the United States of America. 111 (34): 12360–12365. Bibcode:2014PNAS..11112360J. doi:10.1073/pnas.1411355111. PMC 4151754. PMID 25114239.
Fynan EF, Webster RG, Fuller DH, Haynes JR, Santoro JC, Robinson HL (December 1993). "DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations". Proceedings of the National Academy of Sciences of the United States of America. 90 (24): 11478–11482. Bibcode:1993PNAS...9011478F. doi:10.1073/pnas.90.24.11478. PMC 48007. PMID 8265577.
Boyle CM, Morin M, Webster RG, Robinson HL (December 1996). "Role of different lymphoid tissues in the initiation and maintenance of DNA-raised antibody responses to the influenza virus H1 glycoprotein". Journal of Virology. 70 (12): 9074–9078. doi:10.1128/JVI.70.12.9074-9078.1996. PMC 191015. PMID 8971047.
Sällberg M, Townsend K, Chen M, O'Dea J, Banks T, Jolly DJ, et al. (July 1997). "Characterization of humoral and CD4+ cellular responses after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens". Journal of Virology. 71 (7): 5295–5303. doi:10.1128/JVI.71.7.5295-5303.1997. PMC 191766. PMID 9188598.
Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman M, et al. (May 1996). "Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization". Proceedings of the National Academy of Sciences of the United States of America. 93 (10): 5141–5145. Bibcode:1996PNAS...93.5141R. doi:10.1073/pnas.93.10.5141. PMC 39421. PMID 8643542.
Fu TM, Friedman A, Ulmer JB, Liu MA, Donnelly JJ (April 1997). "Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization". Journal of Virology. 71 (4): 2715–2721. doi:10.1128/JVI.71.4.2715-2721.1997. PMC 191393. PMID 9060624.
Restifo NP, Bacík I, Irvine KR, Yewdell JW, McCabe BJ, Anderson RW, et al. (May 1995). "Antigen processing in vivo and the elicitation of primary CTL responses". Journal of Immunology. 154 (9): 4414–4422. doi:10.4049/jimmunol.154.9.4414. PMC 1952186. PMID 7722298.
Casares S, Inaba K, Brumeanu TD, Steinman RM, Bona CA (November 1997). "Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope". The Journal of Experimental Medicine. 186 (9): 1481–1486. doi:10.1084/jem.186.9.1481. PMC 2199124. PMID 9348305.
Bennett RM, Gabor GT, Merritt MM (December 1985). "DNA binding to human leukocytes. Evidence for a receptor-mediated association, internalization, and degradation of DNA". The Journal of Clinical Investigation. 76 (6): 2182–2190. doi:10.1172/JCI112226. PMC 424340. PMID 3001145.
Corr M, Lee DJ, Carson DA, Tighe H (October 1996). "Gene vaccination with naked plasmid DNA: mechanism of CTL priming". The Journal of Experimental Medicine. 184 (4): 1555–1560. doi:10.1084/jem.184.4.1555. PMC 2192808. PMID 8879229.
Mancini M, Hadchouel M, Davis HL, Whalen RG, Tiollais P, Michel ML (October 1996). "DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state". Proceedings of the National Academy of Sciences of the United States of America. 93 (22): 12496–12501. Bibcode:1996PNAS...9312496M. doi:10.1073/pnas.93.22.12496. PMC 38020. PMID 8901610.
Weiss R, Leitner WW, Scheiblhofer S, Chen D, Bernhaupt A, Mostböck S, et al. (October 2000). "Genetic vaccination against malaria infection by intradermal and epidermal injections of a plasmid containing the gene encoding the Plasmodium berghei circumsporozoite protein". Infection and Immunity. 68 (10): 5914–5919. doi:10.1128/IAI.68.10.5914-5919.2000. PMC 101554. PMID 10992502.
Krieg AM, Wu T, Weeratna R, Efler SM, Love-Homan L, Yang L, et al. (October 1998). "Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs". Proceedings of the National Academy of Sciences of the United States of America. 95 (21): 12631–12636. Bibcode:1998PNAS...9512631K. doi:10.1073/pnas.95.21.12631. PMC 22882. PMID 9770537.
Klinman DM, Yi AK, Beaucage SL, Conover J, Krieg AM (April 1996). "CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma". Proceedings of the National Academy of Sciences of the United States of America. 93 (7): 2879–2883. Bibcode:1996PNAS...93.2879K. doi:10.1073/pnas.93.7.2879. PMC 39727. PMID 8610135.
Barwick BG, Scharer CD, Martinez RJ, Price MJ, Wein AN, Haines RR, et al. (May 2018). "B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation". Nature Communications. 9 (1): 1900. Bibcode:2018NatCo...9.1900B. doi:10.1038/s41467-018-04234-4. PMC 5953949. PMID 29765016.
Letvin NL, Montefiori DC, Yasutomi Y, Perry HC, Davies ME, Lekutis C, et al. (August 1997). "Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination". Proceedings of the National Academy of Sciences of the United States of America. 94 (17): 9378–9383. Bibcode:1997PNAS...94.9378L. doi:10.1073/pnas.94.17.9378. PMC 23198. PMID 9256490.
Sedegah M, Jones TR, Kaur M, Hedstrom R, Hobart P, Tine JA, Hoffman SL (June 1998). "Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine". Proceedings of the National Academy of Sciences of the United States of America. 95 (13): 7648–7653. Bibcode:1998PNAS...95.7648S. doi:10.1073/pnas.95.13.7648. PMC 22711. PMID 9636204.
Rogers WO, Baird JK, Kumar A, Tine JA, Weiss W, Aguiar JC, et al. (September 2001). "Multistage multiantigen heterologous prime boost vaccine for Plasmodium knowlesi malaria provides partial protection in rhesus macaques". Infection and Immunity. 69 (9): 5565–5572. doi:10.1128/IAI.69.9.5565-5572.2001. PMC 98670. PMID 11500430.

researchgate.net

Henrique Roman Ramos and Paulo Lee Ho. "Developing Snake Antivenom Sera by Genetic Immunization: A Review". Clinical Toxinology in Asia Pacific and Africa. 2: 401–414.

reuters.com

"India gives emergency approval for world's first COVID-19 DNA vaccine". Reuters. 2021-08-20. Retrieved 2021-08-22.

sciamdigital.com

Weiner DB, Kennedy RC (July 1999). "Genetic vaccines". Scientific American. 281 (1): 50–57. Bibcode:1999SciAm.281a..50W. doi:10.1038/scientificamerican0799-50. PMID 10396782. Archived from the original on 2009-03-25. Retrieved 2007-11-21.

semanticscholar.org

api.semanticscholar.org

White LO, Gibb E, Newham HC, Richardson MD, Warren RC (July 1979). "Comparison of the growth of virulent and attenuated strains of Candida albicans in the kidneys of normal and cortison-treated mice by chitin assay". Mycopathologia. 67 (3): 173–177. doi:10.1007/bf00470753. PMID 384256. S2CID 31914107.
Harmon BT, Aly AE, Padegimas L, Sesenoglu-Laird O, Cooper MJ, Waszczak BL (May 2014). "Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain". Gene Therapy. 21 (5): 514–521. doi:10.1038/gt.2014.28. PMID 24670994. S2CID 5560134.
Mor G, Klinman DM, Shapiro S, Hagiwara E, Sedegah M, Norman JA, et al. (August 1995). "Complexity of the cytokine and antibody response elicited by immunizing mice with Plasmodium yoelii circumsporozoite protein plasmid DNA". Journal of Immunology. 155 (4): 2039–2046. doi:10.4049/jimmunol.155.4.2039. PMID 7636255. S2CID 37290980.
Leitner WW, Seguin MC, Ballou WR, Seitz JP, Schultz AM, Sheehy MJ, Lyon JA (December 1997). "Immune responses induced by intramuscular or gene gun injection of protective deoxyribonucleic acid vaccines that express the circumsporozoite protein from Plasmodium berghei malaria parasites". Journal of Immunology. 159 (12): 6112–6119. doi:10.4049/jimmunol.159.12.6112. PMID 9550412. S2CID 37685499.
Huebener N, Fest S, Strandsby A, Michalsky E, Preissner R, Zeng Y, et al. (July 2008). "A rationally designed tyrosine hydroxylase DNA vaccine induces specific antineuroblastoma immunity". Molecular Cancer Therapeutics. 7 (7): 2241–2251. doi:10.1158/1535-7163.MCT-08-0109. PMID 18645033. S2CID 35652424.
Daheshia M, Kuklin N, Kanangat S, Manickan E, Rouse BT (August 1997). "Suppression of ongoing ocular inflammatory disease by topical administration of plasmid DNA encoding IL-10". Journal of Immunology. 159 (4): 1945–1952. doi:10.4049/jimmunol.159.4.1945. PMID 9257860. S2CID 43203331.
Chen Y, Webster RG, Woodland DL (March 1998). "Induction of CD8+ T cell responses to dominant and subdominant epitopes and protective immunity to Sendai virus infection by DNA vaccination". Journal of Immunology. 160 (5): 2425–2432. doi:10.4049/jimmunol.160.5.2425. PMID 9498786. S2CID 2250871.
Lode HN, Huebener N, Zeng Y, Fest S, Weixler S, Gaedicke G (December 2004). "DNA minigene vaccination for adjuvant neuroblastoma therapy". Annals of the New York Academy of Sciences. 1028 (1): 113–121. Bibcode:2004NYASA1028..113L. doi:10.1196/annals.1322.012. PMID 15650237. S2CID 27240738.
Sizemore DR, Branstrom AA, Sadoff JC (October 1995). "Attenuated Shigella as a DNA delivery vehicle for DNA-mediated immunization". Science. 270 (5234): 299–302. Bibcode:1995Sci...270..299S. doi:10.1126/science.270.5234.299. PMID 7569980. S2CID 12532901.
Barry MA, Lai WC, Johnston SA (October 1995). "Protection against mycoplasma infection using expression-library immunization". Nature. 377 (6550): 632–635. Bibcode:1995Natur.377..632B. doi:10.1038/377632a0. PMID 7566175. S2CID 4306972.
Feltquate DM, Heaney S, Webster RG, Robinson HL (March 1997). "Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization". Journal of Immunology. 158 (5): 2278–2284. doi:10.4049/jimmunol.158.5.2278. PMID 9036975. S2CID 41368723.
Banchereau J, Steinman RM (March 1998). "Dendritic cells and the control of immunity". Nature. 392 (6673): 245–252. Bibcode:1998Natur.392..245B. doi:10.1038/32588. PMID 9521319. S2CID 4388748.
Jakob T, Walker PS, Krieg AM, Udey MC, Vogel JC (September 1998). "Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA". Journal of Immunology. 161 (6): 3042–3049. doi:10.4049/jimmunol.161.6.3042. PMID 9743369. S2CID 35107733.
Iwasaki A, Stiernholm BJ, Chan AK, Berinstein NL, Barber BH (May 1997). "Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines". Journal of Immunology. 158 (10): 4591–4601. doi:10.4049/jimmunol.158.10.4591. PMID 9144471. S2CID 41779568.
Weiss WR, Ishii KJ, Hedstrom RC, Sedegah M, Ichino M, Barnhart K, et al. (September 1998). "A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by a malaria DNA vaccine". Journal of Immunology. 161 (5): 2325–2332. doi:10.4049/jimmunol.161.5.2325. PMID 9725227. S2CID 21038927.
Tsuji T, Hamajima K, Fukushima J, Xin KQ, Ishii N, Aoki I, et al. (April 1997). "Enhancement of cell-mediated immunity against HIV-1 induced by coinnoculation of plasmid-encoded HIV-1 antigen with plasmid expressing IL-12". Journal of Immunology. 158 (8): 4008–4013. doi:10.4049/jimmunol.158.8.4008. PMID 9103472. S2CID 38099483.
Bennet RM, Hefeneider SH, Bakke A, Merritt M, Smith CA, Mourich D, Heinrich MC (May 1988). "The production and characterization of murine monoclonal antibodies to a DNA receptor on human leukocytes". Journal of Immunology. 140 (9): 2937–2942. doi:10.4049/jimmunol.140.9.2937. PMID 2452195. S2CID 22923379.
Chattergoon MA, Robinson TM, Boyer JD, Weiner DB (June 1998). "Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/antigen-presenting cells". Journal of Immunology. 160 (12): 5707–5718. doi:10.4049/jimmunol.160.12.5707. PMID 9637479. S2CID 33499198.
Torres CA, Iwasaki A, Barber BH, Robinson HL (May 1997). "Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations". Journal of Immunology. 158 (10): 4529–4532. doi:10.4049/jimmunol.158.10.4529. PMID 9144463. S2CID 45069087.
Franco A, Guidotti LG, Hobbs MV, Pasquetto V, Chisari FV (August 1997). "Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice". Journal of Immunology. 159 (4): 2001–2008. doi:10.4049/jimmunol.159.4.2001. PMID 9257867. S2CID 20528634.
Doolan DL, Hoffman SL (July 1999). "IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model". Journal of Immunology. 163 (2): 884–892. doi:10.4049/jimmunol.163.2.884. PMID 10395683. S2CID 41651105.
Sato Y, Roman M, Tighe H, Lee D, Corr M, Nguyen MD, et al. (July 1996). "Immunostimulatory DNA sequences necessary for effective intradermal gene immunization". Science. 273 (5273): 352–354. Bibcode:1996Sci...273..352S. doi:10.1126/science.273.5273.352. PMID 8662521. S2CID 9333197.
Barouch DH, Santra S, Steenbeke TD, Zheng XX, Perry HC, Davies ME, et al. (August 1998). "Augmentation and suppression of immune responses to an HIV-1 DNA vaccine by plasmid cytokine/Ig administration". Journal of Immunology. 161 (4): 1875–1882. doi:10.4049/jimmunol.161.4.1875. PMID 9712056. S2CID 36488254.
Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, et al. (April 1995). "CpG motifs in bacterial DNA trigger direct B-cell activation". Nature. 374 (6522): 546–549. Bibcode:1995Natur.374..546K. doi:10.1038/374546a0. PMID 7700380. S2CID 4261304.
Klinman DM, Yamshchikov G, Ishigatsubo Y (April 1997). "Contribution of CpG motifs to the immunogenicity of DNA vaccines". Journal of Immunology. 158 (8): 3635–3639. doi:10.4049/jimmunol.158.8.3635. PMID 9103425. S2CID 41861994.
Yi AK, Chace JH, Cowdery JS, Krieg AM (January 1996). "IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides". Journal of Immunology. 156 (2): 558–564. doi:10.4049/jimmunol.156.2.558. PMID 8543806. S2CID 42145608.

technologyreview.com

Regalado A (2 August 2016). "The U.S. government has begun testing its first Zika vaccine in humans". MIT Technology Review Magazine. Retrieved 2016-08-06.

web.archive.org

Weiner DB, Kennedy RC (July 1999). "Genetic vaccines". Scientific American. 281 (1): 50–57. Bibcode:1999SciAm.281a..50W. doi:10.1038/scientificamerican0799-50. PMID 10396782. Archived from the original on 2009-03-25. Retrieved 2007-11-21.

who.int

"DNA vaccines". World Health Organization.

zenodo.org

Sizemore DR, Branstrom AA, Sadoff JC (October 1995). "Attenuated Shigella as a DNA delivery vehicle for DNA-mediated immunization". Science. 270 (5234): 299–302. Bibcode:1995Sci...270..299S. doi:10.1126/science.270.5234.299. PMID 7569980. S2CID 12532901.