Analysis of information sources in references of the Wikipedia article "Darolutamide" in English language version.
In the darolutamide arm, the median (range) value of testosterone was 413 (209.0–1183.0) ng/dl at baseline and increased by 43.3% (5.7–144.0%) to a median (range) of 595.0 (260.0–1500.0) ng/dl at week 24. In the GnRH arm, the median (range) value of testosterone was 333.0 (210.9–844.0) ng/dl at baseline and decreased by –96.0% (–99.6% to –80.8%) to a median (range) of 12.9 (1.2–52.8) ng/dl at week 24. Figure 3 shows the absolute change in testosterone values from baseline over time for the two arms. [...] The median testosterone level increased by 43.4% at 24 wk. In comparison, testosterone increased by 114.3% at week 25 with enzalutamide monotherapy in the phase II trial of enzalutamide. This difference and its potential consequences will need to be studied further.
In the darolutamide arm, the median (range) value of testosterone was 413 (209.0–1183.0) ng/dl at baseline and increased by 43.3% (5.7–144.0%) to a median (range) of 595.0 (260.0–1500.0) ng/dl at week 24. In the GnRH arm, the median (range) value of testosterone was 333.0 (210.9–844.0) ng/dl at baseline and decreased by –96.0% (–99.6% to –80.8%) to a median (range) of 12.9 (1.2–52.8) ng/dl at week 24. Figure 3 shows the absolute change in testosterone values from baseline over time for the two arms. [...] The median testosterone level increased by 43.4% at 24 wk. In comparison, testosterone increased by 114.3% at week 25 with enzalutamide monotherapy in the phase II trial of enzalutamide. This difference and its potential consequences will need to be studied further.