Deliriant (English Wikipedia)

Volgin, A. D.; Yakovlev, O. A.; Demin, K. A.; Alekseeva, P. A.; Kyzar, E. J.; Collins, C.; Nichols, D. E.; Kalueff, A. V. (16 October 2018). "Understanding Central Nervous System Effects of Deliriant Hallucinogenic Drugs through Experimental Animal Models". ACS Chemical Neuroscience. 10 (1): 143–154. doi:10.1021/acschemneuro.8b00433. PMID 30252437. S2CID 52824516.
Lakstygal AM, Kolesnikova TO, Khatsko SL, Zabegalov KN, Volgin AD, Demin KA, Shevyrin VA, Wappler-Guzzetta EA, Kalueff AV (May 2019). "DARK Classics in Chemical Neuroscience: Atropine, Scopolamine, and Other Anticholinergic Deliriant Hallucinogens". ACS Chem Neurosci. 10 (5): 2144–2159. doi:10.1021/acschemneuro.8b00615. PMID 30566832.
Dawson, Andrew H.; Buckley, Nicholas A. (March 2016). "Pharmacological management of anticholinergic delirium - theory, evidence and practice". British Journal of Clinical Pharmacology. 81 (3): 516–524. doi:10.1111/bcp.12839. ISSN 0306-5251. PMC 4767198. PMID 26589572. Delirium is only associated with the antagonism of post‐synaptic M1 receptors and to date other receptor subtypes have not been implicated
Shim KH, Kang MJ, Sharma N, An SS (September 2022). "Beauty of the beast: anticholinergic tropane alkaloids in therapeutics". Nat Prod Bioprospect. 12 (1): 33. doi:10.1007/s13659-022-00357-w. PMC 9478010. PMID 36109439. Antagonism at M1 and M2 receptors have negative impact on memory and cognition [60]. [...] Atropine and scopolamine are non-selective competitive antagonist of muscarinic receptors. Atropine has the highest affinity for subtype M1, followed by M2 and M3 and weak affinity for M4 and M5 [71]. On the other hand, scopolamine has strong affinity for M1-M4 compared to M5 [72] while hyoscyamine binds to M2 only [73].
Volgin AD, Yakovlev OA, Demin KA, Alekseeva PA, Kyzar EJ, Collins C, Nichols DE, Kalueff AV (January 2019). "Understanding Central Nervous System Effects of Deliriant Hallucinogenic Drugs through Experimental Animal Models". ACS Chem Neurosci. 10 (1): 143–154. doi:10.1021/acschemneuro.8b00433. PMID 30252437.
Lessenger JE, Feinberg SD (2008). "Abuse of prescription and over-the-counter medications". Journal of the American Board of Family Medicine. 21 (1): 45–54. doi:10.3122/jabfm.2008.01.070071. PMID 18178702.
Bersani, F. S.; Corazza, O.; Simonato, P.; Mylokosta, A.; Levari, E.; Lovaste, R.; Schifano, F. (2013). "Drops of madness? Recreational misuse of tropicamide collyrium; early warning alerts from Russia and Italy". General Hospital Psychiatry. 35 (5): 571–3. doi:10.1016/j.genhosppsych.2013.04.013. PMID 23706777.
Curran, H. V.; Pooviboonsuk, P.; Dalton, J. A.; Lader, M. H. (January 1998). "Differentiating the effects of centrally acting drugs on arousal and memory: an event-related potential study of scopolamine, lorazepam and diphenhydramine". Psychopharmacology. 135 (1): 27–36. doi:10.1007/s002130050482. PMID 9489931. S2CID 9872819.
Freye E (2010). "Toxicity of Datura Stramonium". Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs. Netherlands: Springer. pp. 217–218. doi:10.1007/978-90-481-2448-0_34. ISBN 978-90-481-2447-3.
Beaver, Kathleen M; Gavin, Thomas J (1998). "Treatment of acute anticholinergic poisoning with physostigmine". The American Journal of Emergency Medicine. 16 (5): 505–507. doi:10.1016/S0735-6757(98)90003-1. PMID 9725967.
Flicker C, Ferris SH, Serby M (1992). "Hypersensitivity to scopolamine in the elderly". Psychopharmacology. 107 (2–3): 437–41. doi:10.1007/bf02245172. PMID 1615141. S2CID 29065240.
Fatur, Karsten (June 2020). ""Hexing Herbs" in Ethnobotanical Perspective: A Historical Review of the Uses of Anticholinergic Solanaceae Plants in Europe". Economic Botany. 74 (2): 140–158. Bibcode:2020EcBot..74..140F. doi:10.1007/s12231-020-09498-w. ISSN 0013-0001. S2CID 220844064.
Griffin WJ, Lin GD (March 2000). "Chemotaxonomy and geographical distribution of tropane alkaloids". Phytochemistry. 53 (6): 623–37. Bibcode:2000PChem..53..623G. doi:10.1016/S0031-9422(99)00475-6. PMID 10746874.

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Fatur, Karsten (June 2020). ""Hexing Herbs" in Ethnobotanical Perspective: A Historical Review of the Uses of Anticholinergic Solanaceae Plants in Europe". Economic Botany. 74 (2): 140–158. Bibcode:2020EcBot..74..140F. doi:10.1007/s12231-020-09498-w. ISSN 0013-0001. S2CID 220844064.
Griffin WJ, Lin GD (March 2000). "Chemotaxonomy and geographical distribution of tropane alkaloids". Phytochemistry. 53 (6): 623–37. Bibcode:2000PChem..53..623G. doi:10.1016/S0031-9422(99)00475-6. PMID 10746874.

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Kennedy, David O. (2014). "The Deliriants - The Nightshade (Solanaceae) Family". Plants and the Human Brain. New York: Oxford University Press. pp. 131–137. ISBN 978-0-19-991401-2. LCCN 2013031617. Archived from the original on 2021-09-17. Retrieved 2021-09-17.

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Bliss, M. (2001). "Datura Plant Poisoning" (PDF). Clinical Toxicology Review. 23 (6). Archived from the original (PDF) on 2021-04-23. Retrieved 2020-04-11.

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Volgin, A. D.; Yakovlev, O. A.; Demin, K. A.; Alekseeva, P. A.; Kyzar, E. J.; Collins, C.; Nichols, D. E.; Kalueff, A. V. (16 October 2018). "Understanding Central Nervous System Effects of Deliriant Hallucinogenic Drugs through Experimental Animal Models". ACS Chemical Neuroscience. 10 (1): 143–154. doi:10.1021/acschemneuro.8b00433. PMID 30252437. S2CID 52824516.
Lakstygal AM, Kolesnikova TO, Khatsko SL, Zabegalov KN, Volgin AD, Demin KA, Shevyrin VA, Wappler-Guzzetta EA, Kalueff AV (May 2019). "DARK Classics in Chemical Neuroscience: Atropine, Scopolamine, and Other Anticholinergic Deliriant Hallucinogens". ACS Chem Neurosci. 10 (5): 2144–2159. doi:10.1021/acschemneuro.8b00615. PMID 30566832.
Dawson, Andrew H.; Buckley, Nicholas A. (March 2016). "Pharmacological management of anticholinergic delirium - theory, evidence and practice". British Journal of Clinical Pharmacology. 81 (3): 516–524. doi:10.1111/bcp.12839. ISSN 0306-5251. PMC 4767198. PMID 26589572. Delirium is only associated with the antagonism of post‐synaptic M1 receptors and to date other receptor subtypes have not been implicated
Shim KH, Kang MJ, Sharma N, An SS (September 2022). "Beauty of the beast: anticholinergic tropane alkaloids in therapeutics". Nat Prod Bioprospect. 12 (1): 33. doi:10.1007/s13659-022-00357-w. PMC 9478010. PMID 36109439. Antagonism at M1 and M2 receptors have negative impact on memory and cognition [60]. [...] Atropine and scopolamine are non-selective competitive antagonist of muscarinic receptors. Atropine has the highest affinity for subtype M1, followed by M2 and M3 and weak affinity for M4 and M5 [71]. On the other hand, scopolamine has strong affinity for M1-M4 compared to M5 [72] while hyoscyamine binds to M2 only [73].
Volgin AD, Yakovlev OA, Demin KA, Alekseeva PA, Kyzar EJ, Collins C, Nichols DE, Kalueff AV (January 2019). "Understanding Central Nervous System Effects of Deliriant Hallucinogenic Drugs through Experimental Animal Models". ACS Chem Neurosci. 10 (1): 143–154. doi:10.1021/acschemneuro.8b00433. PMID 30252437.
Lessenger JE, Feinberg SD (2008). "Abuse of prescription and over-the-counter medications". Journal of the American Board of Family Medicine. 21 (1): 45–54. doi:10.3122/jabfm.2008.01.070071. PMID 18178702.
Bersani, F. S.; Corazza, O.; Simonato, P.; Mylokosta, A.; Levari, E.; Lovaste, R.; Schifano, F. (2013). "Drops of madness? Recreational misuse of tropicamide collyrium; early warning alerts from Russia and Italy". General Hospital Psychiatry. 35 (5): 571–3. doi:10.1016/j.genhosppsych.2013.04.013. PMID 23706777.
Curran, H. V.; Pooviboonsuk, P.; Dalton, J. A.; Lader, M. H. (January 1998). "Differentiating the effects of centrally acting drugs on arousal and memory: an event-related potential study of scopolamine, lorazepam and diphenhydramine". Psychopharmacology. 135 (1): 27–36. doi:10.1007/s002130050482. PMID 9489931. S2CID 9872819.
Reichert S, Lin C, Ong W, Him CC, Hameed S (May 2017). "Million dollar ride: Crime committed during involuntary scopolamine intoxication" (PDF). Canadian Family Physician. 63 (5): 369–370. PMC 5429053. PMID 28500194. Archived (PDF) from the original on 22 April 2021.
Demetriades, A. K.; Wallman, P. D.; McGuiness, A.; Gavalas, M. C. (2005). "Low Cost, High Risk: Accidental Nutmeg Intoxication". Emergency Medicine Journal. 22 (3): 223–225. doi:10.1136/emj.2002.004168. PMC 1726685. PMID 15735280
Ehrenpreis, J. E.; Deslauriers, C; Lank, P; Armstrong, P. K.; Leikin, J. B. (2014). "Nutmeg Poisonings: A Retrospective Review of 10 Years Experience from the Illinois Poison Center, 2001–2011". Journal of Medical Toxicology. 10 (2): 148–151. doi:10.1007/s13181-013-0379-7. PMC 4057546. PMID 24452991
Satora, L.; Pach, D.; Butryn, B.; Hydzik, P.; Balicka-Slusarczyk, B. (June 2005). "Fly agaric (Amanita muscaria) poisoning, case report and review". Toxicon. 45 (7): 941–3. doi:10.1016/j.toxicon.2005.01.005. PMID 15904689
Beaver, Kathleen M; Gavin, Thomas J (1998). "Treatment of acute anticholinergic poisoning with physostigmine". The American Journal of Emergency Medicine. 16 (5): 505–507. doi:10.1016/S0735-6757(98)90003-1. PMID 9725967.
Flicker C, Ferris SH, Serby M (1992). "Hypersensitivity to scopolamine in the elderly". Psychopharmacology. 107 (2–3): 437–41. doi:10.1007/bf02245172. PMID 1615141. S2CID 29065240.
More SV, Kumar H, Cho DY, Yun YS, Choi DK (September 2016). "Toxin-Induced Experimental Models of Learning and Memory Impairment". International Journal of Molecular Sciences. 17 (9): 1447. doi:10.3390/ijms17091447. PMC 5037726. PMID 27598124
Griffin WJ, Lin GD (March 2000). "Chemotaxonomy and geographical distribution of tropane alkaloids". Phytochemistry. 53 (6): 623–37. Bibcode:2000PChem..53..623G. doi:10.1016/S0031-9422(99)00475-6. PMID 10746874.

ncbi.nlm.nih.gov

Dawson, Andrew H.; Buckley, Nicholas A. (March 2016). "Pharmacological management of anticholinergic delirium - theory, evidence and practice". British Journal of Clinical Pharmacology. 81 (3): 516–524. doi:10.1111/bcp.12839. ISSN 0306-5251. PMC 4767198. PMID 26589572. Delirium is only associated with the antagonism of post‐synaptic M1 receptors and to date other receptor subtypes have not been implicated
Shim KH, Kang MJ, Sharma N, An SS (September 2022). "Beauty of the beast: anticholinergic tropane alkaloids in therapeutics". Nat Prod Bioprospect. 12 (1): 33. doi:10.1007/s13659-022-00357-w. PMC 9478010. PMID 36109439. Antagonism at M1 and M2 receptors have negative impact on memory and cognition [60]. [...] Atropine and scopolamine are non-selective competitive antagonist of muscarinic receptors. Atropine has the highest affinity for subtype M1, followed by M2 and M3 and weak affinity for M4 and M5 [71]. On the other hand, scopolamine has strong affinity for M1-M4 compared to M5 [72] while hyoscyamine binds to M2 only [73].
Reichert S, Lin C, Ong W, Him CC, Hameed S (May 2017). "Million dollar ride: Crime committed during involuntary scopolamine intoxication" (PDF). Canadian Family Physician. 63 (5): 369–370. PMC 5429053. PMID 28500194. Archived (PDF) from the original on 22 April 2021.

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Volgin, A. D.; Yakovlev, O. A.; Demin, K. A.; Alekseeva, P. A.; Kyzar, E. J.; Collins, C.; Nichols, D. E.; Kalueff, A. V. (16 October 2018). "Understanding Central Nervous System Effects of Deliriant Hallucinogenic Drugs through Experimental Animal Models". ACS Chemical Neuroscience. 10 (1): 143–154. doi:10.1021/acschemneuro.8b00433. PMID 30252437. S2CID 52824516.
Curran, H. V.; Pooviboonsuk, P.; Dalton, J. A.; Lader, M. H. (January 1998). "Differentiating the effects of centrally acting drugs on arousal and memory: an event-related potential study of scopolamine, lorazepam and diphenhydramine". Psychopharmacology. 135 (1): 27–36. doi:10.1007/s002130050482. PMID 9489931. S2CID 9872819.
Flicker C, Ferris SH, Serby M (1992). "Hypersensitivity to scopolamine in the elderly". Psychopharmacology. 107 (2–3): 437–41. doi:10.1007/bf02245172. PMID 1615141. S2CID 29065240.
Fatur, Karsten (June 2020). ""Hexing Herbs" in Ethnobotanical Perspective: A Historical Review of the Uses of Anticholinergic Solanaceae Plants in Europe". Economic Botany. 74 (2): 140–158. Bibcode:2020EcBot..74..140F. doi:10.1007/s12231-020-09498-w. ISSN 0013-0001. S2CID 220844064.

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Fatur, Karsten (June 2020). ""Hexing Herbs" in Ethnobotanical Perspective: A Historical Review of the Uses of Anticholinergic Solanaceae Plants in Europe". Economic Botany. 74 (2): 140–158. Bibcode:2020EcBot..74..140F. doi:10.1007/s12231-020-09498-w. ISSN 0013-0001. S2CID 220844064.

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Kennedy, David O. (2014). "The Deliriants - The Nightshade (Solanaceae) Family". Plants and the Human Brain. New York: Oxford University Press. pp. 131–137. ISBN 978-0-19-991401-2. LCCN 2013031617. Archived from the original on 2021-09-17. Retrieved 2021-09-17.
Reichert S, Lin C, Ong W, Him CC, Hameed S (May 2017). "Million dollar ride: Crime committed during involuntary scopolamine intoxication" (PDF). Canadian Family Physician. 63 (5): 369–370. PMC 5429053. PMID 28500194. Archived (PDF) from the original on 22 April 2021.
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Hallucinogenic mushrooms an emerging trend case study (PDF). Lisbon: European Monitoring Centre for Drugs and Drug Addiction. 2006. ISBN 978-92-9168-249-2. Archived from the original (PDF) on 2012-03-29. Retrieved 2020-06-04.
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Dawson, Andrew H.; Buckley, Nicholas A. (March 2016). "Pharmacological management of anticholinergic delirium - theory, evidence and practice". British Journal of Clinical Pharmacology. 81 (3): 516–524. doi:10.1111/bcp.12839. ISSN 0306-5251. PMC 4767198. PMID 26589572. Delirium is only associated with the antagonism of post‐synaptic M1 receptors and to date other receptor subtypes have not been implicated
Fatur, Karsten (June 2020). ""Hexing Herbs" in Ethnobotanical Perspective: A Historical Review of the Uses of Anticholinergic Solanaceae Plants in Europe". Economic Botany. 74 (2): 140–158. Bibcode:2020EcBot..74..140F. doi:10.1007/s12231-020-09498-w. ISSN 0013-0001. S2CID 220844064.