References analysis of the Wikipedia article "Diphenhydramine" in the English version

books.google.com

doi.org

Saran JS, Barbano RL, Schult R, Wiegand TJ, Selioutski O (October 2017). "Chronic diphenhydramine abuse and withdrawal: A diagnostic challenge". Neurology. Clinical Practice. 7 (5): 439–441. doi:10.1212/CPJ.0000000000000304. PMC 5874453. PMID 29620065.

Paton DM, Webster DR (1985). "Clinical pharmacokinetics of H1-receptor antagonists (the antihistamines)". Clinical Pharmacokinetics. 10 (6): 477–97. doi:10.2165/00003088-198510060-00002. PMID 2866055. S2CID 33541001.

Simons KJ, Watson WT, Martin TJ, Chen XY, Simons FE (July 1990). "Diphenhydramine: pharmacokinetics and pharmacodynamics in elderly adults, young adults, and children". Journal of Clinical Pharmacology. 30 (7): 665–71. doi:10.1002/j.1552-4604.1990.tb01871.x. PMID 2391399. S2CID 25452263.

Garnett WR (February 1986). "Diphenhydramine". American Pharmacy. NS26 (2): 35–40. doi:10.1016/s0095-9561(16)38634-0. PMID 3962845.

Krystal AD (August 2009). "A compendium of placebo-controlled trials of the risks/benefits of pharmacological treatments for insomnia: the empirical basis for U.S. clinical practice". Sleep Med Rev. 13 (4): 265–74. doi:10.1016/j.smrv.2008.08.001. PMID 19153052.

Thomas A, Nallur DG, Jones N, Deslandes PN (January 2009). "Diphenhydramine abuse and detoxification: a brief review and case report". Journal of Psychopharmacology. 23 (1): 101–5. doi:10.1177/0269881107083809. PMID 18308811. S2CID 45490366.

Smith DW, Peterson MR, DeBerard SC (August 1999). "Local anesthesia. Topical application, local infiltration, and field block". Postgraduate Medicine. 106 (2): 57–60, 64–6. doi:10.3810/pgm.1999.08.650. PMID 10456039.

Banerji A, Long AA, Camargo CA (2007). "Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review". Allergy and Asthma Proceedings. 28 (4): 418–26. doi:10.2500/aap.2007.28.3015. PMID 17883909. S2CID 7596980.

Sheikh A, ten Broek VM, Brown SG, Simons FE (January 2007). "H1-antihistamines for the treatment of anaphylaxis with and without shock". The Cochrane Database of Systematic Reviews. 2007 (1): CD006160. doi:10.1002/14651858.CD006160.pub2. PMC 6517288. PMID 17253584.

Dinndorf PA, McCabe MA, Friedrich S (August 1998). "Risk of abuse of diphenhydramine in children and adolescents with chronic illnesses". The Journal of Pediatrics. 133 (2): 293–5. doi:10.1016/S0022-3476(98)70240-9. PMID 9709726.

Sateia MJ, Buysse DJ, Krystal AD, Neubauer DN, Heald JL (February 2017). "Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline". J Clin Sleep Med. 13 (2): 307–349. doi:10.5664/jcsm.6470. PMC 5263087. PMID 27998379.

De Crescenzo F, D'Alò GL, Ostinelli EG, Ciabattini M, Di Franco V, Watanabe N, et al. (July 2022). "Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis". Lancet. 400 (10347): 170–184. doi:10.1016/S0140-6736(22)00878-9. hdl:11380/1288245. PMID 35843245. S2CID 250536370.

de Leon J, Nikoloff DM (February 2008). "Paradoxical excitation on diphenhydramine may be associated with being a CYP2D6 ultrarapid metabolizer: three case reports". CNS Spectrums. 13 (2): 133–5. doi:10.1017/s109285290001628x. PMID 18227744. S2CID 10856872.

American Academy of Hospice and Palliative Medicine (2013), "Five Things Physicians and Patients Should Question" (PDF), Choosing Wisely: an initiative of the ABIM Foundation, vol. 45, no. 3, American Academy of Hospice and Palliative Medicine, pp. 595–605, doi:10.1016/j.jpainsymman.2012.12.002, PMID 23434175, archived from the original on 1 September 2013, retrieved 17 May 2024, which cites

Smith TJ, Ritter JK, Poklis JL, Fletcher D, Coyne PJ, Dodson P, et al. (May 2012). "ABH gel is not absorbed from the skin of normal volunteers". Journal of Pain and Symptom Management. 43 (5): 961–6. doi:10.1016/j.jpainsymman.2011.05.017. PMID 22560361.
Heisler LK, Zhou L, Bajwa P, Hsu J, Tecott LH (July 2007). "Serotonin 5-HT(2C) receptors regulate anxiety-like behavior". Genes, Brain and Behavior. 6 (5): 491–496. doi:10.1111/j.1601-183X.2007.00316.x. PMID 17451451.
Guaiana G, Gupta S, Chiodo D, Davies SJ, Haederle K, Koesters M (December 2013). "Agomelatine versus other antidepressive agents for major depression". The Cochrane Database of Systematic Reviews (12): CD008851. doi:10.1002/14651858.CD008851.pub2. PMC 11289707. PMID 24343836.
Heine A (November 1996). "Diphenhydramine: a forgotten allergen?". Contact Dermatitis. 35 (5): 311–312. doi:10.1111/j.1600-0536.1996.tb02402.x. PMID 9007386. S2CID 32839996.
Coskey RJ (February 1983). "Contact dermatitis caused by diphenhydramine hydrochloride". Journal of the American Academy of Dermatology. 8 (2): 204–206. doi:10.1016/S0190-9622(83)70024-1. PMID 6219138.
Salahudeen MS, Duffull SB, Nishtala PS (March 2015). "Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review". BMC Geriatrics. 15 (31): 31. doi:10.1186/s12877-015-0029-9. PMC 4377853. PMID 25879993.
Khalifa M, Drolet B, Daleau P, Lefez C, Gilbert M, Plante S, et al. (February 1999). "Block of potassium currents in guinea pig ventricular myocytes and lengthening of cardiac repolarization in man by the histamine H1 receptor antagonist diphenhydramine". The Journal of Pharmacology and Experimental Therapeutics. 288 (2): 858–65. doi:10.1016/S0022-3565(24)38031-0. PMID 9918600.
Cole JB, Stellpflug SJ, Gross EA, Smith SW (December 2011). "Wide complex tachycardia in a pediatric diphenhydramine overdose treated with sodium bicarbonate". Pediatric Emergency Care. 27 (12): 1175–7. doi:10.1097/PEC.0b013e31823b0e47. PMID 22158278. S2CID 5602304.
Zimatkin SM, Anichtchik OV (1999). "Alcohol-histamine interactions". Alcohol and Alcoholism. 34 (2): 141–7. doi:10.1093/alcalc/34.2.141. PMID 10344773.
Tatsumi M, Groshan K, Blakely RD, Richelson E (December 1997). "Pharmacological profile of antidepressants and related compounds at human monoamine transporters". European Journal of Pharmacology. 340 (2–3): 249–58. doi:10.1016/s0014-2999(97)01393-9. PMID 9537821.
Krystal AD, Richelson E, Roth T (August 2013). "Review of the histamine system and the clinical effects of H1 antagonists: basis for a new model for understanding the effects of insomnia medications". Sleep Medicine Reviews. 17 (4): 263–72. doi:10.1016/j.smrv.2012.08.001. PMID 23357028.
Tsuchihashi H, Sasaki T, Kojima S, Nagatomo T (1992). "Binding of [3H]haloperidol to dopamine D2 receptors in the rat striatum". J. Pharm. Pharmacol. 44 (11): 911–4. doi:10.1111/j.2042-7158.1992.tb03235.x. PMID 1361536. S2CID 19420332.
Ghoneim OM, Legere JA, Golbraikh A, Tropsha A, Booth RG (October 2006). "Novel ligands for the human histamine H1 receptor: synthesis, pharmacology, and comparative molecular field analysis studies of 2-dimethylamino-5-(6)-phenyl-1,2,3,4-tetrahydronaphthalenes". Bioorganic & Medicinal Chemistry. 14 (19): 6640–58. doi:10.1016/j.bmc.2006.05.077. PMID 16782354.
Gantz I, Schäffer M, DelValle J, Logsdon C, Campbell V, Uhler M, et al. (1991). "Molecular cloning of a gene encoding the histamine H2 receptor". Proceedings of the National Academy of Sciences of the United States of America. 88 (2): 429–33. Bibcode:1991PNAS...88..429G. doi:10.1073/pnas.88.2.429. PMC 50824. PMID 1703298.
Lovenberg TW, Roland BL, Wilson SJ, Jiang X, Pyati J, Huvar A, et al. (June 1999). "Cloning and functional expression of the human histamine H3 receptor". Molecular Pharmacology. 55 (6): 1101–7. doi:10.1124/mol.55.6.1101. PMID 10347254. S2CID 25542667.
Liu C, Ma X, Jiang X, Wilson SJ, Hofstra CL, Blevitt J, et al. (March 2001). "Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow". Molecular Pharmacology. 59 (3): 420–6. doi:10.1124/mol.59.3.420. PMID 11179434. S2CID 123619.
Bolden C, Cusack B, Richelson E (February 1992). "Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells". The Journal of Pharmacology and Experimental Therapeutics. 260 (2): 576–80. doi:10.1016/S0022-3565(25)11335-9. PMID 1346637.
Kim YS, Shin YK, Lee C, Song J (October 2000). "Block of sodium currents in rat dorsal root ganglion neurons by diphenhydramine". Brain Research. 881 (2): 190–8. doi:10.1016/S0006-8993(00)02860-2. PMID 11036158. S2CID 18560451.
Suessbrich H, Waldegger S, Lang F, Busch AE (April 1996). "Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole". FEBS Letters. 385 (1–2): 77–80. Bibcode:1996FEBSL.385...77S. doi:10.1016/0014-5793(96)00355-9. PMID 8641472. S2CID 40355762.
Khilnani G, Khilnani AK (September 2011). "Inverse agonism and its therapeutic significance". Indian Journal of Pharmacology. 43 (5): 492–501. doi:10.4103/0253-7613.84947. PMC 3195115. PMID 22021988.
Domino EF (1999). "History of modern psychopharmacology: a personal view with an emphasis on antidepressants". Psychosomatic Medicine. 61 (5): 591–8. doi:10.1097/00006842-199909000-00002. PMID 10511010.
Carr KD, Hiller JM, Simon EJ (February 1985). "Diphenhydramine potentiates narcotic but not endogenous opioid analgesia". Neuropeptides. 5 (4–6): 411–4. doi:10.1016/0143-4179(85)90041-1. PMID 2860599. S2CID 45054719.
Horton JR, Sawada K, Nishibori M, Cheng X (October 2005). "Structural basis for inhibition of histamine N-methyltransferase by diverse drugs". Journal of Molecular Biology. 353 (2): 334–344. doi:10.1016/j.jmb.2005.08.040. PMC 4021489. PMID 16168438.
Taylor KM, Snyder SH (May 1972). "Histamine methyltransferase: inhibition and potentiation by antihistamines". Molecular Pharmacology. 8 (3): 300–10. doi:10.1016/S0026-895X(25)12747-8. PMID 4402747.
Wang C, Paul S, Wang K, Hu S, Sun CC (2017). "Relationships among Crystal Structures, Mechanical Properties, and Tableting Performance Probed Using Four Salts of Diphenhydramine". Crystal Growth & Design. 17 (11): 6030–6040. Bibcode:2017CrGrD..17.6030W. doi:10.1021/acs.cgd.7b01153.
Rao DD, Venkat Rao P, Sait SS, Mukkanti K, Chakole D (2009). "Simultaneous Determination of Ibuprofen and Diphenhydramine Citrate in Tablets by Validated LC". Chromatographia. 69 (9–10): 1133–1136. doi:10.1365/s10337-009-0977-3. S2CID 97766056.
Rao DD, Sait SS, Mukkanti K (April 2011). "Development and validation of an UPLC method for rapid determination of ibuprofen and diphenhydramine citrate in the presence of impurities in combined dosage form". Journal of Chromatographic Science. 49 (4): 281–286. doi:10.1093/chrsci/49.4.281. PMID 21439118.
Chan CY, Wallander KA (February 1991). "Diphenhydramine toxicity in three children with varicella-zoster infection". DICP. 25 (2): 130–132. doi:10.1177/106002809102500204. PMID 2058184. S2CID 45456788.
Kamijo Y, Soma K, Sato C, Kurihara K (November 2008). "Fatal diphenhydramine poisoning with increased vascular permeability including late pulmonary congestion refractory to percutaneous cardiovascular support". Clinical Toxicology. 46 (9): 864–868. doi:10.1080/15563650802116151. PMID 18608279. S2CID 43642257.
Scavone JM, Greenblatt DJ, Harmatz JS, Engelhardt N, Shader RI (July 1998). "Pharmacokinetics and pharmacodynamics of diphenhydramine 25 mg in young and elderly volunteers". J Clin Pharmacol. 38 (7): 603–9. doi:10.1002/j.1552-4604.1998.tb04466.x. PMID 9702844. S2CID 24989721.
Gelotte CK, Zimmerman BA, Thompson GA (May 2018). "Single-Dose Pharmacokinetic Study of Diphenhydramine HCl in Children and Adolescents". Clin Pharmacol Drug Dev. 7 (4): 400–407. doi:10.1002/cpdd.391. PMC 5947143. PMID 28967696.
Rogers SC, Pruitt CW, Crouch DJ, Caravati EM (September 2010). "Rapid urine drug screens: diphenhydramine and methadone cross-reactivity". Pediatric Emergency Care. 26 (9): 665–6. doi:10.1097/PEC.0b013e3181f05443. PMID 20838187. S2CID 31581678.
Awdishn RA, Whitmill M, Coba V, Killu K (October 2008). "Serotonin reuptake inhibition by diphenhydramine and concomitant linezolid use can result in serotonin syndrome". Chest. 134 (4 Meeting abstracts): 4C. doi:10.1378/chest.134.4_MeetingAbstracts.c4002. Archived from the original on 11 March 2016. Retrieved 19 March 2013.
Marinetti L, Lehman L, Casto B, Harshbarger K, Kubiczek P, Davis J (October 2005). "Over-the-counter cold medications-postmortem findings in infants and the relationship to cause of death". Journal of Analytical Toxicology. 29 (7): 738–43. doi:10.1093/jat/29.7.738. PMID 16419411.
Halpert AG, Olmstead MC, Beninger RJ (January 2002). "Mechanisms and abuse liability of the anti-histamine dimenhydrinate" (PDF). Neuroscience and Biobehavioral Reviews. 26 (1): 61–7. doi:10.1016/s0149-7634(01)00038-0. PMID 11835984. S2CID 46619422. Archived from the original (PDF) on 2 August 2020. Retrieved 23 December 2017.
Gracious B, Abe N, Sundberg J (December 2010). "The importance of taking a history of over-the-counter medication use: a brief review and case illustration of "PRN" antihistamine dependence in a hospitalized adolescent". Journal of Child and Adolescent Psychopharmacology. 20 (6): 521–4. doi:10.1089/cap.2010.0031. PMC 3025184. PMID 21186972.
Dilsaver SC (February 1988). "Antimuscarinic agents as substances of abuse: a review". Journal of Clinical Psychopharmacology. 8 (1): 14–22. doi:10.1097/00004714-198802000-00003. PMID 3280616. S2CID 31355546.
Mumford GK, Silverman K, Griffiths RR (1996). "Reinforcing, subjective, and performance effects of lorazepam and diphenhydramine in humans". Experimental and Clinical Psychopharmacology. 4 (4): 421–430. doi:10.1037/1064-1297.4.4.421.

nih.gov

pubmed.ncbi.nlm.nih.gov

Garnett WR (February 1986). "Diphenhydramine". American Pharmacy. NS26 (2): 35–40. doi:10.1016/s0095-9561(16)38634-0. PMID 3962845.

Flake ZA, Scalley RD, Bailey AG (March 2004). "Practical selection of antiemetics". American Family Physician. 69 (5): 1169–74. PMID 15023018. Archived from the original on 24 March 2016. Retrieved 10 March 2016.

Spencer JP, Gonzalez LS, Barnhart DJ (July 2001). "Medications in the breast-feeding mother". American Family Physician. 64 (1): 119–26. PMID 11456429.

"Diphenhydramine". Drugs and Lactation Database (LactMed) Internet. Bethesda (MD): National Library of Medicine (US). October 2020. PMID 30000938.

Smith TJ, Ritter JK, Poklis JL, Fletcher D, Coyne PJ, Dodson P, et al. (May 2012). "ABH gel is not absorbed from the skin of normal volunteers". Journal of Pain and Symptom Management. 43 (5): 961–6. doi:10.1016/j.jpainsymman.2011.05.017. PMID 22560361.
Heisler LK, Zhou L, Bajwa P, Hsu J, Tecott LH (July 2007). "Serotonin 5-HT(2C) receptors regulate anxiety-like behavior". Genes, Brain and Behavior. 6 (5): 491–496. doi:10.1111/j.1601-183X.2007.00316.x. PMID 17451451.
Guaiana G, Gupta S, Chiodo D, Davies SJ, Haederle K, Koesters M (December 2013). "Agomelatine versus other antidepressive agents for major depression". The Cochrane Database of Systematic Reviews (12): CD008851. doi:10.1002/14651858.CD008851.pub2. PMC 11289707. PMID 24343836.
Heine A (November 1996). "Diphenhydramine: a forgotten allergen?". Contact Dermatitis. 35 (5): 311–312. doi:10.1111/j.1600-0536.1996.tb02402.x. PMID 9007386. S2CID 32839996.
Coskey RJ (February 1983). "Contact dermatitis caused by diphenhydramine hydrochloride". Journal of the American Academy of Dermatology. 8 (2): 204–206. doi:10.1016/S0190-9622(83)70024-1. PMID 6219138.
Salahudeen MS, Duffull SB, Nishtala PS (March 2015). "Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review". BMC Geriatrics. 15 (31): 31. doi:10.1186/s12877-015-0029-9. PMC 4377853. PMID 25879993.
Sicari V, Zabbo CP (2021). "Diphenhydramine". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 30252266. Archived from the original on 28 May 2022. Retrieved 27 December 2021.
Huynh DA, Abbas M, Dabaja A (2021). Diphenhydramine Toxicity. PMID 32491510.
Khalifa M, Drolet B, Daleau P, Lefez C, Gilbert M, Plante S, et al. (February 1999). "Block of potassium currents in guinea pig ventricular myocytes and lengthening of cardiac repolarization in man by the histamine H1 receptor antagonist diphenhydramine". The Journal of Pharmacology and Experimental Therapeutics. 288 (2): 858–65. doi:10.1016/S0022-3565(24)38031-0. PMID 9918600.
Cole JB, Stellpflug SJ, Gross EA, Smith SW (December 2011). "Wide complex tachycardia in a pediatric diphenhydramine overdose treated with sodium bicarbonate". Pediatric Emergency Care. 27 (12): 1175–7. doi:10.1097/PEC.0b013e31823b0e47. PMID 22158278. S2CID 5602304.
Zimatkin SM, Anichtchik OV (1999). "Alcohol-histamine interactions". Alcohol and Alcoholism. 34 (2): 141–7. doi:10.1093/alcalc/34.2.141. PMID 10344773.
Tatsumi M, Groshan K, Blakely RD, Richelson E (December 1997). "Pharmacological profile of antidepressants and related compounds at human monoamine transporters". European Journal of Pharmacology. 340 (2–3): 249–58. doi:10.1016/s0014-2999(97)01393-9. PMID 9537821.
Krystal AD, Richelson E, Roth T (August 2013). "Review of the histamine system and the clinical effects of H1 antagonists: basis for a new model for understanding the effects of insomnia medications". Sleep Medicine Reviews. 17 (4): 263–72. doi:10.1016/j.smrv.2012.08.001. PMID 23357028.
Tsuchihashi H, Sasaki T, Kojima S, Nagatomo T (1992). "Binding of [3H]haloperidol to dopamine D2 receptors in the rat striatum". J. Pharm. Pharmacol. 44 (11): 911–4. doi:10.1111/j.2042-7158.1992.tb03235.x. PMID 1361536. S2CID 19420332.
Ghoneim OM, Legere JA, Golbraikh A, Tropsha A, Booth RG (October 2006). "Novel ligands for the human histamine H1 receptor: synthesis, pharmacology, and comparative molecular field analysis studies of 2-dimethylamino-5-(6)-phenyl-1,2,3,4-tetrahydronaphthalenes". Bioorganic & Medicinal Chemistry. 14 (19): 6640–58. doi:10.1016/j.bmc.2006.05.077. PMID 16782354.
Gantz I, Schäffer M, DelValle J, Logsdon C, Campbell V, Uhler M, et al. (1991). "Molecular cloning of a gene encoding the histamine H2 receptor". Proceedings of the National Academy of Sciences of the United States of America. 88 (2): 429–33. Bibcode:1991PNAS...88..429G. doi:10.1073/pnas.88.2.429. PMC 50824. PMID 1703298.
Lovenberg TW, Roland BL, Wilson SJ, Jiang X, Pyati J, Huvar A, et al. (June 1999). "Cloning and functional expression of the human histamine H3 receptor". Molecular Pharmacology. 55 (6): 1101–7. doi:10.1124/mol.55.6.1101. PMID 10347254. S2CID 25542667.
Liu C, Ma X, Jiang X, Wilson SJ, Hofstra CL, Blevitt J, et al. (March 2001). "Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow". Molecular Pharmacology. 59 (3): 420–6. doi:10.1124/mol.59.3.420. PMID 11179434. S2CID 123619.
Bolden C, Cusack B, Richelson E (February 1992). "Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells". The Journal of Pharmacology and Experimental Therapeutics. 260 (2): 576–80. doi:10.1016/S0022-3565(25)11335-9. PMID 1346637.
Kim YS, Shin YK, Lee C, Song J (October 2000). "Block of sodium currents in rat dorsal root ganglion neurons by diphenhydramine". Brain Research. 881 (2): 190–8. doi:10.1016/S0006-8993(00)02860-2. PMID 11036158. S2CID 18560451.
Suessbrich H, Waldegger S, Lang F, Busch AE (April 1996). "Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole". FEBS Letters. 385 (1–2): 77–80. Bibcode:1996FEBSL.385...77S. doi:10.1016/0014-5793(96)00355-9. PMID 8641472. S2CID 40355762.
Khilnani G, Khilnani AK (September 2011). "Inverse agonism and its therapeutic significance". Indian Journal of Pharmacology. 43 (5): 492–501. doi:10.4103/0253-7613.84947. PMC 3195115. PMID 22021988.
Domino EF (1999). "History of modern psychopharmacology: a personal view with an emphasis on antidepressants". Psychosomatic Medicine. 61 (5): 591–8. doi:10.1097/00006842-199909000-00002. PMID 10511010.
Carr KD, Hiller JM, Simon EJ (February 1985). "Diphenhydramine potentiates narcotic but not endogenous opioid analgesia". Neuropeptides. 5 (4–6): 411–4. doi:10.1016/0143-4179(85)90041-1. PMID 2860599. S2CID 45054719.
Horton JR, Sawada K, Nishibori M, Cheng X (October 2005). "Structural basis for inhibition of histamine N-methyltransferase by diverse drugs". Journal of Molecular Biology. 353 (2): 334–344. doi:10.1016/j.jmb.2005.08.040. PMC 4021489. PMID 16168438.
Taylor KM, Snyder SH (May 1972). "Histamine methyltransferase: inhibition and potentiation by antihistamines". Molecular Pharmacology. 8 (3): 300–10. doi:10.1016/S0026-895X(25)12747-8. PMID 4402747.
Rao DD, Sait SS, Mukkanti K (April 2011). "Development and validation of an UPLC method for rapid determination of ibuprofen and diphenhydramine citrate in the presence of impurities in combined dosage form". Journal of Chromatographic Science. 49 (4): 281–286. doi:10.1093/chrsci/49.4.281. PMID 21439118.
Chan CY, Wallander KA (February 1991). "Diphenhydramine toxicity in three children with varicella-zoster infection". DICP. 25 (2): 130–132. doi:10.1177/106002809102500204. PMID 2058184. S2CID 45456788.
Kamijo Y, Soma K, Sato C, Kurihara K (November 2008). "Fatal diphenhydramine poisoning with increased vascular permeability including late pulmonary congestion refractory to percutaneous cardiovascular support". Clinical Toxicology. 46 (9): 864–868. doi:10.1080/15563650802116151. PMID 18608279. S2CID 43642257.
Scavone JM, Greenblatt DJ, Harmatz JS, Engelhardt N, Shader RI (July 1998). "Pharmacokinetics and pharmacodynamics of diphenhydramine 25 mg in young and elderly volunteers". J Clin Pharmacol. 38 (7): 603–9. doi:10.1002/j.1552-4604.1998.tb04466.x. PMID 9702844. S2CID 24989721.
Gelotte CK, Zimmerman BA, Thompson GA (May 2018). "Single-Dose Pharmacokinetic Study of Diphenhydramine HCl in Children and Adolescents". Clin Pharmacol Drug Dev. 7 (4): 400–407. doi:10.1002/cpdd.391. PMC 5947143. PMID 28967696.
Rogers SC, Pruitt CW, Crouch DJ, Caravati EM (September 2010). "Rapid urine drug screens: diphenhydramine and methadone cross-reactivity". Pediatric Emergency Care. 26 (9): 665–6. doi:10.1097/PEC.0b013e3181f05443. PMID 20838187. S2CID 31581678.
"Diphenhydramine". Mother To Baby | Fact Sheets [Internet]. National Library of Medicine. January 2023. PMID 35951938. Retrieved 16 April 2024.
Food and Drug Administration, HHS (December 2002). "Labeling of diphenhydramine-containing drug products for over-the-counter human use. Final rule". Federal Register. 67 (235): 72555–9. PMID 12474879. Archived from the original on 5 November 2008.
Marinetti L, Lehman L, Casto B, Harshbarger K, Kubiczek P, Davis J (October 2005). "Over-the-counter cold medications-postmortem findings in infants and the relationship to cause of death". Journal of Analytical Toxicology. 29 (7): 738–43. doi:10.1093/jat/29.7.738. PMID 16419411.
Halpert AG, Olmstead MC, Beninger RJ (January 2002). "Mechanisms and abuse liability of the anti-histamine dimenhydrinate" (PDF). Neuroscience and Biobehavioral Reviews. 26 (1): 61–7. doi:10.1016/s0149-7634(01)00038-0. PMID 11835984. S2CID 46619422. Archived from the original (PDF) on 2 August 2020. Retrieved 23 December 2017.
Gracious B, Abe N, Sundberg J (December 2010). "The importance of taking a history of over-the-counter medication use: a brief review and case illustration of "PRN" antihistamine dependence in a hospitalized adolescent". Journal of Child and Adolescent Psychopharmacology. 20 (6): 521–4. doi:10.1089/cap.2010.0031. PMC 3025184. PMID 21186972.
Dilsaver SC (February 1988). "Antimuscarinic agents as substances of abuse: a review". Journal of Clinical Psychopharmacology. 8 (1): 14–22. doi:10.1097/00004714-198802000-00003. PMID 3280616. S2CID 31355546.

ncbi.nlm.nih.gov

Saran JS, Barbano RL, Schult R, Wiegand TJ, Selioutski O (October 2017). "Chronic diphenhydramine abuse and withdrawal: A diagnostic challenge". Neurology. Clinical Practice. 7 (5): 439–441. doi:10.1212/CPJ.0000000000000304. PMC 5874453. PMID 29620065.
Sheikh A, ten Broek VM, Brown SG, Simons FE (January 2007). "H1-antihistamines for the treatment of anaphylaxis with and without shock". The Cochrane Database of Systematic Reviews. 2007 (1): CD006160. doi:10.1002/14651858.CD006160.pub2. PMC 6517288. PMID 17253584.
Sateia MJ, Buysse DJ, Krystal AD, Neubauer DN, Heald JL (February 2017). "Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline". J Clin Sleep Med. 13 (2): 307–349. doi:10.5664/jcsm.6470. PMC 5263087. PMID 27998379.
Guaiana G, Gupta S, Chiodo D, Davies SJ, Haederle K, Koesters M (December 2013). "Agomelatine versus other antidepressive agents for major depression". The Cochrane Database of Systematic Reviews (12): CD008851. doi:10.1002/14651858.CD008851.pub2. PMC 11289707. PMID 24343836.
Salahudeen MS, Duffull SB, Nishtala PS (March 2015). "Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review". BMC Geriatrics. 15 (31): 31. doi:10.1186/s12877-015-0029-9. PMC 4377853. PMID 25879993.
Sicari V, Zabbo CP (2021). "Diphenhydramine". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 30252266. Archived from the original on 28 May 2022. Retrieved 27 December 2021.
Gantz I, Schäffer M, DelValle J, Logsdon C, Campbell V, Uhler M, et al. (1991). "Molecular cloning of a gene encoding the histamine H2 receptor". Proceedings of the National Academy of Sciences of the United States of America. 88 (2): 429–33. Bibcode:1991PNAS...88..429G. doi:10.1073/pnas.88.2.429. PMC 50824. PMID 1703298.
Khilnani G, Khilnani AK (September 2011). "Inverse agonism and its therapeutic significance". Indian Journal of Pharmacology. 43 (5): 492–501. doi:10.4103/0253-7613.84947. PMC 3195115. PMID 22021988.
Horton JR, Sawada K, Nishibori M, Cheng X (October 2005). "Structural basis for inhibition of histamine N-methyltransferase by diverse drugs". Journal of Molecular Biology. 353 (2): 334–344. doi:10.1016/j.jmb.2005.08.040. PMC 4021489. PMID 16168438.
Gelotte CK, Zimmerman BA, Thompson GA (May 2018). "Single-Dose Pharmacokinetic Study of Diphenhydramine HCl in Children and Adolescents". Clin Pharmacol Drug Dev. 7 (4): 400–407. doi:10.1002/cpdd.391. PMC 5947143. PMID 28967696.
"Diphenhydramine". Mother To Baby | Fact Sheets [Internet]. National Library of Medicine. January 2023. PMID 35951938. Retrieved 16 April 2024.
Gracious B, Abe N, Sundberg J (December 2010). "The importance of taking a history of over-the-counter medication use: a brief review and case illustration of "PRN" antihistamine dependence in a hospitalized adolescent". Journal of Child and Adolescent Psychopharmacology. 20 (6): 521–4. doi:10.1089/cap.2010.0031. PMC 3025184. PMID 21186972.

pubchem.ncbi.nlm.nih.gov

"Diphenhydramine Hydrochloride". PubChem. U.S. National Library of Medicine.
"Diphenhydramine citrate". PubChem. U.S. National Library of Medicine.

dailymed.nlm.nih.gov

"Diphenhydramine- diphenhydramine hydrochloride injection, solution". DailyMed. 11 November 2019. Retrieved 18 May 2024.

ninds.nih.gov

"Restless Legs Syndrome Fact Sheet". National Institute of Neurological Disorders and Stroke. Archived from the original on 28 July 2017. Retrieved 27 August 2019.

nlm.nih.gov

"Diphenhydramine overdose". MedlinePlus Medical Encyclopedia. U.S. National Library of Medicine. Archived from the original on 30 May 2013.

semanticscholar.org

api.semanticscholar.org

Heine A (November 1996). "Diphenhydramine: a forgotten allergen?". Contact Dermatitis. 35 (5): 311–312. doi:10.1111/j.1600-0536.1996.tb02402.x. PMID 9007386. S2CID 32839996.

Cole JB, Stellpflug SJ, Gross EA, Smith SW (December 2011). "Wide complex tachycardia in a pediatric diphenhydramine overdose treated with sodium bicarbonate". Pediatric Emergency Care. 27 (12): 1175–7. doi:10.1097/PEC.0b013e31823b0e47. PMID 22158278. S2CID 5602304.

Tsuchihashi H, Sasaki T, Kojima S, Nagatomo T (1992). "Binding of [3H]haloperidol to dopamine D2 receptors in the rat striatum". J. Pharm. Pharmacol. 44 (11): 911–4. doi:10.1111/j.2042-7158.1992.tb03235.x. PMID 1361536. S2CID 19420332.

Lovenberg TW, Roland BL, Wilson SJ, Jiang X, Pyati J, Huvar A, et al. (June 1999). "Cloning and functional expression of the human histamine H3 receptor". Molecular Pharmacology. 55 (6): 1101–7. doi:10.1124/mol.55.6.1101. PMID 10347254. S2CID 25542667.

Liu C, Ma X, Jiang X, Wilson SJ, Hofstra CL, Blevitt J, et al. (March 2001). "Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow". Molecular Pharmacology. 59 (3): 420–6. doi:10.1124/mol.59.3.420. PMID 11179434. S2CID 123619.

Kim YS, Shin YK, Lee C, Song J (October 2000). "Block of sodium currents in rat dorsal root ganglion neurons by diphenhydramine". Brain Research. 881 (2): 190–8. doi:10.1016/S0006-8993(00)02860-2. PMID 11036158. S2CID 18560451.

Suessbrich H, Waldegger S, Lang F, Busch AE (April 1996). "Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole". FEBS Letters. 385 (1–2): 77–80. Bibcode:1996FEBSL.385...77S. doi:10.1016/0014-5793(96)00355-9. PMID 8641472. S2CID 40355762.

Carr KD, Hiller JM, Simon EJ (February 1985). "Diphenhydramine potentiates narcotic but not endogenous opioid analgesia". Neuropeptides. 5 (4–6): 411–4. doi:10.1016/0143-4179(85)90041-1. PMID 2860599. S2CID 45054719.

Rao DD, Venkat Rao P, Sait SS, Mukkanti K, Chakole D (2009). "Simultaneous Determination of Ibuprofen and Diphenhydramine Citrate in Tablets by Validated LC". Chromatographia. 69 (9–10): 1133–1136. doi:10.1365/s10337-009-0977-3. S2CID 97766056.

Chan CY, Wallander KA (February 1991). "Diphenhydramine toxicity in three children with varicella-zoster infection". DICP. 25 (2): 130–132. doi:10.1177/106002809102500204. PMID 2058184. S2CID 45456788.

Kamijo Y, Soma K, Sato C, Kurihara K (November 2008). "Fatal diphenhydramine poisoning with increased vascular permeability including late pulmonary congestion refractory to percutaneous cardiovascular support". Clinical Toxicology. 46 (9): 864–868. doi:10.1080/15563650802116151. PMID 18608279. S2CID 43642257.

Scavone JM, Greenblatt DJ, Harmatz JS, Engelhardt N, Shader RI (July 1998). "Pharmacokinetics and pharmacodynamics of diphenhydramine 25 mg in young and elderly volunteers". J Clin Pharmacol. 38 (7): 603–9. doi:10.1002/j.1552-4604.1998.tb04466.x. PMID 9702844. S2CID 24989721.

Rogers SC, Pruitt CW, Crouch DJ, Caravati EM (September 2010). "Rapid urine drug screens: diphenhydramine and methadone cross-reactivity". Pediatric Emergency Care. 26 (9): 665–6. doi:10.1097/PEC.0b013e3181f05443. PMID 20838187. S2CID 31581678.

Halpert AG, Olmstead MC, Beninger RJ (January 2002). "Mechanisms and abuse liability of the anti-histamine dimenhydrinate" (PDF). Neuroscience and Biobehavioral Reviews. 26 (1): 61–7. doi:10.1016/s0149-7634(01)00038-0. PMID 11835984. S2CID 46619422. Archived from the original (PDF) on 2 August 2020. Retrieved 23 December 2017.

Dilsaver SC (February 1988). "Antimuscarinic agents as substances of abuse: a review". Journal of Clinical Psychopharmacology. 8 (1): 14–22. doi:10.1097/00004714-198802000-00003. PMID 3280616. S2CID 31355546.

web.archive.org

"Benylin Chesty Coughs (Original) - Summary of Product Characteristics (SmPC)". (emc). 24 February 2022. Archived from the original on 30 December 2022. Retrieved 29 December 2022.

AHFS Drug Information. Published by authority of the Board of Directors of the American Society of Hospital Pharmacists. 1990. Archived from the original on 14 January 2023. Retrieved 9 October 2017.

"Showing Diphenhydramine (DB01075)". DrugBank. Archived from the original on 31 August 2009. Retrieved 5 September 2009.

"Diphenhydramine Hydrochloride". Drugs.com. American Society of Health-System Pharmacists. 6 September 2016. Archived from the original on 15 September 2016. Retrieved 28 September 2016.

Ayd FJ (2000). Lexicon of Psychiatry, Neurology, and the Neurosciences. Lippincott Williams & Wilkins. p. 332. ISBN 978-0-7817-2468-5. Archived from the original on 8 September 2017.

"Diphenhydramine Pregnancy and Breastfeeding Warnings". Drugs.com. Archived from the original on 2 October 2016. Retrieved 28 September 2016.

Dörwald FZ (2013). Lead Optimization for Medicinal Chemists: Pharmacokinetic Properties of Functional Groups and Organic Compounds. John Wiley & Sons. p. 225. ISBN 978-3-527-64565-7. Archived from the original on 2 October 2016.

"Benadryl". Ohio History Central. Archived from the original on 17 October 2016. Retrieved 28 September 2016.

"The Top 300 of 2022". ClinCalc. Archived from the original on 30 August 2024. Retrieved 30 August 2024.

"Diphenhydramine Hydrochloride Monograph". Drugs.com. The American Society of Health-System Pharmacists. Archived from the original on 15 June 2011.

Brown HE, Stoklosa J, Freudenreich O (December 2012). "How to stabilize an acutely psychotic patient" (PDF). Current Psychiatary. 11 (12): 10–16. Archived from the original (PDF) on 14 May 2013.

American Society of Health-System Pharmacists. "Diphenhydramine Hydrochloride". Drugs.com. Archived from the original on 15 September 2016. Retrieved 2 August 2016.

"Diphenhydramine Topical". MedlinePlus. Archived from the original on 10 October 2020. Retrieved 9 October 2020.

Monson K, Schoenstadt A (8 September 2013). "Benadryl Addiction". eMedTV. Archived from the original on 4 January 2014.

Morris R (3 April 2013). "Should parents drug babies on long flights?". BBC News. Archived from the original on 8 March 2021. Retrieved 13 April 2020.

Swanson WS (25 November 2009). "If It Were My Child: No Benadryl for the Plane". Seattle Children's. Archived from the original on 25 February 2021. Retrieved 13 April 2020.

Smith TJ, Ritter JK, Poklis JL, Fletcher D, Coyne PJ, Dodson P, et al. (May 2012). "ABH gel is not absorbed from the skin of normal volunteers". Journal of Pain and Symptom Management. 43 (5): 961–6. doi:10.1016/j.jpainsymman.2011.05.017. PMID 22560361.
Aronson JK (2009). Meyler's Side Effects of Cardiovascular Drugs. Elsevier. p. 623. ISBN 978-0-08-093289-7. Archived from the original on 8 March 2021. Retrieved 4 March 2020.
"Restless Legs Syndrome Fact Sheet". National Institute of Neurological Disorders and Stroke. Archived from the original on 28 July 2017. Retrieved 27 August 2019.
Sicari V, Zabbo CP (2021). "Diphenhydramine". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 30252266. Archived from the original on 28 May 2022. Retrieved 27 December 2021.
"Diphenhydramine overdose". MedlinePlus Medical Encyclopedia. U.S. National Library of Medicine. Archived from the original on 30 May 2013.
"Diphenhydramine and Alcohol / Food Interactions". Drugs.com. Archived from the original on 17 February 2013.
Roth BL, Driscol J. "PDSP K_i Database". Psychoactive Drug Screening Program (PDSP). University of North Carolina at Chapel Hill and the United States National Institute of Mental Health. Archived from the original on 20 April 2019. Retrieved 14 August 2017.
Lopez AM (10 May 2010). "Antihistamine Toxicity". Medscape Reference. WebMD LLC. Archived from the original on 13 October 2010.
Ritchie J (24 September 2007). "UC prof, Benadryl inventor dies". Business Courier of Cincinnati. Archived from the original on 24 December 2008. Retrieved 14 October 2008.
Awdishn RA, Whitmill M, Coba V, Killu K (October 2008). "Serotonin reuptake inhibition by diphenhydramine and concomitant linezolid use can result in serotonin syndrome". Chest. 134 (4 Meeting abstracts): 4C. doi:10.1378/chest.134.4_MeetingAbstracts.c4002. Archived from the original on 11 March 2016. Retrieved 19 March 2013.
"Childrens Benadryl Allergy (solution) Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division". Drugs.com. Archived from the original on 29 July 2020. Retrieved 26 November 2019.
"Is P&G Preparing to Expand ZzzQuil?". Archived from the original on 11 February 2017. Retrieved 10 February 2017.
Food and Drug Administration, HHS (December 2002). "Labeling of diphenhydramine-containing drug products for over-the-counter human use. Final rule". Federal Register. 67 (235): 72555–9. PMID 12474879. Archived from the original on 5 November 2008.
"List of prohibited and controlled drugs according to chapter 96 of the laws of Zambia". The Drug Enforcement Commission ZAMBIA. Archived from the original (DOC) on 16 November 2013. Retrieved 20 March 2013.
"Zambia". Country Information > Zambia. Bureau of Consular Affairs, U.S. Department of State. Archived from the original on 21 July 2015. Retrieved 17 July 2015.
Forest E (27 July 2008). "Atypical Drugs of Abuse". Articles & Interviews. Student Doctor Network. Archived from the original on 27 May 2013.
Halpert AG, Olmstead MC, Beninger RJ (January 2002). "Mechanisms and abuse liability of the anti-histamine dimenhydrinate" (PDF). Neuroscience and Biobehavioral Reviews. 26 (1): 61–7. doi:10.1016/s0149-7634(01)00038-0. PMID 11835984. S2CID 46619422. Archived from the original (PDF) on 2 August 2020. Retrieved 23 December 2017.
"TikTok Videos Encourage Viewers to Overdose on Benadryl". TikTok Videos Encourage Viewers to Overdose on Benadryl. Archived from the original on 8 October 2020. Retrieved 9 October 2020.
"Dangerous 'Benadryl Challenge' on Tik Tok may be to blame for the death of Oklahoma teen". KFOR.com Oklahoma City. 28 August 2020. Archived from the original on 2 August 2021. Retrieved 9 October 2020.
"Teen's Death Prompts Warning on 'Benadryl Challenge'". medpagetoday.com. 25 September 2020. Archived from the original on 29 September 2020. Retrieved 9 October 2020.

Diphenhydramine (English Wikipedia)

aafp.org

aahpm.org

accessmedicine.com

adage.com

archive.org

bbc.com

bizjournals.com

books.google.com

checkupnewsroom.com

chestnet.org

journal.publications.chestnet.org

clincalc.com

currentpsychiatry.com

stg.currentpsychiatry.com

doi.org

drugbank.ca

drugs.com

fda.gov

gctrips.org

ghostarchive.org

handle.net

hdl.handle.net

harvard.edu

ui.adsabs.harvard.edu

independent.co.uk

kfor.com

medicines.org.uk

medlineplus.gov

medpagetoday.com

medscape.com

emedicine.medscape.com

newspapers.com

nih.gov

pubmed.ncbi.nlm.nih.gov

ncbi.nlm.nih.gov

pubchem.ncbi.nlm.nih.gov

dailymed.nlm.nih.gov

ninds.nih.gov

nlm.nih.gov

nytimes.com

ohiohistorycentral.org

queensu.ca

seattlechildrens.org

seattlemamadoc.seattlechildrens.org

semanticscholar.org

api.semanticscholar.org

state.gov

travel.state.gov

studentdoctor.net

telegraph.co.uk

unc.edu

pdsp.unc.edu

web.archive.org