ERN1 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "ERN1" in English language version.

Last modified: 10:53:54, 11 August 2026 (UTC)

Ref.Un. Ref.Website

Global rank English rank

3231nih.gov

5^th place

1616doi.org

2^nd place

62ensembl.org

630^th place

326^th place

33semanticscholar.org

15^th place

8^th place

22hdl.handle.net

66^th place

34^th place

11adsabs.harvard.edu

14^th place

9^th place

adsabs.harvard.edu (Global: 14^th place; English: 9^th place)

ui.adsabs.harvard.edu

Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP, et al. (January 2002). "IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA". Nature. 415 (6867): 92–96. Bibcode:2002Natur.415...92C. doi:10.1038/415092a. PMID 11780124. S2CID 4319118.

doi.org (Global: 2^nd place; English: 2^nd place)

Tirasophon W, Welihinda AA, Kaufman RJ (June 1998). "A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells". Genes & Development. 12 (12): 1812–1824. doi:10.1101/gad.12.12.1812. PMC 316900. PMID 9637683.
Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP, et al. (January 2002). "IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA". Nature. 415 (6867): 92–96. Bibcode:2002Natur.415...92C. doi:10.1038/415092a. PMID 11780124. S2CID 4319118.
Kurtishi A, Rosen B, Patil KS, Alves GW, Møller SG (May 2019). "Cellular Proteostasis in Neurodegeneration". Molecular Neurobiology. 56 (5): 3676–3689. doi:10.1007/s12035-018-1334-z. PMID 30182337. S2CID 52158118.
Duran-Aniotz C, Cornejo VH, Espinoza S, Ardiles ÁO, Medinas DB, Salazar C, et al. (September 2017). "IRE1 signaling exacerbates Alzheimer's disease pathogenesis". Acta Neuropathologica. 134 (3): 489–506. doi:10.1007/s00401-017-1694-x. hdl:10533/240207. PMID 28341998. S2CID 9380354.
Yan C, Liu J, Gao J, Sun Y, Zhang L, Song H, et al. (October 2019). "IRE1 promotes neurodegeneration through autophagy-dependent neuron death in the Drosophila model of Parkinson's disease". Cell Death & Disease. 10 (11) 800. doi:10.1038/s41419-019-2039-6. PMC 6805898. PMID 31641108.
Montibeller L, de Belleroche J (September 2018). "Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes". Cell Stress & Chaperones. 23 (5): 897–912. doi:10.1007/s12192-018-0897-y. PMC 6111088. PMID 29725981.
Chen D, Wang Y, Chin ER (2015-05-18). "Activation of the endoplasmic reticulum stress response in skeletal muscle of G93A*SOD1 amyotrophic lateral sclerosis mice". Frontiers in Cellular Neuroscience. 9 170. doi:10.3389/fncel.2015.00170. PMC 4435075. PMID 26041991.
Marcu MG, Doyle M, Bertolotti A, Ron D, Hendershot L, Neckers L (December 2002). "Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha". Molecular and Cellular Biology. 22 (24): 8506–8513. doi:10.1128/MCB.22.24.8506-8513.2002. PMC 139892. PMID 12446770.
Volkmann K, Lucas JL, Vuga D, Wang X, Brumm D, Stiles C, et al. (April 2011). "Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease". The Journal of Biological Chemistry. 286 (14): 12743–12755. doi:10.1074/jbc.M110.199737. PMC 3069474. PMID 21303903.
Cross BC, Bond PJ, Sadowski PG, Jha BK, Zak J, Goodman JM, et al. (April 2012). "The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule". Proceedings of the National Academy of Sciences of the United States of America. 109 (15): E869–E878. doi:10.1073/pnas.1115623109. PMC 3326519. PMID 22315414.
Mimura N, Fulciniti M, Gorgun G, Tai YT, Cirstea D, Santo L, et al. (June 2012). "Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma". Blood. 119 (24): 5772–5781. doi:10.1182/blood-2011-07-366633. PMC 3382937. PMID 22538852.
Papandreou I, Denko NC, Olson M, Van Melckebeke H, Lust S, Tam A, et al. (January 2011). "Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma". Blood. 117 (4): 1311–1314. doi:10.1182/blood-2010-08-303099. PMC 3056474. PMID 21081713.
Ri M, Tashiro E, Oikawa D, Shinjo S, Tokuda M, Yokouchi Y, et al. (July 2012). "Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing". Blood Cancer Journal. 2 (7): e79. doi:10.1038/bcj.2012.26. PMC 3408640. PMID 22852048.
Wang L, Perera BG, Hari SB, Bhhatarai B, Backes BJ, Seeliger MA, et al. (December 2012). "Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors". Nature Chemical Biology. 8 (12): 982–989. doi:10.1038/nchembio.1094. PMC 3508346. PMID 23086298.
Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, et al. (August 2018). "IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A". Nature Cell Biology. 20 (8): 942–953. doi:10.1038/s41556-018-0141-0. hdl:10533/227972. PMID 30013108.
Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, et al. (June 2024). "Protein translation rate determines neocortical neuron fate". Nature Communications. 15 (1) 4879. doi:10.1038/s41467-024-49198-w. PMC 11161512. PMID 38849354.

ensembl.org (Global: 630^th place; English: 326^th place)

may2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000178607 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000020715 – Ensembl, May 2017

hdl.handle.net (Global: 66^th place; English: 34^th place)

Duran-Aniotz C, Cornejo VH, Espinoza S, Ardiles ÁO, Medinas DB, Salazar C, et al. (September 2017). "IRE1 signaling exacerbates Alzheimer's disease pathogenesis". Acta Neuropathologica. 134 (3): 489–506. doi:10.1007/s00401-017-1694-x. hdl:10533/240207. PMID 28341998. S2CID 9380354.
Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, et al. (August 2018). "IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A". Nature Cell Biology. 20 (8): 942–953. doi:10.1038/s41556-018-0141-0. hdl:10533/227972. PMID 30013108.

nih.gov (Global: 5^th place; English: 5^th place)

pubmed.ncbi.nlm.nih.gov

Tirasophon W, Welihinda AA, Kaufman RJ (June 1998). "A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells". Genes & Development. 12 (12): 1812–1824. doi:10.1101/gad.12.12.1812. PMC 316900. PMID 9637683.
Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP, et al. (January 2002). "IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA". Nature. 415 (6867): 92–96. Bibcode:2002Natur.415...92C. doi:10.1038/415092a. PMID 11780124. S2CID 4319118.
Kurtishi A, Rosen B, Patil KS, Alves GW, Møller SG (May 2019). "Cellular Proteostasis in Neurodegeneration". Molecular Neurobiology. 56 (5): 3676–3689. doi:10.1007/s12035-018-1334-z. PMID 30182337. S2CID 52158118.
Duran-Aniotz C, Cornejo VH, Espinoza S, Ardiles ÁO, Medinas DB, Salazar C, et al. (September 2017). "IRE1 signaling exacerbates Alzheimer's disease pathogenesis". Acta Neuropathologica. 134 (3): 489–506. doi:10.1007/s00401-017-1694-x. hdl:10533/240207. PMID 28341998. S2CID 9380354.
Yan C, Liu J, Gao J, Sun Y, Zhang L, Song H, et al. (October 2019). "IRE1 promotes neurodegeneration through autophagy-dependent neuron death in the Drosophila model of Parkinson's disease". Cell Death & Disease. 10 (11) 800. doi:10.1038/s41419-019-2039-6. PMC 6805898. PMID 31641108.
Montibeller L, de Belleroche J (September 2018). "Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes". Cell Stress & Chaperones. 23 (5): 897–912. doi:10.1007/s12192-018-0897-y. PMC 6111088. PMID 29725981.
Chen D, Wang Y, Chin ER (2015-05-18). "Activation of the endoplasmic reticulum stress response in skeletal muscle of G93A*SOD1 amyotrophic lateral sclerosis mice". Frontiers in Cellular Neuroscience. 9 170. doi:10.3389/fncel.2015.00170. PMC 4435075. PMID 26041991.
Marcu MG, Doyle M, Bertolotti A, Ron D, Hendershot L, Neckers L (December 2002). "Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha". Molecular and Cellular Biology. 22 (24): 8506–8513. doi:10.1128/MCB.22.24.8506-8513.2002. PMC 139892. PMID 12446770.
Volkmann K, Lucas JL, Vuga D, Wang X, Brumm D, Stiles C, et al. (April 2011). "Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease". The Journal of Biological Chemistry. 286 (14): 12743–12755. doi:10.1074/jbc.M110.199737. PMC 3069474. PMID 21303903.
Cross BC, Bond PJ, Sadowski PG, Jha BK, Zak J, Goodman JM, et al. (April 2012). "The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule". Proceedings of the National Academy of Sciences of the United States of America. 109 (15): E869–E878. doi:10.1073/pnas.1115623109. PMC 3326519. PMID 22315414.
Mimura N, Fulciniti M, Gorgun G, Tai YT, Cirstea D, Santo L, et al. (June 2012). "Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma". Blood. 119 (24): 5772–5781. doi:10.1182/blood-2011-07-366633. PMC 3382937. PMID 22538852.
Papandreou I, Denko NC, Olson M, Van Melckebeke H, Lust S, Tam A, et al. (January 2011). "Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma". Blood. 117 (4): 1311–1314. doi:10.1182/blood-2010-08-303099. PMC 3056474. PMID 21081713.
Ri M, Tashiro E, Oikawa D, Shinjo S, Tokuda M, Yokouchi Y, et al. (July 2012). "Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing". Blood Cancer Journal. 2 (7): e79. doi:10.1038/bcj.2012.26. PMC 3408640. PMID 22852048.
Wang L, Perera BG, Hari SB, Bhhatarai B, Backes BJ, Seeliger MA, et al. (December 2012). "Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors". Nature Chemical Biology. 8 (12): 982–989. doi:10.1038/nchembio.1094. PMC 3508346. PMID 23086298.
Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, et al. (August 2018). "IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A". Nature Cell Biology. 20 (8): 942–953. doi:10.1038/s41556-018-0141-0. hdl:10533/227972. PMID 30013108.
Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, et al. (June 2024). "Protein translation rate determines neocortical neuron fate". Nature Communications. 15 (1) 4879. doi:10.1038/s41467-024-49198-w. PMC 11161512. PMID 38849354.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Tirasophon W, Welihinda AA, Kaufman RJ (June 1998). "A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells". Genes & Development. 12 (12): 1812–1824. doi:10.1101/gad.12.12.1812. PMC 316900. PMID 9637683.
"Entrez Gene: ERN1 endoplasmic reticulum to nucleus signalling 1".
Yan C, Liu J, Gao J, Sun Y, Zhang L, Song H, et al. (October 2019). "IRE1 promotes neurodegeneration through autophagy-dependent neuron death in the Drosophila model of Parkinson's disease". Cell Death & Disease. 10 (11) 800. doi:10.1038/s41419-019-2039-6. PMC 6805898. PMID 31641108.
Montibeller L, de Belleroche J (September 2018). "Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes". Cell Stress & Chaperones. 23 (5): 897–912. doi:10.1007/s12192-018-0897-y. PMC 6111088. PMID 29725981.
Chen D, Wang Y, Chin ER (2015-05-18). "Activation of the endoplasmic reticulum stress response in skeletal muscle of G93A*SOD1 amyotrophic lateral sclerosis mice". Frontiers in Cellular Neuroscience. 9 170. doi:10.3389/fncel.2015.00170. PMC 4435075. PMID 26041991.
Marcu MG, Doyle M, Bertolotti A, Ron D, Hendershot L, Neckers L (December 2002). "Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha". Molecular and Cellular Biology. 22 (24): 8506–8513. doi:10.1128/MCB.22.24.8506-8513.2002. PMC 139892. PMID 12446770.
Volkmann K, Lucas JL, Vuga D, Wang X, Brumm D, Stiles C, et al. (April 2011). "Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease". The Journal of Biological Chemistry. 286 (14): 12743–12755. doi:10.1074/jbc.M110.199737. PMC 3069474. PMID 21303903.
Cross BC, Bond PJ, Sadowski PG, Jha BK, Zak J, Goodman JM, et al. (April 2012). "The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule". Proceedings of the National Academy of Sciences of the United States of America. 109 (15): E869–E878. doi:10.1073/pnas.1115623109. PMC 3326519. PMID 22315414.
Mimura N, Fulciniti M, Gorgun G, Tai YT, Cirstea D, Santo L, et al. (June 2012). "Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma". Blood. 119 (24): 5772–5781. doi:10.1182/blood-2011-07-366633. PMC 3382937. PMID 22538852.
Papandreou I, Denko NC, Olson M, Van Melckebeke H, Lust S, Tam A, et al. (January 2011). "Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma". Blood. 117 (4): 1311–1314. doi:10.1182/blood-2010-08-303099. PMC 3056474. PMID 21081713.
Ri M, Tashiro E, Oikawa D, Shinjo S, Tokuda M, Yokouchi Y, et al. (July 2012). "Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing". Blood Cancer Journal. 2 (7): e79. doi:10.1038/bcj.2012.26. PMC 3408640. PMID 22852048.
Wang L, Perera BG, Hari SB, Bhhatarai B, Backes BJ, Seeliger MA, et al. (December 2012). "Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors". Nature Chemical Biology. 8 (12): 982–989. doi:10.1038/nchembio.1094. PMC 3508346. PMID 23086298.
Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, et al. (June 2024). "Protein translation rate determines neocortical neuron fate". Nature Communications. 15 (1) 4879. doi:10.1038/s41467-024-49198-w. PMC 11161512. PMID 38849354.

semanticscholar.org (Global: 15^th place; English: 8^th place)

api.semanticscholar.org

Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP, et al. (January 2002). "IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA". Nature. 415 (6867): 92–96. Bibcode:2002Natur.415...92C. doi:10.1038/415092a. PMID 11780124. S2CID 4319118.
Kurtishi A, Rosen B, Patil KS, Alves GW, Møller SG (May 2019). "Cellular Proteostasis in Neurodegeneration". Molecular Neurobiology. 56 (5): 3676–3689. doi:10.1007/s12035-018-1334-z. PMID 30182337. S2CID 52158118.
Duran-Aniotz C, Cornejo VH, Espinoza S, Ardiles ÁO, Medinas DB, Salazar C, et al. (September 2017). "IRE1 signaling exacerbates Alzheimer's disease pathogenesis". Acta Neuropathologica. 134 (3): 489–506. doi:10.1007/s00401-017-1694-x. hdl:10533/240207. PMID 28341998. S2CID 9380354.

ERN1 (English Wikipedia)

adsabs.harvard.edu (Global: 14th place; English: 9th place)

ui.adsabs.harvard.edu

doi.org (Global: 2nd place; English: 2nd place)

ensembl.org (Global: 630th place; English: 326th place)