Epigenetics of anxiety and stress–related disorders (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Epigenetics of anxiety and stress–related disorders" in English language version.

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159nih.gov

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alcohol.org

"Alcohol Addiction and Co-Occurring Disorders - Dual Diagnosis". Alcohol.org. Retrieved 2024-04-14.

alcoholrehabguide.org

"Dual Diagnosis". Alcohol Rehab Guide. Retrieved 2024-04-14.

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Matthews SG, Phillips DI (January 2012). "Transgenerational inheritance of stress pathology". review. Experimental Neurology. 233 (1): 95–101. doi:10.1016/j.expneurol.2011.01.009. PMID 21281632. S2CID 30261742.
Klengel T, Binder EB (June 2015). "Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions". review. Neuron. 86 (6): 1343–1357. doi:10.1016/j.neuron.2015.05.036. PMID 26087162.
Gudsnuk K, Champagne FA (2012). "Epigenetic influence of stress and the social environment". review. ILAR Journal. 53 (3–4): 279–288. doi:10.1093/ilar.53.3-4.279. PMC 4021821. PMID 23744967.
Vialou V, Feng J, Robison AJ, Nestler EJ (2013). "Epigenetic mechanisms of depression and antidepressant action". review. Annual Review of Pharmacology and Toxicology. 53: 59–87. doi:10.1146/annurev-pharmtox-010611-134540. PMC 3711377. PMID 23020296.
Szyf M, Weaver I, Meaney M (July 2007). "Maternal care, the epigenome and phenotypic differences in behavior". review. Reproductive Toxicology. 24 (1): 9–19. doi:10.1016/j.reprotox.2007.05.001. PMID 17561370.
Daskalakis NP, Cohen H, Nievergelt CM, Baker DG, Buxbaum JD, Russo SJ, et al. (October 2016). "New translational perspectives for blood-based biomarkers of PTSD: From glucocorticoid to immune mediators of stress susceptibility". review. Experimental Neurology. 284 (Pt B): 133–140. doi:10.1016/j.expneurol.2016.07.024. PMC 5056828. PMID 27481726.
Kim M, Costello J (April 2017). "DNA methylation: an epigenetic mark of cellular memory". Experimental & Molecular Medicine. 49 (4): e322. doi:10.1038/emm.2017.10. PMC 6130213. PMID 28450738.
Bellini E, Pavesi G, Barbiero I, Bergo A, Chandola C, Nawaz MS, et al. (2014). "MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?". review. Frontiers in Cellular Neuroscience. 8: 236. doi:10.3389/fncel.2014.00236. PMC 4131190. PMID 25165434.
Lee RS, Tamashiro KL, Yang X, Purcell RH, Huo Y, Rongione M, et al. (November 2011). "A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice". primary. Psychopharmacology. 218 (1): 303–312. doi:10.1007/s00213-011-2307-3. PMC 3918452. PMID 21509501.
Sipahi L, Wildman DE, Aiello AE, Koenen KC, Galea S, Abbas A, et al. (November 2014). "Longitudinal epigenetic variation of DNA methyltransferase genes is associated with vulnerability to post-traumatic stress disorder". primary. Psychological Medicine. 44 (15): 3165–3179. doi:10.1017/S0033291714000968. PMC 4530981. PMID 25065861.
Weaver IC, Cervoni N, Champagne FA, D'Alessio AC, Sharma S, Seckl JR, et al. (August 2004). "Epigenetic programming by maternal behavior". primary. Nature Neuroscience. 7 (8): 847–854. doi:10.1038/nn1276. PMID 15220929. S2CID 1649281.
Zhang TY, Labonté B, Wen XL, Turecki G, Meaney MJ (January 2013). "Epigenetic mechanisms for the early environmental regulation of hippocampal glucocorticoid receptor gene expression in rodents and humans". review. Neuropsychopharmacology. 38 (1): 111–123. doi:10.1038/npp.2012.149. PMC 3521971. PMID 22968814.
Levine A, Worrell TR, Zimnisky R, Schmauss C (January 2012). "Early life stress triggers sustained changes in histone deacetylase expression and histone H4 modifications that alter responsiveness to adolescent antidepressant treatment". primary. Neurobiology of Disease. 45 (1): 488–498. doi:10.1016/j.nbd.2011.09.005. PMC 3225638. PMID 21964251.
Tesone-Coelho C, Morel LJ, Bhatt J, Estevez L, Naudon L, Giros B, et al. (January 2015). "Vulnerability to opiate intake in maternally deprived rats: implication of MeCP2 and of histone acetylation". primary. Addiction Biology. 20 (1): 120–131. doi:10.1111/adb.12084. PMID 23980619. S2CID 5938827.
Suri D, Bhattacharya A, Vaidya VA (February 2014). "Early stress evokes temporally distinct consequences on the hippocampal transcriptome, anxiety and cognitive behaviour". primary. The International Journal of Neuropsychopharmacology. 17 (2): 289–301. doi:10.1017/S1461145713001004. PMID 24025219.
Smeeth D, Beck S, Karam EG, Pluess M (July 2021). "The role of epigenetics in psychological resilience". The Lancet Psychiatry. 8 (7): 620–629. doi:10.1016/S2215-0366(20)30515-0. PMC 9561637. PMID 33915083.
Jawaid A, Roszkowski M, Mansuy IM (2018). "Transgenerational Epigenetics of Traumatic Stress". Progress in Molecular Biology and Translational Science. 158. Elsevier: 273–298. doi:10.1016/bs.pmbts.2018.03.003. ISBN 978-0-12-812592-2. PMID 30072057.
Wang F, Pan F, Tang Y, Huang JH (2021). "Editorial: Early Life Stress-Induced Epigenetic Changes Involved in Mental Disorders". Frontiers in Genetics. 12: 684844. doi:10.3389/fgene.2021.684844. PMC 8320347. PMID 34335692.
Grezenko H, Ekhator C, Nwabugwu NU, Ganga H, Affaf M, Abdelaziz AM, et al. (August 2023). "Epigenetics in Neurological and Psychiatric Disorders: A Comprehensive Review of Current Understanding and Future Perspectives". Cureus. 15 (8): e43960. doi:10.7759/cureus.43960. PMC 10446850. PMID 37622055.
Yeshurun S, Hannan AJ (April 2019). "Transgenerational epigenetic influences of paternal environmental exposures on brain function and predisposition to psychiatric disorders". review. Molecular Psychiatry. 24 (4): 536–548. doi:10.1038/s41380-018-0039-z. PMID 29520039. S2CID 3767345.
Yahyavi ST, Zarghami M, Marwah U (2013). "A review on the evidence of transgenerational transmission of posttraumatic stress disorder vulnerability". review. Revista Brasileira de Psiquiatria. 36 (1): 89–94. doi:10.1590/1516-4446-2012-0995. PMID 24402183.
Li SC (November 2013). "Neuromodulation and developmental contextual influences on neural and cognitive plasticity across the lifespan". review. Neuroscience and Biobehavioral Reviews. 37 (9 Pt B): 2201–2208. doi:10.1016/j.neubiorev.2013.07.019. PMID 23973556. S2CID 46501356.
Hodes GE, Walker DM, Labonté B, Nestler EJ, Russo SJ (January 2017). "Understanding the epigenetic basis of sex differences in depression". review. Journal of Neuroscience Research. 95 (1–2): 692–702. doi:10.1002/jnr.23876. PMC 5130105. PMID 27870456.
Duncan EJ, Gluckman PD, Dearden PK (June 2014). "Epigenetics, plasticity, and evolution: How do we link epigenetic change to phenotype?". Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution. 322 (4): 208–220. doi:10.1002/jez.b.22571. ISSN 1552-5015. PMID 24719220.
Yehuda R, Halligan SL, Bierer LM (2001). "Relationship of parental trauma exposure and PTSD to PTSD, depressive and anxiety disorders in offspring". primary. Journal of Psychiatric Research. 35 (5): 261–270. doi:10.1016/S0022-3956(01)00032-2. PMID 11591428.
Yehuda R, Bierer LM (2008). "Transgenerational transmission of cortisol and PTSD risk". Stress Hormones and Post Traumatic Stress Disorder Basic Studies and Clinical Perspectives. review. Progress in Brain Research. Vol. 167. pp. 121–35. doi:10.1016/S0079-6123(07)67009-5. ISBN 978-0-444-53140-7. PMID 18037011.
Yehuda R, Daskalakis NP, Lehrner A, Desarnaud F, Bader HN, Makotkine I, et al. (August 2014). "Influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in Holocaust survivor offspring". primary. The American Journal of Psychiatry. 171 (8): 872–880. doi:10.1176/appi.ajp.2014.13121571. PMC 4127390. PMID 24832930.
Bierer LM, Bader HN, Daskalakis NP, Lehrner A, Provençal N, Wiechmann T, et al. (August 2020). "Intergenerational Effects of Maternal Holocaust Exposure on FKBP5 Methylation". The American Journal of Psychiatry. 177 (8): 744–753. doi:10.1176/appi.ajp.2019.19060618. PMID 32312110.
Kellermann NP (August 2001). "Transmission of Holocaust trauma--an integrative view". Psychiatry. 64 (3): 256–267. doi:10.1521/psyc.64.3.256.18464. PMID 11708051.
Franklin TB, Russig H, Weiss IC, Gräff J, Linder N, Michalon A, et al. (September 2010). "Epigenetic transmission of the impact of early stress across generations". primary. Biological Psychiatry. 68 (5): 408–415. doi:10.1016/j.biopsych.2010.05.036. PMID 20673872. S2CID 15851484.
Yuan TF, Li A, Sun X, Ouyang H, Campos C, Rocha NB, et al. (November 2016). "Transgenerational Inheritance of Paternal Neurobehavioral Phenotypes: Stress, Addiction, Ageing and Metabolism". review. Molecular Neurobiology. 53 (9): 6367–6376. doi:10.1007/s12035-015-9526-2. hdl:10400.22/7331. PMID 26572641. S2CID 25694221.
Gapp K, Jawaid A, Sarkies P, Bohacek J, Pelczar P, Prados J, et al. (May 2014). "Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice". primary. Nature Neuroscience. 17 (5): 667–669. doi:10.1038/nn.3695. PMC 4333222. PMID 24728267.
Sharma U, Rando OJ (June 2014). "Father-son chats: inheriting stress through sperm RNA". comment. Cell Metabolism. 19 (6): 894–895. doi:10.1016/j.cmet.2014.05.015. PMC 4131544. PMID 24896534.
Short AK, Yeshurun S, Powell R, Perreau VM, Fox A, Kim JH, et al. (May 2017). "Exercise alters mouse sperm small noncoding RNAs and induces a transgenerational modification of male offspring conditioned fear and anxiety". primary. Translational Psychiatry. 7 (5): e1114. doi:10.1038/tp.2017.82. PMC 5534950. PMID 28463242.
Zschucke E, Renneberg B, Dimeo F, Wüstenberg T, Ströhle A (January 2015). "The stress-buffering effect of acute exercise: Evidence for HPA axis negative feedback". Psychoneuroendocrinology. This issue includes a Special Section on Biomarkers in the Military - New Findings from Prospective Studies. 51: 414–425. doi:10.1016/j.psyneuen.2014.10.019. PMID 25462913.
Gapp K, Bohacek J, Grossmann J, Brunner AM, Manuella F, Nanni P, et al. (October 2016). "Potential of Environmental Enrichment to Prevent Transgenerational Effects of Paternal Trauma". primary. Neuropsychopharmacology. 41 (11): 2749–2758. doi:10.1038/npp.2016.87. PMC 5026744. PMID 27277118.
Mitchell C, Schneper LM, Notterman DA (January 2016). "DNA methylation, early life environment, and health outcomes". review. Pediatric Research. 79 (1–2): 212–219. doi:10.1038/pr.2015.193. PMC 4798238. PMID 26466079.
Johnstone SE, Baylin SB (November 2010). "Stress and the epigenetic landscape: a link to the pathobiology of human diseases?". Nature Reviews. Genetics. 11 (11): 806–812. doi:10.1038/nrg2881. PMC 3148009. PMID 20921961.
Jiang S, Postovit L, Cattaneo A, Binder EB, Aitchison KJ (2019). "Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma". Frontiers in Psychiatry. 10: 808. doi:10.3389/fpsyt.2019.00808. PMC 6857662. PMID 31780969.
Daskalakis NP, Cohen H, Nievergelt CM, Baker DG, Buxbaum JD, Russo SJ, et al. (October 2016). "New translational perspectives for blood-based biomarkers of PTSD: From glucocorticoid to immune mediators of stress susceptibility". Experimental Neurology. Special Issue: New Perspectives in PTSD. 284 (Pt B): 133–140. doi:10.1016/j.expneurol.2016.07.024. PMC 5056828. PMID 27481726.
Katrinli S, Zheng Y, Gautam A, Hammamieh R, Yang R, Venkateswaran S, et al. (January 2021). "PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L". Brain, Behavior, and Immunity. 91: 429–436. doi:10.1016/j.bbi.2020.10.023. PMC 7749859. PMID 33152445.
Zhang Y, Zhao G, Han Y, Zhang J, Cao C, Wang L, et al. (2022). "The mechanisms of histone modification in post-traumatic stress disorder". Advances in Psychological Science. 30 (1): 98–114. doi:10.3724/SP.J.1042.2022.00098. ISSN 1671-3710.
Liddell BJ, Jobson L (2016-06-13). "The impact of cultural differences in self-representation on the neural substrates of posttraumatic stress disorder". European Journal of Psychotraumatology. 7 (1). doi:10.3402/ejpt.v7.30464. ISSN 2000-8066. PMC 4908066. Archived from the original on 2025-02-03.
Greer CB, Wright J, Weiss JD, Lazarenko RM, Moran SP, Zhu J, et al. (January 2021). "Tet1 Isoforms Differentially Regulate Gene Expression, Synaptic Transmission, and Memory in the Mammalian Brain". The Journal of Neuroscience. 41 (4): 578–593. doi:10.1523/JNEUROSCI.1821-20.2020. PMC 7842754. PMID 33262245.
Zannas AS, Provençal N, Binder EB (September 2015). "Epigenetics of Posttraumatic Stress Disorder: Current Evidence, Challenges, and Future Directions". review. Biological Psychiatry. 78 (5): 327–335. doi:10.1016/j.biopsych.2015.04.003. PMID 25979620. S2CID 20876167.
Koenen KC, Uddin M, Chang SC, Aiello AE, Wildman DE, Goldmann E, et al. (August 2011). "SLC6A4 methylation modifies the effect of the number of traumatic events on risk for posttraumatic stress disorder". review. Depression and Anxiety. 28 (8): 639–647. doi:10.1002/da.20825. PMC 3145829. PMID 21608084.
Uddin M, Galea S, Chang SC, Aiello AE, Wildman DE, de los Santos R, et al. (2011). "Gene expression and methylation signatures of MAN2C1 are associated with PTSD". primary. Disease Markers. 30 (2–3): 111–121. doi:10.1155/2011/513659. PMC 3188659. PMID 21508515.
Smith AK, Conneely KN, Kilaru V, Mercer KB, Weiss TE, Bradley B, et al. (September 2011). "Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder". primary. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 156B (6): 700–708. doi:10.1002/ajmg.b.31212. PMC 3292872. PMID 21714072.
Ressler KJ, Mercer KB, Bradley B, Jovanovic T, Mahan A, Kerley K, et al. (February 2011). "Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor". primary. Nature. 470 (7335): 492–497. Bibcode:2011Natur.470..492R. doi:10.1038/nature09856. PMC 3046811. PMID 21350482.
Rusiecki JA, Chen L, Srikantan V, Zhang L, Yan L, Polin ML, et al. (February 2012). "DNA methylation in repetitive elements and post-traumatic stress disorder: a case-control study of US military service members". primary. Epigenomics. 4 (1): 29–40. doi:10.2217/epi.11.116. PMC 3809831. PMID 22332656.
Chang SC, Koenen KC, Galea S, Aiello AE, Soliven R, Wildman DE, et al. (2012). "Molecular variation at the SLC6A3 locus predicts lifetime risk of PTSD in the Detroit Neighborhood Health Study". primary. PLOS ONE. 7 (6): e39184. Bibcode:2012PLoSO...739184C. doi:10.1371/journal.pone.0039184. PMC 3383758. PMID 22745713.
Rusiecki JA, Byrne C, Galdzicki Z, Srikantan V, Chen L, Poulin M, et al. (2013). "PTSD and DNA Methylation in Select Immune Function Gene Promoter Regions: A Repeated Measures Case-Control Study of U.S. Military Service Members". primary. Frontiers in Psychiatry. 4: 56. doi:10.3389/fpsyt.2013.00056. PMC 3690381. PMID 23805108.
Labonté B, Azoulay N, Yerko V, Turecki G, Brunet A (March 2014). "Epigenetic modulation of glucocorticoid receptors in posttraumatic stress disorder". primary. Translational Psychiatry. 4 (3): e368. doi:10.1038/tp.2014.3. PMC 3966043. PMID 24594779.
Yehuda R, Flory JD, Bierer LM, Henn-Haase C, Lehrner A, Desarnaud F, et al. (February 2015). "Lower methylation of glucocorticoid receptor gene promoter 1F in peripheral blood of veterans with posttraumatic stress disorder". primary. Biological Psychiatry. 77 (4): 356–364. doi:10.1016/j.biopsych.2014.02.006. PMID 24661442. S2CID 38006995.
Vukojevic V, Kolassa IT, Fastenrath M, Gschwind L, Spalek K, Milnik A, et al. (July 2014). "Epigenetic modification of the glucocorticoid receptor gene is linked to traumatic memory and post-traumatic stress disorder risk in genocide survivors". primary. The Journal of Neuroscience. 34 (31): 10274–10284. doi:10.1523/JNEUROSCI.1526-14.2014. PMC 6608273. PMID 25080589.
Blacker CJ, Frye MA, Morava E, Kozicz T, Veldic M (February 2019). "A Review of Epigenetics of PTSD in Comorbid Psychiatric Conditions". Genes. 10 (2): 140. doi:10.3390/genes10020140. PMC 6410143. PMID 30781888.
Dunlop BW, Wong A (March 2019). "The hypothalamic-pituitary-adrenal axis in PTSD: Pathophysiology and treatment interventions". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 89: 361–379. doi:10.1016/j.pnpbp.2018.10.010. PMID 30342071. S2CID 53044044.
Uddin M, Aiello AE, Wildman DE, Koenen KC, Pawelec G, de Los Santos R, et al. (May 2010). "Epigenetic and immune function profiles associated with posttraumatic stress disorder". primary. Proceedings of the National Academy of Sciences of the United States of America. 107 (20): 9470–9475. Bibcode:2010PNAS..107.9470U. doi:10.1073/pnas.0910794107. PMC 2889041. PMID 20439746.
Blouin AM, Sillivan SE, Joseph NF, Miller CA (October 2016). "The potential of epigenetics in stress-enhanced fear learning models of PTSD". Learning & Memory. 23 (10): 576–586. doi:10.1101/lm.040485.115. PMC 5026205. PMID 27634148.
Yehuda R, Daskalakis NP, Desarnaud F, Makotkine I, Lehrner AL, Koch E, et al. (2013). "Epigenetic Biomarkers as Predictors and Correlates of Symptom Improvement Following Psychotherapy in Combat Veterans with PTSD". primary. Frontiers in Psychiatry. 4: 118. doi:10.3389/fpsyt.2013.00118. PMC 3784793. PMID 24098286.
Zannas AS, Binder EB (January 2014). "Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism". review. Genes, Brain and Behavior. 13 (1): 25–37. doi:10.1111/gbb.12104. PMID 24219237. S2CID 41781060.
Zhang X, Clark AF, Yorio T (March 2008). "FK506-binding protein 51 regulates nuclear transport of the glucocorticoid receptor beta and glucocorticoid responsiveness". Investigative Ophthalmology & Visual Science. 49 (3): 1037–1047. doi:10.1167/iovs.07-1279. PMC 2442563. PMID 18326728.
Wochnik GM, Rüegg J, Abel GA, Schmidt U, Holsboer F, Rein T (February 2005). "FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells". primary. The Journal of Biological Chemistry. 280 (6): 4609–4616. doi:10.1074/jbc.M407498200. PMID 15591061.
Xie P, Kranzler HR, Poling J, Stein MB, Anton RF, Farrer LA, et al. (July 2010). "Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder". primary. Neuropsychopharmacology. 35 (8): 1684–1692. doi:10.1038/npp.2010.37. PMC 2946626. PMID 20393453.
Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, Mercer KB, et al. (March 2008). "Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults". primary. JAMA. 299 (11): 1291–1305. doi:10.1001/jama.299.11.1291. PMC 2441757. PMID 18349090.
Boscarino JA, Erlich PM, Hoffman SN, Zhang X (2012). "Higher FKBP5, COMT, CHRNA5, and CRHR1 allele burdens are associated with PTSD and interact with trauma exposure: implications for neuropsychiatric research and treatment". primary. Neuropsychiatric Disease and Treatment. 8: 131–139. doi:10.2147/NDT.S29508. PMC 3333786. PMID 22536069.
Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, et al. (January 2013). "Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions". primary. Nature Neuroscience. 16 (1): 33–41. doi:10.1038/nn.3275. PMC 4136922. PMID 23201972.
Longley MJ, Lee J, Jung J, Lohoff FW (November 2021). "Epigenetics of alcohol use disorder—A review of recent advances in DNA methylation profiling". Addiction Biology. 26 (6): e13006. doi:10.1111/adb.13006. ISSN 1355-6215. PMC 8596445. PMID 33538087.
Palmisano M, Pandey SC (May 2017). "Epigenetic mechanisms of alcoholism and stress-related disorders". review. Alcohol. 60: 7–18. doi:10.1016/j.alcohol.2017.01.001. PMC 5464725. PMID 28477725.
Agudelo M, Figueroa G, Parira T, Yndart A, Muñoz K, Atluri V, et al. (2016). "Profile of Class I Histone Deacetylases (HDAC) by Human Dendritic Cells after Alcohol Consumption and In Vitro Alcohol Treatment and Their Implication in Oxidative Stress: Role of HDAC Inhibitors Trichostatin A and Mocetinostat". primary. PLOS ONE. 11 (6): e0156421. Bibcode:2016PLoSO..1156421A. doi:10.1371/journal.pone.0156421. PMC 4889108. PMID 27249803.
Moonat S, Sakharkar AJ, Zhang H, Tang L, Pandey SC (April 2013). "Aberrant histone deacetylase2-mediated histone modifications and synaptic plasticity in the amygdala predisposes to anxiety and alcoholism". primary. Biological Psychiatry. 73 (8): 763–773. doi:10.1016/j.biopsych.2013.01.012. PMC 3718567. PMID 23485013.
Pandey SC, Ugale R, Zhang H, Tang L, Prakash A (April 2008). "Brain chromatin remodeling: a novel mechanism of alcoholism". primary. The Journal of Neuroscience. 28 (14): 3729–3737. doi:10.1523/JNEUROSCI.5731-07.2008. PMC 6671100. PMID 18385331.
Maron E, Nutt D (September 2015). "Biological predictors of pharmacological therapy in anxiety disorders". Dialogues in Clinical Neuroscience. 17 (3): 305–317. doi:10.31887/DCNS.2015.17.3/emaron. PMC 4610615. PMID 26487811.
Roy-Byrne P (June 2015). "Treatment-refractory anxiety; definition, risk factors, and treatment challenges". Dialogues in Clinical Neuroscience. 17 (2): 191–206. doi:10.31887/DCNS.2015.17.2/proybyrne. PMC 4518702. PMID 26246793.
Peedicayil J (March 2020). "The Potential Role of Epigenetic Drugs in the Treatment of Anxiety Disorders". Neuropsychiatric Disease and Treatment. 16 (16): 597–606. doi:10.2147/NDT.S242040. PMC 7060022. PMID 32184601.
Eckschlager T, Plch J, Stiborova M, Hrabeta J (July 2017). "Histone Deacetylase Inhibitors as Anticancer Drugs". International Journal of Molecular Sciences. 18 (7): 1414. doi:10.3390/ijms18071414. PMC 5535906. PMID 28671573.
Rajan A, Shi H, Xue B (August 2018). "Class I and II Histone Deacetylase Inhibitors Differentially Regulate Thermogenic Gene Expression in Brown Adipocytes". Scientific Reports. 8 (1): 13072. Bibcode:2018NatSR...813072R. doi:10.1038/s41598-018-31560-w. PMC 6117331. PMID 30166563.
Wei Y, Melas PA, Wegener G, Mathé AA, Lavebratt C (October 2014). "Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene". The International Journal of Neuropsychopharmacology. 18 (2): pyu032. doi:10.1093/ijnp/pyu032. PMC 4368891. PMID 25618518.
Primeau F, Fontaine R, Beauclair L (April 1990). "Valproic acid and panic disorder". Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie. 35 (3): 248–250. doi:10.1177/070674379003500309. PMID 2111204. S2CID 37695090.
Keck PE, Taylor VE, Tugrul KC, McElroy SL, Bennett JA (April 1993). "Valproate treatment of panic disorder and lactate-induced panic attacks". Biological Psychiatry. 33 (7): 542–546. doi:10.1016/0006-3223(93)90010-B. PMID 8513040. S2CID 1411404.
Kinrys G, Pollack MH, Simon NM, Worthington JJ, Nardi AE, Versiani M (May 2003). "Valproic acid for the treatment of social anxiety disorder". International Clinical Psychopharmacology. 18 (3): 169–172. doi:10.1097/01.yic.0000064261.66765.9f. PMID 12702897. S2CID 43035988.
Aliyev NA, Aliyev ZN (March 2008). "Valproate (depakine-chrono) in the acute treatment of outpatients with generalized anxiety disorder without psychiatric comorbidity: randomized, double-blind placebo-controlled study". European Psychiatry. 23 (2): 109–114. doi:10.1016/j.eurpsy.2007.08.001. PMID 17945470. S2CID 20266182.
Bach DR, Korn CW, Vunder J, Bantel A (August 2018). "Effect of valproate and pregabalin on human anxiety-like behaviour in a randomised controlled trial". Translational Psychiatry. 8 (1): 157. doi:10.1038/s41398-018-0206-7. PMC 6095858. PMID 30115911.
Whittle N, Schmuckermair C, Gunduz Cinar O, Hauschild M, Ferraguti F, Holmes A, et al. (January 2013). "Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model". Neuropharmacology. 64 (4): 414–423. doi:10.1016/j.neuropharm.2012.06.001. PMC 3474950. PMID 22722028.
You C, Zhang H, Sakharkar AJ, Teppen T, Pandey SC (February 2014). "Reversal of deficits in dendritic spines, BDNF and Arc expression in the amygdala during alcohol dependence by HDAC inhibitor treatment". The International Journal of Neuropsychopharmacology. 17 (2): 313–322. doi:10.1017/S1461145713001144. PMC 4093912. PMID 24103311.
Moloney RD, Stilling RM, Dinan TG, Cryan JF (December 2015). "Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition". Neurogastroenterology and Motility. 27 (12): 1831–1836. doi:10.1111/nmo.12675. PMID 26403543. S2CID 30923705.
Hayase T (July 2016). "Putative Epigenetic Involvement of the Endocannabinoid System in Anxiety- and Depression-Related Behaviors Caused by Nicotine as a Stressor". PLOS ONE. 11 (7): e0158950. Bibcode:2016PLoSO..1158950H. doi:10.1371/journal.pone.0158950. PMC 4942073. PMID 27404492.
Karnib N, El-Ghandour R, El Hayek L, Nasrallah P, Khalifeh M, Barmo N, et al. (May 2019). "Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases". Neuropsychopharmacology. 44 (6): 1152–1162. doi:10.1038/s41386-019-0313-z. PMC 6461925. PMID 30647450.
Baud O, Watterberg KL (June 2019). "Prophylactic postnatal corticosteroids: Early hydrocortisone". Seminars in Fetal & Neonatal Medicine. 24 (3): 202–206. doi:10.1016/j.siny.2019.04.007. PMID 31043325.
Kothgassner OD, Pellegrini M, Goreis A, Giordano V, Edobor J, Fischer S, et al. (April 2021). "Hydrocortisone administration for reducing post-traumatic stress symptoms: A systematic review and meta-analysis". Psychoneuroendocrinology. 126: 105168. doi:10.1016/j.psyneuen.2021.105168. PMID 33626392. S2CID 231930081.
Zohar J, Yahalom H, Kozlovsky N, Cwikel-Hamzany S, Matar MA, Kaplan Z, et al. (November 2011). "High dose hydrocortisone immediately after trauma may alter the trajectory of PTSD: interplay between clinical and animal studies". European Neuropsychopharmacology. 21 (11): 796–809. doi:10.1016/j.euroneuro.2011.06.001. PMID 21741804. S2CID 32595065.
Al Jowf GI, Snijders C, Rutten BP, de Nijs L, Eijssen LM (October 2021). "The Molecular Biology of Susceptibility to Post-Traumatic Stress Disorder: Highlights of Epigenetics and Epigenomics". International Journal of Molecular Sciences. 22 (19): 10743. doi:10.3390/ijms221910743. PMC 8509551. PMID 34639084.
Tortella-Feliu M, Fullana MA, Pérez-Vigil A, Torres X, Chamorro J, Littarelli SA, et al. (December 2019). "Risk factors for posttraumatic stress disorder: An umbrella review of systematic reviews and meta-analyses". Neuroscience and Biobehavioral Reviews. 107: 154–165. doi:10.1016/j.neubiorev.2019.09.013. PMID 31520677. S2CID 202558369.

handle.net

hdl.handle.net

Yuan TF, Li A, Sun X, Ouyang H, Campos C, Rocha NB, et al. (November 2016). "Transgenerational Inheritance of Paternal Neurobehavioral Phenotypes: Stress, Addiction, Ageing and Metabolism". review. Molecular Neurobiology. 53 (9): 6367–6376. doi:10.1007/s12035-015-9526-2. hdl:10400.22/7331. PMID 26572641. S2CID 25694221.

harvard.edu

ui.adsabs.harvard.edu

Ressler KJ, Mercer KB, Bradley B, Jovanovic T, Mahan A, Kerley K, et al. (February 2011). "Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor". primary. Nature. 470 (7335): 492–497. Bibcode:2011Natur.470..492R. doi:10.1038/nature09856. PMC 3046811. PMID 21350482.
Chang SC, Koenen KC, Galea S, Aiello AE, Soliven R, Wildman DE, et al. (2012). "Molecular variation at the SLC6A3 locus predicts lifetime risk of PTSD in the Detroit Neighborhood Health Study". primary. PLOS ONE. 7 (6): e39184. Bibcode:2012PLoSO...739184C. doi:10.1371/journal.pone.0039184. PMC 3383758. PMID 22745713.
Uddin M, Aiello AE, Wildman DE, Koenen KC, Pawelec G, de Los Santos R, et al. (May 2010). "Epigenetic and immune function profiles associated with posttraumatic stress disorder". primary. Proceedings of the National Academy of Sciences of the United States of America. 107 (20): 9470–9475. Bibcode:2010PNAS..107.9470U. doi:10.1073/pnas.0910794107. PMC 2889041. PMID 20439746.
Agudelo M, Figueroa G, Parira T, Yndart A, Muñoz K, Atluri V, et al. (2016). "Profile of Class I Histone Deacetylases (HDAC) by Human Dendritic Cells after Alcohol Consumption and In Vitro Alcohol Treatment and Their Implication in Oxidative Stress: Role of HDAC Inhibitors Trichostatin A and Mocetinostat". primary. PLOS ONE. 11 (6): e0156421. Bibcode:2016PLoSO..1156421A. doi:10.1371/journal.pone.0156421. PMC 4889108. PMID 27249803.
Rajan A, Shi H, Xue B (August 2018). "Class I and II Histone Deacetylase Inhibitors Differentially Regulate Thermogenic Gene Expression in Brown Adipocytes". Scientific Reports. 8 (1): 13072. Bibcode:2018NatSR...813072R. doi:10.1038/s41598-018-31560-w. PMC 6117331. PMID 30166563.
Hayase T (July 2016). "Putative Epigenetic Involvement of the Endocannabinoid System in Anxiety- and Depression-Related Behaviors Caused by Nicotine as a Stressor". PLOS ONE. 11 (7): e0158950. Bibcode:2016PLoSO..1158950H. doi:10.1371/journal.pone.0158950. PMC 4942073. PMID 27404492.

mit.edu

wi.mit.edu

"Whitehead Institute of MIT". Whitehead Institute of MIT. 18 September 2013. Retrieved 2022-05-20.

nih.gov

pubmed.ncbi.nlm.nih.gov

Matthews SG, Phillips DI (January 2012). "Transgenerational inheritance of stress pathology". review. Experimental Neurology. 233 (1): 95–101. doi:10.1016/j.expneurol.2011.01.009. PMID 21281632. S2CID 30261742.
Klengel T, Binder EB (June 2015). "Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions". review. Neuron. 86 (6): 1343–1357. doi:10.1016/j.neuron.2015.05.036. PMID 26087162.
Gudsnuk K, Champagne FA (2012). "Epigenetic influence of stress and the social environment". review. ILAR Journal. 53 (3–4): 279–288. doi:10.1093/ilar.53.3-4.279. PMC 4021821. PMID 23744967.
Vialou V, Feng J, Robison AJ, Nestler EJ (2013). "Epigenetic mechanisms of depression and antidepressant action". review. Annual Review of Pharmacology and Toxicology. 53: 59–87. doi:10.1146/annurev-pharmtox-010611-134540. PMC 3711377. PMID 23020296.
Szyf M, Weaver I, Meaney M (July 2007). "Maternal care, the epigenome and phenotypic differences in behavior". review. Reproductive Toxicology. 24 (1): 9–19. doi:10.1016/j.reprotox.2007.05.001. PMID 17561370.
Daskalakis NP, Cohen H, Nievergelt CM, Baker DG, Buxbaum JD, Russo SJ, et al. (October 2016). "New translational perspectives for blood-based biomarkers of PTSD: From glucocorticoid to immune mediators of stress susceptibility". review. Experimental Neurology. 284 (Pt B): 133–140. doi:10.1016/j.expneurol.2016.07.024. PMC 5056828. PMID 27481726.
Kim M, Costello J (April 2017). "DNA methylation: an epigenetic mark of cellular memory". Experimental & Molecular Medicine. 49 (4): e322. doi:10.1038/emm.2017.10. PMC 6130213. PMID 28450738.
Bellini E, Pavesi G, Barbiero I, Bergo A, Chandola C, Nawaz MS, et al. (2014). "MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?". review. Frontiers in Cellular Neuroscience. 8: 236. doi:10.3389/fncel.2014.00236. PMC 4131190. PMID 25165434.
Lee RS, Tamashiro KL, Yang X, Purcell RH, Huo Y, Rongione M, et al. (November 2011). "A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice". primary. Psychopharmacology. 218 (1): 303–312. doi:10.1007/s00213-011-2307-3. PMC 3918452. PMID 21509501.
Sipahi L, Wildman DE, Aiello AE, Koenen KC, Galea S, Abbas A, et al. (November 2014). "Longitudinal epigenetic variation of DNA methyltransferase genes is associated with vulnerability to post-traumatic stress disorder". primary. Psychological Medicine. 44 (15): 3165–3179. doi:10.1017/S0033291714000968. PMC 4530981. PMID 25065861.
Weaver IC, Cervoni N, Champagne FA, D'Alessio AC, Sharma S, Seckl JR, et al. (August 2004). "Epigenetic programming by maternal behavior". primary. Nature Neuroscience. 7 (8): 847–854. doi:10.1038/nn1276. PMID 15220929. S2CID 1649281.
Zhang TY, Labonté B, Wen XL, Turecki G, Meaney MJ (January 2013). "Epigenetic mechanisms for the early environmental regulation of hippocampal glucocorticoid receptor gene expression in rodents and humans". review. Neuropsychopharmacology. 38 (1): 111–123. doi:10.1038/npp.2012.149. PMC 3521971. PMID 22968814.
Levine A, Worrell TR, Zimnisky R, Schmauss C (January 2012). "Early life stress triggers sustained changes in histone deacetylase expression and histone H4 modifications that alter responsiveness to adolescent antidepressant treatment". primary. Neurobiology of Disease. 45 (1): 488–498. doi:10.1016/j.nbd.2011.09.005. PMC 3225638. PMID 21964251.
Tesone-Coelho C, Morel LJ, Bhatt J, Estevez L, Naudon L, Giros B, et al. (January 2015). "Vulnerability to opiate intake in maternally deprived rats: implication of MeCP2 and of histone acetylation". primary. Addiction Biology. 20 (1): 120–131. doi:10.1111/adb.12084. PMID 23980619. S2CID 5938827.
Suri D, Bhattacharya A, Vaidya VA (February 2014). "Early stress evokes temporally distinct consequences on the hippocampal transcriptome, anxiety and cognitive behaviour". primary. The International Journal of Neuropsychopharmacology. 17 (2): 289–301. doi:10.1017/S1461145713001004. PMID 24025219.
Smeeth D, Beck S, Karam EG, Pluess M (July 2021). "The role of epigenetics in psychological resilience". The Lancet Psychiatry. 8 (7): 620–629. doi:10.1016/S2215-0366(20)30515-0. PMC 9561637. PMID 33915083.
Jawaid A, Roszkowski M, Mansuy IM (2018). "Transgenerational Epigenetics of Traumatic Stress". Progress in Molecular Biology and Translational Science. 158. Elsevier: 273–298. doi:10.1016/bs.pmbts.2018.03.003. ISBN 978-0-12-812592-2. PMID 30072057.
Wang F, Pan F, Tang Y, Huang JH (2021). "Editorial: Early Life Stress-Induced Epigenetic Changes Involved in Mental Disorders". Frontiers in Genetics. 12: 684844. doi:10.3389/fgene.2021.684844. PMC 8320347. PMID 34335692.
Grezenko H, Ekhator C, Nwabugwu NU, Ganga H, Affaf M, Abdelaziz AM, et al. (August 2023). "Epigenetics in Neurological and Psychiatric Disorders: A Comprehensive Review of Current Understanding and Future Perspectives". Cureus. 15 (8): e43960. doi:10.7759/cureus.43960. PMC 10446850. PMID 37622055.
Yeshurun S, Hannan AJ (April 2019). "Transgenerational epigenetic influences of paternal environmental exposures on brain function and predisposition to psychiatric disorders". review. Molecular Psychiatry. 24 (4): 536–548. doi:10.1038/s41380-018-0039-z. PMID 29520039. S2CID 3767345.
Yahyavi ST, Zarghami M, Marwah U (2013). "A review on the evidence of transgenerational transmission of posttraumatic stress disorder vulnerability". review. Revista Brasileira de Psiquiatria. 36 (1): 89–94. doi:10.1590/1516-4446-2012-0995. PMID 24402183.
Li SC (November 2013). "Neuromodulation and developmental contextual influences on neural and cognitive plasticity across the lifespan". review. Neuroscience and Biobehavioral Reviews. 37 (9 Pt B): 2201–2208. doi:10.1016/j.neubiorev.2013.07.019. PMID 23973556. S2CID 46501356.
Kellermann NP (2013). "Epigenetic transmission of Holocaust trauma: can nightmares be inherited?". review. The Israel Journal of Psychiatry and Related Sciences. 50 (1): 33–39. PMID 24029109.
Hodes GE, Walker DM, Labonté B, Nestler EJ, Russo SJ (January 2017). "Understanding the epigenetic basis of sex differences in depression". review. Journal of Neuroscience Research. 95 (1–2): 692–702. doi:10.1002/jnr.23876. PMC 5130105. PMID 27870456.
Duncan EJ, Gluckman PD, Dearden PK (June 2014). "Epigenetics, plasticity, and evolution: How do we link epigenetic change to phenotype?". Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution. 322 (4): 208–220. doi:10.1002/jez.b.22571. ISSN 1552-5015. PMID 24719220.
Yehuda R, Halligan SL, Bierer LM (2001). "Relationship of parental trauma exposure and PTSD to PTSD, depressive and anxiety disorders in offspring". primary. Journal of Psychiatric Research. 35 (5): 261–270. doi:10.1016/S0022-3956(01)00032-2. PMID 11591428.
Yehuda R, Bierer LM (2008). "Transgenerational transmission of cortisol and PTSD risk". Stress Hormones and Post Traumatic Stress Disorder Basic Studies and Clinical Perspectives. review. Progress in Brain Research. Vol. 167. pp. 121–35. doi:10.1016/S0079-6123(07)67009-5. ISBN 978-0-444-53140-7. PMID 18037011.
Yehuda R, Daskalakis NP, Lehrner A, Desarnaud F, Bader HN, Makotkine I, et al. (August 2014). "Influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in Holocaust survivor offspring". primary. The American Journal of Psychiatry. 171 (8): 872–880. doi:10.1176/appi.ajp.2014.13121571. PMC 4127390. PMID 24832930.
Bierer LM, Bader HN, Daskalakis NP, Lehrner A, Provençal N, Wiechmann T, et al. (August 2020). "Intergenerational Effects of Maternal Holocaust Exposure on FKBP5 Methylation". The American Journal of Psychiatry. 177 (8): 744–753. doi:10.1176/appi.ajp.2019.19060618. PMID 32312110.
Kellermann NP (August 2001). "Transmission of Holocaust trauma--an integrative view". Psychiatry. 64 (3): 256–267. doi:10.1521/psyc.64.3.256.18464. PMID 11708051.
Franklin TB, Russig H, Weiss IC, Gräff J, Linder N, Michalon A, et al. (September 2010). "Epigenetic transmission of the impact of early stress across generations". primary. Biological Psychiatry. 68 (5): 408–415. doi:10.1016/j.biopsych.2010.05.036. PMID 20673872. S2CID 15851484.
Yuan TF, Li A, Sun X, Ouyang H, Campos C, Rocha NB, et al. (November 2016). "Transgenerational Inheritance of Paternal Neurobehavioral Phenotypes: Stress, Addiction, Ageing and Metabolism". review. Molecular Neurobiology. 53 (9): 6367–6376. doi:10.1007/s12035-015-9526-2. hdl:10400.22/7331. PMID 26572641. S2CID 25694221.
Gapp K, Jawaid A, Sarkies P, Bohacek J, Pelczar P, Prados J, et al. (May 2014). "Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice". primary. Nature Neuroscience. 17 (5): 667–669. doi:10.1038/nn.3695. PMC 4333222. PMID 24728267.
Sharma U, Rando OJ (June 2014). "Father-son chats: inheriting stress through sperm RNA". comment. Cell Metabolism. 19 (6): 894–895. doi:10.1016/j.cmet.2014.05.015. PMC 4131544. PMID 24896534.
Short AK, Yeshurun S, Powell R, Perreau VM, Fox A, Kim JH, et al. (May 2017). "Exercise alters mouse sperm small noncoding RNAs and induces a transgenerational modification of male offspring conditioned fear and anxiety". primary. Translational Psychiatry. 7 (5): e1114. doi:10.1038/tp.2017.82. PMC 5534950. PMID 28463242.
Zschucke E, Renneberg B, Dimeo F, Wüstenberg T, Ströhle A (January 2015). "The stress-buffering effect of acute exercise: Evidence for HPA axis negative feedback". Psychoneuroendocrinology. This issue includes a Special Section on Biomarkers in the Military - New Findings from Prospective Studies. 51: 414–425. doi:10.1016/j.psyneuen.2014.10.019. PMID 25462913.
Gapp K, Bohacek J, Grossmann J, Brunner AM, Manuella F, Nanni P, et al. (October 2016). "Potential of Environmental Enrichment to Prevent Transgenerational Effects of Paternal Trauma". primary. Neuropsychopharmacology. 41 (11): 2749–2758. doi:10.1038/npp.2016.87. PMC 5026744. PMID 27277118.
Mitchell C, Schneper LM, Notterman DA (January 2016). "DNA methylation, early life environment, and health outcomes". review. Pediatric Research. 79 (1–2): 212–219. doi:10.1038/pr.2015.193. PMC 4798238. PMID 26466079.
Johnstone SE, Baylin SB (November 2010). "Stress and the epigenetic landscape: a link to the pathobiology of human diseases?". Nature Reviews. Genetics. 11 (11): 806–812. doi:10.1038/nrg2881. PMC 3148009. PMID 20921961.
Jiang S, Postovit L, Cattaneo A, Binder EB, Aitchison KJ (2019). "Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma". Frontiers in Psychiatry. 10: 808. doi:10.3389/fpsyt.2019.00808. PMC 6857662. PMID 31780969.
Daskalakis NP, Cohen H, Nievergelt CM, Baker DG, Buxbaum JD, Russo SJ, et al. (October 2016). "New translational perspectives for blood-based biomarkers of PTSD: From glucocorticoid to immune mediators of stress susceptibility". Experimental Neurology. Special Issue: New Perspectives in PTSD. 284 (Pt B): 133–140. doi:10.1016/j.expneurol.2016.07.024. PMC 5056828. PMID 27481726.
Katrinli S, Zheng Y, Gautam A, Hammamieh R, Yang R, Venkateswaran S, et al. (January 2021). "PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L". Brain, Behavior, and Immunity. 91: 429–436. doi:10.1016/j.bbi.2020.10.023. PMC 7749859. PMID 33152445.
Greer CB, Wright J, Weiss JD, Lazarenko RM, Moran SP, Zhu J, et al. (January 2021). "Tet1 Isoforms Differentially Regulate Gene Expression, Synaptic Transmission, and Memory in the Mammalian Brain". The Journal of Neuroscience. 41 (4): 578–593. doi:10.1523/JNEUROSCI.1821-20.2020. PMC 7842754. PMID 33262245.
Zannas AS, Provençal N, Binder EB (September 2015). "Epigenetics of Posttraumatic Stress Disorder: Current Evidence, Challenges, and Future Directions". review. Biological Psychiatry. 78 (5): 327–335. doi:10.1016/j.biopsych.2015.04.003. PMID 25979620. S2CID 20876167.
Koenen KC, Uddin M, Chang SC, Aiello AE, Wildman DE, Goldmann E, et al. (August 2011). "SLC6A4 methylation modifies the effect of the number of traumatic events on risk for posttraumatic stress disorder". review. Depression and Anxiety. 28 (8): 639–647. doi:10.1002/da.20825. PMC 3145829. PMID 21608084.
Uddin M, Galea S, Chang SC, Aiello AE, Wildman DE, de los Santos R, et al. (2011). "Gene expression and methylation signatures of MAN2C1 are associated with PTSD". primary. Disease Markers. 30 (2–3): 111–121. doi:10.1155/2011/513659. PMC 3188659. PMID 21508515.
Smith AK, Conneely KN, Kilaru V, Mercer KB, Weiss TE, Bradley B, et al. (September 2011). "Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder". primary. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 156B (6): 700–708. doi:10.1002/ajmg.b.31212. PMC 3292872. PMID 21714072.
Ressler KJ, Mercer KB, Bradley B, Jovanovic T, Mahan A, Kerley K, et al. (February 2011). "Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor". primary. Nature. 470 (7335): 492–497. Bibcode:2011Natur.470..492R. doi:10.1038/nature09856. PMC 3046811. PMID 21350482.
Rusiecki JA, Chen L, Srikantan V, Zhang L, Yan L, Polin ML, et al. (February 2012). "DNA methylation in repetitive elements and post-traumatic stress disorder: a case-control study of US military service members". primary. Epigenomics. 4 (1): 29–40. doi:10.2217/epi.11.116. PMC 3809831. PMID 22332656.
Chang SC, Koenen KC, Galea S, Aiello AE, Soliven R, Wildman DE, et al. (2012). "Molecular variation at the SLC6A3 locus predicts lifetime risk of PTSD in the Detroit Neighborhood Health Study". primary. PLOS ONE. 7 (6): e39184. Bibcode:2012PLoSO...739184C. doi:10.1371/journal.pone.0039184. PMC 3383758. PMID 22745713.
Rusiecki JA, Byrne C, Galdzicki Z, Srikantan V, Chen L, Poulin M, et al. (2013). "PTSD and DNA Methylation in Select Immune Function Gene Promoter Regions: A Repeated Measures Case-Control Study of U.S. Military Service Members". primary. Frontiers in Psychiatry. 4: 56. doi:10.3389/fpsyt.2013.00056. PMC 3690381. PMID 23805108.
Labonté B, Azoulay N, Yerko V, Turecki G, Brunet A (March 2014). "Epigenetic modulation of glucocorticoid receptors in posttraumatic stress disorder". primary. Translational Psychiatry. 4 (3): e368. doi:10.1038/tp.2014.3. PMC 3966043. PMID 24594779.
Yehuda R, Flory JD, Bierer LM, Henn-Haase C, Lehrner A, Desarnaud F, et al. (February 2015). "Lower methylation of glucocorticoid receptor gene promoter 1F in peripheral blood of veterans with posttraumatic stress disorder". primary. Biological Psychiatry. 77 (4): 356–364. doi:10.1016/j.biopsych.2014.02.006. PMID 24661442. S2CID 38006995.
Vukojevic V, Kolassa IT, Fastenrath M, Gschwind L, Spalek K, Milnik A, et al. (July 2014). "Epigenetic modification of the glucocorticoid receptor gene is linked to traumatic memory and post-traumatic stress disorder risk in genocide survivors". primary. The Journal of Neuroscience. 34 (31): 10274–10284. doi:10.1523/JNEUROSCI.1526-14.2014. PMC 6608273. PMID 25080589.
Blacker CJ, Frye MA, Morava E, Kozicz T, Veldic M (February 2019). "A Review of Epigenetics of PTSD in Comorbid Psychiatric Conditions". Genes. 10 (2): 140. doi:10.3390/genes10020140. PMC 6410143. PMID 30781888.
Dunlop BW, Wong A (March 2019). "The hypothalamic-pituitary-adrenal axis in PTSD: Pathophysiology and treatment interventions". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 89: 361–379. doi:10.1016/j.pnpbp.2018.10.010. PMID 30342071. S2CID 53044044.
Uddin M, Aiello AE, Wildman DE, Koenen KC, Pawelec G, de Los Santos R, et al. (May 2010). "Epigenetic and immune function profiles associated with posttraumatic stress disorder". primary. Proceedings of the National Academy of Sciences of the United States of America. 107 (20): 9470–9475. Bibcode:2010PNAS..107.9470U. doi:10.1073/pnas.0910794107. PMC 2889041. PMID 20439746.
Blouin AM, Sillivan SE, Joseph NF, Miller CA (October 2016). "The potential of epigenetics in stress-enhanced fear learning models of PTSD". Learning & Memory. 23 (10): 576–586. doi:10.1101/lm.040485.115. PMC 5026205. PMID 27634148.
Yehuda R, Daskalakis NP, Desarnaud F, Makotkine I, Lehrner AL, Koch E, et al. (2013). "Epigenetic Biomarkers as Predictors and Correlates of Symptom Improvement Following Psychotherapy in Combat Veterans with PTSD". primary. Frontiers in Psychiatry. 4: 118. doi:10.3389/fpsyt.2013.00118. PMC 3784793. PMID 24098286.
Zannas AS, Binder EB (January 2014). "Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism". review. Genes, Brain and Behavior. 13 (1): 25–37. doi:10.1111/gbb.12104. PMID 24219237. S2CID 41781060.
Zhang X, Clark AF, Yorio T (March 2008). "FK506-binding protein 51 regulates nuclear transport of the glucocorticoid receptor beta and glucocorticoid responsiveness". Investigative Ophthalmology & Visual Science. 49 (3): 1037–1047. doi:10.1167/iovs.07-1279. PMC 2442563. PMID 18326728.
Wochnik GM, Rüegg J, Abel GA, Schmidt U, Holsboer F, Rein T (February 2005). "FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells". primary. The Journal of Biological Chemistry. 280 (6): 4609–4616. doi:10.1074/jbc.M407498200. PMID 15591061.
Xie P, Kranzler HR, Poling J, Stein MB, Anton RF, Farrer LA, et al. (July 2010). "Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder". primary. Neuropsychopharmacology. 35 (8): 1684–1692. doi:10.1038/npp.2010.37. PMC 2946626. PMID 20393453.
Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, Mercer KB, et al. (March 2008). "Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults". primary. JAMA. 299 (11): 1291–1305. doi:10.1001/jama.299.11.1291. PMC 2441757. PMID 18349090.
Boscarino JA, Erlich PM, Hoffman SN, Zhang X (2012). "Higher FKBP5, COMT, CHRNA5, and CRHR1 allele burdens are associated with PTSD and interact with trauma exposure: implications for neuropsychiatric research and treatment". primary. Neuropsychiatric Disease and Treatment. 8: 131–139. doi:10.2147/NDT.S29508. PMC 3333786. PMID 22536069.
Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, et al. (January 2013). "Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions". primary. Nature Neuroscience. 16 (1): 33–41. doi:10.1038/nn.3275. PMC 4136922. PMID 23201972.
Longley MJ, Lee J, Jung J, Lohoff FW (November 2021). "Epigenetics of alcohol use disorder—A review of recent advances in DNA methylation profiling". Addiction Biology. 26 (6): e13006. doi:10.1111/adb.13006. ISSN 1355-6215. PMC 8596445. PMID 33538087.
Palmisano M, Pandey SC (May 2017). "Epigenetic mechanisms of alcoholism and stress-related disorders". review. Alcohol. 60: 7–18. doi:10.1016/j.alcohol.2017.01.001. PMC 5464725. PMID 28477725.
Agudelo M, Figueroa G, Parira T, Yndart A, Muñoz K, Atluri V, et al. (2016). "Profile of Class I Histone Deacetylases (HDAC) by Human Dendritic Cells after Alcohol Consumption and In Vitro Alcohol Treatment and Their Implication in Oxidative Stress: Role of HDAC Inhibitors Trichostatin A and Mocetinostat". primary. PLOS ONE. 11 (6): e0156421. Bibcode:2016PLoSO..1156421A. doi:10.1371/journal.pone.0156421. PMC 4889108. PMID 27249803.
Moonat S, Sakharkar AJ, Zhang H, Tang L, Pandey SC (April 2013). "Aberrant histone deacetylase2-mediated histone modifications and synaptic plasticity in the amygdala predisposes to anxiety and alcoholism". primary. Biological Psychiatry. 73 (8): 763–773. doi:10.1016/j.biopsych.2013.01.012. PMC 3718567. PMID 23485013.
Moonat S, Pandey SC (2012). "Stress, epigenetics, and alcoholism". review. Alcohol Research. 34 (4): 495–505. PMC 3860391. PMID 23584115.
Pandey SC, Ugale R, Zhang H, Tang L, Prakash A (April 2008). "Brain chromatin remodeling: a novel mechanism of alcoholism". primary. The Journal of Neuroscience. 28 (14): 3729–3737. doi:10.1523/JNEUROSCI.5731-07.2008. PMC 6671100. PMID 18385331.
Maron E, Nutt D (September 2015). "Biological predictors of pharmacological therapy in anxiety disorders". Dialogues in Clinical Neuroscience. 17 (3): 305–317. doi:10.31887/DCNS.2015.17.3/emaron. PMC 4610615. PMID 26487811.
Roy-Byrne P (June 2015). "Treatment-refractory anxiety; definition, risk factors, and treatment challenges". Dialogues in Clinical Neuroscience. 17 (2): 191–206. doi:10.31887/DCNS.2015.17.2/proybyrne. PMC 4518702. PMID 26246793.
Peedicayil J (March 2020). "The Potential Role of Epigenetic Drugs in the Treatment of Anxiety Disorders". Neuropsychiatric Disease and Treatment. 16 (16): 597–606. doi:10.2147/NDT.S242040. PMC 7060022. PMID 32184601.
Eckschlager T, Plch J, Stiborova M, Hrabeta J (July 2017). "Histone Deacetylase Inhibitors as Anticancer Drugs". International Journal of Molecular Sciences. 18 (7): 1414. doi:10.3390/ijms18071414. PMC 5535906. PMID 28671573.
Rajan A, Shi H, Xue B (August 2018). "Class I and II Histone Deacetylase Inhibitors Differentially Regulate Thermogenic Gene Expression in Brown Adipocytes". Scientific Reports. 8 (1): 13072. Bibcode:2018NatSR...813072R. doi:10.1038/s41598-018-31560-w. PMC 6117331. PMID 30166563.
Wei Y, Melas PA, Wegener G, Mathé AA, Lavebratt C (October 2014). "Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene". The International Journal of Neuropsychopharmacology. 18 (2): pyu032. doi:10.1093/ijnp/pyu032. PMC 4368891. PMID 25618518.
Primeau F, Fontaine R, Beauclair L (April 1990). "Valproic acid and panic disorder". Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie. 35 (3): 248–250. doi:10.1177/070674379003500309. PMID 2111204. S2CID 37695090.
Woodman CL, Noyes R (April 1994). "Panic disorder: treatment with valproate". The Journal of Clinical Psychiatry. 55 (4): 134–136. PMID 8071256.
Keck PE, Taylor VE, Tugrul KC, McElroy SL, Bennett JA (April 1993). "Valproate treatment of panic disorder and lactate-induced panic attacks". Biological Psychiatry. 33 (7): 542–546. doi:10.1016/0006-3223(93)90010-B. PMID 8513040. S2CID 1411404.
Kinrys G, Pollack MH, Simon NM, Worthington JJ, Nardi AE, Versiani M (May 2003). "Valproic acid for the treatment of social anxiety disorder". International Clinical Psychopharmacology. 18 (3): 169–172. doi:10.1097/01.yic.0000064261.66765.9f. PMID 12702897. S2CID 43035988.
Aliyev NA, Aliyev ZN (March 2008). "Valproate (depakine-chrono) in the acute treatment of outpatients with generalized anxiety disorder without psychiatric comorbidity: randomized, double-blind placebo-controlled study". European Psychiatry. 23 (2): 109–114. doi:10.1016/j.eurpsy.2007.08.001. PMID 17945470. S2CID 20266182.
Bach DR, Korn CW, Vunder J, Bantel A (August 2018). "Effect of valproate and pregabalin on human anxiety-like behaviour in a randomised controlled trial". Translational Psychiatry. 8 (1): 157. doi:10.1038/s41398-018-0206-7. PMC 6095858. PMID 30115911.
Whittle N, Schmuckermair C, Gunduz Cinar O, Hauschild M, Ferraguti F, Holmes A, et al. (January 2013). "Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model". Neuropharmacology. 64 (4): 414–423. doi:10.1016/j.neuropharm.2012.06.001. PMC 3474950. PMID 22722028.
You C, Zhang H, Sakharkar AJ, Teppen T, Pandey SC (February 2014). "Reversal of deficits in dendritic spines, BDNF and Arc expression in the amygdala during alcohol dependence by HDAC inhibitor treatment". The International Journal of Neuropsychopharmacology. 17 (2): 313–322. doi:10.1017/S1461145713001144. PMC 4093912. PMID 24103311.
Moloney RD, Stilling RM, Dinan TG, Cryan JF (December 2015). "Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition". Neurogastroenterology and Motility. 27 (12): 1831–1836. doi:10.1111/nmo.12675. PMID 26403543. S2CID 30923705.
Hayase T (July 2016). "Putative Epigenetic Involvement of the Endocannabinoid System in Anxiety- and Depression-Related Behaviors Caused by Nicotine as a Stressor". PLOS ONE. 11 (7): e0158950. Bibcode:2016PLoSO..1158950H. doi:10.1371/journal.pone.0158950. PMC 4942073. PMID 27404492.
Karnib N, El-Ghandour R, El Hayek L, Nasrallah P, Khalifeh M, Barmo N, et al. (May 2019). "Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases". Neuropsychopharmacology. 44 (6): 1152–1162. doi:10.1038/s41386-019-0313-z. PMC 6461925. PMID 30647450.
Baud O, Watterberg KL (June 2019). "Prophylactic postnatal corticosteroids: Early hydrocortisone". Seminars in Fetal & Neonatal Medicine. 24 (3): 202–206. doi:10.1016/j.siny.2019.04.007. PMID 31043325.
Kothgassner OD, Pellegrini M, Goreis A, Giordano V, Edobor J, Fischer S, et al. (April 2021). "Hydrocortisone administration for reducing post-traumatic stress symptoms: A systematic review and meta-analysis". Psychoneuroendocrinology. 126: 105168. doi:10.1016/j.psyneuen.2021.105168. PMID 33626392. S2CID 231930081.
Zohar J, Yahalom H, Kozlovsky N, Cwikel-Hamzany S, Matar MA, Kaplan Z, et al. (November 2011). "High dose hydrocortisone immediately after trauma may alter the trajectory of PTSD: interplay between clinical and animal studies". European Neuropsychopharmacology. 21 (11): 796–809. doi:10.1016/j.euroneuro.2011.06.001. PMID 21741804. S2CID 32595065.
Al Jowf GI, Snijders C, Rutten BP, de Nijs L, Eijssen LM (October 2021). "The Molecular Biology of Susceptibility to Post-Traumatic Stress Disorder: Highlights of Epigenetics and Epigenomics". International Journal of Molecular Sciences. 22 (19): 10743. doi:10.3390/ijms221910743. PMC 8509551. PMID 34639084.
Youssef NA (March 2022). "Potential Societal and Cultural Implications of Transgenerational Epigenetic Methylation of Trauma and PTSD: Pathology or Resilience?". The Yale Journal of Biology and Medicine. 95 (1): 171–174. PMC 8961703. PMID 35370497.
Tortella-Feliu M, Fullana MA, Pérez-Vigil A, Torres X, Chamorro J, Littarelli SA, et al. (December 2019). "Risk factors for posttraumatic stress disorder: An umbrella review of systematic reviews and meta-analyses". Neuroscience and Biobehavioral Reviews. 107: 154–165. doi:10.1016/j.neubiorev.2019.09.013. PMID 31520677. S2CID 202558369.

semanticscholar.org

api.semanticscholar.org

Matthews SG, Phillips DI (January 2012). "Transgenerational inheritance of stress pathology". review. Experimental Neurology. 233 (1): 95–101. doi:10.1016/j.expneurol.2011.01.009. PMID 21281632. S2CID 30261742.
Weaver IC, Cervoni N, Champagne FA, D'Alessio AC, Sharma S, Seckl JR, et al. (August 2004). "Epigenetic programming by maternal behavior". primary. Nature Neuroscience. 7 (8): 847–854. doi:10.1038/nn1276. PMID 15220929. S2CID 1649281.
Tesone-Coelho C, Morel LJ, Bhatt J, Estevez L, Naudon L, Giros B, et al. (January 2015). "Vulnerability to opiate intake in maternally deprived rats: implication of MeCP2 and of histone acetylation". primary. Addiction Biology. 20 (1): 120–131. doi:10.1111/adb.12084. PMID 23980619. S2CID 5938827.
Yeshurun S, Hannan AJ (April 2019). "Transgenerational epigenetic influences of paternal environmental exposures on brain function and predisposition to psychiatric disorders". review. Molecular Psychiatry. 24 (4): 536–548. doi:10.1038/s41380-018-0039-z. PMID 29520039. S2CID 3767345.
Li SC (November 2013). "Neuromodulation and developmental contextual influences on neural and cognitive plasticity across the lifespan". review. Neuroscience and Biobehavioral Reviews. 37 (9 Pt B): 2201–2208. doi:10.1016/j.neubiorev.2013.07.019. PMID 23973556. S2CID 46501356.
Franklin TB, Russig H, Weiss IC, Gräff J, Linder N, Michalon A, et al. (September 2010). "Epigenetic transmission of the impact of early stress across generations". primary. Biological Psychiatry. 68 (5): 408–415. doi:10.1016/j.biopsych.2010.05.036. PMID 20673872. S2CID 15851484.
Yuan TF, Li A, Sun X, Ouyang H, Campos C, Rocha NB, et al. (November 2016). "Transgenerational Inheritance of Paternal Neurobehavioral Phenotypes: Stress, Addiction, Ageing and Metabolism". review. Molecular Neurobiology. 53 (9): 6367–6376. doi:10.1007/s12035-015-9526-2. hdl:10400.22/7331. PMID 26572641. S2CID 25694221.
Zannas AS, Provençal N, Binder EB (September 2015). "Epigenetics of Posttraumatic Stress Disorder: Current Evidence, Challenges, and Future Directions". review. Biological Psychiatry. 78 (5): 327–335. doi:10.1016/j.biopsych.2015.04.003. PMID 25979620. S2CID 20876167.
Yehuda R, Flory JD, Bierer LM, Henn-Haase C, Lehrner A, Desarnaud F, et al. (February 2015). "Lower methylation of glucocorticoid receptor gene promoter 1F in peripheral blood of veterans with posttraumatic stress disorder". primary. Biological Psychiatry. 77 (4): 356–364. doi:10.1016/j.biopsych.2014.02.006. PMID 24661442. S2CID 38006995.
Dunlop BW, Wong A (March 2019). "The hypothalamic-pituitary-adrenal axis in PTSD: Pathophysiology and treatment interventions". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 89: 361–379. doi:10.1016/j.pnpbp.2018.10.010. PMID 30342071. S2CID 53044044.
Zannas AS, Binder EB (January 2014). "Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism". review. Genes, Brain and Behavior. 13 (1): 25–37. doi:10.1111/gbb.12104. PMID 24219237. S2CID 41781060.
Primeau F, Fontaine R, Beauclair L (April 1990). "Valproic acid and panic disorder". Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie. 35 (3): 248–250. doi:10.1177/070674379003500309. PMID 2111204. S2CID 37695090.
Keck PE, Taylor VE, Tugrul KC, McElroy SL, Bennett JA (April 1993). "Valproate treatment of panic disorder and lactate-induced panic attacks". Biological Psychiatry. 33 (7): 542–546. doi:10.1016/0006-3223(93)90010-B. PMID 8513040. S2CID 1411404.
Kinrys G, Pollack MH, Simon NM, Worthington JJ, Nardi AE, Versiani M (May 2003). "Valproic acid for the treatment of social anxiety disorder". International Clinical Psychopharmacology. 18 (3): 169–172. doi:10.1097/01.yic.0000064261.66765.9f. PMID 12702897. S2CID 43035988.
Aliyev NA, Aliyev ZN (March 2008). "Valproate (depakine-chrono) in the acute treatment of outpatients with generalized anxiety disorder without psychiatric comorbidity: randomized, double-blind placebo-controlled study". European Psychiatry. 23 (2): 109–114. doi:10.1016/j.eurpsy.2007.08.001. PMID 17945470. S2CID 20266182.
Moloney RD, Stilling RM, Dinan TG, Cryan JF (December 2015). "Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition". Neurogastroenterology and Motility. 27 (12): 1831–1836. doi:10.1111/nmo.12675. PMID 26403543. S2CID 30923705.
Kothgassner OD, Pellegrini M, Goreis A, Giordano V, Edobor J, Fischer S, et al. (April 2021). "Hydrocortisone administration for reducing post-traumatic stress symptoms: A systematic review and meta-analysis". Psychoneuroendocrinology. 126: 105168. doi:10.1016/j.psyneuen.2021.105168. PMID 33626392. S2CID 231930081.
Zohar J, Yahalom H, Kozlovsky N, Cwikel-Hamzany S, Matar MA, Kaplan Z, et al. (November 2011). "High dose hydrocortisone immediately after trauma may alter the trajectory of PTSD: interplay between clinical and animal studies". European Neuropsychopharmacology. 21 (11): 796–809. doi:10.1016/j.euroneuro.2011.06.001. PMID 21741804. S2CID 32595065.
Tortella-Feliu M, Fullana MA, Pérez-Vigil A, Torres X, Chamorro J, Littarelli SA, et al. (December 2019). "Risk factors for posttraumatic stress disorder: An umbrella review of systematic reviews and meta-analyses". Neuroscience and Biobehavioral Reviews. 107: 154–165. doi:10.1016/j.neubiorev.2019.09.013. PMID 31520677. S2CID 202558369.

web.archive.org

Liddell BJ, Jobson L (2016-06-13). "The impact of cultural differences in self-representation on the neural substrates of posttraumatic stress disorder". European Journal of Psychotraumatology. 7 (1). doi:10.3402/ejpt.v7.30464. ISSN 2000-8066. PMC 4908066. Archived from the original on 2025-02-03.

worldcat.org

search.worldcat.org

Duncan EJ, Gluckman PD, Dearden PK (June 2014). "Epigenetics, plasticity, and evolution: How do we link epigenetic change to phenotype?". Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution. 322 (4): 208–220. doi:10.1002/jez.b.22571. ISSN 1552-5015. PMID 24719220.
Zhang Y, Zhao G, Han Y, Zhang J, Cao C, Wang L, et al. (2022). "The mechanisms of histone modification in post-traumatic stress disorder". Advances in Psychological Science. 30 (1): 98–114. doi:10.3724/SP.J.1042.2022.00098. ISSN 1671-3710.
Liddell BJ, Jobson L (2016-06-13). "The impact of cultural differences in self-representation on the neural substrates of posttraumatic stress disorder". European Journal of Psychotraumatology. 7 (1). doi:10.3402/ejpt.v7.30464. ISSN 2000-8066. PMC 4908066. Archived from the original on 2025-02-03.
Longley MJ, Lee J, Jung J, Lohoff FW (November 2021). "Epigenetics of alcohol use disorder—A review of recent advances in DNA methylation profiling". Addiction Biology. 26 (6): e13006. doi:10.1111/adb.13006. ISSN 1355-6215. PMC 8596445. PMID 33538087.