FNDC5 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "FNDC5" in English language version.

refsWebsite

Global rank English rank

39nih.gov

4^th place

22doi.org

2^nd place

5harvard.edu

18^th place

17^th place

5semanticscholar.org

11^th place

8^th place

2ensembl.org

1,626^th place

1,007^th place

2nytimes.com

7^th place

1scientificamerican.com

896^th place

674^th place

1web.archive.org

1^st place

1time.com

61^st place

54^th place

1medicalxpress.com

8,255^th place

low place

doi.org

Erickson HP (October 2013). "Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?". Adipocyte. 2 (4): 289–293. doi:10.4161/adip.26082. PMC 3774709. PMID 24052909.
Farrash W, Brook M, Crossland H, Phillips BE, Cegielski J, Wilkinson DJ, et al. (June 2020). "Impacts of rat hindlimb Fndc5/irisin overexpression on muscle and adipose tissue metabolism". American Journal of Physiology. Endocrinology and Metabolism. 318 (6): E943 – E955. doi:10.1152/ajpendo.00034.2020. PMC 7311674. PMID 32369414.
Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. (January 2012). "A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis". Nature. 481 (7382): 463–468. Bibcode:2012Natur.481..463B. doi:10.1038/nature10777. PMC 3522098. PMID 22237023.
Jedrychowski MP, Wrann CD, Paulo JA, Gerber KK, Szpyt J, Robinson MM, et al. (October 2015). "Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry". Cell Metabolism. 22 (4): 734–740. doi:10.1016/j.cmet.2015.08.001. PMC 4802359. PMID 26278051.
Teufel A, Malik N, Mukhopadhyay M, Westphal H (September 2002). "Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes". Gene. 297 (1–2): 79–83. doi:10.1016/S0378-1119(02)00828-4. PMID 12384288.
Ferrer-Martínez A, Ruiz-Lozano P, Chien KR (June 2002). "Mouse PeP: a novel peroxisomal protein linked to myoblast differentiation and development". Developmental Dynamics. 224 (2): 154–167. doi:10.1002/dvdy.10099. PMID 12112469. S2CID 42445530.
Zhang Y, Li R, Meng Y, Li S, Donelan W, Zhao Y, et al. (February 2014). "Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling". Diabetes. 63 (2): 514–525. doi:10.2337/db13-1106. PMID 24150604.
Wrann CD, White JP, Salogiannnis J, Laznik-Bogoslavski D, Wu J, Ma D, et al. (November 2013). "Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway". Cell Metabolism. 18 (5): 649–659. doi:10.1016/j.cmet.2013.09.008. PMC 3980968. PMID 24120943.
Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang AH, et al. (July 2012). "Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human". Cell. 150 (2): 366–376. doi:10.1016/j.cell.2012.05.016. PMC 3402601. PMID 22796012.
Zhang Y, Xie C, Wang H, Foss RM, Clare M, George EV, et al. (August 2016). "Irisin exerts dual effects on browning and adipogenesis of human white adipocytes". American Journal of Physiology. Endocrinology and Metabolism. 311 (2): E530 – E541. doi:10.1152/ajpendo.00094.2016. PMID 27436609. S2CID 3433786.
Timmons JA, Baar K, Davidsen PK, Atherton PJ (August 2012). "Is irisin a human exercise gene?". Nature. 488 (7413): E9-10, discussion E10-1. Bibcode:2012Natur.488E...9T. doi:10.1038/nature11364. PMID 22932392. S2CID 4415979.
Albrecht E, Norheim F, Thiede B, Holen T, Ohashi T, Schering L, et al. (March 2015). "Irisin – a myth rather than an exercise-inducible myokine". Scientific Reports. 5: 8889. Bibcode:2015NatSR...5E8889A. doi:10.1038/srep08889. PMC 4352853. PMID 25749243.
Raschke S, Elsen M, Gassenhuber H, Sommerfeld M, Schwahn U, Brockmann B, et al. (2013). López-Lluch G (ed.). "Evidence against a beneficial effect of irisin in humans". PLOS ONE. 8 (9): e73680. Bibcode:2013PLoSO...873680R. doi:10.1371/journal.pone.0073680. PMC 3770677. PMID 24040023.
Maak S, Norheim F, Drevon CA, Erickson HP (July 2021). "Progress and Challenges in the Biology of FNDC5 and Irisin". Endocrine Reviews. 42 (4): 436–456. doi:10.1210/endrev/bnab003. PMC 8284618. PMID 33493316.
Islam MR, Valaris S, Young MF, Haley EB, Luo R, Bond SF, et al. (August 2021). "Exercise hormone irisin is a critical regulator of cognitive function". Nature Metabolism. 3 (8): 1058–1070. doi:10.1038/s42255-021-00438-z. PMC 10317538. PMID 34417591. S2CID 237254736.
Pedersen BK, Febbraio MA (October 2008). "Muscle as an endocrine organ: focus on muscle-derived interleukin-6". Physiological Reviews. 88 (4): 1379–1406. doi:10.1152/physrev.90100.2007. PMID 18923185.
Xiong Y, Wu Z, Zhang B, Wang C, Mao F, Liu X, et al. (May 2019). "Fndc5 loss-of-function attenuates exercise-induced browning of white adipose tissue in mice". FASEB Journal. 33 (5): 5876–5886. doi:10.1096/fj.201801754RR. PMID 30721625. S2CID 73444056.
Servick K (March 2015). "Biomedicine. Woes for 'exercise hormone'". Science. 347 (6228): 1299. doi:10.1126/science.347.6228.1299. PMID 25792309.
Colaianni G, Cuscito C, Mongelli T, Pignataro P, Buccoliero C, Liu P, et al. (September 2015). "The myokine irisin increases cortical bone mass". Proceedings of the National Academy of Sciences of the United States of America. 112 (39): 12157–12162. Bibcode:2015PNAS..11212157C. doi:10.1073/pnas.1516622112. PMC 4593131. PMID 26374841.
Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, et al. (December 2018). "Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors". Cell. 175 (7): 1756–1768.e17. doi:10.1530/ey.16.15.15. PMC 6298040. PMID 30550785.
Colaianni G, Sanesi L, Storlino G, Brunetti G, Colucci S, Grano M (May 2019). "Irisin and Bone: From Preclinical Studies to the Evaluation of Its Circulating Levels in Different Populations of Human Subjects". Cells. 8 (5): 451. doi:10.3390/cells8050451. PMC 6562988. PMID 31091695.
Huang L, Yan S, Luo L, Yang L (February 2019). "Irisin regulates the expression of BDNF and glycometabolism in diabetic rats". Molecular Medicine Reports. 19 (2): 1074–1082. doi:10.3892/mmr.2018.9743. PMC 6323232. PMID 30569121.

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000160097 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000001334 – Ensembl, May 2017

harvard.edu

ui.adsabs.harvard.edu

Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. (January 2012). "A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis". Nature. 481 (7382): 463–468. Bibcode:2012Natur.481..463B. doi:10.1038/nature10777. PMC 3522098. PMID 22237023.
Timmons JA, Baar K, Davidsen PK, Atherton PJ (August 2012). "Is irisin a human exercise gene?". Nature. 488 (7413): E9-10, discussion E10-1. Bibcode:2012Natur.488E...9T. doi:10.1038/nature11364. PMID 22932392. S2CID 4415979.
Albrecht E, Norheim F, Thiede B, Holen T, Ohashi T, Schering L, et al. (March 2015). "Irisin – a myth rather than an exercise-inducible myokine". Scientific Reports. 5: 8889. Bibcode:2015NatSR...5E8889A. doi:10.1038/srep08889. PMC 4352853. PMID 25749243.
Raschke S, Elsen M, Gassenhuber H, Sommerfeld M, Schwahn U, Brockmann B, et al. (2013). López-Lluch G (ed.). "Evidence against a beneficial effect of irisin in humans". PLOS ONE. 8 (9): e73680. Bibcode:2013PLoSO...873680R. doi:10.1371/journal.pone.0073680. PMC 3770677. PMID 24040023.
Colaianni G, Cuscito C, Mongelli T, Pignataro P, Buccoliero C, Liu P, et al. (September 2015). "The myokine irisin increases cortical bone mass". Proceedings of the National Academy of Sciences of the United States of America. 112 (39): 12157–12162. Bibcode:2015PNAS..11212157C. doi:10.1073/pnas.1516622112. PMC 4593131. PMID 26374841.

medicalxpress.com

"The hormone irisin is found to confer benefits of exercise on cognitive function". medicalxpress.com. Retrieved September 21, 2021.

nih.gov

pubmed.ncbi.nlm.nih.gov

Erickson HP (October 2013). "Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?". Adipocyte. 2 (4): 289–293. doi:10.4161/adip.26082. PMC 3774709. PMID 24052909.
Farrash W, Brook M, Crossland H, Phillips BE, Cegielski J, Wilkinson DJ, et al. (June 2020). "Impacts of rat hindlimb Fndc5/irisin overexpression on muscle and adipose tissue metabolism". American Journal of Physiology. Endocrinology and Metabolism. 318 (6): E943 – E955. doi:10.1152/ajpendo.00034.2020. PMC 7311674. PMID 32369414.
Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. (January 2012). "A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis". Nature. 481 (7382): 463–468. Bibcode:2012Natur.481..463B. doi:10.1038/nature10777. PMC 3522098. PMID 22237023.
Jedrychowski MP, Wrann CD, Paulo JA, Gerber KK, Szpyt J, Robinson MM, et al. (October 2015). "Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry". Cell Metabolism. 22 (4): 734–740. doi:10.1016/j.cmet.2015.08.001. PMC 4802359. PMID 26278051.
Teufel A, Malik N, Mukhopadhyay M, Westphal H (September 2002). "Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes". Gene. 297 (1–2): 79–83. doi:10.1016/S0378-1119(02)00828-4. PMID 12384288.
Ferrer-Martínez A, Ruiz-Lozano P, Chien KR (June 2002). "Mouse PeP: a novel peroxisomal protein linked to myoblast differentiation and development". Developmental Dynamics. 224 (2): 154–167. doi:10.1002/dvdy.10099. PMID 12112469. S2CID 42445530.
Zhang Y, Li R, Meng Y, Li S, Donelan W, Zhao Y, et al. (February 2014). "Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling". Diabetes. 63 (2): 514–525. doi:10.2337/db13-1106. PMID 24150604.
Wrann CD, White JP, Salogiannnis J, Laznik-Bogoslavski D, Wu J, Ma D, et al. (November 2013). "Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway". Cell Metabolism. 18 (5): 649–659. doi:10.1016/j.cmet.2013.09.008. PMC 3980968. PMID 24120943.
Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang AH, et al. (July 2012). "Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human". Cell. 150 (2): 366–376. doi:10.1016/j.cell.2012.05.016. PMC 3402601. PMID 22796012.
Zhang Y, Xie C, Wang H, Foss RM, Clare M, George EV, et al. (August 2016). "Irisin exerts dual effects on browning and adipogenesis of human white adipocytes". American Journal of Physiology. Endocrinology and Metabolism. 311 (2): E530 – E541. doi:10.1152/ajpendo.00094.2016. PMID 27436609. S2CID 3433786.
Timmons JA, Baar K, Davidsen PK, Atherton PJ (August 2012). "Is irisin a human exercise gene?". Nature. 488 (7413): E9-10, discussion E10-1. Bibcode:2012Natur.488E...9T. doi:10.1038/nature11364. PMID 22932392. S2CID 4415979.
Albrecht E, Norheim F, Thiede B, Holen T, Ohashi T, Schering L, et al. (March 2015). "Irisin – a myth rather than an exercise-inducible myokine". Scientific Reports. 5: 8889. Bibcode:2015NatSR...5E8889A. doi:10.1038/srep08889. PMC 4352853. PMID 25749243.
Raschke S, Elsen M, Gassenhuber H, Sommerfeld M, Schwahn U, Brockmann B, et al. (2013). López-Lluch G (ed.). "Evidence against a beneficial effect of irisin in humans". PLOS ONE. 8 (9): e73680. Bibcode:2013PLoSO...873680R. doi:10.1371/journal.pone.0073680. PMC 3770677. PMID 24040023.
Maak S, Norheim F, Drevon CA, Erickson HP (July 2021). "Progress and Challenges in the Biology of FNDC5 and Irisin". Endocrine Reviews. 42 (4): 436–456. doi:10.1210/endrev/bnab003. PMC 8284618. PMID 33493316.
Islam MR, Valaris S, Young MF, Haley EB, Luo R, Bond SF, et al. (August 2021). "Exercise hormone irisin is a critical regulator of cognitive function". Nature Metabolism. 3 (8): 1058–1070. doi:10.1038/s42255-021-00438-z. PMC 10317538. PMID 34417591. S2CID 237254736.
Witmer NH, Linzer CR, and Boudreau RL (May 2024). "Fndc5 is translated from an upstream ATG start codon and cleaved to produce irisin myokine precursor protein in humans and mice". Cell Metabolism. 36 (5): 879–881. PMID 26278051.
Pedersen BK, Febbraio MA (October 2008). "Muscle as an endocrine organ: focus on muscle-derived interleukin-6". Physiological Reviews. 88 (4): 1379–1406. doi:10.1152/physrev.90100.2007. PMID 18923185.
Xiong Y, Wu Z, Zhang B, Wang C, Mao F, Liu X, et al. (May 2019). "Fndc5 loss-of-function attenuates exercise-induced browning of white adipose tissue in mice". FASEB Journal. 33 (5): 5876–5886. doi:10.1096/fj.201801754RR. PMID 30721625. S2CID 73444056.
Servick K (March 2015). "Biomedicine. Woes for 'exercise hormone'". Science. 347 (6228): 1299. doi:10.1126/science.347.6228.1299. PMID 25792309.
Colaianni G, Cuscito C, Mongelli T, Pignataro P, Buccoliero C, Liu P, et al. (September 2015). "The myokine irisin increases cortical bone mass". Proceedings of the National Academy of Sciences of the United States of America. 112 (39): 12157–12162. Bibcode:2015PNAS..11212157C. doi:10.1073/pnas.1516622112. PMC 4593131. PMID 26374841.
Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, et al. (December 2018). "Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors". Cell. 175 (7): 1756–1768.e17. doi:10.1530/ey.16.15.15. PMC 6298040. PMID 30550785.
Colaianni G, Sanesi L, Storlino G, Brunetti G, Colucci S, Grano M (May 2019). "Irisin and Bone: From Preclinical Studies to the Evaluation of Its Circulating Levels in Different Populations of Human Subjects". Cells. 8 (5): 451. doi:10.3390/cells8050451. PMC 6562988. PMID 31091695.
Huang L, Yan S, Luo L, Yang L (February 2019). "Irisin regulates the expression of BDNF and glycometabolism in diabetic rats". Molecular Medicine Reports. 19 (2): 1074–1082. doi:10.3892/mmr.2018.9743. PMC 6323232. PMID 30569121.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Erickson HP (October 2013). "Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?". Adipocyte. 2 (4): 289–293. doi:10.4161/adip.26082. PMC 3774709. PMID 24052909.
Farrash W, Brook M, Crossland H, Phillips BE, Cegielski J, Wilkinson DJ, et al. (June 2020). "Impacts of rat hindlimb Fndc5/irisin overexpression on muscle and adipose tissue metabolism". American Journal of Physiology. Endocrinology and Metabolism. 318 (6): E943 – E955. doi:10.1152/ajpendo.00034.2020. PMC 7311674. PMID 32369414.
Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. (January 2012). "A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis". Nature. 481 (7382): 463–468. Bibcode:2012Natur.481..463B. doi:10.1038/nature10777. PMC 3522098. PMID 22237023.
Jedrychowski MP, Wrann CD, Paulo JA, Gerber KK, Szpyt J, Robinson MM, et al. (October 2015). "Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry". Cell Metabolism. 22 (4): 734–740. doi:10.1016/j.cmet.2015.08.001. PMC 4802359. PMID 26278051.
Wrann CD, White JP, Salogiannnis J, Laznik-Bogoslavski D, Wu J, Ma D, et al. (November 2013). "Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway". Cell Metabolism. 18 (5): 649–659. doi:10.1016/j.cmet.2013.09.008. PMC 3980968. PMID 24120943.
Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang AH, et al. (July 2012). "Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human". Cell. 150 (2): 366–376. doi:10.1016/j.cell.2012.05.016. PMC 3402601. PMID 22796012.
Albrecht E, Norheim F, Thiede B, Holen T, Ohashi T, Schering L, et al. (March 2015). "Irisin – a myth rather than an exercise-inducible myokine". Scientific Reports. 5: 8889. Bibcode:2015NatSR...5E8889A. doi:10.1038/srep08889. PMC 4352853. PMID 25749243.
Raschke S, Elsen M, Gassenhuber H, Sommerfeld M, Schwahn U, Brockmann B, et al. (2013). López-Lluch G (ed.). "Evidence against a beneficial effect of irisin in humans". PLOS ONE. 8 (9): e73680. Bibcode:2013PLoSO...873680R. doi:10.1371/journal.pone.0073680. PMC 3770677. PMID 24040023.
Maak S, Norheim F, Drevon CA, Erickson HP (July 2021). "Progress and Challenges in the Biology of FNDC5 and Irisin". Endocrine Reviews. 42 (4): 436–456. doi:10.1210/endrev/bnab003. PMC 8284618. PMID 33493316.
Islam MR, Valaris S, Young MF, Haley EB, Luo R, Bond SF, et al. (August 2021). "Exercise hormone irisin is a critical regulator of cognitive function". Nature Metabolism. 3 (8): 1058–1070. doi:10.1038/s42255-021-00438-z. PMC 10317538. PMID 34417591. S2CID 237254736.
Colaianni G, Cuscito C, Mongelli T, Pignataro P, Buccoliero C, Liu P, et al. (September 2015). "The myokine irisin increases cortical bone mass". Proceedings of the National Academy of Sciences of the United States of America. 112 (39): 12157–12162. Bibcode:2015PNAS..11212157C. doi:10.1073/pnas.1516622112. PMC 4593131. PMID 26374841.
Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, et al. (December 2018). "Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors". Cell. 175 (7): 1756–1768.e17. doi:10.1530/ey.16.15.15. PMC 6298040. PMID 30550785.
Colaianni G, Sanesi L, Storlino G, Brunetti G, Colucci S, Grano M (May 2019). "Irisin and Bone: From Preclinical Studies to the Evaluation of Its Circulating Levels in Different Populations of Human Subjects". Cells. 8 (5): 451. doi:10.3390/cells8050451. PMC 6562988. PMID 31091695.
Huang L, Yan S, Luo L, Yang L (February 2019). "Irisin regulates the expression of BDNF and glycometabolism in diabetic rats". Molecular Medicine Reports. 19 (2): 1074–1082. doi:10.3892/mmr.2018.9743. PMC 6323232. PMID 30569121.

nytimes.com

well.blogs.nytimes.com

Reynolds G (January 11, 2012). "Exercise Hormone May Fight Obesity and Diabetes". Well. The New York Times. Retrieved January 12, 2012.

nytimes.com

Reynolds G (August 25, 2021). "How Exercise May Help Keep Our Memory Sharp". The New York Times. Retrieved September 21, 2021.

scientificamerican.com

blogs.scientificamerican.com

Courage KH. "Newly Discovered Hormone Boosts Effects of Exercise, Could Help Fend Off Diabetes". Observations. Scientific American. Retrieved January 12, 2012.

semanticscholar.org

api.semanticscholar.org

Ferrer-Martínez A, Ruiz-Lozano P, Chien KR (June 2002). "Mouse PeP: a novel peroxisomal protein linked to myoblast differentiation and development". Developmental Dynamics. 224 (2): 154–167. doi:10.1002/dvdy.10099. PMID 12112469. S2CID 42445530.
Zhang Y, Xie C, Wang H, Foss RM, Clare M, George EV, et al. (August 2016). "Irisin exerts dual effects on browning and adipogenesis of human white adipocytes". American Journal of Physiology. Endocrinology and Metabolism. 311 (2): E530 – E541. doi:10.1152/ajpendo.00094.2016. PMID 27436609. S2CID 3433786.
Timmons JA, Baar K, Davidsen PK, Atherton PJ (August 2012). "Is irisin a human exercise gene?". Nature. 488 (7413): E9-10, discussion E10-1. Bibcode:2012Natur.488E...9T. doi:10.1038/nature11364. PMID 22932392. S2CID 4415979.
Islam MR, Valaris S, Young MF, Haley EB, Luo R, Bond SF, et al. (August 2021). "Exercise hormone irisin is a critical regulator of cognitive function". Nature Metabolism. 3 (8): 1058–1070. doi:10.1038/s42255-021-00438-z. PMC 10317538. PMID 34417591. S2CID 237254736.
Xiong Y, Wu Z, Zhang B, Wang C, Mao F, Liu X, et al. (May 2019). "Fndc5 loss-of-function attenuates exercise-induced browning of white adipose tissue in mice". FASEB Journal. 33 (5): 5876–5886. doi:10.1096/fj.201801754RR. PMID 30721625. S2CID 73444056.

time.com

Park A (April 8, 2009). "Brown Fat: A Fat That Helps You Lose Weight?". Health & Science. Time. Archived from the original on April 11, 2009. Retrieved January 12, 2012.

web.archive.org

Park A (April 8, 2009). "Brown Fat: A Fat That Helps You Lose Weight?". Health & Science. Time. Archived from the original on April 11, 2009. Retrieved January 12, 2012.