Fibrodysplasia ossificans progressiva (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Fibrodysplasia ossificans progressiva" in English language version.

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37nih.gov

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26doi.org

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8worldcat.org

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aaos.org (Global: 7,491^st place; English: 4,817^th place)

orthoinfo.aaos.org

American Academy of Orthopaedic Surgeons (May 2006). "Fibrodysplasia Ossificans Progressiva (FOP)". orthoinfo.aaos.org. Archived from the original on 21 June 2012. Retrieved 7 October 2011.

businesswire.com (Global: 615^th place; English: 407^th place)

"Health Canada Approves Ipsen's Sohonos (palovarotene capsules) as the First Approved Treatment for Fibrodysplasia Ossificans Progressiva" (Press release). Ipsen. 24 January 2022. Archived from the original on 29 May 2022. Retrieved 28 May 2022 – via Business Wire.
"La Jolla Pharmaceutical Company Receives Orphan Drug Designation for Two Novel Compounds for Fibrodysplasia Ossificans Progressiva" (Press release). La Jolla Pharmaceutical Company. 18 August 2015.

clementiapharma.com (Global: low place; English: low place)

"Pipeline". www.clementiapharma.com. Archived from the original on 29 September 2015. Retrieved 22 November 2015.

d3n8a8pro7vhmx.cloudfront.net (Global: low place; English: low place)

"The Medical Management of Fibrodysplasia Ossificans Progressiva: Current Treatment Considerations" (PDF). International Fibrodysplasia Ossificans Progressiva Association. January 2020.

doi.org (Global: 2^nd place; English: 2^nd place)

Verma, Amit Kumar; Aga, Pallavi; Singh, Shailesh Kumar; Singh, Ragini (2012). "The stone man disease: fibrodysplasia ossificans progressiva: imaging revisited". BMJ Case Reports. 2012: bcr2012006422. doi:10.1136/bcr-2012-006422. PMC 4543882. PMID 22843760.
Kaplan, Frederick S.; Shen, Qi; Lounev, Vitali; Seemann, Petra; Groppe, Jay; Katagiri, Takenobu; Pignolo, Robert J.; Shore, Eileen M. (2008). "Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)". Journal of Bone and Mineral Metabolism. 26 (6): 521–530. doi:10.1007/s00774-008-0879-8. PMC 3620015. PMID 18979151.
Martelli, Anderson; Santos, Arnaldo Rodrigues (3 July 2014). "Cellular and morphological aspects of fibrodysplasia ossificans progressiva: Lessons of formation, repair, and bone bioengineering". Organogenesis. 10 (3): 303–311. doi:10.4161/org.29206. PMC 4750545. PMID 25482313.
Peltier, Leonard F. (January 1998). "A Case of Extraordinary Exostoses on the Back of a Boy". Clinical Orthopaedics and Related Research. 346: 5–6. doi:10.1097/00003086-199801000-00002. ISSN 0009-921X.
Kaplan, F. S. (2013). The skeleton in the closet. Gene, 528(1), 7–11. https://doi.org/10.1016/j.gene.2013.06.022
Shore, Eileen M; Xu, Meiqi; Feldman, George J; Fenstermacher, David A; Cho, Tae-Joon; Choi, In Ho; Connor, J Michael; Delai, Patricia; Glaser, David L; LeMerrer, Martine; Morhart, Rolf; Rogers, John G; Smith, Roger; Triffitt, James T; Urtizberea, J Andoni; Zasloff, Michael; Brown, Matthew A; Kaplan, Frederick S (May 2006). "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva". Nature Genetics. 38 (5): 525–527. doi:10.1038/ng1783. PMID 16642017. S2CID 41579747.
Hatsell, Sarah J.; Idone, Vincent; Wolken, Dana M. Alessi; Huang, Lily; Kim, Hyon J.; Wang, Lili; Wen, Xialing; Nannuru, Kalyan C.; Jimenez, Johanna; Xie, Liqin; Das, Nanditha; Makhoul, Genevieve; Chernomorsky, Rostislav; D'Ambrosio, David; Corpina, Richard A.; Schoenherr, Christopher J.; Feeley, Kieran; Yu, Paul B.; Yancopoulos, George D.; Murphy, Andrew J.; Economides, Aris N. (2 September 2015). "ACVR1 R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A". Science Translational Medicine. 7 (303): 303ra137. doi:10.1126/scitranslmed.aac4358. PMC 6164166. PMID 26333933.
van Dinther, Maarten; Visser, Nils; de Gorter, David JJ; Doorn, Joyce; Goumans, Marie-José; de Boer, Jan; ten Dijke, Peter (23 November 2009). "ALK2 R206H Mutation Linked to Fibrodysplasia Ossificans Progressiva Confers Constitutive Activity to the BMP Type I Receptor and Sensitizes Mesenchymal Cells to BMP-Induced Osteoblast Differentiation and Bone Formation". Journal of Bone and Mineral Research. 25 (6): 091211115834058–35. doi:10.1359/jbmr.091110. PMID 19929436. S2CID 207269687.
Lin, Shuxian; Svoboda, Kathy K. H.; Feng, Jian Q.; Jiang, Xinquan (5 April 2016). "The biological function of type I receptors of bone morphogenetic protein in bone". Bone Research. 4 (1): 16005. doi:10.1038/boneres.2016.5. ISSN 2095-6231. PMC 4820739. PMID 27088043.
Shore, Eileen M.; Kaplan, Frederick S. (2008). "Insights from a Rare Genetic Disorder of Extra-Skeletal Bone Formation, Fibrodysplasia Ossificans Progressiva (FOP)". Bone. 43 (3): 427–443. doi:10.1016/j.bone.2008.05.013. PMC 2601573. PMID 18590993.
Kaplan, Frederick S.; Le Merrer, Martine; Glaser, David L.; Pignolo, Robert J.; Goldsby, Robert E.; Kitterman, Joseph A.; Groppe, Jay; Shore, Eileen M. (March 2008). "Fibrodysplasia ossificans progressiva". Best Practice & Research Clinical Rheumatology. 22 (1): 191–205. doi:10.1016/j.berh.2007.11.007. PMC 2424023. PMID 18328989.
Petrie, KA; Lee, WH; Bullock, AN; Pointon, JJ; Smith, R; Russell, RG; Brown, MA; Wordsworth, BP; Triffitt, JT (2009). "Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients". PLOS ONE. 4 (3) e5005. Bibcode:2009PLoSO...4.5005P. doi:10.1371/journal.pone.0005005. PMC 2658887. PMID 19330033.
Obamuyide, HA; Ogunlade, SO (March 2015). "A Tumour for which Surgery will do more harm than good: A Case Report of Fibrodysplasia Ossificans Progressiva". The Nigerian Postgraduate Medical Journal. 22 (1): 83–8. doi:10.4103/1117-1936.163373. PMID 25875418. S2CID 33239264. ProQuest 1850178336.
Saleh, Mohammed; Commandeur, Joost; Bocciardi, Renata; Kinabo, Grace; Hamel, Ben (2015). "Fibrodysplasia ossificans progressiva with minor unilateral hallux anomaly in a sporadic case from Northern Tanzania with the common ACVR1c.617G>A mutation". Pan African Medical Journal. 22: 299. doi:10.11604/pamj.2015.22.299.8032. PMC 4769042. PMID 26966495.
Bauer, Adam H.; Bonham, Jeff; Gutierrez, Luis; Hsiao, Edward C.; Motamedi, Daria (August 2018). "Fibrodysplasia ossificans progressiva: a current review of imaging findings". Skeletal Radiology. 47 (8): 1043–1050. doi:10.1007/s00256-018-2889-5. ISSN 0364-2348.
González Trotter, Dinko; McGinniss, Jennifer; Mohammadi, Kusha; Musser, Bret J.; Herman, Gary A.; Mellis, Scott; Economides, Aris N. (January 2025). "Comparison of PET/CT versus CT only in the assessment of new heterotopic ossification bone lesions in patients with fibrodysplasia ossificans progressiva". Bone. 190 117280. doi:10.1016/j.bone.2024.117280.
Yamin, Ghiam; Daghighi, Shadi; Mafee, Mahmood (31 May 2021). "Fibrodysplasia ossificans progressiva (FOP) presenting as a rapidly growing non-calcified neck mass". Journal of Radiology Case Reports. 15 (5): 10–16. doi:10.3941/jrcr.v15i5.4103. ISSN 1943-0922. PMC 8253151. PMID 34276874.
Newton, M.C.; Allen, P.W.; Ryan, D.C. (February 1990). "Fibrodysplasia Ossificans Progressiva". British Journal of Anaesthesia. 64 (2): 246–250. doi:10.1093/bja/64.2.246. PMID 2317429.
Lanchoney, TF; Cohen, RB; Rocke, DM; Zasloff, MA; Kaplan, FS (May 1995). "Permanent heterotopic ossification at the injection site after diphtheria-tetanus-pertussis immunizations in children who have fibrodysplasia ossificans progressiva". J Pediatr. 126 (5 Pt 1): 762–4. doi:10.1016/s0022-3476(95)70408-6. PMID 7752003.
Kaplan, Frederick S.; Le Merrer, Martine; Glaser, David L.; Pignolo, Robert J.; Goldsby, Robert; Kitterman, Joseph A.; Groppe, Jay; Shore, Eileen M. (March 2008). "Fibrodysplasia ossificans progressiva". Best Practice & Research. Clinical Rheumatology. 22 (1): 191–205. doi:10.1016/j.berh.2007.11.007. ISSN 1521-6942. PMC 2424023. PMID 18328989.
Kitoh, Hiroshi; Achiwa, Masataka; Kaneko, Hiroshi; Mishima, Kenichi; Matsushita, Masaki; Kadono, Izumi; Horowitz, John D; Sallustio, Benedetta C; Ohno, Kinji; Ishiguro, Naoki (2013). "Perhexiline maleate in the treatment of fibrodysplasia ossificans progressiva: an open-labeled clinical trial". Orphanet Journal of Rare Diseases. 8 (1): 163. doi:10.1186/1750-1172-8-163. PMC 4015865. PMID 24131551.
Pignolo, Robert J.; Hsiao, Edward C.; Al Mukaddam, Mona; Baujat, Geneviève; Berglund, Staffan K.; Brown, Matthew A.; Cheung, Angela M.; De Cunto, Carmen; Delai, Patricia; Haga, Nobuhiko; Kannu, Peter; Keen, Richard; Le Quan Sang, Kim‐Hanh; Mancilla, Edna E.; Marino, Rose (March 2023). "Reduction of New Heterotopic Ossification (HO) in the Open‐Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP)". Journal of Bone and Mineral Research. 38 (3): 381–394. doi:10.1002/jbmr.4762. ISSN 0884-0431.
Maruyama, Rika; Nguyen, Quynh; Roshmi, Rohini Roy; Touznik, Aleksander; Yokota, Toshifumi (June 2022). "Allele-Selective LNA Gapmers for the Treatment of Fibrodysplasia Ossificans Progressiva Knock Down the Pathogenic ACVR1R206H Transcript and Inhibit Osteogenic Differentiation". Nucleic Acid Therapeutics. 32 (3): 185–193. doi:10.1089/nat.2021.0009. ISSN 2159-3345. PMID 35085461.
J. W. Lowery; V. Rosen (2012). "Allele-Specific RNA Interference in FOP Silencing the FOP gene". Gene Therapy. 19 (7): 701–702. doi:10.1038/gt.2011.190. PMID 22130446. S2CID 24990800.
Lees-Shepard, John B.; Yamamoto, Masakazu; Biswas, Arpita A.; Stoessel, Sean J.; Nicholas, Sarah-Anne E.; Cogswell, Cathy A.; Devarakonda, Parvathi M.; Schneider, Michael J.; Cummins, Samantha M.; Legendre, Nicholas P.; Yamamoto, Shoko; Kaartinen, Vesa; Hunter, Jeffrey W.; Goldhamer, David J. (December 2018). "Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva". Nature Communications. 9 (1): 471. Bibcode:2018NatCo...9..471L. doi:10.1038/s41467-018-02872-2. PMC 5797136. PMID 29396429.
Williams, Eleanor; Bagarova, Jana; Kerr, Georgina; Xia, Dong-Dong; Place, Elsie S.; Dey, Devaveena; Shen, Yue; Bocobo, Geoffrey A.; Mohedas, Agustin H.; Huang, Xiuli; Sanderson, Philip E. (2021). "Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva". JCI Insight. 6 (8) e95042. doi:10.1172/jci.insight.95042. ISSN 2379-3708. PMC 8119212. PMID 33705358.

elsevier.com (Global: 610^th place; English: 704^th place)

linkinghub.elsevier.com

González Trotter, Dinko; McGinniss, Jennifer; Mohammadi, Kusha; Musser, Bret J.; Herman, Gary A.; Mellis, Scott; Economides, Aris N. (January 2025). "Comparison of PET/CT versus CT only in the assessment of new heterotopic ossification bone lesions in patients with fibrodysplasia ossificans progressiva". Bone. 190 117280. doi:10.1016/j.bone.2024.117280.

fda.gov (Global: 447^th place; English: 338^th place)

Research, Center for Drug Evaluation and (17 August 2023). "FDA approves first treatment for Fibrodysplasia Ossificans Progressiva". FDA. Archived from the original on 18 August 2023.

harvard.edu (Global: 18^th place; English: 17^th place)

ui.adsabs.harvard.edu

Petrie, KA; Lee, WH; Bullock, AN; Pointon, JJ; Smith, R; Russell, RG; Brown, MA; Wordsworth, BP; Triffitt, JT (2009). "Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients". PLOS ONE. 4 (3) e5005. Bibcode:2009PLoSO...4.5005P. doi:10.1371/journal.pone.0005005. PMC 2658887. PMID 19330033.
Lees-Shepard, John B.; Yamamoto, Masakazu; Biswas, Arpita A.; Stoessel, Sean J.; Nicholas, Sarah-Anne E.; Cogswell, Cathy A.; Devarakonda, Parvathi M.; Schneider, Michael J.; Cummins, Samantha M.; Legendre, Nicholas P.; Yamamoto, Shoko; Kaartinen, Vesa; Hunter, Jeffrey W.; Goldhamer, David J. (December 2018). "Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva". Nature Communications. 9 (1): 471. Bibcode:2018NatCo...9..471L. doi:10.1038/s41467-018-02872-2. PMC 5797136. PMID 29396429.

ifopa.org (Global: low place; English: low place)

"Regeneron Shares Updates on its Ongoing FOP Research Program". International Fibrodysplasia Ossificans Progressiva Association. 9 March 2017.

medlineplus.gov (Global: 1,581^st place; English: 1,299^th place)

"AVCR1", Genetics Home Reference, U.S. National Library of Medicine, August 2007. Accessed February 18, 2014.
"Fibrodysplasia ossificans progressiva", Genetics Home Reference, U.S. National Library of Medicine, August 2007. Accessed February 18, 2014.
"Fibrodysplasia ossificans progressiva: MedlinePlus Genetics". medlineplus.gov. Retrieved 31 December 2022.
"Fibrodysplasia ossificans progressiva". Lister Hill National Center for Biomedical Communications. Retrieved 12 December 2013.

merriam-webster.com (Global: 209^th place; English: 191^st place)

"Medical Definition of fibrodysplasia ossificans progressiva". www.merriam-webster.com. Retrieved 8 May 2022.

muttermuseum.org (Global: low place; English: low place)

"Mütter Museum Reveals New Exhibit: Philadelphia Woman's Skeleton With Rare Bone Disease". Mütter Museum. 5 March 2019. Archived from the original on 28 August 2021. Retrieved 7 March 2020.

nationalgeographic.com (Global: 344^th place; English: 296^th place)

Pinkowski, Jen (1 March 2019). "Here's what happens when your body tissues turn to bone". National Geographic. Archived from the original on 3 March 2019.

nbcnews.com (Global: 137^th place; English: 101^st place)

"AP: Scientists solve rare bone disease mystery". NBC News. 24 April 2006. Retrieved 8 May 2022.

nih.gov (Global: 4^th place; English: 4^th place)

pubmed.ncbi.nlm.nih.gov

Verma, Amit Kumar; Aga, Pallavi; Singh, Shailesh Kumar; Singh, Ragini (2012). "The stone man disease: fibrodysplasia ossificans progressiva: imaging revisited". BMJ Case Reports. 2012: bcr2012006422. doi:10.1136/bcr-2012-006422. PMC 4543882. PMID 22843760.
Kaplan, Frederick S.; Shen, Qi; Lounev, Vitali; Seemann, Petra; Groppe, Jay; Katagiri, Takenobu; Pignolo, Robert J.; Shore, Eileen M. (2008). "Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)". Journal of Bone and Mineral Metabolism. 26 (6): 521–530. doi:10.1007/s00774-008-0879-8. PMC 3620015. PMID 18979151.
Martelli, Anderson; Santos, Arnaldo Rodrigues (3 July 2014). "Cellular and morphological aspects of fibrodysplasia ossificans progressiva: Lessons of formation, repair, and bone bioengineering". Organogenesis. 10 (3): 303–311. doi:10.4161/org.29206. PMC 4750545. PMID 25482313.
Shore, Eileen M; Xu, Meiqi; Feldman, George J; Fenstermacher, David A; Cho, Tae-Joon; Choi, In Ho; Connor, J Michael; Delai, Patricia; Glaser, David L; LeMerrer, Martine; Morhart, Rolf; Rogers, John G; Smith, Roger; Triffitt, James T; Urtizberea, J Andoni; Zasloff, Michael; Brown, Matthew A; Kaplan, Frederick S (May 2006). "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva". Nature Genetics. 38 (5): 525–527. doi:10.1038/ng1783. PMID 16642017. S2CID 41579747.
Hatsell, Sarah J.; Idone, Vincent; Wolken, Dana M. Alessi; Huang, Lily; Kim, Hyon J.; Wang, Lili; Wen, Xialing; Nannuru, Kalyan C.; Jimenez, Johanna; Xie, Liqin; Das, Nanditha; Makhoul, Genevieve; Chernomorsky, Rostislav; D'Ambrosio, David; Corpina, Richard A.; Schoenherr, Christopher J.; Feeley, Kieran; Yu, Paul B.; Yancopoulos, George D.; Murphy, Andrew J.; Economides, Aris N. (2 September 2015). "ACVR1 R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A". Science Translational Medicine. 7 (303): 303ra137. doi:10.1126/scitranslmed.aac4358. PMC 6164166. PMID 26333933.
van Dinther, Maarten; Visser, Nils; de Gorter, David JJ; Doorn, Joyce; Goumans, Marie-José; de Boer, Jan; ten Dijke, Peter (23 November 2009). "ALK2 R206H Mutation Linked to Fibrodysplasia Ossificans Progressiva Confers Constitutive Activity to the BMP Type I Receptor and Sensitizes Mesenchymal Cells to BMP-Induced Osteoblast Differentiation and Bone Formation". Journal of Bone and Mineral Research. 25 (6): 091211115834058–35. doi:10.1359/jbmr.091110. PMID 19929436. S2CID 207269687.
Lin, Shuxian; Svoboda, Kathy K. H.; Feng, Jian Q.; Jiang, Xinquan (5 April 2016). "The biological function of type I receptors of bone morphogenetic protein in bone". Bone Research. 4 (1): 16005. doi:10.1038/boneres.2016.5. ISSN 2095-6231. PMC 4820739. PMID 27088043.
Shore, Eileen M.; Kaplan, Frederick S. (2008). "Insights from a Rare Genetic Disorder of Extra-Skeletal Bone Formation, Fibrodysplasia Ossificans Progressiva (FOP)". Bone. 43 (3): 427–443. doi:10.1016/j.bone.2008.05.013. PMC 2601573. PMID 18590993.
Kaplan, Frederick S.; Le Merrer, Martine; Glaser, David L.; Pignolo, Robert J.; Goldsby, Robert E.; Kitterman, Joseph A.; Groppe, Jay; Shore, Eileen M. (March 2008). "Fibrodysplasia ossificans progressiva". Best Practice & Research Clinical Rheumatology. 22 (1): 191–205. doi:10.1016/j.berh.2007.11.007. PMC 2424023. PMID 18328989.
Petrie, KA; Lee, WH; Bullock, AN; Pointon, JJ; Smith, R; Russell, RG; Brown, MA; Wordsworth, BP; Triffitt, JT (2009). "Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients". PLOS ONE. 4 (3) e5005. Bibcode:2009PLoSO...4.5005P. doi:10.1371/journal.pone.0005005. PMC 2658887. PMID 19330033.
Obamuyide, HA; Ogunlade, SO (March 2015). "A Tumour for which Surgery will do more harm than good: A Case Report of Fibrodysplasia Ossificans Progressiva". The Nigerian Postgraduate Medical Journal. 22 (1): 83–8. doi:10.4103/1117-1936.163373. PMID 25875418. S2CID 33239264. ProQuest 1850178336.
Saleh, Mohammed; Commandeur, Joost; Bocciardi, Renata; Kinabo, Grace; Hamel, Ben (2015). "Fibrodysplasia ossificans progressiva with minor unilateral hallux anomaly in a sporadic case from Northern Tanzania with the common ACVR1c.617G>A mutation". Pan African Medical Journal. 22: 299. doi:10.11604/pamj.2015.22.299.8032. PMC 4769042. PMID 26966495.
Akesson, Lauren S.; Savarirayan, Ravi (1993), Adam, Margaret P.; Feldman, Jerry; Mirzaa, Ghayda M.; Pagon, Roberta A. (eds.), "Fibrodysplasia Ossificans Progressiva", GeneReviews, Seattle (WA): University of Washington, Seattle, PMID 32525643, retrieved 25 September 2025
Yamin, Ghiam; Daghighi, Shadi; Mafee, Mahmood (31 May 2021). "Fibrodysplasia ossificans progressiva (FOP) presenting as a rapidly growing non-calcified neck mass". Journal of Radiology Case Reports. 15 (5): 10–16. doi:10.3941/jrcr.v15i5.4103. ISSN 1943-0922. PMC 8253151. PMID 34276874.
Newton, M.C.; Allen, P.W.; Ryan, D.C. (February 1990). "Fibrodysplasia Ossificans Progressiva". British Journal of Anaesthesia. 64 (2): 246–250. doi:10.1093/bja/64.2.246. PMID 2317429.
Lanchoney, TF; Cohen, RB; Rocke, DM; Zasloff, MA; Kaplan, FS (May 1995). "Permanent heterotopic ossification at the injection site after diphtheria-tetanus-pertussis immunizations in children who have fibrodysplasia ossificans progressiva". J Pediatr. 126 (5 Pt 1): 762–4. doi:10.1016/s0022-3476(95)70408-6. PMID 7752003.
Kaplan, Frederick S.; Le Merrer, Martine; Glaser, David L.; Pignolo, Robert J.; Goldsby, Robert; Kitterman, Joseph A.; Groppe, Jay; Shore, Eileen M. (March 2008). "Fibrodysplasia ossificans progressiva". Best Practice & Research. Clinical Rheumatology. 22 (1): 191–205. doi:10.1016/j.berh.2007.11.007. ISSN 1521-6942. PMC 2424023. PMID 18328989.
Kitoh, Hiroshi; Achiwa, Masataka; Kaneko, Hiroshi; Mishima, Kenichi; Matsushita, Masaki; Kadono, Izumi; Horowitz, John D; Sallustio, Benedetta C; Ohno, Kinji; Ishiguro, Naoki (2013). "Perhexiline maleate in the treatment of fibrodysplasia ossificans progressiva: an open-labeled clinical trial". Orphanet Journal of Rare Diseases. 8 (1): 163. doi:10.1186/1750-1172-8-163. PMC 4015865. PMID 24131551.
Maruyama, Rika; Nguyen, Quynh; Roshmi, Rohini Roy; Touznik, Aleksander; Yokota, Toshifumi (June 2022). "Allele-Selective LNA Gapmers for the Treatment of Fibrodysplasia Ossificans Progressiva Knock Down the Pathogenic ACVR1R206H Transcript and Inhibit Osteogenic Differentiation". Nucleic Acid Therapeutics. 32 (3): 185–193. doi:10.1089/nat.2021.0009. ISSN 2159-3345. PMID 35085461.
J. W. Lowery; V. Rosen (2012). "Allele-Specific RNA Interference in FOP Silencing the FOP gene". Gene Therapy. 19 (7): 701–702. doi:10.1038/gt.2011.190. PMID 22130446. S2CID 24990800.
Lees-Shepard, John B.; Yamamoto, Masakazu; Biswas, Arpita A.; Stoessel, Sean J.; Nicholas, Sarah-Anne E.; Cogswell, Cathy A.; Devarakonda, Parvathi M.; Schneider, Michael J.; Cummins, Samantha M.; Legendre, Nicholas P.; Yamamoto, Shoko; Kaartinen, Vesa; Hunter, Jeffrey W.; Goldhamer, David J. (December 2018). "Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva". Nature Communications. 9 (1): 471. Bibcode:2018NatCo...9..471L. doi:10.1038/s41467-018-02872-2. PMC 5797136. PMID 29396429.
Williams, Eleanor; Bagarova, Jana; Kerr, Georgina; Xia, Dong-Dong; Place, Elsie S.; Dey, Devaveena; Shen, Yue; Bocobo, Geoffrey A.; Mohedas, Agustin H.; Huang, Xiuli; Sanderson, Philip E. (2021). "Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva". JCI Insight. 6 (8) e95042. doi:10.1172/jci.insight.95042. ISSN 2379-3708. PMC 8119212. PMID 33705358.

ncbi.nlm.nih.gov

Verma, Amit Kumar; Aga, Pallavi; Singh, Shailesh Kumar; Singh, Ragini (2012). "The stone man disease: fibrodysplasia ossificans progressiva: imaging revisited". BMJ Case Reports. 2012: bcr2012006422. doi:10.1136/bcr-2012-006422. PMC 4543882. PMID 22843760.
Kaplan, Frederick S.; Shen, Qi; Lounev, Vitali; Seemann, Petra; Groppe, Jay; Katagiri, Takenobu; Pignolo, Robert J.; Shore, Eileen M. (2008). "Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)". Journal of Bone and Mineral Metabolism. 26 (6): 521–530. doi:10.1007/s00774-008-0879-8. PMC 3620015. PMID 18979151.
Martelli, Anderson; Santos, Arnaldo Rodrigues (3 July 2014). "Cellular and morphological aspects of fibrodysplasia ossificans progressiva: Lessons of formation, repair, and bone bioengineering". Organogenesis. 10 (3): 303–311. doi:10.4161/org.29206. PMC 4750545. PMID 25482313.
Hatsell, Sarah J.; Idone, Vincent; Wolken, Dana M. Alessi; Huang, Lily; Kim, Hyon J.; Wang, Lili; Wen, Xialing; Nannuru, Kalyan C.; Jimenez, Johanna; Xie, Liqin; Das, Nanditha; Makhoul, Genevieve; Chernomorsky, Rostislav; D'Ambrosio, David; Corpina, Richard A.; Schoenherr, Christopher J.; Feeley, Kieran; Yu, Paul B.; Yancopoulos, George D.; Murphy, Andrew J.; Economides, Aris N. (2 September 2015). "ACVR1 R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A". Science Translational Medicine. 7 (303): 303ra137. doi:10.1126/scitranslmed.aac4358. PMC 6164166. PMID 26333933.
Lin, Shuxian; Svoboda, Kathy K. H.; Feng, Jian Q.; Jiang, Xinquan (5 April 2016). "The biological function of type I receptors of bone morphogenetic protein in bone". Bone Research. 4 (1): 16005. doi:10.1038/boneres.2016.5. ISSN 2095-6231. PMC 4820739. PMID 27088043.
Shore, Eileen M.; Kaplan, Frederick S. (2008). "Insights from a Rare Genetic Disorder of Extra-Skeletal Bone Formation, Fibrodysplasia Ossificans Progressiva (FOP)". Bone. 43 (3): 427–443. doi:10.1016/j.bone.2008.05.013. PMC 2601573. PMID 18590993.
Kaplan, Frederick S.; Le Merrer, Martine; Glaser, David L.; Pignolo, Robert J.; Goldsby, Robert E.; Kitterman, Joseph A.; Groppe, Jay; Shore, Eileen M. (March 2008). "Fibrodysplasia ossificans progressiva". Best Practice & Research Clinical Rheumatology. 22 (1): 191–205. doi:10.1016/j.berh.2007.11.007. PMC 2424023. PMID 18328989.
Petrie, KA; Lee, WH; Bullock, AN; Pointon, JJ; Smith, R; Russell, RG; Brown, MA; Wordsworth, BP; Triffitt, JT (2009). "Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients". PLOS ONE. 4 (3) e5005. Bibcode:2009PLoSO...4.5005P. doi:10.1371/journal.pone.0005005. PMC 2658887. PMID 19330033.
Saleh, Mohammed; Commandeur, Joost; Bocciardi, Renata; Kinabo, Grace; Hamel, Ben (2015). "Fibrodysplasia ossificans progressiva with minor unilateral hallux anomaly in a sporadic case from Northern Tanzania with the common ACVR1c.617G>A mutation". Pan African Medical Journal. 22: 299. doi:10.11604/pamj.2015.22.299.8032. PMC 4769042. PMID 26966495.
Akesson, Lauren S.; Savarirayan, Ravi (1993), Adam, Margaret P.; Feldman, Jerry; Mirzaa, Ghayda M.; Pagon, Roberta A. (eds.), "Fibrodysplasia Ossificans Progressiva", GeneReviews, Seattle (WA): University of Washington, Seattle, PMID 32525643, retrieved 25 September 2025
Yamin, Ghiam; Daghighi, Shadi; Mafee, Mahmood (31 May 2021). "Fibrodysplasia ossificans progressiva (FOP) presenting as a rapidly growing non-calcified neck mass". Journal of Radiology Case Reports. 15 (5): 10–16. doi:10.3941/jrcr.v15i5.4103. ISSN 1943-0922. PMC 8253151. PMID 34276874.
Kaplan, Frederick S.; Le Merrer, Martine; Glaser, David L.; Pignolo, Robert J.; Goldsby, Robert; Kitterman, Joseph A.; Groppe, Jay; Shore, Eileen M. (March 2008). "Fibrodysplasia ossificans progressiva". Best Practice & Research. Clinical Rheumatology. 22 (1): 191–205. doi:10.1016/j.berh.2007.11.007. ISSN 1521-6942. PMC 2424023. PMID 18328989.
Kitoh, Hiroshi; Achiwa, Masataka; Kaneko, Hiroshi; Mishima, Kenichi; Matsushita, Masaki; Kadono, Izumi; Horowitz, John D; Sallustio, Benedetta C; Ohno, Kinji; Ishiguro, Naoki (2013). "Perhexiline maleate in the treatment of fibrodysplasia ossificans progressiva: an open-labeled clinical trial". Orphanet Journal of Rare Diseases. 8 (1): 163. doi:10.1186/1750-1172-8-163. PMC 4015865. PMID 24131551.
Lees-Shepard, John B.; Yamamoto, Masakazu; Biswas, Arpita A.; Stoessel, Sean J.; Nicholas, Sarah-Anne E.; Cogswell, Cathy A.; Devarakonda, Parvathi M.; Schneider, Michael J.; Cummins, Samantha M.; Legendre, Nicholas P.; Yamamoto, Shoko; Kaartinen, Vesa; Hunter, Jeffrey W.; Goldhamer, David J. (December 2018). "Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva". Nature Communications. 9 (1): 471. Bibcode:2018NatCo...9..471L. doi:10.1038/s41467-018-02872-2. PMC 5797136. PMID 29396429.
Williams, Eleanor; Bagarova, Jana; Kerr, Georgina; Xia, Dong-Dong; Place, Elsie S.; Dey, Devaveena; Shen, Yue; Bocobo, Geoffrey A.; Mohedas, Agustin H.; Huang, Xiuli; Sanderson, Philip E. (2021). "Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva". JCI Insight. 6 (8) e95042. doi:10.1172/jci.insight.95042. ISSN 2379-3708. PMC 8119212. PMID 33705358.

oup.com (Global: 485^th place; English: 440^th place)

academic.oup.com

Pignolo, Robert J.; Hsiao, Edward C.; Al Mukaddam, Mona; Baujat, Geneviève; Berglund, Staffan K.; Brown, Matthew A.; Cheung, Angela M.; De Cunto, Carmen; Delai, Patricia; Haga, Nobuhiko; Kannu, Peter; Keen, Richard; Le Quan Sang, Kim‐Hanh; Mancilla, Edna E.; Marino, Rose (March 2023). "Reduction of New Heterotopic Ossification (HO) in the Open‐Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP)". Journal of Bone and Mineral Research. 38 (3): 381–394. doi:10.1002/jbmr.4762. ISSN 0884-0431.

pennmedicine.org (Global: low place; English: low place)

"An FOP Timeline". Penn Medicine. University of Pennsylvania. Retrieved 8 May 2022.

philly.com (Global: 664^th place; English: 398^th place)

McCullough, Marie (28 February 2019). "New Mutter Museum exhibit grants final wish for woman who turned to bone". The Philadelphia Inquirer. Retrieved 28 February 2019.

prnewswire.com (Global: 406^th place; English: 258^th place)

"Clementia Pharmaceuticals Expands Ongoing Phase 2 Study to Include Children with Fibrodysplasia Ossificans Progressiva (FOP)" (Press release). Clementia Pharmaceuticals. 25 August 2015.

proquest.com (Global: 206^th place; English: 124^th place)

Obamuyide, HA; Ogunlade, SO (March 2015). "A Tumour for which Surgery will do more harm than good: A Case Report of Fibrodysplasia Ossificans Progressiva". The Nigerian Postgraduate Medical Journal. 22 (1): 83–8. doi:10.4103/1117-1936.163373. PMID 25875418. S2CID 33239264. ProQuest 1850178336.

rarediseases.org (Global: 5,181^st place; English: 3,260^th place)

"Dr. Frederick Kaplan, M.D. 2017 Rare Impact Award Honoree". National Organization for Rare Disorders. 15 March 2017. Retrieved 8 May 2022.

sciencedaily.com (Global: 993^rd place; English: 920^th place)

"Penn Researchers Discover Gene That Creates Second Skeleton" (Press release). University of Pennsylvania School of Medicine. 23 April 2006.

semanticscholar.org (Global: 11^th place; English: 8^th place)

api.semanticscholar.org

Shore, Eileen M; Xu, Meiqi; Feldman, George J; Fenstermacher, David A; Cho, Tae-Joon; Choi, In Ho; Connor, J Michael; Delai, Patricia; Glaser, David L; LeMerrer, Martine; Morhart, Rolf; Rogers, John G; Smith, Roger; Triffitt, James T; Urtizberea, J Andoni; Zasloff, Michael; Brown, Matthew A; Kaplan, Frederick S (May 2006). "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva". Nature Genetics. 38 (5): 525–527. doi:10.1038/ng1783. PMID 16642017. S2CID 41579747.
van Dinther, Maarten; Visser, Nils; de Gorter, David JJ; Doorn, Joyce; Goumans, Marie-José; de Boer, Jan; ten Dijke, Peter (23 November 2009). "ALK2 R206H Mutation Linked to Fibrodysplasia Ossificans Progressiva Confers Constitutive Activity to the BMP Type I Receptor and Sensitizes Mesenchymal Cells to BMP-Induced Osteoblast Differentiation and Bone Formation". Journal of Bone and Mineral Research. 25 (6): 091211115834058–35. doi:10.1359/jbmr.091110. PMID 19929436. S2CID 207269687.
Obamuyide, HA; Ogunlade, SO (March 2015). "A Tumour for which Surgery will do more harm than good: A Case Report of Fibrodysplasia Ossificans Progressiva". The Nigerian Postgraduate Medical Journal. 22 (1): 83–8. doi:10.4103/1117-1936.163373. PMID 25875418. S2CID 33239264. ProQuest 1850178336.
J. W. Lowery; V. Rosen (2012). "Allele-Specific RNA Interference in FOP Silencing the FOP gene". Gene Therapy. 19 (7): 701–702. doi:10.1038/gt.2011.190. PMID 22130446. S2CID 24990800.

springer.com (Global: 274^th place; English: 309^th place)

link.springer.com

Bauer, Adam H.; Bonham, Jeff; Gutierrez, Luis; Hsiao, Edward C.; Motamedi, Daria (August 2018). "Fibrodysplasia ossificans progressiva: a current review of imaging findings". Skeletal Radiology. 47 (8): 1043–1050. doi:10.1007/s00256-018-2889-5. ISSN 0364-2348.

theatlantic.com (Global: 228^th place; English: 158^th place)

Maeder, Thomas (1 February 1998). "A Few Hundred People Turned To Bone". The Atlantic. Retrieved 8 May 2022.

upenn.edu (Global: 702^nd place; English: 520^th place)

almanac.upenn.edu

"Frederick Kaplan: Rare Impact Award" (PDF). Almanac. 63 (32). University of Pennsylvania: 7. 25 April 2017. Retrieved 8 May 2022.

web.archive.org (Global: 1^st place; English: 1^st place)

Pinkowski, Jen (1 March 2019). "Here's what happens when your body tissues turn to bone". National Geographic. Archived from the original on 3 March 2019.
"Mütter Museum Reveals New Exhibit: Philadelphia Woman's Skeleton With Rare Bone Disease". Mütter Museum. 5 March 2019. Archived from the original on 28 August 2021. Retrieved 7 March 2020.
American Academy of Orthopaedic Surgeons (May 2006). "Fibrodysplasia Ossificans Progressiva (FOP)". orthoinfo.aaos.org. Archived from the original on 21 June 2012. Retrieved 7 October 2011.
Research, Center for Drug Evaluation and (17 August 2023). "FDA approves first treatment for Fibrodysplasia Ossificans Progressiva". FDA. Archived from the original on 18 August 2023.
"Health Canada Approves Ipsen's Sohonos (palovarotene capsules) as the First Approved Treatment for Fibrodysplasia Ossificans Progressiva" (Press release). Ipsen. 24 January 2022. Archived from the original on 29 May 2022. Retrieved 28 May 2022 – via Business Wire.
"Pipeline". www.clementiapharma.com. Archived from the original on 29 September 2015. Retrieved 22 November 2015.

worldcat.org (Global: 5^th place; English: 5^th place)

search.worldcat.org

Peltier, Leonard F. (January 1998). "A Case of Extraordinary Exostoses on the Back of a Boy". Clinical Orthopaedics and Related Research. 346: 5–6. doi:10.1097/00003086-199801000-00002. ISSN 0009-921X.
Lin, Shuxian; Svoboda, Kathy K. H.; Feng, Jian Q.; Jiang, Xinquan (5 April 2016). "The biological function of type I receptors of bone morphogenetic protein in bone". Bone Research. 4 (1): 16005. doi:10.1038/boneres.2016.5. ISSN 2095-6231. PMC 4820739. PMID 27088043.
Bauer, Adam H.; Bonham, Jeff; Gutierrez, Luis; Hsiao, Edward C.; Motamedi, Daria (August 2018). "Fibrodysplasia ossificans progressiva: a current review of imaging findings". Skeletal Radiology. 47 (8): 1043–1050. doi:10.1007/s00256-018-2889-5. ISSN 0364-2348.
Yamin, Ghiam; Daghighi, Shadi; Mafee, Mahmood (31 May 2021). "Fibrodysplasia ossificans progressiva (FOP) presenting as a rapidly growing non-calcified neck mass". Journal of Radiology Case Reports. 15 (5): 10–16. doi:10.3941/jrcr.v15i5.4103. ISSN 1943-0922. PMC 8253151. PMID 34276874.
Kaplan, Frederick S.; Le Merrer, Martine; Glaser, David L.; Pignolo, Robert J.; Goldsby, Robert; Kitterman, Joseph A.; Groppe, Jay; Shore, Eileen M. (March 2008). "Fibrodysplasia ossificans progressiva". Best Practice & Research. Clinical Rheumatology. 22 (1): 191–205. doi:10.1016/j.berh.2007.11.007. ISSN 1521-6942. PMC 2424023. PMID 18328989.
Pignolo, Robert J.; Hsiao, Edward C.; Al Mukaddam, Mona; Baujat, Geneviève; Berglund, Staffan K.; Brown, Matthew A.; Cheung, Angela M.; De Cunto, Carmen; Delai, Patricia; Haga, Nobuhiko; Kannu, Peter; Keen, Richard; Le Quan Sang, Kim‐Hanh; Mancilla, Edna E.; Marino, Rose (March 2023). "Reduction of New Heterotopic Ossification (HO) in the Open‐Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP)". Journal of Bone and Mineral Research. 38 (3): 381–394. doi:10.1002/jbmr.4762. ISSN 0884-0431.
Maruyama, Rika; Nguyen, Quynh; Roshmi, Rohini Roy; Touznik, Aleksander; Yokota, Toshifumi (June 2022). "Allele-Selective LNA Gapmers for the Treatment of Fibrodysplasia Ossificans Progressiva Knock Down the Pathogenic ACVR1R206H Transcript and Inhibit Osteogenic Differentiation". Nucleic Acid Therapeutics. 32 (3): 185–193. doi:10.1089/nat.2021.0009. ISSN 2159-3345. PMID 35085461.
Williams, Eleanor; Bagarova, Jana; Kerr, Georgina; Xia, Dong-Dong; Place, Elsie S.; Dey, Devaveena; Shen, Yue; Bocobo, Geoffrey A.; Mohedas, Agustin H.; Huang, Xiuli; Sanderson, Philip E. (2021). "Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva". JCI Insight. 6 (8) e95042. doi:10.1172/jci.insight.95042. ISSN 2379-3708. PMC 8119212. PMID 33705358.

Fibrodysplasia ossificans progressiva (English Wikipedia)

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