Fig4 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Fig4" in English language version.

Last modified: 23:35:13, 21 September 2026 (UTC)

Ref.Un. Ref.Website

Global rank English rank

5^th place

5^th place

2^nd place

2^nd place

630^th place

326^th place

42adsabs.harvard.edu

14^th place

9^th place

42semanticscholar.org

15^th place

8^th place

adsabs.harvard.edu (Global: 14^th place; English: 9^th place)

ui.adsabs.harvard.edu

Zhang Y, Zolov SN, Chow CY, Slutsky SG, Richardson SC, Piper RC, Yang B, Nau JJ, Westrick RJ, Morrison SJ, Meisler MH, Weisman LS (Oct 2007). "Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice". Proceedings of the National Academy of Sciences. 104 (44): 17518–23. Bibcode:2007PNAS..10417518Z. doi:10.1073/pnas.0702275104. PMC 2077288. PMID 17956977.
Chow CY, Zhang Y, Dowling JJ, Jin N, Adamska M, Shiga K, Szigeti K, Shy ME, Li J, Zhang X, Lupski JR, Weisman LS, Meisler MH (Jul 2007). "Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J". Nature. 448 (7149): 68–72. Bibcode:2007Natur.448...68C. doi:10.1038/nature05876. PMC 2271033. PMID 17572665.

doi.org (Global: 2^nd place; English: 2^nd place)

Erdman S, Lin L, Malczynski M, Snyder M (February 1998). "Pheromone-regulated genes required for yeast mating differentiation". Journal of Cell Biology. 140 (3): 461–83. doi:10.1083/jcb.140.3.461. PMC 2140177. PMID 9456310.
Hughes WE, Cooke FT, Parker PJ (Sep 2000). "Sac phosphatase domain proteins". Biochemical Journal. 350 (2): 337–52. doi:10.1042/0264-6021:3500337. PMC 1221260. PMID 10947947.
Novick P, Osmond BC, Botstein D (Apr 1989). "Suppressors of yeast actin mutations". Genetics. 121 (4): 659–74. doi:10.1093/genetics/121.4.659. PMC 1203651. PMID 2656401.
Minagawa T, Ijuin T, Mochizuki Y, Takenawa T (Jun 2001). "Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase". Journal of Biological Chemistry. 276 (25): 22011–5. doi:10.1074/jbc.M101579200. PMID 11274189.
Majerus PW, York JD (Apr 2009). "Phosphoinositide phosphatases and disease". Journal of Lipid Research. 50 (Suppl): S249–54. doi:10.1194/jlr.R800072-JLR200. PMC 2674710. PMID 19001665.
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A (Nov 2009). "Mammalian phosphoinositide kinases and phosphatases". Progress in Lipid Research. 48 (6): 307–43. doi:10.1016/j.plipres.2009.06.001. PMID 19580826.
Liu Y, Bankaitis VA (Jul 2010). "Phosphoinositide phosphatases in cell biology and disease". Progress in Lipid Research. 49 (3): 201–17. doi:10.1016/j.plipres.2009.12.001. PMC 2873057. PMID 20043944.
Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (Oct 1996). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Research. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
Sbrissa D, Ikonomov OC, Fu Z, Ijuin T, Gruenberg J, Takenawa T, Shisheva A (Aug 2007). "Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex". The Journal of Biological Chemistry. 282 (33): 23878–91. doi:10.1074/jbc.M611678200. PMID 17556371.
Yuan Y, Gao X, Guo N, Zhang H, Xie Z, Jin M, Li B, Yu L, Jing N (Nov 2007). "rSac3, a novel Sac domain phosphoinositide phosphatase, promotes neurite outgrowth in PC12 cells". Cell Research. 17 (11): 919–32. doi:10.1038/cr.2007.82. PMID 17909536.
Sbrissa D, Ikonomov OC, Fenner H, Shisheva A (Dec 2008). "ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality". Journal of Molecular Biology. 384 (4): 766–79. doi:10.1016/j.jmb.2008.10.009. PMC 2756758. PMID 18950639.
Ikonomov OC, Sbrissa D, Fenner H, Shisheva A (Dec 2009). "PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis". The Journal of Biological Chemistry. 284 (51): 35794–806. doi:10.1074/jbc.M109.037515. PMC 2791009. PMID 19840946.
Ikonomov OC, Sbrissa D, Delvecchio K, Xie Y, Jin JP, Rappolee D, Shisheva A (Apr 2011). "The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice". The Journal of Biological Chemistry. 286 (15): 13404–13. doi:10.1074/jbc.M111.222364. PMC 3075686. PMID 21349843.
Zhang Y, Zolov SN, Chow CY, Slutsky SG, Richardson SC, Piper RC, Yang B, Nau JJ, Westrick RJ, Morrison SJ, Meisler MH, Weisman LS (Oct 2007). "Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice". Proceedings of the National Academy of Sciences. 104 (44): 17518–23. Bibcode:2007PNAS..10417518Z. doi:10.1073/pnas.0702275104. PMC 2077288. PMID 17956977.
Chow CY, Zhang Y, Dowling JJ, Jin N, Adamska M, Shiga K, Szigeti K, Shy ME, Li J, Zhang X, Lupski JR, Weisman LS, Meisler MH (Jul 2007). "Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J". Nature. 448 (7149): 68–72. Bibcode:2007Natur.448...68C. doi:10.1038/nature05876. PMC 2271033. PMID 17572665.
Ikonomov OC, Sbrissa D, Fligger J, Delvecchio K, Shisheva A (Aug 2010). "ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder". The Journal of Biological Chemistry. 285 (35): 26760–4. doi:10.1074/jbc.C110.154658. PMC 2930674. PMID 20630877.
Ikonomov OC, Sbrissa D, Ijuin T, Takenawa T, Shisheva A (Sep 2009). "Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes". The Journal of Biological Chemistry. 284 (36): 23961–71. doi:10.1074/jbc.M109.025361. PMC 2781990. PMID 19578118.
Nicholson G, Lenk GM, Reddel SW, Grant AE, Towne CF, Ferguson CJ, Simpson E, Scheuerle A, Yasick M, Hoffman S, Blouin R, Brandt C, Coppola G, Biesecker LG, Batish SD, Meisler MH (Jul 2011). "Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P2 phosphatase FIG4". Brain. 134 (7): 1959–71. doi:10.1093/brain/awr148. PMC 3122378. PMID 21705420.
Lenk GM, Ferguson CJ, Chow CY, Jin N, Jones JM, Grant AE, Zolov SN, Winters JJ, Giger RJ, Dowling JJ, Weisman LS, Meisler MH (Jun 2011). "Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J". PLOS Genetics. 7 (6) e1002104. doi:10.1371/journal.pgen.1002104. PMC 3107197. PMID 21655088.
Hu B, McCollum M, Ravi V, Arpag S, Moiseev D, Castoro R, Mobley B, Burnette B, Suskind C, Day J, Yawn R, Feely S, Li Y, Yan Q, Shy M, Li J (Apr 2018). "Myelin abnormality in Charcot-Marie-Tooth type 4J recapitulates features of acquired demyelination". Annals of Neurology. 83 (4): 756–770. doi:10.1002/ana.25198. PMC 5912982. PMID 29518270.
Zhang X, Chow CY, Sahenk Z, Shy ME, Meisler MH, Li J (Aug 2008). "Mutation of FIG4 causes a rapidly progressive, asymmetric neuronal degeneration". Brain. 131 (8): 1990–2001. doi:10.1093/brain/awn114. PMC 2724900. PMID 18556664.
Shisheva A, Sbrissa D, Hu B, Li J (Dec 2019). "Severe Consequences of SAC3/FIG4 Phosphatase Deficiency to Phosphoinositides in Patients with Charcot-Marie-Tooth Disease Type-4J". Molecular Neurobiology. 56 (12): 8656–67. doi:10.1007/s12035-019-01693-8. PMC 11995980. PMID 31313076. S2CID 197423698.
Chow CY, Landers JE, Bergren SK, Sapp PC, Grant AE, Jones JM, Everett L, Lenk GM, McKenna-Yasek DM, Weisman LS, Figlewicz D, Brown RH, Meisler MH (Jan 2009). "Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS". The American Journal of Human Genetics. 84 (1): 85–8. doi:10.1016/j.ajhg.2008.12.010. PMC 2668033. PMID 19118816.
Ferguson CJ, Lenk GM, Meisler MH (Dec 2009). "Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2". Human Molecular Genetics. 18 (24): 4868–78. doi:10.1093/hmg/ddp460. PMC 2778378. PMID 19793721.
Katona I, Zhang X, Bai Y, Shy ME, Guo J, Yan Q, Hatfield J, Kupsky WJ, Li J (Apr 2011). "Distinct pathogenic processes between Fig4-deficient motor and sensory neurons". European Journal of Neuroscience. 33 (8): 1401–10. doi:10.1111/j.1460-9568.2011.07651.x. PMID 21410794. S2CID 24916509.
Erdman S, Lin L, Malczynski M, Snyder M (Feb 1998). "Pheromone-regulated genes required for yeast mating differentiation". Journal of Cell Biology. 140 (3): 461–83. doi:10.1083/jcb.140.3.461. PMC 2140177. PMID 9456310.
Rudge SA, Anderson DM, Emr SD (Jan 2004). "Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase". Molecular Biology of the Cell. 15 (1): 24–36. doi:10.1091/mbc.E03-05-0297. PMC 307524. PMID 14528018.
Botelho RJ, Efe JA, Teis D, Emr SD (Oct 2008). "Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase". Molecular Biology of the Cell. 19 (10): 4273–86. doi:10.1091/mbc.E08-04-0405. PMC 2555960. PMID 18653468.
Jin N, Chow CY, Liu L, Zolov SN, Bronson R, Davisson M, Petersen JL, Zhang Y, Park S, Duex JE, Goldowitz D, Meisler MH, Weisman LS (Dec 2008). "VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse". The EMBO Journal. 27 (24): 3221–34. doi:10.1038/emboj.2008.248. PMC 2600653. PMID 19037259.
Duex JE, Nau JJ, Kauffman EJ, Weisman LS (Apr 2006). "Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels". Eukaryotic Cell. 5 (4): 723–31. doi:10.1128/EC.5.4.723-731.2006. PMC 1459661. PMID 16607019.

ensembl.org (Global: 630^th place; English: 326^th place)

may2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000112367 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000038417 – Ensembl, May 2017

nih.gov (Global: 5^th place; English: 5^th place)

pubmed.ncbi.nlm.nih.gov

Erdman S, Lin L, Malczynski M, Snyder M (February 1998). "Pheromone-regulated genes required for yeast mating differentiation". Journal of Cell Biology. 140 (3): 461–83. doi:10.1083/jcb.140.3.461. PMC 2140177. PMID 9456310.
Hughes WE, Cooke FT, Parker PJ (Sep 2000). "Sac phosphatase domain proteins". Biochemical Journal. 350 (2): 337–52. doi:10.1042/0264-6021:3500337. PMC 1221260. PMID 10947947.
Novick P, Osmond BC, Botstein D (Apr 1989). "Suppressors of yeast actin mutations". Genetics. 121 (4): 659–74. doi:10.1093/genetics/121.4.659. PMC 1203651. PMID 2656401.
Minagawa T, Ijuin T, Mochizuki Y, Takenawa T (Jun 2001). "Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase". Journal of Biological Chemistry. 276 (25): 22011–5. doi:10.1074/jbc.M101579200. PMID 11274189.
Majerus PW, York JD (Apr 2009). "Phosphoinositide phosphatases and disease". Journal of Lipid Research. 50 (Suppl): S249–54. doi:10.1194/jlr.R800072-JLR200. PMC 2674710. PMID 19001665.
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A (Nov 2009). "Mammalian phosphoinositide kinases and phosphatases". Progress in Lipid Research. 48 (6): 307–43. doi:10.1016/j.plipres.2009.06.001. PMID 19580826.
Liu Y, Bankaitis VA (Jul 2010). "Phosphoinositide phosphatases in cell biology and disease". Progress in Lipid Research. 49 (3): 201–17. doi:10.1016/j.plipres.2009.12.001. PMC 2873057. PMID 20043944.
Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (Oct 1996). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Research. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
Sbrissa D, Ikonomov OC, Fu Z, Ijuin T, Gruenberg J, Takenawa T, Shisheva A (Aug 2007). "Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex". The Journal of Biological Chemistry. 282 (33): 23878–91. doi:10.1074/jbc.M611678200. PMID 17556371.
Yuan Y, Gao X, Guo N, Zhang H, Xie Z, Jin M, Li B, Yu L, Jing N (Nov 2007). "rSac3, a novel Sac domain phosphoinositide phosphatase, promotes neurite outgrowth in PC12 cells". Cell Research. 17 (11): 919–32. doi:10.1038/cr.2007.82. PMID 17909536.
Sbrissa D, Ikonomov OC, Fenner H, Shisheva A (Dec 2008). "ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality". Journal of Molecular Biology. 384 (4): 766–79. doi:10.1016/j.jmb.2008.10.009. PMC 2756758. PMID 18950639.
Ikonomov OC, Sbrissa D, Fenner H, Shisheva A (Dec 2009). "PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis". The Journal of Biological Chemistry. 284 (51): 35794–806. doi:10.1074/jbc.M109.037515. PMC 2791009. PMID 19840946.
Ikonomov OC, Sbrissa D, Delvecchio K, Xie Y, Jin JP, Rappolee D, Shisheva A (Apr 2011). "The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice". The Journal of Biological Chemistry. 286 (15): 13404–13. doi:10.1074/jbc.M111.222364. PMC 3075686. PMID 21349843.
Zhang Y, Zolov SN, Chow CY, Slutsky SG, Richardson SC, Piper RC, Yang B, Nau JJ, Westrick RJ, Morrison SJ, Meisler MH, Weisman LS (Oct 2007). "Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice". Proceedings of the National Academy of Sciences. 104 (44): 17518–23. Bibcode:2007PNAS..10417518Z. doi:10.1073/pnas.0702275104. PMC 2077288. PMID 17956977.
Chow CY, Zhang Y, Dowling JJ, Jin N, Adamska M, Shiga K, Szigeti K, Shy ME, Li J, Zhang X, Lupski JR, Weisman LS, Meisler MH (Jul 2007). "Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J". Nature. 448 (7149): 68–72. Bibcode:2007Natur.448...68C. doi:10.1038/nature05876. PMC 2271033. PMID 17572665.
Ikonomov OC, Sbrissa D, Fligger J, Delvecchio K, Shisheva A (Aug 2010). "ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder". The Journal of Biological Chemistry. 285 (35): 26760–4. doi:10.1074/jbc.C110.154658. PMC 2930674. PMID 20630877.
Ikonomov OC, Sbrissa D, Ijuin T, Takenawa T, Shisheva A (Sep 2009). "Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes". The Journal of Biological Chemistry. 284 (36): 23961–71. doi:10.1074/jbc.M109.025361. PMC 2781990. PMID 19578118.
Nicholson G, Lenk GM, Reddel SW, Grant AE, Towne CF, Ferguson CJ, Simpson E, Scheuerle A, Yasick M, Hoffman S, Blouin R, Brandt C, Coppola G, Biesecker LG, Batish SD, Meisler MH (Jul 2011). "Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P2 phosphatase FIG4". Brain. 134 (7): 1959–71. doi:10.1093/brain/awr148. PMC 3122378. PMID 21705420.
Lenk GM, Ferguson CJ, Chow CY, Jin N, Jones JM, Grant AE, Zolov SN, Winters JJ, Giger RJ, Dowling JJ, Weisman LS, Meisler MH (Jun 2011). "Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J". PLOS Genetics. 7 (6) e1002104. doi:10.1371/journal.pgen.1002104. PMC 3107197. PMID 21655088.
Hu B, McCollum M, Ravi V, Arpag S, Moiseev D, Castoro R, Mobley B, Burnette B, Suskind C, Day J, Yawn R, Feely S, Li Y, Yan Q, Shy M, Li J (Apr 2018). "Myelin abnormality in Charcot-Marie-Tooth type 4J recapitulates features of acquired demyelination". Annals of Neurology. 83 (4): 756–770. doi:10.1002/ana.25198. PMC 5912982. PMID 29518270.
Zhang X, Chow CY, Sahenk Z, Shy ME, Meisler MH, Li J (Aug 2008). "Mutation of FIG4 causes a rapidly progressive, asymmetric neuronal degeneration". Brain. 131 (8): 1990–2001. doi:10.1093/brain/awn114. PMC 2724900. PMID 18556664.
Shisheva A, Sbrissa D, Hu B, Li J (Dec 2019). "Severe Consequences of SAC3/FIG4 Phosphatase Deficiency to Phosphoinositides in Patients with Charcot-Marie-Tooth Disease Type-4J". Molecular Neurobiology. 56 (12): 8656–67. doi:10.1007/s12035-019-01693-8. PMC 11995980. PMID 31313076. S2CID 197423698.
Chow CY, Landers JE, Bergren SK, Sapp PC, Grant AE, Jones JM, Everett L, Lenk GM, McKenna-Yasek DM, Weisman LS, Figlewicz D, Brown RH, Meisler MH (Jan 2009). "Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS". The American Journal of Human Genetics. 84 (1): 85–8. doi:10.1016/j.ajhg.2008.12.010. PMC 2668033. PMID 19118816.
Ferguson CJ, Lenk GM, Meisler MH (Dec 2009). "Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2". Human Molecular Genetics. 18 (24): 4868–78. doi:10.1093/hmg/ddp460. PMC 2778378. PMID 19793721.
Katona I, Zhang X, Bai Y, Shy ME, Guo J, Yan Q, Hatfield J, Kupsky WJ, Li J (Apr 2011). "Distinct pathogenic processes between Fig4-deficient motor and sensory neurons". European Journal of Neuroscience. 33 (8): 1401–10. doi:10.1111/j.1460-9568.2011.07651.x. PMID 21410794. S2CID 24916509.
Erdman S, Lin L, Malczynski M, Snyder M (Feb 1998). "Pheromone-regulated genes required for yeast mating differentiation". Journal of Cell Biology. 140 (3): 461–83. doi:10.1083/jcb.140.3.461. PMC 2140177. PMID 9456310.
Rudge SA, Anderson DM, Emr SD (Jan 2004). "Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase". Molecular Biology of the Cell. 15 (1): 24–36. doi:10.1091/mbc.E03-05-0297. PMC 307524. PMID 14528018.
Botelho RJ, Efe JA, Teis D, Emr SD (Oct 2008). "Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase". Molecular Biology of the Cell. 19 (10): 4273–86. doi:10.1091/mbc.E08-04-0405. PMC 2555960. PMID 18653468.
Jin N, Chow CY, Liu L, Zolov SN, Bronson R, Davisson M, Petersen JL, Zhang Y, Park S, Duex JE, Goldowitz D, Meisler MH, Weisman LS (Dec 2008). "VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse". The EMBO Journal. 27 (24): 3221–34. doi:10.1038/emboj.2008.248. PMC 2600653. PMID 19037259.
Duex JE, Nau JJ, Kauffman EJ, Weisman LS (Apr 2006). "Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels". Eukaryotic Cell. 5 (4): 723–31. doi:10.1128/EC.5.4.723-731.2006. PMC 1459661. PMID 16607019.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: FIG4 FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)".
Erdman S, Lin L, Malczynski M, Snyder M (February 1998). "Pheromone-regulated genes required for yeast mating differentiation". Journal of Cell Biology. 140 (3): 461–83. doi:10.1083/jcb.140.3.461. PMC 2140177. PMID 9456310.
Hughes WE, Cooke FT, Parker PJ (Sep 2000). "Sac phosphatase domain proteins". Biochemical Journal. 350 (2): 337–52. doi:10.1042/0264-6021:3500337. PMC 1221260. PMID 10947947.
Novick P, Osmond BC, Botstein D (Apr 1989). "Suppressors of yeast actin mutations". Genetics. 121 (4): 659–74. doi:10.1093/genetics/121.4.659. PMC 1203651. PMID 2656401.
Majerus PW, York JD (Apr 2009). "Phosphoinositide phosphatases and disease". Journal of Lipid Research. 50 (Suppl): S249–54. doi:10.1194/jlr.R800072-JLR200. PMC 2674710. PMID 19001665.
Liu Y, Bankaitis VA (Jul 2010). "Phosphoinositide phosphatases in cell biology and disease". Progress in Lipid Research. 49 (3): 201–17. doi:10.1016/j.plipres.2009.12.001. PMC 2873057. PMID 20043944.
Sbrissa D, Ikonomov OC, Fenner H, Shisheva A (Dec 2008). "ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality". Journal of Molecular Biology. 384 (4): 766–79. doi:10.1016/j.jmb.2008.10.009. PMC 2756758. PMID 18950639.
Ikonomov OC, Sbrissa D, Fenner H, Shisheva A (Dec 2009). "PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis". The Journal of Biological Chemistry. 284 (51): 35794–806. doi:10.1074/jbc.M109.037515. PMC 2791009. PMID 19840946.
Ikonomov OC, Sbrissa D, Delvecchio K, Xie Y, Jin JP, Rappolee D, Shisheva A (Apr 2011). "The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice". The Journal of Biological Chemistry. 286 (15): 13404–13. doi:10.1074/jbc.M111.222364. PMC 3075686. PMID 21349843.
Zhang Y, Zolov SN, Chow CY, Slutsky SG, Richardson SC, Piper RC, Yang B, Nau JJ, Westrick RJ, Morrison SJ, Meisler MH, Weisman LS (Oct 2007). "Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice". Proceedings of the National Academy of Sciences. 104 (44): 17518–23. Bibcode:2007PNAS..10417518Z. doi:10.1073/pnas.0702275104. PMC 2077288. PMID 17956977.
Chow CY, Zhang Y, Dowling JJ, Jin N, Adamska M, Shiga K, Szigeti K, Shy ME, Li J, Zhang X, Lupski JR, Weisman LS, Meisler MH (Jul 2007). "Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J". Nature. 448 (7149): 68–72. Bibcode:2007Natur.448...68C. doi:10.1038/nature05876. PMC 2271033. PMID 17572665.
Ikonomov OC, Sbrissa D, Fligger J, Delvecchio K, Shisheva A (Aug 2010). "ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder". The Journal of Biological Chemistry. 285 (35): 26760–4. doi:10.1074/jbc.C110.154658. PMC 2930674. PMID 20630877.
Ikonomov OC, Sbrissa D, Ijuin T, Takenawa T, Shisheva A (Sep 2009). "Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes". The Journal of Biological Chemistry. 284 (36): 23961–71. doi:10.1074/jbc.M109.025361. PMC 2781990. PMID 19578118.
Nicholson G, Lenk GM, Reddel SW, Grant AE, Towne CF, Ferguson CJ, Simpson E, Scheuerle A, Yasick M, Hoffman S, Blouin R, Brandt C, Coppola G, Biesecker LG, Batish SD, Meisler MH (Jul 2011). "Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P2 phosphatase FIG4". Brain. 134 (7): 1959–71. doi:10.1093/brain/awr148. PMC 3122378. PMID 21705420.
Lenk GM, Ferguson CJ, Chow CY, Jin N, Jones JM, Grant AE, Zolov SN, Winters JJ, Giger RJ, Dowling JJ, Weisman LS, Meisler MH (Jun 2011). "Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J". PLOS Genetics. 7 (6) e1002104. doi:10.1371/journal.pgen.1002104. PMC 3107197. PMID 21655088.
Hu B, McCollum M, Ravi V, Arpag S, Moiseev D, Castoro R, Mobley B, Burnette B, Suskind C, Day J, Yawn R, Feely S, Li Y, Yan Q, Shy M, Li J (Apr 2018). "Myelin abnormality in Charcot-Marie-Tooth type 4J recapitulates features of acquired demyelination". Annals of Neurology. 83 (4): 756–770. doi:10.1002/ana.25198. PMC 5912982. PMID 29518270.
Zhang X, Chow CY, Sahenk Z, Shy ME, Meisler MH, Li J (Aug 2008). "Mutation of FIG4 causes a rapidly progressive, asymmetric neuronal degeneration". Brain. 131 (8): 1990–2001. doi:10.1093/brain/awn114. PMC 2724900. PMID 18556664.
Shisheva A, Sbrissa D, Hu B, Li J (Dec 2019). "Severe Consequences of SAC3/FIG4 Phosphatase Deficiency to Phosphoinositides in Patients with Charcot-Marie-Tooth Disease Type-4J". Molecular Neurobiology. 56 (12): 8656–67. doi:10.1007/s12035-019-01693-8. PMC 11995980. PMID 31313076. S2CID 197423698.
Chow CY, Landers JE, Bergren SK, Sapp PC, Grant AE, Jones JM, Everett L, Lenk GM, McKenna-Yasek DM, Weisman LS, Figlewicz D, Brown RH, Meisler MH (Jan 2009). "Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS". The American Journal of Human Genetics. 84 (1): 85–8. doi:10.1016/j.ajhg.2008.12.010. PMC 2668033. PMID 19118816.
Ferguson CJ, Lenk GM, Meisler MH (Dec 2009). "Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2". Human Molecular Genetics. 18 (24): 4868–78. doi:10.1093/hmg/ddp460. PMC 2778378. PMID 19793721.
Erdman S, Lin L, Malczynski M, Snyder M (Feb 1998). "Pheromone-regulated genes required for yeast mating differentiation". Journal of Cell Biology. 140 (3): 461–83. doi:10.1083/jcb.140.3.461. PMC 2140177. PMID 9456310.
Rudge SA, Anderson DM, Emr SD (Jan 2004). "Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase". Molecular Biology of the Cell. 15 (1): 24–36. doi:10.1091/mbc.E03-05-0297. PMC 307524. PMID 14528018.
Botelho RJ, Efe JA, Teis D, Emr SD (Oct 2008). "Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase". Molecular Biology of the Cell. 19 (10): 4273–86. doi:10.1091/mbc.E08-04-0405. PMC 2555960. PMID 18653468.
Jin N, Chow CY, Liu L, Zolov SN, Bronson R, Davisson M, Petersen JL, Zhang Y, Park S, Duex JE, Goldowitz D, Meisler MH, Weisman LS (Dec 2008). "VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse". The EMBO Journal. 27 (24): 3221–34. doi:10.1038/emboj.2008.248. PMC 2600653. PMID 19037259.
Duex JE, Nau JJ, Kauffman EJ, Weisman LS (Apr 2006). "Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels". Eukaryotic Cell. 5 (4): 723–31. doi:10.1128/EC.5.4.723-731.2006. PMC 1459661. PMID 16607019.

semanticscholar.org (Global: 15^th place; English: 8^th place)

api.semanticscholar.org

Shisheva A, Sbrissa D, Hu B, Li J (Dec 2019). "Severe Consequences of SAC3/FIG4 Phosphatase Deficiency to Phosphoinositides in Patients with Charcot-Marie-Tooth Disease Type-4J". Molecular Neurobiology. 56 (12): 8656–67. doi:10.1007/s12035-019-01693-8. PMC 11995980. PMID 31313076. S2CID 197423698.
Katona I, Zhang X, Bai Y, Shy ME, Guo J, Yan Q, Hatfield J, Kupsky WJ, Li J (Apr 2011). "Distinct pathogenic processes between Fig4-deficient motor and sensory neurons". European Journal of Neuroscience. 33 (8): 1401–10. doi:10.1111/j.1460-9568.2011.07651.x. PMID 21410794. S2CID 24916509.