First pass effect (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "First pass effect" in English language version.

refsWebsite

Global rank English rank

20nih.gov

4^th place

19doi.org

2^nd place

16worldcat.org

5^th place

7elsevier.com

610^th place

704^th place

3springer.com

274^th place

309^th place

2web.archive.org

1^st place

1semanticscholar.org

11^th place

8^th place

1sciencedirect.com

149^th place

178^th place

1nottingham.ac.uk

4,422^nd place

2,579^th place

1wiley.com

222^nd place

297^th place

1fda.gov

447^th place

338^th place

doi.org (Global: 2^nd place; English: 2^nd place)

Rowland, Malcolm (January 1972). "Influence of route of administration on drug availability". Journal of Pharmaceutical Sciences. 61 (1): 70–74. doi:10.1002/jps.2600610111. ISSN 0022-3549. PMID 5019220.
Pond, Susan M.; Tozer, Thomas N. (January 1984). "First-Pass Elimination". Clinical Pharmacokinetics. 9 (1): 1–25. doi:10.2165/00003088-198409010-00001. ISSN 0312-5963. PMID 6362950. S2CID 28006040.
Carlin, Michelle G. (2023-01-01), "Pharmacology and Mechanism of Action of Drugs", in Houck, Max M. (ed.), Encyclopedia of Forensic Sciences, Third Edition (Third Edition), Oxford: Elsevier, pp. 144–154, doi:10.1016/b978-0-12-823677-2.00086-6, ISBN 978-0-12-823678-9, retrieved 2024-01-17
Ilett, Kenneth F.; Tee, Lisa B. G.; Reeves, Philip T.; Minchin, Rodney F. (1990-01-01). "Mebolism of drugs and other xenobiotics in the gut lumen and wall". Pharmacology & Therapeutics. 46 (1): 67–93. doi:10.1016/0163-7258(90)90036-2. ISSN 0163-7258. PMID 2181492.
Thummel, Kenneth E.; Kunze, Kent L.; Shen, Danny D. (1997-09-15). "Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction". Advanced Drug Delivery Reviews. First-pass Metabolism and Its Impact on Oral Drug Delivery. 27 (2): 99–127. doi:10.1016/S0169-409X(97)00039-2. ISSN 0169-409X. PMID 10837554.
Drozdzik, Marek; Busch, Diana; Lapczuk, Joanna; Müller, Janett; Ostrowski, Marek; Kurzawski, Mateusz; Oswald, Stefan (2018). "Protein Abundance of Clinically Relevant Drug-Metabolizing Enzymes in the Human Liver and Intestine: A Comparative Analysis in Paired Tissue Specimens". Clinical Pharmacology & Therapeutics. 104 (3): 515–524. doi:10.1002/cpt.967. ISSN 1532-6535. PMID 29205295.
Doherty, Margaret M.; Charman, William N. (2002-04-01). "The Mucosa of the Small Intestine". Clinical Pharmacokinetics. 41 (4): 235–253. doi:10.2165/00003088-200241040-00001. ISSN 1179-1926. PMID 11978143.
Bramer, S. L.; Au, J. L.; Wientjes, M. G. (1993). "Gastrointestinal and hepatic first-pass elimination of 2',3'-dideoxyinosine in rats". The Journal of Pharmacology and Experimental Therapeutics. 265 (2): 731–738. doi:10.1016/S0022-3565(25)38201-7. ISSN 0022-3565. PMID 8496819.
Yan, Victoria C.; Muller, Florian L. (2020). "Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment". ACS Medicinal Chemistry Letters. 11 (7): 1361–1366. doi:10.1021/acsmedchemlett.0c00316. PMC 7315846. PMID 32665809.
Henriot, Justine; Dallmann, André; Dupuis, François; Perrier, Jérémy; Frechen, Sebastian (2025). "PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first-pass metabolism?". CPT: Pharmacometrics & Systems Pharmacology. 14 (1): 130–141. doi:10.1002/psp4.13249. ISSN 2163-8306. PMC 11706425. PMID 39359052.
Heikkinen, Aki T.; Baneyx, Guillaume; Caruso, Antonello; Parrott, Neil (2012-09-29). "Application of PBPK modeling to predict human intestinal metabolism of CYP3A substrates – An evaluation and case study using GastroPlus™". European Journal of Pharmaceutical Sciences. 47 (2): 375–386. doi:10.1016/j.ejps.2012.06.013. ISSN 0928-0987. PMID 22759901.
Gertz, Michael; Harrison, Anthony; Houston, J. Brian; Galetin, Aleksandra (2010). "Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data". Drug Metabolism and Disposition. 38 (7): 1147–1158. doi:10.1124/dmd.110.032649. ISSN 0090-9556. PMID 20368326.
Jones, Christopher R.; Hatley, Oliver J. D.; Ungell, Anna-Lena; Hilgendorf, Constanze; Peters, Sheila Annie; Rostami-Hodjegan, Amin (2016-05-01). "Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination". The AAPS Journal. 18 (3): 589–604. doi:10.1208/s12248-016-9889-y. ISSN 1550-7416. PMC 5256607. PMID 26964996.
Shakya, Ashok K.; Al-Najjar, Belal O.; Deb, Pran Kishore; Naik, Rajashri R.; Tekade, Rakesh K. (2018-01-01), Tekade, Rakesh K. (ed.), "Chapter 8 - First-Pass Metabolism Considerations in Pharmaceutical Product Development", Dosage Form Design Considerations, Advances in Pharmaceutical Product Development and Research, Academic Press, pp. 259–286, doi:10.1016/b978-0-12-814423-7.00008-3, ISBN 978-0-12-814423-7
Lee, Bo-Eun; Kim, Do-Kyung; Lee, Hyunil; Yoon, Siyeong; Park, Sin-Hyung; Lee, Soonchul; Yoo, Jongman (2021). "Recapitulation of First Pass Metabolism Using 3D Printed Microfluidic Chip and Organoid". Cells. 10 (12): 3301. doi:10.3390/cells10123301. ISSN 2073-4409. PMC 8699265. PMID 34943808.
Lee, Dong Wook; Ha, Sang Keun; Choi, Inwook; Sung, Jong Hwan (2017-11-07). "3D gut-liver chip with a PK model for prediction of first-pass metabolism". Biomedical Microdevices. 19 (4): 100. doi:10.1007/s10544-017-0242-8. ISSN 1572-8781. PMID 29116458.
Choe, Aerim; Ha, Sang Keun; Choi, Inwook; Choi, Nakwon; Sung, Jong Hwan (2017-01-10). "Microfluidic Gut-liver chip for reproducing the first pass metabolism". Biomedical Microdevices. 19 (1): 4. doi:10.1007/s10544-016-0143-2. ISSN 1572-8781. PMID 28074384.
de Boer, A. G.; Breimer, D. D. (1997-11-10). "Hepatic first-pass effect and controlled drug delivery following rectal administration". Advanced Drug Delivery Reviews. Rectal Drug Delivery. 28 (2): 229–237. doi:10.1016/S0169-409X(97)00074-4. ISSN 0169-409X.
Mathias, Neil R.; Hussain, Munir A. (2009). "Non-invasive Systemic Drug Delivery: Developability Considerations for Alternate Routes of Administration". Journal of Pharmaceutical Sciences. 99 (1): 1–20. doi:10.1002/jps.21793. ISSN 0022-3549. PMID 19499570.

elsevier.com (Global: 610^th place; English: 704^th place)

linkinghub.elsevier.com

Ilett, Kenneth F.; Tee, Lisa B. G.; Reeves, Philip T.; Minchin, Rodney F. (1990-01-01). "Mebolism of drugs and other xenobiotics in the gut lumen and wall". Pharmacology & Therapeutics. 46 (1): 67–93. doi:10.1016/0163-7258(90)90036-2. ISSN 0163-7258. PMID 2181492.
Thummel, Kenneth E.; Kunze, Kent L.; Shen, Danny D. (1997-09-15). "Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction". Advanced Drug Delivery Reviews. First-pass Metabolism and Its Impact on Oral Drug Delivery. 27 (2): 99–127. doi:10.1016/S0169-409X(97)00039-2. ISSN 0169-409X. PMID 10837554.
Heikkinen, Aki T.; Baneyx, Guillaume; Caruso, Antonello; Parrott, Neil (2012-09-29). "Application of PBPK modeling to predict human intestinal metabolism of CYP3A substrates – An evaluation and case study using GastroPlus™". European Journal of Pharmaceutical Sciences. 47 (2): 375–386. doi:10.1016/j.ejps.2012.06.013. ISSN 0928-0987. PMID 22759901.
Gertz, Michael; Harrison, Anthony; Houston, J. Brian; Galetin, Aleksandra (2010). "Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data". Drug Metabolism and Disposition. 38 (7): 1147–1158. doi:10.1124/dmd.110.032649. ISSN 0090-9556. PMID 20368326.
Shakya, Ashok K.; Al-Najjar, Belal O.; Deb, Pran Kishore; Naik, Rajashri R.; Tekade, Rakesh K. (2018-01-01), Tekade, Rakesh K. (ed.), "Chapter 8 - First-Pass Metabolism Considerations in Pharmaceutical Product Development", Dosage Form Design Considerations, Advances in Pharmaceutical Product Development and Research, Academic Press, pp. 259–286, doi:10.1016/b978-0-12-814423-7.00008-3, ISBN 978-0-12-814423-7
de Boer, A. G.; Breimer, D. D. (1997-11-10). "Hepatic first-pass effect and controlled drug delivery following rectal administration". Advanced Drug Delivery Reviews. Rectal Drug Delivery. 28 (2): 229–237. doi:10.1016/S0169-409X(97)00074-4. ISSN 0169-409X.
Mathias, Neil R.; Hussain, Munir A. (2009). "Non-invasive Systemic Drug Delivery: Developability Considerations for Alternate Routes of Administration". Journal of Pharmaceutical Sciences. 99 (1): 1–20. doi:10.1002/jps.21793. ISSN 0022-3549. PMID 19499570.

fda.gov (Global: 447^th place; English: 338^th place)

"Fact sheet for health care providers Emergency Use Authorization (EUA) of Veklury®(remdesivir)". Food and Drug Administration. Archived from the original on 12 May 2020. Retrieved 4 July 2024.

nih.gov (Global: 4^th place; English: 4^th place)

pubmed.ncbi.nlm.nih.gov

Rowland, Malcolm (January 1972). "Influence of route of administration on drug availability". Journal of Pharmaceutical Sciences. 61 (1): 70–74. doi:10.1002/jps.2600610111. ISSN 0022-3549. PMID 5019220.
Pond, Susan M.; Tozer, Thomas N. (January 1984). "First-Pass Elimination". Clinical Pharmacokinetics. 9 (1): 1–25. doi:10.2165/00003088-198409010-00001. ISSN 0312-5963. PMID 6362950. S2CID 28006040.
Ilett, Kenneth F.; Tee, Lisa B. G.; Reeves, Philip T.; Minchin, Rodney F. (1990-01-01). "Mebolism of drugs and other xenobiotics in the gut lumen and wall". Pharmacology & Therapeutics. 46 (1): 67–93. doi:10.1016/0163-7258(90)90036-2. ISSN 0163-7258. PMID 2181492.
Thummel, Kenneth E.; Kunze, Kent L.; Shen, Danny D. (1997-09-15). "Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction". Advanced Drug Delivery Reviews. First-pass Metabolism and Its Impact on Oral Drug Delivery. 27 (2): 99–127. doi:10.1016/S0169-409X(97)00039-2. ISSN 0169-409X. PMID 10837554.
Drozdzik, Marek; Busch, Diana; Lapczuk, Joanna; Müller, Janett; Ostrowski, Marek; Kurzawski, Mateusz; Oswald, Stefan (2018). "Protein Abundance of Clinically Relevant Drug-Metabolizing Enzymes in the Human Liver and Intestine: A Comparative Analysis in Paired Tissue Specimens". Clinical Pharmacology & Therapeutics. 104 (3): 515–524. doi:10.1002/cpt.967. ISSN 1532-6535. PMID 29205295.
Doherty, Margaret M.; Charman, William N. (2002-04-01). "The Mucosa of the Small Intestine". Clinical Pharmacokinetics. 41 (4): 235–253. doi:10.2165/00003088-200241040-00001. ISSN 1179-1926. PMID 11978143.
Bramer, S. L.; Au, J. L.; Wientjes, M. G. (1993). "Gastrointestinal and hepatic first-pass elimination of 2',3'-dideoxyinosine in rats". The Journal of Pharmacology and Experimental Therapeutics. 265 (2): 731–738. doi:10.1016/S0022-3565(25)38201-7. ISSN 0022-3565. PMID 8496819.
Yan, Victoria C.; Muller, Florian L. (2020). "Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment". ACS Medicinal Chemistry Letters. 11 (7): 1361–1366. doi:10.1021/acsmedchemlett.0c00316. PMC 7315846. PMID 32665809.
Henriot, Justine; Dallmann, André; Dupuis, François; Perrier, Jérémy; Frechen, Sebastian (2025). "PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first-pass metabolism?". CPT: Pharmacometrics & Systems Pharmacology. 14 (1): 130–141. doi:10.1002/psp4.13249. ISSN 2163-8306. PMC 11706425. PMID 39359052.
Heikkinen, Aki T.; Baneyx, Guillaume; Caruso, Antonello; Parrott, Neil (2012-09-29). "Application of PBPK modeling to predict human intestinal metabolism of CYP3A substrates – An evaluation and case study using GastroPlus™". European Journal of Pharmaceutical Sciences. 47 (2): 375–386. doi:10.1016/j.ejps.2012.06.013. ISSN 0928-0987. PMID 22759901.
Gertz, Michael; Harrison, Anthony; Houston, J. Brian; Galetin, Aleksandra (2010). "Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data". Drug Metabolism and Disposition. 38 (7): 1147–1158. doi:10.1124/dmd.110.032649. ISSN 0090-9556. PMID 20368326.
Jones, Christopher R.; Hatley, Oliver J. D.; Ungell, Anna-Lena; Hilgendorf, Constanze; Peters, Sheila Annie; Rostami-Hodjegan, Amin (2016-05-01). "Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination". The AAPS Journal. 18 (3): 589–604. doi:10.1208/s12248-016-9889-y. ISSN 1550-7416. PMC 5256607. PMID 26964996.
Lee, Bo-Eun; Kim, Do-Kyung; Lee, Hyunil; Yoon, Siyeong; Park, Sin-Hyung; Lee, Soonchul; Yoo, Jongman (2021). "Recapitulation of First Pass Metabolism Using 3D Printed Microfluidic Chip and Organoid". Cells. 10 (12): 3301. doi:10.3390/cells10123301. ISSN 2073-4409. PMC 8699265. PMID 34943808.
Lee, Dong Wook; Ha, Sang Keun; Choi, Inwook; Sung, Jong Hwan (2017-11-07). "3D gut-liver chip with a PK model for prediction of first-pass metabolism". Biomedical Microdevices. 19 (4): 100. doi:10.1007/s10544-017-0242-8. ISSN 1572-8781. PMID 29116458.
Choe, Aerim; Ha, Sang Keun; Choi, Inwook; Choi, Nakwon; Sung, Jong Hwan (2017-01-10). "Microfluidic Gut-liver chip for reproducing the first pass metabolism". Biomedical Microdevices. 19 (1): 4. doi:10.1007/s10544-016-0143-2. ISSN 1572-8781. PMID 28074384.
Mathias, Neil R.; Hussain, Munir A. (2009). "Non-invasive Systemic Drug Delivery: Developability Considerations for Alternate Routes of Administration". Journal of Pharmaceutical Sciences. 99 (1): 1–20. doi:10.1002/jps.21793. ISSN 0022-3549. PMID 19499570.

ncbi.nlm.nih.gov

Yan, Victoria C.; Muller, Florian L. (2020). "Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment". ACS Medicinal Chemistry Letters. 11 (7): 1361–1366. doi:10.1021/acsmedchemlett.0c00316. PMC 7315846. PMID 32665809.
Henriot, Justine; Dallmann, André; Dupuis, François; Perrier, Jérémy; Frechen, Sebastian (2025). "PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first-pass metabolism?". CPT: Pharmacometrics & Systems Pharmacology. 14 (1): 130–141. doi:10.1002/psp4.13249. ISSN 2163-8306. PMC 11706425. PMID 39359052.
Jones, Christopher R.; Hatley, Oliver J. D.; Ungell, Anna-Lena; Hilgendorf, Constanze; Peters, Sheila Annie; Rostami-Hodjegan, Amin (2016-05-01). "Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination". The AAPS Journal. 18 (3): 589–604. doi:10.1208/s12248-016-9889-y. ISSN 1550-7416. PMC 5256607. PMID 26964996.
Lee, Bo-Eun; Kim, Do-Kyung; Lee, Hyunil; Yoon, Siyeong; Park, Sin-Hyung; Lee, Soonchul; Yoo, Jongman (2021). "Recapitulation of First Pass Metabolism Using 3D Printed Microfluidic Chip and Organoid". Cells. 10 (12): 3301. doi:10.3390/cells10123301. ISSN 2073-4409. PMC 8699265. PMID 34943808.

nottingham.ac.uk (Global: 4,422^nd place; English: 2,579^th place)

Bath-Hextall, Fiona (October 16, 2013). "Understanding First Pass Metabolism". University of Nottingham. Archived from the original on July 28, 2021. Retrieved October 26, 2017.

sciencedirect.com (Global: 149^th place; English: 178^th place)

Carlin, Michelle G. (2023-01-01), "Pharmacology and Mechanism of Action of Drugs", in Houck, Max M. (ed.), Encyclopedia of Forensic Sciences, Third Edition (Third Edition), Oxford: Elsevier, pp. 144–154, doi:10.1016/b978-0-12-823677-2.00086-6, ISBN 978-0-12-823678-9, retrieved 2024-01-17

semanticscholar.org (Global: 11^th place; English: 8^th place)

api.semanticscholar.org

Pond, Susan M.; Tozer, Thomas N. (January 1984). "First-Pass Elimination". Clinical Pharmacokinetics. 9 (1): 1–25. doi:10.2165/00003088-198409010-00001. ISSN 0312-5963. PMID 6362950. S2CID 28006040.

springer.com (Global: 274^th place; English: 309^th place)

link.springer.com

Doherty, Margaret M.; Charman, William N. (2002-04-01). "The Mucosa of the Small Intestine". Clinical Pharmacokinetics. 41 (4): 235–253. doi:10.2165/00003088-200241040-00001. ISSN 1179-1926. PMID 11978143.
Lee, Dong Wook; Ha, Sang Keun; Choi, Inwook; Sung, Jong Hwan (2017-11-07). "3D gut-liver chip with a PK model for prediction of first-pass metabolism". Biomedical Microdevices. 19 (4): 100. doi:10.1007/s10544-017-0242-8. ISSN 1572-8781. PMID 29116458.
Choe, Aerim; Ha, Sang Keun; Choi, Inwook; Choi, Nakwon; Sung, Jong Hwan (2017-01-10). "Microfluidic Gut-liver chip for reproducing the first pass metabolism". Biomedical Microdevices. 19 (1): 4. doi:10.1007/s10544-016-0143-2. ISSN 1572-8781. PMID 28074384.

web.archive.org (Global: 1^st place; English: 1^st place)

Bath-Hextall, Fiona (October 16, 2013). "Understanding First Pass Metabolism". University of Nottingham. Archived from the original on July 28, 2021. Retrieved October 26, 2017.
"Fact sheet for health care providers Emergency Use Authorization (EUA) of Veklury®(remdesivir)". Food and Drug Administration. Archived from the original on 12 May 2020. Retrieved 4 July 2024.

wiley.com (Global: 222^nd place; English: 297^th place)

ascpt.onlinelibrary.wiley.com

Drozdzik, Marek; Busch, Diana; Lapczuk, Joanna; Müller, Janett; Ostrowski, Marek; Kurzawski, Mateusz; Oswald, Stefan (2018). "Protein Abundance of Clinically Relevant Drug-Metabolizing Enzymes in the Human Liver and Intestine: A Comparative Analysis in Paired Tissue Specimens". Clinical Pharmacology & Therapeutics. 104 (3): 515–524. doi:10.1002/cpt.967. ISSN 1532-6535. PMID 29205295.

worldcat.org (Global: 5^th place; English: 5^th place)

search.worldcat.org

Rowland, Malcolm (January 1972). "Influence of route of administration on drug availability". Journal of Pharmaceutical Sciences. 61 (1): 70–74. doi:10.1002/jps.2600610111. ISSN 0022-3549. PMID 5019220.
Pond, Susan M.; Tozer, Thomas N. (January 1984). "First-Pass Elimination". Clinical Pharmacokinetics. 9 (1): 1–25. doi:10.2165/00003088-198409010-00001. ISSN 0312-5963. PMID 6362950. S2CID 28006040.
Ilett, Kenneth F.; Tee, Lisa B. G.; Reeves, Philip T.; Minchin, Rodney F. (1990-01-01). "Mebolism of drugs and other xenobiotics in the gut lumen and wall". Pharmacology & Therapeutics. 46 (1): 67–93. doi:10.1016/0163-7258(90)90036-2. ISSN 0163-7258. PMID 2181492.
Thummel, Kenneth E.; Kunze, Kent L.; Shen, Danny D. (1997-09-15). "Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction". Advanced Drug Delivery Reviews. First-pass Metabolism and Its Impact on Oral Drug Delivery. 27 (2): 99–127. doi:10.1016/S0169-409X(97)00039-2. ISSN 0169-409X. PMID 10837554.
Drozdzik, Marek; Busch, Diana; Lapczuk, Joanna; Müller, Janett; Ostrowski, Marek; Kurzawski, Mateusz; Oswald, Stefan (2018). "Protein Abundance of Clinically Relevant Drug-Metabolizing Enzymes in the Human Liver and Intestine: A Comparative Analysis in Paired Tissue Specimens". Clinical Pharmacology & Therapeutics. 104 (3): 515–524. doi:10.1002/cpt.967. ISSN 1532-6535. PMID 29205295.
Doherty, Margaret M.; Charman, William N. (2002-04-01). "The Mucosa of the Small Intestine". Clinical Pharmacokinetics. 41 (4): 235–253. doi:10.2165/00003088-200241040-00001. ISSN 1179-1926. PMID 11978143.
Bramer, S. L.; Au, J. L.; Wientjes, M. G. (1993). "Gastrointestinal and hepatic first-pass elimination of 2',3'-dideoxyinosine in rats". The Journal of Pharmacology and Experimental Therapeutics. 265 (2): 731–738. doi:10.1016/S0022-3565(25)38201-7. ISSN 0022-3565. PMID 8496819.
Henriot, Justine; Dallmann, André; Dupuis, François; Perrier, Jérémy; Frechen, Sebastian (2025). "PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first-pass metabolism?". CPT: Pharmacometrics & Systems Pharmacology. 14 (1): 130–141. doi:10.1002/psp4.13249. ISSN 2163-8306. PMC 11706425. PMID 39359052.
Heikkinen, Aki T.; Baneyx, Guillaume; Caruso, Antonello; Parrott, Neil (2012-09-29). "Application of PBPK modeling to predict human intestinal metabolism of CYP3A substrates – An evaluation and case study using GastroPlus™". European Journal of Pharmaceutical Sciences. 47 (2): 375–386. doi:10.1016/j.ejps.2012.06.013. ISSN 0928-0987. PMID 22759901.
Gertz, Michael; Harrison, Anthony; Houston, J. Brian; Galetin, Aleksandra (2010). "Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data". Drug Metabolism and Disposition. 38 (7): 1147–1158. doi:10.1124/dmd.110.032649. ISSN 0090-9556. PMID 20368326.
Jones, Christopher R.; Hatley, Oliver J. D.; Ungell, Anna-Lena; Hilgendorf, Constanze; Peters, Sheila Annie; Rostami-Hodjegan, Amin (2016-05-01). "Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination". The AAPS Journal. 18 (3): 589–604. doi:10.1208/s12248-016-9889-y. ISSN 1550-7416. PMC 5256607. PMID 26964996.
Lee, Bo-Eun; Kim, Do-Kyung; Lee, Hyunil; Yoon, Siyeong; Park, Sin-Hyung; Lee, Soonchul; Yoo, Jongman (2021). "Recapitulation of First Pass Metabolism Using 3D Printed Microfluidic Chip and Organoid". Cells. 10 (12): 3301. doi:10.3390/cells10123301. ISSN 2073-4409. PMC 8699265. PMID 34943808.
Lee, Dong Wook; Ha, Sang Keun; Choi, Inwook; Sung, Jong Hwan (2017-11-07). "3D gut-liver chip with a PK model for prediction of first-pass metabolism". Biomedical Microdevices. 19 (4): 100. doi:10.1007/s10544-017-0242-8. ISSN 1572-8781. PMID 29116458.
Choe, Aerim; Ha, Sang Keun; Choi, Inwook; Choi, Nakwon; Sung, Jong Hwan (2017-01-10). "Microfluidic Gut-liver chip for reproducing the first pass metabolism". Biomedical Microdevices. 19 (1): 4. doi:10.1007/s10544-016-0143-2. ISSN 1572-8781. PMID 28074384.
de Boer, A. G.; Breimer, D. D. (1997-11-10). "Hepatic first-pass effect and controlled drug delivery following rectal administration". Advanced Drug Delivery Reviews. Rectal Drug Delivery. 28 (2): 229–237. doi:10.1016/S0169-409X(97)00074-4. ISSN 0169-409X.
Mathias, Neil R.; Hussain, Munir A. (2009). "Non-invasive Systemic Drug Delivery: Developability Considerations for Alternate Routes of Administration". Journal of Pharmaceutical Sciences. 99 (1): 1–20. doi:10.1002/jps.21793. ISSN 0022-3549. PMID 19499570.

First pass effect (English Wikipedia)

doi.org (Global: 2nd place; English: 2nd place)

elsevier.com (Global: 610th place; English: 704th place)

linkinghub.elsevier.com

fda.gov (Global: 447th place; English: 338th place)

nih.gov (Global: 4th place; English: 4th place)