Gene therapy for osteoarthritis (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Gene therapy for osteoarthritis" in English language version.

refsWebsite

Global rank English rank

81nih.gov

4^th place

54doi.org

2^nd place

14semanticscholar.org

11^th place

8^th place

3harvard.edu

18^th place

17^th place

2cdc.gov

218^th place

212^th place

2clinicaltrials.gov

5,225^th place

4,062^nd place

1fda.gov

447^th place

338^th place

1bmj.com

1,226^th place

1,421^st place

1worldcat.org

5^th place

bmj.com

ard.bmj.com

Conaghan PG, Katz N, Hunter D, Guermazi A, Hochberg M, Somberg K, et al. (2023-06-01). "Pos1348 Effects of Sprifermin on a Novel Outcome of Osteoarthritis Symptom Progression: Post-Hoc Analysis of the Forward Randomized Trial". Annals of the Rheumatic Diseases. 82 (Suppl 1): 1025–1026. doi:10.1136/annrheumdis-2023-eular.2454. ISSN 0003-4967.

cdc.gov

"Osteoarthritis (OA) | Arthritis | CDC". www.cdc.gov. 2020-08-04. Retrieved 2023-07-23.
"Osteoarthritis". US Centers for Disease Control and Prevention. 26 January 2024. Retrieved 16 October 2024.

clinicaltrials.gov

Clinical trial number NCT00110916 for "Treatment for Patients With Osteoarthritis (OA) of the Knee" at ClinicalTrials.gov
Clinical trial number NCT02790723 for "Safety of Intra-Articular Sc-rAAV2.5IL-1Ra in Subjects With Moderate Knee OA (AAVIL-1Ra)" at ClinicalTrials.gov

doi.org

Evans CH, Ghivizzani SC, Robbins PD (January 2018). "Gene Delivery to Joints by Intra-Articular Injection". Human Gene Therapy. 29 (1): 2–14. doi:10.1089/hum.2017.181. PMC 5773261. PMID 29160173.
Aspden RM, Saunders FR (January 2019). "Osteoarthritis as an organ disease: from the cradle to the grave". European Cells & Materials. 37: 74–87. doi:10.22203/eCM.v037a06. PMID 30698270. S2CID 59410793.
Shane Anderson A, Loeser RF (February 2010). "Why is osteoarthritis an age-related disease?". Best Practice & Research. Clinical Rheumatology. 24 (1): 15–26. doi:10.1016/j.berh.2009.08.006. PMC 2818253. PMID 20129196.
Kampen WU, Tillmann B (December 1998). "Age-related changes in the articular cartilage of human sacroiliac joint". Anatomy and Embryology. 198 (6): 505–513. doi:10.1007/s004290050200. PMID 9833689. S2CID 6355869.
Bobacz K, Erlacher L, Smolen J, Soleiman A, Graninger WB (December 2004). "Chondrocyte number and proteoglycan synthesis in the aging and osteoarthritic human articular cartilage". Annals of the Rheumatic Diseases. 63 (12): 1618–1622. doi:10.1136/ard.2002.002162. PMC 1754840. PMID 15547085.
Sanchez-Lopez E, Coras R, Torres A, Lane NE, Guma M (May 2022). "Synovial inflammation in osteoarthritis progression". Nat Rev Rheumatol. 18 (5): 258–275. doi:10.1038/s41584-022-00749-9. PMC 9050956. PMID 35165404.
Pujol JP, Loyau G (Sep 1987). "Interleukin-1 and osteoarthritis". Life Sci. 41 (10): 1187–1198. doi:10.1016/0024-3205(87)90196-2. PMID 3306235.
Chevalier X (1997). "Upregulation of enzymatic activity by interleukin-1 in osteoarthritis". Biomed Pharmacother. 51 (2): 58–62. doi:10.1016/s0753-3322(97)87727-x. PMID 9161468.
Attur M, Zhou H, Samuels J, Krasnokutsky S, Yau M, Scher JU, Doherty M, Wilson AG, Bencardino J, Hochberg M, Jordan JM, Mitchell B, Kraus VB, Abramson SB (2020). "Interleukin 1 receptor antagonist (IL1RN) gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease". Ann Rheum Dis. 79 (3): 400–407. doi:10.1136/annrheumdis-2019-216055. PMC 7034355. PMID 31852669.
Watson Levings RS, Smith AD, Broome TA, Rice BL, Gibbs EP, Myara DA, Hyddmark EV, Nasri E, Zarezadeh A, Levings PP, Lu Y, White ME, Dacanay EA, Foremny GB, Evans CH, Morton AJ, Winter M, Dark MJ, Nickerson DM, Colahan PT, Ghivizzani SC (2018). "Self-Complementary Adeno-Associated Virus-Mediated Interleukin-1 Receptor Antagonist Gene Delivery for the Treatment of Osteoarthritis: Test of Efficacy in an Equine Model". Human Gene Ther Clin Dev. 29 (2): 101–112. doi:10.1089/humc.2017.143. PMC 6007806. PMID 29869535.
Hollander JM, Goraltchouk A, Rawal M, Liu J, Luppino F, Zeng L, Seregin A (March 2023). "Adeno-Associated Virus-Delivered Fibroblast Growth Factor 18 Gene Therapy Promotes Cartilage Anabolism". Cartilage. 14 (4): 492–505. doi:10.1177/19476035231158774. PMC 10807742. PMID 36879540. S2CID 257376179.
Nixon AJ, Grol MW, Lang HM, Ruan MZ, Stone A, Begum L, et al. (November 2018). "Disease-Modifying Osteoarthritis Treatment With Interleukin-1 Receptor Antagonist Gene Therapy in Small and Large Animal Models". Arthritis & Rheumatology. 70 (11): 1757–1768. doi:10.1002/art.40668. PMID 30044894. S2CID 51718790.
Evans CH, Ghivizzani SC, Robbins PD (January 2023). "Osteoarthritis gene therapy in 2022". Current Opinion in Rheumatology. 35 (1): 37–43. doi:10.1097/BOR.0000000000000918. PMC 9757842. PMID 36508307.
Fujii Y, Liu L, Yagasaki L, Inotsume M, Chiba T, Asahara H (June 2022). "Cartilage Homeostasis and Osteoarthritis". International Journal of Molecular Sciences. 23 (11): 6316. doi:10.3390/ijms23116316. PMC 9181530. PMID 35682994.
Seol D, Choe HH, Zheng H, Brouillette MJ, Fredericks DC, Petersen EB, et al. (May 2022). "Intra-Articular Adeno-Associated Virus-Mediated Proteoglycan 4 Gene Therapy for Preventing Posttraumatic Osteoarthritis". Human Gene Therapy. 33 (9–10): 529–540. doi:10.1089/hum.2021.177. PMC 9142765. PMID 34610749.
Eckstein F, Hochberg MC, Guehring H, Moreau F, Ona V, Bihlet AR, et al. (August 2021). "Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study". Annals of the Rheumatic Diseases. 80 (8): 1062–1069. doi:10.1136/annrheumdis-2020-219181. PMC 8292562. PMID 33962962.
Frisbie DD, McIlwraith CW (August 2001). "Gene therapy: future therapies in osteoarthritis". The Veterinary Clinics of North America. Equine Practice. 17 (2): 233–43, vi. doi:10.1016/S0749-0739(17)30059-7. PMID 15658173.
Cao P, Li Y, Tang Y, Ding C, Hunter DJ (May 2020). "Pharmacotherapy for knee osteoarthritis: current and emerging therapies". Expert Opinion on Pharmacotherapy. 21 (7): 797–809. doi:10.1080/14656566.2020.1732924. PMID 32100600. S2CID 211524903.
Ohnuki M, Takahashi K (October 2015). "Present and future challenges of induced pluripotent stem cells". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370 (1680): 20140367. doi:10.1098/rstb.2014.0367. PMC 4633996. PMID 26416678.
Hu X, White K, Olroyd AG, DeJesus R, Dominguez AA, Dowdle WE, et al. (May 2023). "Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques". Nature Biotechnology. 42 (3): 413–423. doi:10.1038/s41587-023-01784-x. PMC 10940156. PMID 37156915. S2CID 258567014.
Madry H, Luyten FP, Facchini A (March 2012). "Biological aspects of early osteoarthritis". Knee Surgery, Sports Traumatology, Arthroscopy. 20 (3): 407–422. doi:10.1007/s00167-011-1705-8. PMID 22009557. S2CID 31367901.
Felson DT, Lawrence RC, Dieppe PA, Hirsch R, Helmick CG, Jordan JM, et al. (October 2000). "Osteoarthritis: new insights. Part 1: the disease and its risk factors". Annals of Internal Medicine. 133 (8): 635–646. doi:10.7326/0003-4819-133-8-200010170-00016. PMID 11033593.
Gandhi R, Wasserstein D, Razak F, Davey JR, Mahomed NN (December 2010). "BMI independently predicts younger age at hip and knee replacement". Obesity. 18 (12): 2362–2366. doi:10.1038/oby.2010.72. PMID 20379147. S2CID 25043959.
Saraf A, Mikos AG (July 2006). "Gene delivery strategies for cartilage tissue engineering". Advanced Drug Delivery Reviews. 58 (4): 592–603. doi:10.1016/j.addr.2006.03.005. PMC 2702530. PMID 16766079.
Ertl HC (2022). "Immunogenicity and toxicity of AAV gene therapy". Frontiers in Immunology. 13: 975803. doi:10.3389/fimmu.2022.975803. PMC 9411526. PMID 36032092.
Chen X, Lim DA, Lawlor MW, Dimmock D, Vite CH, Lester T, et al. (February 2023). "Biodistribution of Adeno-Associated Virus Gene Therapy Following Cerebrospinal Fluid-Directed Administration". Human Gene Therapy. 34 (3–4): 94–111. doi:10.1089/hum.2022.163. PMID 36606687. S2CID 255466309.
Aalbers CJ, Bevaart L, Loiler S, de Cortie K, Wright JF, Mingozzi F, et al. (2015). "Preclinical Potency and Biodistribution Studies of an AAV 5 Vector Expressing Human Interferon-β (ART-I02) for Local Treatment of Patients with Rheumatoid Arthritis". PLOS ONE. 10 (6): e0130612. Bibcode:2015PLoSO..1030612A. doi:10.1371/journal.pone.0130612. PMC 4479517. PMID 26107769.
Payne KA, Lee HH, Haleem AM, Martins C, Yuan Z, Qiao C, et al. (August 2011). "Single intra-articular injection of adeno-associated virus results in stable and controllable in vivo transgene expression in normal rat knees". Osteoarthritis and Cartilage. 19 (8): 1058–1065. doi:10.1016/j.joca.2011.04.009. PMC 3139006. PMID 21571082. S2CID 206303224.
Nakagami H (September 2021). "Development of COVID-19 vaccines utilizing gene therapy technology". International Immunology. 33 (10): 521–527. doi:10.1093/intimm/dxab013. PMC 8083619. PMID 33772572.
Madry H, Kaul G, Cucchiarini M, Stein U, Zurakowski D, Remberger K, et al. (August 2005). "Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I)". Gene Therapy. 12 (15): 1171–1179. doi:10.1038/sj.gt.3302515. PMID 15815701.
Goomer RS, Maris TM, Gelberman R, Boyer M, Silva M, Amiel D (October 2000). "Nonviral in vivo gene therapy for tissue engineering of articular cartilage and tendon repair". Clinical Orthopaedics and Related Research. 379 (379 Suppl): S189–S200. doi:10.1097/00003086-200010001-00025. PMID 11039769. S2CID 26414603.
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Conaghan PG, Katz N, Hunter D, Guermazi A, Hochberg M, Somberg K, et al. (2023-06-01). "Pos1348 Effects of Sprifermin on a Novel Outcome of Osteoarthritis Symptom Progression: Post-Hoc Analysis of the Forward Randomized Trial". Annals of the Rheumatic Diseases. 82 (Suppl 1): 1025–1026. doi:10.1136/annrheumdis-2023-eular.2454. ISSN 0003-4967.
Haupt JL, Frisbie DD, McIlwraith CW, Robbins PD, Ghivizzani S, Evans CH, Nixon AJ (January 2005). "Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model". Journal of Orthopaedic Research. 23 (1): 118–126. doi:10.1016/j.orthres.2004.06.020. PMID 15607883.
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Evans CH (February 2004). "Gene therapies for osteoarthritis". Current Rheumatology Reports. 6 (1): 31–40. doi:10.1007/s11926-004-0081-5. PMID 14713400. S2CID 43252961.
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Frisbie DD, Ghivizzani SC, Robbins PD, Evans CH, McIlwraith CW (January 2002). "Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene". Gene Therapy. 9 (1): 12–20. doi:10.1038/sj.gt.3301608. PMID 11850718.
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fda.gov

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harvard.edu

ui.adsabs.harvard.edu

Aalbers CJ, Bevaart L, Loiler S, de Cortie K, Wright JF, Mingozzi F, et al. (2015). "Preclinical Potency and Biodistribution Studies of an AAV 5 Vector Expressing Human Interferon-β (ART-I02) for Local Treatment of Patients with Rheumatoid Arthritis". PLOS ONE. 10 (6): e0130612. Bibcode:2015PLoSO..1030612A. doi:10.1371/journal.pone.0130612. PMC 4479517. PMID 26107769.
Chen Q, Luo H, Zhou C, Yu H, Yao S, Fu F, et al. (2020). "Comparative intra-articular gene transfer of seven adeno-associated virus serotypes reveals that AAV2 mediates the most efficient transduction to mouse arthritic chondrocytes". PLOS ONE. 15 (12): e0243359. Bibcode:2020PLoSO..1543359C. doi:10.1371/journal.pone.0243359. PMC 7737971. PMID 33320893.
Bandara G, Mueller GM, Galea-Lauri J, Tindal MH, Georgescu HI, Suchanek MK, et al. (November 1993). "Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer". Proceedings of the National Academy of Sciences of the United States of America. 90 (22): 10764–10768. Bibcode:1993PNAS...9010764B. doi:10.1073/pnas.90.22.10764. PMC 47858. PMID 8248169.

nih.gov

pubmed.ncbi.nlm.nih.gov

Evans CH, Ghivizzani SC, Robbins PD (January 2018). "Gene Delivery to Joints by Intra-Articular Injection". Human Gene Therapy. 29 (1): 2–14. doi:10.1089/hum.2017.181. PMC 5773261. PMID 29160173.
West CR, Bedard NA, Duchman KR, Westermann RW, Callaghan JJ (2019). "Rates and Risk Factors for Revision Hip Arthroscopy". The Iowa Orthopaedic Journal. 39 (1): 95–99. PMC 6604537. PMID 31413682.
King LK, March L, Anandacoomarasamy A (2013). "Obesity & osteoarthritis". The Indian Journal of Medical Research. 138 (2): 185–193. PMC 3788203. PMID 24056594.
Aspden RM, Saunders FR (January 2019). "Osteoarthritis as an organ disease: from the cradle to the grave". European Cells & Materials. 37: 74–87. doi:10.22203/eCM.v037a06. PMID 30698270. S2CID 59410793.
Shane Anderson A, Loeser RF (February 2010). "Why is osteoarthritis an age-related disease?". Best Practice & Research. Clinical Rheumatology. 24 (1): 15–26. doi:10.1016/j.berh.2009.08.006. PMC 2818253. PMID 20129196.
Kampen WU, Tillmann B (December 1998). "Age-related changes in the articular cartilage of human sacroiliac joint". Anatomy and Embryology. 198 (6): 505–513. doi:10.1007/s004290050200. PMID 9833689. S2CID 6355869.
Bobacz K, Erlacher L, Smolen J, Soleiman A, Graninger WB (December 2004). "Chondrocyte number and proteoglycan synthesis in the aging and osteoarthritic human articular cartilage". Annals of the Rheumatic Diseases. 63 (12): 1618–1622. doi:10.1136/ard.2002.002162. PMC 1754840. PMID 15547085.
Sanchez-Lopez E, Coras R, Torres A, Lane NE, Guma M (May 2022). "Synovial inflammation in osteoarthritis progression". Nat Rev Rheumatol. 18 (5): 258–275. doi:10.1038/s41584-022-00749-9. PMC 9050956. PMID 35165404.
Pujol JP, Loyau G (Sep 1987). "Interleukin-1 and osteoarthritis". Life Sci. 41 (10): 1187–1198. doi:10.1016/0024-3205(87)90196-2. PMID 3306235.
Chevalier X (1997). "Upregulation of enzymatic activity by interleukin-1 in osteoarthritis". Biomed Pharmacother. 51 (2): 58–62. doi:10.1016/s0753-3322(97)87727-x. PMID 9161468.
Attur M, Zhou H, Samuels J, Krasnokutsky S, Yau M, Scher JU, Doherty M, Wilson AG, Bencardino J, Hochberg M, Jordan JM, Mitchell B, Kraus VB, Abramson SB (2020). "Interleukin 1 receptor antagonist (IL1RN) gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease". Ann Rheum Dis. 79 (3): 400–407. doi:10.1136/annrheumdis-2019-216055. PMC 7034355. PMID 31852669.
Watson Levings RS, Smith AD, Broome TA, Rice BL, Gibbs EP, Myara DA, Hyddmark EV, Nasri E, Zarezadeh A, Levings PP, Lu Y, White ME, Dacanay EA, Foremny GB, Evans CH, Morton AJ, Winter M, Dark MJ, Nickerson DM, Colahan PT, Ghivizzani SC (2018). "Self-Complementary Adeno-Associated Virus-Mediated Interleukin-1 Receptor Antagonist Gene Delivery for the Treatment of Osteoarthritis: Test of Efficacy in an Equine Model". Human Gene Ther Clin Dev. 29 (2): 101–112. doi:10.1089/humc.2017.143. PMC 6007806. PMID 29869535.
Hollander JM, Goraltchouk A, Rawal M, Liu J, Luppino F, Zeng L, Seregin A (March 2023). "Adeno-Associated Virus-Delivered Fibroblast Growth Factor 18 Gene Therapy Promotes Cartilage Anabolism". Cartilage. 14 (4): 492–505. doi:10.1177/19476035231158774. PMC 10807742. PMID 36879540. S2CID 257376179.
Nixon AJ, Grol MW, Lang HM, Ruan MZ, Stone A, Begum L, et al. (November 2018). "Disease-Modifying Osteoarthritis Treatment With Interleukin-1 Receptor Antagonist Gene Therapy in Small and Large Animal Models". Arthritis & Rheumatology. 70 (11): 1757–1768. doi:10.1002/art.40668. PMID 30044894. S2CID 51718790.
Evans CH, Ghivizzani SC, Robbins PD (January 2023). "Osteoarthritis gene therapy in 2022". Current Opinion in Rheumatology. 35 (1): 37–43. doi:10.1097/BOR.0000000000000918. PMC 9757842. PMID 36508307.
Fujii Y, Liu L, Yagasaki L, Inotsume M, Chiba T, Asahara H (June 2022). "Cartilage Homeostasis and Osteoarthritis". International Journal of Molecular Sciences. 23 (11): 6316. doi:10.3390/ijms23116316. PMC 9181530. PMID 35682994.
Seol D, Choe HH, Zheng H, Brouillette MJ, Fredericks DC, Petersen EB, et al. (May 2022). "Intra-Articular Adeno-Associated Virus-Mediated Proteoglycan 4 Gene Therapy for Preventing Posttraumatic Osteoarthritis". Human Gene Therapy. 33 (9–10): 529–540. doi:10.1089/hum.2021.177. PMC 9142765. PMID 34610749.
Eckstein F, Hochberg MC, Guehring H, Moreau F, Ona V, Bihlet AR, et al. (August 2021). "Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study". Annals of the Rheumatic Diseases. 80 (8): 1062–1069. doi:10.1136/annrheumdis-2020-219181. PMC 8292562. PMID 33962962.
Frisbie DD, McIlwraith CW (August 2001). "Gene therapy: future therapies in osteoarthritis". The Veterinary Clinics of North America. Equine Practice. 17 (2): 233–43, vi. doi:10.1016/S0749-0739(17)30059-7. PMID 15658173.
Cao P, Li Y, Tang Y, Ding C, Hunter DJ (May 2020). "Pharmacotherapy for knee osteoarthritis: current and emerging therapies". Expert Opinion on Pharmacotherapy. 21 (7): 797–809. doi:10.1080/14656566.2020.1732924. PMID 32100600. S2CID 211524903.
Ohnuki M, Takahashi K (October 2015). "Present and future challenges of induced pluripotent stem cells". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370 (1680): 20140367. doi:10.1098/rstb.2014.0367. PMC 4633996. PMID 26416678.
Hu X, White K, Olroyd AG, DeJesus R, Dominguez AA, Dowdle WE, et al. (May 2023). "Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques". Nature Biotechnology. 42 (3): 413–423. doi:10.1038/s41587-023-01784-x. PMC 10940156. PMID 37156915. S2CID 258567014.
Madry H, Luyten FP, Facchini A (March 2012). "Biological aspects of early osteoarthritis". Knee Surgery, Sports Traumatology, Arthroscopy. 20 (3): 407–422. doi:10.1007/s00167-011-1705-8. PMID 22009557. S2CID 31367901.
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Conaghan PG, Katz N, Hunter D, Guermazi A, Hochberg M, Somberg K, et al. (2023-06-01). "Pos1348 Effects of Sprifermin on a Novel Outcome of Osteoarthritis Symptom Progression: Post-Hoc Analysis of the Forward Randomized Trial". Annals of the Rheumatic Diseases. 82 (Suppl 1): 1025–1026. doi:10.1136/annrheumdis-2023-eular.2454. ISSN 0003-4967.