Ghrelin O-acyltransferase (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Ghrelin O-acyltransferase" in English language version.

refsWebsite

Global rank English rank

17nih.gov

4^th place

9doi.org

2^nd place

3semanticscholar.org

11^th place

8^th place

2ensembl.org

1,626^th place

1,007^th place

1rhythmtx.com

low place

1clinicaltrials.gov

5,225^th place

4,062^nd place

1harvard.edu

18^th place

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clinicaltrials.gov

Clinical trial number NCT03641417 for "BARI-INSIGHT: A Double-blind, Placebo-controlled, Within-subject, Cross-over Mechanistic Study Investigating the Role of Ghrelin in Regulating Appetite and Energy Intake in Patients Following Bariatric Surgery" at ClinicalTrials.gov

doi.org

Kojima M, Hamamoto A, Sato T (October 2016). "Ghrelin O-acyltransferase (GOAT), a specific enzyme that modifies ghrelin with a medium-chain fatty acid". Journal of Biochemistry. 160 (4): 189–194. doi:10.1093/jb/mvw046. PMID 27489223.
Taylor MS, Ruch TR, Hsiao PY, Hwang Y, Zhang P, Dai L, et al. (November 2013). "Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase". The Journal of Biological Chemistry. 288 (45): 32211–32228. doi:10.1074/jbc.M113.510313. PMC 3820860. PMID 24045953.
Hougland JL (February 2019). "Ghrelin octanoylation by ghrelin O-acyltransferase: Unique protein biochemistry underlying metabolic signaling". Biochemical Society Transactions. 47 (1): 169–178. doi:10.1042/BST20180436. PMID 30626708. S2CID 58566712.
Taylor MS, Dempsey DR, Hwang Y, Chen Z, Chu N, Boeke JD, Cole PA (October 2015). "Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs". Bioorganic Chemistry. 62: 64–73. doi:10.1016/j.bioorg.2015.07.003. PMC 4567917. PMID 26246082.
Yang J, Zhao TJ, Goldstein JL, Brown MS (August 2008). "Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides". Proceedings of the National Academy of Sciences of the United States of America. 105 (31): 10750–10755. Bibcode:2008PNAS..10510750Y. doi:10.1073/pnas.0805353105. PMC 2504781. PMID 18669668.
Sieburg MA, Cleverdon ER, Hougland JL (2019). "Biochemical Assays for Ghrelin Acylation and Inhibition of Ghrelin O-Acyltransferase". In Linder E (ed.). Protein Lipidation. Methods in Molecular Biology. Vol. 2009. New York, NY: Springer. pp. 227–241. doi:10.1007/978-1-4939-9532-5_18. ISBN 978-1-4939-9532-5. PMID 31152408. S2CID 172136458.
Khatib MN, Gaidhane S, Gaidhane AM, Simkhada P, Zahiruddin QS (February 2015). "Ghrelin O Acyl Transferase (GOAT) as a Novel Metabolic Regulatory Enzyme". Journal of Clinical and Diagnostic Research. 9 (2): LE01 – LE05. doi:10.7860/JCDR/2015/9787.5514. PMC 4378754. PMID 25859472.
Cleverdon ER, Davis TR, Hougland JL (September 2018). "Functional group and stereochemical requirements for substrate binding by ghrelin O-acyltransferase revealed by unnatural amino acid incorporation". Bioorganic Chemistry. 79: 98–106. doi:10.1016/j.bioorg.2018.04.009. PMID 29738973. S2CID 13724720.
McGovern-Gooch KR, Mahajani NS, Garagozzo A, Schramm AJ, Hannah LG, Sieburg MA, et al. (February 2017). "Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation". Biochemistry. 56 (7): 919–931. doi:10.1021/acs.biochem.6b01008. PMC 5319884. PMID 28134508.

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000177669 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000071113 – Ensembl, May 2017

harvard.edu

ui.adsabs.harvard.edu

Yang J, Zhao TJ, Goldstein JL, Brown MS (August 2008). "Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides". Proceedings of the National Academy of Sciences of the United States of America. 105 (31): 10750–10755. Bibcode:2008PNAS..10510750Y. doi:10.1073/pnas.0805353105. PMC 2504781. PMID 18669668.

nih.gov

pubmed.ncbi.nlm.nih.gov

Kojima M, Hamamoto A, Sato T (October 2016). "Ghrelin O-acyltransferase (GOAT), a specific enzyme that modifies ghrelin with a medium-chain fatty acid". Journal of Biochemistry. 160 (4): 189–194. doi:10.1093/jb/mvw046. PMID 27489223.
Taylor MS, Ruch TR, Hsiao PY, Hwang Y, Zhang P, Dai L, et al. (November 2013). "Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase". The Journal of Biological Chemistry. 288 (45): 32211–32228. doi:10.1074/jbc.M113.510313. PMC 3820860. PMID 24045953.
Hougland JL (February 2019). "Ghrelin octanoylation by ghrelin O-acyltransferase: Unique protein biochemistry underlying metabolic signaling". Biochemical Society Transactions. 47 (1): 169–178. doi:10.1042/BST20180436. PMID 30626708. S2CID 58566712.
Taylor MS, Dempsey DR, Hwang Y, Chen Z, Chu N, Boeke JD, Cole PA (October 2015). "Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs". Bioorganic Chemistry. 62: 64–73. doi:10.1016/j.bioorg.2015.07.003. PMC 4567917. PMID 26246082.
Yang J, Zhao TJ, Goldstein JL, Brown MS (August 2008). "Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides". Proceedings of the National Academy of Sciences of the United States of America. 105 (31): 10750–10755. Bibcode:2008PNAS..10510750Y. doi:10.1073/pnas.0805353105. PMC 2504781. PMID 18669668.
Sieburg MA, Cleverdon ER, Hougland JL (2019). "Biochemical Assays for Ghrelin Acylation and Inhibition of Ghrelin O-Acyltransferase". In Linder E (ed.). Protein Lipidation. Methods in Molecular Biology. Vol. 2009. New York, NY: Springer. pp. 227–241. doi:10.1007/978-1-4939-9532-5_18. ISBN 978-1-4939-9532-5. PMID 31152408. S2CID 172136458.
Khatib MN, Gaidhane S, Gaidhane AM, Simkhada P, Zahiruddin QS (February 2015). "Ghrelin O Acyl Transferase (GOAT) as a Novel Metabolic Regulatory Enzyme". Journal of Clinical and Diagnostic Research. 9 (2): LE01 – LE05. doi:10.7860/JCDR/2015/9787.5514. PMC 4378754. PMID 25859472.
Cleverdon ER, Davis TR, Hougland JL (September 2018). "Functional group and stereochemical requirements for substrate binding by ghrelin O-acyltransferase revealed by unnatural amino acid incorporation". Bioorganic Chemistry. 79: 98–106. doi:10.1016/j.bioorg.2018.04.009. PMID 29738973. S2CID 13724720.
McGovern-Gooch KR, Mahajani NS, Garagozzo A, Schramm AJ, Hannah LG, Sieburg MA, et al. (February 2017). "Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation". Biochemistry. 56 (7): 919–931. doi:10.1021/acs.biochem.6b01008. PMC 5319884. PMID 28134508.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Membrane bound O-acyltransferase domain containing 4".
Taylor MS, Ruch TR, Hsiao PY, Hwang Y, Zhang P, Dai L, et al. (November 2013). "Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase". The Journal of Biological Chemistry. 288 (45): 32211–32228. doi:10.1074/jbc.M113.510313. PMC 3820860. PMID 24045953.
Taylor MS, Dempsey DR, Hwang Y, Chen Z, Chu N, Boeke JD, Cole PA (October 2015). "Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs". Bioorganic Chemistry. 62: 64–73. doi:10.1016/j.bioorg.2015.07.003. PMC 4567917. PMID 26246082.
Yang J, Zhao TJ, Goldstein JL, Brown MS (August 2008). "Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides". Proceedings of the National Academy of Sciences of the United States of America. 105 (31): 10750–10755. Bibcode:2008PNAS..10510750Y. doi:10.1073/pnas.0805353105. PMC 2504781. PMID 18669668.
Khatib MN, Gaidhane S, Gaidhane AM, Simkhada P, Zahiruddin QS (February 2015). "Ghrelin O Acyl Transferase (GOAT) as a Novel Metabolic Regulatory Enzyme". Journal of Clinical and Diagnostic Research. 9 (2): LE01 – LE05. doi:10.7860/JCDR/2015/9787.5514. PMC 4378754. PMID 25859472.
McGovern-Gooch KR, Mahajani NS, Garagozzo A, Schramm AJ, Hannah LG, Sieburg MA, et al. (February 2017). "Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation". Biochemistry. 56 (7): 919–931. doi:10.1021/acs.biochem.6b01008. PMC 5319884. PMID 28134508.

rhythmtx.com

ir.rhythmtx.com

"Rhythm Pharmaceuticals Announces Licensing Agreement with Takeda for the Development and Commercialization of Preclinical Treatment for Prader-Willi Syndrome | Rhythm Pharmaceuticals, Inc". ir.rhythmtx.com. Retrieved 2021-11-25.

semanticscholar.org

api.semanticscholar.org

Hougland JL (February 2019). "Ghrelin octanoylation by ghrelin O-acyltransferase: Unique protein biochemistry underlying metabolic signaling". Biochemical Society Transactions. 47 (1): 169–178. doi:10.1042/BST20180436. PMID 30626708. S2CID 58566712.
Sieburg MA, Cleverdon ER, Hougland JL (2019). "Biochemical Assays for Ghrelin Acylation and Inhibition of Ghrelin O-Acyltransferase". In Linder E (ed.). Protein Lipidation. Methods in Molecular Biology. Vol. 2009. New York, NY: Springer. pp. 227–241. doi:10.1007/978-1-4939-9532-5_18. ISBN 978-1-4939-9532-5. PMID 31152408. S2CID 172136458.
Cleverdon ER, Davis TR, Hougland JL (September 2018). "Functional group and stereochemical requirements for substrate binding by ghrelin O-acyltransferase revealed by unnatural amino acid incorporation". Bioorganic Chemistry. 79: 98–106. doi:10.1016/j.bioorg.2018.04.009. PMID 29738973. S2CID 13724720.