HERC2 (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "HERC2" in English language version.

refsWebsite

Global rank English rank

54nih.gov

4^th place

33doi.org

2^nd place

8semanticscholar.org

11^th place

8^th place

4harvard.edu

18^th place

17^th place

2ensembl.org

1,626^th place

1,007^th place

1bashaar.org.il

low place

1nbcnews.com

137^th place

101^st place

1livescience.com

1,190^th place

959^th place

1web.archive.org

1^st place

1ku.dk

5,396^th place

4,339^th place

1yale.edu

565^th place

460^th place

1uni-konstanz.de

low place

8,610^th place

1handle.net

102^nd place

76^th place

bashaar.org.il

Sturm RA, Larsson M (October 2009). "Genetics of human iris colour and patterns" (PDF). Pigment Cell & Melanoma Research. 22 (5): 544–62. doi:10.1111/j.1755-148X.2009.00606.x. PMID 19619260. S2CID 893259.

doi.org

Sánchez-Tena S, Cubillos-Rojas M, Schneider T, Rosa JL (May 2016). "Functional and pathological relevance of HERC family proteins: a decade later". Cellular and Molecular Life Sciences. 73 (10): 1955–68. doi:10.1007/s00018-016-2139-8. PMC 11108380. PMID 26801221. S2CID 7457614.
Hochrainer K, Mayer H, Baranyi U, Binder B, Lipp J, Kroismayr R (February 2005). "The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects". Genomics. 85 (2): 153–64. doi:10.1016/j.ygeno.2004.10.006. PMID 15676274.
Lehman AL, Nakatsu Y, Ching A, Bronson RT, Oakey RJ, Keiper-Hrynko N, Finger JN, Durham-Pierre D, Horton DB, Newton JM, Lyon MF, Brilliant MH (August 1998). "A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice". Proceedings of the National Academy of Sciences of the United States of America. 95 (16): 9436–41. Bibcode:1998PNAS...95.9436L. doi:10.1073/pnas.95.16.9436. PMC 21356. PMID 9689098.
Ji Y, Walkowicz MJ, Buiting K, Johnson DK, Tarvin RE, Rinchik EM, Horsthemke B, Stubbs L, Nicholls RD (March 1999). "The ancestral gene for transcribed, low-copy repeats in the Prader-Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities". Human Molecular Genetics. 8 (3): 533–42. doi:10.1093/hmg/8.3.533. PMID 9949213.
Brilliant MH (1992). "The mouse pink-eyed dilution locus: a model for aspects of Prader-Willi syndrome, Angelman syndrome, and a form of hypomelanosis of Ito". Mammalian Genome. 3 (4): 187–91. doi:10.1007/bf00355717. PMID 1611213. S2CID 32406842.
Ji Y, Rebert NA, Joslin JM, Higgins MJ, Schultz RA, Nicholls RD (March 2000). "Structure of the highly conserved HERC2 gene and of multiple partially duplicated paralogs in human". Genome Research. 10 (3): 319–29. doi:10.1101/gr.10.3.319. PMC 311424. PMID 10720573.
Kayser M, Liu F, Janssens AC, Rivadeneira F, Lao O, van Duijn K, Vermeulen M, Arp P, Jhamai MM, van Ijcken WF, den Dunnen JT, Heath S, Zelenika D, Despriet DD, Klaver CC, Vingerling JR, de Jong PT, Hofman A, Aulchenko YS, Uitterlinden AG, Oostra BA, van Duijn CM (February 2008). "Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene". American Journal of Human Genetics. 82 (2): 411–23. doi:10.1016/j.ajhg.2007.10.003. PMC 2427174. PMID 18252221.
Lemak A, Gutmanas A, Chitayat S, Karra M, Farès C, Sunnerhagen M, Arrowsmith CH (January 2011). "A novel strategy for NMR resonance assignment and protein structure determination". Journal of Biomolecular NMR. 49 (1): 27–38. doi:10.1007/s10858-010-9458-0. PMC 3715383. PMID 21161328.
Danielsen JR, Povlsen LK, Villumsen BH, Streicher W, Nilsson J, Wikström M, Bekker-Jensen S, Mailand N (April 2012). "DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger". The Journal of Cell Biology. 197 (2): 179–87. doi:10.1083/jcb.201106152. PMC 3328386. PMID 22508508.
Branicki W, Brudnik U, Wojas-Pelc A (March 2009). "Interactions between HERC2, OCA2 and MC1R may influence human pigmentation phenotype". Annals of Human Genetics. 73 (2): 160–70. doi:10.1111/j.1469-1809.2009.00504.x. PMID 19208107. S2CID 5233533.
Eiberg H, Troelsen J, Nielsen M, Mikkelsen A, Mengel-From J, Kjaer KW, Hansen L (March 2008). "Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression". Human Genetics. 123 (2): 177–87. doi:10.1007/s00439-007-0460-x. PMID 18172690. S2CID 9886658.
Sturm RA, Larsson M (October 2009). "Genetics of human iris colour and patterns" (PDF). Pigment Cell & Melanoma Research. 22 (5): 544–62. doi:10.1111/j.1755-148X.2009.00606.x. PMID 19619260. S2CID 893259.
Sturm RA, Duffy DL, Zhao ZZ, Leite FP, Stark MS, Hayward NK, Martin NG, Montgomery GW (February 2008). "A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color". American Journal of Human Genetics. 82 (2): 424–31. doi:10.1016/j.ajhg.2007.11.005. PMC 2427173. PMID 18252222.
Donnelly MP, Paschou P, Grigorenko E, Gurwitz D, Barta C, Lu RB, Zhukova OV, Kim JJ, Siniscalco M, New M, Li H, Kajuna SL, Manolopoulos VG, Speed WC, Pakstis AJ, Kidd JR, Kidd KK (May 2012). "A global view of the OCA2-HERC2 region and pigmentation". Human Genetics. 131 (5): 683–96. doi:10.1007/s00439-011-1110-x. PMC 3325407. PMID 22065085.
Branum ME, Reardon JT, Sancar A (July 2001). "DNA repair excision nuclease attacks undamaged DNA. A potential source of spontaneous mutations". The Journal of Biological Chemistry. 276 (27): 25421–6. doi:10.1074/jbc.M101032200. PMID 11353769.
Zhu M, Zhao H, Liao J, Xu X (December 2014). "HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability". Nucleic Acids Research. 42 (21): 13074–81. doi:10.1093/nar/gku978. PMC 4245974. PMID 25326330.
Yuan J, Luo K, Deng M, Li Y, Yin P, Gao B, Fang Y, Wu P, Liu T, Lou Z (December 2014). "HERC2-USP20 axis regulates DNA damage checkpoint through Claspin". Nucleic Acids Research. 42 (21): 13110–21. doi:10.1093/nar/gku1034. PMC 4245938. PMID 25355518.
Izawa N, Wu W, Sato K, Nishikawa H, Kato A, Boku N, Itoh F, Ohta T (September 2011). "HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progression". Cancer Research. 71 (17): 5621–5. doi:10.1158/0008-5472.CAN-11-0385. PMID 21775519.
Bekker-Jensen S, Rendtlew Danielsen J, Fugger K, Gromova I, Nerstedt A, Lukas C, Bartek J, Lukas J, Mailand N (January 2010). "HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes". Nature Cell Biology. 12 (1): 80–6, sup pp 1–12. doi:10.1038/ncb2008. PMID 20023648. S2CID 9996031.
Lee TH, Park JM, Leem SH, Kang TH (January 2014). "Coordinated regulation of XPA stability by ATR and HERC2 during nucleotide excision repair". Oncogene. 33 (1): 19–25. doi:10.1038/onc.2012.539. PMID 23178497.
Kang TH, Lindsey-Boltz LA, Reardon JT, Sancar A (March 2010). "Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase". Proceedings of the National Academy of Sciences of the United States of America. 107 (11): 4890–5. Bibcode:2010PNAS..107.4890K. doi:10.1073/pnas.0915085107. PMC 2841896. PMID 20304803.
Al-Hakim AK, Bashkurov M, Gingras AC, Durocher D, Pelletier L (June 2012). "Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture". Molecular & Cellular Proteomics. 11 (6): M111.014233. doi:10.1074/mcp.M111.014233. PMC 3433907. PMID 22261722.
Moroishi T, Yamauchi T, Nishiyama M, Nakayama KI (June 2014). "HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism". The Journal of Biological Chemistry. 289 (23): 16430–41. doi:10.1074/jbc.M113.541490. PMC 4047410. PMID 24778179.
Cubillos-Rojas M, Amair-Pinedo F, Peiró-Jordán R, Bartrons R, Ventura F, Rosa JL (May 2014). "The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization". The Journal of Biological Chemistry. 289 (21): 14782–95. doi:10.1074/jbc.M113.527978. PMC 4031533. PMID 24722987.
Kühnle S, Kogel U, Glockzin S, Marquardt A, Ciechanover A, Matentzoglu K, Scheffner M (June 2011). "Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2". The Journal of Biological Chemistry. 286 (22): 19410–6. doi:10.1074/jbc.M110.205211. PMC 3103319. PMID 21493713.
Harlalka GV, Baple EL, Cross H, Kühnle S, Cubillos-Rojas M, Matentzoglu K, Patton MA, Wagner K, Coblentz R, Ford DL, Mackay DJ, Chioza BA, Scheffner M, Rosa JL, Crosby AH (February 2013). "Mutation of HERC2 causes developmental delay with Angelman-like features" (PDF). Journal of Medical Genetics. 50 (2): 65–73. doi:10.1136/jmedgenet-2012-101367. PMID 23243086. S2CID 206997462.
Puffenberger EG, Jinks RN, Wang H, Xin B, Fiorentini C, Sherman EA, Degrazio D, Shaw C, Sougnez C, Cibulskis K, Gabriel S, Kelley RI, Morton DH, Strauss KA (December 2012). "A homozygous missense mutation in HERC2 associated with global developmental delay and autism spectrum disorder". Human Mutation. 33 (12): 1639–46. doi:10.1002/humu.22237. PMID 23065719. S2CID 10372349.
Morice-Picard F, Benard G, Rezvani HR, Lasseaux E, Simon D, Moutton S, Rooryck C, Lacombe D, Baumann C, Arveiler B (January 2016). "Complete loss of function of the ubiquitin ligase HERC2 causes a severe neurodevelopmental phenotype". European Journal of Human Genetics. 25 (1): 52–58. doi:10.1038/ejhg.2016.139. PMC 5159772. PMID 27759030.
Ferguson R, Vogelsang M, Ucisik-Akkaya E, Rai K, Pilarski R, Martinez CN, Rendleman J, Kazlow E, Nagdimov K, Osman I, Klein RJ, Davidorf FH, Cebulla CM, Abdel-Rahman MH, Kirchhoff T (August 2016). "Genetic markers of pigmentation are novel risk loci for uveal melanoma". Scientific Reports. 6 (1): 31191. Bibcode:2016NatSR...631191F. doi:10.1038/srep31191. PMC 4976361. PMID 27499155.
Yoo NJ, Park SW, Lee SH (December 2011). "Frameshift mutations of ubiquitination-related genes HERC2, HERC3, TRIP12, UBE2Q1 and UBE4B in gastric and colorectal carcinomas with microsatellite instability". Pathology. 43 (7): 753–5. doi:10.1097/pat.0b013e32834c7e78. PMID 22124266.
Wu W, Sato K, Koike A, Nishikawa H, Koizumi H, Venkitaraman AR, Ohta T (August 2010). "HERC2 is an E3 ligase that targets BRCA1 for degradation". Cancer Research. 70 (15): 6384–92. doi:10.1158/0008-5472.CAN-10-1304. PMID 20631078.
Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, Asano T, Yoshimi K, Zhang CL, Matsumoto G, Ohtsuka T, Kageyama R, Kiyonari H, Shioi G, Nukina N, Hattori N, Takahashi R (September 2015). "The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway". PLOS Genetics. 11 (9): e1005503. doi:10.1371/journal.pgen.1005503. PMC 4565672. PMID 26355680.
Fu Q, Posth C (May 2, 2016). "The genetic history of Ice Age Europe". Nature. 534 (7606): 200–205. Bibcode:2016Natur.534..200F. doi:10.1038/nature17993. hdl:10211.3/198594. PMC 4943878. PMID 27135931.

ensembl.org

May2017.archive.ensembl.org

ENSG00000276802, ENSG00000277278 GRCh38: Ensembl release 89: ENSG00000128731, ENSG00000276802, ENSG00000277278 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000030451 – Ensembl, May 2017

handle.net

hdl.handle.net

Fu Q, Posth C (May 2, 2016). "The genetic history of Ice Age Europe". Nature. 534 (7606): 200–205. Bibcode:2016Natur.534..200F. doi:10.1038/nature17993. hdl:10211.3/198594. PMC 4943878. PMID 27135931.

harvard.edu

ui.adsabs.harvard.edu

Lehman AL, Nakatsu Y, Ching A, Bronson RT, Oakey RJ, Keiper-Hrynko N, Finger JN, Durham-Pierre D, Horton DB, Newton JM, Lyon MF, Brilliant MH (August 1998). "A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice". Proceedings of the National Academy of Sciences of the United States of America. 95 (16): 9436–41. Bibcode:1998PNAS...95.9436L. doi:10.1073/pnas.95.16.9436. PMC 21356. PMID 9689098.
Kang TH, Lindsey-Boltz LA, Reardon JT, Sancar A (March 2010). "Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase". Proceedings of the National Academy of Sciences of the United States of America. 107 (11): 4890–5. Bibcode:2010PNAS..107.4890K. doi:10.1073/pnas.0915085107. PMC 2841896. PMID 20304803.
Ferguson R, Vogelsang M, Ucisik-Akkaya E, Rai K, Pilarski R, Martinez CN, Rendleman J, Kazlow E, Nagdimov K, Osman I, Klein RJ, Davidorf FH, Cebulla CM, Abdel-Rahman MH, Kirchhoff T (August 2016). "Genetic markers of pigmentation are novel risk loci for uveal melanoma". Scientific Reports. 6 (1): 31191. Bibcode:2016NatSR...631191F. doi:10.1038/srep31191. PMC 4976361. PMID 27499155.
Fu Q, Posth C (May 2, 2016). "The genetic history of Ice Age Europe". Nature. 534 (7606): 200–205. Bibcode:2016Natur.534..200F. doi:10.1038/nature17993. hdl:10211.3/198594. PMC 4943878. PMID 27135931.

ku.dk

Bryner J (2008-01-31). "Here's what made those brown eyes blue". Health News. NBC News. Retrieved 2008-11-06.; Bryner J (2008-01-31). "One Common Ancestor Behind Blue Eyes". LiveScience. Imaginova Corp. Retrieved 2008-11-06.; "Blue-eyed humans have a single, common ancestor". News. University of Copenhagen. 2008-01-30. Archived from the original on 2008-11-08. Retrieved 2008-11-06.

livescience.com

Bryner J (2008-01-31). "Here's what made those brown eyes blue". Health News. NBC News. Retrieved 2008-11-06.; Bryner J (2008-01-31). "One Common Ancestor Behind Blue Eyes". LiveScience. Imaginova Corp. Retrieved 2008-11-06.; "Blue-eyed humans have a single, common ancestor". News. University of Copenhagen. 2008-01-30. Archived from the original on 2008-11-08. Retrieved 2008-11-06.

nbcnews.com

Bryner J (2008-01-31). "Here's what made those brown eyes blue". Health News. NBC News. Retrieved 2008-11-06.; Bryner J (2008-01-31). "One Common Ancestor Behind Blue Eyes". LiveScience. Imaginova Corp. Retrieved 2008-11-06.; "Blue-eyed humans have a single, common ancestor". News. University of Copenhagen. 2008-01-30. Archived from the original on 2008-11-08. Retrieved 2008-11-06.

nih.gov

pubmed.ncbi.nlm.nih.gov

Sánchez-Tena S, Cubillos-Rojas M, Schneider T, Rosa JL (May 2016). "Functional and pathological relevance of HERC family proteins: a decade later". Cellular and Molecular Life Sciences. 73 (10): 1955–68. doi:10.1007/s00018-016-2139-8. PMC 11108380. PMID 26801221. S2CID 7457614.
Hochrainer K, Mayer H, Baranyi U, Binder B, Lipp J, Kroismayr R (February 2005). "The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects". Genomics. 85 (2): 153–64. doi:10.1016/j.ygeno.2004.10.006. PMID 15676274.
Lehman AL, Nakatsu Y, Ching A, Bronson RT, Oakey RJ, Keiper-Hrynko N, Finger JN, Durham-Pierre D, Horton DB, Newton JM, Lyon MF, Brilliant MH (August 1998). "A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice". Proceedings of the National Academy of Sciences of the United States of America. 95 (16): 9436–41. Bibcode:1998PNAS...95.9436L. doi:10.1073/pnas.95.16.9436. PMC 21356. PMID 9689098.
Ji Y, Walkowicz MJ, Buiting K, Johnson DK, Tarvin RE, Rinchik EM, Horsthemke B, Stubbs L, Nicholls RD (March 1999). "The ancestral gene for transcribed, low-copy repeats in the Prader-Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities". Human Molecular Genetics. 8 (3): 533–42. doi:10.1093/hmg/8.3.533. PMID 9949213.
Brilliant MH (1992). "The mouse pink-eyed dilution locus: a model for aspects of Prader-Willi syndrome, Angelman syndrome, and a form of hypomelanosis of Ito". Mammalian Genome. 3 (4): 187–91. doi:10.1007/bf00355717. PMID 1611213. S2CID 32406842.
Ji Y, Rebert NA, Joslin JM, Higgins MJ, Schultz RA, Nicholls RD (March 2000). "Structure of the highly conserved HERC2 gene and of multiple partially duplicated paralogs in human". Genome Research. 10 (3): 319–29. doi:10.1101/gr.10.3.319. PMC 311424. PMID 10720573.
Kayser M, Liu F, Janssens AC, Rivadeneira F, Lao O, van Duijn K, Vermeulen M, Arp P, Jhamai MM, van Ijcken WF, den Dunnen JT, Heath S, Zelenika D, Despriet DD, Klaver CC, Vingerling JR, de Jong PT, Hofman A, Aulchenko YS, Uitterlinden AG, Oostra BA, van Duijn CM (February 2008). "Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene". American Journal of Human Genetics. 82 (2): 411–23. doi:10.1016/j.ajhg.2007.10.003. PMC 2427174. PMID 18252221.
Lemak A, Gutmanas A, Chitayat S, Karra M, Farès C, Sunnerhagen M, Arrowsmith CH (January 2011). "A novel strategy for NMR resonance assignment and protein structure determination". Journal of Biomolecular NMR. 49 (1): 27–38. doi:10.1007/s10858-010-9458-0. PMC 3715383. PMID 21161328.
Danielsen JR, Povlsen LK, Villumsen BH, Streicher W, Nilsson J, Wikström M, Bekker-Jensen S, Mailand N (April 2012). "DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger". The Journal of Cell Biology. 197 (2): 179–87. doi:10.1083/jcb.201106152. PMC 3328386. PMID 22508508.
Branicki W, Brudnik U, Wojas-Pelc A (March 2009). "Interactions between HERC2, OCA2 and MC1R may influence human pigmentation phenotype". Annals of Human Genetics. 73 (2): 160–70. doi:10.1111/j.1469-1809.2009.00504.x. PMID 19208107. S2CID 5233533.
Eiberg H, Troelsen J, Nielsen M, Mikkelsen A, Mengel-From J, Kjaer KW, Hansen L (March 2008). "Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression". Human Genetics. 123 (2): 177–87. doi:10.1007/s00439-007-0460-x. PMID 18172690. S2CID 9886658.
Sturm RA, Larsson M (October 2009). "Genetics of human iris colour and patterns" (PDF). Pigment Cell & Melanoma Research. 22 (5): 544–62. doi:10.1111/j.1755-148X.2009.00606.x. PMID 19619260. S2CID 893259.
Sturm RA, Duffy DL, Zhao ZZ, Leite FP, Stark MS, Hayward NK, Martin NG, Montgomery GW (February 2008). "A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color". American Journal of Human Genetics. 82 (2): 424–31. doi:10.1016/j.ajhg.2007.11.005. PMC 2427173. PMID 18252222.
Donnelly MP, Paschou P, Grigorenko E, Gurwitz D, Barta C, Lu RB, Zhukova OV, Kim JJ, Siniscalco M, New M, Li H, Kajuna SL, Manolopoulos VG, Speed WC, Pakstis AJ, Kidd JR, Kidd KK (May 2012). "A global view of the OCA2-HERC2 region and pigmentation". Human Genetics. 131 (5): 683–96. doi:10.1007/s00439-011-1110-x. PMC 3325407. PMID 22065085.
Branum ME, Reardon JT, Sancar A (July 2001). "DNA repair excision nuclease attacks undamaged DNA. A potential source of spontaneous mutations". The Journal of Biological Chemistry. 276 (27): 25421–6. doi:10.1074/jbc.M101032200. PMID 11353769.
Zhu M, Zhao H, Liao J, Xu X (December 2014). "HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability". Nucleic Acids Research. 42 (21): 13074–81. doi:10.1093/nar/gku978. PMC 4245974. PMID 25326330.
Yuan J, Luo K, Deng M, Li Y, Yin P, Gao B, Fang Y, Wu P, Liu T, Lou Z (December 2014). "HERC2-USP20 axis regulates DNA damage checkpoint through Claspin". Nucleic Acids Research. 42 (21): 13110–21. doi:10.1093/nar/gku1034. PMC 4245938. PMID 25355518.
Izawa N, Wu W, Sato K, Nishikawa H, Kato A, Boku N, Itoh F, Ohta T (September 2011). "HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progression". Cancer Research. 71 (17): 5621–5. doi:10.1158/0008-5472.CAN-11-0385. PMID 21775519.
Bekker-Jensen S, Rendtlew Danielsen J, Fugger K, Gromova I, Nerstedt A, Lukas C, Bartek J, Lukas J, Mailand N (January 2010). "HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes". Nature Cell Biology. 12 (1): 80–6, sup pp 1–12. doi:10.1038/ncb2008. PMID 20023648. S2CID 9996031.
Lee TH, Park JM, Leem SH, Kang TH (January 2014). "Coordinated regulation of XPA stability by ATR and HERC2 during nucleotide excision repair". Oncogene. 33 (1): 19–25. doi:10.1038/onc.2012.539. PMID 23178497.
Kang TH, Lindsey-Boltz LA, Reardon JT, Sancar A (March 2010). "Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase". Proceedings of the National Academy of Sciences of the United States of America. 107 (11): 4890–5. Bibcode:2010PNAS..107.4890K. doi:10.1073/pnas.0915085107. PMC 2841896. PMID 20304803.
Al-Hakim AK, Bashkurov M, Gingras AC, Durocher D, Pelletier L (June 2012). "Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture". Molecular & Cellular Proteomics. 11 (6): M111.014233. doi:10.1074/mcp.M111.014233. PMC 3433907. PMID 22261722.
Moroishi T, Yamauchi T, Nishiyama M, Nakayama KI (June 2014). "HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism". The Journal of Biological Chemistry. 289 (23): 16430–41. doi:10.1074/jbc.M113.541490. PMC 4047410. PMID 24778179.
Cubillos-Rojas M, Amair-Pinedo F, Peiró-Jordán R, Bartrons R, Ventura F, Rosa JL (May 2014). "The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization". The Journal of Biological Chemistry. 289 (21): 14782–95. doi:10.1074/jbc.M113.527978. PMC 4031533. PMID 24722987.
Kühnle S, Kogel U, Glockzin S, Marquardt A, Ciechanover A, Matentzoglu K, Scheffner M (June 2011). "Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2". The Journal of Biological Chemistry. 286 (22): 19410–6. doi:10.1074/jbc.M110.205211. PMC 3103319. PMID 21493713.
Harlalka GV, Baple EL, Cross H, Kühnle S, Cubillos-Rojas M, Matentzoglu K, Patton MA, Wagner K, Coblentz R, Ford DL, Mackay DJ, Chioza BA, Scheffner M, Rosa JL, Crosby AH (February 2013). "Mutation of HERC2 causes developmental delay with Angelman-like features" (PDF). Journal of Medical Genetics. 50 (2): 65–73. doi:10.1136/jmedgenet-2012-101367. PMID 23243086. S2CID 206997462.
Puffenberger EG, Jinks RN, Wang H, Xin B, Fiorentini C, Sherman EA, Degrazio D, Shaw C, Sougnez C, Cibulskis K, Gabriel S, Kelley RI, Morton DH, Strauss KA (December 2012). "A homozygous missense mutation in HERC2 associated with global developmental delay and autism spectrum disorder". Human Mutation. 33 (12): 1639–46. doi:10.1002/humu.22237. PMID 23065719. S2CID 10372349.
Morice-Picard F, Benard G, Rezvani HR, Lasseaux E, Simon D, Moutton S, Rooryck C, Lacombe D, Baumann C, Arveiler B (January 2016). "Complete loss of function of the ubiquitin ligase HERC2 causes a severe neurodevelopmental phenotype". European Journal of Human Genetics. 25 (1): 52–58. doi:10.1038/ejhg.2016.139. PMC 5159772. PMID 27759030.
Ferguson R, Vogelsang M, Ucisik-Akkaya E, Rai K, Pilarski R, Martinez CN, Rendleman J, Kazlow E, Nagdimov K, Osman I, Klein RJ, Davidorf FH, Cebulla CM, Abdel-Rahman MH, Kirchhoff T (August 2016). "Genetic markers of pigmentation are novel risk loci for uveal melanoma". Scientific Reports. 6 (1): 31191. Bibcode:2016NatSR...631191F. doi:10.1038/srep31191. PMC 4976361. PMID 27499155.
Yoo NJ, Park SW, Lee SH (December 2011). "Frameshift mutations of ubiquitination-related genes HERC2, HERC3, TRIP12, UBE2Q1 and UBE4B in gastric and colorectal carcinomas with microsatellite instability". Pathology. 43 (7): 753–5. doi:10.1097/pat.0b013e32834c7e78. PMID 22124266.
Wu W, Sato K, Koike A, Nishikawa H, Koizumi H, Venkitaraman AR, Ohta T (August 2010). "HERC2 is an E3 ligase that targets BRCA1 for degradation". Cancer Research. 70 (15): 6384–92. doi:10.1158/0008-5472.CAN-10-1304. PMID 20631078.
Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, Asano T, Yoshimi K, Zhang CL, Matsumoto G, Ohtsuka T, Kageyama R, Kiyonari H, Shioi G, Nukina N, Hattori N, Takahashi R (September 2015). "The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway". PLOS Genetics. 11 (9): e1005503. doi:10.1371/journal.pgen.1005503. PMC 4565672. PMID 26355680.
Fu Q, Posth C (May 2, 2016). "The genetic history of Ice Age Europe". Nature. 534 (7606): 200–205. Bibcode:2016Natur.534..200F. doi:10.1038/nature17993. hdl:10211.3/198594. PMC 4943878. PMID 27135931.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Sánchez-Tena S, Cubillos-Rojas M, Schneider T, Rosa JL (May 2016). "Functional and pathological relevance of HERC family proteins: a decade later". Cellular and Molecular Life Sciences. 73 (10): 1955–68. doi:10.1007/s00018-016-2139-8. PMC 11108380. PMID 26801221. S2CID 7457614.
Lehman AL, Nakatsu Y, Ching A, Bronson RT, Oakey RJ, Keiper-Hrynko N, Finger JN, Durham-Pierre D, Horton DB, Newton JM, Lyon MF, Brilliant MH (August 1998). "A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice". Proceedings of the National Academy of Sciences of the United States of America. 95 (16): 9436–41. Bibcode:1998PNAS...95.9436L. doi:10.1073/pnas.95.16.9436. PMC 21356. PMID 9689098.
Ji Y, Rebert NA, Joslin JM, Higgins MJ, Schultz RA, Nicholls RD (March 2000). "Structure of the highly conserved HERC2 gene and of multiple partially duplicated paralogs in human". Genome Research. 10 (3): 319–29. doi:10.1101/gr.10.3.319. PMC 311424. PMID 10720573.
Kayser M, Liu F, Janssens AC, Rivadeneira F, Lao O, van Duijn K, Vermeulen M, Arp P, Jhamai MM, van Ijcken WF, den Dunnen JT, Heath S, Zelenika D, Despriet DD, Klaver CC, Vingerling JR, de Jong PT, Hofman A, Aulchenko YS, Uitterlinden AG, Oostra BA, van Duijn CM (February 2008). "Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene". American Journal of Human Genetics. 82 (2): 411–23. doi:10.1016/j.ajhg.2007.10.003. PMC 2427174. PMID 18252221.
Lemak A, Gutmanas A, Chitayat S, Karra M, Farès C, Sunnerhagen M, Arrowsmith CH (January 2011). "A novel strategy for NMR resonance assignment and protein structure determination". Journal of Biomolecular NMR. 49 (1): 27–38. doi:10.1007/s10858-010-9458-0. PMC 3715383. PMID 21161328.
Danielsen JR, Povlsen LK, Villumsen BH, Streicher W, Nilsson J, Wikström M, Bekker-Jensen S, Mailand N (April 2012). "DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger". The Journal of Cell Biology. 197 (2): 179–87. doi:10.1083/jcb.201106152. PMC 3328386. PMID 22508508.
Sturm RA, Duffy DL, Zhao ZZ, Leite FP, Stark MS, Hayward NK, Martin NG, Montgomery GW (February 2008). "A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color". American Journal of Human Genetics. 82 (2): 424–31. doi:10.1016/j.ajhg.2007.11.005. PMC 2427173. PMID 18252222.
Donnelly MP, Paschou P, Grigorenko E, Gurwitz D, Barta C, Lu RB, Zhukova OV, Kim JJ, Siniscalco M, New M, Li H, Kajuna SL, Manolopoulos VG, Speed WC, Pakstis AJ, Kidd JR, Kidd KK (May 2012). "A global view of the OCA2-HERC2 region and pigmentation". Human Genetics. 131 (5): 683–96. doi:10.1007/s00439-011-1110-x. PMC 3325407. PMID 22065085.
Zhu M, Zhao H, Liao J, Xu X (December 2014). "HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability". Nucleic Acids Research. 42 (21): 13074–81. doi:10.1093/nar/gku978. PMC 4245974. PMID 25326330.
Yuan J, Luo K, Deng M, Li Y, Yin P, Gao B, Fang Y, Wu P, Liu T, Lou Z (December 2014). "HERC2-USP20 axis regulates DNA damage checkpoint through Claspin". Nucleic Acids Research. 42 (21): 13110–21. doi:10.1093/nar/gku1034. PMC 4245938. PMID 25355518.
Kang TH, Lindsey-Boltz LA, Reardon JT, Sancar A (March 2010). "Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase". Proceedings of the National Academy of Sciences of the United States of America. 107 (11): 4890–5. Bibcode:2010PNAS..107.4890K. doi:10.1073/pnas.0915085107. PMC 2841896. PMID 20304803.
Al-Hakim AK, Bashkurov M, Gingras AC, Durocher D, Pelletier L (June 2012). "Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture". Molecular & Cellular Proteomics. 11 (6): M111.014233. doi:10.1074/mcp.M111.014233. PMC 3433907. PMID 22261722.
Moroishi T, Yamauchi T, Nishiyama M, Nakayama KI (June 2014). "HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism". The Journal of Biological Chemistry. 289 (23): 16430–41. doi:10.1074/jbc.M113.541490. PMC 4047410. PMID 24778179.
Cubillos-Rojas M, Amair-Pinedo F, Peiró-Jordán R, Bartrons R, Ventura F, Rosa JL (May 2014). "The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization". The Journal of Biological Chemistry. 289 (21): 14782–95. doi:10.1074/jbc.M113.527978. PMC 4031533. PMID 24722987.
Kühnle S, Kogel U, Glockzin S, Marquardt A, Ciechanover A, Matentzoglu K, Scheffner M (June 2011). "Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2". The Journal of Biological Chemistry. 286 (22): 19410–6. doi:10.1074/jbc.M110.205211. PMC 3103319. PMID 21493713.
Morice-Picard F, Benard G, Rezvani HR, Lasseaux E, Simon D, Moutton S, Rooryck C, Lacombe D, Baumann C, Arveiler B (January 2016). "Complete loss of function of the ubiquitin ligase HERC2 causes a severe neurodevelopmental phenotype". European Journal of Human Genetics. 25 (1): 52–58. doi:10.1038/ejhg.2016.139. PMC 5159772. PMID 27759030.
Ferguson R, Vogelsang M, Ucisik-Akkaya E, Rai K, Pilarski R, Martinez CN, Rendleman J, Kazlow E, Nagdimov K, Osman I, Klein RJ, Davidorf FH, Cebulla CM, Abdel-Rahman MH, Kirchhoff T (August 2016). "Genetic markers of pigmentation are novel risk loci for uveal melanoma". Scientific Reports. 6 (1): 31191. Bibcode:2016NatSR...631191F. doi:10.1038/srep31191. PMC 4976361. PMID 27499155.
Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, Asano T, Yoshimi K, Zhang CL, Matsumoto G, Ohtsuka T, Kageyama R, Kiyonari H, Shioi G, Nukina N, Hattori N, Takahashi R (September 2015). "The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway". PLOS Genetics. 11 (9): e1005503. doi:10.1371/journal.pgen.1005503. PMC 4565672. PMID 26355680.
Fu Q, Posth C (May 2, 2016). "The genetic history of Ice Age Europe". Nature. 534 (7606): 200–205. Bibcode:2016Natur.534..200F. doi:10.1038/nature17993. hdl:10211.3/198594. PMC 4943878. PMID 27135931.

semanticscholar.org

api.semanticscholar.org

Sánchez-Tena S, Cubillos-Rojas M, Schneider T, Rosa JL (May 2016). "Functional and pathological relevance of HERC family proteins: a decade later". Cellular and Molecular Life Sciences. 73 (10): 1955–68. doi:10.1007/s00018-016-2139-8. PMC 11108380. PMID 26801221. S2CID 7457614.
Brilliant MH (1992). "The mouse pink-eyed dilution locus: a model for aspects of Prader-Willi syndrome, Angelman syndrome, and a form of hypomelanosis of Ito". Mammalian Genome. 3 (4): 187–91. doi:10.1007/bf00355717. PMID 1611213. S2CID 32406842.
Branicki W, Brudnik U, Wojas-Pelc A (March 2009). "Interactions between HERC2, OCA2 and MC1R may influence human pigmentation phenotype". Annals of Human Genetics. 73 (2): 160–70. doi:10.1111/j.1469-1809.2009.00504.x. PMID 19208107. S2CID 5233533.
Eiberg H, Troelsen J, Nielsen M, Mikkelsen A, Mengel-From J, Kjaer KW, Hansen L (March 2008). "Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression". Human Genetics. 123 (2): 177–87. doi:10.1007/s00439-007-0460-x. PMID 18172690. S2CID 9886658.
Sturm RA, Larsson M (October 2009). "Genetics of human iris colour and patterns" (PDF). Pigment Cell & Melanoma Research. 22 (5): 544–62. doi:10.1111/j.1755-148X.2009.00606.x. PMID 19619260. S2CID 893259.
Bekker-Jensen S, Rendtlew Danielsen J, Fugger K, Gromova I, Nerstedt A, Lukas C, Bartek J, Lukas J, Mailand N (January 2010). "HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes". Nature Cell Biology. 12 (1): 80–6, sup pp 1–12. doi:10.1038/ncb2008. PMID 20023648. S2CID 9996031.
Harlalka GV, Baple EL, Cross H, Kühnle S, Cubillos-Rojas M, Matentzoglu K, Patton MA, Wagner K, Coblentz R, Ford DL, Mackay DJ, Chioza BA, Scheffner M, Rosa JL, Crosby AH (February 2013). "Mutation of HERC2 causes developmental delay with Angelman-like features" (PDF). Journal of Medical Genetics. 50 (2): 65–73. doi:10.1136/jmedgenet-2012-101367. PMID 23243086. S2CID 206997462.
Puffenberger EG, Jinks RN, Wang H, Xin B, Fiorentini C, Sherman EA, Degrazio D, Shaw C, Sougnez C, Cibulskis K, Gabriel S, Kelley RI, Morton DH, Strauss KA (December 2012). "A homozygous missense mutation in HERC2 associated with global developmental delay and autism spectrum disorder". Human Mutation. 33 (12): 1639–46. doi:10.1002/humu.22237. PMID 23065719. S2CID 10372349.

uni-konstanz.de

kops.uni-konstanz.de

Harlalka GV, Baple EL, Cross H, Kühnle S, Cubillos-Rojas M, Matentzoglu K, Patton MA, Wagner K, Coblentz R, Ford DL, Mackay DJ, Chioza BA, Scheffner M, Rosa JL, Crosby AH (February 2013). "Mutation of HERC2 causes developmental delay with Angelman-like features" (PDF). Journal of Medical Genetics. 50 (2): 65–73. doi:10.1136/jmedgenet-2012-101367. PMID 23243086. S2CID 206997462.

web.archive.org

Bryner J (2008-01-31). "Here's what made those brown eyes blue". Health News. NBC News. Retrieved 2008-11-06.; Bryner J (2008-01-31). "One Common Ancestor Behind Blue Eyes". LiveScience. Imaginova Corp. Retrieved 2008-11-06.; "Blue-eyed humans have a single, common ancestor". News. University of Copenhagen. 2008-01-30. Archived from the original on 2008-11-08. Retrieved 2008-11-06.

yale.edu

alfred.med.yale.edu

"Allele Frequency For Polymorphic Site: rs916977". ALFRED. Retrieved 22 June 2016.