HMG-CoA reductase (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "HMG-CoA reductase" in English language version.

refsWebsite

Global rank English rank

49nih.gov

4^th place

32doi.org

2^nd place

5harvard.edu

18^th place

17^th place

5semanticscholar.org

11^th place

8^th place

2ensembl.org

1,626^th place

1,007^th place

1wikipathways.org

low place

1ntu.edu.tw

2,798^th place

4,271^st place

1handle.net

102^nd place

76^th place

doi.org

Roitelman J, Olender EH, Bar-Nun S, Dunn WA, Simoni RD (June 1992). "Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum". The Journal of Cell Biology. 117 (5): 959–973. doi:10.1083/jcb.117.5.959. PMC 2289486. PMID 1374417.
Lindgren V, Luskey KL, Russell DW, Francke U (December 1985). "Human genes involved in cholesterol metabolism: chromosomal mapping of the loci for the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase with cDNA probes". Proceedings of the National Academy of Sciences of the United States of America. 82 (24): 8567–8571. Bibcode:1985PNAS...82.8567L. doi:10.1073/pnas.82.24.8567. PMC 390958. PMID 3866240.
Brown MS, Radhakrishnan A, Goldstein JL (June 2018). "Retrospective on Cholesterol Homeostasis: The Central Role of Scap". Annual Review of Biochemistry. 87: 783–807. doi:10.1146/annurev-biochem-062917-011852. PMC 5828883. PMID 28841344.
Radhakrishnan A, Sun LP, Kwon HJ, Brown MS, Goldstein JL (July 2004). "Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain". Molecular Cell. 15 (2): 259–268. doi:10.1016/j.molcel.2004.06.019. PMID 15260976.
Costa CH, Oliveira AR, Dos Santos AM, da Costa KS, Lima AH, Alves CN, Lameira J (October 2019). "Computational study of conformational changes in human 3-hydroxy-3-methylglutaryl coenzyme reductase induced by substrate binding". Journal of Biomolecular Structure & Dynamics. 37 (16): 4374–4383. doi:10.1080/07391102.2018.1549508. PMID 30470158. S2CID 53717806.
Farmer JA (1998). "Aggressive lipid therapy in the statin era". Progress in Cardiovascular Diseases. 41 (2): 71–94. doi:10.1016/S0033-0620(98)80006-6. PMID 9790411.
Lin YL, Wang TH, Lee MH, Su NW (January 2008). "Biologically active components and nutraceuticals in the Monascus-fermented rice: a review" (PDF). Applied Microbiology and Biotechnology. 77 (5): 965–973. doi:10.1007/s00253-007-1256-6. PMID 18038131. S2CID 33299544.
Han KH (November 2018). "Functional Implications of HMG-CoA Reductase Inhibition on Glucose Metabolism". Korean Circulation Journal. 48 (11). The Korean Society of Cardiology: 951–963. doi:10.4070/kcj.2018.0307. PMC 6196158. PMID 30334382.
Hardie DG (February 1992). "Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase". Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1123 (3): 231–238. doi:10.1016/0005-2760(92)90001-c. PMID 1536860.
Arnaud C, Veillard NR, Mach F (April 2005). "Cholesterol-independent effects of statins in inflammation, immunomodulation and atherosclerosis". Current Drug Targets - Cardiovascular & Hematological Disorders. 5 (2): 127–134. doi:10.2174/1568006043586198. PMID 15853754.
Sorrentino S, Landmesser U (December 2005). "Nonlipid-lowering effects of statins". Current Treatment Options in Cardiovascular Medicine. 7 (6): 459–466. doi:10.1007/s11936-005-0031-1. PMID 16283973. S2CID 44918429.
Stüve O, Youssef S, Steinman L, Zamvil SS (June 2003). "Statins as potential therapeutic agents in neuroinflammatory disorders". Current Opinion in Neurology. 16 (3): 393–401. doi:10.1097/00019052-200306000-00021. PMID 12858078.
Mashayekhi-Sardoo H, Atkin SL, Montecucco F, Sahebkar A (2021). "Potential Alteration of Statin-Related Pharmacological Features in Diabetes Mellitus". BioMed Research International. 2021: 6698743. doi:10.1155/2021/6698743. PMC 8018846. PMID 33834073.
Thorpe JL, Doitsidou M, Ho SY, Raz E, Farber SA (February 2004). "Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation". Developmental Cell. 6 (2): 295–302. doi:10.1016/S1534-5807(04)00032-2. hdl:11858/00-001M-0000-0012-EE5B-7. PMID 14960282.
Eisa-Beygi S, Hatch G, Noble S, Ekker M, Moon TW (January 2013). "The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway". Developmental Biology. 373 (2): 258–266. doi:10.1016/j.ydbio.2012.11.024. PMID 23206891.
Yogev Y, Shorer Z, Koifman A, Wormser O, Drabkin M, Halperin D, Dolgin V, Proskorovski-Ohayon R, Hadar N, Davidov G, Nudelman H, Zarivach R, Shelef I, Perez Y, Birk OS (February 2023). "Limb girdle muscular disease caused by HMGCR mutation and statin myopathy treatable with mevalonolactone". Proc Natl Acad Sci U S A. 120 (7): e2217831120. Bibcode:2023PNAS..12017831Y. doi:10.1073/pnas.2217831120. PMC 9963716. PMID 36745799.
Thompson PD, Panza G, Zaleski A, Taylor B (May 2016). "Statin-Associated Side Effects". Journal of the American College of Cardiology (Review). 67 (20): 2395–2410. doi:10.1016/j.jacc.2016.02.071. PMID 27199064.
Mammen AL (February 2016). "Statin-Associated Autoimmune Myopathy". The New England Journal of Medicine (Review). 374 (7): 664–669. doi:10.1056/NEJMra1515161. PMID 26886523.
Sun LP, Seemann J, Goldstein JL, Brown MS (April 2007). "Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins". Proceedings of the National Academy of Sciences of the United States of America. 104 (16): 6519–6526. Bibcode:2007PNAS..104.6519S. doi:10.1073/pnas.0700907104. PMC 1851663. PMID 17428919.
Sun LP, Li L, Goldstein JL, Brown MS (July 2005). "Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro". The Journal of Biological Chemistry. 280 (28): 26483–26490. doi:10.1074/jbc.M504041200. PMID 15899885.
Meigs TE, Roseman DS, Simoni RD (April 1996). "Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo". The Journal of Biological Chemistry. 271 (14): 7916–7922. doi:10.1074/jbc.271.14.7916. PMID 8626470.
Meigs TE, Simoni RD (September 1997). "Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase". Archives of Biochemistry and Biophysics. 345 (1): 1–9. doi:10.1006/abbi.1997.0200. PMID 9281305.
Keller RK, Zhao Z, Chambers C, Ness GC (April 1996). "Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver". Archives of Biochemistry and Biophysics. 328 (2): 324–330. doi:10.1006/abbi.1996.0180. PMID 8645011.
Song BL, Sever N, DeBose-Boyd RA (September 2005). "Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase". Molecular Cell. 19 (6): 829–840. doi:10.1016/j.molcel.2005.08.009. PMID 16168377.
Jo Y, Lee PC, Sguigna PV, DeBose-Boyd RA (December 2011). "Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8". Proceedings of the National Academy of Sciences of the United States of America. 108 (51): 20503–20508. Bibcode:2011PNAS..10820503J. doi:10.1073/pnas.1112831108. PMC 3251157. PMID 22143767.
Jiang LY, Jiang W, Tian N, Xiong YN, Liu J, Wei J, et al. (March 2018). "Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase". The Journal of Biological Chemistry. 293 (11): 4047–4055. doi:10.1074/jbc.RA117.001260. PMC 5857978. PMID 29374057.
Menzies SA, Volkmar N, van den Boomen DJ, Timms RT, Dickson AS, Nathan JA, Lehner PJ (December 2018). "The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1". eLife. 7. doi:10.7554/eLife.40009. PMC 6292692. PMID 30543180.
Tsai YC, Leichner GS, Pearce MM, Wilson GL, Wojcikiewicz RJ, Roitelman J, Weissman AM (December 2012). "Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system". Molecular Biology of the Cell. 23 (23): 4484–4494. doi:10.1091/mbc.E12-08-0631. PMC 3510011. PMID 23087214.
Istvan ES, Palnitkar M, Buchanan SK, Deisenhofer J (March 2000). "Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis". The EMBO Journal. 19 (5): 819–830. doi:10.1093/emboj/19.5.819. PMC 305622. PMID 10698924.
Goldstein JL, Brown MS (February 1990). "Regulation of the mevalonate pathway". Nature. 343 (6257): 425–430. Bibcode:1990Natur.343..425G. doi:10.1038/343425a0. PMID 1967820. S2CID 30477478.
Hardie DG, Scott JW, Pan DA, Hudson ER (July 2003). "Management of cellular energy by the AMP-activated protein kinase system". FEBS Letters. 546 (1): 113–120. doi:10.1016/S0014-5793(03)00560-X. PMID 12829246. S2CID 42881381.
Witters LA, Kemp BE, Means AR (January 2006). "Chutes and Ladders: the search for protein kinases that act on AMPK". Trends in Biochemical Sciences. 31 (1): 13–16. doi:10.1016/j.tibs.2005.11.009. PMID 16356723.

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000113161 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000021670 – Ensembl, May 2017

handle.net

hdl.handle.net

Thorpe JL, Doitsidou M, Ho SY, Raz E, Farber SA (February 2004). "Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation". Developmental Cell. 6 (2): 295–302. doi:10.1016/S1534-5807(04)00032-2. hdl:11858/00-001M-0000-0012-EE5B-7. PMID 14960282.

harvard.edu

ui.adsabs.harvard.edu

Lindgren V, Luskey KL, Russell DW, Francke U (December 1985). "Human genes involved in cholesterol metabolism: chromosomal mapping of the loci for the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase with cDNA probes". Proceedings of the National Academy of Sciences of the United States of America. 82 (24): 8567–8571. Bibcode:1985PNAS...82.8567L. doi:10.1073/pnas.82.24.8567. PMC 390958. PMID 3866240.
Yogev Y, Shorer Z, Koifman A, Wormser O, Drabkin M, Halperin D, Dolgin V, Proskorovski-Ohayon R, Hadar N, Davidov G, Nudelman H, Zarivach R, Shelef I, Perez Y, Birk OS (February 2023). "Limb girdle muscular disease caused by HMGCR mutation and statin myopathy treatable with mevalonolactone". Proc Natl Acad Sci U S A. 120 (7): e2217831120. Bibcode:2023PNAS..12017831Y. doi:10.1073/pnas.2217831120. PMC 9963716. PMID 36745799.
Sun LP, Seemann J, Goldstein JL, Brown MS (April 2007). "Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins". Proceedings of the National Academy of Sciences of the United States of America. 104 (16): 6519–6526. Bibcode:2007PNAS..104.6519S. doi:10.1073/pnas.0700907104. PMC 1851663. PMID 17428919.
Jo Y, Lee PC, Sguigna PV, DeBose-Boyd RA (December 2011). "Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8". Proceedings of the National Academy of Sciences of the United States of America. 108 (51): 20503–20508. Bibcode:2011PNAS..10820503J. doi:10.1073/pnas.1112831108. PMC 3251157. PMID 22143767.
Goldstein JL, Brown MS (February 1990). "Regulation of the mevalonate pathway". Nature. 343 (6257): 425–430. Bibcode:1990Natur.343..425G. doi:10.1038/343425a0. PMID 1967820. S2CID 30477478.

nih.gov

pubmed.ncbi.nlm.nih.gov

Roitelman J, Olender EH, Bar-Nun S, Dunn WA, Simoni RD (June 1992). "Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum". The Journal of Cell Biology. 117 (5): 959–973. doi:10.1083/jcb.117.5.959. PMC 2289486. PMID 1374417.
Lindgren V, Luskey KL, Russell DW, Francke U (December 1985). "Human genes involved in cholesterol metabolism: chromosomal mapping of the loci for the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase with cDNA probes". Proceedings of the National Academy of Sciences of the United States of America. 82 (24): 8567–8571. Bibcode:1985PNAS...82.8567L. doi:10.1073/pnas.82.24.8567. PMC 390958. PMID 3866240.
Brown MS, Radhakrishnan A, Goldstein JL (June 2018). "Retrospective on Cholesterol Homeostasis: The Central Role of Scap". Annual Review of Biochemistry. 87: 783–807. doi:10.1146/annurev-biochem-062917-011852. PMC 5828883. PMID 28841344.
Radhakrishnan A, Sun LP, Kwon HJ, Brown MS, Goldstein JL (July 2004). "Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain". Molecular Cell. 15 (2): 259–268. doi:10.1016/j.molcel.2004.06.019. PMID 15260976.
Costa CH, Oliveira AR, Dos Santos AM, da Costa KS, Lima AH, Alves CN, Lameira J (October 2019). "Computational study of conformational changes in human 3-hydroxy-3-methylglutaryl coenzyme reductase induced by substrate binding". Journal of Biomolecular Structure & Dynamics. 37 (16): 4374–4383. doi:10.1080/07391102.2018.1549508. PMID 30470158. S2CID 53717806.
Farmer JA (1998). "Aggressive lipid therapy in the statin era". Progress in Cardiovascular Diseases. 41 (2): 71–94. doi:10.1016/S0033-0620(98)80006-6. PMID 9790411.
"Is there a "best" statin drug?". The Johns Hopkins Medical Letter Health After 50. 15 (11): 4–5. January 2004. PMID 14983817.
Lin YL, Wang TH, Lee MH, Su NW (January 2008). "Biologically active components and nutraceuticals in the Monascus-fermented rice: a review" (PDF). Applied Microbiology and Biotechnology. 77 (5): 965–973. doi:10.1007/s00253-007-1256-6. PMID 18038131. S2CID 33299544.
Flores NA (September 2004). "Ezetimibe + simvastatin (Merck/Schering-Plough)". Current Opinion in Investigational Drugs. 5 (9): 984–992. PMID 15503655.
Han KH (November 2018). "Functional Implications of HMG-CoA Reductase Inhibition on Glucose Metabolism". Korean Circulation Journal. 48 (11). The Korean Society of Cardiology: 951–963. doi:10.4070/kcj.2018.0307. PMC 6196158. PMID 30334382.
Hardie DG (February 1992). "Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase". Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1123 (3): 231–238. doi:10.1016/0005-2760(92)90001-c. PMID 1536860.
Arnaud C, Veillard NR, Mach F (April 2005). "Cholesterol-independent effects of statins in inflammation, immunomodulation and atherosclerosis". Current Drug Targets - Cardiovascular & Hematological Disorders. 5 (2): 127–134. doi:10.2174/1568006043586198. PMID 15853754.
Sorrentino S, Landmesser U (December 2005). "Nonlipid-lowering effects of statins". Current Treatment Options in Cardiovascular Medicine. 7 (6): 459–466. doi:10.1007/s11936-005-0031-1. PMID 16283973. S2CID 44918429.
Stüve O, Youssef S, Steinman L, Zamvil SS (June 2003). "Statins as potential therapeutic agents in neuroinflammatory disorders". Current Opinion in Neurology. 16 (3): 393–401. doi:10.1097/00019052-200306000-00021. PMID 12858078.
Mashayekhi-Sardoo H, Atkin SL, Montecucco F, Sahebkar A (2021). "Potential Alteration of Statin-Related Pharmacological Features in Diabetes Mellitus". BioMed Research International. 2021: 6698743. doi:10.1155/2021/6698743. PMC 8018846. PMID 33834073.
Thorpe JL, Doitsidou M, Ho SY, Raz E, Farber SA (February 2004). "Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation". Developmental Cell. 6 (2): 295–302. doi:10.1016/S1534-5807(04)00032-2. hdl:11858/00-001M-0000-0012-EE5B-7. PMID 14960282.
Eisa-Beygi S, Hatch G, Noble S, Ekker M, Moon TW (January 2013). "The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway". Developmental Biology. 373 (2): 258–266. doi:10.1016/j.ydbio.2012.11.024. PMID 23206891.
Yogev Y, Shorer Z, Koifman A, Wormser O, Drabkin M, Halperin D, Dolgin V, Proskorovski-Ohayon R, Hadar N, Davidov G, Nudelman H, Zarivach R, Shelef I, Perez Y, Birk OS (February 2023). "Limb girdle muscular disease caused by HMGCR mutation and statin myopathy treatable with mevalonolactone". Proc Natl Acad Sci U S A. 120 (7): e2217831120. Bibcode:2023PNAS..12017831Y. doi:10.1073/pnas.2217831120. PMC 9963716. PMID 36745799.
Thompson PD, Panza G, Zaleski A, Taylor B (May 2016). "Statin-Associated Side Effects". Journal of the American College of Cardiology (Review). 67 (20): 2395–2410. doi:10.1016/j.jacc.2016.02.071. PMID 27199064.
Mammen AL (February 2016). "Statin-Associated Autoimmune Myopathy". The New England Journal of Medicine (Review). 374 (7): 664–669. doi:10.1056/NEJMra1515161. PMID 26886523.
Sun LP, Seemann J, Goldstein JL, Brown MS (April 2007). "Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins". Proceedings of the National Academy of Sciences of the United States of America. 104 (16): 6519–6526. Bibcode:2007PNAS..104.6519S. doi:10.1073/pnas.0700907104. PMC 1851663. PMID 17428919.
Sun LP, Li L, Goldstein JL, Brown MS (July 2005). "Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro". The Journal of Biological Chemistry. 280 (28): 26483–26490. doi:10.1074/jbc.M504041200. PMID 15899885.
Meigs TE, Roseman DS, Simoni RD (April 1996). "Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo". The Journal of Biological Chemistry. 271 (14): 7916–7922. doi:10.1074/jbc.271.14.7916. PMID 8626470.
Meigs TE, Simoni RD (September 1997). "Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase". Archives of Biochemistry and Biophysics. 345 (1): 1–9. doi:10.1006/abbi.1997.0200. PMID 9281305.
Keller RK, Zhao Z, Chambers C, Ness GC (April 1996). "Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver". Archives of Biochemistry and Biophysics. 328 (2): 324–330. doi:10.1006/abbi.1996.0180. PMID 8645011.
Song BL, Sever N, DeBose-Boyd RA (September 2005). "Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase". Molecular Cell. 19 (6): 829–840. doi:10.1016/j.molcel.2005.08.009. PMID 16168377.
Jo Y, Lee PC, Sguigna PV, DeBose-Boyd RA (December 2011). "Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8". Proceedings of the National Academy of Sciences of the United States of America. 108 (51): 20503–20508. Bibcode:2011PNAS..10820503J. doi:10.1073/pnas.1112831108. PMC 3251157. PMID 22143767.
Jiang LY, Jiang W, Tian N, Xiong YN, Liu J, Wei J, et al. (March 2018). "Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase". The Journal of Biological Chemistry. 293 (11): 4047–4055. doi:10.1074/jbc.RA117.001260. PMC 5857978. PMID 29374057.
Menzies SA, Volkmar N, van den Boomen DJ, Timms RT, Dickson AS, Nathan JA, Lehner PJ (December 2018). "The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1". eLife. 7. doi:10.7554/eLife.40009. PMC 6292692. PMID 30543180.
Tsai YC, Leichner GS, Pearce MM, Wilson GL, Wojcikiewicz RJ, Roitelman J, Weissman AM (December 2012). "Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system". Molecular Biology of the Cell. 23 (23): 4484–4494. doi:10.1091/mbc.E12-08-0631. PMC 3510011. PMID 23087214.
Istvan ES, Palnitkar M, Buchanan SK, Deisenhofer J (March 2000). "Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis". The EMBO Journal. 19 (5): 819–830. doi:10.1093/emboj/19.5.819. PMC 305622. PMID 10698924.
Goldstein JL, Brown MS (February 1990). "Regulation of the mevalonate pathway". Nature. 343 (6257): 425–430. Bibcode:1990Natur.343..425G. doi:10.1038/343425a0. PMID 1967820. S2CID 30477478.
Hardie DG, Scott JW, Pan DA, Hudson ER (July 2003). "Management of cellular energy by the AMP-activated protein kinase system". FEBS Letters. 546 (1): 113–120. doi:10.1016/S0014-5793(03)00560-X. PMID 12829246. S2CID 42881381.
Witters LA, Kemp BE, Means AR (January 2006). "Chutes and Ladders: the search for protein kinases that act on AMPK". Trends in Biochemical Sciences. 31 (1): 13–16. doi:10.1016/j.tibs.2005.11.009. PMID 16356723.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Roitelman J, Olender EH, Bar-Nun S, Dunn WA, Simoni RD (June 1992). "Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum". The Journal of Cell Biology. 117 (5): 959–973. doi:10.1083/jcb.117.5.959. PMC 2289486. PMID 1374417.
Lindgren V, Luskey KL, Russell DW, Francke U (December 1985). "Human genes involved in cholesterol metabolism: chromosomal mapping of the loci for the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase with cDNA probes". Proceedings of the National Academy of Sciences of the United States of America. 82 (24): 8567–8571. Bibcode:1985PNAS...82.8567L. doi:10.1073/pnas.82.24.8567. PMC 390958. PMID 3866240.
Brown MS, Radhakrishnan A, Goldstein JL (June 2018). "Retrospective on Cholesterol Homeostasis: The Central Role of Scap". Annual Review of Biochemistry. 87: 783–807. doi:10.1146/annurev-biochem-062917-011852. PMC 5828883. PMID 28841344.
"Entrez Gene: HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase".
Han KH (November 2018). "Functional Implications of HMG-CoA Reductase Inhibition on Glucose Metabolism". Korean Circulation Journal. 48 (11). The Korean Society of Cardiology: 951–963. doi:10.4070/kcj.2018.0307. PMC 6196158. PMID 30334382.
Mashayekhi-Sardoo H, Atkin SL, Montecucco F, Sahebkar A (2021). "Potential Alteration of Statin-Related Pharmacological Features in Diabetes Mellitus". BioMed Research International. 2021: 6698743. doi:10.1155/2021/6698743. PMC 8018846. PMID 33834073.
Yogev Y, Shorer Z, Koifman A, Wormser O, Drabkin M, Halperin D, Dolgin V, Proskorovski-Ohayon R, Hadar N, Davidov G, Nudelman H, Zarivach R, Shelef I, Perez Y, Birk OS (February 2023). "Limb girdle muscular disease caused by HMGCR mutation and statin myopathy treatable with mevalonolactone". Proc Natl Acad Sci U S A. 120 (7): e2217831120. Bibcode:2023PNAS..12017831Y. doi:10.1073/pnas.2217831120. PMC 9963716. PMID 36745799.
Sun LP, Seemann J, Goldstein JL, Brown MS (April 2007). "Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins". Proceedings of the National Academy of Sciences of the United States of America. 104 (16): 6519–6526. Bibcode:2007PNAS..104.6519S. doi:10.1073/pnas.0700907104. PMC 1851663. PMID 17428919.
Jo Y, Lee PC, Sguigna PV, DeBose-Boyd RA (December 2011). "Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8". Proceedings of the National Academy of Sciences of the United States of America. 108 (51): 20503–20508. Bibcode:2011PNAS..10820503J. doi:10.1073/pnas.1112831108. PMC 3251157. PMID 22143767.
Jiang LY, Jiang W, Tian N, Xiong YN, Liu J, Wei J, et al. (March 2018). "Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase". The Journal of Biological Chemistry. 293 (11): 4047–4055. doi:10.1074/jbc.RA117.001260. PMC 5857978. PMID 29374057.
Menzies SA, Volkmar N, van den Boomen DJ, Timms RT, Dickson AS, Nathan JA, Lehner PJ (December 2018). "The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1". eLife. 7. doi:10.7554/eLife.40009. PMC 6292692. PMID 30543180.
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The interactive pathway map can be edited at WikiPathways: "Statin_Pathway_WP430".