Heparin (English Wikipedia)

Francis CW, Kaplan KL (2006). "Chapter 21. Principles of Antithrombotic Therapy". In Lichtman MA, Beutler E, Kipps TJ, et al. (eds.). Williams Hematology (7th ed.). McGraw-Hill Companies,Incorporated. ISBN 978-0-07-143591-8. Archived from the original on 7 July 2011.

afr.com

Margo J (19 January 2022). "A 70-year-old drug may be the answer to treating COVID-19". The Australian Financial Review. Archived from the original on 22 January 2022. Retrieved 22 January 2022.

amh.net.au

amhonline.amh.net.au

Australian Medicines Handbook (2019 (online) ed.). Adelaide: Australian Medicines Handbook Pty Ltd. January 2019.

animalresearch.info

"Heparin used as an anticoagulant". AnimalResearch.info. Archived from the original on 23 October 2013.

archive.org

Cox M, Nelson D (2004). Lehninger, Principles of Biochemistry. Freeman. p. 254. ISBN 978-0-7167-4339-2.
Xiong S, Zhang L, He QY (2008). "Fractionation of proteins by heparin chromatography". 2D PAGE: Sample Preparation and Fractionation. Methods in Molecular Biology. Vol. 424. pp. 213–21. doi:10.1007/978-1-60327-064-9_18. ISBN 978-1-58829-722-8. PMID 18369865.

archive.today

"Online Medical Dictionary". Centre for Cancer Education. 2000. Archived from the original on 13 August 2007. Retrieved 11 July 2008.

biolbull.org

Hovingh P, Linker A (October 1993). "Glycosaminoglycans in Anodonta californiensis, a Freshwater Mussel". The Biological Bulletin. 185 (2): 263–276. doi:10.2307/1542006. JSTOR 1542006. PMID 27768418. S2CID 42108805. Archived from the original on 27 September 2007. Retrieved 22 March 2007.

books.google.com

McClatchey KD (2002). Clinical Laboratory Medicine. Lippincott Williams & Wilkins. p. 662. ISBN 978-0-683-30751-1. Archived from the original on 10 September 2017.
Li JL, Corey EJ (2013). Drug Discovery: Practices, Processes, and Perspectives. John Wiley & Sons. p. 189. ISBN 978-1-118-35446-9. Archived from the original on 10 September 2017.
Rietschel RL, Fowler JF, Fisher AA (2008). Fisher's Contact Dermatitis. PMPH-USA. p. 142. ISBN 978-1-55009-378-0. Archived from the original on 10 September 2017.

cbsnews.com

CBS News. "Blood-thinning drug under suspicion". Archived from the original on 23 October 2012.

cnn.com

Ornstein C, Gorman A (21 November 2007). "Report: Dennis Quaid's twins get accidental overdose". Los Angeles Times. Archived from the original on 7 March 2008.

covid19-sciencetable.ca

Pai M, Grill A, Ivers N (26 March 2021). "Vaccine-Induced Prothrombotic Immune Thrombocytopenia (VIPIT) Following AstraZeneca COVID-19 Vaccination" (PDF). The Ontario COVID-19 Science Advisory Table. doi:10.47326/ocsat.2021.02.17.1.0. S2CID 233663558. Archived (PDF) from the original on 30 March 2021. Retrieved 3 April 2021. {{cite journal}}: Cite journal requires |journal= (help)

dallasnews.com

"At a Glance Heparin Overdose at Hospital". Dallas Morning News. 11 July 2008. Archived from the original on 25 October 2008.

dgho.de

"AstraZeneca COVID-19-Vakzine Umgang mit dem Risiko von Gerinnungskomplikationen" (PDF). Archived (PDF) from the original on 13 January 2024. Retrieved 3 April 2021.

doi.org

Alquwaizani M, Buckley L, Adams C, Fanikos J (June 2013). "Anticoagulants: A Review of the Pharmacology, Dosing, and Complications". Current Emergency and Hospital Medicine Reports. 1 (2): 83–97. doi:10.1007/s40138-013-0014-6. PMC 3654192. PMID 23687625.
Greinacher A, Thiele T, Warkentin TE, Weisser K, Kyrle PA, Eichinger S (June 2021). "Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination". The New England Journal of Medicine. 384 (22): 2092–2101. doi:10.1056/NEJMoa2104840. PMC 8095372. PMID 33835769.
Pai M, Grill A, Ivers N (26 March 2021). "Vaccine-Induced Prothrombotic Immune Thrombocytopenia (VIPIT) Following AstraZeneca COVID-19 Vaccination" (PDF). The Ontario COVID-19 Science Advisory Table. doi:10.47326/ocsat.2021.02.17.1.0. S2CID 233663558. Archived (PDF) from the original on 30 March 2021. Retrieved 3 April 2021. {{cite journal}}: Cite journal requires |journal= (help)
McLEAN J (January 1959). "The discovery of heparin". Circulation. 19 (1): 75–8. doi:10.1161/01.CIR.19.1.75. PMID 13619023.
Mueller RL, Scheidt S (January 1994). "History of drugs for thrombotic disease. Discovery, development, and directions for the future". Circulation. 89 (1): 432–49. doi:10.1161/01.cir.89.1.432. PMID 8281678.
Jorpes E (August 1935). "The chemistry of heparin". The Biochemical Journal. 29 (8): 1817–30. doi:10.1042/bj0291817. PMC 1266692. PMID 16745848.
Prinz B (April 2022). "How blood met plastics, plant and animal extracts: Material encounters between medicine and industry in the twentieth century". Studies in History and Philosophy of Science. 92: 45–55. doi:10.1016/j.shpsa.2022.01.007. PMID 35131685. S2CID 246575794.
Agnelli G, Piovella F, Buoncristiani P, Severi P, Pini M, D'Angelo A, et al. (July 1998). "Enoxaparin plus compression stockings compared with compression stockings alone in the prevention of venous thromboembolism after elective neurosurgery". The New England Journal of Medicine. 339 (2): 80–5. doi:10.1056/NEJM199807093390204. PMID 9654538.
Bergqvist D, Agnelli G, Cohen AT, Eldor A, Nilsson PE, Le Moigne-Amrani A, et al. (March 2002). "Duration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancer". The New England Journal of Medicine. 346 (13): 975–80. doi:10.1056/NEJMoa012385. PMID 11919306.
Handoll HH, Farrar MJ, McBirnie J, Tytherleigh-Strong G, Milne AA, Gillespie WJ (2002). "Heparin, low molecular weight heparin and physical methods for preventing deep vein thrombosis and pulmonary embolism following surgery for hip fractures". The Cochrane Database of Systematic Reviews. 2021 (4): CD000305. doi:10.1002/14651858.CD000305. PMC 7043307. PMID 12519540.
Korzewski M, Madden L, Schomer K, Van Leuven K (September 2020). "Heparin Flush Use in Transfemoral Cerebral Angiography Survey". Journal of Radiology Nursing. 39 (3): 199–206. doi:10.1016/j.jradnu.2020.06.001. S2CID 225587226.
Wiersema AM, Watts C, Durran AC, Reijnen MM, van Delden OM, Moll FL, et al. (2016). "The Use of Heparin during Endovascular Peripheral Arterial Interventions: A Synopsis". Scientifica. 2016: 1456298. doi:10.1155/2016/1456298. PMC 4852120. PMID 27190678.
Cronin RE, Reilly RF (2010). "Unfractionated heparin for hemodialysis: still the best option". Seminars in Dialysis. 23 (5): 510–5. doi:10.1111/j.1525-139X.2010.00770.x. PMC 3229102. PMID 21039876.
Ahmed I, Majeed A, Powell R (September 2007). "Heparin induced thrombocytopenia: diagnosis and management update". Postgraduate Medical Journal. 83 (983): 575–582. doi:10.1136/pgmj.2007.059188. PMC 2600013. PMID 17823223.
Nand S, Wong W, Yuen B, Yetter A, Schmulbach E, Gross Fisher S (September 1997). "Heparin-induced thrombocytopenia with thrombosis: incidence, analysis of risk factors, and clinical outcomes in 108 consecutive patients treated at a single institution". American Journal of Hematology. 56 (1): 12–16. doi:10.1002/(sici)1096-8652(199709)56:1<12::aid-ajh3>3.0.co;2-5. PMID 9298861. S2CID 22963756.
Nader HB, Chavante SF, dos-Santos EA, Oliveira TW, de-Paiva JF, Jerônimo SM, et al. (May 1999). "Heparan sulfates and heparins: similar compounds performing the same functions in vertebrates and invertebrates?". Brazilian Journal of Medical and Biological Research = Revista Brasileira de Pesquisas Medicas e Biologicas. 32 (5): 529–38. doi:10.1590/S0100-879X1999000500005. PMID 10412563.
Warda M, Mao W, Toida T, Linhardt RJ (January 2003). "Turkey intestine as a commercial source of heparin? Comparative structural studies of intestinal avian and mammalian glycosaminoglycans". Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 134 (1): 189–97. doi:10.1016/S1096-4959(02)00250-6. PMID 12524047.
Ototani N, Kikuchi M, Yosizawa Z (July 1981). "Comparative studies on the structures of highly active and relatively inactive forms of whale heparin". Journal of Biochemistry. 90 (1): 241–6. doi:10.1093/oxfordjournals.jbchem.a133456. PMID 7287679.
Warda M, Gouda EM, Toida T, Chi L, Linhardt RJ (December 2003). "Isolation and characterization of raw heparin from dromedary intestine: evaluation of a new source of pharmaceutical heparin". Comparative Biochemistry and Physiology. Toxicology & Pharmacology. 136 (4): 357–65. doi:10.1016/j.cca.2003.10.009. PMID 15012907.
Bland CE, Ginsburg H, Silbert JE, Metcalfe DD (August 1982). "Mouse heparin proteoglycan. Synthesis by mast cell-fibroblast monolayers during lymphocyte-dependent mast cell proliferation". The Journal of Biological Chemistry. 257 (15): 8661–6. doi:10.1016/S0021-9258(18)34179-6. PMID 6807978.
Linhardt RJ, Ampofo SA, Fareed J, Hoppensteadt D, Mulliken JB, Folkman J (December 1992). "Isolation and characterization of human heparin". Biochemistry. 31 (49): 12441–5. doi:10.1021/bi00164a020. PMID 1463730.
Hovingh P, Linker A (August 1982). "An unusual heparan sulfate isolated from lobsters (Homarus americanus)". The Journal of Biological Chemistry. 257 (16): 9840–4. doi:10.1016/S0021-9258(18)34147-4. PMID 6213614.
Hovingh P, Linker A (October 1993). "Glycosaminoglycans in Anodonta californiensis, a Freshwater Mussel". The Biological Bulletin. 185 (2): 263–276. doi:10.2307/1542006. JSTOR 1542006. PMID 27768418. S2CID 42108805. Archived from the original on 27 September 2007. Retrieved 22 March 2007.
Pejler G, Danielsson A, Björk I, Lindahl U, Nader HB, Dietrich CP (August 1987). "Structure and antithrombin-binding properties of heparin isolated from the clams Anomalocardia brasiliana and Tivela mactroides". The Journal of Biological Chemistry. 262 (24): 11413–21. doi:10.1016/S0021-9258(18)60822-1. PMID 3624220.
Dietrich CP, Paiva JF, Castro RA, Chavante SF, Jeske W, Fareed J, et al. (August 1999). "Structural features and anticoagulant activities of a novel natural low molecular weight heparin from the shrimp Penaeus brasiliensis". Biochimica et Biophysica Acta (BBA) - General Subjects. 1428 (2–3): 273–83. doi:10.1016/S0304-4165(99)00087-2. PMID 10434045.
Medeiros GF, Mendes A, Castro RA, Baú EC, Nader HB, Dietrich CP (July 2000). "Distribution of sulfated glycosaminoglycans in the animal kingdom: widespread occurrence of heparin-like compounds in invertebrates". Biochimica et Biophysica Acta (BBA) - General Subjects. 1475 (3): 287–94. doi:10.1016/S0304-4165(00)00079-9. PMID 10913828.
Flengsrud R, Larsen ML, Ødegaard OR (December 2010). "Purification, characterization and in vivo studies of salmon heparin". Thrombosis Research. 126 (6): e409-17. doi:10.1016/j.thromres.2010.07.004. PMID 20937523.
Flengsrud R (April 2016). "Disaccharide analysis of chondroitin and heparin from farmed Atlantic salmon". Glycoconjugate Journal. 33 (2): 121–3. doi:10.1007/s10719-016-9652-8. hdl:11250/2388232. PMID 26993287. S2CID 671954.
Zhang F, Zhang Z, Thistle R, McKeen L, Hosoyama S, Toida T, et al. (February 2009). "Structural characterization of glycosaminoglycans from zebrafish in different ages". Glycoconjugate Journal. 26 (2): 211–8. doi:10.1007/s10719-008-9177-x. PMC 2643322. PMID 18777207.
Hetzel GR, Sucker C (October 2005). "The heparins: all a nephrologist should know". Nephrology, Dialysis, Transplantation. 20 (10): 2036–42. doi:10.1093/ndt/gfi004. PMID 16030035.
Chuang YJ, Swanson R, Raja SM, Olson ST (May 2001). "Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin". The Journal of Biological Chemistry. 276 (18): 14961–71. doi:10.1074/jbc.M011550200. PMID 11278930.
Björk I, Lindahl U (October 1982). "Mechanism of the anticoagulant action of heparin". Molecular and Cellular Biochemistry. 48 (3): 161–82. doi:10.1007/BF00421226. PMID 6757715. S2CID 29785682.
Petitou M, Hérault JP, Bernat A, Driguez PA, Duchaussoy P, Lormeau JC, et al. (April 1999). "Synthesis of thrombin-inhibiting heparin mimetics without side effects". Nature. 398 (6726): 417–22. Bibcode:1999Natur.398..417P. doi:10.1038/18877. PMID 10201371. S2CID 4339441.
Eikelboom JW, Hankey GJ (October 2002). "Low molecular weight heparins and heparinoids". The Medical Journal of Australia. 177 (7): 379–83. doi:10.5694/j.1326-5377.2002.tb04807.x. PMID 12358583. S2CID 25553190. Archived from the original on 9 September 2011.
Weitz JI (August 2004). "New anticoagulants for treatment of venous thromboembolism". Circulation. 110 (9 Suppl 1): I19-26. doi:10.1161/01.CIR.0000140901.04538.ae. PMID 15339877.
Hirsh J, Raschke R (September 2004). "Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy". Chest. 126 (3 Suppl): 188S – 203S. doi:10.1378/chest.126.3_suppl.188S. PMID 15383472.
Weitz DS, Weitz JI (February 2010). "Update on heparin: what do we need to know?". Journal of Thrombosis and Thrombolysis. 29 (2): 199–207. doi:10.1007/s11239-009-0411-6. PMID 19882363. S2CID 33367673.
Bentolila A, Vlodavsky I, Haloun C, Domb AJ (2000). "Synthesis and heparin-like biological activity of amino acid-based polymers". Polymers for Advanced Technologies. 11 (8–12): 377–387. doi:10.1002/1099-1581(200008/12)11:8/12<377::AID-PAT985>3.0.CO;2-D.
Gatti G, Casu B, Hamer GK, Perlin AS (1979). "Studies on the Conformation of Heparin by1H and13C NMR Spectroscopy". Macromolecules. 12 (5): 1001–1007. Bibcode:1979MaMol..12.1001G. doi:10.1021/ma60071a044. ISSN 0024-9297.
Ferro DR, Provasoli A, Ragazzi M, Casu B, Torri G, Bossennec V, et al. (January 1990). "Conformer populations of L-iduronic acid residues in glycosaminoglycan sequences". Carbohydrate Research. 195 (2): 157–67. doi:10.1016/0008-6215(90)84164-P. PMID 2331699.
Mulloy B, Forster MJ, Jones C, Davies DB (August 1993). "N.m.r. and molecular-modelling studies of the solution conformation of heparin". The Biochemical Journal. 293 (Pt 3): 849–58. doi:10.1042/bj2930849. PMC 1134446. PMID 8352752.
Shaya D, Tocilj A, Li Y, Myette J, Venkataraman G, Sasisekharan R, et al. (June 2006). "Crystal structure of heparinase II from Pedobacter heparinus and its complex with a disaccharide product". The Journal of Biological Chemistry. 281 (22): 15525–35. doi:10.1074/jbc.M512055200. PMID 16565082.
Galliher PM, Cooney CL, Langer R, Linhardt RJ (February 1981). "Heparinase production by Flavobacterium heparinum". Applied and Environmental Microbiology. 41 (2): 360–5. Bibcode:1981ApEnM..41..360G. doi:10.1128/AEM.41.2.360-365.1981. PMC 243699. PMID 7235692.
Linhardt RJ, Turnbull JE, Wang HM, Loganathan D, Gallagher JT (March 1990). "Examination of the substrate specificity of heparin and heparan sulfate lyases". Biochemistry. 29 (10): 2611–7. doi:10.1021/bi00462a026. PMID 2334685.
Desai UR, Wang HM, Linhardt RJ (August 1993). "Specificity studies on the heparin lyases from Flavobacterium heparinum". Biochemistry. 32 (32): 8140–5. doi:10.1021/bi00083a012. PMID 8347612.
Linker A, Hovingh P (February 1972). "Isolation and characterization of oligosaccharides obtained from heparin by the action of heparinase". Biochemistry. 11 (4): 563–8. doi:10.1021/bi00754a013. PMID 5062409.
Linhardt RJ, Rice KG, Kim YS, Lohse DL, Wang HM, Loganathan D (September 1988). "Mapping and quantification of the major oligosaccharide components of heparin". The Biochemical Journal. 254 (3): 781–7. doi:10.1042/bj2540781. PMC 1135151. PMID 3196292.
Shively JE, Conrad HE (September 1976). "Formation of anhydrosugars in the chemical depolymerization of heparin". Biochemistry. 15 (18): 3932–42. doi:10.1021/bi00663a005. PMID 9127.
Hansen R, Koster A, Kukucka M, Mertzlufft F, Kuppe H (September 2000). "A quick anti-Xa-activity-based whole blood coagulation assay for monitoring unfractionated heparin during cardiopulmonary bypass: a pilot investigation". Anesthesia and Analgesia. 91 (3): 533–8. doi:10.1213/00000539-200009000-00006. PMID 10960371. S2CID 44678237.
Yokota M, Tatsumi N, Nathalang O, Yamada T, Tsuda I (1999). "Effects of heparin on polymerase chain reaction for blood white cells". Journal of Clinical Laboratory Analysis. 13 (3): 133–40. doi:10.1002/(SICI)1098-2825(1999)13:3<133::AID-JCLA8>3.0.CO;2-0. PMC 6807949. PMID 10323479.
Xiong S, Zhang L, He QY (2008). "Fractionation of proteins by heparin chromatography". 2D PAGE: Sample Preparation and Fractionation. Methods in Molecular Biology. Vol. 424. pp. 213–21. doi:10.1007/978-1-60327-064-9_18. ISBN 978-1-58829-722-8. PMID 18369865.
Guibinga GH, Miyanohara A, Esko JD, Friedmann T (May 2002). "Cell surface heparan sulfate is a receptor for attachment of envelope protein-free retrovirus-like particles and VSV-G pseudotyped MLV-derived retrovirus vectors to target cells". Molecular Therapy. 5 (5 Pt 1): 538–46. doi:10.1006/mthe.2002.0578. PMID 11991744.
Segura MM, Kamen A, Garnier A (2008). "Purification of retrovirus particles using heparin affinity chromatography". Gene Therapy Protocols. Methods in Molecular Biology. Vol. 434. pp. 1–11. doi:10.1007/978-1-60327-248-3_1. ISBN 978-1-60327-247-6. PMID 18470635.
Segura MM, Kamen A, Trudel P, Garnier A (May 2005). "A novel purification strategy for retrovirus gene therapy vectors using heparin affinity chromatography". Biotechnology and Bioengineering. 90 (4): 391–404. doi:10.1002/bit.20301. PMID 15812800.
Beni S, Limtiaco JF, Larive CK (January 2011). "Analysis and characterization of heparin impurities". Analytical and Bioanalytical Chemistry. 399 (2): 527–39. doi:10.1007/s00216-010-4121-x. PMC 3015169. PMID 20814668.
Xu Y, Masuko S, Takieddin M, Xu H, Liu R, Jing J, et al. (October 2011). "Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins". Science. 334 (6055): 498–501. Bibcode:2011Sci...334..498X. doi:10.1126/science.1207478. PMC 3425363. PMID 22034431.
Lever R, Page CP (February 2002). "Novel drug development opportunities for heparin". Nature Reviews. Drug Discovery. 1 (2): 140–8. doi:10.1038/nrd724. PMID 12120095. S2CID 7334825.
Coombe DR, Kett WC (February 2005). "Heparan sulfate-protein interactions: therapeutic potential through structure-function insights". Cellular and Molecular Life Sciences. 62 (4): 410–24. doi:10.1007/s00018-004-4293-7. PMID 15719168. S2CID 6380429.
Baba M, Pauwels R, Balzarini J, Arnout J, Desmyter J, De Clercq E (August 1988). "Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro". Proceedings of the National Academy of Sciences of the United States of America. 85 (16): 6132–6. Bibcode:1988PNAS...85.6132B. doi:10.1073/pnas.85.16.6132. PMC 281919. PMID 2457906.

drugdiscoveryonline.com

Darby N (18 September 2018). "The Past And Future Of Managing Raw Material And Process Risks In Biomanufacturing". Drug Discovery Online. VertMarkets. A Supply Chain Under Scrutiny. Archived from the original on 1 November 2018. Retrieved 1 November 2018.

drugs.com

"Heparin Sodium". The American Society of Health-System Pharmacists. Archived from the original on 27 January 2016. Retrieved 1 January 2016.
"Heparin Pregnancy and Breastfeeding Warnings". drugs.com. Archived from the original on 27 January 2016. Retrieved 15 January 2016.
"Protamine Sulfate". The American Society of Health-System Pharmacists. Archived from the original on 6 November 2016. Retrieved 8 December 2016.

fda.gov

"AM2 PAT, Inc. Issues Nationwide Recall of Pre-Filled Heparin Lock Flush Solution USP (5 mL in 12 mL Syringes)" (Press release). US FDA. 20 December 2007. Archived from the original on 23 December 2007.
"Information on Heparin" (Press release). US FDA. Archived from the original on 15 April 2012.
Zawisza J (29 March 2008). "FDA Media Briefing on Heparin" (PDF). U.S. Food and Drug Administration. Archived (PDF) from the original on 6 March 2010. Retrieved 23 April 2008.

foxnews.com

Kusmer K (20 September 2006). "3rd Ind. preemie infant dies of overdose". Fox News. Associated Press. Archived from the original on 18 October 2007. Retrieved 8 January 2007.

gelifesciences.com

"HiTrap Heparin HP". GE Healthcare Life Sciences. Archived from the original on 1 August 2017.

go.com

abcnews.go.com

Vonfremd M, Ibanga I (11 July 2008). "Officials Investigate Infants' Heparin OD at Texas Hospital". ABC News. Archived from the original on 11 July 2008. Retrieved 24 July 2008.

handle.net

hdl.handle.net

World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
Flengsrud R (April 2016). "Disaccharide analysis of chondroitin and heparin from farmed Atlantic salmon". Glycoconjugate Journal. 33 (2): 121–3. doi:10.1007/s10719-016-9652-8. hdl:11250/2388232. PMID 26993287. S2CID 671954.

harvard.edu

ui.adsabs.harvard.edu

Petitou M, Hérault JP, Bernat A, Driguez PA, Duchaussoy P, Lormeau JC, et al. (April 1999). "Synthesis of thrombin-inhibiting heparin mimetics without side effects". Nature. 398 (6726): 417–22. Bibcode:1999Natur.398..417P. doi:10.1038/18877. PMID 10201371. S2CID 4339441.
Gatti G, Casu B, Hamer GK, Perlin AS (1979). "Studies on the Conformation of Heparin by1H and13C NMR Spectroscopy". Macromolecules. 12 (5): 1001–1007. Bibcode:1979MaMol..12.1001G. doi:10.1021/ma60071a044. ISSN 0024-9297.
Galliher PM, Cooney CL, Langer R, Linhardt RJ (February 1981). "Heparinase production by Flavobacterium heparinum". Applied and Environmental Microbiology. 41 (2): 360–5. Bibcode:1981ApEnM..41..360G. doi:10.1128/AEM.41.2.360-365.1981. PMC 243699. PMID 7235692.
Xu Y, Masuko S, Takieddin M, Xu H, Liu R, Jing J, et al. (October 2011). "Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins". Science. 334 (6055): 498–501. Bibcode:2011Sci...334..498X. doi:10.1126/science.1207478. PMC 3425363. PMID 22034431.
Baba M, Pauwels R, Balzarini J, Arnout J, Desmyter J, De Clercq E (August 1988). "Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro". Proceedings of the National Academy of Sciences of the United States of America. 85 (16): 6132–6. Bibcode:1988PNAS...85.6132B. doi:10.1073/pnas.85.16.6132. PMC 281919. PMID 2457906.

healthheritageresearch.com

Rutty CJ. "Miracle Blood Lubricant: Connaught and the Story of Heparin, 1928–1937". Health Heritage Research Services. Archived from the original on 23 August 2007. Retrieved 21 May 2007.

hekint.org

"The discovery of heparin - Hektoen International". hekint.org. 21 March 2024. Retrieved 30 March 2024.

jstor.org

Hovingh P, Linker A (October 1993). "Glycosaminoglycans in Anodonta californiensis, a Freshwater Mussel". The Biological Bulletin. 185 (2): 263–276. doi:10.2307/1542006. JSTOR 1542006. PMID 27768418. S2CID 42108805. Archived from the original on 27 September 2007. Retrieved 22 March 2007.

ketv.com

"Nebraska Med. Center Investigates Staff After Girl's Death". KETV Omaha. 31 March 2010. Archived from the original on 20 March 2012.

latimes.com

Ornstein C (5 December 2007). "Dennis Quaid files suit over drug mishap". Los Angeles Times. Archived from the original on 4 July 2008.

lexi.com

online.lexi.com

"Heparin". 10 February 2012. Archived from the original on 14 February 2012.

medicines.org.uk

"Heparin (Mucous) Injection BP – Summary of Product Characteristics". Electronic Medicines Compendium. September 2016. Archived from the original on 20 December 2016. Retrieved 15 December 2016.

mja.com.au

Eikelboom JW, Hankey GJ (October 2002). "Low molecular weight heparins and heparinoids". The Medical Journal of Australia. 177 (7): 379–83. doi:10.5694/j.1326-5377.2002.tb04807.x. PMID 12358583. S2CID 25553190. Archived from the original on 9 September 2011.

mlo-online.com

Higgins C (October 2007). "The use of heparin in preparing samples for blood-gas analysis" (PDF). Medical Laboratory Observer. 39 (10): 16–8, 20, quiz 22–3. PMID 18018679. Archived from the original (PDF) on 10 September 2016. Retrieved 18 April 2016.

ncl.ac.uk

cancerweb.ncl.ac.uk

"Online Medical Dictionary". Centre for Cancer Education. 2000. Archived from the original on 13 August 2007. Retrieved 11 July 2008.

netreturns.biz

christusspohn.netreturns.biz

Statement by Dr. Richard Davis, Chief Medical Officer, CHRISTUS Spohn Health System^{[permanent dead link‍]}, 10 July 2008

nih.gov

pubmed.ncbi.nlm.nih.gov

Alquwaizani M, Buckley L, Adams C, Fanikos J (June 2013). "Anticoagulants: A Review of the Pharmacology, Dosing, and Complications". Current Emergency and Hospital Medicine Reports. 1 (2): 83–97. doi:10.1007/s40138-013-0014-6. PMC 3654192. PMID 23687625.
Greinacher A, Thiele T, Warkentin TE, Weisser K, Kyrle PA, Eichinger S (June 2021). "Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination". The New England Journal of Medicine. 384 (22): 2092–2101. doi:10.1056/NEJMoa2104840. PMC 8095372. PMID 33835769.
McLEAN J (January 1959). "The discovery of heparin". Circulation. 19 (1): 75–8. doi:10.1161/01.CIR.19.1.75. PMID 13619023.
Mueller RL, Scheidt S (January 1994). "History of drugs for thrombotic disease. Discovery, development, and directions for the future". Circulation. 89 (1): 432–49. doi:10.1161/01.cir.89.1.432. PMID 8281678.
Jorpes E (August 1935). "The chemistry of heparin". The Biochemical Journal. 29 (8): 1817–30. doi:10.1042/bj0291817. PMC 1266692. PMID 16745848.
Prinz B (April 2022). "How blood met plastics, plant and animal extracts: Material encounters between medicine and industry in the twentieth century". Studies in History and Philosophy of Science. 92: 45–55. doi:10.1016/j.shpsa.2022.01.007. PMID 35131685. S2CID 246575794.
Warnock LB, Huang D (2022). "Heparin". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 30855835. Retrieved 31 October 2022.
Agnelli G, Piovella F, Buoncristiani P, Severi P, Pini M, D'Angelo A, et al. (July 1998). "Enoxaparin plus compression stockings compared with compression stockings alone in the prevention of venous thromboembolism after elective neurosurgery". The New England Journal of Medicine. 339 (2): 80–5. doi:10.1056/NEJM199807093390204. PMID 9654538.
Bergqvist D, Agnelli G, Cohen AT, Eldor A, Nilsson PE, Le Moigne-Amrani A, et al. (March 2002). "Duration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancer". The New England Journal of Medicine. 346 (13): 975–80. doi:10.1056/NEJMoa012385. PMID 11919306.
Handoll HH, Farrar MJ, McBirnie J, Tytherleigh-Strong G, Milne AA, Gillespie WJ (2002). "Heparin, low molecular weight heparin and physical methods for preventing deep vein thrombosis and pulmonary embolism following surgery for hip fractures". The Cochrane Database of Systematic Reviews. 2021 (4): CD000305. doi:10.1002/14651858.CD000305. PMC 7043307. PMID 12519540.
Wiersema AM, Watts C, Durran AC, Reijnen MM, van Delden OM, Moll FL, et al. (2016). "The Use of Heparin during Endovascular Peripheral Arterial Interventions: A Synopsis". Scientifica. 2016: 1456298. doi:10.1155/2016/1456298. PMC 4852120. PMID 27190678.
Cronin RE, Reilly RF (2010). "Unfractionated heparin for hemodialysis: still the best option". Seminars in Dialysis. 23 (5): 510–5. doi:10.1111/j.1525-139X.2010.00770.x. PMC 3229102. PMID 21039876.
Ahmed I, Majeed A, Powell R (September 2007). "Heparin induced thrombocytopenia: diagnosis and management update". Postgraduate Medical Journal. 83 (983): 575–582. doi:10.1136/pgmj.2007.059188. PMC 2600013. PMID 17823223.
Nand S, Wong W, Yuen B, Yetter A, Schmulbach E, Gross Fisher S (September 1997). "Heparin-induced thrombocytopenia with thrombosis: incidence, analysis of risk factors, and clinical outcomes in 108 consecutive patients treated at a single institution". American Journal of Hematology. 56 (1): 12–16. doi:10.1002/(sici)1096-8652(199709)56:1<12::aid-ajh3>3.0.co;2-5. PMID 9298861. S2CID 22963756.
Nader HB, Chavante SF, dos-Santos EA, Oliveira TW, de-Paiva JF, Jerônimo SM, et al. (May 1999). "Heparan sulfates and heparins: similar compounds performing the same functions in vertebrates and invertebrates?". Brazilian Journal of Medical and Biological Research = Revista Brasileira de Pesquisas Medicas e Biologicas. 32 (5): 529–38. doi:10.1590/S0100-879X1999000500005. PMID 10412563.
Warda M, Mao W, Toida T, Linhardt RJ (January 2003). "Turkey intestine as a commercial source of heparin? Comparative structural studies of intestinal avian and mammalian glycosaminoglycans". Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 134 (1): 189–97. doi:10.1016/S1096-4959(02)00250-6. PMID 12524047.
Ototani N, Kikuchi M, Yosizawa Z (July 1981). "Comparative studies on the structures of highly active and relatively inactive forms of whale heparin". Journal of Biochemistry. 90 (1): 241–6. doi:10.1093/oxfordjournals.jbchem.a133456. PMID 7287679.
Warda M, Gouda EM, Toida T, Chi L, Linhardt RJ (December 2003). "Isolation and characterization of raw heparin from dromedary intestine: evaluation of a new source of pharmaceutical heparin". Comparative Biochemistry and Physiology. Toxicology & Pharmacology. 136 (4): 357–65. doi:10.1016/j.cca.2003.10.009. PMID 15012907.
Bland CE, Ginsburg H, Silbert JE, Metcalfe DD (August 1982). "Mouse heparin proteoglycan. Synthesis by mast cell-fibroblast monolayers during lymphocyte-dependent mast cell proliferation". The Journal of Biological Chemistry. 257 (15): 8661–6. doi:10.1016/S0021-9258(18)34179-6. PMID 6807978.
Linhardt RJ, Ampofo SA, Fareed J, Hoppensteadt D, Mulliken JB, Folkman J (December 1992). "Isolation and characterization of human heparin". Biochemistry. 31 (49): 12441–5. doi:10.1021/bi00164a020. PMID 1463730.
Hovingh P, Linker A (August 1982). "An unusual heparan sulfate isolated from lobsters (Homarus americanus)". The Journal of Biological Chemistry. 257 (16): 9840–4. doi:10.1016/S0021-9258(18)34147-4. PMID 6213614.
Hovingh P, Linker A (October 1993). "Glycosaminoglycans in Anodonta californiensis, a Freshwater Mussel". The Biological Bulletin. 185 (2): 263–276. doi:10.2307/1542006. JSTOR 1542006. PMID 27768418. S2CID 42108805. Archived from the original on 27 September 2007. Retrieved 22 March 2007.
Pejler G, Danielsson A, Björk I, Lindahl U, Nader HB, Dietrich CP (August 1987). "Structure and antithrombin-binding properties of heparin isolated from the clams Anomalocardia brasiliana and Tivela mactroides". The Journal of Biological Chemistry. 262 (24): 11413–21. doi:10.1016/S0021-9258(18)60822-1. PMID 3624220.
Dietrich CP, Paiva JF, Castro RA, Chavante SF, Jeske W, Fareed J, et al. (August 1999). "Structural features and anticoagulant activities of a novel natural low molecular weight heparin from the shrimp Penaeus brasiliensis". Biochimica et Biophysica Acta (BBA) - General Subjects. 1428 (2–3): 273–83. doi:10.1016/S0304-4165(99)00087-2. PMID 10434045.
Medeiros GF, Mendes A, Castro RA, Baú EC, Nader HB, Dietrich CP (July 2000). "Distribution of sulfated glycosaminoglycans in the animal kingdom: widespread occurrence of heparin-like compounds in invertebrates". Biochimica et Biophysica Acta (BBA) - General Subjects. 1475 (3): 287–94. doi:10.1016/S0304-4165(00)00079-9. PMID 10913828.
Flengsrud R, Larsen ML, Ødegaard OR (December 2010). "Purification, characterization and in vivo studies of salmon heparin". Thrombosis Research. 126 (6): e409-17. doi:10.1016/j.thromres.2010.07.004. PMID 20937523.
Flengsrud R (April 2016). "Disaccharide analysis of chondroitin and heparin from farmed Atlantic salmon". Glycoconjugate Journal. 33 (2): 121–3. doi:10.1007/s10719-016-9652-8. hdl:11250/2388232. PMID 26993287. S2CID 671954.
Zhang F, Zhang Z, Thistle R, McKeen L, Hosoyama S, Toida T, et al. (February 2009). "Structural characterization of glycosaminoglycans from zebrafish in different ages". Glycoconjugate Journal. 26 (2): 211–8. doi:10.1007/s10719-008-9177-x. PMC 2643322. PMID 18777207.
Hetzel GR, Sucker C (October 2005). "The heparins: all a nephrologist should know". Nephrology, Dialysis, Transplantation. 20 (10): 2036–42. doi:10.1093/ndt/gfi004. PMID 16030035.
Chuang YJ, Swanson R, Raja SM, Olson ST (May 2001). "Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin". The Journal of Biological Chemistry. 276 (18): 14961–71. doi:10.1074/jbc.M011550200. PMID 11278930.
Björk I, Lindahl U (October 1982). "Mechanism of the anticoagulant action of heparin". Molecular and Cellular Biochemistry. 48 (3): 161–82. doi:10.1007/BF00421226. PMID 6757715. S2CID 29785682.
Petitou M, Hérault JP, Bernat A, Driguez PA, Duchaussoy P, Lormeau JC, et al. (April 1999). "Synthesis of thrombin-inhibiting heparin mimetics without side effects". Nature. 398 (6726): 417–22. Bibcode:1999Natur.398..417P. doi:10.1038/18877. PMID 10201371. S2CID 4339441.
Eikelboom JW, Hankey GJ (October 2002). "Low molecular weight heparins and heparinoids". The Medical Journal of Australia. 177 (7): 379–83. doi:10.5694/j.1326-5377.2002.tb04807.x. PMID 12358583. S2CID 25553190. Archived from the original on 9 September 2011.
Weitz JI (August 2004). "New anticoagulants for treatment of venous thromboembolism". Circulation. 110 (9 Suppl 1): I19-26. doi:10.1161/01.CIR.0000140901.04538.ae. PMID 15339877.
Hirsh J, Raschke R (September 2004). "Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy". Chest. 126 (3 Suppl): 188S – 203S. doi:10.1378/chest.126.3_suppl.188S. PMID 15383472.
Weitz DS, Weitz JI (February 2010). "Update on heparin: what do we need to know?". Journal of Thrombosis and Thrombolysis. 29 (2): 199–207. doi:10.1007/s11239-009-0411-6. PMID 19882363. S2CID 33367673.
Ferro DR, Provasoli A, Ragazzi M, Casu B, Torri G, Bossennec V, et al. (January 1990). "Conformer populations of L-iduronic acid residues in glycosaminoglycan sequences". Carbohydrate Research. 195 (2): 157–67. doi:10.1016/0008-6215(90)84164-P. PMID 2331699.
Mulloy B, Forster MJ, Jones C, Davies DB (August 1993). "N.m.r. and molecular-modelling studies of the solution conformation of heparin". The Biochemical Journal. 293 (Pt 3): 849–58. doi:10.1042/bj2930849. PMC 1134446. PMID 8352752.
Shaya D, Tocilj A, Li Y, Myette J, Venkataraman G, Sasisekharan R, et al. (June 2006). "Crystal structure of heparinase II from Pedobacter heparinus and its complex with a disaccharide product". The Journal of Biological Chemistry. 281 (22): 15525–35. doi:10.1074/jbc.M512055200. PMID 16565082.
Galliher PM, Cooney CL, Langer R, Linhardt RJ (February 1981). "Heparinase production by Flavobacterium heparinum". Applied and Environmental Microbiology. 41 (2): 360–5. Bibcode:1981ApEnM..41..360G. doi:10.1128/AEM.41.2.360-365.1981. PMC 243699. PMID 7235692.
Linhardt RJ, Turnbull JE, Wang HM, Loganathan D, Gallagher JT (March 1990). "Examination of the substrate specificity of heparin and heparan sulfate lyases". Biochemistry. 29 (10): 2611–7. doi:10.1021/bi00462a026. PMID 2334685.
Desai UR, Wang HM, Linhardt RJ (August 1993). "Specificity studies on the heparin lyases from Flavobacterium heparinum". Biochemistry. 32 (32): 8140–5. doi:10.1021/bi00083a012. PMID 8347612.
Linker A, Hovingh P (February 1972). "Isolation and characterization of oligosaccharides obtained from heparin by the action of heparinase". Biochemistry. 11 (4): 563–8. doi:10.1021/bi00754a013. PMID 5062409.
Linhardt RJ, Rice KG, Kim YS, Lohse DL, Wang HM, Loganathan D (September 1988). "Mapping and quantification of the major oligosaccharide components of heparin". The Biochemical Journal. 254 (3): 781–7. doi:10.1042/bj2540781. PMC 1135151. PMID 3196292.
Shively JE, Conrad HE (September 1976). "Formation of anhydrosugars in the chemical depolymerization of heparin". Biochemistry. 15 (18): 3932–42. doi:10.1021/bi00663a005. PMID 9127.
Hansen R, Koster A, Kukucka M, Mertzlufft F, Kuppe H (September 2000). "A quick anti-Xa-activity-based whole blood coagulation assay for monitoring unfractionated heparin during cardiopulmonary bypass: a pilot investigation". Anesthesia and Analgesia. 91 (3): 533–8. doi:10.1213/00000539-200009000-00006. PMID 10960371. S2CID 44678237.
Higgins C (October 2007). "The use of heparin in preparing samples for blood-gas analysis" (PDF). Medical Laboratory Observer. 39 (10): 16–8, 20, quiz 22–3. PMID 18018679. Archived from the original (PDF) on 10 September 2016. Retrieved 18 April 2016.
Yokota M, Tatsumi N, Nathalang O, Yamada T, Tsuda I (1999). "Effects of heparin on polymerase chain reaction for blood white cells". Journal of Clinical Laboratory Analysis. 13 (3): 133–40. doi:10.1002/(SICI)1098-2825(1999)13:3<133::AID-JCLA8>3.0.CO;2-0. PMC 6807949. PMID 10323479.
Xiong S, Zhang L, He QY (2008). "Fractionation of proteins by heparin chromatography". 2D PAGE: Sample Preparation and Fractionation. Methods in Molecular Biology. Vol. 424. pp. 213–21. doi:10.1007/978-1-60327-064-9_18. ISBN 978-1-58829-722-8. PMID 18369865.
Guibinga GH, Miyanohara A, Esko JD, Friedmann T (May 2002). "Cell surface heparan sulfate is a receptor for attachment of envelope protein-free retrovirus-like particles and VSV-G pseudotyped MLV-derived retrovirus vectors to target cells". Molecular Therapy. 5 (5 Pt 1): 538–46. doi:10.1006/mthe.2002.0578. PMID 11991744.
Segura MM, Kamen A, Garnier A (2008). "Purification of retrovirus particles using heparin affinity chromatography". Gene Therapy Protocols. Methods in Molecular Biology. Vol. 434. pp. 1–11. doi:10.1007/978-1-60327-248-3_1. ISBN 978-1-60327-247-6. PMID 18470635.
Segura MM, Kamen A, Trudel P, Garnier A (May 2005). "A novel purification strategy for retrovirus gene therapy vectors using heparin affinity chromatography". Biotechnology and Bioengineering. 90 (4): 391–404. doi:10.1002/bit.20301. PMID 15812800.
Beni S, Limtiaco JF, Larive CK (January 2011). "Analysis and characterization of heparin impurities". Analytical and Bioanalytical Chemistry. 399 (2): 527–39. doi:10.1007/s00216-010-4121-x. PMC 3015169. PMID 20814668.
Linhardt RJ, Gunay NS (1999). "Production and chemical processing of low molecular weight heparins". Seminars in Thrombosis and Hemostasis. 25 (Suppl 3): 5–16. PMID 10549711.
Xu Y, Masuko S, Takieddin M, Xu H, Liu R, Jing J, et al. (October 2011). "Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins". Science. 334 (6055): 498–501. Bibcode:2011Sci...334..498X. doi:10.1126/science.1207478. PMC 3425363. PMID 22034431.
Lever R, Page CP (February 2002). "Novel drug development opportunities for heparin". Nature Reviews. Drug Discovery. 1 (2): 140–8. doi:10.1038/nrd724. PMID 12120095. S2CID 7334825.
Coombe DR, Kett WC (February 2005). "Heparan sulfate-protein interactions: therapeutic potential through structure-function insights". Cellular and Molecular Life Sciences. 62 (4): 410–24. doi:10.1007/s00018-004-4293-7. PMID 15719168. S2CID 6380429.
Baba M, Pauwels R, Balzarini J, Arnout J, Desmyter J, De Clercq E (August 1988). "Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro". Proceedings of the National Academy of Sciences of the United States of America. 85 (16): 6132–6. Bibcode:1988PNAS...85.6132B. doi:10.1073/pnas.85.16.6132. PMC 281919. PMID 2457906.

ncbi.nlm.nih.gov

Alquwaizani M, Buckley L, Adams C, Fanikos J (June 2013). "Anticoagulants: A Review of the Pharmacology, Dosing, and Complications". Current Emergency and Hospital Medicine Reports. 1 (2): 83–97. doi:10.1007/s40138-013-0014-6. PMC 3654192. PMID 23687625.
Greinacher A, Thiele T, Warkentin TE, Weisser K, Kyrle PA, Eichinger S (June 2021). "Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination". The New England Journal of Medicine. 384 (22): 2092–2101. doi:10.1056/NEJMoa2104840. PMC 8095372. PMID 33835769.
Jorpes E (August 1935). "The chemistry of heparin". The Biochemical Journal. 29 (8): 1817–30. doi:10.1042/bj0291817. PMC 1266692. PMID 16745848.
Warnock LB, Huang D (2022). "Heparin". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 30855835. Retrieved 31 October 2022.
Handoll HH, Farrar MJ, McBirnie J, Tytherleigh-Strong G, Milne AA, Gillespie WJ (2002). "Heparin, low molecular weight heparin and physical methods for preventing deep vein thrombosis and pulmonary embolism following surgery for hip fractures". The Cochrane Database of Systematic Reviews. 2021 (4): CD000305. doi:10.1002/14651858.CD000305. PMC 7043307. PMID 12519540.
Wiersema AM, Watts C, Durran AC, Reijnen MM, van Delden OM, Moll FL, et al. (2016). "The Use of Heparin during Endovascular Peripheral Arterial Interventions: A Synopsis". Scientifica. 2016: 1456298. doi:10.1155/2016/1456298. PMC 4852120. PMID 27190678.
Cronin RE, Reilly RF (2010). "Unfractionated heparin for hemodialysis: still the best option". Seminars in Dialysis. 23 (5): 510–5. doi:10.1111/j.1525-139X.2010.00770.x. PMC 3229102. PMID 21039876.
Ahmed I, Majeed A, Powell R (September 2007). "Heparin induced thrombocytopenia: diagnosis and management update". Postgraduate Medical Journal. 83 (983): 575–582. doi:10.1136/pgmj.2007.059188. PMC 2600013. PMID 17823223.
Zhang F, Zhang Z, Thistle R, McKeen L, Hosoyama S, Toida T, et al. (February 2009). "Structural characterization of glycosaminoglycans from zebrafish in different ages". Glycoconjugate Journal. 26 (2): 211–8. doi:10.1007/s10719-008-9177-x. PMC 2643322. PMID 18777207.
Mulloy B, Forster MJ, Jones C, Davies DB (August 1993). "N.m.r. and molecular-modelling studies of the solution conformation of heparin". The Biochemical Journal. 293 (Pt 3): 849–58. doi:10.1042/bj2930849. PMC 1134446. PMID 8352752.
Galliher PM, Cooney CL, Langer R, Linhardt RJ (February 1981). "Heparinase production by Flavobacterium heparinum". Applied and Environmental Microbiology. 41 (2): 360–5. Bibcode:1981ApEnM..41..360G. doi:10.1128/AEM.41.2.360-365.1981. PMC 243699. PMID 7235692.
Linhardt RJ, Rice KG, Kim YS, Lohse DL, Wang HM, Loganathan D (September 1988). "Mapping and quantification of the major oligosaccharide components of heparin". The Biochemical Journal. 254 (3): 781–7. doi:10.1042/bj2540781. PMC 1135151. PMID 3196292.
Yokota M, Tatsumi N, Nathalang O, Yamada T, Tsuda I (1999). "Effects of heparin on polymerase chain reaction for blood white cells". Journal of Clinical Laboratory Analysis. 13 (3): 133–40. doi:10.1002/(SICI)1098-2825(1999)13:3<133::AID-JCLA8>3.0.CO;2-0. PMC 6807949. PMID 10323479.
Beni S, Limtiaco JF, Larive CK (January 2011). "Analysis and characterization of heparin impurities". Analytical and Bioanalytical Chemistry. 399 (2): 527–39. doi:10.1007/s00216-010-4121-x. PMC 3015169. PMID 20814668.
Xu Y, Masuko S, Takieddin M, Xu H, Liu R, Jing J, et al. (October 2011). "Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins". Science. 334 (6055): 498–501. Bibcode:2011Sci...334..498X. doi:10.1126/science.1207478. PMC 3425363. PMID 22034431.
Baba M, Pauwels R, Balzarini J, Arnout J, Desmyter J, De Clercq E (August 1988). "Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro". Proceedings of the National Academy of Sciences of the United States of America. 85 (16): 6132–6. Bibcode:1988PNAS...85.6132B. doi:10.1073/pnas.85.16.6132. PMC 281919. PMID 2457906.

radio.cz

Velinger J (12 May 2006). "Nurse committed murders to "test" doctors". Radio Praha. Archived from the original on 24 September 2009.

rcsb.org

Mulloy B, Forster MJ. "N.M.R. and molecular-modeling studies of the solution conformation of heparin". Archived from the original on 11 October 2008. Retrieved 17 July 2006.

rsc.org

Bhattacharya A (August 2008). "Flask synthesis promises untainted heparin". Chemistry World. Royal Society of Chemistry. Archived from the original on 21 October 2012. Retrieved 6 February 2011.

semanticscholar.org

api.semanticscholar.org

Pai M, Grill A, Ivers N (26 March 2021). "Vaccine-Induced Prothrombotic Immune Thrombocytopenia (VIPIT) Following AstraZeneca COVID-19 Vaccination" (PDF). The Ontario COVID-19 Science Advisory Table. doi:10.47326/ocsat.2021.02.17.1.0. S2CID 233663558. Archived (PDF) from the original on 30 March 2021. Retrieved 3 April 2021. {{cite journal}}: Cite journal requires |journal= (help)
Prinz B (April 2022). "How blood met plastics, plant and animal extracts: Material encounters between medicine and industry in the twentieth century". Studies in History and Philosophy of Science. 92: 45–55. doi:10.1016/j.shpsa.2022.01.007. PMID 35131685. S2CID 246575794.
Korzewski M, Madden L, Schomer K, Van Leuven K (September 2020). "Heparin Flush Use in Transfemoral Cerebral Angiography Survey". Journal of Radiology Nursing. 39 (3): 199–206. doi:10.1016/j.jradnu.2020.06.001. S2CID 225587226.
Nand S, Wong W, Yuen B, Yetter A, Schmulbach E, Gross Fisher S (September 1997). "Heparin-induced thrombocytopenia with thrombosis: incidence, analysis of risk factors, and clinical outcomes in 108 consecutive patients treated at a single institution". American Journal of Hematology. 56 (1): 12–16. doi:10.1002/(sici)1096-8652(199709)56:1<12::aid-ajh3>3.0.co;2-5. PMID 9298861. S2CID 22963756.
Hovingh P, Linker A (October 1993). "Glycosaminoglycans in Anodonta californiensis, a Freshwater Mussel". The Biological Bulletin. 185 (2): 263–276. doi:10.2307/1542006. JSTOR 1542006. PMID 27768418. S2CID 42108805. Archived from the original on 27 September 2007. Retrieved 22 March 2007.
Flengsrud R (April 2016). "Disaccharide analysis of chondroitin and heparin from farmed Atlantic salmon". Glycoconjugate Journal. 33 (2): 121–3. doi:10.1007/s10719-016-9652-8. hdl:11250/2388232. PMID 26993287. S2CID 671954.
Björk I, Lindahl U (October 1982). "Mechanism of the anticoagulant action of heparin". Molecular and Cellular Biochemistry. 48 (3): 161–82. doi:10.1007/BF00421226. PMID 6757715. S2CID 29785682.
Petitou M, Hérault JP, Bernat A, Driguez PA, Duchaussoy P, Lormeau JC, et al. (April 1999). "Synthesis of thrombin-inhibiting heparin mimetics without side effects". Nature. 398 (6726): 417–22. Bibcode:1999Natur.398..417P. doi:10.1038/18877. PMID 10201371. S2CID 4339441.
Eikelboom JW, Hankey GJ (October 2002). "Low molecular weight heparins and heparinoids". The Medical Journal of Australia. 177 (7): 379–83. doi:10.5694/j.1326-5377.2002.tb04807.x. PMID 12358583. S2CID 25553190. Archived from the original on 9 September 2011.
Weitz DS, Weitz JI (February 2010). "Update on heparin: what do we need to know?". Journal of Thrombosis and Thrombolysis. 29 (2): 199–207. doi:10.1007/s11239-009-0411-6. PMID 19882363. S2CID 33367673.
Hansen R, Koster A, Kukucka M, Mertzlufft F, Kuppe H (September 2000). "A quick anti-Xa-activity-based whole blood coagulation assay for monitoring unfractionated heparin during cardiopulmonary bypass: a pilot investigation". Anesthesia and Analgesia. 91 (3): 533–8. doi:10.1213/00000539-200009000-00006. PMID 10960371. S2CID 44678237.
Lever R, Page CP (February 2002). "Novel drug development opportunities for heparin". Nature Reviews. Drug Discovery. 1 (2): 140–8. doi:10.1038/nrd724. PMID 12120095. S2CID 7334825.
Coombe DR, Kett WC (February 2005). "Heparan sulfate-protein interactions: therapeutic potential through structure-function insights". Cellular and Molecular Life Sciences. 62 (4): 410–24. doi:10.1007/s00018-004-4293-7. PMID 15719168. S2CID 6380429.

sfgate.com

"Quaid Awarded $750,000 Over Hospital Negligence". SFGate.com. 16 December 2008. Archived from the original on 15 April 2009.

sigmaaldrich.com

"Affinity Chromatography". Sigma-Aldrich. Archived from the original on 7 May 2016.
"Performing a Separation of DNA binding proteins with GE Healthcare Products Based on Heparin". Sigma-Aldrich. Archived from the original on 16 April 2019. Retrieved 16 April 2019.

tga.gov.au

"Heparin Interpharma APMDS". Therapeutic Goods Administration (TGA). 7 December 2023. Retrieved 7 March 2024.

usatoday.com

Jablon R (4 December 2007). "Dennis Quaid and wife sue drug maker". USA Today. Archived from the original on 28 June 2010.

vhpharmsci.com

Shalansky, Karen. DANAPAROID (Orgaran) for Heparin-Induced Thrombocytopenia. Archived 28 September 2007 at the Wayback Machine Vancouver Hospital & Health Sciences Centre, February 1998 Drug & Therapeutics Newsletter. Retrieved on 8 January 2007.

web.archive.org

"Heparin". 10 February 2012. Archived from the original on 14 February 2012.
"Heparin Sodium". The American Society of Health-System Pharmacists. Archived from the original on 27 January 2016. Retrieved 1 January 2016.
"Heparin (Mucous) Injection BP – Summary of Product Characteristics". Electronic Medicines Compendium. September 2016. Archived from the original on 20 December 2016. Retrieved 15 December 2016.
McClatchey KD (2002). Clinical Laboratory Medicine. Lippincott Williams & Wilkins. p. 662. ISBN 978-0-683-30751-1. Archived from the original on 10 September 2017.
"AstraZeneca COVID-19-Vakzine Umgang mit dem Risiko von Gerinnungskomplikationen" (PDF). Archived (PDF) from the original on 13 January 2024. Retrieved 3 April 2021.
Pai M, Grill A, Ivers N (26 March 2021). "Vaccine-Induced Prothrombotic Immune Thrombocytopenia (VIPIT) Following AstraZeneca COVID-19 Vaccination" (PDF). The Ontario COVID-19 Science Advisory Table. doi:10.47326/ocsat.2021.02.17.1.0. S2CID 233663558. Archived (PDF) from the original on 30 March 2021. Retrieved 3 April 2021. {{cite journal}}: Cite journal requires |journal= (help)
"Heparin Pregnancy and Breastfeeding Warnings". drugs.com. Archived from the original on 27 January 2016. Retrieved 15 January 2016.
Li JL, Corey EJ (2013). Drug Discovery: Practices, Processes, and Perspectives. John Wiley & Sons. p. 189. ISBN 978-1-118-35446-9. Archived from the original on 10 September 2017.
Rietschel RL, Fowler JF, Fisher AA (2008). Fisher's Contact Dermatitis. PMPH-USA. p. 142. ISBN 978-1-55009-378-0. Archived from the original on 10 September 2017.
"Heparin used as an anticoagulant". AnimalResearch.info. Archived from the original on 23 October 2013.
Rutty CJ. "Miracle Blood Lubricant: Connaught and the Story of Heparin, 1928–1937". Health Heritage Research Services. Archived from the original on 23 August 2007. Retrieved 21 May 2007.
Kusmer K (20 September 2006). "3rd Ind. preemie infant dies of overdose". Fox News. Associated Press. Archived from the original on 18 October 2007. Retrieved 8 January 2007.
"Protamine Sulfate". The American Society of Health-System Pharmacists. Archived from the original on 6 November 2016. Retrieved 8 December 2016.
Hovingh P, Linker A (October 1993). "Glycosaminoglycans in Anodonta californiensis, a Freshwater Mussel". The Biological Bulletin. 185 (2): 263–276. doi:10.2307/1542006. JSTOR 1542006. PMID 27768418. S2CID 42108805. Archived from the original on 27 September 2007. Retrieved 22 March 2007.
Shalansky, Karen. DANAPAROID (Orgaran) for Heparin-Induced Thrombocytopenia. Archived 28 September 2007 at the Wayback Machine Vancouver Hospital & Health Sciences Centre, February 1998 Drug & Therapeutics Newsletter. Retrieved on 8 January 2007.
Eikelboom JW, Hankey GJ (October 2002). "Low molecular weight heparins and heparinoids". The Medical Journal of Australia. 177 (7): 379–83. doi:10.5694/j.1326-5377.2002.tb04807.x. PMID 12358583. S2CID 25553190. Archived from the original on 9 September 2011.
Francis CW, Kaplan KL (2006). "Chapter 21. Principles of Antithrombotic Therapy". In Lichtman MA, Beutler E, Kipps TJ, et al. (eds.). Williams Hematology (7th ed.). McGraw-Hill Companies,Incorporated. ISBN 978-0-07-143591-8. Archived from the original on 7 July 2011.
Mulloy B, Forster MJ. "N.M.R. and molecular-modeling studies of the solution conformation of heparin". Archived from the original on 11 October 2008. Retrieved 17 July 2006.
Higgins C (October 2007). "The use of heparin in preparing samples for blood-gas analysis" (PDF). Medical Laboratory Observer. 39 (10): 16–8, 20, quiz 22–3. PMID 18018679. Archived from the original (PDF) on 10 September 2016. Retrieved 18 April 2016.
"Affinity Chromatography". Sigma-Aldrich. Archived from the original on 7 May 2016.
"HiTrap Heparin HP". GE Healthcare Life Sciences. Archived from the original on 1 August 2017.
"Performing a Separation of DNA binding proteins with GE Healthcare Products Based on Heparin". Sigma-Aldrich. Archived from the original on 16 April 2019. Retrieved 16 April 2019.
Rollason B (21 December 2021). "Melbourne researchers trial use of common blood-thinning drug heparin to combat COVID-19". ABC News. Archived from the original on 22 December 2021. Retrieved 22 December 2021.
Margo J (19 January 2022). "A 70-year-old drug may be the answer to treating COVID-19". The Australian Financial Review. Archived from the original on 22 January 2022. Retrieved 22 January 2022.
"AM2 PAT, Inc. Issues Nationwide Recall of Pre-Filled Heparin Lock Flush Solution USP (5 mL in 12 mL Syringes)" (Press release). US FDA. 20 December 2007. Archived from the original on 23 December 2007.
CBS News. "Blood-thinning drug under suspicion". Archived from the original on 23 October 2012.
"Information on Heparin" (Press release). US FDA. Archived from the original on 15 April 2012.
Darby N (18 September 2018). "The Past And Future Of Managing Raw Material And Process Risks In Biomanufacturing". Drug Discovery Online. VertMarkets. A Supply Chain Under Scrutiny. Archived from the original on 1 November 2018. Retrieved 1 November 2018.
Zawisza J (29 March 2008). "FDA Media Briefing on Heparin" (PDF). U.S. Food and Drug Administration. Archived (PDF) from the original on 6 March 2010. Retrieved 23 April 2008.
Velinger J (12 May 2006). "Nurse committed murders to "test" doctors". Radio Praha. Archived from the original on 24 September 2009.
Ornstein C, Gorman A (21 November 2007). "Report: Dennis Quaid's twins get accidental overdose". Los Angeles Times. Archived from the original on 7 March 2008.
Jablon R (4 December 2007). "Dennis Quaid and wife sue drug maker". USA Today. Archived from the original on 28 June 2010.
Ornstein C (5 December 2007). "Dennis Quaid files suit over drug mishap". Los Angeles Times. Archived from the original on 4 July 2008.
"Quaid Awarded $750,000 Over Hospital Negligence". SFGate.com. 16 December 2008. Archived from the original on 15 April 2009.
Sanz A. "Coroner's office investigates infant deaths". WTHR NBC News. Archived from the original on 29 June 2011.
"At a Glance Heparin Overdose at Hospital". Dallas Morning News. 11 July 2008. Archived from the original on 25 October 2008.
Vonfremd M, Ibanga I (11 July 2008). "Officials Investigate Infants' Heparin OD at Texas Hospital". ABC News. Archived from the original on 11 July 2008. Retrieved 24 July 2008.
"Nebraska Med. Center Investigates Staff After Girl's Death". KETV Omaha. 31 March 2010. Archived from the original on 20 March 2012.
Bhattacharya A (August 2008). "Flask synthesis promises untainted heparin". Chemistry World. Royal Society of Chemistry. Archived from the original on 21 October 2012. Retrieved 6 February 2011.

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Gatti G, Casu B, Hamer GK, Perlin AS (1979). "Studies on the Conformation of Heparin by1H and13C NMR Spectroscopy". Macromolecules. 12 (5): 1001–1007. Bibcode:1979MaMol..12.1001G. doi:10.1021/ma60071a044. ISSN 0024-9297.

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Sanz A. "Coroner's office investigates infant deaths". WTHR NBC News. Archived from the original on 29 June 2011.