Huntingtin (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Huntingtin" in English language version.

refsWebsite

Global rank English rank

54nih.gov

4^th place

40doi.org

2^nd place

12semanticscholar.org

11^th place

8^th place

8harvard.edu

18^th place

17^th place

2ensembl.org

1,626^th place

1,007^th place

2handle.net

102^nd place

76^th place

1medlineplus.gov

1,581^st place

1,299^th place

1web.archive.org

1^st place

doi.org (Global: 2^nd place; English: 2^nd place)

Huntington's Disease Collaborative Research Group (Mar 1993). "A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group". Cell. 72 (6): 971–983. doi:10.1016/0092-8674(93)90585-E. hdl:2027.42/30901. PMID 8458085. S2CID 802885.
Choi YB, Kadakkuzha BM, Liu XA, Akhmedov K, Kandel ER, Puthanveettil SV (July 23, 2014). "Huntingtin is critical both pre- and postsynaptically for long-term learning-related synaptic plasticity in Aplysia". PLOS ONE. 9 (7) e103004. Bibcode:2014PLoSO...9j3004C. doi:10.1371/journal.pone.0103004. PMC 4108396. PMID 25054562.
Nasir J, Floresco SB, O'Kusky JR, Diewert VM, Richman JM, Zeisler J, et al. (Jun 1995). "Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes". Cell. 81 (5): 811–823. doi:10.1016/0092-8674(95)90542-1. PMID 7774020. S2CID 16835259.
Nance MA, Mathias-Hagen V, Breningstall G, Wick MJ, McGlennen RC (Jan 1999). "Analysis of a very large trinucleotide repeat in a patient with juvenile Huntington's disease". Neurology. 52 (2): 392–394. doi:10.1212/wnl.52.2.392. PMID 9932964. S2CID 33091017.
Guo Q, Huang B, Cheng J, Seefelder M, Engler T, Pfeifer G, et al. (Mar 2018). "The cryo-electron microscopy structure of huntingtin". Nature. 555 (7694): 117–120. Bibcode:2018Natur.555..117G. doi:10.1038/nature25502. PMC 5837020. PMID 29466333.
Truant R, Harding RJ, Neuman K, Maiuri T (November 2024). "Revisiting huntingtin activity and localization signals in the context of protein structure". Journal of Huntington's Disease. 13 (4): 419–430. doi:10.1177/18796397241295303. PMID 39973382.
Vitet H, Brandt V, Saudou F (August 2020). "Traffic signaling: new functions of huntingtin and axonal transport in neurological disease". Current Opinion in Neurobiology. 63: 122–130. doi:10.1016/j.conb.2020.04.001. PMID 32408142. S2CID 218596089.
Cattaneo E, Zuccato C, Tartari M (December 2005). "Normal huntingtin function: an alternative approach to Huntington's disease". Nature Reviews. Neuroscience. 6 (12): 919–930. doi:10.1038/nrn1806. PMID 16288298. S2CID 10119487.
Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, et al. (July 2001). "Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease". Science. 293 (5529). New York, N.Y.: 493–498. doi:10.1126/science.1059581. PMID 11408619. S2CID 20703272.
Hoffner G, Kahlem P, Djian P (March 2002). "Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: relevance to Huntington's disease". Journal of Cell Science. 115 (Pt 5): 941–948. doi:10.1242/jcs.115.5.941. PMID 11870213.
DiFiglia M, Sapp E, Chase K, Schwarz C, Meloni A, Young C, et al. (May 1995). "Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons". Neuron. 14 (5): 1075–1081. doi:10.1016/0896-6273(95)90346-1. PMID 7748555. S2CID 18071283.
Velier J, Kim M, Schwarz C, Kim TW, Sapp E, Chase K, et al. (July 1998). "Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways". Experimental Neurology. 152 (1): 34–40. doi:10.1006/exnr.1998.6832. PMID 9682010. S2CID 36726422.
Waelter S, Scherzinger E, Hasenbank R, Nordhoff E, Lurz R, Goehler H, et al. (August 2001). "The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis". Human Molecular Genetics. 10 (17): 1807–1817. doi:10.1093/hmg/10.17.1807. PMID 11532990.
Elias S, McGuire JR, Yu H, Humbert S (May 2015). "Huntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKC". PLOS Biology. 13 (5) e1002142. doi:10.1371/journal.pbio.1002142. PMC 4420272. PMID 25942483.
Harjes P, Wanker EE (Aug 2003). "The hunt for huntingtin function: interaction partners tell many different stories". Trends in Biochemical Sciences. 28 (8): 425–433. doi:10.1016/S0968-0004(03)00168-3. PMID 12932731.
Goehler H, Lalowski M, Stelzl U, Waelter S, Stroedicke M, Worm U, et al. (Sep 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular Cell. 15 (6): 853–865. doi:10.1016/j.molcel.2004.09.016. PMID 15383276.
Wanker EE, Rovira C, Scherzinger E, Hasenbank R, Wälter S, Tait D, et al. (Mar 1997). "HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system". Human Molecular Genetics. 6 (3): 487–495. doi:10.1093/hmg/6.3.487. PMID 9147654.
Liu YF, Deth RC, Devys D (Mar 1997). "SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes". The Journal of Biological Chemistry. 272 (13): 8121–8124. doi:10.1074/jbc.272.13.8121. PMID 9079622.
Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, Gohler H, et al. (Jun 2000). "The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription". Proceedings of the National Academy of Sciences of the United States of America. 97 (12): 6763–6768. Bibcode:2000PNAS...97.6763S. doi:10.1073/pnas.100110097. PMC 18731. PMID 10823891.
Modregger J, DiProspero NA, Charles V, Tagle DA, Plomann M (Oct 2002). "PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains". Human Molecular Genetics. 11 (21): 2547–2558. doi:10.1093/hmg/11.21.2547. PMID 12354780.
Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, et al. (Oct 1998). "SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates". Molecular Cell. 2 (4): 427–436. doi:10.1016/S1097-2765(00)80142-2. PMID 9809064.
Li SH, Cheng AL, Zhou H, Lam S, Rao M, Li H, et al. (Mar 2002). "Interaction of Huntington disease protein with transcriptional activator Sp1". Molecular and Cellular Biology. 22 (5): 1277–1287. doi:10.1128/MCB.22.5.1277-1287.2002. PMC 134707. PMID 11839795.
Kalchman MA, Graham RK, Xia G, Koide HB, Hodgson JG, Graham KC, et al. (Aug 1996). "Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme". The Journal of Biological Chemistry. 271 (32): 19385–19394. doi:10.1074/jbc.271.32.19385. PMID 8702625.
Liu YF, Dorow D, Marshall J (Jun 2000). "Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin". The Journal of Biological Chemistry. 275 (25): 19035–19040. doi:10.1074/jbc.C000180200. PMID 10801775.
Hattula K, Peränen J (2000). "FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis". Current Biology. 10 (24): 1603–1606. Bibcode:2000CBio...10.1603H. doi:10.1016/S0960-9822(00)00864-2. PMID 11137014. S2CID 12836037.
Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics. 7 (9): 1463–1474. doi:10.1093/hmg/7.9.1463. PMID 9700202.
Holbert S, Dedeoglu A, Humbert S, Saudou F, Ferrante RJ, Néri C (Mar 2003). "Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2712–2717. Bibcode:2003PNAS..100.2712H. doi:10.1073/pnas.0437967100. PMC 151406. PMID 12604778.
Singaraja RR, Hadano S, Metzler M, Givan S, Wellington CL, Warby S, et al. (Nov 2002). "HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis". Human Molecular Genetics. 11 (23): 2815–2828. doi:10.1093/hmg/11.23.2815. PMID 12393793.
Walker FO (Jan 2007). "Huntington's disease". Lancet. 369 (9557). London, England: 218–228. doi:10.1016/S0140-6736(07)60111-1. PMID 17240289. S2CID 46151626.
Chong SS, Almqvist E, Telenius H, LaTray L, Nichol K, Bourdelat-Parks B, et al. (Feb 1997). "Contribution of DNA sequence and CAG size to mutation frequencies of intermediate alleles for Huntington disease: evidence from single sperm analyses". Human Molecular Genetics. 6 (2): 301–309. doi:10.1093/hmg/6.2.301. PMID 9063751.
Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, Bondulich MK, et al. (Feb 2013). "Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease". Proceedings of the National Academy of Sciences of the United States of America. 110 (6): 2366–2370. Bibcode:2013PNAS..110.2366S. doi:10.1073/pnas.1221891110. hdl:1721.1/79814. PMC 3568346. PMID 23341618.
Davies SW, Turmaine M, Cozens BA, DiFiglia M, Sharp AH, Ross CA, et al. (Aug 1997). "Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation". Cell. 90 (3): 537–548. doi:10.1016/S0092-8674(00)80513-9. PMID 9267033. S2CID 549691.
Arrasate M, Mitra S, Schweitzer ES, Segal MR, Finkbeiner S (Oct 2004). "Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death". Nature. 431 (7010): 805–810. Bibcode:2004Natur.431..805A. doi:10.1038/nature02998. PMID 15483602.
Sahl SJ, Lau L, Vonk WI, Weiss LE, Frydman J, Moerner WE (2016). "Delayed Emergence of Subdiffraction-Sized Mutant Huntingtin Fibrils Following Inclusion Body Formation". Quarterly Reviews of Biophysics. 49 e2. doi:10.1017/S0033583515000219. PMC 4785097. PMID 26350150.
Orr HT (Oct 2004). "Neurodegenerative disease: neuron protection agency". Nature. 431 (7010): 747–748. Bibcode:2004Natur.431..747O. doi:10.1038/431747a. PMID 15483586. S2CID 285829.
Murmann AE, Patel M, Jeong SY, Bartom ET, Jennifer Morton A, Peter ME (2022). "The length of uninterrupted CAG repeats in stem regions of repeat disease associated hairpins determines the amount of short CAG oligonucleotides that are toxic to cells through RNA interference". Cell Death & Disease. 13 (12) 1078. doi:10.1038/s41419-022-05494-1. PMC 9803637. PMID 36585400.
Handsaker RE, Kashin S, Reed NM, Tan S, Lee WS, McDonald TM, et al. (February 2025). "Long somatic DNA-repeat expansion drives neurodegeneration in Huntington's disease". Cell. 188 (3): 623–639.e19. doi:10.1016/j.cell.2024.11.038. PMC 11822645. PMID 39824182.
Liu Z, Zhou T, Ziegler AC, Dimitrion P, Zuo L (2017). "Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications". Oxidative Medicine and Cellular Longevity. 2017 2525967. doi:10.1155/2017/2525967. PMC 5529664. PMID 28785371.
Maiuri T, Mocle AJ, Hung CL, Xia J, van Roon-Mom WM, Truant R (25 December 2016). "Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex". Human Molecular Genetics. 26 (2): 395–406. doi:10.1093/hmg/ddw395. PMID 28017939.
Ayala-Peña S (September 2013). "Role of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesis". Free Radical Biology & Medicine. 62: 102–110. doi:10.1016/j.freeradbiomed.2013.04.017. PMC 3722255. PMID 23602907.

ensembl.org (Global: 1,626^th place; English: 1,007^th place)

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000197386 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000029104 – Ensembl, May 2017

handle.net (Global: 102^nd place; English: 76^th place)

hdl.handle.net

Huntington's Disease Collaborative Research Group (Mar 1993). "A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group". Cell. 72 (6): 971–983. doi:10.1016/0092-8674(93)90585-E. hdl:2027.42/30901. PMID 8458085. S2CID 802885.
Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, Bondulich MK, et al. (Feb 2013). "Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease". Proceedings of the National Academy of Sciences of the United States of America. 110 (6): 2366–2370. Bibcode:2013PNAS..110.2366S. doi:10.1073/pnas.1221891110. hdl:1721.1/79814. PMC 3568346. PMID 23341618.

harvard.edu (Global: 18^th place; English: 17^th place)

ui.adsabs.harvard.edu

Choi YB, Kadakkuzha BM, Liu XA, Akhmedov K, Kandel ER, Puthanveettil SV (July 23, 2014). "Huntingtin is critical both pre- and postsynaptically for long-term learning-related synaptic plasticity in Aplysia". PLOS ONE. 9 (7) e103004. Bibcode:2014PLoSO...9j3004C. doi:10.1371/journal.pone.0103004. PMC 4108396. PMID 25054562.
Guo Q, Huang B, Cheng J, Seefelder M, Engler T, Pfeifer G, et al. (Mar 2018). "The cryo-electron microscopy structure of huntingtin". Nature. 555 (7694): 117–120. Bibcode:2018Natur.555..117G. doi:10.1038/nature25502. PMC 5837020. PMID 29466333.
Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, Gohler H, et al. (Jun 2000). "The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription". Proceedings of the National Academy of Sciences of the United States of America. 97 (12): 6763–6768. Bibcode:2000PNAS...97.6763S. doi:10.1073/pnas.100110097. PMC 18731. PMID 10823891.
Hattula K, Peränen J (2000). "FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis". Current Biology. 10 (24): 1603–1606. Bibcode:2000CBio...10.1603H. doi:10.1016/S0960-9822(00)00864-2. PMID 11137014. S2CID 12836037.
Holbert S, Dedeoglu A, Humbert S, Saudou F, Ferrante RJ, Néri C (Mar 2003). "Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2712–2717. Bibcode:2003PNAS..100.2712H. doi:10.1073/pnas.0437967100. PMC 151406. PMID 12604778.
Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, Bondulich MK, et al. (Feb 2013). "Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease". Proceedings of the National Academy of Sciences of the United States of America. 110 (6): 2366–2370. Bibcode:2013PNAS..110.2366S. doi:10.1073/pnas.1221891110. hdl:1721.1/79814. PMC 3568346. PMID 23341618.
Arrasate M, Mitra S, Schweitzer ES, Segal MR, Finkbeiner S (Oct 2004). "Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death". Nature. 431 (7010): 805–810. Bibcode:2004Natur.431..805A. doi:10.1038/nature02998. PMID 15483602.
Orr HT (Oct 2004). "Neurodegenerative disease: neuron protection agency". Nature. 431 (7010): 747–748. Bibcode:2004Natur.431..747O. doi:10.1038/431747a. PMID 15483586. S2CID 285829.

medlineplus.gov (Global: 1,581^st place; English: 1,299^th place)

"HTT gene". Archived from the original on 2016-02-02. Retrieved 2016-02-18.

nih.gov (Global: 4^th place; English: 4^th place)

pubmed.ncbi.nlm.nih.gov

Huntington's Disease Collaborative Research Group (Mar 1993). "A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group". Cell. 72 (6): 971–983. doi:10.1016/0092-8674(93)90585-E. hdl:2027.42/30901. PMID 8458085. S2CID 802885.
Choi YB, Kadakkuzha BM, Liu XA, Akhmedov K, Kandel ER, Puthanveettil SV (July 23, 2014). "Huntingtin is critical both pre- and postsynaptically for long-term learning-related synaptic plasticity in Aplysia". PLOS ONE. 9 (7) e103004. Bibcode:2014PLoSO...9j3004C. doi:10.1371/journal.pone.0103004. PMC 4108396. PMID 25054562.
Nasir J, Floresco SB, O'Kusky JR, Diewert VM, Richman JM, Zeisler J, et al. (Jun 1995). "Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes". Cell. 81 (5): 811–823. doi:10.1016/0092-8674(95)90542-1. PMID 7774020. S2CID 16835259.
Nance MA, Mathias-Hagen V, Breningstall G, Wick MJ, McGlennen RC (Jan 1999). "Analysis of a very large trinucleotide repeat in a patient with juvenile Huntington's disease". Neurology. 52 (2): 392–394. doi:10.1212/wnl.52.2.392. PMID 9932964. S2CID 33091017.
Guo Q, Huang B, Cheng J, Seefelder M, Engler T, Pfeifer G, et al. (Mar 2018). "The cryo-electron microscopy structure of huntingtin". Nature. 555 (7694): 117–120. Bibcode:2018Natur.555..117G. doi:10.1038/nature25502. PMC 5837020. PMID 29466333.
Truant R, Harding RJ, Neuman K, Maiuri T (November 2024). "Revisiting huntingtin activity and localization signals in the context of protein structure". Journal of Huntington's Disease. 13 (4): 419–430. doi:10.1177/18796397241295303. PMID 39973382.
Vitet H, Brandt V, Saudou F (August 2020). "Traffic signaling: new functions of huntingtin and axonal transport in neurological disease". Current Opinion in Neurobiology. 63: 122–130. doi:10.1016/j.conb.2020.04.001. PMID 32408142. S2CID 218596089.
Cattaneo E, Zuccato C, Tartari M (December 2005). "Normal huntingtin function: an alternative approach to Huntington's disease". Nature Reviews. Neuroscience. 6 (12): 919–930. doi:10.1038/nrn1806. PMID 16288298. S2CID 10119487.
Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, et al. (July 2001). "Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease". Science. 293 (5529). New York, N.Y.: 493–498. doi:10.1126/science.1059581. PMID 11408619. S2CID 20703272.
Hoffner G, Kahlem P, Djian P (March 2002). "Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: relevance to Huntington's disease". Journal of Cell Science. 115 (Pt 5): 941–948. doi:10.1242/jcs.115.5.941. PMID 11870213.
DiFiglia M, Sapp E, Chase K, Schwarz C, Meloni A, Young C, et al. (May 1995). "Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons". Neuron. 14 (5): 1075–1081. doi:10.1016/0896-6273(95)90346-1. PMID 7748555. S2CID 18071283.
Velier J, Kim M, Schwarz C, Kim TW, Sapp E, Chase K, et al. (July 1998). "Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways". Experimental Neurology. 152 (1): 34–40. doi:10.1006/exnr.1998.6832. PMID 9682010. S2CID 36726422.
Waelter S, Scherzinger E, Hasenbank R, Nordhoff E, Lurz R, Goehler H, et al. (August 2001). "The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis". Human Molecular Genetics. 10 (17): 1807–1817. doi:10.1093/hmg/10.17.1807. PMID 11532990.
Elias S, McGuire JR, Yu H, Humbert S (May 2015). "Huntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKC". PLOS Biology. 13 (5) e1002142. doi:10.1371/journal.pbio.1002142. PMC 4420272. PMID 25942483.
Harjes P, Wanker EE (Aug 2003). "The hunt for huntingtin function: interaction partners tell many different stories". Trends in Biochemical Sciences. 28 (8): 425–433. doi:10.1016/S0968-0004(03)00168-3. PMID 12932731.
Goehler H, Lalowski M, Stelzl U, Waelter S, Stroedicke M, Worm U, et al. (Sep 2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Molecular Cell. 15 (6): 853–865. doi:10.1016/j.molcel.2004.09.016. PMID 15383276.
Wanker EE, Rovira C, Scherzinger E, Hasenbank R, Wälter S, Tait D, et al. (Mar 1997). "HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system". Human Molecular Genetics. 6 (3): 487–495. doi:10.1093/hmg/6.3.487. PMID 9147654.
Liu YF, Deth RC, Devys D (Mar 1997). "SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes". The Journal of Biological Chemistry. 272 (13): 8121–8124. doi:10.1074/jbc.272.13.8121. PMID 9079622.
Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, Gohler H, et al. (Jun 2000). "The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription". Proceedings of the National Academy of Sciences of the United States of America. 97 (12): 6763–6768. Bibcode:2000PNAS...97.6763S. doi:10.1073/pnas.100110097. PMC 18731. PMID 10823891.
Modregger J, DiProspero NA, Charles V, Tagle DA, Plomann M (Oct 2002). "PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains". Human Molecular Genetics. 11 (21): 2547–2558. doi:10.1093/hmg/11.21.2547. PMID 12354780.
Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, et al. (Oct 1998). "SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates". Molecular Cell. 2 (4): 427–436. doi:10.1016/S1097-2765(00)80142-2. PMID 9809064.
Li SH, Cheng AL, Zhou H, Lam S, Rao M, Li H, et al. (Mar 2002). "Interaction of Huntington disease protein with transcriptional activator Sp1". Molecular and Cellular Biology. 22 (5): 1277–1287. doi:10.1128/MCB.22.5.1277-1287.2002. PMC 134707. PMID 11839795.
Kalchman MA, Graham RK, Xia G, Koide HB, Hodgson JG, Graham KC, et al. (Aug 1996). "Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme". The Journal of Biological Chemistry. 271 (32): 19385–19394. doi:10.1074/jbc.271.32.19385. PMID 8702625.
Liu YF, Dorow D, Marshall J (Jun 2000). "Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin". The Journal of Biological Chemistry. 275 (25): 19035–19040. doi:10.1074/jbc.C000180200. PMID 10801775.
Hattula K, Peränen J (2000). "FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis". Current Biology. 10 (24): 1603–1606. Bibcode:2000CBio...10.1603H. doi:10.1016/S0960-9822(00)00864-2. PMID 11137014. S2CID 12836037.
Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics. 7 (9): 1463–1474. doi:10.1093/hmg/7.9.1463. PMID 9700202.
Holbert S, Dedeoglu A, Humbert S, Saudou F, Ferrante RJ, Néri C (Mar 2003). "Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2712–2717. Bibcode:2003PNAS..100.2712H. doi:10.1073/pnas.0437967100. PMC 151406. PMID 12604778.
Singaraja RR, Hadano S, Metzler M, Givan S, Wellington CL, Warby S, et al. (Nov 2002). "HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis". Human Molecular Genetics. 11 (23): 2815–2828. doi:10.1093/hmg/11.23.2815. PMID 12393793.
Walker FO (Jan 2007). "Huntington's disease". Lancet. 369 (9557). London, England: 218–228. doi:10.1016/S0140-6736(07)60111-1. PMID 17240289. S2CID 46151626.
Chong SS, Almqvist E, Telenius H, LaTray L, Nichol K, Bourdelat-Parks B, et al. (Feb 1997). "Contribution of DNA sequence and CAG size to mutation frequencies of intermediate alleles for Huntington disease: evidence from single sperm analyses". Human Molecular Genetics. 6 (2): 301–309. doi:10.1093/hmg/6.2.301. PMID 9063751.
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ncbi.nlm.nih.gov

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semanticscholar.org (Global: 11^th place; English: 8^th place)

api.semanticscholar.org

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"HTT gene". Archived from the original on 2016-02-02. Retrieved 2016-02-18.

Huntingtin (English Wikipedia)

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