Induced pluripotent stem cell (English Wikipedia)

Takahashi K, Yamanaka S (August 2006). "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors". Cell. 126 (4): 663–76. doi:10.1016/j.cell.2006.07.024. hdl:2433/159777. PMID 16904174.
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S (November 2007). "Induction of pluripotent stem cells from adult human fibroblasts by defined factors". Cell. 131 (5): 861–72. doi:10.1016/j.cell.2007.11.019. hdl:2433/49782. PMID 18035408.
Maekawa M, Yamaguchi K, Nakamura T, Shibukawa R, Kodanaka I, Ichisaka T, et al. (June 2011). "Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1". Nature. 474 (7350): 225–9. doi:10.1038/nature10106. hdl:2433/141930. PMID 21654807. S2CID 4428172.
Luo M, Ling T, Xie W, Sun H, Zhou Y, Zhu Q, et al. (July 2013). "NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells". Stem Cells. 31 (7): 1278–86. doi:10.1002/stem.1374. hdl:10397/18487. PMID 23533168. S2CID 206512562.
Aoi T, Yae K, Nakagawa M, Ichisaka T, Okita K, Takahashi K, et al. (August 2008). "Generation of pluripotent stem cells from adult mouse liver and stomach cells". Science. 321 (5889): 699–702. Bibcode:2008Sci...321..699A. doi:10.1126/science.1154884. hdl:2433/124215. PMID 18276851. S2CID 52869734.

harvard.edu (Global: 18^th place; English: 17^th place)

ui.adsabs.harvard.edu

Klimanskaya I, Chung Y, Becker S, Lu SJ, Lanza R (November 2006). "Human embryonic stem cell lines derived from single blastomeres". Nature. 444 (7118): 481–5. Bibcode:2006Natur.444..481K. doi:10.1038/nature05142. PMID 16929302. S2CID 84792371.
Yamanaka S (December 2013). "The winding road to pluripotency (Nobel Lecture)". Angewandte Chemie. 52 (52): 13900–9. Bibcode:2013ACIE...5213900Y. doi:10.1002/anie.201306721. PMID 24255017.
Okita K, Ichisaka T, Yamanaka S (July 2007). "Generation of germline-competent induced pluripotent stem cells". Nature. 448 (7151): 313–7. Bibcode:2007Natur.448..313O. doi:10.1038/nature05934. PMID 17554338. S2CID 459050.
Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, et al. (July 2007). "In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state". Nature. 448 (7151): 318–24. Bibcode:2007Natur.448..318W. doi:10.1038/nature05944. PMID 17554336. S2CID 4377572.
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, et al. (December 2007). "Induced pluripotent stem cell lines derived from human somatic cells". Science. 318 (5858): 1917–20. Bibcode:2007Sci...318.1917Y. doi:10.1126/science.1151526. PMID 18029452. S2CID 86129154.
Ali PS, Ghoshdastider U, Hoffmann J, Brutschy B, Filipek S (November 2012). "Recognition of the let-7g miRNA precursor by human Lin28B". FEBS Letters. 586 (22): 3986–90. Bibcode:2012FEBSL.586.3986S. doi:10.1016/j.febslet.2012.09.034. PMID 23063642. S2CID 28899778.
Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, et al. (October 2013). "Deterministic direct reprogramming of somatic cells to pluripotency". Nature. 502 (7469): 65–70. Bibcode:2013Natur.502...65R. doi:10.1038/nature12587. PMID 24048479. S2CID 4386833.
Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S (November 2008). "Generation of mouse induced pluripotent stem cells without viral vectors". Science. 322 (5903): 949–53. Bibcode:2008Sci...322..949O. doi:10.1126/science.1164270. PMID 18845712. S2CID 23735743.
Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K (November 2008). "Induced pluripotent stem cells generated without viral integration". Science. 322 (5903): 945–9. Bibcode:2008Sci...322..945S. doi:10.1126/science.1162494. PMC 3987909. PMID 18818365.
Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hämäläinen R, et al. (April 2009). "piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells". Nature. 458 (7239): 766–70. Bibcode:2009Natur.458..766W. doi:10.1038/nature07863. PMC 3758996. PMID 19252478.
Marión RM, Strati K, Li H, Murga M, Blanco R, Ortega S, et al. (August 2009). "A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity". Nature. 460 (7259): 1149–53. Bibcode:2009Natur.460.1149M. doi:10.1038/nature08287. PMC 3624089. PMID 19668189.
Zhao XY, Li W, Lv Z, Liu L, Tong M, Hai T, et al. (September 2009). "iPS cells produce viable mice through tetraploid complementation". Nature. 461 (7260): 86–90. Bibcode:2009Natur.461...86Z. doi:10.1038/nature08267. PMID 19672241. S2CID 205217762.
Hou P, Li Y, Zhang X, Liu C, Guan J, Li H, et al. (August 2013). "Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds". Science. 341 (6146): 651–4. Bibcode:2013Sci...341..651H. doi:10.1126/science.1239278. PMID 23868920. S2CID 45685692.
Boland MJ, Hazen JL, Nazor KL, Rodriguez AR, Gifford W, Martin G, et al. (September 2009). "Adult mice generated from induced pluripotent stem cells". Nature. 461 (7260): 91–4. Bibcode:2009Natur.461...91B. doi:10.1038/nature08310. PMID 19672243. S2CID 4423755.
Lister R, Pelizzola M, Kida YS, Hawkins RD, Nery JR, Hon G, et al. (March 2011). "Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells". Nature. 471 (7336): 68–73. Bibcode:2011Natur.471...68L. doi:10.1038/nature09798. PMC 3100360. PMID 21289626.
Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, et al. (October 2011). "Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice". Proceedings of the National Academy of Sciences of the United States of America. 108 (40): 16825–30. Bibcode:2011PNAS..10816825N. doi:10.1073/pnas.1108077108. PMC 3189018. PMID 21949375.
Aoi T, Yae K, Nakagawa M, Ichisaka T, Okita K, Takahashi K, et al. (August 2008). "Generation of pluripotent stem cells from adult mouse liver and stomach cells". Science. 321 (5889): 699–702. Bibcode:2008Sci...321..699A. doi:10.1126/science.1154884. hdl:2433/124215. PMID 18276851. S2CID 52869734.
Araki R, Uda M, Hoki Y, Sunayama M, Nakamura M, Ando S, et al. (February 2013). "Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells". Nature. 494 (7435): 100–4. Bibcode:2013Natur.494..100A. doi:10.1038/nature11807. PMID 23302801. S2CID 205232231.
Shalom-Feuerstein R, Serror L, Aberdam E, Müller FJ, van Bokhoven H, Wiman KG, et al. (February 2013). "Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET". Proceedings of the National Academy of Sciences of the United States of America. 110 (6): 2152–6. Bibcode:2013PNAS..110.2152S. doi:10.1073/pnas.1201753109. PMC 3568301. PMID 23355677.
Takebe T, Sekine K, Enomura M, Koike H, Kimura M, Ogaeri T, et al. (July 2013). "Vascularized and functional human liver from an iPSC-derived organ bud transplant". Nature. 499 (7459): 481–4. Bibcode:2013Natur.499..481T. doi:10.1038/nature12271. PMID 23823721. S2CID 4423004.
Chen Y, Lüttmann FF, Schoger E, Schöler HR, Zelarayán LC, Kim KP, et al. (September 2021). "Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice". Science. 373 (6562): 1537–1540. Bibcode:2021Sci...373.1537C. doi:10.1126/science.abg5159. PMID 34554778. S2CID 237617229.
Yazawa M, Hsueh B, Jia X, Pasca AM, Bernstein JA, Hallmayer J, Dolmetsch RE (March 2011). "Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome". Nature. 471 (7337): 230–4. Bibcode:2011Natur.471..230Y. doi:10.1038/nature09855. PMC 3077925. PMID 21307850.
Itzhaki I, Maizels L, Huber I, Zwi-Dantsis L, Caspi O, Winterstern A, et al. (March 2011). "Modelling the long QT syndrome with induced pluripotent stem cells". Nature. 471 (7337): 225–9. Bibcode:2011Natur.471..225I. doi:10.1038/nature09747. PMID 21240260. S2CID 4384573.
Wei H, Wang C, Guo R, Takahashi K, Naruse K (December 2019). "Development of a model of ischemic heart disease using cardiomyocytes differentiated from human induced pluripotent stem cells". Biochemical and Biophysical Research Communications. 520 (3): 600–605. Bibcode:2019BBRC..520..600W. doi:10.1016/j.bbrc.2019.09.119. PMID 31623826.
Sarkar TJ, Quarta M, Mukherjee S, Colville A, Paine P, Doan L, et al. (March 2020). "Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells". Nature Communications. 11 (1) 1545. Bibcode:2020NatCo..11.1545S. doi:10.1038/s41467-020-15174-3. PMC 7093390. PMID 32210226.

ipscell.com (Global: low place; English: low place)

Knoepfler P (25 January 2021). "What are induced pluripotent stem cells or IPS cells & clinical prospects?". The Niche. Retrieved 7 February 2021.

j-cast.com (Global: 1,374^th place; English: low place)

"山中教授の「iPS細胞」ってiPod のパクリ!?流行らせたいと頭小文字". J-CASTニュース. 9 October 2012. Retrieved 28 April 2013.

japantimes.co.jp (Global: 389^th place; English: 273^rd place)

"First serious adverse reaction to iPS-derived retinal cell transplant reported". The Japan Times Online. 17 January 2018. Archived from the original on 27 January 2018. Retrieved 27 January 2018.

latimes.com (Global: 22^nd place; English: 19^th place)

Kaplan K (6 March 2009). "Cancer threat removed from stem cells, scientists say". Los Angeles Times.

mpg.de (Global: 1,624^th place; English: 1,592^nd place)

mpi-muenster.mpg.de

Quality of induced pluripotent stem cells is dramatically enhanced by omitting what was thought to be the most crucial reprogramming factor Oct4 is not only unnecessary but damaging during generation of mouse induced pluripotent stem cells (iPSCs)

nature.com (Global: 234^th place; English: 397^th place)

Cyranoski D (18 July 2013). "Stem cells reprogrammed using chemicals alone". Nature News. doi:10.1038/nature.2013.13416. S2CID 88247014. Retrieved 22 July 2013.
David Cyranoski for Nature News. January 29, 2014 Acid bath offers easy path to stem cells
Baker M (3 July 2013). "Miniature human liver grown in mice". Nature. doi:10.1038/nature.2013.13324. S2CID 87064973. Retrieved 19 July 2013.

newatlas.com (Global: 5,636^th place; English: 3,692^nd place)

Haridy R (23 October 2017). "Anti-Aging Stem Cell Treatment Proves Successful in Early Human Trials". New Atlas.

nih.gov (Global: 4^th place; English: 4^th place)

pubmed.ncbi.nlm.nih.gov

Takahashi K, Yamanaka S (August 2006). "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors". Cell. 126 (4): 663–76. doi:10.1016/j.cell.2006.07.024. hdl:2433/159777. PMID 16904174.
Mahla RS (2016). "Stem Cells Applications in Regenerative Medicine and Disease Therapeutics". International Journal of Cell Biology. 2016 6940283. doi:10.1155/2016/6940283. PMC 4969512. PMID 27516776.
Klimanskaya I, Chung Y, Becker S, Lu SJ, Lanza R (November 2006). "Human embryonic stem cell lines derived from single blastomeres". Nature. 444 (7118): 481–5. Bibcode:2006Natur.444..481K. doi:10.1038/nature05142. PMID 16929302. S2CID 84792371.
Hockemeyer D, Jaenisch R (May 2016). "Induced Pluripotent Stem Cells Meet Genome Editing". Cell Stem Cell. 18 (5): 573–86. doi:10.1016/j.stem.2016.04.013. PMC 4871596. PMID 27152442.
Eguizabal C, Aran B, Chuva de Sousa Lopes SM, Geens M, Heindryckx B, Panula S, Popovic M, Vassena R, Veiga A (2019). "Two decades of embryonic stem cells: a historical overview". Human Reproduction Open. 2019 (1) hoy024. doi:10.1093/hropen/hoy024. PMC 6396646. PMID 30895264.
Yamanaka S (December 2013). "The winding road to pluripotency (Nobel Lecture)". Angewandte Chemie. 52 (52): 13900–9. Bibcode:2013ACIE...5213900Y. doi:10.1002/anie.201306721. PMID 24255017.
Guo XL, Chen JS (2015). "Research on induced pluripotent stem cells and the application in ocular tissues". International Journal of Ophthalmology. 8 (4): 818–25. doi:10.3980/j.issn.2222-3959.2015.04.31. PMC 4539634. PMID 26309885.
Thornton, Christopher D.; Fielding, Stuart; Karbowniczek, Kinga; Roig-Merino, Alicia; Burrows, Alysha E.; FitzPatrick, Lorna M.; Sharaireh, Aseel; Tite, John P.; Mole, Sara E.; Harbottle, Richard P.; Caproni, Lisa J.; McKay, Tristan R. (10 December 2021). "Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors". Molecular Therapy - Methods & Clinical Development. 23: 348–358. doi:10.1016/j.omtm.2021.09.018. ISSN 2329-0501. PMC 8546411. PMID 34729381.
Okita K, Ichisaka T, Yamanaka S (July 2007). "Generation of germline-competent induced pluripotent stem cells". Nature. 448 (7151): 313–7. Bibcode:2007Natur.448..313O. doi:10.1038/nature05934. PMID 17554338. S2CID 459050.
Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, et al. (July 2007). "In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state". Nature. 448 (7151): 318–24. Bibcode:2007Natur.448..318W. doi:10.1038/nature05944. PMID 17554336. S2CID 4377572.
Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, et al. (June 2007). "Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution". Cell Stem Cell. 1 (1): 55–70. doi:10.1016/j.stem.2007.05.014. PMID 18371336.
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S (November 2007). "Induction of pluripotent stem cells from adult human fibroblasts by defined factors". Cell. 131 (5): 861–72. doi:10.1016/j.cell.2007.11.019. hdl:2433/49782. PMID 18035408.
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, et al. (December 2007). "Induced pluripotent stem cell lines derived from human somatic cells". Science. 318 (5858): 1917–20. Bibcode:2007Sci...318.1917Y. doi:10.1126/science.1151526. PMID 18029452. S2CID 86129154.
Yamanaka S (July 2010). "Patient-specific pluripotent stem cells become even more accessible". Cell Stem Cell. 7 (1): 1–2. doi:10.1016/j.stem.2010.06.009. PMID 20621038.
Maherali N, Hochedlinger K (December 2008). "Guidelines and techniques for the generation of induced pluripotent stem cells". Cell Stem Cell. 3 (6): 595–605. doi:10.1016/j.stem.2008.11.008. PMID 19041776.
Maherali N, Ahfeldt T, Rigamonti A, Utikal J, Cowan C, Hochedlinger K (September 2008). "A high-efficiency system for the generation and study of human induced pluripotent stem cells". Cell Stem Cell. 3 (3): 340–5. doi:10.1016/j.stem.2008.08.003. PMC 3987901. PMID 18786420.
Aasen T, Raya A, Barrero MJ, Garreta E, Consiglio A, Gonzalez F, et al. (November 2008). "Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes". Nature Biotechnology. 26 (11): 1276–84. doi:10.1038/nbt.1503. PMID 18931654. S2CID 205274019.
Staerk J, Dawlaty MM, Gao Q, Maetzel D, Hanna J, Sommer CA, et al. (July 2010). "Reprogramming of human peripheral blood cells to induced pluripotent stem cells". Cell Stem Cell. 7 (1): 20–4. doi:10.1016/j.stem.2010.06.002. PMC 2917234. PMID 20621045.
Loh YH, Hartung O, Li H, Guo C, Sahalie JM, Manos PD, et al. (July 2010). "Reprogramming of T cells from human peripheral blood". Cell Stem Cell. 7 (1): 15–9. doi:10.1016/j.stem.2010.06.004. PMC 2913590. PMID 20621044.
Zhou T, Benda C, Dunzinger S, Huang Y, Ho JC, Yang J, et al. (December 2012). "Generation of human induced pluripotent stem cells from urine samples". Nature Protocols. 7 (12): 2080–9. doi:10.1038/nprot.2012.115. PMID 23138349. S2CID 205465442.
Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, Tan KY, et al. (August 2010). "Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells". Nature Biotechnology. 28 (8): 848–55. doi:10.1038/nbt.1667. PMC 3148605. PMID 20644536.
Velychko S, Adachi K, Kim KP, Hou Y, MacCarthy CM, Wu G, Schöler HR (December 2019). "Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs". Cell Stem Cell. 25 (6): 737–753.e4. doi:10.1016/j.stem.2019.10.002. PMC 6900749. PMID 31708402.
MacCarthy, Caitlin M.; Wu, Guangming; Malik, Vikas; Menuchin-Lasowski, Yotam; Velychko, Taras; Keshet, Gal; Fan, Rui; Bedzhov, Ivan; Church, George M.; Jauch, Ralf; Cojocaru, Vlad; Schöler, Hans R.; Velychko, Sergiy (December 2023). "Highly cooperative chimeric super-SOX induces naive pluripotency across species". Cell Stem Cell. 31 (1): 127–147.e9. doi:10.1016/j.stem.2023.11.010. PMID 38141611.
Ali PS, Ghoshdastider U, Hoffmann J, Brutschy B, Filipek S (November 2012). "Recognition of the let-7g miRNA precursor by human Lin28B". FEBS Letters. 586 (22): 3986–90. Bibcode:2012FEBSL.586.3986S. doi:10.1016/j.febslet.2012.09.034. PMID 23063642. S2CID 28899778.
Maekawa M, Yamaguchi K, Nakamura T, Shibukawa R, Kodanaka I, Ichisaka T, et al. (June 2011). "Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1". Nature. 474 (7350): 225–9. doi:10.1038/nature10106. hdl:2433/141930. PMID 21654807. S2CID 4428172.
Luo M, Ling T, Xie W, Sun H, Zhou Y, Zhu Q, et al. (July 2013). "NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells". Stem Cells. 31 (7): 1278–86. doi:10.1002/stem.1374. hdl:10397/18487. PMID 23533168. S2CID 206512562.
Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, et al. (October 2013). "Deterministic direct reprogramming of somatic cells to pluripotency". Nature. 502 (7469): 65–70. Bibcode:2013Natur.502...65R. doi:10.1038/nature12587. PMID 24048479. S2CID 4386833.
Selvaraj V, Plane JM, Williams AJ, Deng W (April 2010). "Switching cell fate: the remarkable rise of induced pluripotent stem cells and lineage reprogramming technologies". Trends in Biotechnology. 28 (4): 214–23. doi:10.1016/j.tibtech.2010.01.002. PMC 2843790. PMID 20149468.
Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S (November 2008). "Generation of mouse induced pluripotent stem cells without viral vectors". Science. 322 (5903): 949–53. Bibcode:2008Sci...322..949O. doi:10.1126/science.1164270. PMID 18845712. S2CID 23735743.
Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K (November 2008). "Induced pluripotent stem cells generated without viral integration". Science. 322 (5903): 945–9. Bibcode:2008Sci...322..945S. doi:10.1126/science.1162494. PMC 3987909. PMID 18818365.
Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hämäläinen R, et al. (April 2009). "piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells". Nature. 458 (7239): 766–70. Bibcode:2009Natur.458..766W. doi:10.1038/nature07863. PMC 3758996. PMID 19252478.
Marión RM, Strati K, Li H, Murga M, Blanco R, Ortega S, et al. (August 2009). "A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity". Nature. 460 (7259): 1149–53. Bibcode:2009Natur.460.1149M. doi:10.1038/nature08287. PMC 3624089. PMID 19668189.
Zhao XY, Li W, Lv Z, Liu L, Tong M, Hai T, et al. (September 2009). "iPS cells produce viable mice through tetraploid complementation". Nature. 461 (7260): 86–90. Bibcode:2009Natur.461...86Z. doi:10.1038/nature08267. PMID 19672241. S2CID 205217762.
Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, Chen AE, Melton DA (July 2008). "Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds". Nature Biotechnology. 26 (7): 795–7. doi:10.1038/nbt1418. PMC 6334647. PMID 18568017.
Shi Y, Desponts C, Do JT, Hahm HS, Schöler HR, Ding S (November 2008). "Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds". Cell Stem Cell. 3 (5): 568–74. doi:10.1016/j.stem.2008.10.004. PMID 18983970.
Hou P, Li Y, Zhang X, Liu C, Guan J, Li H, et al. (August 2013). "Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds". Science. 341 (6146): 651–4. Bibcode:2013Sci...341..651H. doi:10.1126/science.1239278. PMID 23868920. S2CID 45685692.
Lin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, et al. (November 2009). "A chemical platform for improved induction of human iPSCs". Nature Methods. 6 (11): 805–8. doi:10.1038/nmeth.1393. PMC 3724527. PMID 19838168.
Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, et al. (May 2009). "Generation of induced pluripotent stem cells using recombinant proteins". Cell Stem Cell. 4 (5): 381–4. doi:10.1016/j.stem.2009.04.005. PMC 10182564. PMID 19398399.
Zhou W, Freed CR (November 2009). "Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells". Stem Cells. 27 (11): 2667–74. doi:10.1002/stem.201. PMID 19697349. S2CID 41418742.
Bao X, Zhu X, Liao B, Benda C, Zhuang Q, Pei D, et al. (April 2013). "MicroRNAs in somatic cell reprogramming". Current Opinion in Cell Biology. 25 (2): 208–14. doi:10.1016/j.ceb.2012.12.004. PMID 23332905.
Judson RL, Babiarz JE, Venere M, Blelloch R (May 2009). "Embryonic stem cell-specific microRNAs promote induced pluripotency". Nature Biotechnology. 27 (5): 459–61. doi:10.1038/nbt.1535. PMC 2743930. PMID 19363475.
Guenther MG, Frampton GM, Soldner F, Hockemeyer D, Mitalipova M, Jaenisch R, Young RA (August 2010). "Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells". Cell Stem Cell. 7 (2): 249–57. doi:10.1016/j.stem.2010.06.015. PMC 3010384. PMID 20682450.
Kang L, Wang J, Zhang Y, Kou Z, Gao S (August 2009). "iPS cells can support full-term development of tetraploid blastocyst-complemented embryos". Cell Stem Cell. 5 (2): 135–8. doi:10.1016/j.stem.2009.07.001. PMID 19631602.
Boland MJ, Hazen JL, Nazor KL, Rodriguez AR, Gifford W, Martin G, et al. (September 2009). "Adult mice generated from induced pluripotent stem cells". Nature. 461 (7260): 91–4. Bibcode:2009Natur.461...91B. doi:10.1038/nature08310. PMID 19672243. S2CID 4423755.
Lister R, Pelizzola M, Kida YS, Hawkins RD, Nery JR, Hon G, et al. (March 2011). "Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells". Nature. 471 (7336): 68–73. Bibcode:2011Natur.471...68L. doi:10.1038/nature09798. PMC 3100360. PMID 21289626.
Knoepfler PS (May 2009). "Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine". Stem Cells. 27 (5): 1050–6. doi:10.1002/stem.37. PMC 2733374. PMID 19415771.
Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, et al. (October 2011). "Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice". Proceedings of the National Academy of Sciences of the United States of America. 108 (40): 16825–30. Bibcode:2011PNAS..10816825N. doi:10.1073/pnas.1108077108. PMC 3189018. PMID 21949375.
Nori S, Okada Y, Nishimura S, Sasaki T, Itakura G, Kobayashi Y, et al. (March 2015). "Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transition". Stem Cell Reports. 4 (3): 360–73. doi:10.1016/j.stemcr.2015.01.006. PMC 4375796. PMID 25684226.
Aoi T, Yae K, Nakagawa M, Ichisaka T, Okita K, Takahashi K, et al. (August 2008). "Generation of pluripotent stem cells from adult mouse liver and stomach cells". Science. 321 (5889): 699–702. Bibcode:2008Sci...321..699A. doi:10.1126/science.1154884. hdl:2433/124215. PMID 18276851. S2CID 52869734.
Gutierrez-Aranda I, Ramos-Mejia V, Bueno C, Munoz-Lopez M, Real PJ, Mácia A, et al. (September 2010). "Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection". Stem Cells. 28 (9): 1568–70. doi:10.1002/stem.471. PMC 2996086. PMID 20641038.
Zhao T, Zhang ZN, Rong Z, Xu Y (May 2011). "Immunogenicity of induced pluripotent stem cells". Nature. 474 (7350): 212–5. CiteSeerX 10.1.1.864.8029. doi:10.1038/nature10135. PMID 21572395. S2CID 4416964.
Araki R, Uda M, Hoki Y, Sunayama M, Nakamura M, Ando S, et al. (February 2013). "Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells". Nature. 494 (7435): 100–4. Bibcode:2013Natur.494..100A. doi:10.1038/nature11807. PMID 23302801. S2CID 205232231.
Shalom-Feuerstein R, Serror L, Aberdam E, Müller FJ, van Bokhoven H, Wiman KG, et al. (February 2013). "Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET". Proceedings of the National Academy of Sciences of the United States of America. 110 (6): 2152–6. Bibcode:2013PNAS..110.2152S. doi:10.1073/pnas.1201753109. PMC 3568301. PMID 23355677.
Park IH, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, et al. (September 2008). "Disease-specific induced pluripotent stem cells". Cell. 134 (5): 877–86. doi:10.1016/j.cell.2008.07.041. PMC 2633781. PMID 18691744.
Freedman BS, Lam AQ, Sundsbak JL, Iatrino R, Su X, Koon SJ, et al. (October 2013). "Reduced ciliary polycystin-2 in induced pluripotent stem cells from polycystic kidney disease patients with PKD1 mutations". Journal of the American Society of Nephrology. 24 (10): 1571–86. doi:10.1681/ASN.2012111089. PMC 3785271. PMID 24009235.
Dolmetsch R, Geschwind D (June 2011). "The human brain in a dish: the promise of iPSC-derived neurons". Cell. 145 (6): 831–4. doi:10.1016/j.cell.2011.05.034. PMC 3691069. PMID 21663789.
Grskovic M, Javaherian A, Strulovici B, Daley GQ (November 2011). "Induced pluripotent stem cells--opportunities for disease modeling and drug discovery". Nature Reviews. Drug Discovery. 10 (12): 915–29. doi:10.1038/nrd3577. PMID 22076509. S2CID 7945956.
Shi Y, Inoue H, Wu JC, Yamanaka S (February 2017). "Induced pluripotent stem cell technology: a decade of progress". Nat Rev Drug Discov. 16 (2): 115–30. doi:10.1038/nrd.2016.245. PMC 6416143. PMID 27980341.
Shinnawi R, Huber I, Maizels L, Shaheen N, Gepstein A, Arbel G, et al. (October 2015). "Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters". Stem Cell Reports. 5 (4): 582–96. doi:10.1016/j.stemcr.2015.08.009. PMC 4624957. PMID 26372632.
Shaheen N, Shiti A, Huber I, Shinnawi R, Arbel G, Gepstein A, et al. (June 2018). "Human Induced Pluripotent Stem Cell-Derived Cardiac Cell Sheets Expressing Genetically Encoded Voltage Indicator for Pharmacological and Arrhythmia Studies". Stem Cell Reports. 10 (6): 1879–1894. doi:10.1016/j.stemcr.2018.04.006. PMC 5989818. PMID 29754959.
Sharma, Arun; Burridge, Paul W.; McKeithan, Wesley L.; Serrano, Ricardo; Shukla, Praveen; Sayed, Nazish; Churko, Jared M.; Kitani, Tomoya; Wu, Haodi; Holmström, Alexandra; Matsa, Elena (15 February 2017). "High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells". Science Translational Medicine. 9 (377) eaaf2584. doi:10.1126/scitranslmed.aaf2584. ISSN 1946-6242. PMC 5409837. PMID 28202772.
McKeithan, Wesley L.; Savchenko, Alex; Yu, Michael S.; Cerignoli, Fabio; Bruyneel, Arne A. N.; Price, Jeffery H.; Colas, Alexandre R.; Miller, Evan W.; Cashman, John R.; Mercola, Mark (2017). "An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes". Frontiers in Physiology. 8 766. doi:10.3389/fphys.2017.00766. ISSN 1664-042X. PMC 5641590. PMID 29075196.
Serrano, Ricardo; Feyen, Dries A.M.; Bruyneel, Arne A.N.; Hnatiuk, Anna P.; Vu, Michelle M.; Amatya, Prashila L.; Perea-Gil, Isaac; Prado, Maricela; Seeger, Timon; Wu, Joseph C.; Karakikes, Ioannis; Mercola, Mark (January 2023). "A deep learning platform to assess drug proarrhythmia risk". Cell Stem Cell. 30 (1): 86–95.e4. doi:10.1016/j.stem.2022.12.002. PMC 9924077. PMID 36563695.
Takebe T, Sekine K, Enomura M, Koike H, Kimura M, Ogaeri T, et al. (July 2013). "Vascularized and functional human liver from an iPSC-derived organ bud transplant". Nature. 499 (7459): 481–4. Bibcode:2013Natur.499..481T. doi:10.1038/nature12271. PMID 23823721. S2CID 4423004.
Chen Y, Lüttmann FF, Schoger E, Schöler HR, Zelarayán LC, Kim KP, et al. (September 2021). "Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice". Science. 373 (6562): 1537–1540. Bibcode:2021Sci...373.1537C. doi:10.1126/science.abg5159. PMID 34554778. S2CID 237617229.
Park TS, Bhutto I, Zimmerlin L, Huo JS, Nagaria P, Miller D, et al. (January 2014). "Vascular progenitors from cord blood-derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature". Circulation. 129 (3): 359–72. doi:10.1161/CIRCULATIONAHA.113.003000. PMC 4090244. PMID 24163065.
Tang H, Sha H, Sun H, Wu X, Xie L, Wang P, et al. (October 2013). "Tracking induced pluripotent stem cells-derived neural stem cells in the central nervous system of rats and monkeys". Cellular Reprogramming. 15 (5): 435–42. doi:10.1089/cell.2012.0081. PMC 3787483. PMID 24020696.
Burridge PW, Matsa E, Shukla P, Lin ZC, Churko JM, Ebert AD, et al. (August 2014). "Chemically defined generation of human cardiomyocytes". Nature Methods. 11 (8): 855–60. doi:10.1038/nmeth.2999. PMC 4169698. PMID 24930130.
Feyen, Dries A. M.; McKeithan, Wesley L.; Bruyneel, Arne A. N.; Spiering, Sean; Hörmann, Larissa; Ulmer, Bärbel; Zhang, Hui; Briganti, Francesca; Schweizer, Michaela; Hegyi, Bence; Liao, Zhandi (21 July 2020). "Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes". Cell Reports. 32 (3) 107925. doi:10.1016/j.celrep.2020.107925. ISSN 2211-1247. PMC 7437654. PMID 32697997.
Willems E, Spiering S, Davidovics H, Lanier M, Xia Z, Dawson M, et al. (August 2011). "Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm". Circulation Research. 109 (4): 360–4. doi:10.1161/CIRCRESAHA.111.249540. PMC 3327303. PMID 21737789.
Yazawa M, Hsueh B, Jia X, Pasca AM, Bernstein JA, Hallmayer J, Dolmetsch RE (March 2011). "Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome". Nature. 471 (7337): 230–4. Bibcode:2011Natur.471..230Y. doi:10.1038/nature09855. PMC 3077925. PMID 21307850.
Itzhaki I, Maizels L, Huber I, Zwi-Dantsis L, Caspi O, Winterstern A, et al. (March 2011). "Modelling the long QT syndrome with induced pluripotent stem cells". Nature. 471 (7337): 225–9. Bibcode:2011Natur.471..225I. doi:10.1038/nature09747. PMID 21240260. S2CID 4384573.
Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, et al. (February 2017). "High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells". Science Translational Medicine. 9 (377) eaaf2584. doi:10.1126/scitranslmed.aaf2584. PMC 5409837. PMID 28202772.
McKeithan, Wesley L.; Feyen, Dries A. M.; Bruyneel, Arne A. N.; Okolotowicz, Karl J.; Ryan, Daniel A.; Sampson, Kevin J.; Potet, Franck; Savchenko, Alex; Gómez-Galeno, Jorge; Vu, Michelle; Serrano, Ricardo (5 November 2020). "Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity". Cell Stem Cell. 27 (5): 813–821.e6. doi:10.1016/j.stem.2020.08.003. ISSN 1875-9777. PMC 7655512. PMID 32931730.
Wei H, Wang C, Guo R, Takahashi K, Naruse K (December 2019). "Development of a model of ischemic heart disease using cardiomyocytes differentiated from human induced pluripotent stem cells". Biochemical and Biophysical Research Communications. 520 (3): 600–605. Bibcode:2019BBRC..520..600W. doi:10.1016/j.bbrc.2019.09.119. PMID 31623826.
Garber K (September 2015). "RIKEN suspends first clinical trial involving induced pluripotent stem cells". Nature Biotechnology. 33 (9): 890–1. doi:10.1038/nbt0915-890. PMID 26348942. S2CID 205271169.
Tobita M, Konomi K, Torashima Y, Kimura K, Taoka M, Kaminota M (June 2016). "Japan's challenges of translational regenerative medicine: Act on the safety of regenerative medicine". Regenerative Therapy. 4: 78–81. doi:10.1016/j.reth.2016.04.001. PMC 6581824. PMID 31245489.
Deinsberger J, Reisinger D, Weber B (11 September 2020). "Global trends in clinical trials involving pluripotent stem cells: a systematic multi-database analysis". npj Regenerative Medicine. 5 (1) 15. doi:10.1038/s41536-020-00100-4. PMC 7486930. PMID 32983575.
Koga K, Wang B, Kaneko S (2020). "Current status and future perspectives of HLA-edited induced pluripotent stem cells". Inflammation and Regeneration. 40 23. doi:10.1186/s41232-020-00132-9. PMC 7528263. PMID 33014207. This article incorporates text from this source, which is available under the CC BY 4.0 license.
Sarkar TJ, Quarta M, Mukherjee S, Colville A, Paine P, Doan L, et al. (March 2020). "Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells". Nature Communications. 11 (1) 1545. Bibcode:2020NatCo..11.1545S. doi:10.1038/s41467-020-15174-3. PMC 7093390. PMID 32210226.
Asadi-Sarabi, Pedram; Rismani, Elham; Shabanpouremam, Mahshid; Hendi, Zahra; Nikoubin, Behnaz; Zarrabi, Ali; Vosough, Massoud (2025). "Hypoimmunogenic pluripotent stem cells: A game-changer in cell-based regenerative medicine". International Immunopharmacology. 162 115134: 115–134. doi:10.1016/j.intimp.2025.115134. PMID 40580745.

ncbi.nlm.nih.gov

Mahla RS (2016). "Stem Cells Applications in Regenerative Medicine and Disease Therapeutics". International Journal of Cell Biology. 2016 6940283. doi:10.1155/2016/6940283. PMC 4969512. PMID 27516776.
Hockemeyer D, Jaenisch R (May 2016). "Induced Pluripotent Stem Cells Meet Genome Editing". Cell Stem Cell. 18 (5): 573–86. doi:10.1016/j.stem.2016.04.013. PMC 4871596. PMID 27152442.
Eguizabal C, Aran B, Chuva de Sousa Lopes SM, Geens M, Heindryckx B, Panula S, Popovic M, Vassena R, Veiga A (2019). "Two decades of embryonic stem cells: a historical overview". Human Reproduction Open. 2019 (1) hoy024. doi:10.1093/hropen/hoy024. PMC 6396646. PMID 30895264.
Guo XL, Chen JS (2015). "Research on induced pluripotent stem cells and the application in ocular tissues". International Journal of Ophthalmology. 8 (4): 818–25. doi:10.3980/j.issn.2222-3959.2015.04.31. PMC 4539634. PMID 26309885.
Thornton, Christopher D.; Fielding, Stuart; Karbowniczek, Kinga; Roig-Merino, Alicia; Burrows, Alysha E.; FitzPatrick, Lorna M.; Sharaireh, Aseel; Tite, John P.; Mole, Sara E.; Harbottle, Richard P.; Caproni, Lisa J.; McKay, Tristan R. (10 December 2021). "Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors". Molecular Therapy - Methods & Clinical Development. 23: 348–358. doi:10.1016/j.omtm.2021.09.018. ISSN 2329-0501. PMC 8546411. PMID 34729381.
Maherali N, Ahfeldt T, Rigamonti A, Utikal J, Cowan C, Hochedlinger K (September 2008). "A high-efficiency system for the generation and study of human induced pluripotent stem cells". Cell Stem Cell. 3 (3): 340–5. doi:10.1016/j.stem.2008.08.003. PMC 3987901. PMID 18786420.
Staerk J, Dawlaty MM, Gao Q, Maetzel D, Hanna J, Sommer CA, et al. (July 2010). "Reprogramming of human peripheral blood cells to induced pluripotent stem cells". Cell Stem Cell. 7 (1): 20–4. doi:10.1016/j.stem.2010.06.002. PMC 2917234. PMID 20621045.
Loh YH, Hartung O, Li H, Guo C, Sahalie JM, Manos PD, et al. (July 2010). "Reprogramming of T cells from human peripheral blood". Cell Stem Cell. 7 (1): 15–9. doi:10.1016/j.stem.2010.06.004. PMC 2913590. PMID 20621044.
Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, Tan KY, et al. (August 2010). "Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells". Nature Biotechnology. 28 (8): 848–55. doi:10.1038/nbt.1667. PMC 3148605. PMID 20644536.
Velychko S, Adachi K, Kim KP, Hou Y, MacCarthy CM, Wu G, Schöler HR (December 2019). "Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs". Cell Stem Cell. 25 (6): 737–753.e4. doi:10.1016/j.stem.2019.10.002. PMC 6900749. PMID 31708402.
Selvaraj V, Plane JM, Williams AJ, Deng W (April 2010). "Switching cell fate: the remarkable rise of induced pluripotent stem cells and lineage reprogramming technologies". Trends in Biotechnology. 28 (4): 214–23. doi:10.1016/j.tibtech.2010.01.002. PMC 2843790. PMID 20149468.
Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K (November 2008). "Induced pluripotent stem cells generated without viral integration". Science. 322 (5903): 945–9. Bibcode:2008Sci...322..945S. doi:10.1126/science.1162494. PMC 3987909. PMID 18818365.
Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hämäläinen R, et al. (April 2009). "piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells". Nature. 458 (7239): 766–70. Bibcode:2009Natur.458..766W. doi:10.1038/nature07863. PMC 3758996. PMID 19252478.
Marión RM, Strati K, Li H, Murga M, Blanco R, Ortega S, et al. (August 2009). "A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity". Nature. 460 (7259): 1149–53. Bibcode:2009Natur.460.1149M. doi:10.1038/nature08287. PMC 3624089. PMID 19668189.
Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, Chen AE, Melton DA (July 2008). "Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds". Nature Biotechnology. 26 (7): 795–7. doi:10.1038/nbt1418. PMC 6334647. PMID 18568017.
Lin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, et al. (November 2009). "A chemical platform for improved induction of human iPSCs". Nature Methods. 6 (11): 805–8. doi:10.1038/nmeth.1393. PMC 3724527. PMID 19838168.
Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, et al. (May 2009). "Generation of induced pluripotent stem cells using recombinant proteins". Cell Stem Cell. 4 (5): 381–4. doi:10.1016/j.stem.2009.04.005. PMC 10182564. PMID 19398399.
Judson RL, Babiarz JE, Venere M, Blelloch R (May 2009). "Embryonic stem cell-specific microRNAs promote induced pluripotency". Nature Biotechnology. 27 (5): 459–61. doi:10.1038/nbt.1535. PMC 2743930. PMID 19363475.
Guenther MG, Frampton GM, Soldner F, Hockemeyer D, Mitalipova M, Jaenisch R, Young RA (August 2010). "Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells". Cell Stem Cell. 7 (2): 249–57. doi:10.1016/j.stem.2010.06.015. PMC 3010384. PMID 20682450.
Lister R, Pelizzola M, Kida YS, Hawkins RD, Nery JR, Hon G, et al. (March 2011). "Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells". Nature. 471 (7336): 68–73. Bibcode:2011Natur.471...68L. doi:10.1038/nature09798. PMC 3100360. PMID 21289626.
Knoepfler PS (May 2009). "Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine". Stem Cells. 27 (5): 1050–6. doi:10.1002/stem.37. PMC 2733374. PMID 19415771.
Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, et al. (October 2011). "Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice". Proceedings of the National Academy of Sciences of the United States of America. 108 (40): 16825–30. Bibcode:2011PNAS..10816825N. doi:10.1073/pnas.1108077108. PMC 3189018. PMID 21949375.
Nori S, Okada Y, Nishimura S, Sasaki T, Itakura G, Kobayashi Y, et al. (March 2015). "Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transition". Stem Cell Reports. 4 (3): 360–73. doi:10.1016/j.stemcr.2015.01.006. PMC 4375796. PMID 25684226.
Gutierrez-Aranda I, Ramos-Mejia V, Bueno C, Munoz-Lopez M, Real PJ, Mácia A, et al. (September 2010). "Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection". Stem Cells. 28 (9): 1568–70. doi:10.1002/stem.471. PMC 2996086. PMID 20641038.
Shalom-Feuerstein R, Serror L, Aberdam E, Müller FJ, van Bokhoven H, Wiman KG, et al. (February 2013). "Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET". Proceedings of the National Academy of Sciences of the United States of America. 110 (6): 2152–6. Bibcode:2013PNAS..110.2152S. doi:10.1073/pnas.1201753109. PMC 3568301. PMID 23355677.
Park IH, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, et al. (September 2008). "Disease-specific induced pluripotent stem cells". Cell. 134 (5): 877–86. doi:10.1016/j.cell.2008.07.041. PMC 2633781. PMID 18691744.
Freedman BS, Lam AQ, Sundsbak JL, Iatrino R, Su X, Koon SJ, et al. (October 2013). "Reduced ciliary polycystin-2 in induced pluripotent stem cells from polycystic kidney disease patients with PKD1 mutations". Journal of the American Society of Nephrology. 24 (10): 1571–86. doi:10.1681/ASN.2012111089. PMC 3785271. PMID 24009235.
Dolmetsch R, Geschwind D (June 2011). "The human brain in a dish: the promise of iPSC-derived neurons". Cell. 145 (6): 831–4. doi:10.1016/j.cell.2011.05.034. PMC 3691069. PMID 21663789.
Shi Y, Inoue H, Wu JC, Yamanaka S (February 2017). "Induced pluripotent stem cell technology: a decade of progress". Nat Rev Drug Discov. 16 (2): 115–30. doi:10.1038/nrd.2016.245. PMC 6416143. PMID 27980341.
Shinnawi R, Huber I, Maizels L, Shaheen N, Gepstein A, Arbel G, et al. (October 2015). "Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters". Stem Cell Reports. 5 (4): 582–96. doi:10.1016/j.stemcr.2015.08.009. PMC 4624957. PMID 26372632.
Shaheen N, Shiti A, Huber I, Shinnawi R, Arbel G, Gepstein A, et al. (June 2018). "Human Induced Pluripotent Stem Cell-Derived Cardiac Cell Sheets Expressing Genetically Encoded Voltage Indicator for Pharmacological and Arrhythmia Studies". Stem Cell Reports. 10 (6): 1879–1894. doi:10.1016/j.stemcr.2018.04.006. PMC 5989818. PMID 29754959.
Sharma, Arun; Burridge, Paul W.; McKeithan, Wesley L.; Serrano, Ricardo; Shukla, Praveen; Sayed, Nazish; Churko, Jared M.; Kitani, Tomoya; Wu, Haodi; Holmström, Alexandra; Matsa, Elena (15 February 2017). "High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells". Science Translational Medicine. 9 (377) eaaf2584. doi:10.1126/scitranslmed.aaf2584. ISSN 1946-6242. PMC 5409837. PMID 28202772.
McKeithan, Wesley L.; Savchenko, Alex; Yu, Michael S.; Cerignoli, Fabio; Bruyneel, Arne A. N.; Price, Jeffery H.; Colas, Alexandre R.; Miller, Evan W.; Cashman, John R.; Mercola, Mark (2017). "An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes". Frontiers in Physiology. 8 766. doi:10.3389/fphys.2017.00766. ISSN 1664-042X. PMC 5641590. PMID 29075196.
Serrano, Ricardo; Feyen, Dries A.M.; Bruyneel, Arne A.N.; Hnatiuk, Anna P.; Vu, Michelle M.; Amatya, Prashila L.; Perea-Gil, Isaac; Prado, Maricela; Seeger, Timon; Wu, Joseph C.; Karakikes, Ioannis; Mercola, Mark (January 2023). "A deep learning platform to assess drug proarrhythmia risk". Cell Stem Cell. 30 (1): 86–95.e4. doi:10.1016/j.stem.2022.12.002. PMC 9924077. PMID 36563695.
Park TS, Bhutto I, Zimmerlin L, Huo JS, Nagaria P, Miller D, et al. (January 2014). "Vascular progenitors from cord blood-derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature". Circulation. 129 (3): 359–72. doi:10.1161/CIRCULATIONAHA.113.003000. PMC 4090244. PMID 24163065.
Tang H, Sha H, Sun H, Wu X, Xie L, Wang P, et al. (October 2013). "Tracking induced pluripotent stem cells-derived neural stem cells in the central nervous system of rats and monkeys". Cellular Reprogramming. 15 (5): 435–42. doi:10.1089/cell.2012.0081. PMC 3787483. PMID 24020696.
Burridge PW, Matsa E, Shukla P, Lin ZC, Churko JM, Ebert AD, et al. (August 2014). "Chemically defined generation of human cardiomyocytes". Nature Methods. 11 (8): 855–60. doi:10.1038/nmeth.2999. PMC 4169698. PMID 24930130.
Feyen, Dries A. M.; McKeithan, Wesley L.; Bruyneel, Arne A. N.; Spiering, Sean; Hörmann, Larissa; Ulmer, Bärbel; Zhang, Hui; Briganti, Francesca; Schweizer, Michaela; Hegyi, Bence; Liao, Zhandi (21 July 2020). "Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes". Cell Reports. 32 (3) 107925. doi:10.1016/j.celrep.2020.107925. ISSN 2211-1247. PMC 7437654. PMID 32697997.
Willems E, Spiering S, Davidovics H, Lanier M, Xia Z, Dawson M, et al. (August 2011). "Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm". Circulation Research. 109 (4): 360–4. doi:10.1161/CIRCRESAHA.111.249540. PMC 3327303. PMID 21737789.
Yazawa M, Hsueh B, Jia X, Pasca AM, Bernstein JA, Hallmayer J, Dolmetsch RE (March 2011). "Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome". Nature. 471 (7337): 230–4. Bibcode:2011Natur.471..230Y. doi:10.1038/nature09855. PMC 3077925. PMID 21307850.
Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, et al. (February 2017). "High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells". Science Translational Medicine. 9 (377) eaaf2584. doi:10.1126/scitranslmed.aaf2584. PMC 5409837. PMID 28202772.
McKeithan, Wesley L.; Feyen, Dries A. M.; Bruyneel, Arne A. N.; Okolotowicz, Karl J.; Ryan, Daniel A.; Sampson, Kevin J.; Potet, Franck; Savchenko, Alex; Gómez-Galeno, Jorge; Vu, Michelle; Serrano, Ricardo (5 November 2020). "Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity". Cell Stem Cell. 27 (5): 813–821.e6. doi:10.1016/j.stem.2020.08.003. ISSN 1875-9777. PMC 7655512. PMID 32931730.
Tobita M, Konomi K, Torashima Y, Kimura K, Taoka M, Kaminota M (June 2016). "Japan's challenges of translational regenerative medicine: Act on the safety of regenerative medicine". Regenerative Therapy. 4: 78–81. doi:10.1016/j.reth.2016.04.001. PMC 6581824. PMID 31245489.
Deinsberger J, Reisinger D, Weber B (11 September 2020). "Global trends in clinical trials involving pluripotent stem cells: a systematic multi-database analysis". npj Regenerative Medicine. 5 (1) 15. doi:10.1038/s41536-020-00100-4. PMC 7486930. PMID 32983575.
Koga K, Wang B, Kaneko S (2020). "Current status and future perspectives of HLA-edited induced pluripotent stem cells". Inflammation and Regeneration. 40 23. doi:10.1186/s41232-020-00132-9. PMC 7528263. PMID 33014207. This article incorporates text from this source, which is available under the CC BY 4.0 license.
Sarkar TJ, Quarta M, Mukherjee S, Colville A, Paine P, Doan L, et al. (March 2020). "Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells". Nature Communications. 11 (1) 1545. Bibcode:2020NatCo..11.1545S. doi:10.1038/s41467-020-15174-3. PMC 7093390. PMID 32210226.

nikkei.com (Global: 211^th place; English: 915^th place)

"iPSから心筋細胞製造タカラバイオとベンチャー". 日本経済新聞電子版 (in Japanese). 24 June 2014. Retrieved 8 November 2019.
"iPSで心臓治療了承高難度の再生医療へ一歩". 日本経済新聞電子版 (in Japanese). 16 May 2018. Retrieved 8 November 2019.

nobelprize.org (Global: 301^st place; English: 478^th place)

"The Nobel Prize in Physiology or Medicine – 2012 Press Release". Nobel Media AB. 8 October 2012.

psu.edu (Global: 207^th place; English: 136^th place)

citeseerx.ist.psu.edu

Zhao T, Zhang ZN, Rong Z, Xu Y (May 2011). "Immunogenicity of induced pluripotent stem cells". Nature. 474 (7350): 212–5. CiteSeerX 10.1.1.864.8029. doi:10.1038/nature10135. PMID 21572395. S2CID 4416964.

reuters.com (Global: 49^th place; English: 47^th place)

Lies E (4 June 2014). "Japan researcher agrees to withdraw disputed stem cell paper". Reuters. Retrieved 4 June 2014.

riken.jp (Global: low place; English: low place)

cdb.riken.jp

Riken Center for Developmental Biology. "Information on p=roposed pilot study of the safety and feasibility of transplantation of autologous hiPSC-derived retinal pigment epithelium (RPE) cell sheets in patients with neovascular age-related macular degeneration". Research. Archived from the original on 26 June 2013. Retrieved 23 July 2013.
"First donor iPSC-derived RPE cell transplantation in AMD patient". RIKEN Center for Developmental Biology. 4 April 2017. Archived from the original on 6 September 2017. Retrieved 6 September 2017.

riken.jp

Press Release (1 April 2014). "Report on STAP Cell Research Paper Investigation". RIKEN. Retrieved 2 June 2014.

sbaminbeta.blogspot.com (Global: low place; English: low place)

"Generations of iPSCs and related references". Archived from the original on 30 June 2018. Retrieved 5 November 2007.

sciam.com (Global: 6,119^th place; English: 6,509^th place)

Swaminathan N (30 November 2007). "Stem Cells – This Time Without the Cancer". Scientific American News. Retrieved 11 December 2007.

sciencedaily.com (Global: 993^rd place; English: 920^th place)

"Major Step In Making Better Stem Cells From Adult Tissue". Science Daily. 19 October 2009. Retrieved 30 September 2013.

sciencedirect.com (Global: 149^th place; English: 178^th place)

Asadi-Sarabi, Pedram; Rismani, Elham; Shabanpouremam, Mahshid; Hendi, Zahra; Nikoubin, Behnaz; Zarrabi, Ali; Vosough, Massoud (2025). "Hypoimmunogenic pluripotent stem cells: A game-changer in cell-based regenerative medicine". International Immunopharmacology. 162 115134: 115–134. doi:10.1016/j.intimp.2025.115134. PMID 40580745.

semanticscholar.org (Global: 11^th place; English: 8^th place)

api.semanticscholar.org

Klimanskaya I, Chung Y, Becker S, Lu SJ, Lanza R (November 2006). "Human embryonic stem cell lines derived from single blastomeres". Nature. 444 (7118): 481–5. Bibcode:2006Natur.444..481K. doi:10.1038/nature05142. PMID 16929302. S2CID 84792371.
Okita K, Ichisaka T, Yamanaka S (July 2007). "Generation of germline-competent induced pluripotent stem cells". Nature. 448 (7151): 313–7. Bibcode:2007Natur.448..313O. doi:10.1038/nature05934. PMID 17554338. S2CID 459050.
Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, et al. (July 2007). "In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state". Nature. 448 (7151): 318–24. Bibcode:2007Natur.448..318W. doi:10.1038/nature05944. PMID 17554336. S2CID 4377572.
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, et al. (December 2007). "Induced pluripotent stem cell lines derived from human somatic cells". Science. 318 (5858): 1917–20. Bibcode:2007Sci...318.1917Y. doi:10.1126/science.1151526. PMID 18029452. S2CID 86129154.
Aasen T, Raya A, Barrero MJ, Garreta E, Consiglio A, Gonzalez F, et al. (November 2008). "Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes". Nature Biotechnology. 26 (11): 1276–84. doi:10.1038/nbt.1503. PMID 18931654. S2CID 205274019.
Zhou T, Benda C, Dunzinger S, Huang Y, Ho JC, Yang J, et al. (December 2012). "Generation of human induced pluripotent stem cells from urine samples". Nature Protocols. 7 (12): 2080–9. doi:10.1038/nprot.2012.115. PMID 23138349. S2CID 205465442.
Ali PS, Ghoshdastider U, Hoffmann J, Brutschy B, Filipek S (November 2012). "Recognition of the let-7g miRNA precursor by human Lin28B". FEBS Letters. 586 (22): 3986–90. Bibcode:2012FEBSL.586.3986S. doi:10.1016/j.febslet.2012.09.034. PMID 23063642. S2CID 28899778.
Maekawa M, Yamaguchi K, Nakamura T, Shibukawa R, Kodanaka I, Ichisaka T, et al. (June 2011). "Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1". Nature. 474 (7350): 225–9. doi:10.1038/nature10106. hdl:2433/141930. PMID 21654807. S2CID 4428172.
Luo M, Ling T, Xie W, Sun H, Zhou Y, Zhu Q, et al. (July 2013). "NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells". Stem Cells. 31 (7): 1278–86. doi:10.1002/stem.1374. hdl:10397/18487. PMID 23533168. S2CID 206512562.
Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, et al. (October 2013). "Deterministic direct reprogramming of somatic cells to pluripotency". Nature. 502 (7469): 65–70. Bibcode:2013Natur.502...65R. doi:10.1038/nature12587. PMID 24048479. S2CID 4386833.
Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S (November 2008). "Generation of mouse induced pluripotent stem cells without viral vectors". Science. 322 (5903): 949–53. Bibcode:2008Sci...322..949O. doi:10.1126/science.1164270. PMID 18845712. S2CID 23735743.
Zhao XY, Li W, Lv Z, Liu L, Tong M, Hai T, et al. (September 2009). "iPS cells produce viable mice through tetraploid complementation". Nature. 461 (7260): 86–90. Bibcode:2009Natur.461...86Z. doi:10.1038/nature08267. PMID 19672241. S2CID 205217762.
Cyranoski D (18 July 2013). "Stem cells reprogrammed using chemicals alone". Nature News. doi:10.1038/nature.2013.13416. S2CID 88247014. Retrieved 22 July 2013.
Hou P, Li Y, Zhang X, Liu C, Guan J, Li H, et al. (August 2013). "Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds". Science. 341 (6146): 651–4. Bibcode:2013Sci...341..651H. doi:10.1126/science.1239278. PMID 23868920. S2CID 45685692.
Zhou W, Freed CR (November 2009). "Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells". Stem Cells. 27 (11): 2667–74. doi:10.1002/stem.201. PMID 19697349. S2CID 41418742.
Boland MJ, Hazen JL, Nazor KL, Rodriguez AR, Gifford W, Martin G, et al. (September 2009). "Adult mice generated from induced pluripotent stem cells". Nature. 461 (7260): 91–4. Bibcode:2009Natur.461...91B. doi:10.1038/nature08310. PMID 19672243. S2CID 4423755.
Aoi T, Yae K, Nakagawa M, Ichisaka T, Okita K, Takahashi K, et al. (August 2008). "Generation of pluripotent stem cells from adult mouse liver and stomach cells". Science. 321 (5889): 699–702. Bibcode:2008Sci...321..699A. doi:10.1126/science.1154884. hdl:2433/124215. PMID 18276851. S2CID 52869734.
Zhao T, Zhang ZN, Rong Z, Xu Y (May 2011). "Immunogenicity of induced pluripotent stem cells". Nature. 474 (7350): 212–5. CiteSeerX 10.1.1.864.8029. doi:10.1038/nature10135. PMID 21572395. S2CID 4416964.
Araki R, Uda M, Hoki Y, Sunayama M, Nakamura M, Ando S, et al. (February 2013). "Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells". Nature. 494 (7435): 100–4. Bibcode:2013Natur.494..100A. doi:10.1038/nature11807. PMID 23302801. S2CID 205232231.
Grskovic M, Javaherian A, Strulovici B, Daley GQ (November 2011). "Induced pluripotent stem cells--opportunities for disease modeling and drug discovery". Nature Reviews. Drug Discovery. 10 (12): 915–29. doi:10.1038/nrd3577. PMID 22076509. S2CID 7945956.
Baker M (3 July 2013). "Miniature human liver grown in mice". Nature. doi:10.1038/nature.2013.13324. S2CID 87064973. Retrieved 19 July 2013.
Takebe T, Sekine K, Enomura M, Koike H, Kimura M, Ogaeri T, et al. (July 2013). "Vascularized and functional human liver from an iPSC-derived organ bud transplant". Nature. 499 (7459): 481–4. Bibcode:2013Natur.499..481T. doi:10.1038/nature12271. PMID 23823721. S2CID 4423004.
Chen Y, Lüttmann FF, Schoger E, Schöler HR, Zelarayán LC, Kim KP, et al. (September 2021). "Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice". Science. 373 (6562): 1537–1540. Bibcode:2021Sci...373.1537C. doi:10.1126/science.abg5159. PMID 34554778. S2CID 237617229.
Itzhaki I, Maizels L, Huber I, Zwi-Dantsis L, Caspi O, Winterstern A, et al. (March 2011). "Modelling the long QT syndrome with induced pluripotent stem cells". Nature. 471 (7337): 225–9. Bibcode:2011Natur.471..225I. doi:10.1038/nature09747. PMID 21240260. S2CID 4384573.
Garber K (September 2015). "RIKEN suspends first clinical trial involving induced pluripotent stem cells". Nature Biotechnology. 33 (9): 890–1. doi:10.1038/nbt0915-890. PMID 26348942. S2CID 205271169.

sponichi.co.jp (Global: 103^rd place; English: 3,583^rd place)

"万能なiPS細胞「iPodのように普及してほしい」". スポーツニッポン. 9 October 2012. Retrieved 14 October 2012.

the-scientist.com (Global: 7,827^th place; English: 5,905^th place)

Tracy Vence for the Scientist. March 11, 2014 Call for STAP Retractions

web.archive.org (Global: 1^st place; English: 1^st place)

"「i」PSなぜ小文字？山中さんってどんな人？". 朝日新聞. 8 October 2012. Archived from the original on 21 November 2012. Retrieved 27 April 2013.
"Generations of iPSCs and related references". Archived from the original on 30 June 2018. Retrieved 5 November 2007.
"ｉＰＳ細胞の心筋シート移植、臨床研究を国が大筋了承：朝日新聞デジタル". 朝日新聞デジタル (in Japanese). 16 May 2018. Archived from the original on 8 November 2019. Retrieved 8 November 2019.
Riken Center for Developmental Biology. "Information on p=roposed pilot study of the safety and feasibility of transplantation of autologous hiPSC-derived retinal pigment epithelium (RPE) cell sheets in patients with neovascular age-related macular degeneration". Research. Archived from the original on 26 June 2013. Retrieved 23 July 2013.
"First donor iPSC-derived RPE cell transplantation in AMD patient". RIKEN Center for Developmental Biology. 4 April 2017. Archived from the original on 6 September 2017. Retrieved 6 September 2017.
"First serious adverse reaction to iPS-derived retinal cell transplant reported". The Japan Times Online. 17 January 2018. Archived from the original on 27 January 2018. Retrieved 27 January 2018.

worldcat.org (Global: 5^th place; English: 5^th place)

search.worldcat.org

Thornton, Christopher D.; Fielding, Stuart; Karbowniczek, Kinga; Roig-Merino, Alicia; Burrows, Alysha E.; FitzPatrick, Lorna M.; Sharaireh, Aseel; Tite, John P.; Mole, Sara E.; Harbottle, Richard P.; Caproni, Lisa J.; McKay, Tristan R. (10 December 2021). "Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors". Molecular Therapy - Methods & Clinical Development. 23: 348–358. doi:10.1016/j.omtm.2021.09.018. ISSN 2329-0501. PMC 8546411. PMID 34729381.
Sharma, Arun; Burridge, Paul W.; McKeithan, Wesley L.; Serrano, Ricardo; Shukla, Praveen; Sayed, Nazish; Churko, Jared M.; Kitani, Tomoya; Wu, Haodi; Holmström, Alexandra; Matsa, Elena (15 February 2017). "High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells". Science Translational Medicine. 9 (377) eaaf2584. doi:10.1126/scitranslmed.aaf2584. ISSN 1946-6242. PMC 5409837. PMID 28202772.
McKeithan, Wesley L.; Savchenko, Alex; Yu, Michael S.; Cerignoli, Fabio; Bruyneel, Arne A. N.; Price, Jeffery H.; Colas, Alexandre R.; Miller, Evan W.; Cashman, John R.; Mercola, Mark (2017). "An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes". Frontiers in Physiology. 8 766. doi:10.3389/fphys.2017.00766. ISSN 1664-042X. PMC 5641590. PMID 29075196.
Feyen, Dries A. M.; McKeithan, Wesley L.; Bruyneel, Arne A. N.; Spiering, Sean; Hörmann, Larissa; Ulmer, Bärbel; Zhang, Hui; Briganti, Francesca; Schweizer, Michaela; Hegyi, Bence; Liao, Zhandi (21 July 2020). "Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes". Cell Reports. 32 (3) 107925. doi:10.1016/j.celrep.2020.107925. ISSN 2211-1247. PMC 7437654. PMID 32697997.
McKeithan, Wesley L.; Feyen, Dries A. M.; Bruyneel, Arne A. N.; Okolotowicz, Karl J.; Ryan, Daniel A.; Sampson, Kevin J.; Potet, Franck; Savchenko, Alex; Gómez-Galeno, Jorge; Vu, Michelle; Serrano, Ricardo (5 November 2020). "Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity". Cell Stem Cell. 27 (5): 813–821.e6. doi:10.1016/j.stem.2020.08.003. ISSN 1875-9777. PMC 7655512. PMID 32931730.

Induced pluripotent stem cell (English Wikipedia)

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