Kevin Struhl (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Kevin Struhl" in English language version.

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Hirsch, Heather A; Iliopoulos, Dimitrios; Tsichlis, Philip N; Struhl, Kevin (2009-10-01). "Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission". Cancer Research. 69 (19): 7507–7511. doi:10.1158/0008-5472.CAN-09-2994. PMC 2756324. PMID 19752085.
Iliopoulos, Dimitrios; Hirsch, Heather A; Struhl, Kevin (2011-04-29). "Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types". Cancer Research. 71 (9): 3196–3201. doi:10.1158/0008-5472.CAN-10-3471. PMC 3085572. PMID 21415163.

amacad.org

"American Academy of Arts & Sciences". American Academy of Arts & Sciences. 12 July 2023.

annualreviews.org

Struhl, Kevin (1995). "Yeast Transcriptional Regulatory Mechanisms". Annual Review of Genetics. 29: 651–674. doi:10.1146/annurev.ge.29.120195.003251. PMID 8825489.

asbmb.org

Chandler, Courtney (2022-12-02). "'Independent agents' no more". American Society for Biochemistry and Molecular Biology.

cell.com

Cormack, BP; Struhl, K (1992-05-15). "The TATA-binding protein is required for transcription by all three nuclear RNA polymerases in yeast cells". Cell. 69 (4): 685–696. doi:10.1016/0092-8674(92)90232-2. PMID 1586947. S2CID 7419671.

cshlp.org

genesdev.cshlp.org

Ng, Huck Hui; Feng, Qin; Wang, Hengbin; Erdjument-Bromage, Hediye; Tempst, Paul; Zhang, Yi; Struhl, Kevin (2002). "Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association". Genes & Development. 16 (12): 1518–1527. doi:10.1101/gad.1001502. PMC 186335. PMID 12080090.
Miotto, Benoit; Struhl, Kevin (2008). "HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1". Genes & Development. 22 (19): 2633–2638. doi:10.1101/gad.1674108. PMC 2559906. PMID 18832067.

doi.org

doi.org

Struhl, Kevin (1995). "Yeast Transcriptional Regulatory Mechanisms". Annual Review of Genetics. 29: 651–674. doi:10.1146/annurev.ge.29.120195.003251. PMID 8825489.
Struhl, K; Davis, RW (1977-12-01). "Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3)". PNAS. 74 (12): 5255–5259. Bibcode:1977PNAS...74.5255S. doi:10.1073/pnas.74.12.5255. PMC 431671. PMID 341150.
Struhl, K; Cameron, JR; Davis, RW (1976-05-01). "Functional genetic expression of eukaryotic DNA in Escherichia coli". PNAS. 73 (5): 1471–1475. Bibcode:1976PNAS...73.1471S. doi:10.1073/pnas.73.5.1471. PMC 430318. PMID 775490.
Struhl, K; Stinchcomb, DT; Scherer, S; Davis, RW (1979-03-01). "High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules". PNAS. 76 (3): 1035–1039. Bibcode:1979PNAS...76.1035S. doi:10.1073/pnas.76.3.1035. PMC 383183. PMID 375221.
Stinchcomb, DT; Struhl, K; Davis, RW (1979-11-01). "Isolation and characterization of a yeast chromosomal replicator". Nature. 282 (5734): 39–43. Bibcode:1979Natur.282...39S. doi:10.1038/282039a0. PMID 388229. S2CID 4326901.
Struhl, Kevin (1981-07-01). "Deletion mapping a eukaryotic promoter". PNAS. 78 (7): 4461–4465. Bibcode:1981PNAS...78.4461S. doi:10.1073/pnas.78.7.4461. PMC 319811. PMID 7027262.
Struhl, Kevin (1982-11-18). "Regulatory sites for his3 expression in yeast". Nature. 300 (5889): 285–286. doi:10.1038/300284a0. PMID 6755264. S2CID 4308484.
Struhl, Kevin (1985-12-01). "Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast". PNAS. 82 (24): 8419–8423. Bibcode:1985PNAS...82.8419S. doi:10.1073/pnas.82.24.8419. PMC 390927. PMID 3909145.
Chen, W; Struhl, K (1988-04-01). "Saturation mutagenesis of a yeast his3 TATA element: genetic evidence for a specific TATA-binding protein". PNAS. 85 (8): 2691–2695. Bibcode:1988PNAS...85.2691C. doi:10.1073/pnas.85.8.2691. PMC 280064. PMID 3282236.
Struhl, Kevin (1986-05-29). "Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms". Molecular and Cellular Biology. 6 (11): 3847–3853. doi:10.1128/mcb.6.11.3847-3853.1986. PMC 367147. PMID 3540601.
Chen, W; Struhl, K (1985-12-01). "Yeast mRNA initiation sites are determined primarily by specific sequences, not by the distance from the TATA element". The EMBO Journal. 4 (12): 3273–3280. doi:10.1002/j.1460-2075.1985.tb04077.x. PMC 554654. PMID 3912167.
Struhl, Kevin (1985-10-01). "Negative control at a distance mediates catabolite repression in yeast". Nature. 317 (6040): 822–824. Bibcode:1985Natur.317..822S. doi:10.1038/317822a0. PMID 3903516. S2CID 2404872.
Hope, IA; Struhl, K (November 1988). "GCN4 protein, synthesized in vitro, binds to HIS3 regulatory sequences: implications for the general control of amino acid biosynthetic genes in yeast". Cell. 43 (1): 177–188. doi:10.1016/0092-8674(85)90022-4. PMID 3907851. S2CID 22627291.
Oliphant, AR; Brandl, CJ; Struhl, K (1989-07-01). "Defining sequence specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: Analysis of the yeast GCN4 protein". Molecular and Cellular Biology. 9 (7): 2944–2949. doi:10.1128/mcb.9.7.2944-2949.1989. PMC 362762. PMID 2674675.
Hope, IA; Struhl, K (1987-09-01). "GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA". The EMBO Journal. 6 (9): 2781–2784. doi:10.1002/j.1460-2075.1987.tb02573.x. PMC 553703. PMID 3678204.
Sellers, JW; Struhl, K (1989-09-07). "Changing fos oncoprotein to a DNA-binding protein with GCN4 dimerization specificity by swapping "leucine zippers"". Nature. 341 (6237): 74–76. doi:10.1038/341074a0. PMID 2505087. S2CID 4253004.
Ellenberger, Thomas E; Brandl, Christopher J; Struhl, Kevin; Harrison, Stephen C (1992-12-24). "The GCN4 basic-region-leucine zipper binds DNA as a dimer of uninterrupted a-helices: crystal structure of the protein-DNA complex". Cell. 71 (7): 1223–1237. doi:10.1016/S0092-8674(05)80070-4. PMID 1473154. S2CID 13548424.
Weiss, Michael A; Ellenberger, Thomas; Wobbe, C Richard; Lee, Jonathan P; Harrison, Stephen C; Struhl, Kevin (1990). "Folding transition in the DNA-binding domain of GCN4 on specific binding to DNA". Nature. 347 (6293): 575–578. Bibcode:1990Natur.347..575W. doi:10.1038/347575a0. PMID 2145515. S2CID 4366430.
Hope, IA; Struhl, K (1986-09-12). "Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast". Cell. 46 (6): 885–894. doi:10.1016/0092-8674(86)90070-X. PMID 3530496. S2CID 40730692.
Hope, IA; Mahadevan, S; Struhl, K (1988-06-16). "Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein". Nature. 333 (6174): 635–640. Bibcode:1988Natur.333..635H. doi:10.1038/333635a0. PMID 3287180. S2CID 2635634.
Struhl, Kevin (1987-09-11). "The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator are functionally homologous". Cell. 50 (6): 841–846. doi:10.1016/0092-8674(87)90511-3. PMID 3040261. S2CID 29588878.
Struhl, Kevin (1988-04-14). "The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast". Nature. 332 (6165): 649–650. Bibcode:1988Natur.332..649S. doi:10.1038/332649a0. PMID 3128739. S2CID 4350206.
Chen, W; Tabor, S; Struhl, K (1987-09-25). "Distinguishing between mechanisms of eukaryotic transcriptional activation with bacteriophage T7 RNA polymerase". Cell. 266 (5183): 280–282. doi:10.1126/science.7939664. PMID 7939664.
Klein, C; Struhl, K (1994-10-19). "Increased recruitment of TATA-binding protein to the promoter by transcriptional activation domains in vivo". Science. 266 (5183): 280–282. doi:10.1126/science.7939664. PMID 7939664.
Keaveney, M; Struhl, K (May 1998). "Activator-mediated recruitment of the RNA polymerase II machinery is the predominant mechanism for transcriptional activation in yeast". Molecular Cell. 1 (6): 917–924. doi:10.1016/S1097-2765(00)80091-X. PMID 9660975.
Chatterjee, S; Struhl, K (1995-04-27). "Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain". Nature. 374 (6525): 820–822. doi:10.1038/374820a0. PMID 7723828. S2CID 4325887.
Kuras, L; Struhl, K (1999-06-10). "Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme". Nature. 399 (6736): 609–613. doi:10.1038/21239. PMID 10376605. S2CID 204993837.
Cormack, BP; Struhl, K (1992-05-15). "The TATA-binding protein is required for transcription by all three nuclear RNA polymerases in yeast cells". Cell. 69 (4): 685–696. doi:10.1016/0092-8674(92)90232-2. PMID 1586947. S2CID 7419671.
Cormack, BP; Struhl, K (1993-10-08). "Regional codon randomization: defining a TATA-binding protein surface required for RNA polymerase III transcription". Science. 262 (5131): 244–248. doi:10.1126/science.8211143. PMID 8211143.
Cawley, S.; et al. (2004-02-20). "Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of non-coding RNAs". Cell. 116 (4): 499–509. doi:10.1016/S0092-8674(04)00127-8. PMID 14980218. S2CID 7793221.
Yang, Annie; Zhu, Zhou; Kapranov, Philipp; McKeon, Frank; Church, George M; Gingeras, Thomas R; Struhl, Kevin (2006-11-17). "Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells". Molecular Cell. 24 (4): 593–602. doi:10.1016/j.molcel.2006.10.018. PMID 17188034.
Stargell, LA; Struhl, K (1995-07-07). "The TBP-TFIIA interaction in the response to acidic activators in vivo". Science. 269 (5220): 75–78. doi:10.1126/science.7604282. PMID 7604282.
Lee, M; Struhl, K (1995-07-11). "Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo". Molecular and Cellular Biology. 15 (10): 5461–5469. doi:10.1128/MCB.15.10.5461. PMC 230796. PMID 7565697.
Petrenko, Natalia; Yi, Jin; Dong, Liguo; Wong, Koon Ho; Struhl, Kevin (2019-01-25). "Requirements for RNA polymerase II preinitiation complex formation in vivo". eLife. 8. doi:10.7554/eLife.43654.023. PMC 6366898. PMID 30681409.
Wong, Koon Ho; Yi, Jin; Struhl, Kevin (2014-05-22). "TFIIH phosphorylation of the Pol II CTD stimulates Mediator dissociation from the preinitiation complex and promoter escape". Molecular Cell. 54 (4): 601–612. doi:10.1016/j.molcel.2014.03.024. PMC 4035452. PMID 24746699.
Yi, Jin; Eser, Umut; Struhl, Kevin; Churchman, L Stirling (2017-08-24). "The ground state and evolution of promoter regions directionality". Cell. 170 (5): 889–898.e10. doi:10.1016/j.cell.2017.07.006. PMC 5576552. PMID 28803729.
Struhl, Kevin (February 2007). "Transcriptional noise and the fidelity of initiation by RNA polymerase II". Nature Structural & Molecular Biology. 14 (2): 103–105. doi:10.1038/nsmb0207-103. PMID 17277804. S2CID 29398526.
Moqtaderi, Zarmik; Bai, Yu; Poon, David; Weil, P Anthony; Struhl, Kevin (1996-09-12). "TBP-associated factors are not generally required for transcriptional activation in yeast". Nature. 383 (6596): 188–191. doi:10.1038/383188a0. PMID 8774887. S2CID 4351320.
Kuras, Laurent; Kosa, Peter; Mencia, Mario; Struhl, Kevin (2000-05-19). "TAF-containing and TAF-independent forms of transcriptionally active TBP in vivo". Science. 288 (5469): 1244–1248. doi:10.1126/science.288.5469.1244. PMID 10818000.
Mencia, Mario; Moqtaderi, Zarmik; Geisberg, Joseph V; Kuras, Laurent; Struhl, Kevin (April 2002). "Activator-specific recruitment of TFIID and regulation of ribosomal protein genes in yeast". Molecular Cell. 9 (4): 823–833. doi:10.1016/S1097-2765(02)00490-2. PMID 11983173.
Fan, Xiaochun; Chou, Danny M; Struhl, Kevin (2006-01-22). "Activator-specific recruitment of Mediator in vivo". Nature Structural & Molecular Biology. 13 (2): 117–120. doi:10.1038/nsmb1049. PMID 16429153. S2CID 20626638.
Petrenko, Natalia; Jin, Yi; Wong, Koon Ho; Struhl, Kevin (2016-11-03). "Mediator Undergoes a Compositional Change during Transcriptional Activation". Molecular Cell. 64 (3): 443–454. doi:10.1016/j.molcel.2016.09.015. PMC 5096951. PMID 27773675.
Klein, C; Struhl, K (March 1994). "Protein kinase A mediates growth-regulated expression of yeast ribosomal protein genes by modulating RAP1 transcriptional activity". Molecular and Cellular Biology. 14 (3): 1920–1928. doi:10.1128/mcb.14.3.1920-1928.1994. PMC 358550. PMID 8114723.
Wade, Joseph T; Hall, Daniel B; Struhl, Kevin (2004-12-23). "The transcription factor Ifh1 is a key regulator of yeast ribosomal protein genes". Nature. 432 (7020): 1054–1058. doi:10.1038/nature03175. PMID 15616568. S2CID 4334147.
Tzamarias, D; Struhl, K (1994-06-30). "Functional dissection of the yeast Cyc8-Tup1 transcriptional corepressor complex". Nature. 369 (6483): 758–761. doi:10.1038/369758a0. PMID 8008070. S2CID 4304771.
Wong, Koon Ho; Struhl, Kevin (2011-12-01). "The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein". Genes & Development. 25 (23): 2525–2539. doi:10.1101/gad.179275.111. PMC 3243062. PMID 22156212.
Proft, M; Struhl, K (June 2002). "Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress". Molecular Cell. 9 (6): 1307–1317. doi:10.1016/S1097-2765(02)00557-9. PMID 12086627.
Proft, M; Struhl, K (2004-08-06). "A MAP kinase-mediated stress relief response that precedes and regulates the timing of transcriptional induction". Cell. 118 (3): 351–361. doi:10.1016/j.cell.2004.07.016. PMID 15294160. S2CID 2022911.
Mason, Paul B; Struhl, Kevin (2005-03-18). "Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo". Molecular Cell. 17 (6): 831–840. doi:10.1016/j.molcel.2005.02.017. PMID 15780939.
Geisberg, Joseph V; Moqtaderi, Zarmik; Struhl, Kevin (2020-08-26). "The transcriptional elongation rate regulates alternative polyadenylation in yeast". eLife. 9. doi:10.7554/eLife.59810.sa2. PMC 7532003. PMID 32845240.
Geisberg, Joseph V; Moqtaderi, Zarmik; Fong, Nova; Erickson, Benjamin; Bentley, David L; Struhl, Kevin (2022-11-24). "Nucleotide-level linkage of transcriptional elongation and polyadenylation". eLife. 11. doi:10.7554/eLife.83153.sa2. PMC 9721619. PMID 36421680.
Geisberg, Joseph V; Moqtaderi, Zarmik; Fan, Xiaochun; Ozsolak, Fatih; Struhl, Kevin (2014-02-13). "Global analysis of mRNA isoform half-lives reveals stabilizing and destabilizing elements in yeast". Cell. 156 (4): 812–824. doi:10.1016/j.cell.2013.12.026. PMC 3939777. PMID 24529382.
Moqtaderi, Zarmik; Geisberg, Joseph V; Struhl, Kevin (October 2018). "Extensive structural differences of closely related 3' mRNA isoforms: links to Pab1 binding and mRNA stability". Molecular Cell. 72 (5): 849–861.e6. doi:10.1016/j.molcel.2018.08.044. PMC 6289678. PMID 30318446.
Reppas, Nikos B; Wade, Joseph T; Church, George M; Struhl, Kevin (2006-12-08). "The transition between transcriptional initiation and elongation in E. coli is highly variable and often rate-limiting". Molecular Cell. 24 (5): 747–757. doi:10.1016/j.molcel.2006.10.030. PMID 17157257.
Wade, Joseph T; Roa, Daniel Castro; Grainger, David C; Hurd, Douglas; Busby, Stephen JW; Struhl, Kevin; Nudler, Evgeny (2006-08-06). "Extensive functional overlap between σ factors in Escherichia coli". Nature Structural & Molecular Biology. 13 (9): 806–814. doi:10.1038/nsmb1130. PMID 16892065. S2CID 19816595.
Iyer, V; Struhl, K (June 1995). "Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic structure". The EMBO Journal. 14 (11): 2570–2579. doi:10.1002/j.1460-2075.1995.tb07255.x. PMC 398371. PMID 7781610.
Sekinger, Edward A; Moqtaderi, Zarmik; Struhl, Kevin (2005-06-10). "Intrinsic histone-DNA interactions and low nucleosome density are important for preferential accessibility of promoter regions in yeast". Molecular Cell. 18 (6): 735–748. doi:10.1016/j.molcel.2005.05.003. PMID 15949447.
Zhang, Yong; Moqtaderi, Zarmik; Rattner, Barbara P; Euskirchen, Ghia; Snyder, Michael; Kadonaga, James T; Liu, X Shirley; Struhl, Kevin (2009-07-20). "Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo". Nature Structural & Molecular Biology. 16 (8): 847–852. doi:10.1038/nsmb.1636. PMC 2823114. PMID 19620965. S2CID 11805076.
Hughes, Amanda L; Jin, Yi; Rando, Oliver J; Struhl, Kevin (2012-10-12). "A Functional Evolutionary Approach to Identify Determinants of Nucleosome Positioning: A Unifying Model for Establishing the Genome-wide Pattern". Molecular Cell. 48 (1): 5–15. doi:10.1016/j.molcel.2012.07.003. PMC 3472102. PMID 22885008.
Kadosh, David; Struhl, Kevin (1997-05-02). "Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters". Cell. 89 (3): 365–371. doi:10.1016/S0092-8674(00)80217-2. PMID 9150136. S2CID 15115179.
Kadosh, David; Struhl, Kevin (September 1998). "Targeted Recruitment of the Sin3-Rpd3 Histone Deacetylase Complex Generates a Highly Localized Domain of Repressed Chromatin In Vivo". Molecular and Cellular Biology. 18 (9): 5121–5127. doi:10.1128/MCB.18.9.5121. PMC 109097. PMID 9710596.
Ng, Huck Hui; Robert, Francois; Young, Richard A; Struhl, Kevin (March 2003). "Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity". Molecular Cell. 11 (3): 709–719. doi:10.1016/S1097-2765(03)00092-3. PMID 12667453.
Schwabish, Marc A; Struhl, Kevin (December 2004). "Evidence for Eviction and Rapid Deposition of Histones upon Transcriptional Elongation by RNA Polymerase II". Molecular and Cellular Biology. 24 (23): 10111–10117. doi:10.1128/MCB.24.23.10111-10117.2004. PMC 529037. PMID 15542822.
Ng, Huck Hui; Feng, Qin; Wang, Hengbin; Erdjument-Bromage, Hediye; Tempst, Paul; Zhang, Yi; Struhl, Kevin (2002). "Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association". Genes & Development. 16 (12): 1518–1527. doi:10.1101/gad.1001502. PMC 186335. PMID 12080090.
Ng, Huck Hui; Ciccone, David N; Morshead, Katrina B; Oettinger, Marjorie A; Struhl, Kevin (2003-02-06). "Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: A potential mechanism for position-effect variegation". PNAS. 100 (4): 1820–1825. doi:10.1073/pnas.0437846100. PMC 149917. PMID 12574507.
Miotto, Benoit; Struhl, Kevin (2008). "HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1". Genes & Development. 22 (19): 2633–2638. doi:10.1101/gad.1674108. PMC 2559906. PMID 18832067.
Miotto, Benoit; Struhl, Kevin (2010-01-15). "HBO1 Histone Acetylase Activity Is Essential for DNA Replication Licensing and Inhibited by Geminin". Molecular Cell. 37 (1): 57–66. doi:10.1016/j.molcel.2009.12.012. PMC 2818871. PMID 20129055.
Miotto, Benoit; Struhl, Kevin (2011-10-07). "JNK1 Phosphorylation of Cdt1 Inhibits Recruitment of HBO1 Histone Acetylase and Blocks Replication Licensing in Response to Stress". Molecular Cell. 44 (1): 62–71. doi:10.1016/j.molcel.2011.06.021. PMC 3190045. PMID 21856198.
Miotto, Benoit; Ji, Zhe; Struhl, Kevin (2016-06-14). "Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers". PNAS. 113 (33): 4810–4819. doi:10.1073/pnas.1609060113. PMC 4995967. PMID 27436900.
Iliopoulos, Dimitrios; Hirsch, Heather A; Struhl, Kevin (2009-11-13). "An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation". Cell. 139 (4): 693–706. doi:10.1016/j.cell.2009.10.014. PMC 2783826. PMID 19878981.
He, Lizhi; Pratt, Henry; Gao, Mingshi; Wei, Fengxiang; Weng, Zhiping; Struhl, Kevin (2021-08-21). "YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation". eLife. 10. doi:10.7554/eLife.67312. PMC 8463077. PMID 34463254.
Iliopoulos, Dimitrios; Jaeger, Savina A; Hirsch, Heather A; Bulyk, Martha L; Struhl, Kevin (2010-08-27). "STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer". Molecular Cell. 39 (4): 493–506. doi:10.1016/j.molcel.2010.07.023. PMC 2929389. PMID 20797623.
Ji, Zhe; He, Lizhi; Regev, Aviv; Struhl, Kevin (2019-03-25). "Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers". PNAS. 116 (19): 9453–9462. doi:10.1073/pnas.1821068116. PMC 6511065. PMID 30910960.
Iliopoulos, Dimitrios; Hirsch, Heather A; Wang, Guannan; Struhl, Kevin (2011-01-10). "Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion". PNAS. 108 (4): 1397–1402. doi:10.1073/pnas.1018898108. PMC 3029760. PMID 21220315.
Iliopoulos, Dimitrios; Lindahl-Allen, Marianne; Polytarchou, Christos; Hirsch, Heather A; Tsichlis, Philip N; Struhl, Kevin (2010-09-10). "Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells". Molecular Cell. 39 (5): 761–772. doi:10.1016/j.molcel.2010.08.013. PMC 2938080. PMID 20832727.
Polytarchou, Christos; Iliopoulos, Dimitrios; Struhl, Kevin (2012-08-20). "An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state". PNAS. 109 (36): 14470–14475. doi:10.1073/pnas.1212811109. PMC 3437881. PMID 22908280.
Hirsch, Heather A; Iliopoulos, Dimitrios; Tsichlis, Philip N; Struhl, Kevin (2009-10-01). "Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission". Cancer Research. 69 (19): 7507–7511. doi:10.1158/0008-5472.CAN-09-2994. PMC 2756324. PMID 19752085.
Iliopoulos, Dimitrios; Hirsch, Heather A; Struhl, Kevin (2011-04-29). "Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types". Cancer Research. 71 (9): 3196–3201. doi:10.1158/0008-5472.CAN-10-3471. PMC 3085572. PMID 21415163.
Hirsch, Heather A; Iliopoulos, Dimitrios; Struhl, Kevin (2012-12-31). "Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth". PNAS. 110 (3): 972–977. doi:10.1073/pnas.1221055110. PMC 3549132. PMID 23277563.

dx.doi.org

Hope, IA; Struhl, K (November 1988). "GCN4 protein, synthesized in vitro, binds to HIS3 regulatory sequences: implications for the general control of amino acid biosynthetic genes in yeast". Cell. 43 (1): 177–188. doi:10.1016/0092-8674(85)90022-4. PMID 3907851. S2CID 22627291.
Hope, IA; Struhl, K (1986-09-12). "Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast". Cell. 46 (6): 885–894. doi:10.1016/0092-8674(86)90070-X. PMID 3530496. S2CID 40730692.
Struhl, Kevin (1987-09-11). "The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator are functionally homologous". Cell. 50 (6): 841–846. doi:10.1016/0092-8674(87)90511-3. PMID 3040261. S2CID 29588878.

harvard.edu

ui.adsabs.harvard.edu

Struhl, K; Davis, RW (1977-12-01). "Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3)". PNAS. 74 (12): 5255–5259. Bibcode:1977PNAS...74.5255S. doi:10.1073/pnas.74.12.5255. PMC 431671. PMID 341150.
Struhl, K; Cameron, JR; Davis, RW (1976-05-01). "Functional genetic expression of eukaryotic DNA in Escherichia coli". PNAS. 73 (5): 1471–1475. Bibcode:1976PNAS...73.1471S. doi:10.1073/pnas.73.5.1471. PMC 430318. PMID 775490.
Struhl, K; Stinchcomb, DT; Scherer, S; Davis, RW (1979-03-01). "High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules". PNAS. 76 (3): 1035–1039. Bibcode:1979PNAS...76.1035S. doi:10.1073/pnas.76.3.1035. PMC 383183. PMID 375221.
Stinchcomb, DT; Struhl, K; Davis, RW (1979-11-01). "Isolation and characterization of a yeast chromosomal replicator". Nature. 282 (5734): 39–43. Bibcode:1979Natur.282...39S. doi:10.1038/282039a0. PMID 388229. S2CID 4326901.
Struhl, Kevin (1981-07-01). "Deletion mapping a eukaryotic promoter". PNAS. 78 (7): 4461–4465. Bibcode:1981PNAS...78.4461S. doi:10.1073/pnas.78.7.4461. PMC 319811. PMID 7027262.
Struhl, Kevin (1985-12-01). "Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast". PNAS. 82 (24): 8419–8423. Bibcode:1985PNAS...82.8419S. doi:10.1073/pnas.82.24.8419. PMC 390927. PMID 3909145.
Chen, W; Struhl, K (1988-04-01). "Saturation mutagenesis of a yeast his3 TATA element: genetic evidence for a specific TATA-binding protein". PNAS. 85 (8): 2691–2695. Bibcode:1988PNAS...85.2691C. doi:10.1073/pnas.85.8.2691. PMC 280064. PMID 3282236.
Struhl, Kevin (1985-10-01). "Negative control at a distance mediates catabolite repression in yeast". Nature. 317 (6040): 822–824. Bibcode:1985Natur.317..822S. doi:10.1038/317822a0. PMID 3903516. S2CID 2404872.
Weiss, Michael A; Ellenberger, Thomas; Wobbe, C Richard; Lee, Jonathan P; Harrison, Stephen C; Struhl, Kevin (1990). "Folding transition in the DNA-binding domain of GCN4 on specific binding to DNA". Nature. 347 (6293): 575–578. Bibcode:1990Natur.347..575W. doi:10.1038/347575a0. PMID 2145515. S2CID 4366430.
Hope, IA; Mahadevan, S; Struhl, K (1988-06-16). "Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein". Nature. 333 (6174): 635–640. Bibcode:1988Natur.333..635H. doi:10.1038/333635a0. PMID 3287180. S2CID 2635634.
Struhl, Kevin (1988-04-14). "The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast". Nature. 332 (6165): 649–650. Bibcode:1988Natur.332..649S. doi:10.1038/332649a0. PMID 3128739. S2CID 4350206.

nam.edu

"National Academy of Medicine". National Academy of Medicine. 2015.

nasonline.org

"National Academy of Sciences". National Academy of Sciences. 2014.

nature.com

Stinchcomb, DT; Struhl, K; Davis, RW (1979-11-01). "Isolation and characterization of a yeast chromosomal replicator". Nature. 282 (5734): 39–43. Bibcode:1979Natur.282...39S. doi:10.1038/282039a0. PMID 388229. S2CID 4326901.
Struhl, Kevin (1982-11-18). "Regulatory sites for his3 expression in yeast". Nature. 300 (5889): 285–286. doi:10.1038/300284a0. PMID 6755264. S2CID 4308484.
Struhl, Kevin (1985-10-01). "Negative control at a distance mediates catabolite repression in yeast". Nature. 317 (6040): 822–824. Bibcode:1985Natur.317..822S. doi:10.1038/317822a0. PMID 3903516. S2CID 2404872.
Sellers, JW; Struhl, K (1989-09-07). "Changing fos oncoprotein to a DNA-binding protein with GCN4 dimerization specificity by swapping "leucine zippers"". Nature. 341 (6237): 74–76. doi:10.1038/341074a0. PMID 2505087. S2CID 4253004.
Weiss, Michael A; Ellenberger, Thomas; Wobbe, C Richard; Lee, Jonathan P; Harrison, Stephen C; Struhl, Kevin (1990). "Folding transition in the DNA-binding domain of GCN4 on specific binding to DNA". Nature. 347 (6293): 575–578. Bibcode:1990Natur.347..575W. doi:10.1038/347575a0. PMID 2145515. S2CID 4366430.
Hope, IA; Mahadevan, S; Struhl, K (1988-06-16). "Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein". Nature. 333 (6174): 635–640. Bibcode:1988Natur.333..635H. doi:10.1038/333635a0. PMID 3287180. S2CID 2635634.
Struhl, Kevin (1988-04-14). "The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast". Nature. 332 (6165): 649–650. Bibcode:1988Natur.332..649S. doi:10.1038/332649a0. PMID 3128739. S2CID 4350206.
Chatterjee, S; Struhl, K (1995-04-27). "Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain". Nature. 374 (6525): 820–822. doi:10.1038/374820a0. PMID 7723828. S2CID 4325887.
Kuras, L; Struhl, K (1999-06-10). "Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme". Nature. 399 (6736): 609–613. doi:10.1038/21239. PMID 10376605. S2CID 204993837.
Struhl, Kevin (February 2007). "Transcriptional noise and the fidelity of initiation by RNA polymerase II". Nature Structural & Molecular Biology. 14 (2): 103–105. doi:10.1038/nsmb0207-103. PMID 17277804. S2CID 29398526.
Moqtaderi, Zarmik; Bai, Yu; Poon, David; Weil, P Anthony; Struhl, Kevin (1996-09-12). "TBP-associated factors are not generally required for transcriptional activation in yeast". Nature. 383 (6596): 188–191. doi:10.1038/383188a0. PMID 8774887. S2CID 4351320.
Fan, Xiaochun; Chou, Danny M; Struhl, Kevin (2006-01-22). "Activator-specific recruitment of Mediator in vivo". Nature Structural & Molecular Biology. 13 (2): 117–120. doi:10.1038/nsmb1049. PMID 16429153. S2CID 20626638.
Wade, Joseph T; Hall, Daniel B; Struhl, Kevin (2004-12-23). "The transcription factor Ifh1 is a key regulator of yeast ribosomal protein genes". Nature. 432 (7020): 1054–1058. doi:10.1038/nature03175. PMID 15616568. S2CID 4334147.
Tzamarias, D; Struhl, K (1994-06-30). "Functional dissection of the yeast Cyc8-Tup1 transcriptional corepressor complex". Nature. 369 (6483): 758–761. doi:10.1038/369758a0. PMID 8008070. S2CID 4304771.
Wade, Joseph T; Roa, Daniel Castro; Grainger, David C; Hurd, Douglas; Busby, Stephen JW; Struhl, Kevin; Nudler, Evgeny (2006-08-06). "Extensive functional overlap between σ factors in Escherichia coli". Nature Structural & Molecular Biology. 13 (9): 806–814. doi:10.1038/nsmb1130. PMID 16892065. S2CID 19816595.

nih.gov

pubmed.ncbi.nlm.nih.gov

Struhl, Kevin (1995). "Yeast Transcriptional Regulatory Mechanisms". Annual Review of Genetics. 29: 651–674. doi:10.1146/annurev.ge.29.120195.003251. PMID 8825489.
Struhl, K; Davis, RW (1977-12-01). "Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3)". PNAS. 74 (12): 5255–5259. Bibcode:1977PNAS...74.5255S. doi:10.1073/pnas.74.12.5255. PMC 431671. PMID 341150.
Struhl, K; Cameron, JR; Davis, RW (1976-05-01). "Functional genetic expression of eukaryotic DNA in Escherichia coli". PNAS. 73 (5): 1471–1475. Bibcode:1976PNAS...73.1471S. doi:10.1073/pnas.73.5.1471. PMC 430318. PMID 775490.
Struhl, K; Stinchcomb, DT; Scherer, S; Davis, RW (1979-03-01). "High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules". PNAS. 76 (3): 1035–1039. Bibcode:1979PNAS...76.1035S. doi:10.1073/pnas.76.3.1035. PMC 383183. PMID 375221.
Stinchcomb, DT; Struhl, K; Davis, RW (1979-11-01). "Isolation and characterization of a yeast chromosomal replicator". Nature. 282 (5734): 39–43. Bibcode:1979Natur.282...39S. doi:10.1038/282039a0. PMID 388229. S2CID 4326901.
Struhl, Kevin (1981-07-01). "Deletion mapping a eukaryotic promoter". PNAS. 78 (7): 4461–4465. Bibcode:1981PNAS...78.4461S. doi:10.1073/pnas.78.7.4461. PMC 319811. PMID 7027262.
Struhl, Kevin (1982-11-18). "Regulatory sites for his3 expression in yeast". Nature. 300 (5889): 285–286. doi:10.1038/300284a0. PMID 6755264. S2CID 4308484.
Struhl, Kevin (1985-12-01). "Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast". PNAS. 82 (24): 8419–8423. Bibcode:1985PNAS...82.8419S. doi:10.1073/pnas.82.24.8419. PMC 390927. PMID 3909145.
Chen, W; Struhl, K (1988-04-01). "Saturation mutagenesis of a yeast his3 TATA element: genetic evidence for a specific TATA-binding protein". PNAS. 85 (8): 2691–2695. Bibcode:1988PNAS...85.2691C. doi:10.1073/pnas.85.8.2691. PMC 280064. PMID 3282236.
Struhl, Kevin (1986-05-29). "Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms". Molecular and Cellular Biology. 6 (11): 3847–3853. doi:10.1128/mcb.6.11.3847-3853.1986. PMC 367147. PMID 3540601.
Chen, W; Struhl, K (1985-12-01). "Yeast mRNA initiation sites are determined primarily by specific sequences, not by the distance from the TATA element". The EMBO Journal. 4 (12): 3273–3280. doi:10.1002/j.1460-2075.1985.tb04077.x. PMC 554654. PMID 3912167.
Struhl, Kevin (1985-10-01). "Negative control at a distance mediates catabolite repression in yeast". Nature. 317 (6040): 822–824. Bibcode:1985Natur.317..822S. doi:10.1038/317822a0. PMID 3903516. S2CID 2404872.
Hope, IA; Struhl, K (November 1988). "GCN4 protein, synthesized in vitro, binds to HIS3 regulatory sequences: implications for the general control of amino acid biosynthetic genes in yeast". Cell. 43 (1): 177–188. doi:10.1016/0092-8674(85)90022-4. PMID 3907851. S2CID 22627291.
Oliphant, AR; Brandl, CJ; Struhl, K (1989-07-01). "Defining sequence specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: Analysis of the yeast GCN4 protein". Molecular and Cellular Biology. 9 (7): 2944–2949. doi:10.1128/mcb.9.7.2944-2949.1989. PMC 362762. PMID 2674675.
Hope, IA; Struhl, K (1987-09-01). "GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA". The EMBO Journal. 6 (9): 2781–2784. doi:10.1002/j.1460-2075.1987.tb02573.x. PMC 553703. PMID 3678204.
Sellers, JW; Struhl, K (1989-09-07). "Changing fos oncoprotein to a DNA-binding protein with GCN4 dimerization specificity by swapping "leucine zippers"". Nature. 341 (6237): 74–76. doi:10.1038/341074a0. PMID 2505087. S2CID 4253004.
Ellenberger, Thomas E; Brandl, Christopher J; Struhl, Kevin; Harrison, Stephen C (1992-12-24). "The GCN4 basic-region-leucine zipper binds DNA as a dimer of uninterrupted a-helices: crystal structure of the protein-DNA complex". Cell. 71 (7): 1223–1237. doi:10.1016/S0092-8674(05)80070-4. PMID 1473154. S2CID 13548424.
Weiss, Michael A; Ellenberger, Thomas; Wobbe, C Richard; Lee, Jonathan P; Harrison, Stephen C; Struhl, Kevin (1990). "Folding transition in the DNA-binding domain of GCN4 on specific binding to DNA". Nature. 347 (6293): 575–578. Bibcode:1990Natur.347..575W. doi:10.1038/347575a0. PMID 2145515. S2CID 4366430.
Hope, IA; Struhl, K (1986-09-12). "Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast". Cell. 46 (6): 885–894. doi:10.1016/0092-8674(86)90070-X. PMID 3530496. S2CID 40730692.
Hope, IA; Mahadevan, S; Struhl, K (1988-06-16). "Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein". Nature. 333 (6174): 635–640. Bibcode:1988Natur.333..635H. doi:10.1038/333635a0. PMID 3287180. S2CID 2635634.
Struhl, Kevin (1987-09-11). "The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator are functionally homologous". Cell. 50 (6): 841–846. doi:10.1016/0092-8674(87)90511-3. PMID 3040261. S2CID 29588878.
Struhl, Kevin (1988-04-14). "The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast". Nature. 332 (6165): 649–650. Bibcode:1988Natur.332..649S. doi:10.1038/332649a0. PMID 3128739. S2CID 4350206.
Chen, W; Tabor, S; Struhl, K (1987-09-25). "Distinguishing between mechanisms of eukaryotic transcriptional activation with bacteriophage T7 RNA polymerase". Cell. 266 (5183): 280–282. doi:10.1126/science.7939664. PMID 7939664.
Klein, C; Struhl, K (1994-10-19). "Increased recruitment of TATA-binding protein to the promoter by transcriptional activation domains in vivo". Science. 266 (5183): 280–282. doi:10.1126/science.7939664. PMID 7939664.
Keaveney, M; Struhl, K (May 1998). "Activator-mediated recruitment of the RNA polymerase II machinery is the predominant mechanism for transcriptional activation in yeast". Molecular Cell. 1 (6): 917–924. doi:10.1016/S1097-2765(00)80091-X. PMID 9660975.
Chatterjee, S; Struhl, K (1995-04-27). "Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain". Nature. 374 (6525): 820–822. doi:10.1038/374820a0. PMID 7723828. S2CID 4325887.
Kuras, L; Struhl, K (1999-06-10). "Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme". Nature. 399 (6736): 609–613. doi:10.1038/21239. PMID 10376605. S2CID 204993837.
Cormack, BP; Struhl, K (1992-05-15). "The TATA-binding protein is required for transcription by all three nuclear RNA polymerases in yeast cells". Cell. 69 (4): 685–696. doi:10.1016/0092-8674(92)90232-2. PMID 1586947. S2CID 7419671.
Cormack, BP; Struhl, K (1993-10-08). "Regional codon randomization: defining a TATA-binding protein surface required for RNA polymerase III transcription". Science. 262 (5131): 244–248. doi:10.1126/science.8211143. PMID 8211143.
Cawley, S.; et al. (2004-02-20). "Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of non-coding RNAs". Cell. 116 (4): 499–509. doi:10.1016/S0092-8674(04)00127-8. PMID 14980218. S2CID 7793221.
Yang, Annie; Zhu, Zhou; Kapranov, Philipp; McKeon, Frank; Church, George M; Gingeras, Thomas R; Struhl, Kevin (2006-11-17). "Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells". Molecular Cell. 24 (4): 593–602. doi:10.1016/j.molcel.2006.10.018. PMID 17188034.
Stargell, LA; Struhl, K (1995-07-07). "The TBP-TFIIA interaction in the response to acidic activators in vivo". Science. 269 (5220): 75–78. doi:10.1126/science.7604282. PMID 7604282.
Lee, M; Struhl, K (1995-07-11). "Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo". Molecular and Cellular Biology. 15 (10): 5461–5469. doi:10.1128/MCB.15.10.5461. PMC 230796. PMID 7565697.
Petrenko, Natalia; Yi, Jin; Dong, Liguo; Wong, Koon Ho; Struhl, Kevin (2019-01-25). "Requirements for RNA polymerase II preinitiation complex formation in vivo". eLife. 8. doi:10.7554/eLife.43654.023. PMC 6366898. PMID 30681409.
Wong, Koon Ho; Yi, Jin; Struhl, Kevin (2014-05-22). "TFIIH phosphorylation of the Pol II CTD stimulates Mediator dissociation from the preinitiation complex and promoter escape". Molecular Cell. 54 (4): 601–612. doi:10.1016/j.molcel.2014.03.024. PMC 4035452. PMID 24746699.
Yi, Jin; Eser, Umut; Struhl, Kevin; Churchman, L Stirling (2017-08-24). "The ground state and evolution of promoter regions directionality". Cell. 170 (5): 889–898.e10. doi:10.1016/j.cell.2017.07.006. PMC 5576552. PMID 28803729.
Struhl, Kevin (February 2007). "Transcriptional noise and the fidelity of initiation by RNA polymerase II". Nature Structural & Molecular Biology. 14 (2): 103–105. doi:10.1038/nsmb0207-103. PMID 17277804. S2CID 29398526.
Moqtaderi, Zarmik; Bai, Yu; Poon, David; Weil, P Anthony; Struhl, Kevin (1996-09-12). "TBP-associated factors are not generally required for transcriptional activation in yeast". Nature. 383 (6596): 188–191. doi:10.1038/383188a0. PMID 8774887. S2CID 4351320.
Kuras, Laurent; Kosa, Peter; Mencia, Mario; Struhl, Kevin (2000-05-19). "TAF-containing and TAF-independent forms of transcriptionally active TBP in vivo". Science. 288 (5469): 1244–1248. doi:10.1126/science.288.5469.1244. PMID 10818000.
Mencia, Mario; Moqtaderi, Zarmik; Geisberg, Joseph V; Kuras, Laurent; Struhl, Kevin (April 2002). "Activator-specific recruitment of TFIID and regulation of ribosomal protein genes in yeast". Molecular Cell. 9 (4): 823–833. doi:10.1016/S1097-2765(02)00490-2. PMID 11983173.
Fan, Xiaochun; Chou, Danny M; Struhl, Kevin (2006-01-22). "Activator-specific recruitment of Mediator in vivo". Nature Structural & Molecular Biology. 13 (2): 117–120. doi:10.1038/nsmb1049. PMID 16429153. S2CID 20626638.
Petrenko, Natalia; Jin, Yi; Wong, Koon Ho; Struhl, Kevin (2016-11-03). "Mediator Undergoes a Compositional Change during Transcriptional Activation". Molecular Cell. 64 (3): 443–454. doi:10.1016/j.molcel.2016.09.015. PMC 5096951. PMID 27773675.
Klein, C; Struhl, K (March 1994). "Protein kinase A mediates growth-regulated expression of yeast ribosomal protein genes by modulating RAP1 transcriptional activity". Molecular and Cellular Biology. 14 (3): 1920–1928. doi:10.1128/mcb.14.3.1920-1928.1994. PMC 358550. PMID 8114723.
Wade, Joseph T; Hall, Daniel B; Struhl, Kevin (2004-12-23). "The transcription factor Ifh1 is a key regulator of yeast ribosomal protein genes". Nature. 432 (7020): 1054–1058. doi:10.1038/nature03175. PMID 15616568. S2CID 4334147.
Tzamarias, D; Struhl, K (1994-06-30). "Functional dissection of the yeast Cyc8-Tup1 transcriptional corepressor complex". Nature. 369 (6483): 758–761. doi:10.1038/369758a0. PMID 8008070. S2CID 4304771.
Wong, Koon Ho; Struhl, Kevin (2011-12-01). "The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein". Genes & Development. 25 (23): 2525–2539. doi:10.1101/gad.179275.111. PMC 3243062. PMID 22156212.
Proft, M; Struhl, K (June 2002). "Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress". Molecular Cell. 9 (6): 1307–1317. doi:10.1016/S1097-2765(02)00557-9. PMID 12086627.
Proft, M; Struhl, K (2004-08-06). "A MAP kinase-mediated stress relief response that precedes and regulates the timing of transcriptional induction". Cell. 118 (3): 351–361. doi:10.1016/j.cell.2004.07.016. PMID 15294160. S2CID 2022911.
Mason, Paul B; Struhl, Kevin (2005-03-18). "Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo". Molecular Cell. 17 (6): 831–840. doi:10.1016/j.molcel.2005.02.017. PMID 15780939.
Geisberg, Joseph V; Moqtaderi, Zarmik; Struhl, Kevin (2020-08-26). "The transcriptional elongation rate regulates alternative polyadenylation in yeast". eLife. 9. doi:10.7554/eLife.59810.sa2. PMC 7532003. PMID 32845240.
Geisberg, Joseph V; Moqtaderi, Zarmik; Fong, Nova; Erickson, Benjamin; Bentley, David L; Struhl, Kevin (2022-11-24). "Nucleotide-level linkage of transcriptional elongation and polyadenylation". eLife. 11. doi:10.7554/eLife.83153.sa2. PMC 9721619. PMID 36421680.
Geisberg, Joseph V; Moqtaderi, Zarmik; Fan, Xiaochun; Ozsolak, Fatih; Struhl, Kevin (2014-02-13). "Global analysis of mRNA isoform half-lives reveals stabilizing and destabilizing elements in yeast". Cell. 156 (4): 812–824. doi:10.1016/j.cell.2013.12.026. PMC 3939777. PMID 24529382.
Moqtaderi, Zarmik; Geisberg, Joseph V; Struhl, Kevin (October 2018). "Extensive structural differences of closely related 3' mRNA isoforms: links to Pab1 binding and mRNA stability". Molecular Cell. 72 (5): 849–861.e6. doi:10.1016/j.molcel.2018.08.044. PMC 6289678. PMID 30318446.
Reppas, Nikos B; Wade, Joseph T; Church, George M; Struhl, Kevin (2006-12-08). "The transition between transcriptional initiation and elongation in E. coli is highly variable and often rate-limiting". Molecular Cell. 24 (5): 747–757. doi:10.1016/j.molcel.2006.10.030. PMID 17157257.
Wade, Joseph T; Roa, Daniel Castro; Grainger, David C; Hurd, Douglas; Busby, Stephen JW; Struhl, Kevin; Nudler, Evgeny (2006-08-06). "Extensive functional overlap between σ factors in Escherichia coli". Nature Structural & Molecular Biology. 13 (9): 806–814. doi:10.1038/nsmb1130. PMID 16892065. S2CID 19816595.
Iyer, V; Struhl, K (June 1995). "Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic structure". The EMBO Journal. 14 (11): 2570–2579. doi:10.1002/j.1460-2075.1995.tb07255.x. PMC 398371. PMID 7781610.
Sekinger, Edward A; Moqtaderi, Zarmik; Struhl, Kevin (2005-06-10). "Intrinsic histone-DNA interactions and low nucleosome density are important for preferential accessibility of promoter regions in yeast". Molecular Cell. 18 (6): 735–748. doi:10.1016/j.molcel.2005.05.003. PMID 15949447.
Zhang, Yong; Moqtaderi, Zarmik; Rattner, Barbara P; Euskirchen, Ghia; Snyder, Michael; Kadonaga, James T; Liu, X Shirley; Struhl, Kevin (2009-07-20). "Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo". Nature Structural & Molecular Biology. 16 (8): 847–852. doi:10.1038/nsmb.1636. PMC 2823114. PMID 19620965. S2CID 11805076.
Hughes, Amanda L; Jin, Yi; Rando, Oliver J; Struhl, Kevin (2012-10-12). "A Functional Evolutionary Approach to Identify Determinants of Nucleosome Positioning: A Unifying Model for Establishing the Genome-wide Pattern". Molecular Cell. 48 (1): 5–15. doi:10.1016/j.molcel.2012.07.003. PMC 3472102. PMID 22885008.
Kadosh, David; Struhl, Kevin (1997-05-02). "Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters". Cell. 89 (3): 365–371. doi:10.1016/S0092-8674(00)80217-2. PMID 9150136. S2CID 15115179.
Kadosh, David; Struhl, Kevin (September 1998). "Targeted Recruitment of the Sin3-Rpd3 Histone Deacetylase Complex Generates a Highly Localized Domain of Repressed Chromatin In Vivo". Molecular and Cellular Biology. 18 (9): 5121–5127. doi:10.1128/MCB.18.9.5121. PMC 109097. PMID 9710596.
Ng, Huck Hui; Robert, Francois; Young, Richard A; Struhl, Kevin (March 2003). "Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity". Molecular Cell. 11 (3): 709–719. doi:10.1016/S1097-2765(03)00092-3. PMID 12667453.
Schwabish, Marc A; Struhl, Kevin (December 2004). "Evidence for Eviction and Rapid Deposition of Histones upon Transcriptional Elongation by RNA Polymerase II". Molecular and Cellular Biology. 24 (23): 10111–10117. doi:10.1128/MCB.24.23.10111-10117.2004. PMC 529037. PMID 15542822.
Ng, Huck Hui; Feng, Qin; Wang, Hengbin; Erdjument-Bromage, Hediye; Tempst, Paul; Zhang, Yi; Struhl, Kevin (2002). "Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association". Genes & Development. 16 (12): 1518–1527. doi:10.1101/gad.1001502. PMC 186335. PMID 12080090.
Ng, Huck Hui; Ciccone, David N; Morshead, Katrina B; Oettinger, Marjorie A; Struhl, Kevin (2003-02-06). "Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: A potential mechanism for position-effect variegation". PNAS. 100 (4): 1820–1825. doi:10.1073/pnas.0437846100. PMC 149917. PMID 12574507.
Miotto, Benoit; Struhl, Kevin (2008). "HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1". Genes & Development. 22 (19): 2633–2638. doi:10.1101/gad.1674108. PMC 2559906. PMID 18832067.
Miotto, Benoit; Struhl, Kevin (2010-01-15). "HBO1 Histone Acetylase Activity Is Essential for DNA Replication Licensing and Inhibited by Geminin". Molecular Cell. 37 (1): 57–66. doi:10.1016/j.molcel.2009.12.012. PMC 2818871. PMID 20129055.
Miotto, Benoit; Struhl, Kevin (2011-10-07). "JNK1 Phosphorylation of Cdt1 Inhibits Recruitment of HBO1 Histone Acetylase and Blocks Replication Licensing in Response to Stress". Molecular Cell. 44 (1): 62–71. doi:10.1016/j.molcel.2011.06.021. PMC 3190045. PMID 21856198.
Miotto, Benoit; Ji, Zhe; Struhl, Kevin (2016-06-14). "Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers". PNAS. 113 (33): 4810–4819. doi:10.1073/pnas.1609060113. PMC 4995967. PMID 27436900.
Iliopoulos, Dimitrios; Hirsch, Heather A; Struhl, Kevin (2009-11-13). "An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation". Cell. 139 (4): 693–706. doi:10.1016/j.cell.2009.10.014. PMC 2783826. PMID 19878981.
He, Lizhi; Pratt, Henry; Gao, Mingshi; Wei, Fengxiang; Weng, Zhiping; Struhl, Kevin (2021-08-21). "YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation". eLife. 10. doi:10.7554/eLife.67312. PMC 8463077. PMID 34463254.
Iliopoulos, Dimitrios; Jaeger, Savina A; Hirsch, Heather A; Bulyk, Martha L; Struhl, Kevin (2010-08-27). "STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer". Molecular Cell. 39 (4): 493–506. doi:10.1016/j.molcel.2010.07.023. PMC 2929389. PMID 20797623.
Ji, Zhe; He, Lizhi; Regev, Aviv; Struhl, Kevin (2019-03-25). "Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers". PNAS. 116 (19): 9453–9462. doi:10.1073/pnas.1821068116. PMC 6511065. PMID 30910960.
Iliopoulos, Dimitrios; Hirsch, Heather A; Wang, Guannan; Struhl, Kevin (2011-01-10). "Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion". PNAS. 108 (4): 1397–1402. doi:10.1073/pnas.1018898108. PMC 3029760. PMID 21220315.
Iliopoulos, Dimitrios; Lindahl-Allen, Marianne; Polytarchou, Christos; Hirsch, Heather A; Tsichlis, Philip N; Struhl, Kevin (2010-09-10). "Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells". Molecular Cell. 39 (5): 761–772. doi:10.1016/j.molcel.2010.08.013. PMC 2938080. PMID 20832727.
Polytarchou, Christos; Iliopoulos, Dimitrios; Struhl, Kevin (2012-08-20). "An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state". PNAS. 109 (36): 14470–14475. doi:10.1073/pnas.1212811109. PMC 3437881. PMID 22908280.
Hirsch, Heather A; Iliopoulos, Dimitrios; Tsichlis, Philip N; Struhl, Kevin (2009-10-01). "Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission". Cancer Research. 69 (19): 7507–7511. doi:10.1158/0008-5472.CAN-09-2994. PMC 2756324. PMID 19752085.
Iliopoulos, Dimitrios; Hirsch, Heather A; Struhl, Kevin (2011-04-29). "Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types". Cancer Research. 71 (9): 3196–3201. doi:10.1158/0008-5472.CAN-10-3471. PMC 3085572. PMID 21415163.
Hirsch, Heather A; Iliopoulos, Dimitrios; Struhl, Kevin (2012-12-31). "Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth". PNAS. 110 (3): 972–977. doi:10.1073/pnas.1221055110. PMC 3549132. PMID 23277563.

ncbi.nlm.nih.gov

Struhl, K; Davis, RW (1977-12-01). "Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3)". PNAS. 74 (12): 5255–5259. Bibcode:1977PNAS...74.5255S. doi:10.1073/pnas.74.12.5255. PMC 431671. PMID 341150.
Struhl, K; Cameron, JR; Davis, RW (1976-05-01). "Functional genetic expression of eukaryotic DNA in Escherichia coli". PNAS. 73 (5): 1471–1475. Bibcode:1976PNAS...73.1471S. doi:10.1073/pnas.73.5.1471. PMC 430318. PMID 775490.
Struhl, K; Stinchcomb, DT; Scherer, S; Davis, RW (1979-03-01). "High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules". PNAS. 76 (3): 1035–1039. Bibcode:1979PNAS...76.1035S. doi:10.1073/pnas.76.3.1035. PMC 383183. PMID 375221.
Struhl, Kevin (1981-07-01). "Deletion mapping a eukaryotic promoter". PNAS. 78 (7): 4461–4465. Bibcode:1981PNAS...78.4461S. doi:10.1073/pnas.78.7.4461. PMC 319811. PMID 7027262.
Struhl, Kevin (1985-12-01). "Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast". PNAS. 82 (24): 8419–8423. Bibcode:1985PNAS...82.8419S. doi:10.1073/pnas.82.24.8419. PMC 390927. PMID 3909145.
Chen, W; Struhl, K (1988-04-01). "Saturation mutagenesis of a yeast his3 TATA element: genetic evidence for a specific TATA-binding protein". PNAS. 85 (8): 2691–2695. Bibcode:1988PNAS...85.2691C. doi:10.1073/pnas.85.8.2691. PMC 280064. PMID 3282236.
Struhl, Kevin (1986-05-29). "Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms". Molecular and Cellular Biology. 6 (11): 3847–3853. doi:10.1128/mcb.6.11.3847-3853.1986. PMC 367147. PMID 3540601.
Chen, W; Struhl, K (1985-12-01). "Yeast mRNA initiation sites are determined primarily by specific sequences, not by the distance from the TATA element". The EMBO Journal. 4 (12): 3273–3280. doi:10.1002/j.1460-2075.1985.tb04077.x. PMC 554654. PMID 3912167.
Oliphant, AR; Brandl, CJ; Struhl, K (1989-07-01). "Defining sequence specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: Analysis of the yeast GCN4 protein". Molecular and Cellular Biology. 9 (7): 2944–2949. doi:10.1128/mcb.9.7.2944-2949.1989. PMC 362762. PMID 2674675.
Hope, IA; Struhl, K (1987-09-01). "GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA". The EMBO Journal. 6 (9): 2781–2784. doi:10.1002/j.1460-2075.1987.tb02573.x. PMC 553703. PMID 3678204.
Lee, M; Struhl, K (1995-07-11). "Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo". Molecular and Cellular Biology. 15 (10): 5461–5469. doi:10.1128/MCB.15.10.5461. PMC 230796. PMID 7565697.
Petrenko, Natalia; Yi, Jin; Dong, Liguo; Wong, Koon Ho; Struhl, Kevin (2019-01-25). "Requirements for RNA polymerase II preinitiation complex formation in vivo". eLife. 8. doi:10.7554/eLife.43654.023. PMC 6366898. PMID 30681409.
Wong, Koon Ho; Yi, Jin; Struhl, Kevin (2014-05-22). "TFIIH phosphorylation of the Pol II CTD stimulates Mediator dissociation from the preinitiation complex and promoter escape". Molecular Cell. 54 (4): 601–612. doi:10.1016/j.molcel.2014.03.024. PMC 4035452. PMID 24746699.
Yi, Jin; Eser, Umut; Struhl, Kevin; Churchman, L Stirling (2017-08-24). "The ground state and evolution of promoter regions directionality". Cell. 170 (5): 889–898.e10. doi:10.1016/j.cell.2017.07.006. PMC 5576552. PMID 28803729.
Petrenko, Natalia; Jin, Yi; Wong, Koon Ho; Struhl, Kevin (2016-11-03). "Mediator Undergoes a Compositional Change during Transcriptional Activation". Molecular Cell. 64 (3): 443–454. doi:10.1016/j.molcel.2016.09.015. PMC 5096951. PMID 27773675.
Klein, C; Struhl, K (March 1994). "Protein kinase A mediates growth-regulated expression of yeast ribosomal protein genes by modulating RAP1 transcriptional activity". Molecular and Cellular Biology. 14 (3): 1920–1928. doi:10.1128/mcb.14.3.1920-1928.1994. PMC 358550. PMID 8114723.
Wong, Koon Ho; Struhl, Kevin (2011-12-01). "The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein". Genes & Development. 25 (23): 2525–2539. doi:10.1101/gad.179275.111. PMC 3243062. PMID 22156212.
Geisberg, Joseph V; Moqtaderi, Zarmik; Struhl, Kevin (2020-08-26). "The transcriptional elongation rate regulates alternative polyadenylation in yeast". eLife. 9. doi:10.7554/eLife.59810.sa2. PMC 7532003. PMID 32845240.
Geisberg, Joseph V; Moqtaderi, Zarmik; Fong, Nova; Erickson, Benjamin; Bentley, David L; Struhl, Kevin (2022-11-24). "Nucleotide-level linkage of transcriptional elongation and polyadenylation". eLife. 11. doi:10.7554/eLife.83153.sa2. PMC 9721619. PMID 36421680.
Geisberg, Joseph V; Moqtaderi, Zarmik; Fan, Xiaochun; Ozsolak, Fatih; Struhl, Kevin (2014-02-13). "Global analysis of mRNA isoform half-lives reveals stabilizing and destabilizing elements in yeast". Cell. 156 (4): 812–824. doi:10.1016/j.cell.2013.12.026. PMC 3939777. PMID 24529382.
Moqtaderi, Zarmik; Geisberg, Joseph V; Struhl, Kevin (October 2018). "Extensive structural differences of closely related 3' mRNA isoforms: links to Pab1 binding and mRNA stability". Molecular Cell. 72 (5): 849–861.e6. doi:10.1016/j.molcel.2018.08.044. PMC 6289678. PMID 30318446.
Iyer, V; Struhl, K (June 1995). "Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic structure". The EMBO Journal. 14 (11): 2570–2579. doi:10.1002/j.1460-2075.1995.tb07255.x. PMC 398371. PMID 7781610.
Zhang, Yong; Moqtaderi, Zarmik; Rattner, Barbara P; Euskirchen, Ghia; Snyder, Michael; Kadonaga, James T; Liu, X Shirley; Struhl, Kevin (2009-07-20). "Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo". Nature Structural & Molecular Biology. 16 (8): 847–852. doi:10.1038/nsmb.1636. PMC 2823114. PMID 19620965. S2CID 11805076.
Hughes, Amanda L; Jin, Yi; Rando, Oliver J; Struhl, Kevin (2012-10-12). "A Functional Evolutionary Approach to Identify Determinants of Nucleosome Positioning: A Unifying Model for Establishing the Genome-wide Pattern". Molecular Cell. 48 (1): 5–15. doi:10.1016/j.molcel.2012.07.003. PMC 3472102. PMID 22885008.
Kadosh, David; Struhl, Kevin (September 1998). "Targeted Recruitment of the Sin3-Rpd3 Histone Deacetylase Complex Generates a Highly Localized Domain of Repressed Chromatin In Vivo". Molecular and Cellular Biology. 18 (9): 5121–5127. doi:10.1128/MCB.18.9.5121. PMC 109097. PMID 9710596.
Schwabish, Marc A; Struhl, Kevin (December 2004). "Evidence for Eviction and Rapid Deposition of Histones upon Transcriptional Elongation by RNA Polymerase II". Molecular and Cellular Biology. 24 (23): 10111–10117. doi:10.1128/MCB.24.23.10111-10117.2004. PMC 529037. PMID 15542822.
Ng, Huck Hui; Feng, Qin; Wang, Hengbin; Erdjument-Bromage, Hediye; Tempst, Paul; Zhang, Yi; Struhl, Kevin (2002). "Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association". Genes & Development. 16 (12): 1518–1527. doi:10.1101/gad.1001502. PMC 186335. PMID 12080090.
Ng, Huck Hui; Ciccone, David N; Morshead, Katrina B; Oettinger, Marjorie A; Struhl, Kevin (2003-02-06). "Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: A potential mechanism for position-effect variegation". PNAS. 100 (4): 1820–1825. doi:10.1073/pnas.0437846100. PMC 149917. PMID 12574507.
Miotto, Benoit; Struhl, Kevin (2008). "HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1". Genes & Development. 22 (19): 2633–2638. doi:10.1101/gad.1674108. PMC 2559906. PMID 18832067.
Miotto, Benoit; Struhl, Kevin (2010-01-15). "HBO1 Histone Acetylase Activity Is Essential for DNA Replication Licensing and Inhibited by Geminin". Molecular Cell. 37 (1): 57–66. doi:10.1016/j.molcel.2009.12.012. PMC 2818871. PMID 20129055.
Miotto, Benoit; Struhl, Kevin (2011-10-07). "JNK1 Phosphorylation of Cdt1 Inhibits Recruitment of HBO1 Histone Acetylase and Blocks Replication Licensing in Response to Stress". Molecular Cell. 44 (1): 62–71. doi:10.1016/j.molcel.2011.06.021. PMC 3190045. PMID 21856198.
Miotto, Benoit; Ji, Zhe; Struhl, Kevin (2016-06-14). "Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers". PNAS. 113 (33): 4810–4819. doi:10.1073/pnas.1609060113. PMC 4995967. PMID 27436900.
Iliopoulos, Dimitrios; Hirsch, Heather A; Struhl, Kevin (2009-11-13). "An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation". Cell. 139 (4): 693–706. doi:10.1016/j.cell.2009.10.014. PMC 2783826. PMID 19878981.
He, Lizhi; Pratt, Henry; Gao, Mingshi; Wei, Fengxiang; Weng, Zhiping; Struhl, Kevin (2021-08-21). "YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation". eLife. 10. doi:10.7554/eLife.67312. PMC 8463077. PMID 34463254.
Iliopoulos, Dimitrios; Jaeger, Savina A; Hirsch, Heather A; Bulyk, Martha L; Struhl, Kevin (2010-08-27). "STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer". Molecular Cell. 39 (4): 493–506. doi:10.1016/j.molcel.2010.07.023. PMC 2929389. PMID 20797623.
Ji, Zhe; He, Lizhi; Regev, Aviv; Struhl, Kevin (2019-03-25). "Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers". PNAS. 116 (19): 9453–9462. doi:10.1073/pnas.1821068116. PMC 6511065. PMID 30910960.
Iliopoulos, Dimitrios; Hirsch, Heather A; Wang, Guannan; Struhl, Kevin (2011-01-10). "Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion". PNAS. 108 (4): 1397–1402. doi:10.1073/pnas.1018898108. PMC 3029760. PMID 21220315.
Iliopoulos, Dimitrios; Lindahl-Allen, Marianne; Polytarchou, Christos; Hirsch, Heather A; Tsichlis, Philip N; Struhl, Kevin (2010-09-10). "Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells". Molecular Cell. 39 (5): 761–772. doi:10.1016/j.molcel.2010.08.013. PMC 2938080. PMID 20832727.
Polytarchou, Christos; Iliopoulos, Dimitrios; Struhl, Kevin (2012-08-20). "An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state". PNAS. 109 (36): 14470–14475. doi:10.1073/pnas.1212811109. PMC 3437881. PMID 22908280.
Hirsch, Heather A; Iliopoulos, Dimitrios; Tsichlis, Philip N; Struhl, Kevin (2009-10-01). "Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission". Cancer Research. 69 (19): 7507–7511. doi:10.1158/0008-5472.CAN-09-2994. PMC 2756324. PMID 19752085.
Iliopoulos, Dimitrios; Hirsch, Heather A; Struhl, Kevin (2011-04-29). "Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types". Cancer Research. 71 (9): 3196–3201. doi:10.1158/0008-5472.CAN-10-3471. PMC 3085572. PMID 21415163.
Hirsch, Heather A; Iliopoulos, Dimitrios; Struhl, Kevin (2012-12-31). "Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth". PNAS. 110 (3): 972–977. doi:10.1073/pnas.1221055110. PMC 3549132. PMID 23277563.

nytimes.com

timesmachine.nytimes.com

Friedman, Charles (1964-11-22). "$400,000 Indoor Tennis Center With 4 Clay Courts Opens Here" (PDF). The New York Times.

researchgate.net

Moqtaderi, Zarmik; Geisberg, Joseph V; Struhl, Kevin (October 2018). "Extensive structural differences of closely related 3' mRNA isoforms: links to Pab1 binding and mRNA stability". Molecular Cell. 72 (5): 849–861.e6. doi:10.1016/j.molcel.2018.08.044. PMC 6289678. PMID 30318446.

science.org

Chen, W; Tabor, S; Struhl, K (1987-09-25). "Distinguishing between mechanisms of eukaryotic transcriptional activation with bacteriophage T7 RNA polymerase". Cell. 266 (5183): 280–282. doi:10.1126/science.7939664. PMID 7939664.
Klein, C; Struhl, K (1994-10-19). "Increased recruitment of TATA-binding protein to the promoter by transcriptional activation domains in vivo". Science. 266 (5183): 280–282. doi:10.1126/science.7939664. PMID 7939664.
Cormack, BP; Struhl, K (1993-10-08). "Regional codon randomization: defining a TATA-binding protein surface required for RNA polymerase III transcription". Science. 262 (5131): 244–248. doi:10.1126/science.8211143. PMID 8211143.
Stargell, LA; Struhl, K (1995-07-07). "The TBP-TFIIA interaction in the response to acidic activators in vivo". Science. 269 (5220): 75–78. doi:10.1126/science.7604282. PMID 7604282.
Kuras, Laurent; Kosa, Peter; Mencia, Mario; Struhl, Kevin (2000-05-19). "TAF-containing and TAF-independent forms of transcriptionally active TBP in vivo". Science. 288 (5469): 1244–1248. doi:10.1126/science.288.5469.1244. PMID 10818000.

sciencedirect.com

Ellenberger, Thomas E; Brandl, Christopher J; Struhl, Kevin; Harrison, Stephen C (1992-12-24). "The GCN4 basic-region-leucine zipper binds DNA as a dimer of uninterrupted a-helices: crystal structure of the protein-DNA complex". Cell. 71 (7): 1223–1237. doi:10.1016/S0092-8674(05)80070-4. PMID 1473154. S2CID 13548424.

semanticscholar.org

api.semanticscholar.org

Stinchcomb, DT; Struhl, K; Davis, RW (1979-11-01). "Isolation and characterization of a yeast chromosomal replicator". Nature. 282 (5734): 39–43. Bibcode:1979Natur.282...39S. doi:10.1038/282039a0. PMID 388229. S2CID 4326901.
Struhl, Kevin (1982-11-18). "Regulatory sites for his3 expression in yeast". Nature. 300 (5889): 285–286. doi:10.1038/300284a0. PMID 6755264. S2CID 4308484.
Struhl, Kevin (1985-10-01). "Negative control at a distance mediates catabolite repression in yeast". Nature. 317 (6040): 822–824. Bibcode:1985Natur.317..822S. doi:10.1038/317822a0. PMID 3903516. S2CID 2404872.
Hope, IA; Struhl, K (November 1988). "GCN4 protein, synthesized in vitro, binds to HIS3 regulatory sequences: implications for the general control of amino acid biosynthetic genes in yeast". Cell. 43 (1): 177–188. doi:10.1016/0092-8674(85)90022-4. PMID 3907851. S2CID 22627291.
Sellers, JW; Struhl, K (1989-09-07). "Changing fos oncoprotein to a DNA-binding protein with GCN4 dimerization specificity by swapping "leucine zippers"". Nature. 341 (6237): 74–76. doi:10.1038/341074a0. PMID 2505087. S2CID 4253004.
Ellenberger, Thomas E; Brandl, Christopher J; Struhl, Kevin; Harrison, Stephen C (1992-12-24). "The GCN4 basic-region-leucine zipper binds DNA as a dimer of uninterrupted a-helices: crystal structure of the protein-DNA complex". Cell. 71 (7): 1223–1237. doi:10.1016/S0092-8674(05)80070-4. PMID 1473154. S2CID 13548424.
Weiss, Michael A; Ellenberger, Thomas; Wobbe, C Richard; Lee, Jonathan P; Harrison, Stephen C; Struhl, Kevin (1990). "Folding transition in the DNA-binding domain of GCN4 on specific binding to DNA". Nature. 347 (6293): 575–578. Bibcode:1990Natur.347..575W. doi:10.1038/347575a0. PMID 2145515. S2CID 4366430.
Hope, IA; Struhl, K (1986-09-12). "Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast". Cell. 46 (6): 885–894. doi:10.1016/0092-8674(86)90070-X. PMID 3530496. S2CID 40730692.
Hope, IA; Mahadevan, S; Struhl, K (1988-06-16). "Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein". Nature. 333 (6174): 635–640. Bibcode:1988Natur.333..635H. doi:10.1038/333635a0. PMID 3287180. S2CID 2635634.
Struhl, Kevin (1987-09-11). "The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator are functionally homologous". Cell. 50 (6): 841–846. doi:10.1016/0092-8674(87)90511-3. PMID 3040261. S2CID 29588878.
Struhl, Kevin (1988-04-14). "The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast". Nature. 332 (6165): 649–650. Bibcode:1988Natur.332..649S. doi:10.1038/332649a0. PMID 3128739. S2CID 4350206.
Chatterjee, S; Struhl, K (1995-04-27). "Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain". Nature. 374 (6525): 820–822. doi:10.1038/374820a0. PMID 7723828. S2CID 4325887.
Kuras, L; Struhl, K (1999-06-10). "Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme". Nature. 399 (6736): 609–613. doi:10.1038/21239. PMID 10376605. S2CID 204993837.
Cormack, BP; Struhl, K (1992-05-15). "The TATA-binding protein is required for transcription by all three nuclear RNA polymerases in yeast cells". Cell. 69 (4): 685–696. doi:10.1016/0092-8674(92)90232-2. PMID 1586947. S2CID 7419671.
Cawley, S.; et al. (2004-02-20). "Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of non-coding RNAs". Cell. 116 (4): 499–509. doi:10.1016/S0092-8674(04)00127-8. PMID 14980218. S2CID 7793221.
Struhl, Kevin (February 2007). "Transcriptional noise and the fidelity of initiation by RNA polymerase II". Nature Structural & Molecular Biology. 14 (2): 103–105. doi:10.1038/nsmb0207-103. PMID 17277804. S2CID 29398526.
Moqtaderi, Zarmik; Bai, Yu; Poon, David; Weil, P Anthony; Struhl, Kevin (1996-09-12). "TBP-associated factors are not generally required for transcriptional activation in yeast". Nature. 383 (6596): 188–191. doi:10.1038/383188a0. PMID 8774887. S2CID 4351320.
Fan, Xiaochun; Chou, Danny M; Struhl, Kevin (2006-01-22). "Activator-specific recruitment of Mediator in vivo". Nature Structural & Molecular Biology. 13 (2): 117–120. doi:10.1038/nsmb1049. PMID 16429153. S2CID 20626638.
Wade, Joseph T; Hall, Daniel B; Struhl, Kevin (2004-12-23). "The transcription factor Ifh1 is a key regulator of yeast ribosomal protein genes". Nature. 432 (7020): 1054–1058. doi:10.1038/nature03175. PMID 15616568. S2CID 4334147.
Tzamarias, D; Struhl, K (1994-06-30). "Functional dissection of the yeast Cyc8-Tup1 transcriptional corepressor complex". Nature. 369 (6483): 758–761. doi:10.1038/369758a0. PMID 8008070. S2CID 4304771.
Proft, M; Struhl, K (2004-08-06). "A MAP kinase-mediated stress relief response that precedes and regulates the timing of transcriptional induction". Cell. 118 (3): 351–361. doi:10.1016/j.cell.2004.07.016. PMID 15294160. S2CID 2022911.
Wade, Joseph T; Roa, Daniel Castro; Grainger, David C; Hurd, Douglas; Busby, Stephen JW; Struhl, Kevin; Nudler, Evgeny (2006-08-06). "Extensive functional overlap between σ factors in Escherichia coli". Nature Structural & Molecular Biology. 13 (9): 806–814. doi:10.1038/nsmb1130. PMID 16892065. S2CID 19816595.
Zhang, Yong; Moqtaderi, Zarmik; Rattner, Barbara P; Euskirchen, Ghia; Snyder, Michael; Kadonaga, James T; Liu, X Shirley; Struhl, Kevin (2009-07-20). "Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo". Nature Structural & Molecular Biology. 16 (8): 847–852. doi:10.1038/nsmb.1636. PMC 2823114. PMID 19620965. S2CID 11805076.
Kadosh, David; Struhl, Kevin (1997-05-02). "Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters". Cell. 89 (3): 365–371. doi:10.1016/S0092-8674(00)80217-2. PMID 9150136. S2CID 15115179.

shouldersandknees.com

"Dr. Steven Struhl NYC Orthopedic Surgeon". Shoulders & Knees Steven Struhl MD.

si.com

vault.si.com

Horn, Houston (1965-03-08). "As Long As There's A Place To Go, Let It Snow". Sports Illustrated.

stanford.edu

med.stanford.edu

"Stanford University Alumni Association". Stanford Medicine.

wwlifetimeachievement.com

"Who's Who Lifetime Achievement". Who's Who Lifetime Achievement. 2018-09-13.

youtube.com

"YouTube - Stanford Medicine Alumni Association". December 7, 2023.