Klotho (biology) (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "Klotho (biology)" in English language version.

refsWebsite

Global rank English rank

62nih.gov

4^th place

35doi.org

2^nd place

9semanticscholar.org

11^th place

8^th place

6harvard.edu

18^th place

17^th place

3nature.com

234^th place

397^th place

2ensembl.org

1,626^th place

1,007^th place

2newatlas.com

5,636^th place

3,692^nd place

1genecards.org

low place

1cmj.org

low place

1handle.net

102^nd place

76^th place

cmj.org

Xiao NM, Zhang YM, Zheng Q, Gu J (May 2004). "Klotho is a serum factor related to human aging". Chinese Medical Journal. 117 (5): 742–747. PMID 15161545.^{[permanent dead link]}

doi.org

Matsumura Y, Aizawa H, Shiraki-Iida T, Nagai R, Kuro-o M, Nabeshima Y (January 1998). "Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein". Biochemical and Biophysical Research Communications. 242 (3): 626–630. doi:10.1006/bbrc.1997.8019. PMID 9464267.
Dolegowska K, Marchelek-Mysliwiec M, Nowosiad-Magda M, Slawinski M, Dolegowska B (June 2019). "FGF19 subfamily members: FGF19 and FGF21". Journal of Physiology and Biochemistry. 75 (2): 229–240. doi:10.1007/s13105-019-00675-7. PMC 6611749. PMID 30927227.
Kuro-O M (January 2019). "The Klotho proteins in health and disease". Nature Reviews. Nephrology. 15 (1): 27–44. doi:10.1038/s41581-018-0078-3. PMID 30455427. S2CID 53872296.
Lim K, Halim A, Lu TS, Ashworth A, Chong I (September 2019). "Klotho: A Major Shareholder in Vascular Aging Enterprises". International Journal of Molecular Sciences. 20 (18): E4637. doi:10.3390/ijms20184637. PMC 6770519. PMID 31546756.
Hanson K, Fisher K, Hooper NM (June 2021). "Exploiting the neuroprotective effects of α-klotho to tackle ageing- and neurodegeneration-related cognitive dysfunction". Neuronal Signaling. 5 (2): NS20200101. doi:10.1042/NS20200101. PMC 8204227. PMID 34194816.
Kurt B, Kurtz A (March 2015). "Plasticity of renal endocrine function". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 308 (6): R455–R466. doi:10.1152/ajpregu.00568.2013. PMID 25608752. S2CID 37452911.
Buendía P, Ramírez R, Aljama P, Carracedo J (2016). "Klotho Prevents Translocation of NFκB". Klotho. Vitamins & Hormones. Vol. 101. pp. 119–150. doi:10.1016/bs.vh.2016.02.005. ISBN 9780128048191. PMID 27125740.
Martín-González C, González-Reimers E, Quintero-Platt G, Martínez-Riera A, Santolaria-Fernández F (May 2019). "Soluble α-Klotho in Liver Cirrhosis and Alcoholism". Alcohol and Alcoholism. 54 (3): 204–208. doi:10.1093/alcalc/agz019. PMC 6731336. PMID 30860544.
Schumann G, Liu C, O'Reilly P, Gao H, Song P, Xu B, et al. (December 2016). "KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference". Proceedings of the National Academy of Sciences of the United States of America. 113 (50): 14372–14377. Bibcode:2016PNAS..11314372S. doi:10.1073/pnas.1611243113. PMC 5167198. PMID 27911795.
Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, et al. (September 2005). "Suppression of aging in mice by the hormone Klotho". Science. 309 (5742): 1829–1833. Bibcode:2005Sci...309.1829K. doi:10.1126/science.1112766. PMC 2536606. PMID 16123266.
Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, et al. (November 1997). "Mutation of the mouse klotho gene leads to a syndrome resembling ageing". Nature. 390 (6655): 45–51. Bibcode:1997Natur.390...45K. doi:10.1038/36285. PMID 9363890. S2CID 4428141.
Arking DE, Krebsova A, Macek M, Macek M, Arking A, Mian IS, et al. (January 2002). "Association of human aging with a functional variant of klotho". Proceedings of the National Academy of Sciences of the United States of America. 99 (2): 856–861. Bibcode:2002PNAS...99..856A. doi:10.1073/pnas.022484299. PMC 117395. PMID 11792841.
Helsten T, Schwaederle M, Kurzrock R (September 2015). "Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications". Cancer and Metastasis Reviews. 34 (3): 479–496. doi:10.1007/s10555-015-9579-8. PMC 4573649. PMID 26224133.
Talukdar S, Owen BM, Song P, Hernandez G, Zhang Y, Zhou Y, et al. (February 2016). "FGF21 Regulates Sweet and Alcohol Preference". Cell Metabolism. 23 (2): 344–349. doi:10.1016/j.cmet.2015.12.008. PMC 4749404. PMID 26724861.
Flippo KH, Potthoff MJ (March 2021). "Metabolic Messengers: FGF21". Nature Metabolism. 3 (3): 309–317. doi:10.1038/s42255-021-00354-2. PMC 8620721. PMID 33758421.
Huang CL (May 2010). "Regulation of ion channels by secreted Klotho: mechanisms and implications". Kidney International. 77 (10): 855–860. doi:10.1038/ki.2010.73. PMID 20375979.
van Goor MK, Hoenderop JG, van der Wijst J (June 2017). "TRP channels in calcium homeostasis: from hormonal control to structure-function relationship of TRPV5 and TRPV6". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1864 (6): 883–893. doi:10.1016/j.bbamcr.2016.11.027. PMID 27913205.
Wolf MT, An SW, Nie M, Bal MS, Huang CL (December 2014). "Klotho up-regulates renal calcium channel transient receptor potential vanilloid 5 (TRPV5) by intra- and extracellular N-glycosylation-dependent mechanisms". The Journal of Biological Chemistry. 289 (52): 35849–35857. doi:10.1074/jbc.M114.616649. PMC 4276853. PMID 25378396.
Saghiv MS, Sira DB, Goldhammer E, Sagiv M (2017). "The effects of aerobic and anaerobic exercises on circulating soluble-Klotho and IGF-I in young and elderly adults and in CAD patients". Journal of Circulating Biomarkers. 6: 1849454417733388. doi:10.1177/1849454417733388. PMC 5644364. PMID 29081845.
Olejnik A, Franczak A, Krzywonos-Zawadzka A, Kałużna-Oleksy M, Bil-Lula I (2018). "The Biological Role of Klotho Protein in the Development of Cardiovascular Diseases". BioMed Research International. 2018: 5171945. doi:10.1155/2018/5171945. PMC 6323445. PMID 30671457.
Torbus-Paluszczak M, Bartman W, Adamczyk-Sowa M (October 2018). "Klotho protein in neurodegenerative disorders". Neurological Sciences. 39 (10): 1677–1682. doi:10.1007/s10072-018-3496-x. PMC 6154120. PMID 30062646.
Vo HT, Laszczyk AM, King GD (August 2018). "Klotho, the Key to Healthy Brain Aging?". Brain Plasticity. 3 (2): 183–194. doi:10.3233/BPL-170057. PMC 6091049. PMID 30151342.
Tozer L (4 July 2023). "Anti-ageing protein injection boosts monkeys' memories". Nature. 619 (7969): 234. Bibcode:2023Natur.619..234T. doi:10.1038/d41586-023-02214-3. PMID 37402904. S2CID 259334272.
Castner SA, Gupta S, Wang D, Moreno AJ, Park C, Chen C, et al. (July 2023). "Longevity factor klotho enhances cognition in aged nonhuman primates". Nature Aging. 3 (8): 931–937. doi:10.1038/s43587-023-00441-x. PMC 10432271. PMID 37400721. S2CID 259322607.
Zhou H, Pu S, Zhou H, Guo Y (2021). "Klotho as Potential Autophagy Regulator and Therapeutic Target". Frontiers in Pharmacology. 12: 755366. doi:10.3389/fphar.2021.755366. PMC 8560683. PMID 34737707.
Adhikari BR, Uehara O, Matsuoka H, Takai R, Harada F, Utsunomiya M, et al. (September 2017). "Immunohistochemical evaluation of Klotho and DNA methyltransferase 3a in oral squamous cell carcinomas". Medical Molecular Morphology. 50 (3): 155–160. doi:10.1007/s00795-017-0156-9. PMID 28303350. S2CID 22810635.
Paroni G, Panza F, De Cosmo S, Greco A, Seripa D, Mazzoccoli G (March 2019). "Klotho at the Edge of Alzheimer's Disease and Senile Depression". Molecular Neurobiology. 56 (3): 1908–1920. doi:10.1007/s12035-018-1200-z. PMID 29978424. S2CID 49567009.
Lehrer S, Rheinstein PH (2020). "Alignment of Alzheimer's disease amyloid β-peptide and klotho". World Academy of Sciences Journal. 2 (6): 1. doi:10.3892/wasj.2020.68. PMC 7521834. PMID 32999998.
Veronesi F, Borsari V, Cherubini A, Fini M (October 2021). "Association of Klotho with physical performance and frailty in middle-aged and older adults: A systematic review". Experimental Gerontology. 154: 111518. doi:10.1016/j.exger.2021.111518. PMID 34407459. S2CID 237011996.
Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, et al. (May 2014). "Life extension factor klotho enhances cognition". Cell Reports. 7 (4): 1065–1076. doi:10.1016/j.celrep.2014.03.076. PMC 4176932. PMID 24813892.
Kuro-o M (October 2009). "Klotho and aging". Biochimica et Biophysica Acta (BBA) - General Subjects. 1790 (10): 1049–1058. doi:10.1016/j.bbagen.2009.02.005. PMC 2743784. PMID 19230844.
Medici D, Razzaque MS, Deluca S, Rector TL, Hou B, Kang K, et al. (August 2008). "FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis". The Journal of Cell Biology. 182 (3): 459–465. doi:10.1083/jcb.200803024. PMC 2500132. PMID 18678710.
Tsujikawa H, Kurotaki Y, Fujimori T, Fukuda K, Nabeshima Y (December 2003). "Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system". Molecular Endocrinology. 17 (12): 2393–2403. doi:10.1210/me.2003-0048. hdl:2433/145275. PMID 14528024.
Imura A, Tsuji Y, Murata M, Maeda R, Kubota K, Iwano A, et al. (June 2007). "alpha-Klotho as a regulator of calcium homeostasis". Science. 316 (5831): 1615–1618. Bibcode:2007Sci...316.1615I. doi:10.1126/science.1135901. PMID 17569864. S2CID 40529168.
Liu H, Fergusson MM, Castilho RM, Liu J, Cao L, Chen J, et al. (August 2007). "Augmented Wnt signaling in a mammalian model of accelerated aging". Science. 317 (5839): 803–806. doi:10.1038/ki.2010.73. PMID 17690294.

ensembl.org

May2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000133116 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000058488 – Ensembl, May 2017

genecards.org

"Klotho Beta". Retrieved 12 September 2023.

handle.net

hdl.handle.net

Tsujikawa H, Kurotaki Y, Fujimori T, Fukuda K, Nabeshima Y (December 2003). "Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system". Molecular Endocrinology. 17 (12): 2393–2403. doi:10.1210/me.2003-0048. hdl:2433/145275. PMID 14528024.

harvard.edu

ui.adsabs.harvard.edu

Schumann G, Liu C, O'Reilly P, Gao H, Song P, Xu B, et al. (December 2016). "KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference". Proceedings of the National Academy of Sciences of the United States of America. 113 (50): 14372–14377. Bibcode:2016PNAS..11314372S. doi:10.1073/pnas.1611243113. PMC 5167198. PMID 27911795.
Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, et al. (September 2005). "Suppression of aging in mice by the hormone Klotho". Science. 309 (5742): 1829–1833. Bibcode:2005Sci...309.1829K. doi:10.1126/science.1112766. PMC 2536606. PMID 16123266.
Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, et al. (November 1997). "Mutation of the mouse klotho gene leads to a syndrome resembling ageing". Nature. 390 (6655): 45–51. Bibcode:1997Natur.390...45K. doi:10.1038/36285. PMID 9363890. S2CID 4428141.
Arking DE, Krebsova A, Macek M, Macek M, Arking A, Mian IS, et al. (January 2002). "Association of human aging with a functional variant of klotho". Proceedings of the National Academy of Sciences of the United States of America. 99 (2): 856–861. Bibcode:2002PNAS...99..856A. doi:10.1073/pnas.022484299. PMC 117395. PMID 11792841.
Tozer L (4 July 2023). "Anti-ageing protein injection boosts monkeys' memories". Nature. 619 (7969): 234. Bibcode:2023Natur.619..234T. doi:10.1038/d41586-023-02214-3. PMID 37402904. S2CID 259334272.
Imura A, Tsuji Y, Murata M, Maeda R, Kubota K, Iwano A, et al. (June 2007). "alpha-Klotho as a regulator of calcium homeostasis". Science. 316 (5831): 1615–1618. Bibcode:2007Sci...316.1615I. doi:10.1126/science.1135901. PMID 17569864. S2CID 40529168.

nature.com

"Klotho Beta". Retrieved 30 October 2024.
"Klotho Beta". Retrieved 30 October 2024.
Tozer L (4 July 2023). "Anti-ageing protein injection boosts monkeys' memories". Nature. 619 (7969): 234. Bibcode:2023Natur.619..234T. doi:10.1038/d41586-023-02214-3. PMID 37402904. S2CID 259334272.

newatlas.com

Irving M (2021-12-10). ""Young blood" particles that help old mice fight aging identified". New Atlas. Retrieved 2021-12-11.
Irving M (2022-03-16). "Senolytic drugs boost protein that protects against effects of aging". New Atlas. Retrieved 2022-03-16.

nih.gov

pubmed.ncbi.nlm.nih.gov

Matsumura Y, Aizawa H, Shiraki-Iida T, Nagai R, Kuro-o M, Nabeshima Y (January 1998). "Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein". Biochemical and Biophysical Research Communications. 242 (3): 626–630. doi:10.1006/bbrc.1997.8019. PMID 9464267.
Dolegowska K, Marchelek-Mysliwiec M, Nowosiad-Magda M, Slawinski M, Dolegowska B (June 2019). "FGF19 subfamily members: FGF19 and FGF21". Journal of Physiology and Biochemistry. 75 (2): 229–240. doi:10.1007/s13105-019-00675-7. PMC 6611749. PMID 30927227.
Kuro-O M (January 2019). "The Klotho proteins in health and disease". Nature Reviews. Nephrology. 15 (1): 27–44. doi:10.1038/s41581-018-0078-3. PMID 30455427. S2CID 53872296.
Lim K, Halim A, Lu TS, Ashworth A, Chong I (September 2019). "Klotho: A Major Shareholder in Vascular Aging Enterprises". International Journal of Molecular Sciences. 20 (18): E4637. doi:10.3390/ijms20184637. PMC 6770519. PMID 31546756.
Hanson K, Fisher K, Hooper NM (June 2021). "Exploiting the neuroprotective effects of α-klotho to tackle ageing- and neurodegeneration-related cognitive dysfunction". Neuronal Signaling. 5 (2): NS20200101. doi:10.1042/NS20200101. PMC 8204227. PMID 34194816.
Kurt B, Kurtz A (March 2015). "Plasticity of renal endocrine function". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 308 (6): R455–R466. doi:10.1152/ajpregu.00568.2013. PMID 25608752. S2CID 37452911.
Buendía P, Ramírez R, Aljama P, Carracedo J (2016). "Klotho Prevents Translocation of NFκB". Klotho. Vitamins & Hormones. Vol. 101. pp. 119–150. doi:10.1016/bs.vh.2016.02.005. ISBN 9780128048191. PMID 27125740.
Martín-González C, González-Reimers E, Quintero-Platt G, Martínez-Riera A, Santolaria-Fernández F (May 2019). "Soluble α-Klotho in Liver Cirrhosis and Alcoholism". Alcohol and Alcoholism. 54 (3): 204–208. doi:10.1093/alcalc/agz019. PMC 6731336. PMID 30860544.
Schumann G, Liu C, O'Reilly P, Gao H, Song P, Xu B, et al. (December 2016). "KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference". Proceedings of the National Academy of Sciences of the United States of America. 113 (50): 14372–14377. Bibcode:2016PNAS..11314372S. doi:10.1073/pnas.1611243113. PMC 5167198. PMID 27911795.
Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, et al. (September 2005). "Suppression of aging in mice by the hormone Klotho". Science. 309 (5742): 1829–1833. Bibcode:2005Sci...309.1829K. doi:10.1126/science.1112766. PMC 2536606. PMID 16123266.
"Klotho Beta". Retrieved 30 October 2024.
Baranowska B, Kochanowski J (September 2020). "The metabolic, neuroprotective cardioprotective and antitumor effects of the Klotho protein". Neuro Endocrinology Letters. 41 (2): 69–75. PMID 33185993.
Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, et al. (November 1997). "Mutation of the mouse klotho gene leads to a syndrome resembling ageing". Nature. 390 (6655): 45–51. Bibcode:1997Natur.390...45K. doi:10.1038/36285. PMID 9363890. S2CID 4428141.
Arking DE, Krebsova A, Macek M, Macek M, Arking A, Mian IS, et al. (January 2002). "Association of human aging with a functional variant of klotho". Proceedings of the National Academy of Sciences of the United States of America. 99 (2): 856–861. Bibcode:2002PNAS...99..856A. doi:10.1073/pnas.022484299. PMC 117395. PMID 11792841.
Xiao NM, Zhang YM, Zheng Q, Gu J (May 2004). "Klotho is a serum factor related to human aging". Chinese Medical Journal. 117 (5): 742–747. PMID 15161545.^{[permanent dead link]}
Helsten T, Schwaederle M, Kurzrock R (September 2015). "Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications". Cancer and Metastasis Reviews. 34 (3): 479–496. doi:10.1007/s10555-015-9579-8. PMC 4573649. PMID 26224133.
Talukdar S, Owen BM, Song P, Hernandez G, Zhang Y, Zhou Y, et al. (February 2016). "FGF21 Regulates Sweet and Alcohol Preference". Cell Metabolism. 23 (2): 344–349. doi:10.1016/j.cmet.2015.12.008. PMC 4749404. PMID 26724861.
Flippo KH, Potthoff MJ (March 2021). "Metabolic Messengers: FGF21". Nature Metabolism. 3 (3): 309–317. doi:10.1038/s42255-021-00354-2. PMC 8620721. PMID 33758421.
Huang CL (May 2010). "Regulation of ion channels by secreted Klotho: mechanisms and implications". Kidney International. 77 (10): 855–860. doi:10.1038/ki.2010.73. PMID 20375979.
van Goor MK, Hoenderop JG, van der Wijst J (June 2017). "TRP channels in calcium homeostasis: from hormonal control to structure-function relationship of TRPV5 and TRPV6". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1864 (6): 883–893. doi:10.1016/j.bbamcr.2016.11.027. PMID 27913205.
Wolf MT, An SW, Nie M, Bal MS, Huang CL (December 2014). "Klotho up-regulates renal calcium channel transient receptor potential vanilloid 5 (TRPV5) by intra- and extracellular N-glycosylation-dependent mechanisms". The Journal of Biological Chemistry. 289 (52): 35849–35857. doi:10.1074/jbc.M114.616649. PMC 4276853. PMID 25378396.
Saghiv MS, Sira DB, Goldhammer E, Sagiv M (2017). "The effects of aerobic and anaerobic exercises on circulating soluble-Klotho and IGF-I in young and elderly adults and in CAD patients". Journal of Circulating Biomarkers. 6: 1849454417733388. doi:10.1177/1849454417733388. PMC 5644364. PMID 29081845.
Olejnik A, Franczak A, Krzywonos-Zawadzka A, Kałużna-Oleksy M, Bil-Lula I (2018). "The Biological Role of Klotho Protein in the Development of Cardiovascular Diseases". BioMed Research International. 2018: 5171945. doi:10.1155/2018/5171945. PMC 6323445. PMID 30671457.
Torbus-Paluszczak M, Bartman W, Adamczyk-Sowa M (October 2018). "Klotho protein in neurodegenerative disorders". Neurological Sciences. 39 (10): 1677–1682. doi:10.1007/s10072-018-3496-x. PMC 6154120. PMID 30062646.
Vo HT, Laszczyk AM, King GD (August 2018). "Klotho, the Key to Healthy Brain Aging?". Brain Plasticity. 3 (2): 183–194. doi:10.3233/BPL-170057. PMC 6091049. PMID 30151342.
Tozer L (4 July 2023). "Anti-ageing protein injection boosts monkeys' memories". Nature. 619 (7969): 234. Bibcode:2023Natur.619..234T. doi:10.1038/d41586-023-02214-3. PMID 37402904. S2CID 259334272.
Castner SA, Gupta S, Wang D, Moreno AJ, Park C, Chen C, et al. (July 2023). "Longevity factor klotho enhances cognition in aged nonhuman primates". Nature Aging. 3 (8): 931–937. doi:10.1038/s43587-023-00441-x. PMC 10432271. PMID 37400721. S2CID 259322607.
Zhou H, Pu S, Zhou H, Guo Y (2021). "Klotho as Potential Autophagy Regulator and Therapeutic Target". Frontiers in Pharmacology. 12: 755366. doi:10.3389/fphar.2021.755366. PMC 8560683. PMID 34737707.
Adhikari BR, Uehara O, Matsuoka H, Takai R, Harada F, Utsunomiya M, et al. (September 2017). "Immunohistochemical evaluation of Klotho and DNA methyltransferase 3a in oral squamous cell carcinomas". Medical Molecular Morphology. 50 (3): 155–160. doi:10.1007/s00795-017-0156-9. PMID 28303350. S2CID 22810635.
Paroni G, Panza F, De Cosmo S, Greco A, Seripa D, Mazzoccoli G (March 2019). "Klotho at the Edge of Alzheimer's Disease and Senile Depression". Molecular Neurobiology. 56 (3): 1908–1920. doi:10.1007/s12035-018-1200-z. PMID 29978424. S2CID 49567009.
Lehrer S, Rheinstein PH (2020). "Alignment of Alzheimer's disease amyloid β-peptide and klotho". World Academy of Sciences Journal. 2 (6): 1. doi:10.3892/wasj.2020.68. PMC 7521834. PMID 32999998.
Veronesi F, Borsari V, Cherubini A, Fini M (October 2021). "Association of Klotho with physical performance and frailty in middle-aged and older adults: A systematic review". Experimental Gerontology. 154: 111518. doi:10.1016/j.exger.2021.111518. PMID 34407459. S2CID 237011996.
Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, et al. (May 2014). "Life extension factor klotho enhances cognition". Cell Reports. 7 (4): 1065–1076. doi:10.1016/j.celrep.2014.03.076. PMC 4176932. PMID 24813892.
Kuro-o M (October 2009). "Klotho and aging". Biochimica et Biophysica Acta (BBA) - General Subjects. 1790 (10): 1049–1058. doi:10.1016/j.bbagen.2009.02.005. PMC 2743784. PMID 19230844.
Medici D, Razzaque MS, Deluca S, Rector TL, Hou B, Kang K, et al. (August 2008). "FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis". The Journal of Cell Biology. 182 (3): 459–465. doi:10.1083/jcb.200803024. PMC 2500132. PMID 18678710.
Tsujikawa H, Kurotaki Y, Fujimori T, Fukuda K, Nabeshima Y (December 2003). "Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system". Molecular Endocrinology. 17 (12): 2393–2403. doi:10.1210/me.2003-0048. hdl:2433/145275. PMID 14528024.
Imura A, Tsuji Y, Murata M, Maeda R, Kubota K, Iwano A, et al. (June 2007). "alpha-Klotho as a regulator of calcium homeostasis". Science. 316 (5831): 1615–1618. Bibcode:2007Sci...316.1615I. doi:10.1126/science.1135901. PMID 17569864. S2CID 40529168.
Liu H, Fergusson MM, Castilho RM, Liu J, Cao L, Chen J, et al. (August 2007). "Augmented Wnt signaling in a mammalian model of accelerated aging". Science. 317 (5839): 803–806. doi:10.1038/ki.2010.73. PMID 17690294.

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Dolegowska K, Marchelek-Mysliwiec M, Nowosiad-Magda M, Slawinski M, Dolegowska B (June 2019). "FGF19 subfamily members: FGF19 and FGF21". Journal of Physiology and Biochemistry. 75 (2): 229–240. doi:10.1007/s13105-019-00675-7. PMC 6611749. PMID 30927227.
Lim K, Halim A, Lu TS, Ashworth A, Chong I (September 2019). "Klotho: A Major Shareholder in Vascular Aging Enterprises". International Journal of Molecular Sciences. 20 (18): E4637. doi:10.3390/ijms20184637. PMC 6770519. PMID 31546756.
Hanson K, Fisher K, Hooper NM (June 2021). "Exploiting the neuroprotective effects of α-klotho to tackle ageing- and neurodegeneration-related cognitive dysfunction". Neuronal Signaling. 5 (2): NS20200101. doi:10.1042/NS20200101. PMC 8204227. PMID 34194816.
Martín-González C, González-Reimers E, Quintero-Platt G, Martínez-Riera A, Santolaria-Fernández F (May 2019). "Soluble α-Klotho in Liver Cirrhosis and Alcoholism". Alcohol and Alcoholism. 54 (3): 204–208. doi:10.1093/alcalc/agz019. PMC 6731336. PMID 30860544.
"Entrez Gene: klotho".
Schumann G, Liu C, O'Reilly P, Gao H, Song P, Xu B, et al. (December 2016). "KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference". Proceedings of the National Academy of Sciences of the United States of America. 113 (50): 14372–14377. Bibcode:2016PNAS..11314372S. doi:10.1073/pnas.1611243113. PMC 5167198. PMID 27911795.
Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, et al. (September 2005). "Suppression of aging in mice by the hormone Klotho". Science. 309 (5742): 1829–1833. Bibcode:2005Sci...309.1829K. doi:10.1126/science.1112766. PMC 2536606. PMID 16123266.
Arking DE, Krebsova A, Macek M, Macek M, Arking A, Mian IS, et al. (January 2002). "Association of human aging with a functional variant of klotho". Proceedings of the National Academy of Sciences of the United States of America. 99 (2): 856–861. Bibcode:2002PNAS...99..856A. doi:10.1073/pnas.022484299. PMC 117395. PMID 11792841.
Helsten T, Schwaederle M, Kurzrock R (September 2015). "Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications". Cancer and Metastasis Reviews. 34 (3): 479–496. doi:10.1007/s10555-015-9579-8. PMC 4573649. PMID 26224133.
Talukdar S, Owen BM, Song P, Hernandez G, Zhang Y, Zhou Y, et al. (February 2016). "FGF21 Regulates Sweet and Alcohol Preference". Cell Metabolism. 23 (2): 344–349. doi:10.1016/j.cmet.2015.12.008. PMC 4749404. PMID 26724861.
Flippo KH, Potthoff MJ (March 2021). "Metabolic Messengers: FGF21". Nature Metabolism. 3 (3): 309–317. doi:10.1038/s42255-021-00354-2. PMC 8620721. PMID 33758421.
Wolf MT, An SW, Nie M, Bal MS, Huang CL (December 2014). "Klotho up-regulates renal calcium channel transient receptor potential vanilloid 5 (TRPV5) by intra- and extracellular N-glycosylation-dependent mechanisms". The Journal of Biological Chemistry. 289 (52): 35849–35857. doi:10.1074/jbc.M114.616649. PMC 4276853. PMID 25378396.
Saghiv MS, Sira DB, Goldhammer E, Sagiv M (2017). "The effects of aerobic and anaerobic exercises on circulating soluble-Klotho and IGF-I in young and elderly adults and in CAD patients". Journal of Circulating Biomarkers. 6: 1849454417733388. doi:10.1177/1849454417733388. PMC 5644364. PMID 29081845.
Olejnik A, Franczak A, Krzywonos-Zawadzka A, Kałużna-Oleksy M, Bil-Lula I (2018). "The Biological Role of Klotho Protein in the Development of Cardiovascular Diseases". BioMed Research International. 2018: 5171945. doi:10.1155/2018/5171945. PMC 6323445. PMID 30671457.
Torbus-Paluszczak M, Bartman W, Adamczyk-Sowa M (October 2018). "Klotho protein in neurodegenerative disorders". Neurological Sciences. 39 (10): 1677–1682. doi:10.1007/s10072-018-3496-x. PMC 6154120. PMID 30062646.
Vo HT, Laszczyk AM, King GD (August 2018). "Klotho, the Key to Healthy Brain Aging?". Brain Plasticity. 3 (2): 183–194. doi:10.3233/BPL-170057. PMC 6091049. PMID 30151342.
Castner SA, Gupta S, Wang D, Moreno AJ, Park C, Chen C, et al. (July 2023). "Longevity factor klotho enhances cognition in aged nonhuman primates". Nature Aging. 3 (8): 931–937. doi:10.1038/s43587-023-00441-x. PMC 10432271. PMID 37400721. S2CID 259322607.
Zhou H, Pu S, Zhou H, Guo Y (2021). "Klotho as Potential Autophagy Regulator and Therapeutic Target". Frontiers in Pharmacology. 12: 755366. doi:10.3389/fphar.2021.755366. PMC 8560683. PMID 34737707.
Lehrer S, Rheinstein PH (2020). "Alignment of Alzheimer's disease amyloid β-peptide and klotho". World Academy of Sciences Journal. 2 (6): 1. doi:10.3892/wasj.2020.68. PMC 7521834. PMID 32999998.
Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, et al. (May 2014). "Life extension factor klotho enhances cognition". Cell Reports. 7 (4): 1065–1076. doi:10.1016/j.celrep.2014.03.076. PMC 4176932. PMID 24813892.
Kuro-o M (October 2009). "Klotho and aging". Biochimica et Biophysica Acta (BBA) - General Subjects. 1790 (10): 1049–1058. doi:10.1016/j.bbagen.2009.02.005. PMC 2743784. PMID 19230844.
Medici D, Razzaque MS, Deluca S, Rector TL, Hou B, Kang K, et al. (August 2008). "FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis". The Journal of Cell Biology. 182 (3): 459–465. doi:10.1083/jcb.200803024. PMC 2500132. PMID 18678710.

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Kuro-O M (January 2019). "The Klotho proteins in health and disease". Nature Reviews. Nephrology. 15 (1): 27–44. doi:10.1038/s41581-018-0078-3. PMID 30455427. S2CID 53872296.
Kurt B, Kurtz A (March 2015). "Plasticity of renal endocrine function". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 308 (6): R455–R466. doi:10.1152/ajpregu.00568.2013. PMID 25608752. S2CID 37452911.
Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, et al. (November 1997). "Mutation of the mouse klotho gene leads to a syndrome resembling ageing". Nature. 390 (6655): 45–51. Bibcode:1997Natur.390...45K. doi:10.1038/36285. PMID 9363890. S2CID 4428141.
Tozer L (4 July 2023). "Anti-ageing protein injection boosts monkeys' memories". Nature. 619 (7969): 234. Bibcode:2023Natur.619..234T. doi:10.1038/d41586-023-02214-3. PMID 37402904. S2CID 259334272.
Castner SA, Gupta S, Wang D, Moreno AJ, Park C, Chen C, et al. (July 2023). "Longevity factor klotho enhances cognition in aged nonhuman primates". Nature Aging. 3 (8): 931–937. doi:10.1038/s43587-023-00441-x. PMC 10432271. PMID 37400721. S2CID 259322607.
Adhikari BR, Uehara O, Matsuoka H, Takai R, Harada F, Utsunomiya M, et al. (September 2017). "Immunohistochemical evaluation of Klotho and DNA methyltransferase 3a in oral squamous cell carcinomas". Medical Molecular Morphology. 50 (3): 155–160. doi:10.1007/s00795-017-0156-9. PMID 28303350. S2CID 22810635.
Paroni G, Panza F, De Cosmo S, Greco A, Seripa D, Mazzoccoli G (March 2019). "Klotho at the Edge of Alzheimer's Disease and Senile Depression". Molecular Neurobiology. 56 (3): 1908–1920. doi:10.1007/s12035-018-1200-z. PMID 29978424. S2CID 49567009.
Veronesi F, Borsari V, Cherubini A, Fini M (October 2021). "Association of Klotho with physical performance and frailty in middle-aged and older adults: A systematic review". Experimental Gerontology. 154: 111518. doi:10.1016/j.exger.2021.111518. PMID 34407459. S2CID 237011996.
Imura A, Tsuji Y, Murata M, Maeda R, Kubota K, Iwano A, et al. (June 2007). "alpha-Klotho as a regulator of calcium homeostasis". Science. 316 (5831): 1615–1618. Bibcode:2007Sci...316.1615I. doi:10.1126/science.1135901. PMID 17569864. S2CID 40529168.