References analysis of the Wikipedia article "Leucyl/cystinyl aminopeptidase" in the English version

doi.org

Keller SR (June 2004). "Role of the insulin-regulated aminopeptidase IRAP in insulin action and diabetes". Biological & Pharmaceutical Bulletin. 27 (6): 761–764. doi:10.1248/bpb.27.761. PMID 15187412.

Herbst JJ, Ross SA, Scott HM, Bobin SA, Morris NJ, Lienhard GE, et al. (April 1997). "Insulin stimulates cell surface aminopeptidase activity toward vasopressin in adipocytes". The American Journal of Physiology. 272 (4 Pt 1): E600 – E606. doi:10.1152/ajpendo.1997.272.4.e600. PMID 9142880.

Bernstein HG, Müller S, Dobrowolny H, Wolke C, Lendeckel U, Bukowska A, et al. (August 2017). "Insulin-regulated aminopeptidase immunoreactivity is abundantly present in human hypothalamus and posterior pituitary gland, with reduced expression in paraventricular and suprachiasmatic neurons in chronic schizophrenia". European Archives of Psychiatry and Clinical Neuroscience. 267 (5): 427–443. doi:10.1007/s00406-016-0757-7. PMID 28035472.

Yeatman HR, Albiston AL, Burns P, Chai SY (December 2016). "Forebrain neurone-specific deletion of insulin-regulated aminopeptidase causes age related deficits in memory". Neurobiology of Learning and Memory. 136: 174–182. doi:10.1016/j.nlm.2016.09.017. PMID 27713012.

Royea J, Hamel E (October 2020). "Brain angiotensin II and angiotensin IV receptors as potential Alzheimer's disease therapeutic targets". GeroScience. 42 (5): 1237–1256. doi:10.1007/s11357-020-00231-y. PMC 7525853. PMID 32700176.

Sun X, Deng Y, Fu X, Wang S, Duan R, Zhang Y (November 2021). "AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway". Brain Sciences. 11 (11): 1487. doi:10.3390/brainsci11111487. PMC 8615599. PMID 34827486.

Demaegdt H, Gard P, De Backer JP, Lukaszuk A, Szemenyei E, Tóth G, et al. (June 2011). "Binding of "AT4 receptor" ligands to insulin regulated aminopeptidase (IRAP) in intact Chinese hamster ovary cells" (PDF). Molecular and Cellular Endocrinology. 339 (1–2): 34–44. doi:10.1016/j.mce.2011.03.005. PMID 21457753.

Nikolaou A, Van den Eynde I, Tourwé D, Vauquelin G, Tóth G, Mallareddy JR, et al. (February 2013). "[3H]IVDE77, a novel radioligand with high affinity and selectivity for the insulin-regulated aminopeptidase". European Journal of Pharmacology. 702 (1–3): 93–102. doi:10.1016/j.ejphar.2013.01.026. PMID 23376157.

Wright JW, Kawas LH, Harding JW (February 2015). "The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases". Progress in Neurobiology. 125: 26–46. doi:10.1016/j.pneurobio.2014.11.004. PMID 25455861.

El-Hawli A, Qaradakhi T, Hayes A, Rybalka E, Smith R, Caprnda M, et al. (February 2017). "IRAP inhibition using HFI419 prevents moderate to severe acetylcholine mediated vasoconstriction in a rabbit model". Biomedicine & Pharmacotherapy. 86: 23–26. doi:10.1016/j.biopha.2016.11.142. PMID 27936390.

Saveanu L, Carroll O, Weimershaus M, Guermonprez P, Firat E, Lindo V, et al. (July 2009). "IRAP identifies an endosomal compartment required for MHC class I cross-presentation". Science. 325 (5937): 213–217. Bibcode:2009Sci...325..213S. doi:10.1126/science.1172845. PMID 19498108.

Baldari CT, Onnis A (2021). IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses. Faculty Opinions Recommendation (Report). doi:10.3410/f.738064950.793586214.

Babdor J, Descamps D, Adiko AC, Tohmé M, Maschalidi S, Evnouchidou I, et al. (May 2017). "IRAP⁺ endosomes restrict TLR9 activation and signaling". Nature Immunology. 18 (5): 509–518. doi:10.1038/ni.3711. PMID 28319098.

Weimershaus M, Carvalho C, Rignault R, Waeckel-Enee E, Dussiot M, van Endert P, et al. (June 2023). "Mast cell-mediated inflammation relies on insulin-regulated aminopeptidase controlling cytokine export from the Golgi". The Journal of Allergy and Clinical Immunology. 151 (6): 1595–1608.e6. bioRxiv 10.1101/2022.01.21.477149. doi:10.1016/j.jaci.2023.01.014. PMID 36708814.

Venema WJ, Hiddingh S, van Loosdregt J, Bowes J, Balliu B, de Boer JH, et al. (January 2024). "A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs". Cell Genomics. 4 (1): 100460. bioRxiv 10.1101/2023.03.03.530973. doi:10.1016/j.xgen.2023.100460. PMID 38190099.

Mulder N (2020). Faculty Opinions recommendation of The mutational constraint spectrum quantified from variation in 141,456 humans. doi:10.3410/f.738024093.793575805.

Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, et al. (Wellcome Trust Case Control Consortium) (November 2007). "Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants". Nature Genetics. 39 (11): 1329–37. doi:10.1038/ng.2007.17. PMC 2680141. PMID 17952073.

Cheng H, Li Y, Zuo XB, Tang HY, Tang XF, Gao JP, et al. (February 2014). "Identification of a missense variant in LNPEP that confers psoriasis risk". The Journal of Investigative Dermatology. 134 (2): 359–365. doi:10.1038/jid.2013.317. PMID 23897274.

Shibata K, Kajiyama H, Ino K, Nawa A, Nomura S, Mizutani S, et al. (January 2007). "P-LAP/IRAP-induced cell proliferation and glucose uptake in endometrial carcinoma cells via insulin receptor signaling". BMC Cancer. 7 (1): 15. doi:10.1186/1471-2407-7-15. PMC 1781462. PMID 17233921.

Keller SR, Scott HM, Mastick CC, Aebersold R, Lienhard GE (October 1995). "Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles". The Journal of Biological Chemistry. 270 (40): 23612–23618. doi:10.1016/s0021-9258(17)45857-1. PMID 7559527.

Hermans SJ, Ascher DB, Hancock NC, Holien JK, Michell BJ, Chai SY, et al. (February 2015). "Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides". Protein Science. 24 (2): 190–199. doi:10.2210/pdb4p8q/pdb. PMC 4315657. PMID 25408552.

Mpakali A, Saridakis E, Harlos K, Zhao Y, Papakyriakou A, Kokkala P, et al. (September 2015). "Crystal Structure of Insulin-Regulated Aminopeptidase with Bound Substrate Analogue Provides Insight on Antigenic Epitope Precursor Recognition and Processing". Journal of Immunology. 195 (6): 2842–2851. doi:10.4049/jimmunol.1501103. PMID 26259583.

Mpakali A, Saridakis E, Harlos K, Zhao Y, Kokkala P, Georgiadis D, et al. (April 2017). "Ligand-Induced Conformational Change of Insulin-Regulated Aminopeptidase: Insights on Catalytic Mechanism and Active Site Plasticity". Journal of Medicinal Chemistry. 60 (7): 2963–2972. doi:10.1021/acs.jmedchem.6b01890. PMID 28328206.

Mpakali A, Saridakis E, Giastas P, Maben Z, Stern LJ, Larhed M, et al. (July 2020). "Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor". ACS Medicinal Chemistry Letters. 11 (7): 1429–1434. doi:10.1021/acsmedchemlett.0c00172. PMC 7357224. PMID 32676150.

Descamps D, Evnouchidou I, Caillens V, Drajac C, Riffault S, van Endert P, et al. (2020). "The Role of Insulin Regulated Aminopeptidase in Endocytic Trafficking and Receptor Signaling in Immune Cells". Frontiers in Molecular Biosciences. 7: 583556. doi:10.3389/fmolb.2020.583556. PMC 7606930. PMID 33195428.

Georgiadis D, Ziotopoulou A, Kaloumenou E, Lelis A, Papasava A (2020). "The Discovery of Insulin-Regulated Aminopeptidase (IRAP) Inhibitors: A Literature Review". Frontiers in Pharmacology. 11: 585838. doi:10.3389/fphar.2020.585838. PMC 7538644. PMID 33071797.

Lukaszuk A, Demaegdt H, Szemenyei E, Tóth G, Tymecka D, Misicka A, et al. (April 2008). "Beta-homo-amino acid scan of angiotensin IV". Journal of Medicinal Chemistry. 51 (7): 2291–2296. doi:10.1021/jm701490g. PMID 18386881.

Andersson H, Demaegdt H, Vauquelin G, Lindeberg G, Karlén A, Hallberg M, et al. (November 2010). "Disulfide cyclized tripeptide analogues of angiotensin IV as potent and selective inhibitors of insulin-regulated aminopeptidase (IRAP)". Journal of Medicinal Chemistry. 53 (22): 8059–8071. doi:10.1021/jm100793t. PMID 21047126.

Albiston AL, Morton CJ, Ng HL, Pham V, Yeatman HR, Ye S, et al. (December 2008). "Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase". FASEB Journal. 22 (12): 4209–4217. doi:10.1096/fj.08-112227. PMID 18716029.

Kokkala P, Mpakali A, Mauvais FX, Papakyriakou A, Daskalaki I, Petropoulou I, et al. (October 2016). "Optimization and Structure-Activity Relationships of Phosphinic Pseudotripeptide Inhibitors of Aminopeptidases That Generate Antigenic Peptides". Journal of Medicinal Chemistry. 59 (19): 9107–9123. doi:10.1021/acs.jmedchem.6b01031. PMID 27606717.

Smith RJ, Bryant RG (October 1975). "Metal substitutions incarbonic anhydrase: a halide ion probe study". Biochemical and Biophysical Research Communications. 66 (4): 1281–1286. doi:10.1016/0006-291x(75)90498-2. PMID 3.

Vanga SR, Sävmarker J, Ng L, Larhed M, Hallberg M, Åqvist J, et al. (April 2018). "Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides". ACS Omega. 3 (4): 4509–4521. doi:10.1021/acsomega.8b00595.s003. PMC 6045421. PMID 30023895.

Vourloumis D, Mavridis I, Athanasoulis A, Temponeras I, Koumantou S, Giastas P, et al. (July 2022). "Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-amino Acid Derivatives of Bestatin". J Med Chem. 65 (14): 10098–10117. doi:10.1021/acs.jmedchem.2c00904. PMID 35833347.

Engen K, Vanga SR, Lundbäck T, Agalo F, Konda V, Jensen AJ, et al. (March 2020). "Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors". ChemistryOpen. 9 (3): 325–337. doi:10.1002/open.201900344. PMC 7050655. PMID 32154052.

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Leucyl/cystinyl aminopeptidase (English Wikipedia)

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