MAPK/ERK pathway (English Wikipedia)

Orton RJ, Sturm OE, Vyshemirsky V, Calder M, Gilbert DR, Kolch W (Dec 2005). "Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway". The Biochemical Journal. 392 (Pt 2): 249–61. doi:10.1042/BJ20050908. PMC 1316260. PMID 16293107.
Schulze WX, Deng L, Mann M (2005). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Molecular Systems Biology. 1 (1): 2005.0008. doi:10.1038/msb4100012. PMC 1681463. PMID 16729043.
Zarich N, Oliva JL, Martínez N, et al. (Aug 2006). "Grb2 is a negative modulator of the intrinsic Ras-GEF activity of hSos1". Molecular Biology of the Cell. 17 (8): 3591–7. doi:10.1091/mbc.E05-12-1104. PMC 1525251. PMID 16760435.
Avruch J, Khokhlatchev A, Kyriakis JM, et al. (2001). "Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade". Recent Progress in Hormone Research. 56 (1): 127–55. doi:10.1210/rp.56.1.127. PMID 11237210.
Pende M, Um SH, Mieulet V, et al. (Apr 2004). "S6K1,^(-/-)/S6K2^(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway". Molecular and Cellular Biology. 24 (8): 3112–24. doi:10.1128/MCB.24.8.3112-3124.2004. PMC 381608. PMID 15060135.
Meloche, et al.. “The ERK1/2 Mitogen-Activated Protein Kinase Pathway as a Master Regulator of the G1- to S-Phase Transition.” Oncogene, vol. 26, no. 22, 2007, pp. 3227–3239., doi:10.1038/sj.onc.1210414.
Chambard, Jean-Claude, et al. “ERK Implication in Cell Cycle Regulation.” Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol. 1773, no. 8, 2007, pp. 1299–1310., doi:10.1016/j.bbamcr.2006.11.010.
4. Yao, Guang, et al. “A Bistable Rb-E2F Switch Underlies the Restriction Point.” Nature Cell Biology, vol. 10, no. 4, 2008, pp. 476–482., doi:10.1038/ncb1711.
Albeck, John A G., et al. “Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals.” Molecular Cell, vol. 49, no. 2, 2013, pp. 249–261., doi:10.1016/j.molcel.2012.11.002.
8. Yang, Hee Won, et al. “Competing Memories of Mitogen and p53 Signalling Control Cell-Cycle Entry.” Nature, vol. 549, no. 7672, June 2017, pp. 404–408., doi:10.1038/nature23880.
Yang, Hee Won, et al. “Competing Memories of Mitogen and p53 Signalling Control Cell-Cycle Entry.” Nature, vol. 549, no. 7672, June 2017, pp. 404–408., doi:10.1038/nature23880.
Kedziora, Katarzyna M., and Jeremy E. Purvis. “Cell Biology: The Persistence of Memory.”Nature, vol. 549, no. 7672, June 2017, pp. 343–344., doi:10.1038/nature23549.
Downward J (2003). "Targeting RAS signalling pathways in cancer therapy". Nature Reviews Cancer. 3 (1): 11–22. doi:10.1038/nrc969. PMID 12509763. S2CID 43074411.
Hilger RA, Scheulen ME, Strumberg D (December 2002). "The Ras-Raf-MEK-ERK pathway in the treatment of cancer" (PDF). Onkologie. 25 (6): 511–8. doi:10.1159/000068621. PMID 12566895. S2CID 26673969. Archived from the original on 2012-10-06.
Sebolt-Leopold JS (June 2008). "Advances in the development of cancer therapeutics directed against the RAS-mitogen-activated protein kinase pathway". Clin. Cancer Res. 14 (12): 3651–6. doi:10.1158/1078-0432.CCR-08-0333. PMID 18559577. Archived from the original on 2011-09-06.
Hoshino R, Chatani Y, Yamori T, et al. (January 1999). "Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors". Oncogene. 18 (3): 813–22. doi:10.1038/sj.onc.1202367. PMID 9989833.
McCubrey JA, Steelman LS, Chappell WH, et al. (August 2007). "Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance". Biochim. Biophys. Acta. 1773 (8): 1263–84. doi:10.1016/j.bbamcr.2006.10.001. PMC 2696318. PMID 17126425.
Zheng B, Fiumara P, Li YV, et al. (August 2003). "MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival". Blood. 102 (3): 1019–27. doi:10.1182/blood-2002-11-3507. PMID 12689928.
Calvert VS, Tang Y, Boveia V, Wulfkuhle J, Schutz-Geschwender A, Oliver DM, Liotta LA, Petricoin EF (2004). "Development of Multiplexed Protein Profiling and Detection Using Near Infrared Detection of Reverse-Phase Protein Microarrays". Clinical Proteomics Journal. 1 (1): 81–89. doi:10.1385/CP:1:1:081.

hematologylibrary.org

bloodjournal.hematologylibrary.org

Zheng B, Fiumara P, Li YV, et al. (August 2003). "MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival". Blood. 102 (3): 1019–27. doi:10.1182/blood-2002-11-3507. PMID 12689928.

karger.com

content.karger.com

Hilger RA, Scheulen ME, Strumberg D (December 2002). "The Ras-Raf-MEK-ERK pathway in the treatment of cancer" (PDF). Onkologie. 25 (6): 511–8. doi:10.1159/000068621. PMID 12566895. S2CID 26673969. Archived from the original on 2012-10-06.

nih.gov

pubmed.ncbi.nlm.nih.gov

Orton RJ, Sturm OE, Vyshemirsky V, Calder M, Gilbert DR, Kolch W (Dec 2005). "Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway". The Biochemical Journal. 392 (Pt 2): 249–61. doi:10.1042/BJ20050908. PMC 1316260. PMID 16293107.
Schulze WX, Deng L, Mann M (2005). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Molecular Systems Biology. 1 (1): 2005.0008. doi:10.1038/msb4100012. PMC 1681463. PMID 16729043.
Zarich N, Oliva JL, Martínez N, et al. (Aug 2006). "Grb2 is a negative modulator of the intrinsic Ras-GEF activity of hSos1". Molecular Biology of the Cell. 17 (8): 3591–7. doi:10.1091/mbc.E05-12-1104. PMC 1525251. PMID 16760435.
Avruch J, Khokhlatchev A, Kyriakis JM, et al. (2001). "Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade". Recent Progress in Hormone Research. 56 (1): 127–55. doi:10.1210/rp.56.1.127. PMID 11237210.
Pende M, Um SH, Mieulet V, et al. (Apr 2004). "S6K1,^(-/-)/S6K2^(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway". Molecular and Cellular Biology. 24 (8): 3112–24. doi:10.1128/MCB.24.8.3112-3124.2004. PMC 381608. PMID 15060135.
Downward J (2003). "Targeting RAS signalling pathways in cancer therapy". Nature Reviews Cancer. 3 (1): 11–22. doi:10.1038/nrc969. PMID 12509763. S2CID 43074411.
Hilger RA, Scheulen ME, Strumberg D (December 2002). "The Ras-Raf-MEK-ERK pathway in the treatment of cancer" (PDF). Onkologie. 25 (6): 511–8. doi:10.1159/000068621. PMID 12566895. S2CID 26673969. Archived from the original on 2012-10-06.
Sebolt-Leopold JS (June 2008). "Advances in the development of cancer therapeutics directed against the RAS-mitogen-activated protein kinase pathway". Clin. Cancer Res. 14 (12): 3651–6. doi:10.1158/1078-0432.CCR-08-0333. PMID 18559577. Archived from the original on 2011-09-06.
Hoshino R, Chatani Y, Yamori T, et al. (January 1999). "Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors". Oncogene. 18 (3): 813–22. doi:10.1038/sj.onc.1202367. PMID 9989833.
McCubrey JA, Steelman LS, Chappell WH, et al. (August 2007). "Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance". Biochim. Biophys. Acta. 1773 (8): 1263–84. doi:10.1016/j.bbamcr.2006.10.001. PMC 2696318. PMID 17126425.
Zheng B, Fiumara P, Li YV, et al. (August 2003). "MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival". Blood. 102 (3): 1019–27. doi:10.1182/blood-2002-11-3507. PMID 12689928.
Zhang H, Guo H, Zhang YC, Liu M, Ai K, Su YM, Li MH, Li TL (2014). "[Effect of moxibustion intervention on expression of gastric epidermal growth factor receptor and extracellular signal regulated kinase 1/2 expression in rats with gastric ulcer]". Zhen Ci Yan Jiu. 39 (5): 351–7. PMID 25518106.

ncbi.nlm.nih.gov

Orton RJ, Sturm OE, Vyshemirsky V, Calder M, Gilbert DR, Kolch W (Dec 2005). "Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway". The Biochemical Journal. 392 (Pt 2): 249–61. doi:10.1042/BJ20050908. PMC 1316260. PMID 16293107.
Schulze WX, Deng L, Mann M (2005). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Molecular Systems Biology. 1 (1): 2005.0008. doi:10.1038/msb4100012. PMC 1681463. PMID 16729043.
Zarich N, Oliva JL, Martínez N, et al. (Aug 2006). "Grb2 is a negative modulator of the intrinsic Ras-GEF activity of hSos1". Molecular Biology of the Cell. 17 (8): 3591–7. doi:10.1091/mbc.E05-12-1104. PMC 1525251. PMID 16760435.
Pende M, Um SH, Mieulet V, et al. (Apr 2004). "S6K1,^(-/-)/S6K2^(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway". Molecular and Cellular Biology. 24 (8): 3112–24. doi:10.1128/MCB.24.8.3112-3124.2004. PMC 381608. PMID 15060135.
McCubrey JA, Steelman LS, Chappell WH, et al. (August 2007). "Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance". Biochim. Biophys. Acta. 1773 (8): 1263–84. doi:10.1016/j.bbamcr.2006.10.001. PMC 2696318. PMID 17126425.

semanticscholar.org

api.semanticscholar.org

Downward J (2003). "Targeting RAS signalling pathways in cancer therapy". Nature Reviews Cancer. 3 (1): 11–22. doi:10.1038/nrc969. PMID 12509763. S2CID 43074411.
Hilger RA, Scheulen ME, Strumberg D (December 2002). "The Ras-Raf-MEK-ERK pathway in the treatment of cancer" (PDF). Onkologie. 25 (6): 511–8. doi:10.1159/000068621. PMID 12566895. S2CID 26673969. Archived from the original on 2012-10-06.

web.archive.org

Hilger RA, Scheulen ME, Strumberg D (December 2002). "The Ras-Raf-MEK-ERK pathway in the treatment of cancer" (PDF). Onkologie. 25 (6): 511–8. doi:10.1159/000068621. PMID 12566895. S2CID 26673969. Archived from the original on 2012-10-06.
Sebolt-Leopold JS (June 2008). "Advances in the development of cancer therapeutics directed against the RAS-mitogen-activated protein kinase pathway". Clin. Cancer Res. 14 (12): 3651–6. doi:10.1158/1078-0432.CCR-08-0333. PMID 18559577. Archived from the original on 2011-09-06.
Kwong-Kwok Wong (2009). "Recent Developments in Anti-Cancer Agents Targeting the Ras/Raf/ MEK/ERK Pathway" (PDF). Archived from the original (PDF) on 2010-06-16. {{cite journal}}: Cite journal requires |journal= (help)