References analysis of the Wikipedia article "MRN complex" in the English version

atlasgeneticsoncology.org (Global: low place; English: low place)

doi.org (Global: 2^nd place; English: 2^nd place)

Lee, JH; Paull, TT (Apr 2, 2004). "Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex". Science. 304 (5667): 93–6. Bibcode:2004Sci...304...93L. doi:10.1126/science.1091496. PMID 15064416. S2CID 26732864.

Lee, JH; Paull, TT (Apr 22, 2005). "ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex". Science. 308 (5721): 551–4. Bibcode:2005Sci...308..551L. doi:10.1126/science.1108297. PMID 15790808. S2CID 37711373.

Jazayeri A, Balestrini A, Garner E, Haber JE, Costanzo V (2008). "Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity". The EMBO Journal. 27 (14): 1953–1962. doi:10.1038/emboj.2008.128. PMC 2453060. PMID 18596698.

White, MF (2011). "Homologous recombination in the archaea: the means justify the ends". Biochem Soc Trans. 39 (1): 15–9. doi:10.1042/BST0390015. PMID 21265740.

Quaiser, A; Constantinesco, F; White, MF; Forterre, P; Elie, C (2008). "The Mre11 protein interacts with both Rad50 and the HerA bipolar helicase and is recruited to DNA following gamma irradiation in the archaeon Sulfolobus acidocaldarius". BMC Mol Biol. 9: 25. doi:10.1186/1471-2199-9-25. PMC 2288612. PMID 18294364.

Lukaszewicz, A; Howard-Till, RA; Novatchkova, M; Mochizuki, K; Loidl, J (2010). "MRE11 and COM1/SAE2 are required for double-strand break repair and efficient chromosome pairing during meiosis of the protist Tetrahymena". Chromosoma. 119 (5): 505–18. doi:10.1007/s00412-010-0274-9. PMID 20422424. S2CID 12642689.

Lamarche, BJ; Orazio, NI; Weitzman, MD (10 September 2010). "The MRN complex in double-strand break repair and telomere maintenance". FEBS Letters. 584 (17): 3682–95. doi:10.1016/j.febslet.2010.07.029. PMC 2946096. PMID 20655309.

Lukas, Claudia; Falck, Jacob; Bartkova, Jirina; Bartek, Jiri; Lukas, Jiri (24 February 2003). "Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage". Nature Cell Biology. 5 (3): 255–260. doi:10.1038/ncb945. PMID 12598907. S2CID 7061813.

Lavin, M F (10 December 2007). "ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks". Oncogene. 26 (56): 7749–7758. doi:10.1038/sj.onc.1210880. PMID 18066087.

You, Z; Chahwan, C; Bailis, J; Hunter, T; Russell, P (July 2005). "ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1". Molecular and Cellular Biology. 25 (13): 5363–79. doi:10.1128/MCB.25.13.5363-5379.2005. PMC 1156989. PMID 15964794.

Shibata, A; Moiani, D; Arvai, AS; Perry, J; Harding, SM; Genois, MM; Maity, R; van Rossum-Fikkert, S; Kertokalio, A; Romoli, F; Ismail, A; Ismalaj, E; Petricci, E; Neale, MJ; Bristow, RG; Masson, JY; Wyman, C; Jeggo, PA; Tainer, JA (9 January 2014). "DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities". Molecular Cell. 53 (1): 7–18. doi:10.1016/j.molcel.2013.11.003. PMC 3909494. PMID 24316220.

de Jager, M; van Noort, J; van Gent, DC; Dekker, C; Kanaar, R; Wyman, C (November 2001). "Human Rad50/Mre11 is a flexible complex that can tether DNA ends". Molecular Cell. 8 (5): 1129–35. doi:10.1016/s1097-2765(01)00381-1. PMID 11741547.

Williams, RS; Moncalian, G; Williams, JS; Yamada, Y; Limbo, O; Shin, DS; Groocock, LM; Cahill, D; Hitomi, C; Guenther, G; Moiani, D; Carney, JP; Russell, P; Tainer, JA (3 October 2008). "Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair". Cell. 135 (1): 97–109. doi:10.1016/j.cell.2008.08.017. PMC 2681233. PMID 18854158.

Zhu, XD; Küster, B; Mann, M; Petrini, JH; de Lange, T (July 2000). "Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres". Nature Genetics. 25 (3): 347–52. doi:10.1038/77139. PMID 10888888. S2CID 6689794.

Ranganathan, V; Heine, WF; Ciccone, DN; Rudolph, KL; Wu, X; Chang, S; Hai, H; Ahearn, IM; Livingston, DM; Resnick, I; Rosen, F; Seemanova, E; Jarolim, P; DePinho, RA; Weaver, DT (26 June 2001). "Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit". Current Biology. 11 (12): 962–6. doi:10.1016/s0960-9822(01)00267-6. PMID 11448772. S2CID 11631820.

Chai, W; Sfeir, AJ; Hoshiyama, H; Shay, JW; Wright, WE (February 2006). "The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres". EMBO Reports. 7 (2): 225–30. doi:10.1038/sj.embor.7400600. PMC 1369251. PMID 16374507.

Zhong, ZH; Jiang, WQ; Cesare, AJ; Neumann, AA; Wadhwa, R; Reddel, RR (5 October 2007). "Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres". The Journal of Biological Chemistry. 282 (40): 29314–22. doi:10.1074/jbc.M701413200. PMID 17693401.

Stewart GS, Maser RS, Stankovic T, Bressan DA, Kaplan MI, Jaspers NG, Raams A, Byrd PJ, Petrini JH, Taylor AM (1999). "The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder". Cell. 99 (6): 577–87. doi:10.1016/s0092-8674(00)81547-0. PMID 10612394. S2CID 14434655.

Waltes R, Kalb R, Gatei M, Kijas AW, Stumm M, Sobeck A, Wieland B, Varon R, Lerenthal Y, Lavin MF, Schindler D, Dörk T (2009). "Human RAD50 deficiency in a Nijmegen Breakage Syndrome-like disorder". Am J Hum Genet. 84 (5): 605–16. doi:10.1016/j.ajhg.2009.04.010. PMC 2681000. PMID 19409520.

Taylor AM, Rothblum-Oviatt C, Ellis NA, Hickson ID, Meyer S, Crawford TO, Smogorzewska A, Pietrucha B, Weemaes C, Stewart GS (2019). "Chromosome instability syndromes". Nat Rev Dis Primers. 5 (1): 64. doi:10.1038/s41572-019-0113-0. PMC 10617425. PMID 31537806. S2CID 202671095.

Czornak, Kamila; Chughtai, Sanaullah; Chrzanowska, Krystyna H. (December 2008). "Mystery of DNA repair: the role of the MRN complex and ATM kinase in DNA damage repair". Journal of Applied Genetics. 49 (4): 383–396. doi:10.1007/BF03195638. PMID 19029686. S2CID 7387378.

Kavitha, C.V.; Choudhary, Bibha; Raghavan, Sathees C.; Muniyappa, K. (September 2010). "Differential regulation of MRN (Mre11–Rad50–Nbs1) complex subunits and telomerase activity in cancer cells". Biochemical and Biophysical Research Communications. 399 (4): 575–580. doi:10.1016/j.bbrc.2010.07.117. PMID 20682289.

Williams, BR; Mirzoeva, OK; Morgan, WF; Lin, J; Dunnick, W; Petrini, JH (16 April 2002). "A murine model of Nijmegen breakage syndrome". Current Biology. 12 (8): 648–53. doi:10.1016/s0960-9822(02)00763-7. PMID 11967151. S2CID 16989759.

Difilippantonio, S; Celeste, A; Fernandez-Capetillo, O; Chen, HT; Reina San Martin, B; Van Laethem, F; Yang, YP; Petukhova, GV; Eckhaus, M; Feigenbaum, L; Manova, K; Kruhlak, M; Camerini-Otero, RD; Sharan, S; Nussenzweig, M; Nussenzweig, A (July 2005). "Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models". Nature Cell Biology. 7 (7): 675–85. doi:10.1038/ncb1270. PMID 15965469. S2CID 27172515.

Gładkowska-Dura, M; Dzierzanowska-Fangrat, K; Dura, WT; van Krieken, JH; Chrzanowska, KH; van Dongen, JJ; Langerak, AW (November 2008). "Unique morphological spectrum of lymphomas in Nijmegen breakage syndrome (NBS) patients with high frequency of consecutive lymphoma formation". The Journal of Pathology. 216 (3): 337–44. doi:10.1002/path.2418. PMID 18788073. S2CID 20635073.

Steffen, J; Maneva, G; Popławska, L; Varon, R; Mioduszewska, O; Sperling, K (15 December 2006). "Increased risk of gastrointestinal lymphoma in carriers of the 657del5 NBS1 gene mutation". International Journal of Cancer. 119 (12): 2970–3. doi:10.1002/ijc.22280. PMID 16998789.

Gao, R; Singh, R; Kaul, Z; Kaul, SC; Wadhwa, R (June 2015). "Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells". The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 70 (6): 701–13. doi:10.1093/gerona/glu019. PMID 24747666.

Kessenbrock, K; Plaks, V; Werb, Z (2 April 2010). "Matrix metalloproteinases: regulators of the tumor microenvironment". Cell. 141 (1): 52–67. doi:10.1016/j.cell.2010.03.015. PMC 2862057. PMID 20371345.

Voulgari, A; Pintzas, A (December 2009). "Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic". Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1796 (2): 75–90. doi:10.1016/j.bbcan.2009.03.002. PMID 19306912.

Reddel, RR (2014). "Telomere maintenance mechanisms in cancer: clinical implications". Current Pharmaceutical Design. 20 (41): 6361–74. doi:10.2174/1381612820666140630101047. PMC 4262939. PMID 24975603.

Lajud, SA; Nagda, DA; Yamashita, T; Zheng, J; Tanaka, N; Abuzeid, WM; Civantos, A; Bezpalko, O; O'Malley BW, Jr; Li, D (15 December 2014). "Dual disruption of DNA repair and telomere maintenance for the treatment of head and neck cancer". Clinical Cancer Research. 20 (24): 6465–78. doi:10.1158/1078-0432.CCR-14-0176. PMID 25324139.

Farmer, H; McCabe, N; Lord, CJ; Tutt, AN; Johnson, DA; Richardson, TB; Santarosa, M; Dillon, KJ; Hickson, I; Knights, C; Martin, NM; Jackson, SP; Smith, GC; Ashworth, A (14 April 2005). "Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy". Nature. 434 (7035): 917–21. Bibcode:2005Natur.434..917F. doi:10.1038/nature03445. PMID 15829967. S2CID 4364706.

Skvortsov, S; Debbage, P; Lukas, P; Skvortsova, I (April 2015). "Crosstalk between DNA repair and cancer stem cell (CSC) associated intracellular pathways". Seminars in Cancer Biology. 31: 36–42. doi:10.1016/j.semcancer.2014.06.002. PMID 24954010.

Chang, F; Lee, JT; Navolanic, PM; Steelman, LS; Shelton, JG; Blalock, WL; Franklin, RA; McCubrey, JA (March 2003). "Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy". Leukemia. 17 (3): 590–603. doi:10.1038/sj.leu.2402824. PMID 12646949.

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White, MF (2011). "Homologous recombination in the archaea: the means justify the ends". Biochem Soc Trans. 39 (1): 15–9. doi:10.1042/BST0390015. PMID 21265740.

Lavin, M F (10 December 2007). "ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks". Oncogene. 26 (56): 7749–7758. doi:10.1038/sj.onc.1210880. PMID 18066087.

Varon R, Demuth I, Chrzanowska KH (1993). "Nijmegen Breakage Syndrome". GeneReviews. PMID 20301355.

Kuroda, S; Urata, Y; Fujiwara, T (2012). "Ataxia-telangiectasia mutated and the Mre11-Rad50-NBS1 complex: promising targets for radiosensitization". Acta Medica Okayama. 66 (2): 83–92. PMID 22525466.

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MRN complex (English Wikipedia)

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