MTAP (English Wikipedia)

Analysis of information sources in references of the Wikipedia article "MTAP" in English language version.

Last modified: 11:36:42, 11 August 2026 (UTC)

Ref.Un. Ref.Website

Global rank English rank

6429nih.gov

5^th place

3714doi.org

2^nd place

62ensembl.org

630^th place

326^th place

62adsabs.harvard.edu

14^th place

9^th place

42uniprot.org

2,402^nd place

2,501^st place

11genecards.org

low place

11web.archive.org

1^st place

11rcsb.org

low place

8,697^th place

adsabs.harvard.edu (Global: 14^th place; English: 9^th place)

ui.adsabs.harvard.edu

Barekatain Y, Ackroyd JJ, Yan VC, Khadka S, Wang L, Chen KC, et al. (July 2021). "Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine". Nature Communications. 12 (1) 4228. Bibcode:2021NatCo..12.4228B. doi:10.1038/s41467-021-24240-3. PMC 8270912. PMID 34244484.
Nobori T, Takabayashi K, Tran P, Orvis L, Batova A, Yu AL, Carson DA (June 1996). "Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers". Proceedings of the National Academy of Sciences of the United States of America. 93 (12): 6203–6208. Bibcode:1996PNAS...93.6203N. doi:10.1073/pnas.93.12.6203. PMC 39214. PMID 8650244.

doi.org (Global: 2^nd place; English: 2^nd place)

Vodnala M, Ranjbarian F, Pavlova A, de Koning HP, Hofer A (2016). "Methylthioadenosine Phosphorylase Protects the Parasite from the Antitrypanosomal Effect of Deoxyadenosine: implications for the pharmacology of adenosine antimetabolites". Journal of Biological Chemistry. 291 (22): 11717–26. doi:10.1074/jbc.M116.715615. PMC 4882440. PMID 27036940.
Ranjbarian F, Vodnala M, Alzahrani KJ, Ebiloma GU, de Koning HP, Hofer A (2016). "9-(2'-Deoxy-2'-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance". Antimicrobial Agents and Chemotherapy. 61 (6): e02719-16. doi:10.1128/AAC.02719-16. PMC 5444181. PMID 28373184.
Pegg AE, Williams-Ashman HG (November 1969). "Phosphate-stimulated breakdown of 5'-methylthioadenosine by rat ventral prostate". The Biochemical Journal. 115 (2): 241–247. doi:10.1042/bj1150241. PMC 1185095. PMID 5378381.
Della Ragione F, Cartenì-Farina M, Gragnaniello V, Schettino MI, Zappia V (September 1986). "Purification and characterization of 5'-deoxy-5'-methylthioadenosine phosphorylase from human placenta". The Journal of Biological Chemistry. 261 (26): 12324–12329. doi:10.1016/S0021-9258(18)67242-4. PMID 3091600.
Kirovski G, Stevens AP, Czech B, Dettmer K, Weiss TS, Wild P, et al. (March 2011). "Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA)". The American Journal of Pathology. 178 (3): 1145–1152. doi:10.1016/j.ajpath.2010.11.059. PMC 3069916. PMID 21356366.
Barekatain Y, Ackroyd JJ, Yan VC, Khadka S, Wang L, Chen KC, et al. (July 2021). "Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine". Nature Communications. 12 (1) 4228. Bibcode:2021NatCo..12.4228B. doi:10.1038/s41467-021-24240-3. PMC 8270912. PMID 34244484.
Menezes WP, Silva VA, Gomes IN, Rosa MN, Spina ML, Carloni AC, et al. (February 2020). "Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness". Cells. 9 (2): 492. doi:10.3390/cells9020492. PMC 7072758. PMID 32093414.
Xu J, Chang WH, Fong LW, Weiss RH, Yu SL, Chen CH (2019-01-25). "Targeting the insulin-like growth factor-1 receptor in MTAP-deficient renal cell carcinoma". Signal Transduction and Targeted Therapy. 4 2. doi:10.1038/s41392-019-0035-z. PMC 6345872. PMID 30701095.{{cite journal}}: CS1 maint: unflagged free DOI (link)
Hansen LJ, Sun R, Yang R, Singh SX, Chen LH, Pirozzi CJ, et al. (July 2019). "MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation". Cancer Research. 79 (13): 3383–3394. doi:10.1158/0008-5472.CAN-18-1010. PMC 6810595. PMID 31040154.
Nobori T, Takabayashi K, Tran P, Orvis L, Batova A, Yu AL, Carson DA (June 1996). "Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers". Proceedings of the National Academy of Sciences of the United States of America. 93 (12): 6203–6208. Bibcode:1996PNAS...93.6203N. doi:10.1073/pnas.93.12.6203. PMC 39214. PMID 8650244.
Appleby TC, Erion MD, Ealick SE (June 1999). "The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis". Structure. 7 (6): 629–641. doi:10.1016/S0969-2126(99)80084-7. PMID 10404592.
Subhi AL, Diegelman P, Porter CW, Tang B, Lu ZJ, Markham GD, Kruger WD (December 2003). "Methylthioadenosine phosphorylase regulates ornithine decarboxylase by production of downstream metabolites". The Journal of Biological Chemistry. 278 (50): 49868–49873. doi:10.1074/jbc.M308451200. PMID 14506228.
Bertino JR, Waud WR, Parker WB, Lubin M (April 2011). "Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies". Cancer Biology & Therapy. 11 (7): 627–632. doi:10.4161/cbt.11.7.14948. PMC 3084968. PMID 21301207.
Li Y, Wang Y, Wu P (January 2019). "5'-Methylthioadenosine and Cancer: old molecules, new understanding". Journal of Cancer. 10 (4): 927–936. doi:10.7150/jca.27160. PMC 6400808. PMID 30854099.

ensembl.org (Global: 630^th place; English: 326^th place)

may2017.archive.ensembl.org

GRCh38: Ensembl release 89: ENSG00000099810 – Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000062937 – Ensembl, May 2017

genecards.org (Global: low place; English: low place)

"MTAP Gene". www.genecards.org. Retrieved 2021-10-06.

nih.gov (Global: 5^th place; English: 5^th place)

ncbi.nlm.nih.gov

"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"MTAP methylthioadenosine phosphorylase [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2021-12-03.
Vodnala M, Ranjbarian F, Pavlova A, de Koning HP, Hofer A (2016). "Methylthioadenosine Phosphorylase Protects the Parasite from the Antitrypanosomal Effect of Deoxyadenosine: implications for the pharmacology of adenosine antimetabolites". Journal of Biological Chemistry. 291 (22): 11717–26. doi:10.1074/jbc.M116.715615. PMC 4882440. PMID 27036940.
Ranjbarian F, Vodnala M, Alzahrani KJ, Ebiloma GU, de Koning HP, Hofer A (2016). "9-(2'-Deoxy-2'-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance". Antimicrobial Agents and Chemotherapy. 61 (6): e02719-16. doi:10.1128/AAC.02719-16. PMC 5444181. PMID 28373184.
Pegg AE, Williams-Ashman HG (November 1969). "Phosphate-stimulated breakdown of 5'-methylthioadenosine by rat ventral prostate". The Biochemical Journal. 115 (2): 241–247. doi:10.1042/bj1150241. PMC 1185095. PMID 5378381.
Kirovski G, Stevens AP, Czech B, Dettmer K, Weiss TS, Wild P, et al. (March 2011). "Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA)". The American Journal of Pathology. 178 (3): 1145–1152. doi:10.1016/j.ajpath.2010.11.059. PMC 3069916. PMID 21356366.
Barekatain Y, Ackroyd JJ, Yan VC, Khadka S, Wang L, Chen KC, et al. (July 2021). "Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine". Nature Communications. 12 (1) 4228. Bibcode:2021NatCo..12.4228B. doi:10.1038/s41467-021-24240-3. PMC 8270912. PMID 34244484.
Menezes WP, Silva VA, Gomes IN, Rosa MN, Spina ML, Carloni AC, et al. (February 2020). "Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness". Cells. 9 (2): 492. doi:10.3390/cells9020492. PMC 7072758. PMID 32093414.
Xu J, Chang WH, Fong LW, Weiss RH, Yu SL, Chen CH (2019-01-25). "Targeting the insulin-like growth factor-1 receptor in MTAP-deficient renal cell carcinoma". Signal Transduction and Targeted Therapy. 4 2. doi:10.1038/s41392-019-0035-z. PMC 6345872. PMID 30701095.{{cite journal}}: CS1 maint: unflagged free DOI (link)
Hansen LJ, Sun R, Yang R, Singh SX, Chen LH, Pirozzi CJ, et al. (July 2019). "MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation". Cancer Research. 79 (13): 3383–3394. doi:10.1158/0008-5472.CAN-18-1010. PMC 6810595. PMID 31040154.
"MLA CE Course Manual: Molecular Biology Information Resources (Genetics Review: Chromosome Band Numbers)". www.ncbi.nlm.nih.gov. Archived from the original on September 6, 2004. Retrieved 2021-10-06.
Nobori T, Takabayashi K, Tran P, Orvis L, Batova A, Yu AL, Carson DA (June 1996). "Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers". Proceedings of the National Academy of Sciences of the United States of America. 93 (12): 6203–6208. Bibcode:1996PNAS...93.6203N. doi:10.1073/pnas.93.12.6203. PMC 39214. PMID 8650244.
Bertino JR, Waud WR, Parker WB, Lubin M (April 2011). "Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies". Cancer Biology & Therapy. 11 (7): 627–632. doi:10.4161/cbt.11.7.14948. PMC 3084968. PMID 21301207.
Li Y, Wang Y, Wu P (January 2019). "5'-Methylthioadenosine and Cancer: old molecules, new understanding". Journal of Cancer. 10 (4): 927–936. doi:10.7150/jca.27160. PMC 6400808. PMID 30854099.

pubmed.ncbi.nlm.nih.gov

Vodnala M, Ranjbarian F, Pavlova A, de Koning HP, Hofer A (2016). "Methylthioadenosine Phosphorylase Protects the Parasite from the Antitrypanosomal Effect of Deoxyadenosine: implications for the pharmacology of adenosine antimetabolites". Journal of Biological Chemistry. 291 (22): 11717–26. doi:10.1074/jbc.M116.715615. PMC 4882440. PMID 27036940.
Ranjbarian F, Vodnala M, Alzahrani KJ, Ebiloma GU, de Koning HP, Hofer A (2016). "9-(2'-Deoxy-2'-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance". Antimicrobial Agents and Chemotherapy. 61 (6): e02719-16. doi:10.1128/AAC.02719-16. PMC 5444181. PMID 28373184.
Pegg AE, Williams-Ashman HG (November 1969). "Phosphate-stimulated breakdown of 5'-methylthioadenosine by rat ventral prostate". The Biochemical Journal. 115 (2): 241–247. doi:10.1042/bj1150241. PMC 1185095. PMID 5378381.
Della Ragione F, Cartenì-Farina M, Gragnaniello V, Schettino MI, Zappia V (September 1986). "Purification and characterization of 5'-deoxy-5'-methylthioadenosine phosphorylase from human placenta". The Journal of Biological Chemistry. 261 (26): 12324–12329. doi:10.1016/S0021-9258(18)67242-4. PMID 3091600.
Kirovski G, Stevens AP, Czech B, Dettmer K, Weiss TS, Wild P, et al. (March 2011). "Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA)". The American Journal of Pathology. 178 (3): 1145–1152. doi:10.1016/j.ajpath.2010.11.059. PMC 3069916. PMID 21356366.
Barekatain Y, Ackroyd JJ, Yan VC, Khadka S, Wang L, Chen KC, et al. (July 2021). "Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine". Nature Communications. 12 (1) 4228. Bibcode:2021NatCo..12.4228B. doi:10.1038/s41467-021-24240-3. PMC 8270912. PMID 34244484.
Menezes WP, Silva VA, Gomes IN, Rosa MN, Spina ML, Carloni AC, et al. (February 2020). "Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness". Cells. 9 (2): 492. doi:10.3390/cells9020492. PMC 7072758. PMID 32093414.
Xu J, Chang WH, Fong LW, Weiss RH, Yu SL, Chen CH (2019-01-25). "Targeting the insulin-like growth factor-1 receptor in MTAP-deficient renal cell carcinoma". Signal Transduction and Targeted Therapy. 4 2. doi:10.1038/s41392-019-0035-z. PMC 6345872. PMID 30701095.{{cite journal}}: CS1 maint: unflagged free DOI (link)
Hansen LJ, Sun R, Yang R, Singh SX, Chen LH, Pirozzi CJ, et al. (July 2019). "MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation". Cancer Research. 79 (13): 3383–3394. doi:10.1158/0008-5472.CAN-18-1010. PMC 6810595. PMID 31040154.
Nobori T, Takabayashi K, Tran P, Orvis L, Batova A, Yu AL, Carson DA (June 1996). "Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers". Proceedings of the National Academy of Sciences of the United States of America. 93 (12): 6203–6208. Bibcode:1996PNAS...93.6203N. doi:10.1073/pnas.93.12.6203. PMC 39214. PMID 8650244.
Appleby TC, Erion MD, Ealick SE (June 1999). "The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis". Structure. 7 (6): 629–641. doi:10.1016/S0969-2126(99)80084-7. PMID 10404592.
Subhi AL, Diegelman P, Porter CW, Tang B, Lu ZJ, Markham GD, Kruger WD (December 2003). "Methylthioadenosine phosphorylase regulates ornithine decarboxylase by production of downstream metabolites". The Journal of Biological Chemistry. 278 (50): 49868–49873. doi:10.1074/jbc.M308451200. PMID 14506228.
Bertino JR, Waud WR, Parker WB, Lubin M (April 2011). "Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies". Cancer Biology & Therapy. 11 (7): 627–632. doi:10.4161/cbt.11.7.14948. PMC 3084968. PMID 21301207.
Li Y, Wang Y, Wu P (January 2019). "5'-Methylthioadenosine and Cancer: old molecules, new understanding". Journal of Cancer. 10 (4): 927–936. doi:10.7150/jca.27160. PMC 6400808. PMID 30854099.

rcsb.org (Global: low place; English: 8,697^th place)

Bank, RCSB Protein Data. "RCSB PDB - 3OZE: Crystal Structure of human 5'-deoxy-5'-methyladenosine phosphorylase". www.rcsb.org. Retrieved 2021-12-02.

uniprot.org (Global: 2,402^nd place; English: 2,501^st place)

"MTAP - S-methyl-5'-thioadenosine phosphorylase - Homo sapiens (Human) - MTAP gene & protein". www.uniprot.org. Retrieved 2021-12-03.
"UniProtKB - Q13126 (MTAP_Human)". UniProt. Retrieved October 5, 2021.

web.archive.org (Global: 1^st place; English: 1^st place)

"MLA CE Course Manual: Molecular Biology Information Resources (Genetics Review: Chromosome Band Numbers)". www.ncbi.nlm.nih.gov. Archived from the original on September 6, 2004. Retrieved 2021-10-06.

MTAP (English Wikipedia)

adsabs.harvard.edu (Global: 14th place; English: 9th place)

ui.adsabs.harvard.edu

doi.org (Global: 2nd place; English: 2nd place)

ensembl.org (Global: 630th place; English: 326th place)